Compounds > glutamine

glutamine and Schizophrenia

glutamine has been researched along with Schizophrenia in 128 studies

Research

Studies (128)

TimeframeStudies, this research(%)All Research%
pre-199011 (8.59)18.7374
1990's4 (3.13)18.2507
2000's31 (24.22)29.6817
2010's59 (46.09)24.3611
2020's23 (17.97)2.80

Authors

AuthorsStudies
de la Fuente-Sandoval, C; Graff-Guerrero, A; Honda, S; Hondo, N; Iwata, Y; Kinjo, M; Mimura, M; Mori, Y; Moriguchi, S; Nakahara, K; Nakahara, T; Nakajima, S; Noda, Y; Plitman, E; Segawa, H; Tarumi, R; Tsugawa, S; Uchida, H; Ueno, F; Wada, M; Watanabe, H; Yoshida, K1
Danielmeier, C; Dixon, BJ; Kumar, J1
Chen, X; He, Y; Ma, X; Ouyang, L; Yuan, L; Zheng, W1
Abdullah, M; Chen, KC; Huang, LC; Lin, SH; Tseng, HH; Yang, YK1
Fan, Y; Gao, F; Ma, Q; Ma, X; Wang, C; Wang, W; Wang, Y; Xi, W; Zhao, B; Zhou, L; Zhu, F1
Blazer, A; Calabro, FJ; Ferrarelli, F; Foran, W; Hetherington, HP; Luna, B; Mayeli, A; Perica, M; Sarpal, DK; Sonnenschein, SF; Yushmanov, VE1
Aleman, A; Ashley, S; Beck, K; Block, W; Bloemen, OJN; Borgan, F; Boules, C; Bustillo, JR; Capizzano, AA; Coughlin, JM; David, A; de la Fuente-Sandoval, C; Demjaha, A; Dempster, K; Do, KQ; Du, F; Egerton, A; Falkai, P; Galińska-Skok, B; Gallinat, J; Gasparovic, C; Ginestet, CE; Goto, N; Graff-Guerrero, A; Ho, BC; Howes, O; Jauhar, S; Jeon, P; Kato, T; Kaufmann, CA; Kegeles, LS; Keshavan, MS; Kim, SY; King, B; Kunugi, H; Lauriello, J; León-Ortiz, P; Liemburg, E; McCutcheon, RA; McGuire, P; Mcilwain, ME; Merritt, K; Modinos, G; Mouchlianitis, E; Nakamura, J; Nenadic, I; Öngür, D; Ota, M; Palaniyappan, L; Pantelis, C; Patel, T; Plitman, E; Posporelis, S; Purdon, SE; Reichenbach, JR; Renshaw, PF; Reyes-Madrigal, F; Russell, BR; Sawa, A; Schaefer, M; Shungu, DC; Smesny, S; Stanley, JA; Stone, J; Szulc, A; Taylor, R; Thakkar, KN; Théberge, J; Tibbo, PG; van Amelsvoort, T; Walecki, J; Williamson, PC; Wood, SJ; Xin, L; Yamasue, H1
Garip, B; Kayir, H1
Bless, JJ; Craven, AR; Ersland, L; Grüner, R; Hjelmervik, H; Hugdahl, K; Johnsen, E; Kompus, K; Kroken, RA; Løberg, EM; Sinceviciute, I1
Dechent, P; Ertl-Wagner, B; Falkai, P; Ghaseminejad, F; Hasan, A; Helms, G; Karali, T; Keeser, D; Keller-Varady, K; Malchow, B; Maurus, I; Rauchmann, BS; Schmitt, A; Schneider-Axmann, T; Takahashi, S; Wobrock, T1
Andrews, HF; Baldinger, A; Casadei, S; Fader, KM; Feng, M; Gibbs, RA; Gulsuner, S; Gur, RC; King, MC; Korchina, V; Majara, L; Malan, M; McClellan, JM; Mndini, MM; Mqulwana, SG; Muzny, D; Nagdee, M; Ngqengelele, LL; Ntola, OA; Pretorius, A; Ramesar, RS; Sibeko, G; Stein, DJ; Susser, ES; van der Merwe, C; Walsh, T; Willoughby, E; Zingela, Z1
Benyamina, A; Martelli, C; Petillion, A; Romeo, B1
Gurler, D; Kraguljac, NV; Lahti, AC; Martin, C; Tennant, B; Ver Hoef, L; White, DM1
Bustillo, JR; Gasparovic, C; Jones, T; Lenroot, R; Maudsley, AA; Mayer, EG; Tohen, M; Upston, J1
Kondo, HM; Lin, IF1
Horita, N; Kubota, M; Moriguchi, S; Nakajima, S; Takahata, K1
Haring, L; Kangro, R; Koch, K; Leppik, L; Parksepp, M; Uppin, K; Vasar, E; Zilmer, M1
Andersen, GS; Bojesen, KB; Broberg, BV; Edden, RAE; Fagerlund, B; Glenthøj, BY; Jessen, K; Larsson, HBW; Nielsen, MØ; Rostrup, E; Sigvard, A; Tangmose, K; Thomas, MB1
Fukuda, Y; Heinz, A; Kaminski, J; Katthagen, T; Mascarell-Maricic, L; Schlagenhauf, F1
Avila, A; Barker, GJ; Borgan, F; Chang, N; Egerton, A; Ferreira, D; Gillespie, A; Howes, OD; Lally, J; Lythgoe, DJ; MacCabe, JH; McGuire, P; McQueen, G; Sendt, KV; Stone, JM; Vallianatou, K1
Aleman, A; Block, W; Bloemen, OJN; Borgan, F; Bustillo, JR; Capizzano, AA; Coughlin, JM; De la Fuente-Sandoval, C; Demjaha, A; Dempster, K; Do, KQ; Du, F; Egerton, A; Falkai, P; Galinska-Skok, B; Gallinat, J; Gasparovic, C; Ginestet, CE; Goto, N; Graff-Guerrero, A; Ho, BC; Howes, OD; Jauhar, S; Jeon, P; Kato, T; Kaufmann, CA; Kegeles, LS; Keshavan, M; Kim, SY; Kunugi, H; Lauriello, J; Liemburg, EJ; McGuire, PK; Mcilwain, ME; Merritt, K; Modinos, G; Mouchlianitis, ED; Nakamura, J; Nenadic, I; Öngür, D; Ota, M; Palaniyappan, L; Pantelis, C; Plitman, E; Posporelis, S; Purdon, SE; Reichenbach, JR; Renshaw, PF; Russell, BR; Sawa, A; Schaefer, M; Shungu, DC; Smesny, S; Stanley, JA; Stone, JM; Szulc, A; Taylor, R; Thakkar, K; Théberge, J; Tibbo, PG; van Amelsvoort, T; Walecki, J; Williamson, PC; Wood, SJ; Xin, L; Yamasue, H1
Payani, S; Pradeepkiran, JA; Priya, BL; Venkataramaiah, C1
Carter, CS; Maddock, RJ; Smucny, J1
