Page last updated: 2024-10-28

glutaral and Calcinosis

glutaral has been researched along with Calcinosis in 199 studies

Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.

Calcinosis: Pathologic deposition of calcium salts in tissues.

Research Excerpts

ExcerptRelevanceReference
"Recent studies have suggested that pathologic calcification is regulated by inductive and inhibitory factors, similar to the physiologic mineralization of bone."2.43Calcification of tissue heart valve substitutes: progress toward understanding and prevention. ( Levy, RJ; Schoen, FJ, 2005)
"Glutaraldehyde-treated tissue is stable against chemical and enzymatic degradation; however, its calcification and cytotoxicity are severe."2.42[Using chemical methods to crosslink xenogeneic heart valves: the progress of bioprosthetic heart valves]. ( Chang, R; Cui, JW; Hu, SS; Lin, L; Tang, YW; Zhang, FS; Zhou, JY, 2003)
"Genipin fixation is a novel alternative to conventional GA fixation in vitro material assessment and in vivo anticalcification effect."1.38Anticalcification effects of decellularization, solvent, and detoxification treatment for genipin and glutaraldehyde fixation of bovine pericardium. ( Choi, SY; Kim, SH; Kim, YJ; Lim, HG, 2012)
"Glutaraldehyde-treated bioprosthetic heart valves are commonly used for replacement of diseased heart valves."1.37Degenerative processes in bioprosthetic mitral valves in juvenile pigs. ( Funder, JA; Hasenkam, JM; Honge, JL; Kronborg, MB; Pedersen, TB, 2011)
"Steroid treatment decreased inflammation and antibody rise in the xenogeneic groups (P<0."1.33Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection. ( Churchill, TA; Korbutt, GS; Koshal, A; Manji, RA; Nijjar, NK; Rajotte, RV; Rayner, DC; Ross, DB; Zhu, LF, 2006)
"Pathologic calcification is the leading cause of the clinical failure of glutaraldehyde-fixed bovine pericardium used in bioprosthetic valves."1.32Hyaluronic acid grafting mitigates calcification of glutaraldehyde-fixed bovine pericardium. ( Giachelli, CM; Hahn, SK; Hoffman, AS; Ohri, R; Stayton, PS, 2004)
"Pathologic calcification is thought to be the main cause of failure in the present generation tissue valves fabricated from glutaraldehyde pretreated bovine pericardium (BP)."1.31The anticalcification effect of polyethylene glycol-immobilized on hexamethylene diisocyanate treated pericardium. ( Chandy, T; Sharma, CP; Vasudev, SC, 2000)
"Glutaraldehyde (GA)-pretreated porcine aortic valves are generally used as a bioprosthetic valve, but gradual calcification of the leaflets often occurs."1.31Calcification of leaflets from porcine aortic valves crosslinked by ultraviolet irradiation. ( Cho, BK; Hwang, YS; Park, JC; Suh, H, 2000)
"Glutaraldehyde treatment of collagen biomaterials promotes calcification, poor host-tissue incorporation, and ultimately mechanical failure of bioprotheses."1.30Calcification potential of small intestinal submucosa in a rat subcutaneous model. ( Geddes, LA; Hiles, MC; Lantz, GC; Martin, BR; Owen, TJ; VanVleet, J, 1997)
"Glutaraldehyde treatment (0."1.30Does glutaraldehyde induce calcification of bioprosthetic tissues? ( Chachques, JC; Fabiani, JN; Lajos, PS; Latrémouille, C; Shen, M; Vincentelli, A; Zegdi, R, 1998)
"Heat treatment of glutaraldehyde-treated bioprostheses significantly mitigated calcification in both subcutaneous and mitral position."1.30Heat treatment mitigates calcification of valvular bioprostheses. ( Carpentier, AF; Carpentier, SM; Chen, L; Fornes, P; Martinet, B; Quintero, LJ; Shen, M; Witzel, TH, 1998)
"Glutaraldehyde-treated porcine aortic valve xenografts frequently fail due to calcification."1.30Role of glutaraldehyde in calcification of porcine aortic valve fibroblasts. ( Battarbee, HD; Herrera, GA; Kim, KM, 1999)
"Glutaraldehyde pretreatment did not affect calcification (Ca(2+) = 89."1.30Elastin calcification and its prevention with aluminum chloride pretreatment. ( Levy, RJ; Ogle, M; Schoen, FJ; Vyavahare, N, 1999)
"Glutaraldehyde treatment of the anterior leaflet caused thickening of the cusp and chordae associated with partial devitalization of its core tissue, partial loss of endothelium and intense fibrocellular reaction with abundant elastic fibers without altering its functional integrity."1.29In situ mitral valve stabilization with glutaraldehyde. ( Ali, ML; Becker, A; Duran, CM; Kumar, SP; Prabhakar, G, 1995)
"Thus glutaraldehyde-treated allografts failed because of extensive calcification, whereas antibiotic-preserved allografts underwent deterioration of connective tissue and infiltration by inflammatory cells."1.29A comparison of failure modes of glutaraldehyde-treated versus antibiotic-preserved mitral valve allografts implanted in sheep. ( Ferrans, VJ; Jones, M; Tamura, K; Yamada, I, 1995)
"glutaraldehyde-treated autograft Sprague-Dawley (SD) rat skin, xenograft Swiss-Webster (SW) mouse skin, and saline-treated autograft (control) were subcutaneously implanted in ten weanling SD rats, and retrieved after 70 days."1.29Bioprosthetic cardiac valve degeneration: role of inflammatory and immune reactions. ( Blau, S; Factor, SM; Frater, RW; Gong, G; Lyman, WD; Seifter, E, 1993)
"Glutaraldehyde treatment significantly decreased the medial thickness in both iso- and allografts (P < 0."1.29Effects of glutaraldehyde on experimental arterial iso- and allografts in rats. ( Dumont, CE; Guettier, C; Michel, JB; Plissonnier, D, 1993)
"Glutaraldehyde pretreatment of bioprosthetic heart valves is the major pathogenic factor in their calcific degeneration."1.29No-react detoxification process: a superior anticalcification method for bioprostheses. ( Abolhoda, A; Allen, KR; Bogden, JD; Gabbay, S; Han, S; Kemp, FW; Lu, Q; McCormick, JR; Oyarzun, JR; Yu, S, 1996)
"Treatment of glutaraldehyde-fixed pericardium with L-glutamic acid and storage in bacteriostatic preservatives (paraben) stably antagonizes free, reactive aldehyde groups within the fixed bioprosthetic heart valve tissue."1.28Improved biocompatibility of bioprosthetic heart valves by L-glutamic acid treatment. ( Böck, P; Eybl, E; Grabenwöger, M; Grimm, M; Moritz, A; Müller, MM; Wolner, E, 1992)
"A glutaraldehyde-treated sponge was completely calcified after 15 days, and calcified nodules persisted after 90 days."1.28Inhibition of calcification in vivo by acyl azide cross-linking of a collagen-glycosaminoglycan sponge. ( Anselme, K; Herbage, D; Petite, H, 1992)
"Glutaraldehyde pretreatment restricted reaction with other modifying agents, but, as a post-fixation treatment, improved the thermal stability of other agents."1.28Chemical modification of bovine pericardium and its effect on calcification in the rat subdermal model. ( Bernacca, GM; Dimitri, WR; Fisher, AC; Mackay, TG; Wheatley, DJ, 1992)
"Formaldehyde-pretreated implants calcified more extensively (Ca2+ = 87."1.27Calcification of subcutaneously implanted type I collagen sponges. Effects of formaldehyde and glutaraldehyde pretreatments. ( Hawley, MA; Levy, RJ; Lund, SA; Nichols, J; Schoen, FJ; Sherman, FS, 1986)

Research

Studies (199)

TimeframeStudies, this research(%)All Research%
pre-199016 (8.04)18.7374
1990's74 (37.19)18.2507
2000's51 (25.63)29.6817
2010's40 (20.10)24.3611
2020's18 (9.05)2.80

