glutathione disulfide has been researched along with Acute Liver Injury, Drug-Induced in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.56) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 7 (19.44) | 29.6817 |
| 2010's | 22 (61.11) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Abdul-Aziz, AA; Elshehawy, AA; Koutb, F; Mehany, H; Shaban, NZ; Zaki, MM | 1 |
| Mahdavifard, S; Sekhavatmand, N | 1 |
| Chen, JN; Huang, QH; Lai, XP; Liang, JL; Lin, GS; Liu, YH; Su, ZR; Wu, JZ; Wu, X; Xu, LQ | 1 |
| Arakawa, S; Igarashi, I; Kai, K; Maejima, T; Sanbuissho, A; Teranishi, M | 1 |
| Aycan, IÖ; Evliyaoğlu, O; Fırat, U; Kavak, GÖ; Tokgöz, O; Tüfek, A; Turgut, H; Yüksel, MU | 1 |
| Chen, BH; Huang, JH; Lin, WT; Lu, YF; Tien, YH; Wang Hsu, GS | 1 |
| Bajt, ML; Ding, WX; Du, K; Jaeschke, H; McGill, MR; Xie, Y | 1 |
| Breckenridge, DG; Farhood, A; Jaeschke, H; Lebofsky, M; Liles, JT; Ramachandran, A; Xie, Y | 1 |
| Cogliati, B; Crespo Yanguas, S; da Silva, TC; Farhood, A; Jaeschke, H; Lebofsky, M; Maes, M; Maria Monteiro de Araújo, C; McGill, MR; Tiburcio, T; Veloso Alves Pereira, I; Vinken, M; Willebrords, J; Zaidan Dagli, ML | 1 |
| Durham, D; Jaeschke, H; Kennon-McGill, S; McGill, MR | 1 |
| Makino, S; Oda, S; Shirai, Y; Tsuneyama, K; Yokoi, T | 1 |
| Lin, CC; Liu, WH; Yin, MC | 1 |
| Farhood, A; Hong, JY; Jaeschke, H; Lebofsky, M | 1 |
| Acharya, M; Lau-Cam, CA | 1 |
| Abdel-Naim, AB; El-Beshbishy, HA; Mohamadin, AM; Nagy, AA | 1 |
| Jaeschke, H; Lebofsky, M; Ramachandran, A; Weinman, SA | 1 |
| Choi, JH; Kang, JW; Kim, DW; Lee, SM; Sung, YK | 1 |
| Ji, LL; Jiang, P; Liang, QN; Min, Y; Sheng, YC; Wang, ZT; Xia, YY | 1 |
| Bajt, ML; Farhood, A; Jaeschke, H; Lebofsky, M; Lemasters, JJ; Ramachandran, A; Yan, HM | 1 |
| Cervinková, Z; Haňáčková, L; Kučera, O; Lotková, H; Podhola, M; Roušar, T; Staňková, P | 1 |
| Abdelhamid, K; Fatima, H; Jihen, el H; Mohamed Tahar, S; Sonia, S | 1 |
| Ali, A; Ando, Y; Beger, R; Davis, K; Greenhaw, J; Hinson, JA; Muskhelishvili, L; Pence, LM; Roberts, DW; Salminen, WF; Shi, Q; Sun, J; Yang, X | 1 |
| He, YY; Jia, FL; Liu, WX; Zhang, BX | 1 |
| Klaassen, CD; Wu, KC; Zhang, Y | 1 |
| Hashimoto, T; Kobayashi, A; Kondo, K; Kuno, H; Shoda, T; Sugai, S; Suzuki, Y; Takahashi, A; Toyoda, K; Yamada, N | 1 |
| Fettman, MJ; Mason, G; Twedt, DC; Webb, CB | 1 |
| Ha, BJ; Lee, JY | 1 |
| Jun, W; Kim, KH; Lee, H; Lee, HS; Lee, KW; Won, NH | 1 |
| Li, JY; Wang, L; Zhang, XJ | 1 |
| Irita, K; Koga, A; Kurosawa, K; Okabe, H; Tagawa, K; Takahashi, S; Yamakawa, M; Yoshitake, J | 1 |
| Cai, Y; Rikans, LE | 1 |
| Chen, TS; Ray, MB; Srinivasan, C; Williams, WM | 1 |
| Chen, TS; Song, H | 1 |
| Fujihara, Y; Iguchi, S; Kaneo, Y; Kozawa, Y; Mori, H; Tanaka, T | 1 |
| Tiegs, G; Wendel, A | 1 |
1 trial(s) available for glutathione disulfide and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury.
