glutamine and Pain

glutamine has been researched along with Pain in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.00)18.7374
1990's2 (6.67)18.2507
2000's10 (33.33)29.6817
2010's7 (23.33)24.3611
2020's8 (26.67)2.80

Authors

AuthorsStudies
Alkindi, S; Estepp, J; Ezzat, H; Lam, H; Minniti, CP; Shah, N; Zaidi, AU1
Fasipe, TA; Kavanagh, PL; Wun, T1
Adel, AM; Al-Okka, R; Elenga, N; Etienne-Julan, M; Loko, G; Yassin, MA1
Burns, BN; Cieri-Hutcherson, NE; Conway-Habes, EE; Hutcherson, TC; White, NA1
Archibald, J; Enzler, A; Jutzeler, CR; Kramer, JLK; MacMillan, EL; Schweinhardt, P1
Gordeuk, VR; Han, J; Saraf, SL1
Ashley-Koch, AE; Bartolucci, P; Brugnara, C; Clish, CB; Galactéros, F; Garrett, ME; Hirschhorn, JN; Ilboudo, Y; Lettre, G; Telen, MJ1
Archibald, J; Graf, C; Kozlowski, P; Kramer, JLK; Laule, C; MacMillan, EL1
Al-Taie, A; Koseoglu, A1
Bellevue, R; Blake, OA; Gordeuk, VR; Guillaume, E; Hsu, LL; Kanter, J; Lanzkron, S; Lasky, JL; Miller, ST; Neumayr, LD; New, TN; Niihara, Y; Osunkwo, I; Panosyan, EH; Razon, RL; Sadanandan, S; Sarnaik, S; Sieger, L; Smith, WR; Stark, CW; Tran, LT; Vichinsky, EP; Viswanathan, K1
Andrés, E; Fayed, N; Garcia-Campayo, J; Modrego, PJ; Viguera, L1
Bingel, U; Harris, RE; Schmidt-Wilcke, T; Schweizer, LM; Witte, V; Zunhammer, M1
Chiang, CY; Dostrovsky, JO; Hu, JW; Li, Z; Sessle, BJ1
Liu, JH; Tu, XH; Wang, L; Wang, Y; Zhang, ZZ; Zou, ZD1
Clauw, DJ; Craig, AD; Harris, RE; Kirshenbaum, E; Napadow, V; Sen, A; Sundgren, PC1
Baccei, ML1
Andres, E; Andrés-Bergareche, H; Beltrán, J; Fayed, N; Garcia-Campayo, J; Luciano, JV; Magallón, R1
Binkert, CA; Brügger, M; Ettlin, DA; Froehlich, JM; Graf, N; Gutzeit, A; Meier, D; Meier, ML; von Weymarn, C1
Fujita, T; Kawasaki, Y; Kumamoto, E; Lao, LJ; Yang, K1
Jung, RE; Mullins, PG; Rowland, LM; Sibbitt, WL1
Premkumar, LS; Sikand, P1
Chiang, CY; Dostrovsky, JO; Hu, JW; Sessle, BJ; Wang, J; Xie, YF; Zhang, S1
D'Mello, R; Dickenson, AH1
Boucher, J; Corey, B; Savarese, D1
Giovengo, SL; Larson, AA; Michalek, JE; Russell, JI1
Hasegawa, K; Hiramatsu, Y; Hongo, A; Kodama, J; Kudo, T; Kuramoto, H; Masuyama, H; Mizutani, Y; Nagao, S; Okuda, H; Yoshinouchi, M1
Urca, G; Urca, R1
Godhwani, JL; Jain, P; Khanna, NK1
Kinscheck, IB; Mayer, DJ; Watkins, LR1
Miller, J; Price, C; Price, DD; Rafii, A; von der Gruen, A1

Reviews

5 review(s) available for glutamine and Pain

ArticleYear
Sickle Cell Disease: A Review.
    JAMA, 2022, 07-05, Volume: 328, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Antibodies, Monoclonal, Humanized; Antisickling Agents; Benzaldehydes; Child; Glutamine; Hematologic Agents; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Infant, Newborn; Neonatal Screening; Pain; Pyrazines; Pyrazoles; Transition to Adult Care; United States

2022
Systematic Review of l-glutamine for Prevention of Vaso-occlusive Pain Crisis in Patients with Sickle Cell Disease.
    Pharmacotherapy, 2019, Volume: 39, Issue:11

    Topics: Anemia, Sickle Cell; Glutamine; Hospitalization; Humans; Pain; Randomized Controlled Trials as Topic

2019
Excitatory and inhibitory responses in the brain to experimental pain: A systematic review of MR spectroscopy studies.
    NeuroImage, 2020, 07-15, Volume: 215

