glutamine and Neoplasm Metastasis

glutamine has been researched along with Neoplasm Metastasis in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's2 (6.90)18.2507
2000's2 (6.90)29.6817
2010's19 (65.52)24.3611
2020's5 (17.24)2.80

Authors

AuthorsStudies
Hua, Q; Lin, Z; Ren, J; Wang, H; Wang, L; Xu, G; Yu, D; Zhang, B; Zhang, D; Zhang, T; Zhao, L1
Bagchi, A; Commisso, C; Galenkamp, KMO; James, B; Jung, M; Lowy, A; Moldenhauer, MR; Recouvreux, MV; Zhang, Y1
Guan, R; Huang, J; Jian, Z; Jin, H; Lin, Y; Wei, X; Wu, X; Zou, X1
Barry, ST; Brown, G; Bunch, J; Bushell, M; Campbell, AD; Ceteci, F; Clark, W; Critchlow, SE; Dexter, A; Dunne, PD; Fey, SK; Gay, DM; Gilroy, K; Goodwin, RJA; Gottlieb, E; Hall, H; Hamm, G; Hedley, A; Jackstadt, R; Johnson, ER; Knight, JRP; Leach, JDG; Lewis, DY; Mackay, GM; Malla, SB; Malviya, G; Mrowinska, A; Murta, T; Najumudeen, AK; Nikula, CJ; Nixon, C; Race, AM; Ridgway, RA; Rodriguez-Blanco, G; Sansom, OJ; Solovyev, D; Steven, RT; Strathdee, D; Sumpton, D; Takats, Z; Tardito, S; Vlahov, N1
Bergers, G; Fendt, SM1
Agostinis, P; Maes, H; Van Dingenen, S; Vara-Perez, M1
Dorai, T; Hsieh, TC; Huang, J; Mathew, R; Shah, A; Summers, F; Wu, JM1
Mathews, EH; Mathews, GE; Meyer, AA1
Bettigole, SE; Cerliani, JP; Chae, CS; Chaurio, RA; Chopra, S; Conejo-Garcia, JR; Crowley, MJP; Cubillos-Ruiz, JR; Glimcher, LH; Holcomb, K; Konrad, C; Kossenkov, AV; Manfredi, G; Motorykin, I; Payne, KK; Rabinovich, GA; Raundhal, M; Rodriguez, PC; Rutkowski, MR; Sandoval, TA; Shin, HR; Song, M; Tan, C; Zamarin, D; Zhang, S1
Chen, Z; Li, Z; Sun, G; Wang, S; Wang, W; Xu, J; Xu, P; Xu, Z; Xuan, Z; Zhang, X1
Adriaensens, P; Derveaux, E; Graulus, GJ; Guedens, W; Mesotten, L; Noben, JP; Thomeer, M; Vanhove, K1
Fingleton, B; Williams, D1
Hatziapostolou, M; Iliopoulos, D; Polytarchou, C1
Foygel, K; Ilovich, O; Paulmurugan, R; Sekar, TV1
Han, S; Kim, C; Kim, HC; Kim, KE; Kim, S; Kim, YI; Ko, E; Lee, HS; Lee, KH; Lee, YS; Oh, SJ; Song, PH1
Antonyak, MA; Cerione, RA; Katt, WP1
Bailey, CG; Balaban, S; Fazli, L; Gao, D; Gleave, M; Hardie, RA; Holst, J; Hoy, AJ; Lehman, ML; Metierre, C; Nagarajah, R; Nelson, CC; Otte, NJ; Pinello, N; Rasko, JE; Ritchie, W; Sadowski, MC; Schreuder, M; van Geldermalsen, M; Wang, Q; Wong, JJ1
Cai, C; Chen, R; Fu, Z; Gong, Y; Han, F; Li, Y; Li, Z; Lin, Q; Liu, G; Tang, C; Yang, B; Ye, H; Ye, L; Yu, M; Zeng, B; Zhao, X; Zhou, Q; Zhou, Y; Zhu, J1
Ackerstaff, E; Blasberg, RG; Koutcher, JA; Kruchevsky, N; Leftin, A; Locasale, JW; Serganova, IS; Shestov, AA; Simões, RV; Sukenick, G; Thaler, HT1
Asai, A; Colvin, H; Doki, Y; Haraguchi, N; Hata, T; Ishii, H; Kawamoto, K; Konno, M; Koseki, J; Mizushima, T; Mori, M; Nishida, N; Nishimura, J; Satoh, T; Takahashi, H; Tsunekuni, K1
Achreja, A; Baddour, J; Choi, HH; Han, C; Huang, C; Ji, G; Li, J; Li, Y; Liu, Y; Lu, X; Nagrath, D; Wan, G; Yang, L; Zhang, X1
Huysentruyt, LC; Seyfried, TN; Shelton, LM1
Dafni, H; Ronen, SM1
Bajaj, A; Braunlin, M; Cady, AM; Irving, LR; Lucci, A; Madan, S; Raythatha, MR; Singh, B; Tai, K1
Basilico, C; Cavassa, S; Comoglio, PM; Mazzone, M; Michieli, P; Naldini, L; Pennacchietti, S; Risio, M1
Asensi, M; Benlloch, M; Brown, BD; Carretero, J; Estrela, JM; Mena, S; Obrador, E; Ortega, A; Petschen, I1
Boschek, CB; Eigenbrodt, E; Mazurek, S1
Board, M; Humm, S; Newsholme, EA1
Laki, K; Yancey, ST1

