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glutaral and Prosthesis Durability

glutaral has been researched along with Prosthesis Durability in 39 studies

Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.

Research Excerpts

ExcerptRelevanceReference
"Steroid treatment decreased inflammation and antibody rise in the xenogeneic groups (P<0."1.33Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection. ( Churchill, TA; Korbutt, GS; Koshal, A; Manji, RA; Nijjar, NK; Rajotte, RV; Rayner, DC; Ross, DB; Zhu, LF, 2006)
"Thus glutaraldehyde-treated allografts failed because of extensive calcification, whereas antibiotic-preserved allografts underwent deterioration of connective tissue and infiltration by inflammatory cells."1.29A comparison of failure modes of glutaraldehyde-treated versus antibiotic-preserved mitral valve allografts implanted in sheep. ( Ferrans, VJ; Jones, M; Tamura, K; Yamada, I, 1995)
"Glutaraldehyde pretreatment of bioprosthetic heart valves is the major pathogenic factor in their calcific degeneration."1.29No-react detoxification process: a superior anticalcification method for bioprostheses. ( Abolhoda, A; Allen, KR; Bogden, JD; Gabbay, S; Han, S; Kemp, FW; Lu, Q; McCormick, JR; Oyarzun, JR; Yu, S, 1996)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.26)18.7374
1990's18 (46.15)18.2507
2000's9 (23.08)29.6817
2010's6 (15.38)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Whelan, A1
Williams, E1
Nolan, DR1
Murphy, B1
Gunning, PS1
O'Reilly, D1
Lally, C1
Liu, Z1
Wang, Y1
Xie, F1
Liu, X1
Li, F1
Dong, N1
Zhang, W1
Sacks, MS1
David, TE1
Armstrong, S1
Maganti, M1
Butany, J1
Feindel, CM1
Bos, J1
Kriegs, M1
Kanellopoulou, D1
Koutsoukos, PG1
Mavrilas, D1
Glasmacher, B1
Lozonschi, L1
Bombien, R1
Osaki, S1
Hu, J1
Snell, D1
Edwards, NM1
Cremer, J1
Lutter, G2
Braile, MC1
Carnevalli, NC1
Goissis, G1
Ramirez, VA1
Braile, DM1
Guldner, NW1
Bastian, F1
Weigel, G1
Zimmermann, H1
Maleika, M1
Scharfschwerdt, M1
Rohde, D1
Sievers, HH1
de Buhr, W1
Pfeifer, S1
Slotta-Huspenina, J1
Wintermantel, E1
Goetz, WA1
Claramunt, R1
Alvarez-Ayuso, L1
García-Páez, JM1
Ros, A1
Casado, MC1
Simionescu, DT2
Lovekamp, JJ2
Vyavahare, NR2
Manji, RA1
Zhu, LF1
Nijjar, NK1
Rayner, DC1
Korbutt, GS1
Churchill, TA1
Rajotte, RV1
Koshal, A1
Ross, DB1
Santos, PC1
Gerola, LR1
Casagrande, I1
Buffolo, E1
Cheung, DT1
Tamura, K1
Jones, M1
Yamada, I1
Ferrans, VJ2
Geiger, AW1
Zarubin, AM1
Deiwick, M1
Asfour, B1
Fahrenkamp, A1
Hertel, M1
von Bally, G1
Scheld, HH1
Purinya, B1
Kasyanov, V1
Volkolakov, J1
Latsis, R1
Tetere, G1
Sakai, H1
Hirsch, D1
Drader, J1
Pathak, YV2
Yee, R1
Schoen, FJ4
Levy, RJ3
Myers, DJ1
Nakaya, G1
Girardot, MN1
Christie, GW2
Abolhoda, A1
Yu, S1
Oyarzun, JR1
Allen, KR1
McCormick, JR1
Han, S1
Kemp, FW1
Bogden, JD1
Lu, Q1
Gabbay, S1
Chanda, J2
Kuribayashi, R2
Abe, T2
Walther, T1
Falk, V1
Autschbach, R1
Diegeler, A1
Rauch, T1
Weigl, C1
Günther, B1
van Son, JA1
Mohr, FW1
Hilbert, SL1
van Wachem, PB1
Brouwer, LA1
Zeeman, R1
Dijkstra, PJ1
Feijen, J1
Hendriks, M1
Cahalan, PT1
van Luyn, MJ1
Gross, JF1
Eberhardt, CE1
Boughner, DR1
Haldenby, M1
Hui, AJ1
Dunmore-Buyze, J1
Talman, EA1
Wan, WK1
Vesely, I2
Barber, JE1
Ratliff, NB1
Valente, M2
Minarini, M1
Ius, P1
Talenti, E2
Bortolotti, U2
Milano, A3
Thiene, G3
Barratt-Boyes, BG1
Mazzucco, A1
Laborde, F1
Gallix, P1
Boyd, J1
Jamieson, WR1
Janusz, MT1
Miyagishima, RT1
Munro, AI1
Gerein, AN1
Allen, P1
Burr, LH1
MacNab, J1
Chan, F1
Tyers, GF1
Starr, A1
Grunkemeier, GL1
Fessler, CL1
Golomb, G1
Smith, MS1
Linden, J1
Dixon, M1
Boughner, D1
Song, T1