Aleman, A; Bais, L; Ćurčić-Blake, B; Knegtering, H; Liemburg, E; Pijnenborg, HM; Sibeijn-Kuiper, A1
Chan, Q; Chan, RCK; Cheung, EFC; Chiu, PW; Hung, KSY; Lui, SSY; Mak, HKF; Sham, PC1
Chiappelli, J; Gaston, F; Gaudiot, C; Hong, LE; Kochunov, P; Kodi, P; Quiton, R; Rowland, LM; Shi, Q; Wijtenburg, SA; Wisner, K1
Carlson, M; Carter, CS; Choo, TH; Corlett, PR; Girgis, RR; Grinband, J; Javitt, DC; Kantrowitz, JT; Kegeles, LS; Krystal, JH; Lesh, TA; Lieberman, JA; Maddock, RJ; Mason, G; Potter, WZ; Qiu, M; Ragland, JD; Robinson, J; Rothman, DL; Tanase, C; Wall, MM1
Alshehri, Y; Caravaggio, F; Chakravarty, MM; Chavez, S; Chung, JK; De Luca, V; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Nakajima, S; Plitman, E; Remington, G1
Brookes, MJ; Christodoulou, NG; Fernandes, CC; Fiesal, J; Hall, EL; Katshu, MZ; Kumar, J; Liddle, EB; Liddle, PF; Morris, PG; Palaniyappan, L; Qureshi, A; Robson, SE; Simmonite, M; Skelton, M1
Caravaggio, F; Chavez, S; De Luca, V; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Mar, W; Mimura, M; Nakajima, S; Plitman, E; Remington, G; Shah, P1
Bhakoo, KK; Duytschaever, H; Garnell, JF; Grandjean, J; Sekar, S; Seramani, S; Su, H; Ver Donck, L; Willems, R1
Dwyer, GE; Grüner, R; Hugdahl, K; Specht, K1
Horne, CM; Jelen, LA; King, S; Lythgoe, DJ; Stone, JM; Young, AH1
Bustillo, JR; Chavez, L; Gasparovic, C; Jones, T; Lenroot, RK; Lin, D; Qualls, C1
Araki, T; Fujioka, M; Hashimoto, K; Kasai, K; Kirihara, K; Koike, S; Koshiyama, D; Nagai, T; Suga, M; Tada, M; Usui, K1
Chakravarty, MM; Guma, E; Lepage, M; Near, J; Plitman, E1
Basu, AC; Bolo, NR; Coyle, JT; Konopaske, GT; Renshaw, PF1
Auer, DP; Fone, KC; Napolitano, A; Porkess, V; Schubert, MI; Shah, K1
Avsar, KB; den Hollander, JA; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM1
Bolo, NR; Francis, AN; Keshavan, MS; Mathew, IT; Sanghavi, K; Stanley, JA; Tandon, N1
Abe, O; Aoki, Y; Gonoi, W; Inoue, H; Iwashiro, N; Kasai, K; Katsura, M; Koike, S; Natsubori, T; Sasaki, H; Takano, Y; Takao, H; Yahata, N; Yamasue, H1
Bernstein, HG; Bogerts, B; Dobrowolny, H; Seeleke, P; Steiner, J; Tausch, A; Wagner, R; Walter, M1
Kraguljac, NV; Lahti, AC; Reid, MA; White, DM2
Abbott, C; Bustillo, JR; Canive, J; Chen, H; Gasparovic, C; Jones, T; Lemke, N; Qualls, C1
Hashimoto, K1
Fujimoto, M; Fujita, Y; Hashimoto, K; Hashimoto, R; Ito, A; Numata, S; Ohi, K; Ohmori, T; Takeda, M; Umeda-Yano, S; Yamamori, H; Yasuda, Y1
Anderson, VM; Goldstein, ME; Kydd, RR; Pillai, A; Russell, BR1
Barker, PB; Bonekamp, S; Coughlin, JM; Edden, RA; Higgs, C; Kim, PK; Marsman, A; Pomper, M; Sawa, A; Schretlen, D; Tanaka, T; Varvaris, M; Wang, H1
Abbott, C; Bustillo, JR; Jones, T; Rediske, N; Rowland, LM; Wijtenburg, SA1
Abe, RY; Diniz-Filho, A; Gracitelli, CP; Medeiros, FA; Paranhos, A; Vaz-de-Lima, FB1
Hattori, K; Hori, H; Kunugi, H; Okubo, T; Ota, M; Ozawa, H; Sato, N; Teraishi, T; Wakabayashi, C1
Bargalló, N; Batalla, A; Bernardo, M; Gassó, P; Lafuente, A; Mas, S; Molina, O; Parellada, E; Pareto, D; Roca, JM1
Gawlik-Kotelnicka, O; Gmitrowicz, A; Grzelak, P; Kałużyńska, O; Kotlicka-Antczak, M; Podgórski, M; Stefańczyk, L; Strzelecki, D1
Chavez, S; de la Fuente-Sandoval, C; Gómez-Cruz, G; Graff-Guerrero, A; León-Ortiz, P; Plitman, E; Reyes-Madrigal, F1
Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC1
Egerton, A; Kempton, MJ; McGuire, PK; Merritt, K; Taylor, MJ1
Coyle, JT; Konopaske, G1
Boer, VO; Cahn, W; Kahn, RS; Klomp, DW; Neggers, SF; Rösler, L; Thakkar, KN; Wijnen, JP1
Akhadov, TA; Kaleda, VG; Keshishyan, RA; Lebedeva, IS; Menschikov, PE; Omelchenko, MA; Semenova, NA; Ublinskiy, MV; Varfolomeev, SD1
Abbott, C; Bustillo, JR; Canive, J; Chen, H; Gasparovic, C; Jones, T; Lemke, N; Qualls, C; Stromberg, S1
Chen, H; Chiappelli, J; Du, X; Gaston, FE; Hong, LE; Kochunov, P; Korenic, SA; McMahon, RP; Ndubuizu, N; Rowland, LM; Savransky, A; Wang, DJ; Wijtenburg, SA; Wright, SN1
Cui, H; Li, C; Li, G; Li, Y; Liu, H; Lu, Z; Tang, Y; Wang, J; Xu, L; Zeng, B; Zhang, J; Zhang, T1
Cohen, BM; Jensen, JE; Lundy, M; Öngür, D; Prescot, AP; Renshaw, PF; Stork, C1
Hovorková, P; Klaschka, J; Kozmiková, I; Kristofiková, Z; Majer, E; Rícný, J; Rípová, D; Zach, P1
Fukuda, M; Hashimoto, K; Kasai, K; Kawakubo, Y; Marumo, K; Sasaki, T; Takizawa, R; Tochigi, M1
Brooks, WM; Bustillo, JR; Chen, H; Hammond, R; Jung, R; Lauriello, J; Mullins, P; Qualls, C; Rowland, LM1
Arida, RM; Cavalheiro, EA; Cysneiros, RM; Gattaz, WF; Schmitt, A; Scorza, FA1