Topics: Acetaminophen; Animals; Antioxidants; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; Erythrocytes; Glutathione; Glutathione Disulfide; Liver; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Time Factors | 2003 |
35 other study(ies) available for glutathione disulfide and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Protective and therapeutic role of mango pulp and eprosartan drug and their anti-synergistic effects against thioacetamide-induced hepatotoxicity in male rats.
Topics: Acrylates; Animals; Antioxidants; Becaplermin; Chemical and Drug Induced Liver Injury; Fibrosis; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Imidazoles; Inflammation; Liver; Male; Mangifera; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Superoxide Dismutase; Thioacetamide; Thiophenes; Tumor Necrosis Factor-alpha | 2022 |
Glutamine Is a Superior Protector Against Lead-Induced Hepatotoxicity in Rats via Antioxidant, Anti-inflammatory, and Chelating Properties.
Topics: Alanine; Albumins; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Drinking Water; gamma-Glutamyltransferase; Glutamine; Glutathione; Glutathione Disulfide; Interleukin-1beta; Lead; Liver; Malondialdehyde; Oxidative Stress; Peroxidase; Rats | 2022 |
Polydatin protects against acetaminophen-induced hepatotoxicity in mice via anti-oxidative and anti-apoptotic activities.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; Aspartate Aminotransferases; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Chemical and Drug Induced Liver Injury; Glucosides; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Hepatocytes; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NADPH Oxidase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Stilbenes | 2018 |
Role of connexin 32 in acetaminophen toxicity in a knockout mice model.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Connexins; Dose-Response Relationship, Drug; Gap Junction beta-1 Protein; Glutathione; Glutathione Disulfide; Immunohistochemistry; Liver; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis | 2014 |
Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Glutathione Disulfide; Oxidoreductases; Rats; Rats, Wistar | 2014 |
Hepatoprotective and anti-oxidant activities of Glossogyne tenuifolia against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Antipyretics; Aspartate Aminotransferases; Asteraceae; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Overdose; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver; Male; Mice, Inbred BALB C; Phytotherapy; Plant Extracts | 2014 |
The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury.
Topics: Animals; Anthracenes; Cell Line; Chemical and Drug Induced Liver Injury; DNA Damage; Enzyme Activation; Furosemide; Glutathione Disulfide; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mice, Inbred C57BL; Mice, Knockout; Receptor-Interacting Protein Serine-Threonine Kinases; Time Factors | 2015 |
Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Disulfide; JNK Mitogen-Activated Protein Kinases; Liver; Male; MAP Kinase Kinase Kinase 5; Mice, Inbred C57BL; Protective Agents; Protein Kinase Inhibitors | 2015 |
Connexin32: a mediator of acetaminophen-induced liver injury?
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Connexins; Cytokines; Gap Junction beta-1 Protein; Glutathione Disulfide; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Proliferating Cell Nuclear Antigen; Protein Binding | 2016 |
Hearing, reactive metabolite formation, and oxidative stress in cochleae after a single acute overdose of acetaminophen: an in vivo study.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cochlea; Drug Overdose; Glutathione Disulfide; Hearing; Male; Mice, Inbred C57BL; Oxidative Stress; Protein Binding | 2016 |
Establishment of a mouse model of enalapril-induced liver injury and investigation of the pathogenesis.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Enalapril; Glutathione; Glutathione Disulfide; Liver; Male; Mice; Mice, Inbred BALB C; Neutrophils; Oxidative Stress | 2017 |
Alleviative effects of s-allyl cysteine and s-ethyl cysteine on MCD diet-induced hepatotoxicity in mice.
Topics: Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Cholesterol; Choline; Choline Deficiency; Cysteine; Diet; Fatty Acid Synthases; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Interleukin-1beta; Interleukin-6; Liver; Liver Diseases; Malate Dehydrogenase; Male; Malondialdehyde; Methionine; Mice; Mice, Inbred C57BL; Random Allocation; Superoxide Dismutase; Triglycerides; Tumor Necrosis Factor-alpha | 2008 |
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.
Topics: Alanine Transaminase; Aldehydes; Animals; Antifibrinolytic Agents; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Diquat; Disease Models, Animal; DNA Fragmentation; Endotoxins; Galactosamine; Glutathione Disulfide; Hepatocytes; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Liver Diseases; Male; Necrosis; Oxidative Stress; Rats; Rats, Inbred F344; Superoxides; Vitamin K 3 | 2009 |
Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Liver; Liver Diseases; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Taurine | 2010 |
Amelioration of tamoxifen-induced liver injury in rats by grape seed extract, black seed extract and curcumin.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Curcumin; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Grape Seed Extract; Lipid Peroxides; Liver; Nigella sativa; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Superoxide Dismutase; Tamoxifen; Tumor Necrosis Factor-alpha; Vitis | 2010 |
The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Drug Overdose; Glutathione; Glutathione Disulfide; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Necrosis; Oxidative Stress; Signal Transduction; Superoxide Dismutase | 2011 |
Protective effects of Mg-CUD against D-galactosamine-induced hepatotoxicity in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Gene Expression Regulation, Enzymologic; Glutathione Disulfide; Heme Oxygenase-1; I-kappa B Kinase; Inflammation; Interleukin-10; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Liver; Male; NF-kappa B; Organometallic Compounds; Oxidative Stress; Phosphoproteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transaminases; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid | 2011 |
The difference of glutathione antioxidant system in newly weaned and young mice liver and its involvement in isoline-induced hepatotoxicity.
