glutaral has been researched along with Rhinitis, Allergic, Seasonal in 32 studies
Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Rhinitis, Allergic, Seasonal: Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "12 patients suffering from grass pollen hay fever were treated for 14 weeks pre- and co-seasonally by intranasal self-administration of an aqueous solution of a glutaraldehyde-treated timothy grass pollen allergen." | 9.04 | Use of glutaraldehyde-modified timothy grass pollen extract in nasal hyposensitisation treatment of hay fever. ( Deuschl, H; Johansson, SG; Zetterström, O, 1979) |
| "One hundred patients with hay fever were treated in 1974/5 with a glutaraldehyde-pollen-tyrosine adsorbate, the response to treatment being assessed at the end of the hay fever season by direct questioning of the patient and examination of a daily record card." | 7.65 | A trial of hyposensitization in 1974/5 in the treatment of hay fever using glutaraldehyde-pollen-tyrosine adsorbate. ( Miller, AC, 1976) |
| "12 patients suffering from grass pollen hay fever were treated for 14 weeks pre- and co-seasonally by intranasal self-administration of an aqueous solution of a glutaraldehyde-treated timothy grass pollen allergen." | 5.04 | Use of glutaraldehyde-modified timothy grass pollen extract in nasal hyposensitisation treatment of hay fever. ( Deuschl, H; Johansson, SG; Zetterström, O, 1979) |
| "A direct comparison was made in 112 hay fever patients of hyposensitization treatment with glutaraldehyde-pollen-tyrosine adsorbate (Pollinex) and with alum-precipitated pyridine extract (Alavac-P) which is an accepted form of treatment, its efficacy having been shown by a comparative trial against a placebo preparation." | 5.04 | A comparative trial of hyposensitization in 1973 in the treatment of hay fever using Pollinex and Alavac-P. ( Miller, AC, 1976) |
| "One hundred patients with hay fever were treated in 1974/5 with a glutaraldehyde-pollen-tyrosine adsorbate, the response to treatment being assessed at the end of the hay fever season by direct questioning of the patient and examination of a daily record card." | 3.65 | A trial of hyposensitization in 1974/5 in the treatment of hay fever using glutaraldehyde-pollen-tyrosine adsorbate. ( Miller, AC, 1976) |
| " Dose-response skin tests were performed at baseline and at the end of the trial." | 2.72 | Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule. ( Colás, C; Lezaun, A; Monzón, S; Venturini, M, 2006) |
| " Dose-response skin prick test with each allergen extract was conducted at baseline and at the end of the study." | 2.71 | Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life. ( Alvarez-Cuesta, E; Aragoneses-Gilsanz, E; Berges-Gimeno, P; Cuesta-Herranz, J; Gonzalez-Mancebo, E; Martín-Garcia, C, 2005) |
| "In 27 patients with pollen allergy the nasal lavage was performed before, during and after pollen season." | 2.68 | [Characteristics of hay fever during pollen season with regard to the influence of specific immunotherapy. I. Clinical course and biochemical changes in nasal lavage]. ( Grzegorczyk, J; Kowalski, M; Rozniecka, M; Rozniecki, J; Sliwińska-Kowalska, M; Wojciechowska, B, 1995) |