Authors

AuthorsStudies
Botes, L1
Laker, L1
Dohmen, PM2
van den Heever, JJ1
Jordaan, CJ1
Lewies, A1
Smit, FE1
Kaneko, S1
Isoda, S1
Aoyama, T1
Goda, M1
Yasuda, S1
Shibuya, T1
Matsumura, M1
Mitsui, H1
Okudela, K1
Suzuki, S1
Machida, D1
Masuda, M1
Liang, X1
Zheng, C3
Ding, K2
Huang, X2
Zhang, S2
Lei, Y5
Yu, K1
Wang, Y11
Hu, M4
Peng, X3
Yue, L1
Ding, H1
Yu, X4
Wan, C2
Cheng, C2
Zakharchenko, A1
Rock, CA1
Thomas, TE1
Keeney, S1
Hall, EJ1
Takano, H1
Krieger, AM1
Ferrari, G1
Levy, RJ18
Shi, S2
Lei, N1
Wei, Q1
Yang, L2
Melder, RJ1
Naso, F1
Nicotra, F1
Russo, L1
Vesely, I3
Tuladhar, SR1
Calafiore, AM1
Zilla, P14
Gandaglia, A1
Korossis, S2
Yu, T3
Pu, H2
Chen, X3
Kong, Q1
Chen, C1
Li, G3
Jiang, Q3
Guo, Y2
Kuang, D1
Zhuravleva, IY2
Karpova, EV1
Dokuchaeva, AA1
Titov, AT1
Timchenko, TP2
Vasilieva, MB1
Wu, H1
Huang, K1
Chen, N1
Qin, Y1
Wang, J1
Luo, R1
Pu, X1
Chang, J2
Yu, L1
Lei, J1
Liu, X2
Li, C1
Zheng, Y1
Chen, H1
Yang, F1
He, H1
Xu, L2
Jin, L2
Guo, G3
Liu, Z1
Xie, F1
Li, F1
Dong, N1
Arruda, MB1
Aguiar, LD1
Marques, SRB1
Cavalcanti, LRP1
Sá, MPBO1
Park, CS1
Kim, YJ8
Lee, JR1
Lim, HG6
Chang, JE1
Jeong, S3
Kwon, N1
Halfwerk, FR1
Rouwkema, J1
Gossen, JA1
Grandjean, JG1
Nichay, NR1
Kulyabin, YY1
Voitov, AV1
Kuznetsova, EV1
Soynov, IA1
Zubritskiy, AV1
Bogachev-Prokophiev, AV1
Karaskov, AM1
Meuris, B4
De Praetere, H1
Strasly, M1
Trabucco, P1
Lai, JC1
Verbrugghe, P1
Herijgers, P3
Hendriks, M7
Everaerts, F3
Verhoeven, M2
Human, P12
Jin, W2
Chen, L2
Xia, Y1
Agathos, EA1
Tomos, PI1
Kostomitsopoulos, N1
Koutsoukos, PG2
Badria, A1
Koutsoukos, P1
Mavrilas, D2
Liu, M1
Taniguchi, FP1
Maizato, MJ2
Ambar, RF1
Pitombo, RN2
Leiner, AA1
Moreira, LF1
Cestari, IA1
Stolf, NA1
Barros, JA1
Filippin-Monteiro, FB1
de Oliveira, EM1
Campa, A1
Catalani, LH1
Pitombo, Rde N1
Polakiewicz, B1
Zhu, D1
Wang, X1
Liu, T1
Evans, CF1
DeFilippi, CR1
Shang, E1
Griffith, BP1
Gammie, JS1
Neethling, W1
Brizard, C1
Firth, L1
Glancy, R5
Sato, M1
Hiramatsu, Y1
Matsushita, S1
Sato, S1
Watanabe, Y1
Sakakibara, Y1
Brizard, CP1
Brink, J1
Horton, SB1
Edwards, GA1
Galati, JC1
Neethling, WM5
Choi, SY3
Shin, JS1
Park, CG1
Kim, GB1
Fukunaga, N1
Matsuo, T1
Saji, Y1
Imai, Y1
Koyama, T1
Baird, CW1
Myers, PO1
Piekarski, B1
Borisuk, M1
Majeed, A1
Emani, SM1
Sanders, SP1
Nathan, M1
Del Nido, PJ1
Sung Jeong, W1
Jin Kim, Y1
Jung, S1
Ryul Lee, J1
Lee, C3
Lee, CH1
Tam, H1
Zhang, W1
Infante, D1
Parchment, N1
Sacks, M1
Vyavahare, N4
Pettenazzo, E2
Valente, M4
Thiene, G4
Wang, D2
Jiang, H2
Li, J1
Zhou, JY2
Hu, SS2
Zhai, W1
Lü, X1
Wang, Z1
Zhou, J1
Hu, S1
Kriegs, M1
Kanellopoulou, D1
Glasmacher, B1
Mangold, A1
Ankersmit, HJ1
Kim, SH5
Choi, SH1
Chan, KM1
Rahman-Haley, S1
Mittal, TK1
Gavino, JA1
Dreyfus, GD1
Honge, JL2
Funder, J1
Hansen, E1
Konertz, W1
Hasenkam, JM2
McGregor, CG1
Carpentier, A2
Lila, N1
Logan, JS1
Byrne, GW1
Hodge, AJ4
Chang, HW1
Kim, KH1
Umashankar, PR1
Arun, T1
Kumari, TV1
Funder, JA1
Pedersen, TB1
Kronborg, MB1
Braile, MC1
Carnevalli, NC1
Goissis, G1
Ramirez, VA1
Braile, DM1
Sinha, P1
Zurakowski, D1
Kumar, TK1
He, D1
Rossi, C1
Jonas, RA1
Leong, J1
Munnelly, A1
Liberio, B1
Cochrane, L1
Ahn, H1
Love, CS1
Trantina-Yates, AE1
Ogle, MF1
Kelly, SJ1
Bianco, RW2
Simionescu, DT2
Lovekamp, JJ1
Vyavahare, NR4
Phillips, R2
Moore, MA4
Flameng, W3
Bailey, MT1
Pillarisetti, S1
Xiao, H1
Ortolani, F1
Petrelli, L1
Nori, SL1
Gerosa, G1
Spina, M1
Marchini, M1
Lin, L1
Tang, YW1
Chang, R1
Cui, JW1
Zhang, FS1
Pathak, CP1
Adams, AK2
Simpson, T1
Phillips, RE2
Connolly, JM1
Alferiev, I1
Kronsteiner, A1
Lu, Z1
Ohri, R1
Hahn, SK1
Hoffman, AS1
Stayton, PS1
Giachelli, CM1
Isenburg, JC1
Bezuidenhout, D6
Schoen, FJ17
Nina, VJ1
Pomerantzeff, PM1
Casagrande, IS1
Cheung, DT3
Brandão, CM1
Oliveira, SA1
Torrianni, M3
Gillissen, M1
Feijen, J3
Manji, RA1
Zhu, LF1
Nijjar, NK1
Rayner, DC1
Korbutt, GS1
Churchill, TA1
Rajotte, RV1
Koshal, A1
Ross, DB1
Clode, P1
Santos, PC1
Gerola, LR1
Casagrande, I1
Buffolo, E1
Pires, MD1
Canzian, M1
Higa, OZ1
Leirner, AA1
Hellberg, K1
Ruschewski, W1
de Vivie, ER1
Thubrikar, MJ1
Nolan, SP1
Deck, JD1
Aouad, J1
Levitt, LC1
Thandroyen, FT1
Whitton, IN1
Pirie, D1
Rogers, MA1
Mitha, AS1
Bruck, SD1
Bortolotti, U2
Milano, A2
Mazzucco, A1
Valfre, C1
Fasoli, G1
Gallucci, V1
Camilleri, JP1
Pornin, B1
Kumar, SP2
Prabhakar, G2
Kumar, M1
Kumar, N1
Shahid, M1
Ali, ML2
Becker, A2
Duran, CM2
Tamura, K1
Jones, M1
Yamada, I1
Ferrans, VJ1
Chanda, J11
Liao, K3
Frater, RW5
LaPietra, A1
Ciuffo, G1
Ilardi, CF1
Seifter, E4
Gong, G2
Lyman, WD1
Factor, SM3
Blau, S1
Rao, SB2
Mohanty, M3
Lal, AV1
Muraleedharan, CV1
Bhuvaneshwar, GS1
Valiathan, MS2
Chen, W2
Kim, JD1
Jorge-Herrero, E3
Fernández, P2
de la Torre, N1
Escudero, C2
García-Páez, JM2
Buján, J1
Castillo-Olivares, JL2
Purinya, B1
Kasyanov, V1
Volkolakov, J1
Latsis, R1
Tetere, G1
Hirsch, D5
Drader, J2
Thomas, TJ1
Levy, JT1
Tan, WM1
Loke, WK1
Tan, BL1
Wee, A1
Khor, E1
Goh, KS1
Hoffman, D1
Macaluso, F1
Pathak, YV1
Yee, R1
Flomenbaum, MA1
Dumont, CE1
Plissonnier, D1
Guettier, C1
Michel, JB1
Myers, DJ1
Nakaya, G1
Girardot, MN2
Christie, GW1
Chandy, T8
John, A1
Sivakumar, R1
Sharma, CP8
Abolhoda, A2
Yu, S2
Oyarzun, JR2
McCormick, JR2
Bogden, JD2
Gabbay, S2
Kuribayashi, R8
Abe, T8
Grabenwöger, M4
Sider, J1
Fitzal, F2
Zelenka, C1
Windberger, U1
Grimm, M4
Moritz, A2
Böck, P4
Wolner, E4
Mrachek, J1
Witson, J1
Silvestrini, G1
Zini, N1
Sabatelli, P1
Mocetti, P1
Maraldi, NM1
Bonucci, E1
Vardaxis, NJ1
Boon, ME1
Ruijgrok, JM1
Girardot, JM1
Allen, KR1
Han, S1
Kemp, FW1
Lu, Q1
Lerner, E2
Baskin, JZ2
Bianco, R1
Kruth, HS1
Zand, R2
Sekine, S1
Shibata, Y1
Yamagishi, I1
Vasudev, SC9
Nimni, ME5
Myers, D1
Ertl, D1
Han, B1
Owen, TJ1
Lantz, GC1
Hiles, MC1
VanVleet, J1
Martin, BR1
Geddes, LA1
Weissenstein, C5
Bracher, M1
Zhang, Y1
Koen, W1
von Oppell, U2
Fullard, L1
Trescony, P1
Meinhart, J1
Gorlitzer, M1
Santin, M1
Motta, A1
Cannas, M1
Schmidberger, A1
Laufer, G1
Bergmeister, H1
Molin, GM1
Martignago, F1
De Giorgi, G1
Gatti, AM1
Giaretta, A1
Pasquino, E1
Talenti, E2
Rinaldi, S1
Rao, GH1
Aravind, S1
Paul, W1
McIlroy, BK1
Walley, VM1
Hendry, PJ1
Walther, T2
Falk, V2
Autschbach, R2
Diegeler, A2
Rauch, T2
Weigl, C2
Günther, B1
van Son, JA1
Mohr, FW2
Vincentelli, A1
Latrémouille, C1
Zegdi, R1
Shen, M2
Lajos, PS1
Chachques, JC1
Fabiani, JN1
Carpentier, SM1
Fornes, P1
Martinet, B1
Quintero, LJ1
Witzel, TH1
Carpentier, AF1
Kim, KM2
Herrera, GA1
Battarbee, HD1
Shen, SH1
Sung, HW1
Tu, R1
Hata, C1
Lin, D1
Noishiki, Y2
Quijano, RC1
Gummert, J1
Milo, S1
Adler, Z1
Bar-El, Y1
Kertsman, V1
Sawaed, S1
Lorber, A1
Reisner, S1
Mako, WJ1
Shah, A1
Ogle, M1
van Wachem, PB2
Brouwer, LA2
Zeeman, R2
Dijkstra, PJ2
Cahalan, PT2
van Luyn, MJ2
Umasankar, PR1
Moses, LR1
Suh, H2
Hwang, YS1
Park, JC2
Cho, BK1
Schmidt, CE1
Baier, JM1
Lee, WK1
Park, KD1
Kim, YH1
Lee, JE1
Sun, K1
Baek, MJ1
Kim, HM1
Dower, T1
von Oppell, UO1
Mirzaie, M1
Meyer, T1
Saalmüller, A1
Dalichau, H1
Bakoś, D1
Koller, J1
van der Walt, A1
Barber, JE1
Ratliff, NB1
Ozaki, S2
Yperman, J1
Van Lommel, A1
Verbeken, E2
Trantina, A1
Huma, P1
Rose, AG1
Forman, R1
Bowen, RM1
Zuhdi, N1
Minarini, M1
Ius, P1
Eybl, E2
Müller, MM2
Yellin, EL1
Paule, WJ2
Bernick, S2
Strates, B2
Anselme, K1
Petite, H1
Herbage, D1
Bernacca, GM1
Dimitri, WR1
Fisher, AC1
Mackay, TG1
Wheatley, DJ1
Golomb, G3
Ezra, V2
Griesmacher, A1
Losert, U1
Webb, CL3
Flowers, WE1
Alfrey, AC1
Horton, C1
Imamura, E1
Sawatani, O1
Koyanagi, H1
Miyata, T1
Cheung, D1
Kodama, M1
Sheikh, K1
Sherman, FS1
Nichols, J1
Hawley, MA1
Lund, SA1
Smith, MS1
Linden, J1
Dixon, M1
Ertl, DC1
Nishimoto, SK1
Salka, C1
Strates, BS1
Benedict, JJ1
Linden, JA1
Maranto, AR1