Reviews

6 review(s) available for glutamine and Neoplasm Metastasis

ArticleYear
The metabolism of cancer cells during metastasis.
    Nature reviews. Cancer, 2021, Volume: 21, Issue:3

    Topics: Acetates; Adenosine Triphosphate; Animals; Cell Plasticity; Fatty Acids; Glutamine; Humans; Lactic Acid; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; Pyruvic Acid

2021
Glutamine Addiction and Therapeutic Strategies in Lung Cancer.
    International journal of molecular sciences, 2019, Jan-10, Volume: 20, Issue:2

    Topics: Animals; Biological Transport; Glutamine; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Molecular Targeted Therapy; Neoplasm Metastasis; Signal Transduction

2019
Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis.
    Clinical & experimental metastasis, 2019, Volume: 36, Issue:3

    Topics: ATP Citrate (pro-S)-Lyase; Disease Progression; Energy Metabolism; Fatty Acids; Glucose; Glucose-6-Phosphate Isomerase; Glutaminase; Glutamine; Humans; Isocitrate Dehydrogenase; Neoplasm Metastasis; Neoplasms

2019
miRNAs link metabolic reprogramming to oncogenesis.
    Trends in endocrinology and metabolism: TEM, 2013, Volume: 24, Issue:7

    Topics: Animals; Carcinogenesis; Cell Proliferation; Citric Acid Cycle; Energy Metabolism; Glutamine; Glycolysis; Humans; Lipogenesis; MicroRNAs; Neoplasm Metastasis; Neoplasms; Signal Transduction

2013
Dynamic nuclear polarization in metabolic imaging of metastasis: common sense, hypersense and compressed sensing.
    Cancer biomarkers : section A of Disease markers, 2010, Volume: 7, Issue:4

    Topics: Bicarbonates; Diagnostic Imaging; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neoplasm Metastasis; Neoplasms; Pyruvic Acid

2010
The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy.
    Journal of bioenergetics and biomembranes, 1997, Volume: 29, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Energy Metabolism; Glutamine; Glycolysis; Humans; Neoplasm Metastasis; Neoplasms; Phosphates

1997

Other Studies

23 other study(ies) available for glutamine and Neoplasm Metastasis

ArticleYear
CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin.
    Oncogene, 2021, Volume: 40, Issue:46

    Topics: Amino Acid Transport System A; Amino Acid Transport System ASC; Animals; beta Catenin; Cell Line, Tumor; Cell Nucleus; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glutamine; HCT116 Cells; Humans; Hyaluronoglucosaminidase; Mice; Minor Histocompatibility Antigens; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Neoplasm Transplantation; Transcription, Genetic

2021
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer.
    The Journal of experimental medicine, 2020, 09-07, Volume: 217, Issue:9

    Topics: Activating Transcription Factor 4; Adenocarcinoma; Animals; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Glutamine; HEK293 Cells; Humans; MAP Kinase Signaling System; Mice, Inbred C57BL; Neoplasm Metastasis; Pancreatic Neoplasms; RNA, Messenger; Snail Family Transcription Factors; Stress, Physiological