Bramon, E; McGuire, PK; Pauls, A; Stone, JM; Sumich, A1
Apfeldorf, W; Bustillo, JR; Caprihan, A; Chen, H; Gasparovic, C; Lauriello, J; Mullins, P; Posse, S; Qualls, C1
Hegde, MV; Saraph, AA1
Azechi, M; Fukumoto, M; Hashimoto, R; Ikezawa, K; Iwase, M; Kamino, K; Kasai, K; Kazui, H; Ohi, K; Takeda, M; Umeda-Yano, S; Yamamori, H; Yasuda, Y1
Aoyama, N; Densmore, M; Drost, DJ; Manchanda, R; Menon, RS; Neufeld, RW; Northcott, S; Pavlosky, WF; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, PC1
Bibulowicz, D; Galinska, B; Konarzewska, B; Poplawska, R; Simonienko, K; Szulc, A; Tarasow, E; Walecki, J; Waszkiewicz, N1
Hulshoff Pol, HE; Kahn, RS; Klomp, DW; Luijten, PR; Marsman, A; van den Heuvel, MP1
Cuenod, M; das Neves Duarte, JM; Do, KQ; Gholam-Razaee, MM; Gruetter, R; Kulak, A1
Feng, S; Li, Z; Lu, B; Shao, L; Shuai, Y; Wang, J; Wang, L; Zhao, Y; Zhong, Y1
Guilarte, TR; Opler, M; Pletnikov, M1
Abi-Dargham, A; Gil, R; Girgis, R; Kegeles, LS; Lisanby, SH; Mao, X; Ojeil, N; Shungu, DC; Slifstein, M; Stanford, AD; Xu, X1
Hattori, K; Hori, H; Ishikawa, M; Kunugi, H; Nakata, Y; Ota, M; Sasayama, D; Sato, N; Teraishi, T1
LoTurco, JJ; Maher, BJ1
Egawa, J; Kaneko, N; Nunokawa, A; Shibuya, M; Someya, T; Watanabe, Y1
Avsar, KB; Bolding, MS; den Hollander, JA; Hutcheson, NL; Knowlton, RC; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM1
Adamski, J; Giegling, I; Hartmann, AM; He, Y; Illig, T; Kahn, R; Li, Y; Prehn, C; Rujescu, D; Wang-Sattler, R; Xie, L; Yu, Z1
Desbonnet, L; O'Tuathaigh, CM; Waddington, JL1
Al-Semaan, Y; Bartha, R; Densmore, M; Drost, DJ; Malla, A; Menon, RS; Neufeld, RW; Pavlosky, W; Rogers, J; Schaefer, B; Takhar, J; Théberge, J; Williamson, PC1
FOSS, OP1
FELIX, WR; KOPIN, IJ; LABROSSE, EH; WESTLAKE, RJ1
Fukuda, R; Fukui, T; Iwanami, A; Kasai, K; Kato, N; Kato, T; Yamasue, H1
Al-Semaan, Y; Densmore, M; Drost, DJ; Menon, RS; Neufeld, RW; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, PC1
Butler, PD; Dulawa, SC; Palmer, AA; Printz, DJ; Printz, MP1
Kishimoto, T; Yoshino, H1
ASTRUP, P; MUNKVAD, I1
Allen, P; Hanstock, C; Tibbo, P; Valiakalayil, A1
Braus, DF; Gallinat, J; Heinz, A; Juckel, G; Puls, I; Romero, B; Weinberger, DR1
Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pfleiderer, B; Siegmund, A; Spitzberg, K; Suslow, T1
Engberg, G; Hashimoto, K; Iyo, M; Lindström, LH; Nordin, C; Shimizu, E1
Bubl, E; Büchert, M; Ebert, D; Hennig, J; Olbrich, HM; Rüsch, N; Thiel, T; Valerius, G; van Elst, LT1
Murck, H; Ploch, M; Schaffler, K; Seibel, K; Spitznagel, H1
Balcar, VJ; Nanitsos, EK; Nguyen, KT; St'astný, F1
Brenner, E; Carlsson, ML; Eyjolfsson, EM; Kondziella, D; Markinhuhta, KR; Sonnewald, U1
Gorman, JM1
Itokawa, M; Yoshikawa, T1
Abbott, C; Bustillo, J1
Chen, J; Lipska, BK; Weinberger, DR1
Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pedersen, A; Pfleiderer, B; Rothermundt, M; Siegmund, A; Spitzberg, K; Suslow, T1
Falkai, P; Maier, W1
Agam, G; Amar, S; Bendikov, I; De Miranda, J; Nadri, C; Panizzutti, R; Wolosker, H1
Andrieux, A; Brenner, E; Nehlig, A; Schweitzer, A; Sonnewald, U1
Chang, L; Davis, K; Ernst, T; Friedman, J; Tsopelas, ND; Zhong, K1
Aoyama, N; Densmore, M; Drost, DJ; Malla, AK; Manchanda, R; Menon, RS; Neufeld, RW; Northcott, S; Pavlosky, W; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, KE; Williamson, PC1
Miüller, N; Schwarz, MJ1
Cahir, M; Harte, MK; Nudmamud-Thanoi, S; Piyabhan, P; Reynolds, GP1
Crow, TJ; DeLisi, LE; Jain, S; Leggo, J; Paykel, ES; Rubinsztein, DC; Walsh, C1
Carr, TJ; Drost, DJ; Malla, A; Rylett, RJ; Stanley, JA; Thompson, RT; Williamson, PC1
Bartha, R; Canaran, G; Carr, TJ; Cortese, L; Drost, DJ; Malla, A; Neufeld, RW; Rylett, RJ; Williamson, PC1
Aoki, J; Arinami, T; Hamaguchi, H; Ishiguro, H; Itokawa, M; Iwawaki, A; Kurumaji, A; Ohtsuki, T; Okubo, Y; Ota, K; Shibuya, H; Shimizu, H; Toru, M1
Deicken, RF; Johnson, C; Pegues, M1
Anjilvel, S; Chan, S; Ellis, SP; Gorman, JM; Kaufmann, CA; Kegeles, LS; Laruelle, M; Malaspina, D; Mann, JJ; Shungu, DC; Xanthopoulos, E1
Lewis, DA; Lieberman, JA1
Alfredsson, G; Wiesel, FA1
Csernansky, JG; Hicks, PB; Riney, SJ; Su, K; Vinogradov, S1
Bunney, BS; Chiodo, LA; Freeman, AS1
Kaufmann, CA; Korpi, ER; Marnela, KM; Weinberger, DR1
Bunney, BS; Charney, DS; Glazer, WM; Heninger, GR; Innis, RB; Price, LH; Rubin, AL; Sternberg, DE1
Greger, J; Hartmann, W; Kluge, H; Wieczorek, V1
Greger, J; Hankowitz, M; Hemke, G; Kluge, H; Wieczorek, V1
Bianchi Porro, G; Maiolo, AT; Negri, VU1

