glutamine and Leukemia

glutamine has been researched along with Leukemia in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199019 (50.00)18.7374
1990's4 (10.53)18.2507
2000's3 (7.89)29.6817
2010's10 (26.32)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Manonmani, HK; Sindhu, R1
Ada, S; Yücel, B1
Adane, B; D'Alessandro, A; DeGregori, J; Gehrke, S; Gregory, MA; Hansen, KC; Jordan, CT; Nemkov, T; Park, HJ; Zaberezhnyy, V1
Avramis, VI; Behan, JW; Butturini, A; Ehsanipour, EA; Mittelman, SD; Sheng, X; Wang, X1
Cipolleschi, MG; D'Amico, M; Dello Sbarba, P; Fredducci, D; Marzi, I; Olivotto, M; Rovida, E; Santini, R; Stecca, B; Stivarou, T; Torre, E; Vinci, MC1
Allende-Vega, N; Haouas, H; Hipskind, RA; Krzywinska, E; Lopez-Royuela, N; Rathore, MG; Villalba, M1
Inokuchi, N; Itagaki, T; Kobayashi, H; Motoyoshi, N; Suzuki, M1
Bhuiyan, H; Broom, OJ; Islam, S; Lehtiö, J; Lindahl, A; Linnarsson, S; Nordström, A; Stäubert, C; Zhu, Y1
Bol, V; Corbet, C; Drozak, X; Feron, O; Grégoire, V; Martherus, R; Pinto, A; Polet, F; Riant, O; Rubio, LI1
Corbet, C; Feron, O; Martherus, R; Pinto, A; Polet, F1
Egusa, S; Otani, H1
Avramis, VI1
Adkins, JN; Bordbar, A; Frank, BC; Hyduke, DR; Jones, MB; Kim, YM; Metz, TO; Mo, ML; Nakayasu, ES; Palsson, BO; Peterson, SN; Schrimpe-Rutledge, AC; Smith, RD1
Albertioni, F; Assaraf, YG; Fotoohi, K; Gregorczyk, J; Jansen, G; Kathmann, I; Peters, GJ; Rothem, L; Stark, M1
Cetin, M; Cetin, N; Kucukbayrak, O; Kuskonmaz, B; Tezcan, I; Uckan, D; Yalcin, S1
Harmon, JM; Thompson, EB1
Berezov, TT1
Bendich, A; Kafkewitz, D1
Ohtsuka, C; Takahashi, H1
Brown, OE; Fyfe, MJ; Laszlo, J; Sedwick, WD1
Andersson, LC; Raivio, KO1
Holcenberg, JS1
Alfieri, R; Borghetti, AF; Guidotti, GG; Petronini, PG; Urbani, S1
Sugimura, K; Sukemori, S1
Cooney, DA; Milman, HA; Muth, R1
Bondeson, K; McCabe, M1
Schlaeger, EJ; Schumpp, B1
Chorváth, B; Forgács, A; Horáková, K; Perényi, T; Valentová, N1
Kotlarek-Haus, S1
Carter, SK; Cooney, DA; Livingston, RB; Venditti, JM1
Chakraborty, P; Chowdhuri, MD; Shrivastava, GC1
Beutler, E; Blume, KG; Paniker, NV1
Bachynsky, N; Prager, MD1
van Os, FH1
Canellos, GP; Haskell, CM1
Gerron, GG; Howard, CH; Rudman, D; Vogler, WR1
Holland, JF; Onuma, T; Waligunda, J1
Balis, ME; Krakoff, IH; Miller, HK; Salser, JS1

Reviews

6 review(s) available for glutamine and Leukemia

ArticleYear
L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:13

    Topics: Asparaginase; Asparagine; Child; Escherichia coli; Glutaminase; Glutamine; Humans; Leukemia

2022
Chemical metabolic inhibitors for the treatment of blood-borne cancers.
    Anti-cancer agents in medicinal chemistry, 2014, Volume: 14, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Transplantation; Combined Modality Therapy; Glutamine; Glycolysis; Histocompatibility Antigens Class I; Histone Deacetylases; Humans; Immunomodulation; Killer Cells, Natural; Leukemia; Oxidative Phosphorylation; Sirtuins; T-Lymphocytes, Cytotoxic

