glutaric acid has been researched along with Canavan Disease in 3 studies
glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.
Canavan Disease: A rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. Aspartoacylase deficiency leads to an accumulation of N-acetylaspartate in astrocytes. Inheritance may be autosomal recessive or the illness may occur sporadically. This illness occurs more frequently in individuals of Ashkenazic Jewish descent. The neonatal form features the onset of hypotonia and lethargy at birth, rapidly progressing to coma and death. The infantile form features developmental delay, DYSKINESIAS, hypotonia, spasticity, blindness, and megalencephaly. The juvenile form is characterized by ATAXIA; OPTIC ATROPHY; and DEMENTIA. (From Adams et al., Principles of Neurology, 6th ed, p944; Am J Med Genet 1988 Feb;29(2):463-71)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report three cases of L-2-hydroxyglutaric acidemia and three cases of Canavan disease." | 7.69 | Clinical and magnetic resonance imaging features of L-2-hydroxyglutaric acidemia: report of three cases in comparison with Canavan disease. ( Aktan, G; Erdem, G; Jacobs, C; Renda, Y; Saatçi, I; Schutgens, RB; Simşek, A; Topçu, M; Wanders, RJ, 1996) |
| "We report three cases of L-2-hydroxyglutaric acidemia and three cases of Canavan disease." | 3.69 | Clinical and magnetic resonance imaging features of L-2-hydroxyglutaric acidemia: report of three cases in comparison with Canavan disease. ( Aktan, G; Erdem, G; Jacobs, C; Renda, Y; Saatçi, I; Schutgens, RB; Simşek, A; Topçu, M; Wanders, RJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamaguchi, S | 1 |
| Bal, D | 1 |
| Kraska-Dziadecka, A | 1 |
| Gradowska, W | 1 |
| Gryff-Keller, A | 1 |
| Topçu, M | 1 |
| Erdem, G | 1 |
| Saatçi, I | 1 |
| Aktan, G | 1 |
| Simşek, A | 1 |
| Renda, Y | 1 |
| Schutgens, RB | 1 |
| Wanders, RJ | 1 |
| Jacobs, C | 1 |
1 review available for glutaric acid and Canavan Disease
| Article | Year |
|---|---|
[Organic acid disorders: cerebral organic acidemia].
Topics: Brain Diseases, Metabolic; Canavan Disease; Glutarates; Glycerol; Humans; Hydroxybutyrates; Infant; | 2002 |
2 other studies available for glutaric acid and Canavan Disease
| Article | Year |
|---|---|
Investigation of a wide spectrum of inherited metabolic disorders by 13C NMR spectroscopy.
Topics: Biomarkers; Canavan Disease; Glutarates; Hemiterpenes; Humans; Lactic Acid; Magnetic Resonance Spect | 2008 |
Clinical and magnetic resonance imaging features of L-2-hydroxyglutaric acidemia: report of three cases in comparison with Canavan disease.
Topics: Canavan Disease; Cerebellar Nuclei; Child; Child, Preschool; Female; Glutarates; Humans; Magnetic Re | 1996 |