Reviews

26 review(s) available for glutamine and Schizophrenia

ArticleYear
Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of
    Molecular psychiatry, 2022, Volume: 27, Issue:1

    Topics: gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2022
Frontal neural metabolite changes in schizophrenia and their association with cognitive control: A systematic review.
    Neuroscience and biobehavioral reviews, 2022, Volume: 132

    Topics: Brain; Cognition; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Schizophrenia

2022
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis.
    Molecular psychiatry, 2023, Volume: 28, Issue:5

    Topics: Brain; Glutamic Acid; Glutamine; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2023
Magnetic resonance spectroscopy studies in subjects with high risk for psychosis: A meta-analysis and review.
    Journal of psychiatric research, 2020, Volume: 125

    Topics: Aspartic Acid; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia

2020
Treatment effects on neurometabolite levels in schizophrenia: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.
    Schizophrenia research, 2020, Volume: 222

    Topics: Aspartic Acid; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Thalamus

2020
Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data.
    JAMA psychiatry, 2021, 06-01, Volume: 78, Issue:6

    Topics: Adult; Age Factors; Antipsychotic Agents; Biomarkers; Brain; Female; Glutamic Acid; Glutamine; Humans; Male; Patient Acuity; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult

2021
Medial Prefrontal Cortex Glutamate Is Reduced in Schizophrenia and Moderated by Measurement Quality: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies.
    Biological psychiatry, 2021, 11-01, Volume: 90, Issue:9

    Topics: Glutamic Acid; Glutamine; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2021
Current Practice and New Developments in the Use of In Vivo Magnetic Resonance Spectroscopy for the Assessment of Key Metabolites Implicated in the Pathophysiology of Schizophrenia.
    Current topics in medicinal chemistry, 2018, Volume: 18, Issue:21

    Topics: Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Schizophrenia

2018
Using proton magnetic resonance spectroscopic imaging to study glutamatergic alterations in patients with schizophrenia: A systematic review.
    Schizophrenia research, 2019, Volume: 210

    Topics: Brain; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2019
Disruption of glutamate-glutamine-GABA cycle significantly impacts on suicidal behaviour: survey of the literature and own findings on glutamine synthetase.
    CNS & neurological disorders drug targets, 2013, Volume: 12, Issue:7

    Topics: Brain; Case-Control Studies; Cell Count; Female; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Neuroglia; Schizophrenia; Suicide; Synaptic Transmission

2013
Ophthalmology issues in schizophrenia.
    Current psychiatry reports, 2015, Volume: 17, Issue:5

    Topics: Convergence, Ocular; Dopamine; Edinger-Westphal Nucleus; Endophenotypes; Eye Movements; Frontal Lobe; Glutamine; Humans; Neuropsychological Tests; Prefrontal Cortex; Pursuit, Smooth; Quality of Life; Retina; Saccades; Schizophrenia; Visual Pathways; Visual Perception

2015
Thalamic nuclear abnormalities as a contributory factor in sudden cardiac deaths among patients with schizophrenia.
    Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:5

    Topics: Antipsychotic Agents; Aspartic Acid; Death, Sudden, Cardiac; Epilepsy; Glutamine; Humans; Prefrontal Cortex; Schizophrenia; Thalamic Nuclei

2010
Glutamate in schizophrenia: a focused review and meta-analysis of ¹H-MRS studies.
    Schizophrenia bulletin, 2013, Volume: 39, Issue:1

    Topics: Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Schizophrenia

2013
Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses.
    Neurotoxicology, 2012, Volume: 33, Issue:3

    Topics: Age Factors; Animals; Apoptosis; Dopamine; Environmental Exposure; Environmental Pollutants; gamma-Aminobutyric Acid; Gene-Environment Interaction; Glutamine; Humans; Lead; Lead Poisoning, Nervous System; Mutation; Nerve Tissue Proteins; Neurons; Receptors, N-Methyl-D-Aspartate; Risk Assessment; Risk Factors; Schizophrenia; Schizophrenic Psychology

2012
Supportive evidence for the association between the Gln2Pro polymorphism in the SIGMAR1 gene and schizophrenia in the Japanese population: a case-control study and an updated meta-analysis.
    Schizophrenia research, 2012, Volume: 141, Issue:2-3

    Topics: Adult; Asian People; Case-Control Studies; Female; Gene Frequency; Genetic Association Studies; Genotype; Glutamine; Humans; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, sigma; Schizophrenia; Sigma-1 Receptor

2012
Mutant mouse models in evaluating novel approaches to antipsychotic treatment.
    Handbook of experimental pharmacology, 2012, Issue:213

    Topics: Animals; Antipsychotic Agents; Carrier Proteins; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Mice; Nerve Tissue Proteins; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission

2012
[Schizophrenia and sex hormones].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2003, Volume: 105, Issue:11

    Topics: Animals; Dopamine; Estrogens; Glutamine; Humans; Schizophrenia

2003
[Genetic and pharmacological effects on prefrontal cortical function in schizophrenia].
    Der Nervenarzt, 2004, Volume: 75, Issue:9

    Topics: Antipsychotic Agents; Dopamine; Genotype; Glutamine; Humans; Limbic System; Nerve Net; Neuropsychological Tests; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Temporal Lobe; Treatment Outcome

2004
Glutamatergic hypothesis of schizophrenia: involvement of Na+/K+-dependent glutamate transport.
    Journal of biomedical science, 2005, Volume: 12, Issue:6

    Topics: Animals; Biological Transport; Central Nervous System; Gene Expression Regulation, Enzymologic; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamic Acid; Glutamine; Humans; Models, Biological; Neurotransmitter Agents; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; Sodium-Potassium-Exchanging ATPase; Synapses

2005
[Susceptibility genes for schizophrenia].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 12

    Topics: Animals; Carrier Proteins; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Genetic Linkage; Genetic Predisposition to Disease; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Nerve Tissue Proteins; Neuregulin-1; Polymorphism, Single Nucleotide; Schizophrenia

2005
What have we learned from proton magnetic resonance spectroscopy about schizophrenia? A critical update.
    Current opinion in psychiatry, 2006, Volume: 19, Issue:2

    Topics: Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Cross-Over Studies; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Protons; Schizophrenia; Temporal Lobe

2006
Genetic mouse models of schizophrenia: from hypothesis-based to susceptibility gene-based models.
    Biological psychiatry, 2006, Jun-15, Volume: 59, Issue:12

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Genetic Predisposition to Disease; Glutamine; Mice; Models, Genetic; Schizophrenia

2006
[Advances in neurobiological understanding of schizophrenia. Perspectives for new therapeutic concepts].
    Der Nervenarzt, 2006, Volume: 77 Suppl 2

    Topics: Animals; Aspartic Acid; Brain; Carrier Proteins; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Neuregulin-1; Neurons; Neuropil; Risk Factors; Schizophrenia; Synaptic Transmission

2006
The immunological basis of glutamatergic disturbance in schizophrenia: towards an integrated view.
    Journal of neural transmission. Supplementum, 2007, Issue:72

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Brain; Carrier Proteins; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Neuregulins; Psychoneuroimmunology; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Tryptophan; Tryptophan Oxygenase

2007
Proton magnetic resonance spectroscopy of the human brain in schizophrenia.
    Reviews in the neurosciences, 2000, Volume: 11, Issue:2-3

    Topics: Aspartic Acid; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Protons; Schizophrenia

2000
Catching up on schizophrenia: natural history and neurobiology.
    Neuron, 2000, Volume: 28, Issue:2

    Topics: Antipsychotic Agents; Behavioral Symptoms; Brain; Cognition Disorders; Delusions; Dopamine; Female; Glutamine; Hallucinations; Humans; Male; Neural Pathways; Psychotherapy; Schizophrenia; Synaptic Transmission

2000

Trials

8 trial(s) available for glutamine and Schizophrenia

ArticleYear
Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial.
    JAMA psychiatry, 2018, 01-01, Volume: 75, Issue:1

    Topics: Adult; Antipsychotic Agents; Biomarkers; Brain; Drug Development; Female; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance Imaging; Male; Middle Aged; Molecular Targeted Therapy; Neuroimaging; Oxygen; Psychotic Disorders; Receptors, Glutamate; Schizophrenia; Young Adult