2020
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
    Aging, 2020, 07-27, Volume: 12, Issue:14

    Topics: Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Discoidin Domain Receptor 1; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutamine; Humans; Liver Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Prognosis; Receptor Cross-Talk; STAT3 Transcription Factor

2020
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
    Nature genetics, 2021, Volume: 53, Issue:1

    Topics: 5' Untranslated Regions; Amino Acid Transport System ASC; Animals; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Intestinal Mucosa; Kaplan-Meier Estimate; Large Neutral Amino Acid-Transporter 1; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Mutation; Neoplasm Metastasis; Oncogenes; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases

2021
BNIP3 contributes to the glutamine-driven aggressive behavior of melanoma cells.
    Biological chemistry, 2019, 01-28, Volume: 400, Issue:2

    Topics: Cell Line, Tumor; Cell Proliferation; Energy Metabolism; Gene Silencing; Glutamine; Humans; Melanoma; Membrane Proteins; Neoplasm Metastasis; Proto-Oncogene Proteins; Skin Neoplasms

2019
NRH:quinone oxidoreductase 2 (NQO2) and glutaminase (GLS) both play a role in large extracellular vesicles (LEV) formation in preclinical LNCaP-C4-2B prostate cancer model of progressive metastasis.
    The Prostate, 2018, Volume: 78, Issue:15

    Topics: Amino Acid Sequence; Binding Sites; Caveolin 1; Cell Line, Tumor; Disease Progression; Extracellular Vesicles; Glutaminase; Glutamine; Humans; Immunoblotting; Male; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Neoplasm Metastasis; Oxidative Stress; Prostatic Neoplasms; Quinone Reductases

2018
A hypothetical method for controlling highly glycolytic cancers and metastases.
    Medical hypotheses, 2018, Volume: 118

    Topics: Blood Glucose; Cell Proliferation; Cerebrovascular Circulation; Deoxyglucose; Diet, Ketogenic; Glutamine; Glycolysis; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Models, Theoretical; Neoplasm Metastasis; Neoplasms

2018
IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.
    Nature, 2018, Volume: 562, Issue:7727

    Topics: Amino Acid Transport Systems, Basic; Animals; Ascites; Cell Respiration; Disease Progression; Endoplasmic Reticulum Stress; Endoribonucleases; Female; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycosylation; Humans; Interferon-gamma; Mice; Mitochondria; Neoplasm Metastasis; Neoplasm Transplantation; Ovarian Neoplasms; Protein Serine-Threonine Kinases; Signal Transduction; Survival Rate; T-Lymphocytes; Tumor Escape; Unfolded Protein Response; X-Box Binding Protein 1

2018
Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis.
    Journal of experimental & clinical cancer research : CR, 2018, Dec-20, Volume: 37, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Autophagy; Cell Line, Tumor; Down-Regulation; Female; Glutamine; Heterografts; Humans; Male; Mice; Mice, Nude; MicroRNAs; Microtubule-Associated Proteins; Middle Aged; Neoplasm Metastasis; Stomach Neoplasms; Transfection

2018
Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice.
    Theranostics, 2014, Volume: 4, Issue:5

    Topics: Animals; Antineoplastic Agents; Aziridines; Disease Models, Animal; Genetic Therapy; Glutamine; Lung Neoplasms; Mice; Neoplasm Metastasis; Nitroreductases; Optical Imaging; Organometallic Compounds; Prodrugs; Radiography; Thymidine Kinase; Treatment Outcome; Triple Negative Breast Neoplasms

2014
Gln-362 of angiopoietin-2 mediates migration of tumor and endothelial cells through association with α5β1 integrin.
    The Journal of biological chemistry, 2014, Nov-07, Volume: 289, Issue:45

    Topics: Angiopoietin-2; Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Endothelial Cells; Gene Expression Regulation; Glutamine; Humans; Integrin alpha5beta1; Integrins; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Plasmids; Protein Structure, Tertiary; Receptor, TIE-2

2014
Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention.
    Molecular pharmaceutics, 2015, Jan-05, Volume: 12, Issue:1

