glutaric acid has been researched along with Disease Models, Animal in 26 studies
glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by accumulation of glutaric acid (GA) and seizures." | 7.78 | m-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system. ( Brüning, CA; Fighera, MR; Gai, BM; Magni, DV; Nogueira, CW; Quines, CB; Rosa, SG, 2012) |
| "Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by accumulation of glutaric acid (GA) and seizures." | 3.78 | m-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system. ( Brüning, CA; Fighera, MR; Gai, BM; Magni, DV; Nogueira, CW; Quines, CB; Rosa, SG, 2012) |
| " Methylprednisolone (MP) is an important corticosteroid used in the treatment (through inhalation) of lung inflammation associated with asthma." | 3.76 | In vivo efficacy of dendrimer-methylprednisolone conjugate formulation for the treatment of lung inflammation. ( Bassett, DJ; Gao, X; Guru, BR; Inapagolla, R; Kannan, RM; Kurtoglu, YE; Lieh-Lai, M, 2010) |
| "Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by striatal degeneration, seizures, and accumulation of glutaric acid (GA)." | 3.74 | Creatine decreases convulsions and neurochemical alterations induced by glutaric acid in rats. ( Ferreira, J; Fighera, MR; Fiorenza, NG; Furian, AF; Magni, DV; Mello, CF; Oliveira, MS; Royes, LF, 2007) |
| "The glutaric acidurias are a group of inborn errors of metabolism with different etiologies." | 1.62 | Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains. ( Argmann, C; Bender, A; Dodatko, T; Houten, SM; Leandro, J; Yu, C, 2021) |
| "Glutaric aciduria type I is an inherited defect in L-lysine, L-hydroxylysine and L-tryptophan degradation caused by deficiency of glutaryl-CoA dehydrogenase (GCDH)." | 1.42 | Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I. ( Blank, AE; Burgard, P; Koeller, DM; Kölker, S; Komatsuzaki, S; Mittelbronn, M; Okun, JG; Opp, S; Sauer, SW, 2015) |
| "Glutaric acid (GA) is a neurotoxic metabolite that accumulates in the CNS of patients with glutaric acidemia-I (GA-I), a neurometabolic disease caused by deficient activity of glutaryl-CoA dehydrogenase." | 1.40 | White matter injury induced by perinatal exposure to glutaric acid. ( Barbeito, L; Casanova, G; Fernández, A; Isasi, E; Jiménez, M; Olivera-Bravo, S; Rosillo, JC; Sarlabós, MN, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (57.69) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Ohtsuki, S | 1 |
| Kikkawa, T | 1 |
| Mori, S | 1 |
| Hori, S | 1 |
| Takanaga, H | 1 |
| Otagiri, M | 1 |
| Terasaki, T | 1 |
| Gonzalez Melo, M | 1 |
| Fontana, AO | 1 |
| Viertl, D | 1 |
| Allenbach, G | 1 |
| Prior, JO | 1 |
| Rotman, S | 1 |
| Feichtinger, RG | 1 |
| Mayr, JA | 1 |