2018
Effect of L-theanine on glutamatergic function in patients with schizophrenia.
    Acta neuropsychiatrica, 2015, Volume: 27, Issue:5

    Topics: Adult; Antipsychotic Agents; Brain; Case-Control Studies; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Sleep; Treatment Outcome

2015
Supplementation of antipsychotic treatment with sarcosine – GlyT1 inhibitor – causes changes of glutamatergic (1)NMR spectroscopy parameters in the left hippocampus in patients with stable schizophrenia.
    Neuroscience letters, 2015, Oct-08, Volume: 606

    Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Double-Blind Method; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Humans; Inositol; Male; Middle Aged; Sarcosine; Schizophrenia; Young Adult

2015
Proton magnetic resonance spectroscopy study of brain metabolite changes after antipsychotic treatment.
    Pharmacopsychiatry, 2011, Volume: 44, Issue:4

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Brain Chemistry; Diagnostic and Statistical Manual of Mental Disorders; Female; Follow-Up Studies; Fourier Analysis; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Schizophrenia; Thalamus; Young Adult

2011
Hypericum extract reverses S-ketamine-induced changes in auditory evoked potentials in humans - possible implications for the treatment of schizophrenia.
    Biological psychiatry, 2006, Mar-01, Volume: 59, Issue:5

    Topics: Adult; Cognition Disorders; Cross-Over Studies; Double-Blind Method; Evoked Potentials, Auditory; Female; Glutamine; Humans; Hypericum; Ketamine; Male; Middle Aged; Neuropsychological Tests; Phytotherapy; Plant Extracts; Schizophrenia; Schizophrenic Psychology

2006
Monoamine metabolites and amino acids in serum from schizophrenic patients before and during sulpiride treatment.
    Psychopharmacology, 1989, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Biogenic Monoamines; Female; Glutamates; Glutamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Meglutol; Schizophrenia; Sulpiride; Tryptophan; Tyrosine

1989
A preliminary dose-ranging trial of proglumide for the treatment of refractory schizophrenics.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:3

    Topics: Antipsychotic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Glutamine; Humans; Proglumide; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1989
Does the cholecystokinin antagonist proglumide possess antipsychotic activity?
    Psychiatry research, 1986, Volume: 18, Issue:1

    Topics: Adult; Cholecystokinin; Female; Glutamine; Humans; Pilot Projects; Proglumide; Schizophrenia

1986

Other Studies

94 other study(ies) available for glutamine and Schizophrenia

ArticleYear
Abnormal neurobiochemical metabolites in the first
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021, Oct-28, Volume: 46, Issue:10

    Topics: Aspartic Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2021
Altered glutamate level and its association with working memory among patients with treatment-resistant schizophrenia (TRS): a proton magnetic resonance spectroscopy study.
    Psychological medicine, 2023, Volume: 53, Issue:7

    Topics: Adult; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Memory, Short-Term; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenia, Treatment-Resistant

2023
Characterizing serum amino acids in schizophrenic patients: Correlations with gut microbes.
    Journal of psychiatric research, 2022, Volume: 153

    Topics: Amino Acids; Arginine; Gastrointestinal Microbiome; Glutamine; Humans; Leucine; Methionine; Schizophrenia

2022
A longitudinal investigation of GABA, glutamate, and glutamine across the insula during antipsychotic treatment of first-episode schizophrenia.
    Schizophrenia research, 2022, Volume: 248

    Topics: Antipsychotic Agents; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Schizophrenia

2022
Alteration in NMDAR-related amino acids in first episode psychosis.
    Synapse (New York, N.Y.), 2019, Volume: 73, Issue:11

    Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult

2019
Intra-Regional Glu-GABA vs Inter-Regional Glu-Glu Imbalance: A 1H-MRS Study of the Neurochemistry of Auditory Verbal Hallucinations in Schizophrenia.
    Schizophrenia bulletin, 2020, 04-10, Volume: 46, Issue:3

    Topics: Adult; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Hallucinations; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe

2020
The impact of endurance training and table soccer on brain metabolites in schizophrenia.
    Brain imaging and behavior, 2020, Volume: 14, Issue:2

    Topics: Adult; Aspartic Acid; Brain; Cognition; Creatine; Endurance Training; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inpatients; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Schizophrenia; Thalamus

2020
Genetics of schizophrenia in the South African Xhosa.
    Science (New York, N.Y.), 2020, 01-31, Volume: 367, Issue:6477

    Topics: Age Factors; Autistic Disorder; Bipolar Disorder; Dopamine; Female; gamma-Aminobutyric Acid; Genetic Variation; Glutamine; Humans; Male; Mutation; Neural Pathways; Schizophrenia; Sex Factors; South Africa; Synapses; Synaptic Transmission

2020
Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic Treatment.
    Neuropsychobiology, 2021, Volume: 80, Issue:1

    Topics: Adult; Antipsychotic Agents; Cognitive Dysfunction; Default Mode Network; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory; Memory, Episodic; Mental Recall; Proton Magnetic Resonance Spectroscopy; Recognition, Psychology; Risperidone; Schizophrenia; Treatment Outcome; Young Adult

2021
Glutamatergic hypo-function in the left superior and middle temporal gyri in early schizophrenia: a data-driven three-dimensional proton spectroscopic imaging study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:11

    Topics: Aspartic Acid; Creatine; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Protons; Schizophrenia

2020
Excitation-inhibition balance and auditory multistable perception are correlated with autistic traits and schizotypy in a non-clinical population.
    Scientific reports, 2020, 05-18, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Auditory Cortex; Auditory Perception; Autism Spectrum Disorder; Child; Female; Glutamic Acid; Glutamine; Humans; Inhibition, Psychological; Male; Schizophrenia; Schizotypal Personality Disorder; Verbal Learning; Young Adult

2020
Metabolomics approach revealed robust changes in amino acid and biogenic amine signatures in patients with schizophrenia in the early course of the disease.
    Scientific reports, 2020, 08-19, Volume: 10, Issue:1

    Topics: Adult; Amino Acids; Antipsychotic Agents; Asparagine; Aspartic Acid; Biogenic Amines; Chromatography, Liquid; Early Diagnosis; Female; Glutamic Acid; Glutamine; Humans; Male; Metabolome; Metabolomics; Proline; Schizophrenia; Tandem Mass Spectrometry; Taurine; Young Adult

2020
Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis.
    Biological psychiatry, 2021, 02-01, Volume: 89, Issue:3

    Topics: Antipsychotic Agents; Cognition; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Psychotic Disorders; Schizophrenia

2021
Glutamate in the Dorsolateral Prefrontal Cortex in Patients With Schizophrenia: A Meta-analysis of
    Biological psychiatry, 2021, 02-01, Volume: 89, Issue:3

    Topics: Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2021
Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia.
    Schizophrenia bulletin, 2021, 04-29, Volume: 47, Issue:3

    Topics: Adult; Antipsychotic Agents; Caudate Nucleus; Clozapine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Longitudinal Studies; Male; Middle Aged; Outcome Assessment, Health Care; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2021
Therapeutic potentiality of a new flavonoid against ketamine induced glutamatergic dysregulation in schizophrenia: In vivo and in silico approach.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 138

    Topics: Animals; Antipsychotic Agents; Brain; Celastrus; Flavonoids; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Ketamine; Male; Molecular Docking Simulation; Neuroprotective Agents; Rats, Wistar; Schizophrenia