| " The SDV treatment induced a more pronounced IgG antibody response both in patients and in guinea-pigs receiving the clinical dosage schedule." | 2.64 | A comparative study of an aqueous grass pollen extract and glutaraldehyde-treated grass pollen-tyrosine adsorbate in the treatment of pollenosis. ( Verstraeten, JM; Wheeler, AW, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (56.25) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rauber, MM | 1 |
| Wu, HK | 1 |
| Adams, B | 1 |
| Pickert, J | 1 |
| Bohle, B | 1 |
| Shamji, MH | 1 |
| Pfützner, W | 1 |
| Möbs, C | 1 |
| Alvarez-Cuesta, E | 1 |
| Aragoneses-Gilsanz, E | 1 |
| Martín-Garcia, C | 1 |
| Berges-Gimeno, P | 1 |
| Gonzalez-Mancebo, E | 1 |
| Cuesta-Herranz, J | 1 |
| Colás, C | 1 |
| Monzón, S | 1 |
| Venturini, M | 1 |
| Lezaun, A | 1 |
| Asturias, JA | 1 |
| Ferrer, A | 1 |
| Arilla, MC | 1 |
| Andreu, C | 1 |
| Madariaga, B | 1 |
| Martínez, A | 1 |
| Subiza, J | 1 |
| Feliú, A | 1 |
| Subiza, JL | 1 |
| Uhlig, J | 1 |
| Fernández-Caldas, E | 1 |
| Fal, W | 1 |
| Brańska, B | 1 |
| Latoś, T | 1 |
| Galary, E | 1 |
| Ligeziński, A | 1 |
| Metzger, WJ | 2 |
| Dorminey, HC | 1 |
| Richerson, HB | 1 |
| Weiler, JM | 1 |
| Donnelly, A | 1 |
| Moran, D | 1 |
| Small, P | 2 |
| Shapiro, M | 1 |
| Medrala, W | 1 |
| Małolepszy, J | 2 |
| Wolańczyk-Medrala, A | 1 |
| Wrzyszcz, M | 1 |
| Rybakiewicz, R | 1 |
| Litwa, M | 1 |
| Rozniecka, M | 2 |
| Kowalski, M | 1 |
| Grzegorczyk, J | 2 |
| Wojciechowska, B | 2 |
| Sliwińska-Kowalska, M | 2 |
| Rozniecki, J | 2 |
| Kowałski, ML | 1 |
| Boznański, A | 1 |
| Pirogowicz, I | 1 |
| Widerska, A | 1 |
| Hebrowska, A | 1 |
| Foucard, T | 1 |
| Johansson, SG | 3 |
| Verstraeten, JM | 1 |
| Wheeler, AW | 3 |
| Gniazdowski, R | 1 |
| Deuschl, H | 1 |
| Zetterström, O | 1 |
| Weisnagel, J | 1 |
| Jarisch, R | 1 |
| Cockcroft, DW | 1 |
| Cuff, MT | 1 |
| Tarlo, SM | 1 |
| Dolovich, J | 1 |
| Hargreave, FE | 2 |
| Patterson, R | 1 |
| Zeiss, R | 1 |
| Irons, JS | 1 |
| Pruzansky, JJ | 1 |
| Suszko, IM | 1 |
| Levitz, D | 1 |
| Miller, AC | 3 |
| Rogala, B | 1 |
| Jarzab, J | 1 |
| Karawajczyk, M | 1 |
| Jawor, B | 1 |
| Rogala, E | 1 |
| Bonifazi, F | 1 |
| Antonicelli, L | 1 |
| Bilò, MB | 1 |
| Pucci, S | 1 |
| Taylor, IH | 1 |
| Youlten, LJ | 2 |
| Resta, O | 1 |
| Carnimeo, N | 1 |
| Foschino, MP | 1 |
| Taylor, I | 1 |
| Kruszewski, J | 1 |
| Juniper, EF | 1 |
| Kline, PA | 1 |
| Ramsdale, EH | 1 |
| Ko, HS | 1 |
| Chen, SJ | 1 |
| Jaworska, E | 1 |
| Zak-Nejmark, T | 1 |
| Nadobna, G | 1 |
| Ossos, M | 1 |
| Liebhart, J | 1 |
| Mullan, N | 1 |
| Overell, BG | 1 |
| Tees, EC | 1 |
| Wheeler, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blinded, Placebo-Controlled, Prospective, Multicenter CT to Evaluate Efficacy and Safety of Subcutaneous Immunotherapy in Subjects With Rhinitis With/Without Mild to Moderate Asthma Sensitized to Olive and Grass Pollen[NCT04891237] | Phase 3 | 180 participants (Anticipated) | Interventional | 2021-06-14 | Recruiting | ||
| Prospective, Randomized, Placebo-controlled, Multi-center Trial Comparing the Efficacy and Safety of Subcutaneous Immunotherapy With a Mixture of Grasses and Mites at Adequate Doses Versus Monotherapy, for the Treatment of Allergy[NCT04874714] | Phase 3 | 18 participants (Actual) | Interventional | 2021-04-30 | Terminated (stopped due to Due to the low recruitment rate since the start of the trial) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 trials available for glutaral and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life.