Reviews

2 reviews available for glutaral and Prosthesis Durability

ArticleYear
Porcine aortic valve bioprostheses: morphologic and functional considerations.
    Journal of long-term effects of medical implants, 1992, Volume: 2, Issue:2-3

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcification, Physiologic; Connective Tissue; Cross-Linking R

1992
Tissue and mechanical valves: mutually advantageous interplay.
    Journal of cardiac surgery, 1988, Volume: 3, Issue:3 Suppl

    Topics: Age Factors; Anticoagulants; Bioprosthesis; Databases, Factual; Follow-Up Studies; Glutaral; Heart V

1988

Other Studies

37 other studies available for glutaral and Prosthesis Durability

ArticleYear
Bovine Pericardium of High Fibre Dispersion Has High Fatigue Life and Increased Collagen Content; Potentially an Untapped Source of Heart Valve Leaflet Tissue.
    Annals of biomedical engineering, 2021, Volume: 49, Issue:3

    Topics: Animals; Cattle; Collagen; Fixatives; Glutaral; Heart Valve Prosthesis; Pericardium; Prosthesis Fail

2021
Elimination of macrophages reduces glutaraldehyde-fixed porcine heart valve degeneration in mice subdermal model.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:1

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Cell Differentiation; Clodronic Acid; Cyt

2021
Modeling the response of exogenously crosslinked tissue to cyclic loading: The effects of permanent set.
    Journal of the mechanical behavior of biomedical materials, 2017, Volume: 75

    Topics: Bioprosthesis; Collagen; Extracellular Matrix; Glutaral; Heart Valve Prosthesis; Heart Valves; Model

2017
Postimplantation morphologic changes of glutaraldehyde-fixed porcine aortic roots and risk of aneurysm and rupture.
    The Journal of thoracic and cardiovascular surgery, 2009, Volume: 137, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Aortic Aneurysm; Aortic Rupture; Aortic Valve;

2009
Development of a new combined test setup for accelerated dynamic pH-controlled in vitro calcification of porcine heart valves.
    The International journal of artificial organs, 2009, Volume: 32, Issue:11

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Equipment Failure Analysis; Fixatives; Gl

2009
Transapical mitral valved stent implantation: a survival series in swine.
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 140, Issue:2

    Topics: Alloys; Animals; Bioprosthesis; Cardiac Catheterization; Echocardiography, Transesophageal; Fixative

2010
In vitro properties and performance of glutaraldehyde-crosslinked bovine pericardial bioprostheses treated with glutamic acid.
    Artificial organs, 2011, Volume: 35, Issue:5

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Equipme

2011
Nanocoating with titanium reduces iC3b- and granulocyte-activating immune response against glutaraldehyde-fixed bovine pericardium: a new technique to improve biologic heart valve prosthesis durability?
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:5