2021
Glutamate in dorsolateral prefrontal cortex and auditory verbal hallucinations in patients with schizophrenia: A
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 08-01, Volume: 78

    Topics: Adult; Case-Control Studies; Female; Glutamic Acid; Glutamine; Hallucinations; Humans; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult

2017
In vivo gamma-aminobutyric acid and glutamate levels in people with first-episode schizophrenia: A proton magnetic resonance spectroscopy study.
    Schizophrenia research, 2018, Volume: 193

    Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Glutamine; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; ROC Curve; Schizophrenia; Young Adult

2018
Glutamatergic Response to Heat Pain Stress in Schizophrenia.
    Schizophrenia bulletin, 2018, 06-06, Volume: 44, Issue:4

    Topics: Adult; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hot Temperature; Humans; Male; Middle Aged; Nociceptive Pain; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Stress, Physiological; Young Adult

2018
Striatal neurometabolite levels in patients with schizophrenia undergoing long-term antipsychotic treatment: A proton magnetic resonance spectroscopy and reliability study.
    Psychiatry research. Neuroimaging, 2018, 03-30, Volume: 273

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Schizophrenia

2018
Glutathione and glutamate in schizophrenia: a 7T MRS study.
    Molecular psychiatry, 2020, Volume: 25, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2020
Glutamatergic Neurometabolite Levels in Patients With Ultra-Treatment-Resistant Schizophrenia: A Cross-Sectional 3T Proton Magnetic Resonance Spectroscopy Study.
    Biological psychiatry, 2019, 04-01, Volume: 85, Issue:7

    Topics: Adult; Antipsychotic Agents; Caudate Nucleus; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2019
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Memantine; Motor Activity; Rats; Rats, Wistar; Schizophrenia; Stress, Psychological; Sucrose; Taurine

2019
Functional magnetic resonance spectroscopy in patients with schizophrenia and bipolar affective disorder: Glutamate dynamics in the anterior cingulate cortex during a working memory task.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019, Volume: 29, Issue:2

    Topics: Adult; Analysis of Variance; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Schizophrenia; Young Adult

2019
Proton magnetic resonance spectroscopic imaging of gray and white matter in bipolar-I and schizophrenia.
    Journal of affective disorders, 2019, 03-01, Volume: 246

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult

2019
Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study.
    Schizophrenia research, 2019, Volume: 208

    Topics: Adolescent; Adult; Case-Control Studies; Electroencephalography; Evoked Potentials, Auditory; Female; GABAergic Neurons; Gamma Rhythm; Glutamic Acid; Glutamine; Glycine; Humans; Male; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult

2019
Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain.
    Psychopharmacology, 2013, Volume: 230, Issue:1

    Topics: Animals; Antipsychotic Agents; Astrocytes; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Haloperidol; Homeostasis; Magnetic Resonance Spectroscopy; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Schizophrenia; Time Factors

2013
In vivo neurometabolic profiling to characterize the effects of social isolation and ketamine-induced NMDA antagonism: a rodent study at 7.0 T.
    Schizophrenia bulletin, 2014, Volume: 40, Issue:3

    Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Ketamine; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Social Isolation

2014
Proton magnetic resonance spectroscopy of the substantia nigra in schizophrenia.
    Schizophrenia research, 2013, Volume: 147, Issue:2-3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Protons; Schizophrenia; Substantia Nigra; Young Adult

2013
Brain metabolite alterations in young adults at familial high risk for schizophrenia using proton magnetic resonance spectroscopy.
    Schizophrenia research, 2013, Volume: 148, Issue:1-3

    Topics: Adolescent; Analysis of Variance; Aspartic Acid; Brain; Cognition Disorders; Family Health; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Young Adult

2013
Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia.
    Schizophrenia bulletin, 2014, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Chronic Disease; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prodromal Symptoms; Psychotic Disorders; Risk; Schizophrenia; Young Adult

2014
Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia.
    JAMA psychiatry, 2013, Volume: 70, Issue:12

    Topics: Adult; Aspartic Acid; Biomarkers; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multimodal Imaging; Schizophrenia; Young Adult

2013
Increased glutamine in patients undergoing long-term treatment for schizophrenia: a proton magnetic resonance spectroscopy study at 3 T.
    JAMA psychiatry, 2014, Volume: 71, Issue:3

    Topics: Adult; Choline; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Severity of Illness Index; Time Factors

2014
Abnormalities of the glutamine-glutamate-GABA cycle in the schizophrenia brain.
    Schizophrenia research, 2014, Volume: 156, Issue:2-3

    Topics: Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia

2014
Changes in plasma D-serine, L-serine, and glycine levels in treatment-resistant schizophrenia before and after clozapine treatment.
    Neuroscience letters, 2014, Oct-17, Volume: 582

    Topics: Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Schizophrenia; Serine; Stereoisomerism; Treatment Failure

2014
Glutamatergic neurometabolites in clozapine-responsive and -resistant schizophrenia.
    The international journal of neuropsychopharmacology, 2015, Jan-20, Volume: 18, Issue:6

    Topics: Adult; Antipsychotic Agents; Biomarkers; Brain; Case-Control Studies; Clozapine; Creatine; Drug Resistance; Drug Therapy, Combination; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult

2015
Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia.
    Current molecular medicine, 2015, Volume: 15, Issue:2

    Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Neuropsychological Tests; Oxidative Stress; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia

2015
Reproducibility of phase rotation stimulated echo acquisition mode at 3T in schizophrenia: Emphasis on glutamine.
    Magnetic resonance in medicine, 2016, Volume: 75, Issue:2

    Topics: Adult; Brain Chemistry; Female; Glutamine; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Reproducibility of Results; Schizophrenia

2016
Apoptotic markers in cultured fibroblasts correlate with brain metabolites and regional brain volume in antipsychotic-naive first-episode schizophrenia and healthy controls.
    Translational psychiatry, 2015, Aug-25, Volume: 5

    Topics: Adult; Apoptosis; Brain; Caspase 3; Cell Culture Techniques; Female; Fibroblasts; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Organ Size; Schizophrenia; Young Adult

2015
Elevated Myo-Inositol, Choline, and Glutamate Levels in the Associative Striatum of Antipsychotic-Naive Patients With First-Episode Psychosis: A Proton Magnetic Resonance Spectroscopy Study With Implications for Glial Dysfunction.
    Schizophrenia bulletin, 2016, Volume: 42, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Corpus Striatum; Glutamic Acid; Glutamine; Humans; Inositol; Neuroglia; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia

2016
A combined diffusion tensor imaging and magnetic resonance spectroscopy study of patients with schizophrenia.
    Schizophrenia research, 2016, Volume: 170, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Creatine; Diffusion Tensor Imaging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Multimodal Imaging; Myelin Sheath; Psychotic Disorders; Schizophrenia; White Matter

2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
    Schizophrenia research, 2016, Volume: 172, Issue:1-3

    Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia

2016
Nature of Glutamate Alterations in Schizophrenia: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies.
    JAMA psychiatry, 2016, 07-01, Volume: 73, Issue:7

    Topics: Brain; Brain Mapping; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Reference Values; Risk Factors; Schizophrenia; Synaptic Transmission

2016
Glutamatergic Dysfunction in Schizophrenia Evaluated With Magnetic Resonance Spectroscopy.
    JAMA psychiatry, 2016, 07-01, Volume: 73, Issue:7