Reviews

9 reviews available for glutaral and Calcinosis

ArticleYear
Bioprostheses and its Alternative Fixation.
    Journal of long-term effects of medical implants, 2017, Volume: 27, Issue:2-4

    Topics: Alkylating Agents; Animals; Bioprosthesis; Bone Density Conservation Agents; Calcinosis; Carbodiimid

2017
The Neglected Villain of Bioprosthetic Degeneration: Inflammatory and Immune Processes.
    Journal of long-term effects of medical implants, 2017, Volume: 27, Issue:2-4

    Topics: Animals; Antibodies; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Foreign-Body Reaction; Giant

2017
[Using chemical methods to crosslink xenogeneic heart valves: the progress of bioprosthetic heart valves].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2003, Volume: 25, Issue:6

    Topics: Animals; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Glutaral; Heart Valve Prosthesis; Heart

2003
Calcification of tissue heart valve substitutes: progress toward understanding and prevention.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:3

    Topics: Animals; Bioprosthesis; Calcinosis; Durapatite; Glutaral; Heart Valve Prosthesis; Humans

2005
Glutaraldehyde and the calcification mechanism of bioprosthetic heart valves.
    The Journal of heart valve disease, 1994, Volume: 3, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Glutaral; Heart Valve Prosthesis; Humans

1994
Acellular vascular tissues: natural biomaterials for tissue repair and tissue engineering.
    Biomaterials, 2000, Volume: 21, Issue:22

    Topics: Animals; Biocompatible Materials; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Cal

2000
Glutaraldehyde fixation revisited.
    Journal of long-term effects of medical implants, 2001, Volume: 11, Issue:3-4

    Topics: Animals; Bioprosthesis; Calcinosis; Collagen; Cross-Linking Reagents; Fixatives; Glutaral; Heart Val

2001
Alternative fixation of bioprostheses.
    Journal of long-term effects of medical implants, 2001, Volume: 11, Issue:3-4

    Topics: Animals; Azides; Bioprosthesis; Calcinosis; Carbodiimides; Cross-Linking Reagents; Epoxy Compounds;

2001
Inflammatory and immune processes: the neglected villain of bioprosthetic degeneration?
    Journal of long-term effects of medical implants, 2001, Volume: 11, Issue:3-4

    Topics: Animals; Antigen Presentation; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Fixatives; Foreign

2001

Trials

1 trial available for glutaral and Calcinosis

ArticleYear
Inhibition of the calcification of porcine valve tissue by selective lipid removal.
    Biomaterials, 1994, Volume: 15, Issue:10

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Chloroform; Female; Glutaral; Heart Valve Prosthes

1994

Other Studies

189 other studies available for glutaral and Calcinosis

ArticleYear
Advantages of decellularized bovine pericardial scaffolds compared to glutaraldehyde fixed bovine pericardial patches demonstrated in a 180-day implant ovine study.
    Cell and tissue banking, 2022, Volume: 23, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Collagen; Glutaral; Pericardium; Sheep

2022
Rapid anticalcification treatment for glutaraldehyde-fixed autologous tissue in cardiovascular surgery.
    Journal of cardiothoracic surgery, 2022, May-31, Volume: 17, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Ethanol; Glutaral; Humans; Male; Rats; Rats, Wistar

2022
Arginine-grafted porcine pericardium by copolymerization to improve the cytocompatibility, hemocompatibility and anti-calcification properties of bioprosthetic heart valve materials.
    Journal of materials chemistry. B, 2022, 07-27, Volume: 10, Issue:29

    Topics: Animals; Arginine; Bioprosthesis; Calcinosis; Glutaral; Heart Valve Prosthesis; Heart Valves; Perica

2022
Well-designed two-fold crosslinked biological valve leaflets with heparin-loaded hydrogel coating for enhancing anticoagulation, endothelialization, and anticalcification.
    Biomaterials science, 2022, Sep-27, Volume: 10, Issue:19

    Topics: Anticoagulants; Calcinosis; Carbodiimides; Glutaral; Heparin; Humans; Hydrogels; Pectins

2022
Inhibition of advanced glycation end product formation and serum protein infiltration in bioprosthetic heart valve leaflets: Investigations of anti-glycation agents and anticalcification interactions with ethanol pretreatment.
    Biomaterials, 2022, Volume: 289

    Topics: Acetylcysteine; Animals; Bioprosthesis; Blood Proteins; Calcinosis; Cattle; Ethanol; Glutaral; Glyca

2022
Sulfonated, oxidized pectin-based double crosslinked bioprosthetic valve leaflets for synergistically enhancing hemocompatibility and cytocompatibility and reducing calcification.
    Journal of materials chemistry. B, 2022, 10-19, Volume: 10, Issue:40

    Topics: Anticoagulants; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Fibrinolytic Agents; Glutaral; He

2022
Dual-crosslinked bioprosthetic heart valves prepared by glutaraldehyde crosslinked pericardium and poly-2-hydroxyethyl methacrylate exhibited improved antithrombogenicity and anticalcification properties.
    Acta biomaterialia, 2022, Volume: 154

    Topics: Animals; Bioprosthesis; Calcinosis; Glutaral; Heart Valve Prosthesis; Heart Valves; Pericardium; Swi

2022
Preventing extrinsic mechanisms of bioprosthetic degeneration using polyphenols.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2023, 04-03, Volume: 63, Issue:4

    Topics: Bioprosthesis; Calcinosis; Glutaral; Heart Valve Prosthesis; Heart Valves; Humans

2023
A versatile modification strategy for functional non-glutaraldehyde cross-linked bioprosthetic heart valves with enhanced anticoagulant, anticalcification and endothelialization properties.
    Acta biomaterialia, 2023, 04-01, Volume: 160

    Topics: Animals; Anticoagulants; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Endothelial Cells; Gluta

2023
A universal strategy for the construction of polymer brush hybrid non-glutaraldehyde heart valves with robust anti-biological contamination performance and improved endothelialization potential.
    Acta biomaterialia, 2023, 04-01, Volume: 160

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Endothelial Cells; Glutaral; Heart Valve Prosthesis; Hea

2023
A versatile drug-controlled release polymer brush hybrid non-glutaraldehyde bioprosthetic heart valves with enhanced anti-inflammatory, anticoagulant and anti-calcification properties, and superior mechanical performance.
    Biomaterials, 2023, Volume: 296

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Bioprosthesis; Calcinosis; Delayed-Action Prepara

2023
Calcification of Various Bioprosthetic Materials in Rats: Is It Really Different?
    International journal of molecular sciences, 2023, Apr-14, Volume: 24, Issue:8

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Collagen; Elastin; Glutaral; Heart Valve Diseas

2023
Postfunctionalization of biological valve leaflets with a polyphenol network and anticoagulant recombinant humanized type III collagen for improved anticoagulation and endothelialization.
    Journal of materials chemistry. B, 2023, 10-06, Volume: 11, Issue:38

    Topics: Animals; Anticoagulants; Calcinosis; Collagen Type III; Glutaral; Heart Valve Prosthesis; Polyphenol

2023
A synergistic strategy of dual-crosslinking and loading intelligent nanogels for enhancing anti-coagulation, pro-endothelialization and anti-calcification properties in bioprosthetic heart valves.
    Acta biomaterialia, 2023, Volume: 171

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Atorvastatin; Bioprosthesis; Calcinosis; Glutaral

2023
A multifunctional bio-patch crosslinked with glutaraldehyde for enhanced mechanical performance, anti-coagulation properties, and anti-calcification properties.
    Journal of materials chemistry. B, 2023, 11-08, Volume: 11, Issue:43

    Topics: Animals; Calcification, Physiologic; Calcinosis; Calcium; Cattle; Glutaral; Porifera; Thrombosis

2023
Inorganic-polymerization crosslinked tissue-siloxane hybrid as potential biomaterial for bioprosthetic heart valves.
    Journal of biomedical materials research. Part A, 2021, Volume: 109, Issue:5