Topics: Adolescent; Adult; Asthma; Cross-Linking Reagents; Dose-Response Relationship, Immunologic; Double-B | 2005 |
Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule.
Topics: Adolescent; Adult; Allergens; Asthma; Conjunctivitis, Allergic; Desensitization, Immunologic; Double | 2006 |
Tolerance and immunological changes of chemically modified allergen vaccine of Parietaria judaica in accelerated schedules.
Topics: Adolescent; Adult; Aged; Allergens; Antigens, Plant; Chemical Phenomena; Chemistry, Physical; Desens | 2007 |
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration | 2008 |
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration | 2008 |
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration | 2008 |
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration | 2008 |
Clinical and immunologic evaluation of glutaraldehyde-modified tyrosine-adsorbed short ragweed extract: a double-blind, placebo-controlled trial.
Topics: Aldehydes; Antibody Specificity; Antigen-Antibody Complex; Binding, Competitive; Clinical Trials as | 1981 |
[Spontaneous histamine release by basophils and bronchial hyperreactivity in patients with hay fever].
Topics: Allergens; Antigens, Plant; Basophils; Bronchial Hyperreactivity; Drug Combinations; Glutaral; Hista | 1995 |
[Characteristics of hay fever during pollen season with regard to the influence of specific immunotherapy. I. Clinical course and biochemical changes in nasal lavage].
Topics: Adult; Albumins; Allergens; Antigens, Plant; Drug Combinations; Female; Glutaral; Humans; Immunother | 1995 |
[Course of hay fever during the pollen season with respect to the effect of specific immunotherapy. II. Cytologic changes and chemotactic activity in nasal lavage].
Topics: Adult; Allergens; Antigens, Plant; Chemotaxis, Leukocyte; Drug Combinations; Eosinophils; Female; Gl | 1995 |
A comparative study of an aqueous grass pollen extract and glutaraldehyde-treated grass pollen-tyrosine adsorbate in the treatment of pollenosis.
Topics: Adult; Animals; Antigen-Antibody Complex; Female; Glutaral; Guinea Pigs; Humans; Immunoglobulin E; I | 1978 |
Use of glutaraldehyde-modified timothy grass pollen extract in nasal hyposensitisation treatment of hay fever.
Topics: Aldehydes; Allergens; Cell Extracts; Desensitization, Immunologic; Glutaral; Humans; Immunoglobulin | 1979 |
Allergen injection therapy with glutaraldehyde-modified--ragweed pollen-tyrosine adsorbate. A double-blind trial.
Topics: Aldehydes; Allergens; Antigen-Antibody Complex; Clinical Trials as Topic; Glutaral; Humans; Immunogl | 1977 |
A comparative trial of hyposensitization in 1973 in the treatment of hay fever using Pollinex and Alavac-P.
Topics: Adolescent; Adult; Aldehydes; Alum Compounds; Antigens, Plant; Child; Clinical Trials as Topic; Dese | 1976 |
Hyposensitization therapy of Parietaria-sensitive patients with a tyrosine adsorbed allergoid, Pollinex Parietaria (Bencard Parietaria).
Topics: Adult; Allergens; Allergoids; Antigens, Plant; Desensitization, Immunologic; Drug Combinations; Fema | 1991 |
Pollinex Parietaria (Bencard Parietaria), a new allergoid for treatment of patients sensitive to Parietaria pollen.
Topics: Adult; Allergens; Allergoids; Antigens, Plant; Desensitization, Immunologic; Drug Combinations; Fema | 1991 |
Comparison of the efficacy and side effects of aqueous steroid nasal spray (budesonide) and allergen-injection therapy (Pollinex-R) in the treatment of seasonal allergic rhinoconjunctivitis.
Topics: Aldehydes; Allergens; Antigens, Plant; Budesonide; Conjunctivitis, Allergic; Desensitization, Immuno | 1990 |
Glutaraldehyde-pollen-tyrosine: clinical and immunological studies.
