Page last updated: 2024-10-18

glutaric acid and Atrophy

glutaric acid has been researched along with Atrophy in 8 studies

glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Acute profound dystonia developed in three previously well infants who were found to have glutaryl-CoA dehydrogenase deficiency in cultured skin fibroblasts."6.38Acute profound dystonia in infants with glutaric acidemia. ( Bergman, I; Claassen, D; Finegold, D; Gartner, JC; Goodman, SI; Roe, CR; Scarano, J; Stanley, C; Zitelli, BJ, 1989)
"Glutaryl-CoA dehydrogenase deficiency or glutaric acidemia type I (GA I) is an inherited neurometabolic disorder biochemically characterized by tissue accumulation of predominantly glutaric (GA) and 3-hydroxyglutaric (3OHGA) acids and clinically by severe neurological symptoms and structural brain abnormalities, manifested as progressive cerebral atrophy and acute striatum degeneration following encephalopathic crises, whose pathophysiology is still in debate."3.76Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. ( de Souza, DF; Gonçalves, CA; Leipnitz, G; Quincozes-Santos, A; Rosa, RB; Seminotti, B; Wajner, M, 2010)
"Acute profound dystonia developed in three previously well infants who were found to have glutaryl-CoA dehydrogenase deficiency in cultured skin fibroblasts."2.38Acute profound dystonia in infants with glutaric acidemia. ( Bergman, I; Claassen, D; Finegold, D; Gartner, JC; Goodman, SI; Roe, CR; Scarano, J; Stanley, C; Zitelli, BJ, 1989)
"Cerebral MRI revealed regressive subdural hematoma, but marked frontotemporal atrophy as well."1.29Subdural hemorrhage as an initial sign of glutaric aciduria type 1: a diagnostic pitfall. ( Emons, D; Haverkamp, F; Kreft, B; Woelfle, J, 1996)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quincozes-Santos, A1
Rosa, RB1
Leipnitz, G1
de Souza, DF1
Seminotti, B1
Wajner, M1
Gonçalves, CA1
Kölker, S2
Hoffmann, GF1
Schor, DS1
Feyh, P1
Wagner, L1
Jeffrey, I1
Pourfarzam, M1
Okun, JG1
Zschocke, J1
Baric, I1
Bain, MD1
Jakobs, C1
Chalmers, RA1
Funk, CB1
Prasad, AN1
Frosk, P1
Sauer, S1
Greenberg, CR1
Del Bigio, MR1
Brismar, J1
Ozand, PT1
Woelfle, J1
Kreft, B1
Emons, D1
Haverkamp, F1
Pfluger, T1
Weil, S1
Muntau, A1
Willemsen, UF1
Hahn, K1
Bergman, I1
Finegold, D1
Gartner, JC1
Zitelli, BJ1
Claassen, D1
Scarano, J1
Roe, CR1
Stanley, C1
Goodman, SI1
Amir, N1
el-Peleg, O1
Shalev, RS1
Christensen, E1

Reviews

1 review available for glutaric acid and Atrophy

ArticleYear
Acute profound dystonia in infants with glutaric acidemia.
    Pediatrics, 1989, Volume: 83, Issue:2

    Topics: Atrophy; Brain; Cerebellum; Dystonia; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Infant; Male;

1989

Other Studies

7 other studies available for glutaric acid and Atrophy

ArticleYear
Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Astrocytes; Atrophy; Brain Diseases, Metabolic; Cell

2010
Glutaryl-CoA dehydrogenase deficiency: region-specific analysis of organic acids and acylcarnitines in post mortem brain predicts vulnerability of the putamen.
    Neuropediatrics, 2003, Volume: 34, Issue:5

    Topics: Acidosis; Acute Disease; Adolescent; Anticonvulsants; Atrophy; Brain; Carnitine; DNA Mutational Anal

2003
Neuropathological, biochemical and molecular findings in a glutaric acidemia type 1 cohort.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 4

    Topics: Adolescent; Adult; Aging; Amino Acid Metabolism, Inborn Errors; Atrophy; Basal Ganglia Diseases; Bra

2005
CT and MR of the brain in glutaric acidemia type I: a review of 59 published cases and a report of 5 new patients.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:4

    Topics: Atrophy; Brain; Brain Damage, Chronic; Brain Diseases, Metabolic; Child, Preschool; Diagnosis, Diffe

1995
Subdural hemorrhage as an initial sign of glutaric aciduria type 1: a diagnostic pitfall.
    Pediatric radiology, 1996, Volume: 26, Issue:11

    Topics: Amino Acid Metabolism, Inborn Errors; Atrophy; Cisterna Magna; Developmental Disabilities; Diagnosis

1996
Glutaric aciduria type I: a serious pitfall if diagnosed too late.
    European radiology, 1997, Volume: 7, Issue:8

    Topics: Atrophy; Brain; Brain Damage, Chronic; Child, Preschool; Diagnosis, Differential; Female; Genes, Rec

1997
Glutaric aciduria type I: clinical heterogeneity and neuroradiologic features.
    Neurology, 1987, Volume: 37, Issue:10

    Topics: Atrophy; Brain; Child; Child, Preschool; Female; Glutarates; Humans; Infant; Male; Tomography, X-Ray

1987