    Topics: Animals; Bioprosthesis; Cattle; Coated Materials, Biocompatible; Complement C3b; Fixatives; Glutaral

2012
Impairment of pericardial leaflet structure from balloon-expanded valved stents.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:6

    Topics: Animals; Aortic Valve; Bioprosthesis; Cardiac Catheterization; Cattle; Equipment Failure Analysis; F

2012
Changes in the mechanical properties of chemically treated bovine pericardium after a short uniaxial cyclic test.
    Artificial organs, 2013, Volume: 37, Issue:2

    Topics: Animals; Bioprosthesis; Cattle; Fixatives; Glutaral; Hardness; Hardness Tests; Heart Valve Prosthesi

2013
Glycosaminoglycan-degrading enzymes in porcine aortic heart valves: implications for bioprosthetic heart valve degeneration.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:2

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Chondroitinases and Chondroitin Lyases; D

2003
Degeneration of bioprosthetic heart valve cusp and wall tissues is initiated during tissue preparation: an ultrastructural study.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:2

    Topics: Animals; Aortic Valve; Bioprosthesis; Cell Death; Cross-Linking Reagents; Disease Models, Animal; Fi

2003
Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection.
    Circulation, 2006, Jul-25, Volume: 114, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Cell Movement; Glutaral; Graft Rejection; Guinea Pigs; Heart Val

2006
Stentless valves treated by the L-hydro process in the aortic position in sheep.
    Asian cardiovascular & thoracic annals, 2007, Volume: 15, Issue:5

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Equipment Failure Analysis; Female; Fixatives; Glu

2007
A comparison of failure modes of glutaraldehyde-treated versus antibiotic-preserved mitral valve allografts implanted in sheep.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bioprosthesis; Calcinosis; Calcium; Chordae Tendineae; Collagen; End

1995
Comparative analysis of glutaraldehyde-preserved porcine xenografts and fresh or glutaraldehyde-treated human aortic valves by holographic interferometry.
    Cardiovascular surgery (London, England), 1994, Volume: 2, Issue:6

    Topics: Aged; Aortic Valve; Bioprosthesis; Evaluation Studies as Topic; Glutaral; Heart Valve Prosthesis; Ho

1994
Biomechanical and structural properties of the explanted bioprosthetic valve leaflets.
    Journal of biomechanics, 1994, Volume: 27, Issue:1

    Topics: Adult; Animals; Aortic Valve; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Cattle; Child; Col

1994
[A modified composite graft: glutaraldehyde treatment of the vein and impervious covering on the composite site--an experimental and clinical study].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:9

    Topics: Aged; Aged, 80 and over; Animals; Aorta, Abdominal; Arterial Occlusive Diseases; Blood Vessel Prosth

1993
Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat subdermal model by FeCl3 and ethanehydroxydiphosphonate: preincubation and polymeric controlled release studies.
    Biomaterials, 1993, Volume: 14, Issue:9

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Chlorides; Delayed-Action Preparations; Disease Models,

1993
A comparison between glutaraldehyde and diepoxide-fixed stentless porcine aortic valves: biochemical and mechanical characterization and resistance to mineralization.
    The Journal of heart valve disease, 1995, Volume: 4 Suppl 1

    Topics: Animals; Aortic Valve; Biochemical Phenomena; Biochemistry; Biomechanical Phenomena; Bioprosthesis;

1995
No-react detoxification process: a superior anticalcification method for bioprostheses.
    The Annals of thoracic surgery, 1996, Volume: 62, Issue:6

    Topics: Animals; Aortic Valve; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Cell Survival; C

1996
Heparin in calcification prevention of porcine pericardial bioprostheses.
    Biomaterials, 1997, Volume: 18, Issue:16

    Topics: Animals; Anticoagulants; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Cross-Linking

1997
Prevention of calcification in glutaraldehyde-treated porcine aortic and pulmonary valves.
    The Annals of thoracic surgery, 1997, Volume: 64, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Glutaral; Heart Valve Prosthesis; Heparin; Male; Prosthesis Fail