    Topics: Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Schizophrenia

2016
7T Proton Magnetic Resonance Spectroscopy of Gamma-Aminobutyric Acid, Glutamate, and Glutamine Reveals Altered Concentrations in Patients With Schizophrenia and Healthy Siblings.
    Biological psychiatry, 2017, 03-15, Volume: 81, Issue:6

    Topics: Adult; Brain; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Siblings

2017
(1)H-MRS and MEGA-PRESS pulse sequence in the study of balance of inhibitory and excitatory neurotransmitters in the human brain of ultra-high risk of schizophrenia patients.
    Doklady. Biochemistry and biophysics, 2016, Volume: 468, Issue:1

    Topics: Adolescent; Adult; Creatine; Frontal Lobe; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Risk; Schizophrenia; Young Adult

2016
Glutamatergic and Neuronal Dysfunction in Gray and White Matter: A Spectroscopic Imaging Study in a Large Schizophrenia Sample.
    Schizophrenia bulletin, 2017, 05-01, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult

2017
Altered Glutamate and Regional Cerebral Blood Flow Levels in Schizophrenia: A
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenic Psychology; White Matter; Young Adult

2017
Reduced
    Neural plasticity, 2016, Volume: 2016

    Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Risk; Schizophrenia; Young Adult

2016
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania.
    Biological psychiatry, 2008, Oct-15, Volume: 64, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult

2008
Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia.
    Neurochemistry international, 2008, Volume: 53, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Citrulline; Dementia, Multi-Infarct; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Isoenzymes; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Schizophrenia; Signal Transduction

2008
Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Apr-30, Volume: 33, Issue:3

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Brain Mapping; Chi-Square Distribution; Chlorpromazine; Cognition; Female; Genotype; Glutamine; Hemodynamics; Humans; Male; Middle Aged; Neuropsychological Tests; Oxyhemoglobins; Polymorphism, Genetic; Prefrontal Cortex; Proline; Receptors, sigma; Schizophrenia; Sigma-1 Receptor; Spectroscopy, Near-Infrared; Verbal Behavior

2009
1H-MRS at 4 tesla in minimally treated early schizophrenia.
    Molecular psychiatry, 2010, Volume: 15, Issue:6

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Female; Frontal Lobe; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Protons; Schizophrenia; Thalamus; Time Factors

2010
Thalamic neurochemical abnormalities in individuals with prodromal symptoms of schizophrenia - relationship to auditory event-related potentials.
    Psychiatry research, 2010, Aug-30, Volume: 183, Issue:2

    Topics: Acoustic Stimulation; Adult; Aspartic Acid; Electroencephalography; Evoked Potentials, Auditory; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Neurochemistry; Protons; Radionuclide Imaging; Schizophrenia; Thalamus; Young Adult

2010
Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla.
    Biological psychiatry, 2011, Jan-01, Volume: 69, Issue:1

    Topics: Adult; Age Factors; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuropsychological Tests; Protons; Schizophrenia; Schizophrenic Psychology

2011
Unstable genes unstable mind: beyond the central dogma of molecular biology.
    Medical hypotheses, 2011, Volume: 77, Issue:2

    Topics: Anticipation, Genetic; Gene Expression Regulation; Glutamine; Humans; Models, Neurological; Schizophrenia; Trinucleotide Repeat Expansion

2011
The SIGMAR1 gene is associated with a risk of schizophrenia and activation of the prefrontal cortex.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jul-01, Volume: 35, Issue:5

    Topics: Adult; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Male; Meta-Analysis as Topic; Middle Aged; Polymorphism, Single Nucleotide; Prefrontal Cortex; Proline; Receptors, sigma; Schizophrenia; Sigma-1 Receptor; Spectroscopy, Near-Infrared; Speech Disorders

2011
Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia.
    The British journal of psychiatry : the journal of mental science, 2011, Volume: 198, Issue:6

    Topics: Activities of Daily Living; Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Brain Mapping; Case-Control Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Participation; Thalamus; Time Factors

2011
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
    Biological psychiatry, 2012, Jun-01, Volume: 71, Issue:11

    Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia

2012
Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Nov-15, Volume: 108, Issue:46

    Topics: Animals; Carrier Proteins; DNA-Binding Proteins; Dopamine; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Dysbindin; Dystrophin-Associated Proteins; Genetic Predisposition to Disease; Glutamine; Humans; Models, Biological; Mutation; Neurons; Neurotransmitter Agents; Schizophrenia; Tissue Distribution

2011
Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy.
    Archives of general psychiatry, 2012, Volume: 69, Issue:5

    Topics: Adult; Case-Control Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Neuroimaging; Prefrontal Cortex; Schizophrenia

2012
Glutamatergic changes in the cerebral white matter associated with schizophrenic exacerbation.
    Acta psychiatrica Scandinavica, 2012, Volume: 126, Issue:1

    Topics: Adult; Brain; Brain Chemistry; Case-Control Studies; Disease Progression; Excitatory Amino Acids; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroimaging; Parietal Lobe; Schizophrenia

2012
Disrupted-in-schizophrenia (DISC1) functions presynaptically at glutamatergic synapses.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Animals; Brain; Electrophysiology; Gene Expression Regulation; Genetic Variation; Glutamine; Kinetics; Models, Biological; Nerve Tissue Proteins; Neurons; Plasmids; Rats; Rats, Wistar; RNA Interference; Schizophrenia; Synapses; Synaptic Transmission; Transgenes

2012
Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging.
    Schizophrenia research, 2012, Volume: 140, Issue:1-3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxygen; Protons; Schizophrenia; Young Adult

2012
Schizophrenia shows a unique metabolomics signature in plasma.
    Translational psychiatry, 2012, Aug-14, Volume: 2

    Topics: Adult; Aged; Analysis of Variance; Antipsychotic Agents; Arginine; Biomarkers; Case-Control Studies; Female; Genetic Markers; Genetic Predisposition to Disease; Genome-Wide Association Study; Glutamine; Humans; Least-Squares Analysis; Logistic Models; Male; Mass Spectrometry; Metabolomics; Middle Aged; Schizophrenia

2012
Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers.
    The American journal of psychiatry, 2002, Volume: 159, Issue:11

    Topics: Adult; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Schizophrenic Psychology; Thalamus

2002
The urinary excretion of glutamine and glutamic acid in normals and in a group of psychiatric patients.
    Scandinavian journal of clinical and laboratory investigation, 1954, Volume: 6, Issue:2

    Topics: Glutamates; Glutamic Acid; Glutamine; Humans; Schizophrenia; Urine

1954
URINARY TRYPTAMINE AND INDOLE-3-ACETIC ACID EXCRETION BY SCHIZOPHRENIC PATIENTS: USE OF THE TRYPTAMINE/INDOLE ACETIC ACID RATIO AS AN INDEX OF MONOAMINE OXIDASE INHIBITION.
    Journal of psychiatric research, 1964, Volume: 2

    Topics: Amino Acids; Fluids and Secretions; Glutamine; Glycine; Histidine; Humans; Indoleacetic Acids; Indoles; Iproniazid; Metabolism; Methionine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pharmacology; Phenylalanine; Schizophrenia; Tryptamines; Tryptophan; Urine