| Costanzo, M | 1 |
| Caterino, M | 1 |
| Ruoppolo, M | 1 |
| Braissant, O | 1 |
| Barbey, F | 1 |
| Ballhausen, D | 1 |
| Leandro, J | 2 |
| Dodatko, T | 2 |
| DeVita, RJ | 1 |
| Chen, H | 1 |
| Stauffer, B | 1 |
| Yu, C | 2 |
| Houten, SM | 2 |
| Bender, A | 1 |
| Argmann, C | 1 |
| Thies, B | 1 |
| Meyer-Schwesinger, C | 1 |
| Lamp, J | 1 |
| Schweizer, M | 1 |
| Koeller, DM | 6 |
| Ullrich, K | 1 |
| Braulke, T | 1 |
| Mühlhausen, C | 3 |
| Olivera-Bravo, S | 1 |
| Isasi, E | 1 |
| Fernández, A | 1 |
| Rosillo, JC | 1 |
| Jiménez, M | 1 |
| Casanova, G | 1 |
| Sarlabós, MN | 1 |
| Barbeito, L | 1 |
| Busanello, EN | 1 |
| Fernandes, CG | 1 |
| Martell, RV | 1 |
| Lobato, VG | 1 |
| Goodman, S | 1 |
| Woontner, M | 6 |
| de Souza, DO | 1 |
| Wajner, M | 5 |
| Sauer, SW | 4 |
| Opp, S | 1 |
| Komatsuzaki, S | 1 |
| Blank, AE | 1 |
| Mittelbronn, M | 1 |
| Burgard, P | 1 |
| Okun, JG | 4 |
| Kölker, S | 5 |
| Colín-González, AL | 1 |
| Paz-Loyola, AL | 1 |
| Serratos, I | 1 |
| Seminotti, B | 1 |
| Ribeiro, CA | 2 |
| Leipnitz, G | 1 |
| Souza, DO | 1 |
| Santamaría, A | 1 |
| Inapagolla, R | 1 |
| Guru, BR | 1 |
| Kurtoglu, YE | 1 |
| Gao, X | 1 |
| Lieh-Lai, M | 1 |
| Bassett, DJ | 1 |
| Kannan, RM | 1 |
| Tian, F | 1 |
| Fu, X | 1 |
| Gao, J | 1 |
| Zhang, C | 1 |
| Ning, Q | 1 |
| Luo, X | 1 |
| Magni, DV | 2 |
| Brüning, CA | 1 |
| Gai, BM | 1 |
| Quines, CB | 1 |
| Rosa, SG | 1 |
| Fighera, MR | 2 |
| Nogueira, CW | 1 |
| Hoffmann, GF | 3 |
| Sauer, S | 1 |
| de Mello, CF | 1 |
| Goodman, SI | 6 |
| Funk, CB | 1 |
| Prasad, AN | 1 |
| Del Bigio, MR | 1 |
| Ferreira, Gda C | 2 |
| Viegas, CM | 2 |
| Schuck, PF | 2 |
| Tonin, A | 2 |
| Coelho, Dde M | 1 |
| Dalla-Costa, T | 1 |
| Latini, A | 2 |
| Wyse, AT | 2 |
| Wannmacher, CM | 2 |
| Vargas, CR | 2 |
| Zinnanti, WJ | 3 |
| Lazovic, J | 3 |
| Wolpert, EB | 2 |
| Antonetti, DA | 2 |
| Smith, MB | 2 |
| Connor, JR | 3 |
| Cheng, KC | 3 |
| Fricker, G | 1 |
| Mahringer, A | 1 |
| Müller, I | 1 |
| Crnic, LR | 1 |
| Hörster, F | 1 |
| Harding, CO | 1 |
| Dutra-Filho, CS | 1 |
| Naylor, MC | 1 |
| Negia, M | 1 |
| Noetzel, M | 1 |
| Burns, TC | 1 |
| Demorest, ZL | 1 |
| Low, WC | 1 |
| Housman, C | 1 |
| LaNoue, K | 1 |
| O'Callaghan, JP | 1 |
| Simpson, I | 1 |
| Jacobs, RE | 1 |
| Oliveira, MS | 1 |
| Furian, AF | 1 |
| Fiorenza, NG | 1 |
| Ferreira, J | 1 |
| Mello, CF | 1 |
| Royes, LF | 1 |
| Crnic, LS | 1 |
| Kleinschmidt-DeMasters, B | 1 |
| Stephens, J | 1 |
| Hunt, EL | 1 |
26 other studies available for glutaric acid and Disease Models, Animal
| Article | Year |
|---|---|
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Ma | 2004 |
A knock-in rat model unravels acute and chronic renal toxicity in glutaric aciduria type I.
