glutaric acid has been researched along with Multiple Sclerosis in 1 studies
glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "While progressive CNS demyelination has occurred in patients with defective peroxisomal very long-chain fatty acid oxidation, this is the 1st time it has occurred with defective mitochondrial beta oxidation." | 1.28 | Juvenile multiple sclerosis-like episodes associated with a defect of mitochondrial beta oxidation. ( Buist, NR; Burlingame, TG; Kennaway, NG; Powell, BR; Reece, CJ; Rhead, WJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Powell, BR | 1 |
| Kennaway, NG | 1 |
| Rhead, WJ | 1 |
| Reece, CJ | 1 |
| Burlingame, TG | 1 |
| Buist, NR | 1 |
1 other study available for glutaric acid and Multiple Sclerosis
| Article | Year |
|---|---|
Juvenile multiple sclerosis-like episodes associated with a defect of mitochondrial beta oxidation.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Demyelinating Diseases; Diagnosis, Different | 1990 |