glutaral has been researched along with Asthma in 35 studies
Glutaral: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
glutaraldehyde : A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 46-year-old endoscopy nurse developed symptoms suggestive of occupational asthma after seven years of exposure to glutaraldehyde." | 9.07 | Glutaraldehyde, asthma and work--a cautionary tale. ( Beach, JR; Dennis, JH; Hendrick, DJ; Keaney, NP; Stenton, SC, 1994) |
| "In recent years glutaraldehyde has emerged as the main cause of occupational asthma among healthcare workers." | 8.80 | Occupational asthma due to glutaraldehyde. ( Burge, PS; Di Stefano, F; McCoach, JS; Siriruttanapruk, S, 1998) |
| "Asthma is considered as the most relevant pulmonary disease which is located at bronchial airways and oral theophylline is one of the most prescribed drugs for its treatment as it is inexpensive." | 7.75 | Respiratory delivery of theophylline by size-targeted starch microspheres for treatment of asthma. ( Mohammadi, MH; Momeni, A, 2009) |
| "The purpose of this study was to evaluate bronchoalveolar lavage fluid (BALF) components and Clara cell protein (CC16) concentration in serum and BALF in patients with glutaraldehyde (GA)-induced asthma, before and after a specific inhalatory provocation test (SIPT) with GA, in comparison to atopic asthmatics and healthy individuals." | 7.73 | Glutaraldehyde-induced occupational asthma: BALF components and BALF and serum Clara cell protein (CC16) changes due to specific inhalatory provocation test. ( Gorski, P; Halatek, T; Krakowiak, A; Krawczyk-Adamus, P; Palczynski, C; Ruta, U; Rydzynski, K; Swiercz, R; Walusiak, J; Wittczak, T, 2005) |
| "BACKGROUNDd: Glutaraldehyde (GA) is a known respiratory sensitizers, and some studies have reported occupational asthma in exposed workers." | 7.71 | Occupational asthma and rhinitis due to glutaraldehyde: changes in nasal lavage fluid after specific inhalatory challenge test. ( Górski, P; Pałczyński, C; Ruta, U; Walusiak, J, 2001) |
| "Eight workers were referred for investigation of suspected occupational asthma following direct or indirect exposure to glutaraldehyde at work." | 7.69 | Occupational asthma due to glutaraldehyde and formaldehyde in endoscopy and x ray departments. ( Bright, P; Burge, PS; Campbell, M; Gannon, PF; O'Hickey, SP, 1995) |
| "Occupational asthma can be caused by several sterilizing agents, including glutaraldehyde, which has been shown to cause irritation of the eyes and upper respiratory tract and skin rash." | 7.68 | Occupational asthma in a technologist exposed to glutaraldehyde. ( Catonio-Begley, F; Chan-Yeung, M; Lam, S; McMurren, T, 1993) |
| "A 46-year-old endoscopy nurse developed symptoms suggestive of occupational asthma after seven years of exposure to glutaraldehyde." | 5.07 | Glutaraldehyde, asthma and work--a cautionary tale. ( Beach, JR; Dennis, JH; Hendrick, DJ; Keaney, NP; Stenton, SC, 1994) |
| "In recent years glutaraldehyde has emerged as the main cause of occupational asthma among healthcare workers." | 4.80 | Occupational asthma due to glutaraldehyde. ( Burge, PS; Di Stefano, F; McCoach, JS; Siriruttanapruk, S, 1998) |
| " No previously confirmed formal diagnosis of occupational asthma (OA) caused by hydroxylamine has been made." | 3.75 | Occupational asthma and the paper recycling industry. ( Francis, H; Hoyle, J; Niven, R; Tran, S, 2009) |
| "Asthma is considered as the most relevant pulmonary disease which is located at bronchial airways and oral theophylline is one of the most prescribed drugs for its treatment as it is inexpensive." | 3.75 | Respiratory delivery of theophylline by size-targeted starch microspheres for treatment of asthma. ( Mohammadi, MH; Momeni, A, 2009) |
| "Exposure to glutaraldehyde is a recognized cause of work-related asthma." | 3.74 | Glutaraldehyde exposures among workers making bioprosthetic heart valves. ( Flattery, J; Harrison, R; Materna, B; Prudhomme, J; Quint, J; Sutton, PM, 2007) |
