Compounds > glutamine

glutamine and Spinocerebellar Ataxias

glutamine has been researched along with Spinocerebellar Ataxias in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (69.23)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Aizawa, Y; Akase, T; Kurasawa, H; Nakane, T; Ohno, T1
Ju, H; Kokubu, H; Lim, J1
Gatchel, JR; Lee, Y; Orr, HT; Samaco, RC; Thaller, C; Zoghbi, HY1
Lichy, C; Müller, U; Nolte, D; Regula, JU; Sobanski, E; Wissen, A1
Orr, HT2
Garcia, JJ; Matilla, A; Opal, P; Orr, HT; Propst, F; Zoghbi, HY1
Chen, S; Grote, SK; La Spada, AR; Peng, GH; Smith, AC; Sopher, BL; Wang, X1
Gomez, CM; Subramony, SH1
Davidson, BL; Eliason, SL; Harper, SQ; Kotin, RM; Mao, Q; Martins, IH; Orr, HT; Paulson, HL; Xia, H; Yang, L1
Caplen, NJ1
Brice, A; Debeir, T; Lasbleiz, C; Latouche, M; Martin, E; Monnier, V; Morel, L; Mouatt-Prigent, A; Muriel, MP; Ruberg, M; Stevanin, G; Tricoire, H1
Orr, HT; Zoghbi, HY1

Reviews

5 review(s) available for glutamine and Spinocerebellar Ataxias

ArticleYear
Beyond the glutamine expansion: influence of posttranslational modifications of ataxin-1 in the pathogenesis of spinocerebellar ataxia type 1.
    Molecular neurobiology, 2014, Volume: 50, Issue:3

    Topics: Ataxin-1; Ataxins; Cerebellum; Glutamine; Humans; Nerve Tissue Proteins; Nuclear Proteins; Protein Processing, Post-Translational; Purkinje Cells; Signal Transduction; Spinocerebellar Ataxias

2014
Polyglutamine neurodegeneration: expanded glutamines enhance native functions.
    Current opinion in genetics & development, 2012, Volume: 22, Issue:3

    Topics: Animals; Autoantigens; Cell Cycle Proteins; Cell Nucleus; Cilia; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Nerve Tissue Proteins; Peptides; Phosphorylation; Receptors, Androgen; Spinocerebellar Ataxias; Structure-Activity Relationship; Trinucleotide Repeat Expansion

2012
Dominantly inherited ataxias.
    Seminars in pediatric neurology, 2003, Volume: 10, Issue:3

    Topics: Genes, Dominant; Glutamine; Humans; Point Mutation; Spinocerebellar Ataxias; Spinocerebellar Degenerations; Trinucleotide Repeat Expansion

2003
Glutamine repeats and neurodegeneration.
    Annual review of neuroscience, 2000, Volume: 23

    Topics: Animals; Glutamine; Humans; Huntington Disease; Muscular Disorders, Atrophic; Neurodegenerative Diseases; Peptides; Repetitive Sequences, Amino Acid; Spinocerebellar Ataxias

2000
Beyond the Qs in the polyglutamine diseases.
    Genes & development, 2001, Apr-15, Volume: 15, Issue:8

    Topics: Cysteine Endopeptidases; Glutamine; Humans; Huntington Disease; Multienzyme Complexes; Mutation; Peptides; Proteasome Endopeptidase Complex; Spinocerebellar Ataxias; Ubiquitins

2001

Other Studies

8 other study(ies) available for glutamine and Spinocerebellar Ataxias

ArticleYear
Development of an isogenic human cell trio that models polyglutamine disease.
    Genes & genetic systems, 2023, Oct-24, Volume: 98, Issue:4

    Topics: Glutamine; Humans; Peptides; Proteins; Spinocerebellar Ataxias

2023
miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis.
    Nature neuroscience, 2008, Volume: 11, Issue:10

    Topics: Animals; Ataxin-1; Ataxins; Cell Line, Transformed; Cerebellum; Disease Models, Animal; Gene Expression Regulation; Glutamine; Green Fluorescent Proteins; Humans; Mice; Mice, Transgenic; MicroRNAs; Nerve Tissue Proteins; Nuclear Proteins; Phenylalanine; Purkinje Cells; RNA, Small Interfering; Spinocerebellar Ataxias; Time Factors; Transfection; Trinucleotide Repeat Expansion

2008
Spinocerebellar ataxia type 17 associated with an expansion of 42 glutamine residues in TATA-box binding protein gene.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:12

    Topics: Adult; Aged; Alleles; Atrophy; Cerebellum; Chromosome Aberrations; Codon; Female; Genes, Dominant; Glutamine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pedigree; Penetrance; Spinocerebellar Ataxias; TATA-Box Binding Protein; Trinucleotide Repeat Expansion; Young Adult

2010
Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis.
    The Journal of biological chemistry, 2003, Sep-05, Volume: 278, Issue:36

    Topics: Animals; Cell Differentiation; Cell Nucleus; Cytoplasm; Glutamine; Humans; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Neurons; Neuropeptides; Nuclear Proteins; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein Transport; Purkinje Cells; Spinocerebellar Ataxias; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques

2003
Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
    Human molecular genetics, 2004, Jan-01, Volume: 13, Issue:1

    Topics: Animals; Ataxin-7; beta-Galactosidase; Blotting, Western; Cell Nucleus; Cells, Cultured; Disease Models, Animal; DNA Primers; Gene Expression Regulation; Genetic Vectors; Glutamine; Homeodomain Proteins; Immunohistochemistry; Luciferases; Mice; Mutagenesis; Nerve Tissue Proteins; Photoreceptor Cells, Vertebrate; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retinal Degeneration; Spinocerebellar Ataxias; Trans-Activators; Transcription, Genetic; Two-Hybrid System Techniques

2004
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.
    Nature medicine, 2004, Volume: 10, Issue:8

    Topics: Adenoviridae; Animals; Ataxin-1; Ataxins; Blotting, Northern; Brain; Cells, Cultured; Disease Models, Animal; Gene Expression; Glutamine; Immunohistochemistry; Mice; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Plasmids; Psychomotor Performance; Purkinje Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spinocerebellar Ataxias; Transduction, Genetic

2004
RNAi quashes polyQ.
    Nature medicine, 2004, Volume: 10, Issue:8

    Topics: Adenoviridae; Animals; Ataxin-1; Ataxins; Brain; Disease Models, Animal; Genetic Vectors; Glutamine; Humans; Mice; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Purkinje Cells; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spinocerebellar Ataxias

2004
A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Mar-07, Volume: 27, Issue:10

    Topics: Animals; Animals, Genetically Modified; Ataxin-7; Cell Death; Cells, Cultured; Disease Models, Animal; Drosophila; Dyskinesias; Glutamine; Humans; Intranuclear Inclusion Bodies; Longevity; Male; Mutation; Nerve Tissue Proteins; Neurons; Peptides; Phenotype; Rats; Spinocerebellar Ataxias; Threonine

2007