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Blood Coagulation; Calcinosis; Calorimetry, Differe

2021
Elimination of macrophages reduces glutaraldehyde-fixed porcine heart valve degeneration in mice subdermal model.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:1

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Cell Differentiation; Clodronic Acid; Cyt

2021
Oral Use of Phenytoin to Reduce Calcification in Bovine Pericardium and Porcine Aortic Leaflets Implants in Rats.
    Brazilian journal of cardiovascular surgery, 2021, 06-01, Volume: 36, Issue:3

    Topics: Animals; Aorta; Bioprosthesis; Calcinosis; Cattle; Glutaral; Heart Valve Prosthesis; Pericardium; Ph

2021
Anticalcification effect of a combination of decellularization, organic solvents and amino acid detoxification on glutaraldehyde-fixed xenopericardial heart valves in a large-animal long-term circulatory model.
    Interactive cardiovascular and thoracic surgery, 2017, 09-01, Volume: 25, Issue:3

    Topics: Amino Acids; Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Disease Models, Animal; Echocardio

2017
Supercritical carbon dioxide decellularised pericardium: Mechanical and structural characterisation for applications in cardio-thoracic surgery.
    Journal of the mechanical behavior of biomedical materials, 2018, Volume: 77

    Topics: Animals; Biocompatible Materials; Calcinosis; Carbon Dioxide; Cattle; Elastic Modulus; Extracellular

2018
In search of the best xenogeneic material for a paediatric conduit: an analysis of clinical data.
    Interactive cardiovascular and thoracic surgery, 2018, 07-01, Volume: 27, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Child; Child, Preschool; Female; Glutaral; Heart Valve P

2018
A novel tissue treatment to reduce mineralization of bovine pericardial heart valves.
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 156, Issue:1

    Topics: Aldehydes; Animals; Bioprosthesis; Calcinosis; Cattle; Cell Line; Ethanol; Fibroblasts; Fixatives; G

2018
Elastin Stabilization Through Polyphenol and Ferric Chloride Combined Treatment for the Enhancement of Bioprosthetic Heart Valve Anticalcification.
    Artificial organs, 2018, Volume: 42, Issue:11

    Topics: Animals; Bioprosthesis; Calcinosis; Catechin; Chlorides; Collagen; Cross-Linking Reagents; Elastin;

2018
The tropoelastin and lysyl oxidase treatments increased the content of insoluble elastin in bioprosthetic heart valves.
    Journal of biomaterials applications, 2018, Volume: 33, Issue:5

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Catechin; Cross-Linking Reagents; Elast

2018
Calcitonin as an anticalcification treatment for implantable biological tissues.
    Journal of cardiology, 2019, Volume: 73, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Calcitonin; Calcium-Regulating Hormones and Agents; Glutaral; He

2019
The effect of heparin hydrogel embedding on glutaraldehyde fixed bovine pericardial tissues: Mechanical behavior and anticalcification potential.
    Journal of materials science. Materials in medicine, 2018, Nov-09, Volume: 29, Issue:11

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcification, Physiologic; Calcinosis; Calcium; Ca

2018
Riboflavin photo-cross-linking method for improving elastin stability and reducing calcification in bioprosthetic heart valves.
    Xenotransplantation, 2019, Volume: 26, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Glutaral; Heart Valve Prosthesis; Perica

2019
In vivo study of lyophilized bioprostheses: 3 month follow-up in young sheep.
    Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular, 2012, Volume: 27, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Fixatives; Freeze Drying; Glutaral; Heart Valve Prosthes

2012
Cytotoxicity of PVPAC-treated bovine pericardium: a potential replacement for glutaraldehyde in biological heart valves.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2014, Volume: 102, Issue:3

    Topics: 3T3-L1 Cells; Acrolein; Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium Phospha

2014
Combined anticalcification treatment of bovine pericardium with decellularization and hyaluronic acid derivative.
    Bio-medical materials and engineering, 2014, Volume: 24, Issue:1

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Calcium Phosphates; Cattle; Co

2014
Fresh autologous pericardium for leaflet perforation repair in mitral valve infective endocarditis.
    The Journal of heart valve disease, 2013, Volume: 22, Issue:4

    Topics: Adult; Calcinosis; Cardiac Surgical Procedures; Echocardiography; Endocarditis, Bacterial; Female; G

2013
Biostability, durability and calcification of cryopreserved human pericardium after rapid glutaraldehyde-stabilization versus multistep ADAPT(R) treatment in a subcutaneous rat model.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2014, Volume: 45, Issue:4

    Topics: Analysis of Variance; Animals; Calcinosis; Calcium; Cattle; Cryopreservation; Glutaral; Humans; Male

2014
Shrinkage temperature and anti-calcification property of triglycidylamine-crosslinked autologous tissue.
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2014, Volume: 17, Issue:3

    Topics: Animals; Aorta, Thoracic; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Disease Models, Animal;

2014
New engineering treatment of bovine pericardium confers outstanding resistance to calcification in mitral and pulmonary implantations in a juvenile sheep model.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 148, Issue:6

    Topics: Age Factors; Animals; Autografts; Bioengineering; Calcinosis; Calcium; Cardiac Surgical Procedures;

2014
In vivo efficacy for novel combined anticalcification treatment of glutaraldehyde-fixed cardiac xenograft using humanized mice.
    Journal of biomaterials applications, 2015, Volume: 29, Issue:7

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Epitopes; Galactosyltransferases

2015
Development of a next-generation tissue valve using a glutaraldehyde-fixed porcine aortic valve treated with decellularization, α-galactosidase, space filler, organic solvent and detoxification.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2015, Volume: 48, Issue:1

    Topics: alpha-Glucosidases; Animals; Bioprosthesis; Calcinosis; Cardiac Catheterization; Echocardiography; G

2015
Mitral Valve Stenosis Progression Due to Severe Calcification on Glutaraldehyde-Treated Autologous Pericardium: Word of Caution for an Attractive Repair Technique.
    The Annals of thoracic surgery, 2015, Volume: 99, Issue:6

    Topics: Adult; Calcinosis; Cardiac Surgical Procedures; Disease Progression; Echocardiography; Endocarditis,

2015
Photo-oxidized bovine pericardium in congenital cardiac surgery: single-centre experience.
    Interactive cardiovascular and thoracic surgery, 2017, 02-01, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Animals; Calcinosis; Cattle; Child; Child, Preschool; Female; Glutaral; Heart Def

2017
The Immune Responses and Calcification of Bioprostheses in the α1,3-Galactosyltransferase Knockout Mouse.
    The Journal of heart valve disease, 2016, Volume: 25, Issue:2

    Topics: alpha-Galactosidase; Animals; Antibodies; Bioprosthesis; Calcinosis; Cattle; Fixatives; Galactosyltr

2016
Effects of glutaraldehyde concentration and fixation time on material characteristics and calcification of bovine pericardium: implications for the optimal method of fixation of autologous pericardium used for cardiovascular surgery.
    Interactive cardiovascular and thoracic surgery, 2017, 03-01, Volume: 24, Issue:3

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Calcium; Cardiovascular Surgical Proced

2017
Fixation of Bovine Pericardium-Based Tissue Biomaterial with Irreversible Chemistry Improves Biochemical and Biomechanical Properties.
    Journal of cardiovascular translational research, 2017, Volume: 10, Issue:2

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Carbodiimides; Cattle; Cross-Linking Re

2017
Octanediol treatment of glutaraldehyde fixed bovine pericardium: evidence of anticalcification efficacy in the subcutaneous rat model.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2008, Volume: 34, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Disease Models, Animal; Drug Evaluation, Precli

2008
Mitigated calcification of glutaraldehyde-fixed bovine pericardium by tannic acid in rats.
    Chinese medical journal, 2008, Sep-05, Volume: 121, Issue:17

    Topics: Animals; Calcinosis; Cattle; Glutaral; Male; Matrix Metalloproteinase 9; Pericardium; Rats; Rats, Sp

2008
Procyanidins-crosslinked heart valve matrix: anticalcification effect.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2009, Volume: 90, Issue:2

    Topics: Alkaline Phosphatase; Animals; Aorta; Biflavonoids; Biocompatible Materials; Calcinosis; Catechin; C

2009
A novel anti-calcification strategy of bovine pericardium using sodium bisulfite modification.
    The Journal of heart valve disease, 2009, Volume: 18, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Fixatives; Glutaral; Heart Valve Prosthesis; Male; Peric

2009
Development of a new combined test setup for accelerated dynamic pH-controlled in vitro calcification of porcine heart valves.
    The International journal of artificial organs, 2009, Volume: 32, Issue:11

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Equipment Failure Analysis; Fixatives; Gl

2009
Questionable model choice in valve calcification research addressing alpha-Gal.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2010, Volume: 29, Issue:8

    Topics: Animals; Calcinosis; Cardiomyopathies; Disease Models, Animal; Galactosyltransferases; Gene Knockout

2010
High-concentration glutaraldehyde fixation of bovine pericardium in organic solvent and post-fixation glycine treatment: in vitro material assessment and in vivo anticalcification effect.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 39, Issue:3

    Topics: Amino Acids; Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Collagen; Drug Synergism; Female;

2011
Truly stentless autologous pericardial aortic valve replacement: an alternative to standard aortic valve replacement.
    The Journal of thoracic and cardiovascular surgery, 2011, Volume: 141, Issue:1

    Topics: Adult; Aged; Aorta; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Bioprosthesis;

2011
Recellularization of aortic valves in pigs.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 39, Issue:6

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Deoxycholic Acid; Disease Models, Animal; Female;

2011
Cardiac xenotransplantation technology provides materials for improved bioprosthetic heart valves.
    The Journal of thoracic and cardiovascular surgery, 2011, Volume: 141, Issue:1