| "A woman developed recurrent episodes of cough, dyspnea, and wheezing unresponsive to asthma therapy after irritant exposure to glutaraldehyde." | 3.73 | Irritant vocal cord dysfunction at first misdiagnosed as reactive airway dysfunction syndrome. ( Bertino, G; Ferrari, M; Galdi, E; Moscato, G; Pagella, F; Perfetti, L, 2005) |
| "The purpose of this study was to evaluate bronchoalveolar lavage fluid (BALF) components and Clara cell protein (CC16) concentration in serum and BALF in patients with glutaraldehyde (GA)-induced asthma, before and after a specific inhalatory provocation test (SIPT) with GA, in comparison to atopic asthmatics and healthy individuals." | 3.73 | Glutaraldehyde-induced occupational asthma: BALF components and BALF and serum Clara cell protein (CC16) changes due to specific inhalatory provocation test. ( Gorski, P; Halatek, T; Krakowiak, A; Krawczyk-Adamus, P; Palczynski, C; Ruta, U; Rydzynski, K; Swiercz, R; Walusiak, J; Wittczak, T, 2005) |
| "Our data suggest that RTs may be at an increased risk for asthma-like symptoms and for receiving a diagnosis of asthma since starting to work in their profession, possibly related to exposure to glutaraldehyde and aerosolized ribavirin." | 3.72 | Respiratory health survey of respiratory therapists. ( Chan-Yeung, M; Dimich-Ward, H; Wymer, ML, 2004) |
| "BACKGROUNDd: Glutaraldehyde (GA) is a known respiratory sensitizers, and some studies have reported occupational asthma in exposed workers." | 3.71 | Occupational asthma and rhinitis due to glutaraldehyde: changes in nasal lavage fluid after specific inhalatory challenge test. ( Górski, P; Pałczyński, C; Ruta, U; Walusiak, J, 2001) |
| "Eight workers were referred for investigation of suspected occupational asthma following direct or indirect exposure to glutaraldehyde at work." | 3.69 | Occupational asthma due to glutaraldehyde and formaldehyde in endoscopy and x ray departments. ( Bright, P; Burge, PS; Campbell, M; Gannon, PF; O'Hickey, SP, 1995) |
| "We describe immunologic responses in subjects exposed to glutaraldehyde (GA) who were diagnosed as having occupational asthma, or who described work-related respiratory symptoms." | 3.69 | Clinical and immunologic evaluation of workers exposed to glutaraldehyde. ( Burge, PS; Curran, AD; Wiley, K, 1996) |
| "Occupational asthma can be caused by several sterilizing agents, including glutaraldehyde, which has been shown to cause irritation of the eyes and upper respiratory tract and skin rash." | 3.68 | Occupational asthma in a technologist exposed to glutaraldehyde. ( Catonio-Begley, F; Chan-Yeung, M; Lam, S; McMurren, T, 1993) |
| " Data from included sources also indicated some evidence for a dose-response relationship regarding increased frequency yielding increased risk, but this relationship is unclear due to potential confounders (differences in role/task and associated exposure) and the healthy worker effect." | 3.01 | Exposure frequency, intensity, and duration: What we know about work-related asthma risks for healthcare workers from cleaning and disinfection. ( Beamer, PI; Fingesi, T; Gerald, LB; Harber, P; Jones, RM; McClelland, DJ; O Ogunseye, O; Wilson, AM, 2023) |
| " Dose-response skin tests were performed at baseline and at the end of the trial." | 2.72 | Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule. ( Colás, C; Lezaun, A; Monzón, S; Venturini, M, 2006) |
| " Dose-response skin prick test with each allergen extract was conducted at baseline and at the end of the study." | 2.71 | Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life. ( Alvarez-Cuesta, E; Aragoneses-Gilsanz, E; Berges-Gimeno, P; Cuesta-Herranz, J; Gonzalez-Mancebo, E; Martín-Garcia, C, 2005) |
