glutamyl-valyl-glycine has been researched along with Disease-Models--Animal* in 1 studies
1 other study(ies) available for glutamyl-valyl-glycine and Disease-Models--Animal
| Article | Year |
|---|---|
γ-[Glu]n-Trp ameliorates anxiety/depression-like behaviors and its anti-inflammatory effect in an animal model of anxiety/depression.
This study compared the abilities of γ-[Glu]n-Trp (EW) and whey protein hydrolysate (WPH) with a high ratio of Trp : 5 large neutral amino acids (5LNAAs) to reverse chronic restraint stress-corticosterone injection induced anxiety/depression-like behaviors in C57BL/6 male mice. EW was synthesized using l-glutaminase from Bacillus amyloliquefaciens. Acid protease, trypsin, pancreatin or flavorzyme was used to produce WPHs. The WPH with the highest Trp/5LNAAs ratio (17.38%; by trypsin) was selected for animal trials. EW (dose 2.0, 5.0 or 10.0 mg kg Topics: Animals; Anti-Inflammatory Agents; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Hippocampus; Humans; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Prefrontal Cortex; Tryptophan; Tumor Necrosis Factor-alpha; Whey Proteins | 2019 |