Topics: Aldehydes; Antibodies; Glutaral; Humans; Immunoglobulin E; Immunoglobulin G; Plant Extracts; Plants; | 1974 |
16 other studies available for glutaral and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
Birch pollen allergen-specific immunotherapy with glutaraldehyde-modified allergoid induces IL-10 secretion and protective antibody responses.
Topics: Allergens; Allergoids; Antibody Formation; Antigens, Plant; Betula; Glutaral; Humans; Immunity, Cell | 2019 |
[Histamine level of basophils in children with pollinosis treated with pollinex].
Topics: Adolescent; Aldehydes; Allergens; Antigens, Plant; Basophils; Child; Drug Combinations; Female; Glut | 1984 |
[Radioimmunologic tests in specific immunotherapy of atopic rhinitis].
Topics: Adolescent; Adult; Aldehydes; Allergens; Antigens; Antigens, Dermatophagoides; Antigens, Plant; Dese | 1984 |
Immunotherapy with glutaraldehyde treated tyrosine adsorbed grass pollen in the treatment of allergic rhinitis.
Topics: Aldehydes; Allergens; Antigen-Antibody Complex; Antigens, Plant; Complement System Proteins; Desensi | 1981 |
Modified ragweed extract.
Topics: Adult; Aldehydes; Allergens; Anaphylaxis; Antigens, Plant; Drug Combinations; Female; Glutaral; Huma | 1982 |
[Effect of immunotherapy on selected immunologic indices in children with pollinosis].
Topics: Adolescent; Allergens; Antigens, Plant; CD4-CD8 Ratio; Child; Drug Combinations; Female; Glutaral; H | 1996 |
Immunological studies in vitro and in vivo of children with pollenosis given immunotherapy with an aqueous and a glutaraldehyde-treated tyrosine-absorbed grass pollen extract.
Topics: Adsorption; Child; Desensitization, Immunologic; Glutaral; Histamine Release; Humans; Immunoglobulin | 1976 |
[Treatment of hay fever with "Pollinex"].
Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aldehydes; Allergens; Antigens, Plant; Desensitization, | 1978 |
[A new desensitization agent in the treatment of ragweed-induced seasonal allergic rhinitis (hay fever) in children: MRTA (modified ragweed tyrosine adsorbate)].
Topics: Aldehydes; Child; Desensitization, Immunologic; Double-Blind Method; Drug Combinations; Drug Evaluat | 1979 |
[Glutarladehyde-pollen-tyrosine hyposensitization. Course control of therapy using RIST and RAST].
Topics: Antibodies; Desensitization, Immunologic; Drug Evaluation; Follow-Up Studies; Glutaral; Humans; Immu | 1977 |
Comparison of polymerized and unpolymerized antigen E for immunotherapy of ragweed allergy.
Topics: Adult; Allergens; Antibodies; Desensitization, Immunologic; Female; Glutaral; Humans; Immunity, Cell | 1976 |
A trial of hyposensitization in 1974/5 in the treatment of hay fever using glutaraldehyde-pollen-tyrosine adsorbate.
Topics: Adolescent; Adult; Aldehydes; Antigen-Antibody Complex; Child; Desensitization, Immunologic; Female; | 1976 |
Effect of specific immunotherapy on IgE immune complexes in seasonal allergic rhinitis.
Topics: Adolescent; Adult; Allergens; Antigen-Antibody Complex; Antigens, Plant; Desensitization, Immunologi | 1992 |
[Changes in allergen-specific IgG-4 during desensitization of patients with hay fever and those sensitized to housedust allergens].
Topics: Adult; Air Pollutants; Air Pollution, Indoor; Allergens; Animals; Antigens, Dermatophagoides; Antige | 1991 |
IgG and IgE antibody response following Pollinex-R immunotherapy.
Topics: Adolescent; Adult; Aged; Aldehydes; Allergens; Antigens, Plant; Child; Desensitization, Immunologic; | 1987 |
The effect of immunotherapy in hayfever patients on histamine binding capacity of blood serum proteins.
Topics: Adult; Aldehydes; Allergens; Antigens, Plant; Blood Proteins; Desensitization, Immunologic; Drug Com | 1987 |