Page last updated: 2024-10-18

glutaric acid and Astrocytosis

glutaric acid has been researched along with Astrocytosis in 3 studies

glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.

Research Excerpts

ExcerptRelevanceReference
"Glutaryl-CoA dehydrogenase deficiency or glutaric acidemia type I (GA I) is an inherited neurometabolic disorder biochemically characterized by tissue accumulation of predominantly glutaric (GA) and 3-hydroxyglutaric (3OHGA) acids and clinically by severe neurological symptoms and structural brain abnormalities, manifested as progressive cerebral atrophy and acute striatum degeneration following encephalopathic crises, whose pathophysiology is still in debate."3.76Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. ( de Souza, DF; Gonçalves, CA; Leipnitz, G; Quincozes-Santos, A; Rosa, RB; Seminotti, B; Wajner, M, 2010)
"Glutaric acid (GA) is a neurotoxic metabolite that accumulates in the CNS of patients with glutaric acidemia-I (GA-I), a neurometabolic disease caused by deficient activity of glutaryl-CoA dehydrogenase."1.40White matter injury induced by perinatal exposure to glutaric acid. ( Barbeito, L; Casanova, G; Fernández, A; Isasi, E; Jiménez, M; Olivera-Bravo, S; Rosillo, JC; Sarlabós, MN, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pierozan, P1
Colín-González, AL1
Biasibetti, H1
da Silva, JC1
Wyse, A1
Wajner, M2
Santamaria, A1
Olivera-Bravo, S1
Isasi, E1
Fernández, A1
Rosillo, JC1
Jiménez, M1
Casanova, G1
Sarlabós, MN1
Barbeito, L1
Quincozes-Santos, A1
Rosa, RB1
Leipnitz, G1
de Souza, DF1
Seminotti, B1
Gonçalves, CA1

Other Studies

3 other studies available for glutaric acid and Astrocytosis

ArticleYear
Toxic Synergism Between Quinolinic Acid and Glutaric Acid in Neuronal Cells Is Mediated by Oxidative Stress: Insights to a New Toxic Model.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Animals; Antioxidants; Catalase; Cell Survival; Cerebral Cortex; Coculture Techniques; Dizocilpine M

2018
White matter injury induced by perinatal exposure to glutaric acid.
    Neurotoxicity research, 2014, Volume: 25, Issue:4

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Animals, Newborn; Brain Diseases, Metabolic; Cell Dea

2014
Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Astrocytes; Atrophy; Brain Diseases, Metabolic; Cell

2010