Topics: Animals; Computational Biology; Disease Models, Animal; Female; Gene Knock-In Techniques; Glomerular | 2021 |
Deletion of 2-aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1.
Topics: 2-Aminoadipic Acid; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; | 2020 |
Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains.
Topics: Acyltransferases; Amino Acid Metabolism, Inborn Errors; Animals; Disease Models, Animal; Glutarates; | 2021 |
Acute renal proximal tubule alterations during induced metabolic crises in a mouse model of glutaric aciduria type 1.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Disease Models, Animal; Gl | 2013 |
White matter injury induced by perinatal exposure to glutaric acid.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Animals, Newborn; Brain Diseases, Metabolic; Cell Dea | 2014 |
Disturbance of the glutamatergic system by glutaric acid in striatum and cerebral cortex of glutaryl-CoA dehydrogenase-deficient knockout mice: possible implications for the neuropathology of glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Cerebral Cortex; Corpus St | 2014 |
Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I.
Topics: Aconitate Hydratase; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic | 2015 |
Toxic synergism between quinolinic acid and organic acids accumulating in glutaric acidemia type I and in disorders of propionate metabolism in rat brain synaptosomes: Relevance for metabolic acidemias.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Disease Models, Ani | 2015 |
In vivo efficacy of dendrimer-methylprednisolone conjugate formulation for the treatment of lung inflammation.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Chemistry, Pharmaceutical; Dendrimers; Disease Models, An | 2010 |
Caspase-3 mediates apoptosis of striatal cells in GA I rat model.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Apoptosis; Brain Diseases, Metabolic; Caspase 3; Cell | 2012 |
m-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Anticonvulsants; Brain Diseases, Metabolic; Disease M | 2012 |
Adult onset glutaric aciduria type I presenting with a leukoencephalopathy.
Topics: Adult; Age of Onset; Animals; Brain; Brain Diseases, Metabolic, Inborn; Child; Disease Models, Anima | 2003 |
Animal models for glutaryl-CoA dehydrogenase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Chiroptera; Disease Models, Animal; Glutarates; Gluta | 2004 |
Preliminary attempts to establish a rat model of striatal injury in glutaric acidaemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Disease Models, Animal; Glutarates; Injections; Lipop | 2004 |
Glutaric acid administration impairs energy metabolism in midbrain and skeletal muscle of young rats.
Topics: Animals; Brain Diseases, Metabolic, Inborn; Carbon Dioxide; Carbon Radioisotopes; Creatine Kinase; D | 2005 |
A diet-induced mouse model for glutaric aciduria type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Blood-Brain Barrier; Capillary Permeability; Corpus S | 2006 |
Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency.
Topics: Amino Acids; Animals; Biological Transport; Blood-Brain Barrier; Blotting, Western; Brain; Carnitine | 2006 |
Lysine intake and neurotoxicity in glutaric aciduria type I: towards a rationale for therapy?
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Diet; Disease Mode | 2006 |
New insights for glutaric aciduria type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Diet; Disease Mode | 2006 |
Energy metabolism is compromised in skeletal muscle of rats chronically-treated with glutaric acid.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Carbon Dioxide; Carbon Radioisotopes; Creatine | 2007 |
Heparan sulfate mediates neuroprotection from degeneration in experimental glutaric aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Antimetabolites; Brain; Bromodeoxyuridine; Child; Dis | 2007 |
Biochemistry and bioenergetics of glutaryl-CoA dehydrogenase deficiency.
Topics: Acyl Coenzyme A; Animals; Blood-Brain Barrier; Brain; Brain Diseases, Metabolic, Inborn; Capillary P | 2007 |
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet | 2007 |
Creatine decreases convulsions and neurochemical alterations induced by glutaric acid in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Creatine; Disease | 2007 |
Biochemical, pathologic and behavioral analysis of a mouse model of glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Mod | 2002 |