1997
Pathologic findings in explanted clinical bioprosthetic valves fabricated from photooxidized bovine pericardium.
    The Journal of heart valve disease, 1998, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Animals; Aortic Valve; Aortic Valve Insufficiency; Bioprosthesis; Calcinosi

1998
Comparison of different anticalcification treatments for stentless bioprostheses.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:6 Suppl

    Topics: Aluminum; Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Disease Models, Animal; Durapat

1998
In vivo behavior of epoxy-crosslinked porcine heart valve cusps and walls.
    Journal of biomedical materials research, 2000, Volume: 53, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Carbodiimides; Coated Materials, Biocompatible; Cross-Linking Re

2000
Fatigue-induced changes to the biaxial mechanical properties of glutaraldehyde-fixed porcine aortic valve leaflets.
    Seminars in thoracic and cardiovascular surgery, 1999, Volume: 11, Issue:4 Suppl 1

    Topics: Aortic Valve; Biomechanical Phenomena; Bioprosthesis; Fixatives; Glutaral; Heart Valve Prosthesis; M

1999
The pericardial bioprosthesis: altered tissue shear properties following glutaraldehyde fixation.
    The Journal of heart valve disease, 2000, Volume: 9, Issue:6

    Topics: Biomechanical Phenomena; Bioprosthesis; Fixatives; Glutaral; Heart Valve Prosthesis; Humans; In Vitr

2000
Tissue damage and calcification may be independent mechanisms of bioprosthetic heart valve failure.
    The Journal of heart valve disease, 2001, Volume: 10, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Equipment Failure Analysis; Female; Fixatives; Glutaral; Graft S

2001
Durability of glutaraldehyde-fixed pericardial valve prostheses: clinical and animal experimental studies.
    The Journal of heart valve disease, 1992, Volume: 1, Issue:2

    Topics: Adult; Aged; Animals; Bioprosthesis; Calcinosis; Cattle; Fixatives; Glutaral; Heart Valve Diseases;

1992
Clinical experience with the zero-pressure-fixed Medtronic Intact bioprosthetic valve.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1992, Volume: 6 Suppl 1

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Bioprosthesis; Cause of Death; Echocardiography, Dopple

1992
Original expectations of the Hancock valve and 20 years of clinical reality.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1992, Volume: 6 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bioprosthesis; Child; Follow-Up Studies; Glutaral; Heart

1992
Glutaraldehyde-fixed bovine iliac veins used as bioprosthetic conduits: an experimental animal study.
    Journal of cardiac surgery, 1992, Volume: 7, Issue:2

    Topics: Animals; Bioprosthesis; Evaluation Studies as Topic; Glutaral; Heart Defects, Congenital; Heart Valv

1992
Prevention of calcification of glutaraldehyde pretreated bovine pericardium through controlled release polymeric implants: studies of Fe3+, Al3+, protamine sulphate and levamisole.
    Biomaterials, 1990, Volume: 11, Issue:9

    Topics: Aluminum; Animals; Calcium Phosphates; Cattle; Delayed-Action Preparations; Drug Implants; Ferric Co

1990
The Carpentier-Edwards standard porcine bioprosthesis: long-term evaluation of the high pressure glutaraldehyde fixed prosthesis.
    Journal of cardiac surgery, 1988, Volume: 3, Issue:3 Suppl

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bioprosthesis; British Columbia; Cause of Death; Child;

1988
The role of glutaraldehyde-induced cross-links in calcification of bovine pericardium used in cardiac valve bioprostheses.
    The American journal of pathology, 1987, Volume: 127, Issue:1

    Topics: Aldehydes; Animals; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Diffusion; Glutaral;

1987
Tissue buckling as a mechanism of bioprosthetic valve failure.
    The Annals of thoracic surgery, 1988, Volume: 46, Issue:3

    Topics: Animals; Aortic Valve; Bioprosthesis; Elastic Tissue; Glutaral; Heart Valve Prosthesis; Prosthesis D

1988