glutaric acid has been researched along with Nerve Degeneration in 7 studies
glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report three cases of L-2-hydroxyglutaric acidemia and three cases of Canavan disease." | 7.69 | Clinical and magnetic resonance imaging features of L-2-hydroxyglutaric acidemia: report of three cases in comparison with Canavan disease. ( Aktan, G; Erdem, G; Jacobs, C; Renda, Y; Saatçi, I; Schutgens, RB; Simşek, A; Topçu, M; Wanders, RJ, 1996) |
| "The association of macrocephaly, dystonia, and bilateral temporal arachnoid cysts, shown either by computed tomography or magnetic resonance imaging, seems to be diagnostic of glutaric aciduria type 1." | 5.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "We report three cases of L-2-hydroxyglutaric acidemia and three cases of Canavan disease." | 3.69 | Clinical and magnetic resonance imaging features of L-2-hydroxyglutaric acidemia: report of three cases in comparison with Canavan disease. ( Aktan, G; Erdem, G; Jacobs, C; Renda, Y; Saatçi, I; Schutgens, RB; Simşek, A; Topçu, M; Wanders, RJ, 1996) |
| " All three acids were neurotoxic in a dose-dependent manner; however, GA and 3GA were both more toxic than QUIN." | 1.31 | IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures. ( Bjugstad, KB; Freed, CR; Goodman, S; Zawada, WM, 2001) |
| "The association of macrocephaly, dystonia, and bilateral temporal arachnoid cysts, shown either by computed tomography or magnetic resonance imaging, seems to be diagnostic of glutaric aciduria type 1." | 1.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kölker, S | 1 |
| Koeller, DM | 1 |
| Okun, JG | 1 |
| Hoffmann, GF | 1 |
| Lund, TM | 1 |
| Christensen, E | 2 |
| Kristensen, AS | 1 |
| Schousboe, A | 1 |
| Lund, AM | 1 |
| Gerstner, B | 1 |
| Gratopp, A | 1 |
| Marcinkowski, M | 1 |
| Sifringer, M | 1 |
| Obladen, M | 1 |
| Bührer, C | 1 |
| Martínez-Lage, JF | 1 |
| Casas, C | 1 |
| Fernández, MA | 1 |
| Puche, A | 1 |
| Rodriguez Costa, T | 1 |
| Poza, M | 1 |
| Topçu, M | 1 |
| Erdem, G | 1 |
| Saatçi, I | 1 |
| Aktan, G | 1 |
| Simşek, A | 1 |
| Renda, Y | 1 |
| Schutgens, RB | 1 |
| Wanders, RJ | 1 |
| Jacobs, C | 1 |
| Flott-Rahmel, B | 1 |
| Falter, C | 1 |
| Schluff, P | 1 |
| Fingerhut, R | 1 |
| Jakobs, C | 1 |
| Musshoff, U | 1 |
| Fautek, JD | 1 |
| Deufel, T | 1 |
| Ludolph, A | 1 |
| Ullrich, K | 1 |
| Bjugstad, KB | 1 |
| Zawada, WM | 1 |
| Goodman, S | 1 |
| Freed, CR | 1 |
1 review available for glutaric acid and Nerve Degeneration
| Article | Year |
|---|---|
Pathomechanisms of neurodegeneration in glutaryl-CoA dehydrogenase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child, Preschool; | 2004 |
6 other studies available for glutaric acid and Nerve Degeneration
| Article | Year |
|---|---|
On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1.
Topics: Animals; Brain Diseases, Metabolic, Inborn; Cell Death; Cells, Cultured; Cerebral Cortex; Corpus Str | 2004 |
Glutaric acid and its metabolites cause apoptosis in immature oligodendrocytes: a novel mechanism of white matter degeneration in glutaryl-CoA dehydrogenase deficiency.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Base Sequence; Brain Diseases, Metabolic, Inbor | 2005 |
Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1.
Topics: Arachnoid Cysts; Brain; Brain Diseases; Carnitine; Dystonia; Female; gamma-Aminobutyric Acid; Glutar | 1994 |
Clinical and magnetic resonance imaging features of L-2-hydroxyglutaric acidemia: report of three cases in comparison with Canavan disease.
Topics: Canavan Disease; Cerebellar Nuclei; Child; Child, Preschool; Female; Glutarates; Humans; Magnetic Re | 1996 |
Nerve cell lesions caused by 3-hydroxyglutaric acid: a possible mechanism for neurodegeneration in glutaric acidaemia I.
Topics: Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Electrophysiology; Glutarates | 1997 |
IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fibroblast | 2001 |