Topics: Age Factors; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Liver; Male; Mice; Mice, Inbred ICR; Pyrrolizidine Alkaloids; Weaning | 2011 |
Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Apoptosis Inducing Factor; Blotting, Western; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Drug Overdose; Glutathione Disulfide; Hepatocytes; Immunohistochemistry; In Situ Nick-End Labeling; Liver; Male; Mice; Mitochondria, Liver; Necrosis; Oxidative Stress; Peroxynitrous Acid; Reactive Oxygen Species | 2011 |
Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen.
Topics: Acetaminophen; Animals; Biomarkers; Caspase 3; Chemical and Drug Induced Liver Injury; Cholesterol; Disease Models, Animal; Disease Susceptibility; Electron Transport Chain Complex Proteins; Fatty Liver; Glutathione; Glutathione Disulfide; Liver; Male; Malondialdehyde; Necrosis; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Risk Factors; Severity of Illness Index; Time Factors; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha | 2012 |
Interrelationships between cadmium, zinc and antioxidants in the liver of the rat exposed orally to relatively high doses of cadmium and zinc.
Topics: Animals; Antioxidants; Cadmium; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Chlorides; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Zinc; Zinc Compounds | 2011 |
Changes in mouse liver protein glutathionylation after acetaminophen exposure.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Disulfide; Hepatocytes; Liver; Male; Mice; Mice, Inbred Strains; Necrosis; Protein Processing, Post-Translational; Proteins | 2012 |
Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.
Topics: 5-Methoxypsoralen; Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methoxsalen; Mice; Mice, Inbred C57BL; Oxidative Stress | 2012 |
Nrf2 protects against diquat-induced liver and lung injury.
Topics: Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Diquat; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Herbicides; Inbreeding; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Survival Analysis; Thiobarbituric Acid Reactive Substances | 2012 |
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatine; Creatinine; Diet; Glutathione; Glutathione Disulfide; Lactic Acid; Male; Malnutrition; Nutritional Status; Pyruvic Acid; Rats; Risk Factors; Taurine | 2012 |
The effect of chondroitin sulfate against CCl4-induced hepatotoxicity.
Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Chondroitin Sulfates; Disease Models, Animal; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2003 |
Antioxidant effects of aqueous extract of Terminalia chebula in vivo and in vitro.
Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Chemical and Drug Induced Liver Injury; Ferric Compounds; Flavonoids; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hepatocytes; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Oxidative Stress; Phenols; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Terminalia; Tetrazolium Salts; Thiazoles | 2005 |
[Cytoprotective effect of neurotensin on acetaminophen induced liver injury in relation to glutathione system].
Topics: Acetaminophen; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Liver; Male; Mice; Neurotensin | 1994 |
Increased sinusoidal efflux of reduced and oxidized glutathione in rats with endotoxin/D-galactosamine hepatitis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endotoxins; Galactosamine; Glutathione; Glutathione Disulfide; Liver; Male; Osmolar Concentration; Rats; Rats, Wistar | 1994 |
Dithiothreitol reversal of allyl alcohol cytotoxicity in isolated rat hepatocytes.
Topics: 1-Propanol; Animals; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dithiothreitol; Drug Interactions; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Propanols; Proteins; Rats; Rats, Inbred F344; Sulfhydryl Compounds | 1994 |
Prevention of acetaminophen-induced liver toxicity by 2(R,S)-n-propylthiazolidine-4(R)-carboxylic acid in mice.
Topics: Acetaminophen; Aldehydes; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Prodrugs; Protective Agents; Thiazoles | 2001 |
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL | 2001 |
Intrahepatic delivery of glutathione by conjugation to dextran.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chromatography, Gel; Chromatography, High Pressure Liquid; Dextrans; Fluorometry; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Prodrugs | 1989 |
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver Injury; Dexamethasone; Diethylcarbamazine; Endotoxins; Galactosamine; Glutathione; Glutathione Disulfide; Hepatitis, Animal; Ibuprofen; Indomethacin; Isoindoles; L-Iditol 2-Dehydrogenase; Male; Mice; Organoselenium Compounds; Selenium; Time Factors | 1986 |