Page last updated: 2024-10-28

glutaral and Hay Fever

glutaral has been researched along with Hay Fever in 32 studies

Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.

Research Excerpts

ExcerptRelevanceReference
"12 patients suffering from grass pollen hay fever were treated for 14 weeks pre- and co-seasonally by intranasal self-administration of an aqueous solution of a glutaraldehyde-treated timothy grass pollen allergen."9.04Use of glutaraldehyde-modified timothy grass pollen extract in nasal hyposensitisation treatment of hay fever. ( Deuschl, H; Johansson, SG; Zetterström, O, 1979)
"One hundred patients with hay fever were treated in 1974/5 with a glutaraldehyde-pollen-tyrosine adsorbate, the response to treatment being assessed at the end of the hay fever season by direct questioning of the patient and examination of a daily record card."7.65A trial of hyposensitization in 1974/5 in the treatment of hay fever using glutaraldehyde-pollen-tyrosine adsorbate. ( Miller, AC, 1976)
"12 patients suffering from grass pollen hay fever were treated for 14 weeks pre- and co-seasonally by intranasal self-administration of an aqueous solution of a glutaraldehyde-treated timothy grass pollen allergen."5.04Use of glutaraldehyde-modified timothy grass pollen extract in nasal hyposensitisation treatment of hay fever. ( Deuschl, H; Johansson, SG; Zetterström, O, 1979)
"A direct comparison was made in 112 hay fever patients of hyposensitization treatment with glutaraldehyde-pollen-tyrosine adsorbate (Pollinex) and with alum-precipitated pyridine extract (Alavac-P) which is an accepted form of treatment, its efficacy having been shown by a comparative trial against a placebo preparation."5.04A comparative trial of hyposensitization in 1973 in the treatment of hay fever using Pollinex and Alavac-P. ( Miller, AC, 1976)
"One hundred patients with hay fever were treated in 1974/5 with a glutaraldehyde-pollen-tyrosine adsorbate, the response to treatment being assessed at the end of the hay fever season by direct questioning of the patient and examination of a daily record card."3.65A trial of hyposensitization in 1974/5 in the treatment of hay fever using glutaraldehyde-pollen-tyrosine adsorbate. ( Miller, AC, 1976)
" Dose-response skin tests were performed at baseline and at the end of the trial."2.72Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule. ( Colás, C; Lezaun, A; Monzón, S; Venturini, M, 2006)
" Dose-response skin prick test with each allergen extract was conducted at baseline and at the end of the study."2.71Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life. ( Alvarez-Cuesta, E; Aragoneses-Gilsanz, E; Berges-Gimeno, P; Cuesta-Herranz, J; Gonzalez-Mancebo, E; Martín-Garcia, C, 2005)
"In 27 patients with pollen allergy the nasal lavage was performed before, during and after pollen season."2.68[Characteristics of hay fever during pollen season with regard to the influence of specific immunotherapy. I. Clinical course and biochemical changes in nasal lavage]. ( Grzegorczyk, J; Kowalski, M; Rozniecka, M; Rozniecki, J; Sliwińska-Kowalska, M; Wojciechowska, B, 1995)
" The SDV treatment induced a more pronounced IgG antibody response both in patients and in guinea-pigs receiving the clinical dosage schedule."2.64A comparative study of an aqueous grass pollen extract and glutaraldehyde-treated grass pollen-tyrosine adsorbate in the treatment of pollenosis. ( Verstraeten, JM; Wheeler, AW, 1978)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199018 (56.25)18.7374
1990's9 (28.13)18.2507
2000's4 (12.50)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rauber, MM1
Wu, HK1
Adams, B1
Pickert, J1
Bohle, B1
Shamji, MH1
Pfützner, W1
Möbs, C1
Alvarez-Cuesta, E1
Aragoneses-Gilsanz, E1
Martín-Garcia, C1
Berges-Gimeno, P1
Gonzalez-Mancebo, E1
Cuesta-Herranz, J1
Colás, C1
Monzón, S1
Venturini, M1
Lezaun, A1
Asturias, JA1
Ferrer, A1
Arilla, MC1
Andreu, C1
Madariaga, B1
Martínez, A1
Subiza, J1
Feliú, A1
Subiza, JL1
Uhlig, J1
Fernández-Caldas, E1
Fal, W1
Brańska, B1
Latoś, T1
Galary, E1
Ligeziński, A1
Metzger, WJ2
Dorminey, HC1
Richerson, HB1
Weiler, JM1
Donnelly, A1
Moran, D1
Small, P2
Shapiro, M1
Medrala, W1
Małolepszy, J2
Wolańczyk-Medrala, A1
Wrzyszcz, M1
Rybakiewicz, R1
Litwa, M1
Rozniecka, M2
Kowalski, M1
Grzegorczyk, J2
Wojciechowska, B2
Sliwińska-Kowalska, M2
Rozniecki, J2
Kowałski, ML1
Boznański, A1
Pirogowicz, I1
Widerska, A1
Hebrowska, A1
Foucard, T1
Johansson, SG3
Verstraeten, JM1
Wheeler, AW3
Gniazdowski, R1
Deuschl, H1
Zetterström, O1
Weisnagel, J1
Jarisch, R1
Cockcroft, DW1
Cuff, MT1
Tarlo, SM1
Dolovich, J1
Hargreave, FE2
Patterson, R1
Zeiss, R1
Irons, JS1
Pruzansky, JJ1
Suszko, IM1
Levitz, D1
Miller, AC3
Rogala, B1
Jarzab, J1
Karawajczyk, M1
Jawor, B1
Rogala, E1
Bonifazi, F1
Antonicelli, L1
Bilò, MB1
Pucci, S1
Taylor, IH1
Youlten, LJ2
Resta, O1
Carnimeo, N1
Foschino, MP1
Taylor, I1
Kruszewski, J1
Juniper, EF1
Kline, PA1
Ramsdale, EH1
Ko, HS1
Chen, SJ1
Jaworska, E1
Zak-Nejmark, T1
Nadobna, G1
Ossos, M1
Liebhart, J1
Mullan, N1
Overell, BG1
Tees, EC1
Wheeler, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blinded, Placebo-Controlled, Prospective, Multicenter CT to Evaluate Efficacy and Safety of Subcutaneous Immunotherapy in Subjects With Rhinitis With/Without Mild to Moderate Asthma Sensitized to Olive and Grass Pollen[NCT04891237]Phase 3180 participants (Anticipated)Interventional2021-06-14Recruiting
Prospective, Randomized, Placebo-controlled, Multi-center Trial Comparing the Efficacy and Safety of Subcutaneous Immunotherapy With a Mixture of Grasses and Mites at Adequate Doses Versus Monotherapy, for the Treatment of Allergy[NCT04874714]Phase 318 participants (Actual)Interventional2021-04-30Terminated (stopped due to Due to the low recruitment rate since the start of the trial)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