    Topics: Animals; Animals, Genetically Modified; Antigens, Heterophile; Autoantibodies; Bioprosthesis; Calcin

2011
Mitigation of calcification and cytotoxicity of a glutaraldehyde-preserved bovine pericardial matrix: improved biocompatibility after extended implantation in the subcutaneous rat model.
    The Journal of heart valve disease, 2010, Volume: 19, Issue:6

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Cattle; Cell Survival; Cells,

2010
Combined anti-calcification treatment of bovine pericardium with amino compounds and solvents.
    Interactive cardiovascular and thoracic surgery, 2011, Volume: 12, Issue:6

    Topics: Analysis of Variance; Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Dermis; Ethanol; Female;

2011
Short duration gluteraldehyde cross linking of decellularized bovine pericardium improves biological response.
    Journal of biomedical materials research. Part A, 2011, Jun-01, Volume: 97, Issue:3

    Topics: Animals; Antibody Formation; Bioprosthesis; Calcinosis; Cattle; Cell Line; Cell Survival; Collagenas

2011
Degenerative processes in bioprosthetic mitral valves in juvenile pigs.
    Journal of cardiothoracic surgery, 2011, May-15, Volume: 6

    Topics: Animals; Bioprosthesis; Calcinosis; Disease Models, Animal; Echocardiography; Female; Glutaral; Graf

2011
In vitro properties and performance of glutaraldehyde-crosslinked bovine pericardial bioprostheses treated with glutamic acid.
    Artificial organs, 2011, Volume: 35, Issue:5

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Equipme

2011
Anticalcification effects of decellularization, solvent, and detoxification treatment for genipin and glutaraldehyde fixation of bovine pericardium.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 41, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Enzyme-Linked Immunosorbent Assay; Fixatives; G

2012
Effects of glutaraldehyde concentration, pretreatment time, and type of tissue (porcine versus bovine) on postimplantation calcification.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:1

    Topics: Animals; Calcinosis; Cattle; Dose-Response Relationship, Drug; Fixatives; Glutaral; Postoperative Co

2012
Neomycin and carbodiimide crosslinking as an alternative to glutaraldehyde for enhanced durability of bioprosthetic heart valves.
    Journal of biomaterials applications, 2013, Volume: 27, Issue:8

    Topics: Animals; Aortic Valve; Biocompatible Materials; Biomechanical Phenomena; Bioprosthesis; Calcinosis;

2013
Immune response to bovine pericardium implanted into α1,3-galactosyltransferase knockout mice: feasibility as an animal model for testing efficacy of anticalcification treatments of xenografts.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 42, Issue:1

    Topics: Animals; Biomarkers; Calcinosis; Cattle; Feasibility Studies; Fixatives; Galactosyltransferases; Glu

2012
Will the real culprit of heterograft valve calcification please stand up?
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:1

    Topics: Animals; Calcinosis; Fixatives; Glutaral; Postoperative Complications; Transplantation

2012
Detoxification on top of enhanced, diamine-extended glutaraldehyde fixation significantly reduces bioprosthetic root calcification in the sheep model.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Diamines; Glutaral; Heart Valve Prosthes

2003
Calcification resistance with aluminum-ethanol treated porcine aortic valve bioprostheses in juvenile sheep.
    The Annals of thoracic surgery, 2003, Volume: 75, Issue:4

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Aortic Valve; Bioprosthesis; Calcinosis; Chlorides;

2003
Glycosaminoglycan-degrading enzymes in porcine aortic heart valves: implications for bioprosthetic heart valve degeneration.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:2

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Chondroitinases and Chondroitin Lyases; D

2003
Porcine stentless bioprostheses: prevention of aortic wall calcification by dye-mediated photo-oxidation.
    Artificial organs, 2003, Volume: 27, Issue:6

    Topics: Animals; Aorta; Aortic Diseases; Bioprosthesis; Calcinosis; Coloring Agents; Fixatives; Glutaral; He

2003
Glutaraldehyde-fixed kangaroo aortic wall tissue: histology, crosslink stability and calcification potential.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2003, Jul-15, Volume: 66, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Collagen; Cross-Linking Reagents; Elastin; Fixatives; G

2003
Role of elastin in pathologic calcification of xenograft heart valves.
    Journal of biomedical materials research. Part A, 2003, Jul-01, Volume: 66, Issue:1

    Topics: Amino Acids; Animals; Aorta; Aortic Diseases; Bioprosthesis; Calcinosis; Cross-Linking Reagents; Cya

2003
Malachite green and phthalocyanine-silver reactions reveal acidic phospholipid involvement in calcification of porcine aortic valves in rat subdermal model.
    Histology and histopathology, 2003, Volume: 18, Issue:4

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Coloring Agents; Fixatives; Glutaral; Heart Valve

2003
Treatment of bioprosthetic heart valve tissue with long chain alcohol solution to lower calcification potential.
    Journal of biomedical materials research. Part A, 2004, Apr-01, Volume: 69, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Ethanol; Glutaral; Glycols; Hear

2004
Ethanol inhibition of porcine bioprosthetic heart valve cusp calcification is enhanced by reduction with sodium borohydride.
    The Journal of heart valve disease, 2004, Volume: 13, Issue:3

    Topics: Animals; Aortic Valve; Bioprosthesis; Borohydrides; Calcinosis; Cross-Linking Reagents; Ethanol; Glu

2004
Hyaluronic acid grafting mitigates calcification of glutaraldehyde-fixed bovine pericardium.
    Journal of biomedical materials research. Part A, 2004, Aug-01, Volume: 70, Issue:2

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Female; Fixatives; Glutaral; He

2004
ADAPT-treated porcine valve tissue (cusp and wall) versus Medtronic Freestyle and Prima Plus: crosslink stability and calcification behavior in the subcutaneous rat model.
    The Journal of heart valve disease, 2004, Volume: 13, Issue:4

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Cellulose; Cross-Linking Reagents; Diseas

2004
Tannic acid treatment enhances biostability and reduces calcification of glutaraldehyde fixed aortic wall.
    Biomaterials, 2005, Volume: 26, Issue:11

    Topics: Animals; Aorta; Bioprosthesis; Calcinosis; Cattle; Drug Combinations; Elasticity; Elastin; Glutaral;

2005
Carbodiimide treatment dramatically potentiates the anticalcific effect of alpha-amino oleic acid on glutaraldehyde-fixed aortic wall tissue.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:3

    Topics: Animals; Aorta, Thoracic; Aortic Diseases; Bioprosthesis; Calcinosis; Drug Synergism; Ethyldimethyla

2005
Comparative study of the L-hydro process and glutaraldehyde preservation.
    Asian cardiovascular & thoracic annals, 2005, Volume: 13, Issue:3

    Topics: Animals; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Bioprosthesis; Calci

2005
Diamine-extended glutaraldehyde- and carbodiimide crosslinks act synergistically in mitigating bioprosthetic aortic wall calcification.
    The Journal of heart valve disease, 2005, Volume: 14, Issue:4

    Topics: Animals; Aorta; Aortic Diseases; Biocompatible Materials; Bioprosthesis; Calcinosis; Carbodiimides;

2005
Reduction of calcification of carbodiimide-processed heart valve tissue by prior blocking of amine groups with monoaldehydes.
    The Journal of heart valve disease, 2006, Volume: 15, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Carbodiimides; Cross-Linking Reagents; Disease Models, Animal; G

2006
Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection.
    Circulation, 2006, Jul-25, Volume: 114, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Cell Movement; Glutaral; Graft Rejection; Guinea Pigs; Heart Val

2006
A multi-step approach in anti-calcification of glutaraldehyde-preserved bovine pericardium.
    The Journal of cardiovascular surgery, 2006, Volume: 47, Issue:6

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Collagen; Cross-Linking Reagents; Fixatives; Gl

2006
Stentless valves treated by the L-hydro process in the aortic position in sheep.
    Asian cardiovascular & thoracic annals, 2007, Volume: 15, Issue:5

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Equipment Failure Analysis; Female; Fixatives; Glu

2007
Histological evaluation of biocompatibility of lyophilized bovine pericardium implanted subcutaneously in rats.
    Artificial organs, 2008, Volume: 32, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Cicatrix; Cross-Linking Reagents; Freeze Drying; Glutara

2008
Early stenosis and calcification of glutaraldehyde-preserved porcine xenografts in children.
    The Thoracic and cardiovascular surgeon, 1981, Volume: 29, Issue:6

    Topics: Adolescent; Aldehydes; Animals; Aortic Valve; Bioprosthesis; Calcinosis; Child; Child, Preschool; Fe

1981
Intrinsic calcification of T6-processed and control porcine and bovine bioprostheses in calves.
    Transactions - American Society for Artificial Internal Organs, 1983, Volume: 29

    Topics: Animals; Aorta; Calcinosis; Calcium; Cattle; Glutaral; Heart Valve Prosthesis; Swine; Time Factors

1983
Severe calcification of glutaraldehyde-preserved porcine xenografts in children.
    The American journal of cardiology, 1980, Volume: 45, Issue:3

    Topics: Adolescent; Bioprosthesis; Calcinosis; Female; Glutaral; Heart Valve Prosthesis; Humans; Male; Mitra

1980
Possible causes for the calcification of glutaraldehyde-treated tissue heart valves and blood contacting elastomers during prolonged use in medical devices: a physico-chemical view.
    Biomaterials, 1981, Volume: 2, Issue:1

    Topics: Aldehydes; Animals; Bioprosthesis; Blood; Calcinosis; Glutaral; Heart Valve Prosthesis; Heart Valves

1981
Longevity of the formaldehyde-preserved Hancock porcine heterograft.
    The Journal of thoracic and cardiovascular surgery, 1982, Volume: 84, Issue:3

    Topics: Adult; Aortic Valve; Bioprosthesis; Calcinosis; Female; Formaldehyde; Glutaral; Heart Valve Prosthes