    Topics: Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Pain; Pain Threshold

2020
Systematic Review of Crizanlizumab: A New Parenteral Option to Reduce Vaso-occlusive Pain Crises in Patients with Sickle Cell Disease.
    Pharmacotherapy, 2020, Volume: 40, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Antibodies, Monoclonal, Humanized; Glutamine; Humans; Hydroxyurea; P-Selectin; Pain; Randomized Controlled Trials as Topic

2020
Spinal cord mechanisms of pain.
    British journal of anaesthesia, 2008, Volume: 101, Issue:1

    Topics: Analgesics; Animals; Brain Stem; Glutamine; Humans; Neural Pathways; Nociceptors; Pain; Pain Management; Posterior Horn Cells; Spinal Cord

2008

Trials

4 trial(s) available for glutamine and Pain

ArticleYear
Potential therapeutic effects of different mouthwashes for alleviation and treatment of oral complications of 5-fluorouracil-based chemotherapy in patients with colon cancer.
    European journal of hospital pharmacy : science and practice, 2023, Volume: 30, Issue:4

    Topics: Benzydamine; Colonic Neoplasms; Fluorouracil; Glutamine; Humans; Mouthwashes; Pain; Prospective Studies; Quality of Life; Sodium Bicarbonate; Stomatitis; Xerostomia

2023
A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
    The New England journal of medicine, 2018, Jul-19, Volume: 379, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; beta-Thalassemia; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Glutamine; Humans; Hydroxyurea; Intention to Treat Analysis; Male; Middle Aged; Pain; Pain Management; Young Adult

2018
Safety and efficacy of Qingre Buyi Decoction in the treatment of acute radiation proctitis: a prospective, randomized and controlled trial.
    Chinese journal of integrative medicine, 2009, Volume: 15, Issue:4

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Azulenes; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Gastrointestinal Agents; Glutamine; Humans; Integrative Medicine; Male; Middle Aged; Norfloxacin; Pain; Proctitis; Sesquiterpenes; Silicates; Single-Blind Method; Treatment Outcome

2009
A novel technique to study the brain's response to pain: proton magnetic resonance spectroscopy.
    NeuroImage, 2005, Volume: 26, Issue:2

    Topics: Adult; Brain; Brain Chemistry; Cold Temperature; Female; Glutamic Acid; Glutamine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Pain; Pain Measurement; Pressure; Protons; Synaptic Transmission

2005

Other Studies

21 other study(ies) available for glutamine and Pain

ArticleYear
A reanalysis of pain crises data from the pivotal l-glutamine in sickle cell disease trial.
    Contemporary clinical trials, 2021, Volume: 110

    Topics: Anemia, Sickle Cell; Communication; Glutamine; Humans; Pain

2021
"Long-term efficacy and safety of L-glutamine in preventing sickle cell disease-related acute complications and hemolysis in pediatric and adult patients-Real-world, observational study".
    European journal of haematology, 2023, Volume: 110, Issue:6

    Topics: Adult; Anemia, Sickle Cell; Child; Glutamine; Hemolysis; Humans; Pain

2023
Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis.
    Blood cells, molecules & diseases, 2021, Volume: 86

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Female; Glutamine; Humans; Male; Mendelian Randomization Analysis; Middle Aged; Pain; Young Adult

2021
Metabolite activity in the anterior cingulate cortex during a painful stimulus using functional MRS.
    Scientific reports, 2020, 11-05, Volume: 10, Issue:1

    Topics: Adult; Female; Functional Neuroimaging; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pain; Young Adult

2020
Higher glutamate+glutamine and reduction of N-acetylaspartate in posterior cingulate according to age range in patients with cognitive impairment and/or pain.
    Academic radiology, 2014, Volume: 21, Issue:9

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cognition Disorders; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pain; Prospective Studies

2014
Combined glutamate and glutamine levels in pain-processing brain regions are associated with individual pain sensitivity.
    Pain, 2016, Volume: 157, Issue:10

    Topics: Adult; Brain; Brain Mapping; Cross-Sectional Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Hyperalgesia; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Pain; Pain Threshold; Protons; Young Adult

2016
Glutamine uptake contributes to central sensitization in the medullary dorsal horn.
    Neuroreport, 2008, Jul-16, Volume: 19, Issue:11

    Topics: Amino Acid Transport System A; Animals; beta-Alanine; Dental Pulp; Drug Interactions; Glutamine; Male; Medulla Oblongata; Mustard Plant; Nociceptors; Pain; Pain Threshold; Plant Oils; Posterior Horn Cells; Rats; Stimulation, Chemical; Time Factors; Trigeminal Caudal Nucleus

2008
Elevated insular glutamate in fibromyalgia is associated with experimental pain.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:10