16 trials available for glutaral and Hay Fever

ArticleYear
Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Asthma; Cross-Linking Reagents; Dose-Response Relationship, Immunologic; Double-B

2005
Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule.
    The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:4

    Topics: Adolescent; Adult; Allergens; Asthma; Conjunctivitis, Allergic; Desensitization, Immunologic; Double

2006
Tolerance and immunological changes of chemically modified allergen vaccine of Parietaria judaica in accelerated schedules.
    Clinical and experimental immunology, 2007, Volume: 147, Issue:3

    Topics: Adolescent; Adult; Aged; Allergens; Antigens, Plant; Chemical Phenomena; Chemistry, Physical; Desens

2007
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:6

    Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration

2008
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:6

    Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration

2008
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:6

    Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration

2008
Cluster immunotherapy with a glutaraldehyde-modified mixture of grasses results in an improvement in specific nasal provocation tests in less than 2.5 months of treatment.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:6

    Topics: Adult; Allergens; Analysis of Variance; Dactylis; Desensitization, Immunologic; Drug Administration

2008
Clinical and immunologic evaluation of glutaraldehyde-modified tyrosine-adsorbed short ragweed extract: a double-blind, placebo-controlled trial.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:6

    Topics: Aldehydes; Antibody Specificity; Antigen-Antibody Complex; Binding, Competitive; Clinical Trials as

1981
[Spontaneous histamine release by basophils and bronchial hyperreactivity in patients with hay fever].
    Pneumonologia i alergologia polska, 1995, Volume: 63, Issue:3-4

    Topics: Allergens; Antigens, Plant; Basophils; Bronchial Hyperreactivity; Drug Combinations; Glutaral; Hista