    Topics: Allosteric Site; Ammonia; Antineoplastic Agents; Catalysis; Catalytic Domain; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Glutamic Acid; Glutamine; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kidney; Neoplasm Metastasis; Neoplasms; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases

2015
Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.
    The Journal of pathology, 2015, Volume: 236, Issue:3

    Topics: Amino Acid Transport System ASC; Animals; Biological Transport; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Fatty Acids; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutamine; Heterografts; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Nude; Minor Histocompatibility Antigens; Multiprotein Complexes; Neoplasm Metastasis; Oxygen; Prostatic Neoplasms; RNA, Small Interfering; TOR Serine-Threonine Kinases

2015
Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients.
    Journal of translational medicine, 2015, May-07, Volume: 13

    Topics: Aged; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Glutamate Dehydrogenase; Glutamine; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Proportional Hazards Models; Up-Regulation

2015
Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.
    Neoplasia (New York, N.Y.), 2015, Volume: 17, Issue:8

    Topics: Adaptation, Physiological; Animals; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hydrogen-Ion Concentration; Mammary Neoplasms, Animal; Mice, Inbred BALB C; Neoplasm Metastasis; Oxidative Phosphorylation; Phospholipids; Tumor Microenvironment

2015
Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer.
    Scientific reports, 2016, 11-08, Volume: 6

    Topics: Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Glutamine; Glutarates; HCT116 Cells; HEK293 Cells; Histones; HT29 Cells; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasm Metastasis; Promoter Regions, Genetic; Zinc Finger E-box-Binding Homeobox 1

2016
Amplification of USP13 drives ovarian cancer metabolism.
    Nature communications, 2016, 11-28, Volume: 7

    Topics: Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Endopeptidases; Female; Gene Amplification; Gene Knockdown Techniques; Genome, Human; Glutamine; HEK293 Cells; Humans; Lipids; Mitochondria; Neoplasm Metastasis; Ovarian Neoplasms; Protein Kinase Inhibitors; Protein Stability; Proto-Oncogene Proteins c-akt; Substrate Specificity; Ubiquitin-Specific Proteases; Ubiquitination

2016
Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model.
    International journal of cancer, 2010, Nov-15, Volume: 127, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Blood Glucose; Body Weight; Brain Neoplasms; Caloric Restriction; Cell Growth Processes; Cell Line, Tumor; Cerebrum; Diazooxonorleucine; Drug Delivery Systems; Female; Glucose; Glutamine; Male; Mice; Neoplasm Metastasis

2010
Selection of metastatic breast cancer cells based on adaptability of their metabolic state.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Adaptation, Biological; Animals; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression; Glutamine; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Proto-Oncogene Proteins c-myc; Vimentin

2012
An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice.
    The Journal of clinical investigation, 2004, Volume: 114, Issue:10

    Topics: Amino Acid Substitution; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Collagen; Enzyme Activation; Extracellular Matrix; Female; Genetic Therapy; Genetic Vectors; Glutamine; Hepatocyte Growth Factor; Humans; Lentivirus; Methionine; Mice; Mice, Nude; Mitosis; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Protein Engineering; Protein-Tyrosine Kinases; Recombinant Proteins; Transduction, Genetic; Transplantation, Heterologous; Tumor Burden

2004
Bcl-2 and glutathione depletion sensitizes B16 melanoma to combination therapy and eliminates metastatic disease.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-01, Volume: 13, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Glutamine; Glutathione; Melanoma, Experimental; Mice; Neoplasm Metastasis; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Thionucleotides; Treatment Outcome; Tumor Necrosis Factor-alpha; X-Rays

2007
Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells.
    The Biochemical journal, 1990, Jan-15, Volume: 265, Issue:2

    Topics: Cell Line; Citric Acid Cycle; Glutamine; Glycolysis; Humans; Lymphocytes; Macrophages; Neoplasm Metastasis; Pentose Phosphate Pathway; Reference Values; Tumor Cells, Cultured

1990
Transglutaminase and tumor growth.
    Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202

    Topics: Animals; Blood Coagulation; Cross Reactions; Dipeptides; Glutamine; Glycine; Glycosides; Guinea Pigs; Immunization; Immunodiffusion; Liver; Lysine; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Peptides; Plasmacytoma; Putrescine; Rabbits; Transferases

1972