    Topics: Adult; Case-Control Studies; Cerebral Cortex; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Pain; Pain Threshold

2009
Modulation of developing dorsal horn synapses by tissue injury.
    Annals of the New York Academy of Sciences, 2010, Volume: 1198

    Topics: Animals; Animals, Newborn; Bradykinin; Carrageenan; Child; Edema; Evoked Potentials; Functional Laterality; Glutamine; Hindlimb; Humans; Infant; Infant, Newborn; Inflammation; Pain; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Serotonin; Skin; Synapses; Synaptic Transmission

2010
Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate.
    Arthritis research & therapy, 2010, Volume: 12, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Cholic Acid; Cross-Sectional Studies; Diffusion Tensor Imaging; Female; Fibromyalgia; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Male; Middle Aged; Motor Cortex; Nuclear Magnetic Resonance, Biomolecular; Pain; Protons; Somatosensory Cortex

2010
Insula-specific responses induced by dental pain. A proton magnetic resonance spectroscopy study.
    European radiology, 2011, Volume: 21, Issue:4

    Topics: Adult; Aspartic Acid; Cerebral Cortex; Electrodes; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Models, Anatomic; Neurotransmitter Agents; Pain; Prospective Studies; Protons; Tooth Diseases; Trigeminal Nerve

2011
Modulation by adenosine of Adelta and C primary-afferent glutamatergic transmission in adult rat substantia gelatinosa neurons.
    Neuroscience, 2004, Volume: 125, Issue:1

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Glutamine; Male; Neurons, Afferent; Organ Culture Techniques; Pain; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Synaptic Transmission

2004
Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse.
    The Journal of physiology, 2007, Jun-01, Volume: 581, Issue:Pt 2

    Topics: Animals; Bradykinin; Calcium; Capsaicin; Cells, Cultured; Coculture Techniques; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Ganglia, Spinal; Glutamine; Indoles; Maleimides; Neuronal Plasticity; Neurons, Afferent; Pain; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphorylation; Posterior Horn Cells; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Sprague-Dawley; Synaptic Transmission; TRPV Cation Channels; Type C Phospholipases

2007
Astroglial glutamate-glutamine shuttle is involved in central sensitization of nociceptive neurons in rat medullary dorsal horn.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Aug-22, Volume: 27, Issue:34

    Topics: Action Potentials; Analysis of Variance; Animals; Dental Pulp; Drug Interactions; Glutamine; Isothiocyanates; Male; Methionine Sulfoximine; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trigeminal Caudal Nucleus

2007
Glutamine treatment of paclitaxel-induced myalgias and arthralgias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Arthralgia; Female; Glutamine; Humans; Male; Middle Aged; Muscles; Neoplasms; Paclitaxel; Pain

1998
Changes in the concentrations of amino acids in the cerebrospinal fluid that correlate with pain in patients with fibromyalgia: implications for nitric oxide pathways.
    Pain, 2000, Volume: 87, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Asparagine; Excitatory Amino Acids; Female; Fibromyalgia; Glutamine; Humans; Male; Middle Aged; N-Methylaspartate; Nitric Oxide; Pain; Pain Measurement; Signal Transduction

2000
[The effect of L-Glutamine and Shakuyaku-Kanzo-to for paclitaxel-induced myalgia/arthralgia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Arthralgia; Drug Administration Schedule; Drug Combinations; Drugs, Chinese Herbal; Female; Glutamine; Glycyrrhiza; Humans; Muscle, Skeletal; Neoplasms; Paclitaxel; Paeonia; Pain; Quality of Life

2002
Neurotoxic effects of excitatory amino acids in the mouse spinal cord: quisqualate and kainate but not N-methyl-D-aspartate induce permanent neural damage.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Aggression; Animals; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methylaspartate; Neurons; Neurotoxins; Pain; Paralysis; Quisqualic Acid; Spinal Cord

1990
A possible drug interaction between aspirin and L-glutamine on some experimental inflammatory and analgesic models.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Drug Interactions; Female; Glutamine; Inflammation; Male; Mice; Mice, Inbred Strains; Pain; Rats

1988
Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide.
    Brain research, 1985, Feb-18, Volume: 327, Issue:1-2

    Topics: Analgesia; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Drug Synergism; Glutamine; Injections, Spinal; Male; Microinjections; Morphine; Pain; Periaqueductal Gray; Proglumide; Rats; Rats, Inbred Strains; Reaction Time; Time Factors

1985
Potentiation of systemic morphine analgesia in humans by proglumide, a cholecystokinin antagonist.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:8

    Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Glutamine; Humans; Injections, Intravenous; Morphine; Pain; Proglumide; Random Allocation

1985