1982
Structural changes of glutaraldehyde- treated porcine bioprosthetic valves.
    Archives of pathology & laboratory medicine, 1982, Volume: 106, Issue:10

    Topics: Adolescent; Adult; Aged; Aldehydes; Aortic Valve; Bioprosthesis; Calcinosis; Child; Collagen; Connec

1982
Comparison of fresh and glutaraldehyde-treated autologous stented pericardium as pulmonary valve replacement.
    Journal of cardiac surgery, 1995, Volume: 10, Issue:5

    Topics: Animals; Bioprosthesis; Calcinosis; Collagen; Echocardiography; Endothelium, Vascular; Glutaral; Hea

1995
In situ mitral valve stabilization with glutaraldehyde.
    The Journal of heart valve disease, 1995, Volume: 4, Issue:4

    Topics: Animals; Calcinosis; Calcium; Chordae Tendineae; Disease Models, Animal; Echocardiography, Doppler;

1995
A comparison of failure modes of glutaraldehyde-treated versus antibiotic-preserved mitral valve allografts implanted in sheep.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bioprosthesis; Calcinosis; Calcium; Chordae Tendineae; Collagen; End

1995
Prevention of calcification of heart valve bioprostheses: an experimental study in rat.
    The Annals of thoracic surgery, 1995, Volume: 60, Issue:2 Suppl

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Chitin; Chitosan; Glutaral; Heart Valve Prosthesis; Hea

1995
Time-dependent effect of glutaraldehyde on the tendency to calcify of both autografts and xenografts.
    The Annals of thoracic surgery, 1995, Volume: 60, Issue:2 Suppl

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Glutaral; Heart Valve Prosthesis; Heart Valves; Male; R

1995
Bioprosthetic cardiac valve degeneration: role of inflammatory and immune reactions.
    The Journal of heart valve disease, 1993, Volume: 2, Issue:6

    Topics: Animals; Antibody Formation; Biodegradation, Environmental; Bioprosthesis; Calcinosis; Cattle; Colla

1993
Prevention of calcification of tissue valves.
    Artificial organs, 1994, Volume: 18, Issue:10

    Topics: Animals; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Cattle; Chitin; Chitosan; Collagenases;

1994
Effect of 2-amino oleic acid exposure conditions on the inhibition of calcification of glutaraldehyde cross-linked porcine aortic valves.
    Journal of biomedical materials research, 1994, Volume: 28, Issue:12

    Topics: Animals; Aortic Valve; Bioprosthesis; Borohydrides; Calcinosis; Calcium; Diffusion; Glutaral; Heart

1994
Mechanism of efficacy of 2-amino oleic acid for inhibition of calcification of glutaraldehyde-pretreated porcine bioprosthetic heart valves.
    Circulation, 1994, Volume: 90, Issue:1

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Diffusion; Glutaral; In Vitro Techniques;

1994
Anticalcification treatment of pericardial prostheses.
    Biomaterials, 1994, Volume: 15, Issue:6

    Topics: Animals; Antigens; Calcinosis; Cattle; Chitin; Chitosan; Collagenases; Glutaral; Heart Valve Prosthe

1994
Biomechanical and structural properties of the explanted bioprosthetic valve leaflets.
    Journal of biomechanics, 1994, Volume: 27, Issue:1

    Topics: Adult; Animals; Aortic Valve; Biomechanical Phenomena; Bioprosthesis; Calcinosis; Cattle; Child; Col

1994
Inhibition of calcification of glutaraldehyde pretreated porcine aortic valve cusps with sodium dodecyl sulfate: preincubation and controlled release studies.
    Journal of biomedical materials research, 1993, Volume: 27, Issue:12

    Topics: Animals; Aortic Valve; Biocompatible Materials; Calcinosis; Cattle; Delayed-Action Preparations; Dif

1993
Trivalent metal ions in the prevention of calcification in glutaraldehyde treated biological tissues. Is there a chemical correlation?
    Biomaterials, 1993, Volume: 14, Issue:13

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Chlorides; Ferric Compounds; Gadolinium; Glutaral; Hear

1993
Spontaneous host endothelial growth on bioprosthetic valves and its relation to calcification.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1993, Volume: 7, Issue:11

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Disease Models, Animal; Endothe

1993
Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat subdermal model by FeCl3 and ethanehydroxydiphosphonate: preincubation and polymeric controlled release studies.
    Biomaterials, 1993, Volume: 14, Issue:9

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Chlorides; Delayed-Action Preparations; Disease Models,

1993
Effects of fixation back pressure and antimineralization treatment on the morphology of porcine aortic bioprosthetic valves.
    The Journal of thoracic and cardiovascular surgery, 1993, Volume: 105, Issue:1

    Topics: Aortic Valve; Bioprosthesis; Biopsy; Calcinosis; Collagen; Elastin; Evaluation Studies as Topic; Glu

1993
Effects of glutaraldehyde on experimental arterial iso- and allografts in rats.
    The Journal of surgical research, 1993, Volume: 54, Issue:1

    Topics: Animals; Aorta; Calcinosis; Elastin; Glutaral; Graft Rejection; Rats; Rats, Inbred BN; Rats, Inbred

1993
Effects of metallic ions and diphosphonates on inhibition of pericardial bioprosthetic tissue calcification and associated alkaline phosphatase activity.
    Biomaterials, 1993, Volume: 14, Issue:5

    Topics: Alkaline Phosphatase; Animals; Bioprosthesis; Calcinosis; Cattle; Diphosphonates; Etidronic Acid; Gl

1993
A comparison between glutaraldehyde and diepoxide-fixed stentless porcine aortic valves: biochemical and mechanical characterization and resistance to mineralization.
    The Journal of heart valve disease, 1995, Volume: 4 Suppl 1

    Topics: Animals; Aortic Valve; Biochemical Phenomena; Biochemistry; Biomechanical Phenomena; Bioprosthesis;

1995
Calcification of pericardial tissue pretreated with different amino acids.
    Biomaterials, 1996, Volume: 17, Issue:6

    Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Bioprosthesis; Calcinosis; Calcium; Cardiomyop

1996
Structural studies on bovine bioprosthetic tissues and their in vivo calcification: prevention via drug delivery.
    Biomaterials, 1996, Volume: 17, Issue:6

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium Phosphates; Cattle; Chitin; Chi

1996
Calcification of bovine pericardium: glutaraldehyde versus No-React biomodification.
    The Annals of thoracic surgery, 1996, Volume: 62, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Foreign-Body Reaction; Glutaral; Heart Valve Prosthesis;

1996
Use of the glutaraldehyde-chitosan-treated porcine pericardium as a pericardial substitute.
    Biomaterials, 1996, Volume: 17, Issue:11

    Topics: Animals; Calcinosis; Cardiac Surgical Procedures; Cardiomyopathies; Chitin; Chitosan; Dogs; Glutaral

1996
Impact of glutaraldehyde on calcification of pericardial bioprosthetic heart valve material.
    The Annals of thoracic surgery, 1996, Volume: 62, Issue:3

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Cell Division; Cells, Cultured; Endothe

1996
Feasibility evaluation of a new pericardial bioprosthesis with dye mediated photo-oxidized bovine pericardial tissue.
    The Journal of heart valve disease, 1996, Volume: 5, Issue:3

    Topics: Angiography; Animals; Bioprosthesis; Calcinosis; Cattle; Coloring Agents; Evaluation Studies as Topi

1996
Combined use of malachite green fixation and PLA2-gold complex technique to localize phospholipids in areas of early calcification of rat epiphyseal cartilage and bone.
    Bone, 1996, Volume: 18, Issue:6

    Topics: Animals; Calcinosis; Coloring Agents; Endoplasmic Reticulum, Rough; Epoxy Resins; Glutaral; Growth P

1996
Efficacy of the chitosan posttreatment in calcification prevention of the glutaraldehyde-treated porcine aortic noncoronary cusp implanted in the right ventricular outflow tract in dogs.
    Artificial organs, 1996, Volume: 20, Issue:7

    Topics: Animals; Aorta; Biocompatible Materials; Calcinosis; Chitin; Chitosan; Dogs; Glutaral; Heart Valve P

1996
Calcification of cross-linked collagen-elastin membrane implants in vivo and their proposed use in bone regeneration.
    Biomaterials, 1996, Volume: 17, Issue:15

    Topics: Animals; Biocompatible Materials; Bone and Bones; Calcinosis; Collagen; Elastin; Glutaral; Inflammat

1996
Amide cross-linking: an alternative to glutaraldehyde fixation.
    The Journal of heart valve disease, 1996, Volume: 5, Issue:5

    Topics: Amides; Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Caprylates; Cross-Linking Reagent

1996
No-react detoxification process: a superior anticalcification method for bioprostheses.
    The Annals of thoracic surgery, 1996, Volume: 62, Issue:6

    Topics: Animals; Aortic Valve; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Cell Survival; C

1996
Prevention of bioprosthetic heart valve calcification by ethanol preincubation. Efficacy and mechanisms.
    Circulation, 1997, Jan-21, Volume: 95, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Collagen; Cross-Linking Reagents; Dermatologic Surgical

1997
Is the dog a useful model for accelerated calcification study of cardiovascular bioprostheses?
    Artificial organs, 1997, Volume: 21, Issue:5

    Topics: Animals; Aorta, Thoracic; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Chelating Agen

1997
Effect of alternative crosslinking techniques on the enzymatic degradation of bovine pericardia and their calcification.
    Journal of biomedical materials research, 1997, Jun-05, Volume: 35, Issue:3

    Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Blood Platelets; Calcinosis; Carbod

1997
Influence of polyethylene glycol graftings on the in vitro degradation and calcification of bovine pericardium.
    Journal of biomaterials applications, 1997, Volume: 11, Issue:4

    Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Bioprosthesis; Calcinosis; Calcium