| "Glutaraldehyde is an antibacterial and antiviral agent commonly used for cleaning and disinfection of endoscopic equipment." | 2.40 | [Problems of environmental exposure to toxic effects of glutaraldehyde in medicine]. ( Andrzejak, R; Jurga, M; Leszczyszyn, J, 1997) |
| "Isocyanates were the commonest offending agents responsible for 21% of reports followed by metal working fluids (MWFs) (11%), adhesives (7%), chrome (7%), latex (6%) and glutaraldehyde (6%)." | 1.35 | Fifteen-year trends in occupational asthma: data from the Shield surveillance scheme. ( Bakerly, ND; Burge, PS; Jaakkola, MS; Moore, VC; Robertson, AS; Vellore, AD, 2008) |
| "Glutaraldehyde is an irritant and sensitiser." | 1.28 | Occupational hazard in hospital staff exposed to 2 per cent glutaraldehyde in an endoscopy unit. ( Blain, PG; Bound, CL; Jachuck, SJ; Steel, J, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 12 (34.29) | 18.2507 |
| 2000's | 16 (45.71) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Wilson, AM | 1 |
| O Ogunseye, O | 1 |
| Fingesi, T | 1 |
| McClelland, DJ | 1 |
| Gerald, LB | 1 |
| Harber, P | 1 |
| Beamer, PI | 1 |
| Jones, RM | 1 |
| Rosenman, KD | 2 |
| Beckett, WS | 1 |
| Tran, S | 1 |
| Francis, H | 1 |
| Hoyle, J | 1 |
| Niven, R | 1 |
| Momeni, A | 1 |
| Mohammadi, MH | 1 |
| Ong, TH | 1 |
| Tan, KL | 1 |
| Lee, HS | 1 |
| Eng, P | 1 |
| Hamann, CP | 1 |
| Rodgers, PA | 1 |
| Sullivan, KM | 1 |
| Dimich-Ward, H | 1 |
| Wymer, ML | 1 |
| Chan-Yeung, M | 2 |
| Pechter, E | 1 |
| Davis, LK | 1 |
| Tumpowsky, C | 1 |
| Flattery, J | 2 |
| Harrison, R | 2 |
| Reinisch, F | 1 |
| Reilly, MJ | 1 |
| Schill, DP | 1 |
| Valiante, D | 1 |
| Filios, M | 1 |
| Alvarez-Cuesta, E | 1 |
| Aragoneses-Gilsanz, E | 1 |
| Martín-Garcia, C | 1 |
| Berges-Gimeno, P | 1 |
| Gonzalez-Mancebo, E | 1 |
| Cuesta-Herranz, J | 1 |
| Galdi, E | 1 |
| Perfetti, L | 1 |
| Pagella, F | 1 |
| Bertino, G | 1 |
| Ferrari, M | 1 |
| Moscato, G | 1 |
| Palczynski, C | 1 |
| Walusiak, J | 2 |
| Krakowiak, A | 1 |
| Halatek, T | 1 |
| Ruta, U | 2 |
| Krawczyk-Adamus, P | 1 |
| Wittczak, T | 1 |
| Swiercz, R | 1 |
| Gorski, P | 2 |
| Rydzynski, K | 1 |
| Takigawa, T | 1 |
| Endo, Y | 1 |
| Colás, C | 1 |
| Monzón, S | 1 |
| Venturini, M | 1 |
| Lezaun, A | 1 |
| Sutton, PM | 1 |
| Quint, J | 1 |
| Prudhomme, J | 1 |
| Materna, B | 1 |
| Bakerly, ND | 1 |
| Moore, VC | 1 |
| Vellore, AD | 1 |
| Jaakkola, MS | 1 |
| Robertson, AS | 2 |
| Burge, PS | 6 |
| Grzegorczyk, J | 1 |
| Rozniecki, J | 1 |
| Kałła, M | 1 |
| Abbott, L | 1 |
| Gannon, PF | 1 |
| Bright, P | 1 |
| Campbell, M | 2 |
| O'Hickey, SP | 1 |
| Beach, JR | 2 |
| Stenton, SC | 1 |
| Dennis, JH | 1 |
| Keaney, NP | 1 |
| Hendrick, DJ | 1 |
| Stevens, AB | 1 |
| McMurren, T | 1 |
| Catonio-Begley, F | 1 |
| Lam, S | 1 |
| Curran, AD | 1 |
| Wiley, K | 1 |
| Leszczyszyn, J | 1 |
| Andrzejak, R | 1 |
| Jurga, M | 1 |
| Di Stefano, F | 1 |
| Siriruttanapruk, S | 1 |
| McCoach, JS | 1 |
| Quirce, S | 1 |
| Gómez, M | 1 |
| Bombín, C | 1 |
| Sastre, J | 1 |
| Vyas, A | 1 |
| Pickering, CA | 1 |
| Oldham, LA | 1 |
| Francis, HC | 1 |
| Fletcher, AM | 1 |
| Merrett, T | 1 |
| Niven, RM | 1 |
| Anees, W | 1 |
| Pałczyński, C | 1 |
| Cullinan, P | 1 |
| Hayes, J | 1 |
| Cannon, J | 1 |
| Madan, I | 1 |
| Heap, D | 1 |
| Taylor, AN | 1 |
| Kruszewski, J | 1 |
| Jachuck, SJ | 1 |
| Bound, CL | 1 |
| Steel, J | 1 |
| Blain, PG | 1 |
| Corrado, OJ | 1 |
| Osman, J | 1 |
| Davies, RJ | 1 |
| Fal, W | 1 |
| Jankowski, A | 1 |
| Barańska, B | 1 |
| Galary, E | 1 |
| Latoś, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhaled Dose Analysis Using a Breath Actuated Nebulizer in Healthy Subjects[NCT06157515] | 30 participants (Anticipated) | Interventional | 2023-12-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for glutaral and Asthma
| Article | Year |
|---|---|
Exposure frequency, intensity, and duration: What we know about work-related asthma risks for healthcare workers from cleaning and disinfection.