1995
[Characteristics of hay fever during pollen season with regard to the influence of specific immunotherapy. I. Clinical course and biochemical changes in nasal lavage].
    Pneumonologia i alergologia polska, 1995, Volume: 63, Issue:3-4

    Topics: Adult; Albumins; Allergens; Antigens, Plant; Drug Combinations; Female; Glutaral; Humans; Immunother

1995
[Course of hay fever during the pollen season with respect to the effect of specific immunotherapy. II. Cytologic changes and chemotactic activity in nasal lavage].
    Pneumonologia i alergologia polska, 1995, Volume: 63, Issue:3-4

    Topics: Adult; Allergens; Antigens, Plant; Chemotaxis, Leukocyte; Drug Combinations; Eosinophils; Female; Gl

1995
A comparative study of an aqueous grass pollen extract and glutaraldehyde-treated grass pollen-tyrosine adsorbate in the treatment of pollenosis.
    Clinical allergy, 1978, Volume: 8, Issue:5

    Topics: Adult; Animals; Antigen-Antibody Complex; Female; Glutaral; Guinea Pigs; Humans; Immunoglobulin E; I

1978
Use of glutaraldehyde-modified timothy grass pollen extract in nasal hyposensitisation treatment of hay fever.
    International archives of allergy and applied immunology, 1979, Volume: 60, Issue:4

    Topics: Aldehydes; Allergens; Cell Extracts; Desensitization, Immunologic; Glutaral; Humans; Immunoglobulin

1979
Allergen injection therapy with glutaraldehyde-modified--ragweed pollen-tyrosine adsorbate. A double-blind trial.
    The Journal of allergy and clinical immunology, 1977, Volume: 60, Issue:1

    Topics: Aldehydes; Allergens; Antigen-Antibody Complex; Clinical Trials as Topic; Glutaral; Humans; Immunogl

1977
A comparative trial of hyposensitization in 1973 in the treatment of hay fever using Pollinex and Alavac-P.
    Clinical allergy, 1976, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Aldehydes; Alum Compounds; Antigens, Plant; Child; Clinical Trials as Topic; Dese

1976
Hyposensitization therapy of Parietaria-sensitive patients with a tyrosine adsorbed allergoid, Pollinex Parietaria (Bencard Parietaria).
    Journal of investigational allergology & clinical immunology, 1991, Volume: 1, Issue:1

    Topics: Adult; Allergens; Allergoids; Antigens, Plant; Desensitization, Immunologic; Drug Combinations; Fema

1991
Pollinex Parietaria (Bencard Parietaria), a new allergoid for treatment of patients sensitive to Parietaria pollen.
    Journal of investigational allergology & clinical immunology, 1991, Volume: 1, Issue:2

    Topics: Adult; Allergens; Allergoids; Antigens, Plant; Desensitization, Immunologic; Drug Combinations; Fema

1991
Comparison of the efficacy and side effects of aqueous steroid nasal spray (budesonide) and allergen-injection therapy (Pollinex-R) in the treatment of seasonal allergic rhinoconjunctivitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 85, Issue:3

    Topics: Aldehydes; Allergens; Antigens, Plant; Budesonide; Conjunctivitis, Allergic; Desensitization, Immuno

1990
Glutaraldehyde-pollen-tyrosine: clinical and immunological studies.
    Clinical allergy, 1974, Volume: 4, Issue:3

    Topics: Aldehydes; Antibodies; Glutaral; Humans; Immunoglobulin E; Immunoglobulin G; Plant Extracts; Plants;

1974

Other Studies

16 other studies available for glutaral and Hay Fever

ArticleYear
Birch pollen allergen-specific immunotherapy with glutaraldehyde-modified allergoid induces IL-10 secretion and protective antibody responses.
    Allergy, 2019, Volume: 74, Issue:8

    Topics: Allergens; Allergoids; Antibody Formation; Antigens, Plant; Betula; Glutaral; Humans; Immunity, Cell

2019
[Histamine level of basophils in children with pollinosis treated with pollinex].
    Pediatria polska, 1984, Volume: 59, Issue:3

    Topics: Adolescent; Aldehydes; Allergens; Antigens, Plant; Basophils; Child; Drug Combinations; Female; Glut