1997
Factors which affect the calcification of tissue-derived bioprostheses.
    Journal of biomedical materials research, 1997, Jun-15, Volume: 35, Issue:4

    Topics: Animals; Calcification, Physiologic; Calcinosis; Glutaral; Prostheses and Implants; Rats; Rats, Inbr

1997
Heparin in calcification prevention of porcine pericardial bioprostheses.
    Biomaterials, 1997, Volume: 18, Issue:16

    Topics: Animals; Anticoagulants; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Cross-Linking

1997
New-generation valved conduit: an experimental study.
    The Journal of thoracic and cardiovascular surgery, 1997, Volume: 114, Issue:2

    Topics: Animals; Aorta, Thoracic; Aortic Valve; Bioprosthesis; Blood Vessel Prosthesis; Calcinosis; Cross-Li

1997
Glutaraldehyde treated bovine pericardium: changes in calcification due to vitamins and platelet inhibitors.
    Artificial organs, 1997, Volume: 21, Issue:9

    Topics: Animals; Ascorbic Acid; Aspirin; Biological Transport; Bioprosthesis; Calcinosis; Calcium; Calcium P

1997
Calcification potential of small intestinal submucosa in a rat subcutaneous model.
    The Journal of surgical research, 1997, Volume: 71, Issue:2

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Glutaral; Intestinal Mucosa; Intestine,

1997
Valved conduit in the descending thoracic aorta in juvenile sheep: a useful, cost-effective model for accelerated calcification study in systemic circulation.
    Biomaterials, 1997, Volume: 18, Issue:19

    Topics: Animals; Aorta, Thoracic; Aortic Valve; Calcinosis; Calcium; Cost-Benefit Analysis; Glutaral; Heart

1997
Tanning revisited for leaflets and the aortic wall.
    The Journal of heart valve disease, 1997, Volume: 6, Issue:5

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Fixatives; Glutaral; Heart Valve Prosthesis; Human

1997
High glutaraldehyde concentrations reduce rather than increase the calcification of aortic wall tissue.
    The Journal of heart valve disease, 1997, Volume: 6, Issue:5

    Topics: Abdominal Muscles; Animals; Aorta, Thoracic; Bioprosthesis; Calcinosis; Cold Temperature; Fixatives;

1997
Glutaraldehyde detoxification of aortic wall tissue: a promising perspective for emerging bioprosthetic valve concepts.
    The Journal of heart valve disease, 1997, Volume: 6, Issue:5

    Topics: Acetic Acid; Amines; Amino Acids; Amino Sugars; Animals; Aorta; Aortic Valve; Bioprosthesis; Calcino

1997
Prevention of calcification in glutaraldehyde-treated porcine aortic and pulmonary valves.
    The Annals of thoracic surgery, 1997, Volume: 64, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Glutaral; Heart Valve Prosthesis; Heparin; Male; Prosthesis Fail

1997
Changes in serum conditioning profiles of glutaraldehyde-crosslinked collagen sponges after their treatment with calcification inhibitors.
    Journal of biomedical materials research, 1998, Jun-05, Volume: 40, Issue:3

    Topics: Blood Physiological Phenomena; Calcinosis; Chlorides; Collagen; Cross-Linking Reagents; Culture Medi

1998
Pathologic findings in explanted clinical bioprosthetic valves fabricated from photooxidized bovine pericardium.
    The Journal of heart valve disease, 1998, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Animals; Aortic Valve; Aortic Valve Insufficiency; Bioprosthesis; Calcinosi

1998
Acidic glycoproteins accumulate in calcified areas of bioprosthetic tissue.
    The Journal of heart valve disease, 1998, Volume: 7, Issue:2

    Topics: Analysis of Variance; Animals; Bioprosthesis; Calcinosis; Calcium; Cardiomyopathies; Cattle; Collage

1998
Prevention of calcification of glutaraldehyde-crosslinked porcine aortic cusps by ethanol preincubation: mechanistic studies of protein structure and water-biomaterial relationships.
    Journal of biomedical materials research, 1998, Jun-15, Volume: 40, Issue:4

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Cholesterol; Collagen; Collage

1998
Detoxified glutaraldehyde cross-linked pericardium: tissue preservation and mineralization mitigation in a subcutaneous rat model.
    The Journal of heart valve disease, 1998, Volume: 7, Issue:3

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Electron Probe Microanalysis; G

1998
Changes in pericardial calcification due to antiplatelet agents: in vitro studies.
    Artificial organs, 1998, Volume: 22, Issue:8

    Topics: Anesthetics, Intravenous; Animals; Anti-Bacterial Agents; Aspirin; Bioprosthesis; Calcinosis; Cattle

1998
Polyethylene glycol (PEG) modified bovine pericardium as a biomaterial: a comparative study on immunogenicity.
    Journal of biomaterials applications, 1998, Volume: 13, Issue:2

    Topics: Animals; Bioprosthesis; Blood Proteins; Calcinosis; Calcium; Cattle; Coated Materials, Biocompatible

1998
Evaluation of porcine valves prepared by dye-mediated photooxidation.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:6 Suppl

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Coloring Agents; Evaluation Studies as Topic; F

1998
Comparison of different anticalcification treatments for stentless bioprostheses.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:6 Suppl

    Topics: Aluminum; Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Disease Models, Animal; Durapat

1998
Does glutaraldehyde induce calcification of bioprosthetic tissues?
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:6 Suppl

    Topics: Analysis of Variance; Animals; Bioprosthesis; Calcinosis; Calcium; Female; Fixatives; Follow-Up Stud

1998
Heat treatment mitigates calcification of valvular bioprostheses.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:6 Suppl

    Topics: Animals; Animals, Newborn; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Cattle; Female; Fixativ

1998
Role of glutaraldehyde in calcification of porcine aortic valve fibroblasts.
    The American journal of pathology, 1999, Volume: 154, Issue:3

    Topics: Animals; Aortic Valve; Calcinosis; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Dr

1999
Characterization of a polyepoxy compound fixed porcine heart valve bioprosthesis.
    Journal of applied biomaterials : an official journal of the Society for Biomaterials, 1994,Summer, Volume: 5, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Epoxy Compounds; Formaldehyde; Glutaral; Heart Valve Prosthesis;

1994
Effectiveness of different anticalcification treatments for stentless aortic bioprostheses.
    The Thoracic and cardiovascular surgeon, 1999, Volume: 47, Issue:1

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Aorta, Thoracic; Aortic Diseases; Aortic Valve; Astr

1999
No-React anticalcification tissue treatment results with stentless heart valves in two adolescents.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 117, Issue:6

    Topics: Adolescent; Bioprosthesis; Calcinosis; Female; Glutaral; Heart Valve Prosthesis; Heparin; Humans; Ma

1999
Mineralization of glutaraldehyde-fixed porcine aortic valve cusps in the subcutaneous rat model: analysis of variations in implant site and cuspal quadrants.
    Journal of biomedical materials research, 1999, Jun-05, Volume: 45, Issue:3

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Glutaral; Heart Valve Prosthesis; Injecti

1999
Elastin calcification and its prevention with aluminum chloride pretreatment.
    The American journal of pathology, 1999, Volume: 155, Issue:3

    Topics: Aluminum Chloride; Aluminum Compounds; Amino Acids; Animals; Calcinosis; Cattle; Chlorides; Circular

1999
Heparin coupling in inhibition of calcification of vascular bioprostheses.
    Biomaterials, 1999, Volume: 20, Issue:19

    Topics: Animals; Aorta; Aorta, Thoracic; Biocompatible Materials; Blood Vessel Prosthesis; Calcinosis; Calci

1999
In vivo behavior of epoxy-crosslinked porcine heart valve cusps and walls.
    Journal of biomedical materials research, 2000, Volume: 53, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Carbodiimides; Coated Materials, Biocompatible; Cross-Linking Re

2000
Effects of double cross-linking technique on the enzymatic degradation and calcification of bovine pericardia.
    Journal of biomaterials applications, 2000, Volume: 14, Issue:3

    Topics: Animals; Biodegradation, Environmental; Calcinosis; Cattle; Collagenases; Cross-Linking Reagents; Gl

2000
The anticalcification effect of polyethylene glycol-immobilized on hexamethylene diisocyanate treated pericardium.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2000, Volume: 28, Issue:1

    Topics: Animals; Calcinosis; Calcium; Cattle; Cross-Linking Reagents; Cyanates; Endopeptidases; Glutaral; Is

2000
Glutaraldehyde detoxification in addition to enhanced amine cross-linking dramatically reduces bioprosthetic tissue calcification in the rat model.
    The Journal of heart valve disease, 2000, Volume: 9, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Equipment Failure Analysis; Fixa

2000
Covalently bonded heparin to alter the pericardial calcification.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2000, Volume: 28, Issue:3

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Cross-Linking Reagents; Diffusion; Glutaral; He

2000
Calcification of leaflets from porcine aortic valves crosslinked by ultraviolet irradiation.
    Artificial organs, 2000, Volume: 24, Issue:7

    Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Cross-Linking Reagents; Glutaral; Heart V

2000
Improved calcification resistance and biocompatibility of tissue patch grafted with sulfonated PEO or heparin after glutaraldehyde fixation.
    Journal of biomedical materials research, 2001, Volume: 58, Issue:1

    Topics: Animals; Aorta, Thoracic; Biocompatible Materials; Bioprosthesis; Borohydrides; Calcinosis; Cattle;

2001
High glutaraldehyde concentrations mitigate bioprosthetic root calcification in the sheep model.
    The Annals of thoracic surgery, 2000, Volume: 70, Issue:6

    Topics: Animals; Aorta, Thoracic; Bioprosthesis; Blood Vessel Prosthesis Implantation; Calcinosis; Dose-Resp

2000
Influence of glutaraldehyde fixation on the detection of SLA-I and II antigens and calcification tendency in porcine cardiac tissue.
    Scandinavian cardiovascular journal : SCJ, 2000, Volume: 34, Issue:6