Topics: Asthma; Disinfection; Glutaral; Health Personnel; Humans; Occupational Diseases; Occupational Exposu | 2023 |
Occupational allergens in dentistry.
Topics: Allergens; Asthma; Dentistry; Dermatitis, Allergic Contact; Glutaral; Humans; Hypersensitivity; Late | 2004 |
Effects of glutaraldehyde exposure on human health.
Topics: Adult; Asthma; Drug Hypersensitivity; Endoscopy; Female; Glutaral; Health Personnel; Humans; Japan; | 2006 |
The use and effects of glutaraldehyde: a review.
Topics: Asthma; Dermatitis, Contact; Endoscopy; Glutaral; Humans; Occupational Diseases; Radiography; Steril | 1995 |
[Problems of environmental exposure to toxic effects of glutaraldehyde in medicine].
Topics: Asthma; Cough; Dermatitis, Contact; Endoscopes; Glutaral; Headache; Health Personnel; Humans; Occupa | 1997 |
Occupational asthma due to glutaraldehyde.
Topics: Air Pollutants, Occupational; Asthma; Disinfectants; Glutaral; Health Occupations; Humans; Incidence | 1998 |
3 trials available for glutaral and Asthma
| Article | Year |
|---|---|
Immunotherapy with depigmented glutaraldehyde-polymerized extracts: changes in quality of life.
Topics: Adolescent; Adult; Asthma; Cross-Linking Reagents; Dose-Response Relationship, Immunologic; Double-B | 2005 |
Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule.
Topics: Adolescent; Adult; Allergens; Asthma; Conjunctivitis, Allergic; Desensitization, Immunologic; Double | 2006 |
Glutaraldehyde, asthma and work--a cautionary tale.
Topics: Asthma; Female; Forced Expiratory Volume; Glutaral; Humans; Middle Aged; Nursing; Occupational Disea | 1994 |
26 other studies available for glutaral and Asthma
| Article | Year |
|---|---|
Web based listing of agents associated with new onset work-related asthma.
Topics: Adult; Allergens; Asthma; Databases, Factual; Female; Glutaral; Humans; Internet; Irritants; Middle | 2015 |
Occupational asthma and the paper recycling industry.
Topics: Adult; Asthma; Bronchial Provocation Tests; Glutaral; Histamine; Humans; Hydroxylamine; Male; Occupa | 2009 |
Respiratory delivery of theophylline by size-targeted starch microspheres for treatment of asthma.
Topics: Administration, Inhalation; Asthma; Cross-Linking Reagents; Delayed-Action Preparations; Drug Carrie | 2009 |
A case report of occupational asthma due to gluteraldehyde exposure.
Topics: Adult; Asthma; Bronchial Provocation Tests; Disinfectants; Female; Glutaral; Humans; Inhalation Expo | 2004 |
Respiratory health survey of respiratory therapists.
Topics: Adult; Aerosols; Allied Health Personnel; Asthma; British Columbia; Cross-Sectional Studies; Female; | 2004 |
Work-related asthma among health care workers: surveillance data from California, Massachusetts, Michigan, and New Jersey, 1993-1997.
Topics: Adult; Air Pollutants, Occupational; Asthma; California; Chi-Square Distribution; Detergents; Female | 2005 |
Irritant vocal cord dysfunction at first misdiagnosed as reactive airway dysfunction syndrome.
