glutethimide has been researched along with Porphyrias in 9 studies
Glutethimide: A hypnotic and sedative. Its use has been largely superseded by other drugs.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, SM | 1 |
| Pepe, JA | 1 |
| Cable, EE | 1 |
| Lambrecht, RW | 1 |
| Bonkovsky, HL | 1 |
| Kobus, SM | 1 |
| Wong, SG | 1 |
| Marks, GS | 5 |
| Racz, WJ | 2 |
| Creighton, JM | 1 |
| Horváth, T | 1 |
| Gógl, A | 1 |
| Ruzsa, C | 1 |
| Ludány, A | 1 |
| Jávor, T | 1 |
| Schreiner, GE | 1 |
| Teehan, BP | 1 |
| Hunter, AR | 1 |
| Schneck, DW | 2 |
| Tyrrell, DL | 1 |
| Hirsch, GH | 1 |
| Bubbar, GL | 1 |
1 review available for glutethimide and Porphyrias
| Article | Year |
|---|---|
Dialysis of poisons and drugs--annual review.
Topics: Acidosis; Alcohols; Analgesics; Anti-Bacterial Agents; Antidepressive Agents; Barbiturates; Edema; F | 1971 |
8 other studies available for glutethimide and Porphyrias
| Article | Year |
|---|---|
Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Dr | 1994 |
Isolation of regioisomers of N-alkylprotoporphyrin IX from chick embryo liver after treatment with porphyrinogenic xenobiotics.
Topics: Animals; Chick Embryo; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme In | 2001 |
Drug-induced porphyrin biosynthesis. II. Simple procedure for screening drugs for porphyria-inducing activity.
Topics: Animals; Anticonvulsants; Barbiturates; Benzene Derivatives; Chick Embryo; Culture Techniques; Dimet | 1969 |
Drug-induced porphyrin biosynthesis. VII. Species, sex, and developmental differences in the generation of experimental porphyria.
Topics: 17-Ketosteroids; 5-Aminolevulinate Synthetase; Androstanes; Animals; Animals, Newborn; Chick Embryo; | 1972 |
Drug-induced manifestation of hereditary hepatopathy.
Topics: Adult; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Contraceptives, Oral, Combined; Dru | 1974 |
Treatment by artificial ventilation of the lungs.
Topics: Acetylcysteine; Asthma; Barbiturates; Glutethimide; Humans; Humidity; Infections; Intensive Care Uni | 1967 |
Drug-induced porphyrin biosynthesis. 3. Inhibition of drug-induced porphyria by protohemin.
Topics: Acetamides; Allyl Compounds; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; De | 1971 |
Studies of the relationship between chemical structure and porphyria-inducing activity. IV. Investigations in a cell culture system.
Topics: Amides; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Culture Techniques; Fluorometry; Gluta | 1968 |