1964
Drug-induced parkinsonism in relation to choline-containing compounds measured by 1H-MR spectroscopy in putamen of chronically medicated patients with schizophrenia.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:4

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia Diseases; Choline; Chronic Disease; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurologic Examination; Parkinson Disease, Secondary; Phosphocreatine; Putamen; Reference Values; Schizophrenia; Schizophrenic Psychology

2003
Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS.
    The American journal of psychiatry, 2003, Volume: 160, Issue:12

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Thalamus

2003
Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding.
    Brain research, 2004, Jan-23, Volume: 996, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Dopamine; Female; Fetus; Glutamine; Male; Neural Inhibition; Pregnancy; Prenatal Nutritional Physiological Phenomena; Protein Deficiency; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Sex Factors; Time Factors

2004
[Glutamine and glutamic acid metabolism, with special reference to nervous tissue and psychiatric disease].
    Nordisk medicin, 1951, Jan-24, Volume: 45, Issue:4

    Topics: Glutamic Acid; Glutamine; Humans; Nerve Tissue; Psychotic Disorders; Schizophrenia

1951
3-T proton MRS investigation of glutamate and glutamine in adolescents at high genetic risk for schizophrenia.
    The American journal of psychiatry, 2004, Volume: 161, Issue:6

    Topics: Adolescent; Child of Impaired Parents; Cohort Studies; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Social Class

2004
Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study.
    Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3

    Topics: Adult; Aspartic Acid; Chronic Disease; Diagnostic and Statistical Manual of Mental Disorders; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Protons; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Synaptic Transmission

2005
Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients.
    BMC psychiatry, 2005, Jan-31, Volume: 5

    Topics: Adolescent; Adult; Brain Chemistry; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Humans; Male; Reference Values; Schizophrenia

2005
Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study.
    Biological psychiatry, 2005, Nov-01, Volume: 58, Issue:9

    Topics: Adult; Analysis of Variance; Chronic Disease; Electroencephalography; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Synapses

2005
Glial-neuronal interactions are impaired in the schizophrenia model of repeated MK801 exposure.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:9

    Topics: Acetates; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Glucose; Glutamic Acid; Glutamine; Isotope Labeling; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Schizophrenia

2006
Glutamine: ubiquitous and overlooked.
    CNS spectrums, 2005, Volume: 10, Issue:10

    Topics: Animals; Brain; Glutamine; Humans; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission

2005
Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study.
    Journal of psychiatric research, 2007, Volume: 41, Issue:8

    Topics: Adult; Aged; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Cognition Disorders; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Recall; Middle Aged; Neurons; Phosphocreatine; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Verbal Learning

2007
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia.
    Schizophrenia research, 2007, Volume: 90, Issue:1-3

    Topics: Adolescent; Adult; Aged; Brain; D-Amino-Acid Oxidase; Female; Frontal Lobe; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Middle Aged; Parietal Lobe; Racemases and Epimerases; Reference Values; Schizophrenia; Serine

2007
Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia.
    Journal of neuroscience research, 2007, Nov-15, Volume: 85, Issue:15

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Dopamine; Energy Metabolism; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neurons; Schizophrenia; Synaptic Vesicles

2007
Brain metabolite abnormalities in the white matter of elderly schizophrenic subjects: implication for glial dysfunction.
    Biological psychiatry, 2007, Dec-15, Volume: 62, Issue:12

    Topics: Aged; Alanine; Brain; Brain Mapping; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Protons; Schizophrenia

2007
Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia.
    The British journal of psychiatry : the journal of mental science, 2007, Volume: 191

    Topics: Adult; Case-Control Studies; Female; Functional Laterality; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Thalamus; Time Factors

2007
Deficits of neuronal glutamatergic markers in the caudate nucleus in schizophrenia.
    Journal of neural transmission. Supplementum, 2007, Issue:72

    Topics: Adult; Animals; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Transporter 3; Female; Glutamine; Humans; Long-Term Care; Male; Middle Aged; Neural Pathways; Rats; Rats, Sprague-Dawley; Schizophrenia; Synaptic Transmission; Vesicular Glutamate Transport Protein 1

2007
Analysis of polyglutamine-coding repeats in the TATA-binding protein in different human populations and in patients with schizophrenia and bipolar affective disorder.
    American journal of medical genetics, 1996, Sep-20, Volume: 67, Issue:5

    Topics: Africa; Bipolar Disorder; Cerebellar Ataxia; DNA-Binding Proteins; England; Ethnicity; Glutamine; Humans; Huntington Disease; India; Muscular Atrophy, Spinal; Peptides; Polymorphism, Genetic; Racial Groups; Schizophrenia; TATA-Box Binding Protein; Transcription Factors; Trinucleotide Repeats

1996
An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients.
    Schizophrenia bulletin, 1996, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1996
Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy.
    Archives of general psychiatry, 1997, Volume: 54, Issue:10

    Topics: Adolescent; Adult; Aspartic Acid; Educational Status; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Schizophrenia; Sex Factors; Tomography, Emission-Computed

1997
Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia.
    Neuroscience letters, 1998, Nov-20, Volume: 257, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; DNA Primers; Female; Gene Frequency; Genetic Linkage; Glutamine; Humans; Japan; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Receptors, sigma; Schizophrenia

1998
Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies.
    Psychiatry research, 2000, May-15, Volume: 98, Issue:3

    Topics: Adult; Aspartic Acid; Case-Control Studies; Dominance, Cerebral; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia

2000
Further studies on the specificity of proglumide as a selective cholecystokinin antagonist in the central nervous system.
    Annals of the New York Academy of Sciences, 1985, Volume: 448

    Topics: Animals; Anorexia Nervosa; Antipsychotic Agents; Apomorphine; Brain; Cholecystokinin; Glutamine; Humans; Mesencephalon; Neurons; Proglumide; Receptors, Dopamine; Schizophrenia

1985
Cerebrospinal fluid amino acid concentrations in chronic schizophrenia.
    Psychiatry research, 1987, Volume: 20, Issue:4

    Topics: Adult; Aged; Alanine; Amino Acids; Chronic Disease; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Schizophrenia; Taurine

1987
[Course studies on cerebral glutamine excretion in schizophrenics under treatment with tranquilizing agents].
    Psychiatria clinica, 1973, Volume: 6, Issue:5

    Topics: Acute Disease; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Ammonia; Antipsychotic Agents; Brain; Convalescence; Female; Glutamine; Humans; Hydrolysis; Male; Phenothiazines; Remission, Spontaneous; Schizophrenia; Tranquilizing Agents

1973
[Relationship between the effect of phenothiazine and butyrophenone and the glutamine level in the blood of schizophrenics].
    Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1968, Volume: 26, Issue:2

    Topics: Brain Neoplasms; Butyrophenones; Epilepsy; Glutamine; Humans; Phenothiazines; Schizophrenia

1968
Cerebral metabolism in schizophrenia. Study on L-(U- 14 C) glutamine and L-(U- 14 C) glutamic acid under basal conditions and in hypoglycemic coma.
    Activitas nervosa superior, 1972, Volume: 14, Issue:1

    Topics: Adult; Biological Transport, Active; Blood Gas Analysis; Blood-Brain Barrier; Brain; Carbon Dioxide; Carbon Isotopes; Cerebrovascular Circulation; Coma; Glutamates; Glutamine; Humans; Hypoglycemia; Male; Schizophrenia

1972