1984
[Radioimmunologic tests in specific immunotherapy of atopic rhinitis].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1984, Dec-01, Volume: 37, Issue:23

    Topics: Adolescent; Adult; Aldehydes; Allergens; Antigens; Antigens, Dermatophagoides; Antigens, Plant; Dese

1984
Immunotherapy with glutaraldehyde treated tyrosine adsorbed grass pollen in the treatment of allergic rhinitis.
    Annals of allergy, 1981, Volume: 47, Issue:6

    Topics: Aldehydes; Allergens; Antigen-Antibody Complex; Antigens, Plant; Complement System Proteins; Desensi

1981
Modified ragweed extract.
    The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:6

    Topics: Adult; Aldehydes; Allergens; Anaphylaxis; Antigens, Plant; Drug Combinations; Female; Glutaral; Huma

1982
[Effect of immunotherapy on selected immunologic indices in children with pollinosis].
    Pediatria polska, 1996, Volume: 71, Issue:1

    Topics: Adolescent; Allergens; Antigens, Plant; CD4-CD8 Ratio; Child; Drug Combinations; Female; Glutaral; H

1996
Immunological studies in vitro and in vivo of children with pollenosis given immunotherapy with an aqueous and a glutaraldehyde-treated tyrosine-absorbed grass pollen extract.
    Clinical allergy, 1976, Volume: 6, Issue:5

    Topics: Adsorption; Child; Desensitization, Immunologic; Glutaral; Histamine Release; Humans; Immunoglobulin

1976
[Treatment of hay fever with "Pollinex"].
    Otolaryngologia polska = The Polish otolaryngology, 1978, Volume: 32, Issue:4

    Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aldehydes; Allergens; Antigens, Plant; Desensitization,

1978
[A new desensitization agent in the treatment of ragweed-induced seasonal allergic rhinitis (hay fever) in children: MRTA (modified ragweed tyrosine adsorbate)].
    L'union medicale du Canada, 1979, Volume: 108, Issue:6

    Topics: Aldehydes; Child; Desensitization, Immunologic; Double-Blind Method; Drug Combinations; Drug Evaluat

1979
[Glutarladehyde-pollen-tyrosine hyposensitization. Course control of therapy using RIST and RAST].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1977, Volume: 28, Issue:4

    Topics: Antibodies; Desensitization, Immunologic; Drug Evaluation; Follow-Up Studies; Glutaral; Humans; Immu

1977
Comparison of polymerized and unpolymerized antigen E for immunotherapy of ragweed allergy.
    The New England journal of medicine, 1976, Nov-18, Volume: 295, Issue:21

    Topics: Adult; Allergens; Antibodies; Desensitization, Immunologic; Female; Glutaral; Humans; Immunity, Cell

1976
A trial of hyposensitization in 1974/5 in the treatment of hay fever using glutaraldehyde-pollen-tyrosine adsorbate.
    Clinical allergy, 1976, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Aldehydes; Antigen-Antibody Complex; Child; Desensitization, Immunologic; Female;

1976
Effect of specific immunotherapy on IgE immune complexes in seasonal allergic rhinitis.
    Pneumonologia i alergologia polska, 1992, Volume: 60 Suppl 1

    Topics: Adolescent; Adult; Allergens; Antigen-Antibody Complex; Antigens, Plant; Desensitization, Immunologi

1992
[Changes in allergen-specific IgG-4 during desensitization of patients with hay fever and those sensitized to housedust allergens].
    Pneumonologia i alergologia polska, 1991, Volume: 59 Suppl 1

    Topics: Adult; Air Pollutants; Air Pollution, Indoor; Allergens; Animals; Antigens, Dermatophagoides; Antige

1991
IgG and IgE antibody response following Pollinex-R immunotherapy.
    Annals of allergy, 1987, Volume: 59, Issue:6

    Topics: Adolescent; Adult; Aged; Aldehydes; Allergens; Antigens, Plant; Child; Desensitization, Immunologic;

1987
The effect of immunotherapy in hayfever patients on histamine binding capacity of blood serum proteins.
    Archivum immunologiae et therapiae experimentalis, 1987, Volume: 35, Issue:5

    Topics: Adult; Aldehydes; Allergens; Antigens, Plant; Blood Proteins; Desensitization, Immunologic; Drug Com

1987