glutaric acid has been researched along with Astrocytosis in 3 studies
glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.
Excerpt | Relevance | Reference |
---|---|---|
"Glutaryl-CoA dehydrogenase deficiency or glutaric acidemia type I (GA I) is an inherited neurometabolic disorder biochemically characterized by tissue accumulation of predominantly glutaric (GA) and 3-hydroxyglutaric (3OHGA) acids and clinically by severe neurological symptoms and structural brain abnormalities, manifested as progressive cerebral atrophy and acute striatum degeneration following encephalopathic crises, whose pathophysiology is still in debate." | 3.76 | Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. ( de Souza, DF; Gonçalves, CA; Leipnitz, G; Quincozes-Santos, A; Rosa, RB; Seminotti, B; Wajner, M, 2010) |
"Glutaric acid (GA) is a neurotoxic metabolite that accumulates in the CNS of patients with glutaric acidemia-I (GA-I), a neurometabolic disease caused by deficient activity of glutaryl-CoA dehydrogenase." | 1.40 | White matter injury induced by perinatal exposure to glutaric acid. ( Barbeito, L; Casanova, G; Fernández, A; Isasi, E; Jiménez, M; Olivera-Bravo, S; Rosillo, JC; Sarlabós, MN, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Pierozan, P | 1 |
Colín-González, AL | 1 |
Biasibetti, H | 1 |
da Silva, JC | 1 |
Wyse, A | 1 |
Wajner, M | 2 |
Santamaria, A | 1 |
Olivera-Bravo, S | 1 |
Isasi, E | 1 |
Fernández, A | 1 |
Rosillo, JC | 1 |
Jiménez, M | 1 |
Casanova, G | 1 |
Sarlabós, MN | 1 |
Barbeito, L | 1 |
Quincozes-Santos, A | 1 |
Rosa, RB | 1 |
Leipnitz, G | 1 |
de Souza, DF | 1 |
Seminotti, B | 1 |
Gonçalves, CA | 1 |
3 other studies available for glutaric acid and Astrocytosis
Article | Year |
---|---|
Toxic Synergism Between Quinolinic Acid and Glutaric Acid in Neuronal Cells Is Mediated by Oxidative Stress: Insights to a New Toxic Model.
Topics: Animals; Antioxidants; Catalase; Cell Survival; Cerebral Cortex; Coculture Techniques; Dizocilpine M | 2018 |
White matter injury induced by perinatal exposure to glutaric acid.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Animals, Newborn; Brain Diseases, Metabolic; Cell Dea | 2014 |
Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Astrocytes; Atrophy; Brain Diseases, Metabolic; Cell | 2010 |