glutaric acid has been researched along with Atrophy in 8 studies
glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute profound dystonia developed in three previously well infants who were found to have glutaryl-CoA dehydrogenase deficiency in cultured skin fibroblasts." | 6.38 | Acute profound dystonia in infants with glutaric acidemia. ( Bergman, I; Claassen, D; Finegold, D; Gartner, JC; Goodman, SI; Roe, CR; Scarano, J; Stanley, C; Zitelli, BJ, 1989) |
| "Glutaryl-CoA dehydrogenase deficiency or glutaric acidemia type I (GA I) is an inherited neurometabolic disorder biochemically characterized by tissue accumulation of predominantly glutaric (GA) and 3-hydroxyglutaric (3OHGA) acids and clinically by severe neurological symptoms and structural brain abnormalities, manifested as progressive cerebral atrophy and acute striatum degeneration following encephalopathic crises, whose pathophysiology is still in debate." | 3.76 | Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. ( de Souza, DF; Gonçalves, CA; Leipnitz, G; Quincozes-Santos, A; Rosa, RB; Seminotti, B; Wajner, M, 2010) |
| "Acute profound dystonia developed in three previously well infants who were found to have glutaryl-CoA dehydrogenase deficiency in cultured skin fibroblasts." | 2.38 | Acute profound dystonia in infants with glutaric acidemia. ( Bergman, I; Claassen, D; Finegold, D; Gartner, JC; Goodman, SI; Roe, CR; Scarano, J; Stanley, C; Zitelli, BJ, 1989) |
| "Cerebral MRI revealed regressive subdural hematoma, but marked frontotemporal atrophy as well." | 1.29 | Subdural hemorrhage as an initial sign of glutaric aciduria type 1: a diagnostic pitfall. ( Emons, D; Haverkamp, F; Kreft, B; Woelfle, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quincozes-Santos, A | 1 |
| Rosa, RB | 1 |
| Leipnitz, G | 1 |
| de Souza, DF | 1 |
| Seminotti, B | 1 |
| Wajner, M | 1 |
| Gonçalves, CA | 1 |
| Kölker, S | 2 |
| Hoffmann, GF | 1 |
| Schor, DS | 1 |
| Feyh, P | 1 |
| Wagner, L | 1 |
| Jeffrey, I | 1 |
| Pourfarzam, M | 1 |
| Okun, JG | 1 |
| Zschocke, J | 1 |
| Baric, I | 1 |
| Bain, MD | 1 |
| Jakobs, C | 1 |
| Chalmers, RA | 1 |
| Funk, CB | 1 |
| Prasad, AN | 1 |
| Frosk, P | 1 |
| Sauer, S | 1 |
| Greenberg, CR | 1 |
| Del Bigio, MR | 1 |
| Brismar, J | 1 |
| Ozand, PT | 1 |
| Woelfle, J | 1 |
| Kreft, B | 1 |
| Emons, D | 1 |
| Haverkamp, F | 1 |
| Pfluger, T | 1 |
| Weil, S | 1 |
| Muntau, A | 1 |
| Willemsen, UF | 1 |
| Hahn, K | 1 |
| Bergman, I | 1 |
| Finegold, D | 1 |
| Gartner, JC | 1 |
| Zitelli, BJ | 1 |
| Claassen, D | 1 |
| Scarano, J | 1 |
| Roe, CR | 1 |
| Stanley, C | 1 |
| Goodman, SI | 1 |
| Amir, N | 1 |
| el-Peleg, O | 1 |
| Shalev, RS | 1 |
| Christensen, E | 1 |
1 review available for glutaric acid and Atrophy
| Article | Year |
|---|---|
Acute profound dystonia in infants with glutaric acidemia.
Topics: Atrophy; Brain; Cerebellum; Dystonia; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Infant; Male; | 1989 |
7 other studies available for glutaric acid and Atrophy
| Article | Year |
|---|---|
Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Astrocytes; Atrophy; Brain Diseases, Metabolic; Cell | 2010 |
Glutaryl-CoA dehydrogenase deficiency: region-specific analysis of organic acids and acylcarnitines in post mortem brain predicts vulnerability of the putamen.
Topics: Acidosis; Acute Disease; Adolescent; Anticonvulsants; Atrophy; Brain; Carnitine; DNA Mutational Anal | 2003 |
Neuropathological, biochemical and molecular findings in a glutaric acidemia type 1 cohort.
Topics: Adolescent; Adult; Aging; Amino Acid Metabolism, Inborn Errors; Atrophy; Basal Ganglia Diseases; Bra | 2005 |
CT and MR of the brain in glutaric acidemia type I: a review of 59 published cases and a report of 5 new patients.
Topics: Atrophy; Brain; Brain Damage, Chronic; Brain Diseases, Metabolic; Child, Preschool; Diagnosis, Diffe | 1995 |
Subdural hemorrhage as an initial sign of glutaric aciduria type 1: a diagnostic pitfall.
Topics: Amino Acid Metabolism, Inborn Errors; Atrophy; Cisterna Magna; Developmental Disabilities; Diagnosis | 1996 |
Glutaric aciduria type I: a serious pitfall if diagnosed too late.
Topics: Atrophy; Brain; Brain Damage, Chronic; Child, Preschool; Diagnosis, Differential; Female; Genes, Rec | 1997 |
Glutaric aciduria type I: clinical heterogeneity and neuroradiologic features.
Topics: Atrophy; Brain; Child; Child, Preschool; Female; Glutarates; Humans; Infant; Male; Tomography, X-Ray | 1987 |