Topics: Asthma; Cough; Disinfectants; Dyspnea; Female; Glutaral; Humans; Irritants; Laryngeal Diseases; Lary | 2005 |
Glutaraldehyde-induced occupational asthma: BALF components and BALF and serum Clara cell protein (CC16) changes due to specific inhalatory provocation test.
Topics: Adult; Asthma; Basophils; Biomarkers; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cas | 2005 |
Glutaraldehyde exposures among workers making bioprosthetic heart valves.
Topics: Asthma; Bioprosthesis; California; Disinfectants; Female; Glutaral; Heart Valve Prosthesis; Humans; | 2007 |
Fifteen-year trends in occupational asthma: data from the Shield surveillance scheme.
Topics: Adolescent; Adult; Agriculture; Asthma; Delivery of Health Care; England; Female; Glutaral; Humans; | 2008 |
[Leukocyte migration inhibition test in patients with pollen-induced asthma and the results of hyposensitization therapy with Pollinex].
Topics: Allergens; Antigens, Plant; Asthma; Cell Migration Inhibition; Desensitization, Immunologic; Drug Co | 1984 |
Occupational asthma due to glutaraldehyde and formaldehyde in endoscopy and x ray departments.
Topics: Adult; Air Pollutants, Occupational; Asthma; Endoscopy; Female; Formaldehyde; Glutaral; Humans; Male | 1995 |
Occupational exposure to glutaraldehyde.
Topics: Air Pollutants, Occupational; Asthma; Endoscopy; Glutaral; Humans; Occupational Diseases; Occupation | 1994 |
Aldehyde disinfectants and health in endoscopy units.
Topics: Asthma; Endoscopy; Glutaral; Humans; Occupational Diseases; Occupational Health | 1994 |
Occupational asthma in a technologist exposed to glutaraldehyde.
Topics: Adult; Asthma; Female; Follow-Up Studies; Forced Expiratory Volume; Glutaral; Humans; Maximal Expira | 1993 |
Clinical and immunologic evaluation of workers exposed to glutaraldehyde.
Topics: Adult; Albumins; Asthma; False Positive Reactions; Female; Glutaral; Humans; Immunoglobulin E; Male; | 1996 |
Glutaraldehyde-induced asthma.
Topics: Air Pollutants, Occupational; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female | 1999 |
Survey of symptoms, respiratory function, and immunology and their relation to glutaraldehyde and other occupational exposures among endoscopy nursing staff.
Topics: Air Pollutants, Occupational; Asthma; Cross-Sectional Studies; Dermatitis; Disinfectants; Endoscopy; | 2000 |
Glutaraldehyde induced asthma in endoscopy nursing staff.
Topics: Asthma; Disinfectants; Endoscopy; Glutaral; Humans; Nursing; Occupational Diseases; Peak Expiratory | 2001 |
Occupational asthma and rhinitis due to glutaraldehyde: changes in nasal lavage fluid after specific inhalatory challenge test.
Topics: Adult; Albumins; Asthma; Basophils; Blood Proteins; Eosinophil Granule Proteins; Eosinophils; Glutar | 2001 |
Occupational asthma in radiographers.
Topics: Adult; Asthma; Female; Glutaral; Humans; Occupational Diseases; Radiography | 1992 |
[Changes in allergen-specific IgG-4 during desensitization of patients with hay fever and those sensitized to housedust allergens].
Topics: Adult; Air Pollutants; Air Pollution, Indoor; Allergens; Animals; Antigens, Dermatophagoides; Antige | 1991 |
Occupational hazard in hospital staff exposed to 2 per cent glutaraldehyde in an endoscopy unit.
Topics: Aldehydes; Asthma; Dermatitis, Occupational; Endoscopy; Environmental Monitoring; Glutaral; Hospital | 1989 |
Occupational risks of glutaraldehyde.
Topics: Aldehydes; Asthma; Dermatitis, Occupational; Glutaral; Humans; Occupational Diseases | 1989 |
Asthma and rhinitis after exposure to glutaraldehyde in endoscopy units.
Topics: Adult; Airway Resistance; Aldehydes; Asthma; Disinfectants; Endoscopes; Endoscopy; Female; Forced Ex | 1986 |
[Blood basophil histamine and immunoglobulin levels in children with bronchial asthma treated with Pollinex].
Topics: Adolescent; Allergens; Antigens, Plant; Asthma; Basophils; Child; Desensitization, Immunologic; Drug | 1987 |