    Topics: Animals; Bioprosthesis; Calcinosis; Cardiomyopathies; Female; Glutaral; Heart Valve Prosthesis; Hist

2000
Tissue reactions to epoxy-crosslinked porcine heart valves post-treated with detergents or a dicarboxylic acid.
    Journal of biomedical materials research, 2001, Jun-05, Volume: 55, Issue:3

    Topics: Animals; Bioprosthesis; Butylene Glycols; Calcinosis; Carbodiimides; Cross-Linking Reagents; Deterge

2001
Resorption and calcification of chemically modified collagen/hyaluronan hybrid membranes.
    Polimery w medycynie, 2000, Volume: 30, Issue:3-4

    Topics: Administration, Cutaneous; Animals; Azides; Biocompatible Materials; Biodegradation, Environmental;

2000
Calcification resistance, biostability, and low immunogenic potential of porcine heart valves modified by dye-mediated photooxidation.
    Journal of biomedical materials research, 2001, Volume: 56, Issue:1

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Collagen; Coloring Agents; Fix

2001
Diamine extension of glutaraldehyde crosslinks mitigates bioprosthetic aortic wall calcification in the sheep model.
    Journal of biomedical materials research, 2001, Volume: 56, Issue:1

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Cross-Linking Reagents; Diamines; Fixatives; Follow-Up

2001
Cellular mechanism of calcification and its prevention in glutaraldehyde treated vascular tissue.
    Zeitschrift fur Kardiologie, 2001, Volume: 90 Suppl 3

    Topics: Animals; Aorta; Bioprosthesis; Calcinosis; Calcium Channel Blockers; Cell Division; Cells, Cultured;

2001
Tissue damage and calcification may be independent mechanisms of bioprosthetic heart valve failure.
    The Journal of heart valve disease, 2001, Volume: 10, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Equipment Failure Analysis; Female; Fixatives; Glutaral; Graft S

2001
Antimineralization treatments in stentless porcine bioprostheses: an experimental study.
    The Journal of heart valve disease, 2001, Volume: 10, Issue:4

    Topics: Animals; Bioprosthesis; Calcinosis; Calcium; Fixatives; Glutaral; Microscopy, Electron; Models, Anim

2001
Fixation-related autolysis and bioprosthetic aortic wall calcification.
    The Journal of heart valve disease, 2001, Volume: 10, Issue:5

    Topics: Animals; Aorta; Aortic Valve; Autolysis; Bioprosthesis; Calcinosis; Calcium; Cardiovascular Surgical

2001
Influence of steroid hormones on bovine pericardial calcification.
    Journal of biomaterials applications, 2001, Volume: 16, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Glutaral; Gonadal Steroid Hormones; Heart Valve Prosthes

2001
Influence of species, environmental factors, and tissue cellularity on calcification of porcine aortic wall tissue.
    Seminars in thoracic and cardiovascular surgery, 2001, Volume: 13, Issue:4 Suppl 1

    Topics: Animals; Aorta; Bioprosthesis; Calcinosis; Carotid Arteries; Cross-Linking Reagents; Disease Models,

2001
Optimization of diamine bridges in glutaraldehyde treated bioprosthetic aortic wall tissue.
    Biomaterials, 2002, Volume: 23, Issue:10

    Topics: Animals; Aorta, Thoracic; Bioprosthesis; Calcinosis; Calcium; Diamines; Dose-Response Relationship,

2002
Calcification of glutaraldehyde-fixed porcine xenograft.
    Thorax, 1978, Volume: 33, Issue:1

    Topics: Adolescent; Aldehydes; Animals; Calcinosis; Connective Tissue; Glutaral; Heart Valve Diseases; Heart

1978
The porcine aortic valve bioprosthesis: a significant alternative.
    The Annals of thoracic surgery, 1976, Volume: 21, Issue:6

    Topics: Animals; Aortic Valve; Aortic Valve Insufficiency; Calcinosis; Follow-Up Studies; Glutaral; Heart Va

1976
Durability of glutaraldehyde-fixed pericardial valve prostheses: clinical and animal experimental studies.
    The Journal of heart valve disease, 1992, Volume: 1, Issue:2

    Topics: Adult; Aged; Animals; Bioprosthesis; Calcinosis; Cattle; Fixatives; Glutaral; Heart Valve Diseases;

1992
Improved biocompatibility of bioprosthetic heart valves by L-glutamic acid treatment.
    Journal of cardiac surgery, 1992, Volume: 7, Issue:1

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Endothelium; Glutamates; Glutam

1992
Diphenylhydantoin inhibits calcification of bovine pericardial implants and myocardium: a preliminary study.
    The Journal of surgical research, 1992, Volume: 53, Issue:4

    Topics: Animals; Bioprosthesis; Body Weight; Calcification, Physiologic; Calcinosis; Cardiomyopathies; Cattl

1992
Calcification of implanted vascular tissues associated with elastin in an experimental animal model.
    Journal of biomedical materials research, 1992, Volume: 26, Issue:9

    Topics: Animals; Calcinosis; Calcium; Cross-Linking Reagents; Disease Models, Animal; Elastin; Glutaral; Mal

1992
Inhibition of calcification in vivo by acyl azide cross-linking of a collagen-glycosaminoglycan sponge.
    Matrix (Stuttgart, Germany), 1992, Volume: 12, Issue:4

    Topics: Animals; Biocompatible Materials; Calcinosis; Collagen; Cross-Linking Reagents; Foreign-Body Reactio

1992
Chemical modification of bovine pericardium and its effect on calcification in the rat subdermal model.
    Biomaterials, 1992, Volume: 13, Issue:6

    Topics: Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Cattle; Collagen; Cross-Linking Reagent

1992
Covalent binding of protamine by glutaraldehyde to bioprosthetic tissue: characterization and anticalcification effect.
    Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1992, Volume: 20, Issue:1

    Topics: Amino Acids; Animals; Calcinosis; Cross-Linking Reagents; Glutaral; Heart Valve Prosthesis; Pericard

1992
Biocompatibility of aldehyde-fixed bovine pericardium. An in vitro and in vivo approach toward improvement of bioprosthetic heart valves.
    The Journal of thoracic and cardiovascular surgery, 1991, Volume: 102, Issue:2

    Topics: Animals; Bioprosthesis; Calcinosis; Cattle; Cell Division; Endothelium; Glutamates; Glutamic Acid; G

1991
Inhibition of mineralization of glutaraldehyde-pretreated bovine pericardium by AlCl3. Mechanisms and comparisons with FeCl3, LaCl3, and Ga(NO3)3 in rat subdermal model studies.
    The American journal of pathology, 1991, Volume: 138, Issue:4

    Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Calcinosis; Cardiomyopathies; Cattle; Chlo

1991
Prevention of bioprosthetic heart valve tissue calcification by charge modification: effects of protamine binding by formaldehyde.
    Journal of biomedical materials research, 1991, Volume: 25, Issue:1

    Topics: Biocompatible Materials; Bioprosthesis; Calcinosis; Electrochemistry; Formaldehyde; Glutaral; Heart

1991
Covalent binding of aminopropanehydroxydiphosphonate to glutaraldehyde residues in pericardial bioprosthetic tissue: stability and calcification inhibition studies.
    Experimental and molecular pathology, 1989, Volume: 50, Issue:3

    Topics: Aldehydes; Animals; Bioprosthesis; Calcinosis; Diphosphonates; Disease Models, Animal; Glutaral; Hea

1989
Epoxy compounds as a new cross-linking agent for porcine aortic leaflets: subcutaneous implant studies in rats.
    Journal of cardiac surgery, 1989, Volume: 4, Issue:1

    Topics: Animals; Aortic Valve; Biocompatible Materials; Bioprosthesis; Calcinosis; Cross-Linking Reagents; E

1989
Chemically modified collagen: a natural biomaterial for tissue replacement.
    Journal of biomedical materials research, 1987, Volume: 21, Issue:6

    Topics: Adenosine Diphosphate; Animals; Biocompatible Materials; Bioprosthesis; Calcinosis; Calcium; Chondro

1987
Calcification of subcutaneously implanted type I collagen sponges. Effects of formaldehyde and glutaraldehyde pretreatments.
    The American journal of pathology, 1986, Volume: 122, Issue:1

    Topics: Aldehydes; Animals; Calcinosis; Collagen; Cross-Linking Reagents; Foreign-Body Reaction; Formaldehyd

1986
The role of glutaraldehyde-induced cross-links in calcification of bovine pericardium used in cardiac valve bioprostheses.
    The American journal of pathology, 1987, Volume: 127, Issue:1

    Topics: Aldehydes; Animals; Bioprosthesis; Calcinosis; Cattle; Cross-Linking Reagents; Diffusion; Glutaral;

1987
Biochemical differences between dystrophic calcification of cross-linked collagen implants and mineralization during bone induction.
    Calcified tissue international, 1988, Volume: 42, Issue:5

    Topics: Alkaline Phosphatase; Animals; Bone and Bones; Bone Development; Bone Matrix; Calcinosis; Calcium; C

1988
Inhibition of bioprosthetic heart valve calcification with aminodiphosphonate covalently bound to residual aldehyde groups.
    The Annals of thoracic surgery, 1988, Volume: 46, Issue:3

    Topics: Aldehydes; Animals; Aortic Valve Stenosis; Bioprosthesis; Calcinosis; Cattle; Diphosphonates; Diseas

1988
Effect of delay between tissue harvest and glutaraldehyde pretreatment on mineralization of bovine pericardium used in bioprosthetic heart valves.
    Journal of biomedical materials research, 1988, Volume: 22, Issue:9

    Topics: Aldehydes; Animals; Bioprosthesis; Calcinosis; Calcium; Cattle; Glutaral; Heart Valve Prosthesis; Pe

1988