2014
[Asparagine biosynthesis and tumor growth].
    Vestnik Akademii meditsinskikh nauk SSSR, 1982, Issue:3

    Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases

1982
Enzyme-induced asparagine and glutamine depletion and immune system function.
    The American journal of clinical nutrition, 1983, Volume: 37, Issue:6

    Topics: Ammonia; Animals; Asparaginase; Asparagine; Escherichia coli; Glutaminase; Glutamine; Humans; Immunosuppressive Agents; Leukemia; Lymphocytes; Polyethylene Glycols; Vibrio

1983
Glutamine antagonists in chemotherapy.
    Advances in pharmacology and chemotherapy, 1970, Volume: 8

    Topics: Adult; Aminobutyrates; Animals; Asparaginase; Azaserine; Azo Compounds; Child; Diazooxonorleucine; Drug Combinations; Drug Interactions; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Hydroxylysine; Leukemia; Leukemia L1210; Liver; Methionine Sulfoximine; Mice; Neoplasms; Rats; RNA, Transfer

1970
[Plants with cytostatic effect].
    Il Farmaco; edizione scientifica, 1970, Volume: 25, Issue:6

    Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine

1970

Other Studies

32 other study(ies) available for glutamine and Leukemia

ArticleYear
Leukemia Cells Resistant to Glutamine Deprivation Express Glutamine Synthetase Protein
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2022, 02-23, Volume: 39, Issue:1

    Topics: Cell Line, Tumor; Glutamate-Ammonia Ligase; Glutamine; HL-60 Cells; Humans; Leukemia; RNA, Messenger

2022
Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-01, Volume: 25, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Energy Metabolism; Glutamine; Humans; Leukemia; Mice; Mice, Transgenic; Molecular Targeted Therapy; Oxidation-Reduction; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2019
Adipocytes cause leukemia cell resistance to L-asparaginase via release of glutamine.
    Cancer research, 2013, May-15, Volume: 73, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Asparaginase; Glutamine; Humans; Leukemia; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Obesity; Tumor Microenvironment

2013
Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Citric Acid Cycle; Glutamine; Humans; Leukemia; Liver Neoplasms, Experimental; Melanoma; Metabolic Networks and Pathways; Mitosis; NADP; Neoplastic Stem Cells; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar; Tetrahydrofolates

2014
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; Basidiomycota; Cell Proliferation; Glutamic Acid; Glutamine; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Leukemia; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Ribonucleases; Structure-Activity Relationship

2015
Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine.
    The Journal of biological chemistry, 2015, Mar-27, Volume: 290, Issue:13

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbon-Carbon Double Bond Isomerases; Cell Line, Tumor; Cyclosporins; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Enoyl-CoA Hydratase; Fatty Acids; Glutamine; Glycolysis; Humans; Leukemia; Metabolome; Oxidation-Reduction; Pantothenic Acid; Perhexiline; Racemases and Epimerases; RNA, Messenger; Transcriptome

2015
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Electrophoresis, Gel, Two-Dimensional; Glucose; Glutamine; HL-60 Cells; Humans; Immunoblotting; K562 Cells; Kaplan-Meier Estimate; Leukemia; Mice; Phosphoglycerate Dehydrogenase; Proteomics; RNA Interference; Serine; Transaminases

2016
Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells.
    Oncotarget, 2016, Jul-19, Volume: 7, Issue:29

    Topics: Amino Acid Transport System ASC; Cell Line, Tumor; Cell Proliferation; Glucose; Glutamine; Glycosylation; Humans; Large Neutral Amino Acid-Transporter 1; Leukemia; Minor Histocompatibility Antigens; Up-Regulation

2016
Characterization of a cellular immunostimulating peptide from a soybean protein fraction digested with peptidase R.
    Journal of nutritional science and vitaminology, 2009, Volume: 55, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Antigens, CD; Cell Culture Techniques; Cell Line, Tumor; Chromatography; Glutamine; Glycine max; Humans; Interferon-gamma; Interleukin-12; K562 Cells; Leukemia; Mice; Mice, Inbred C3H; Peptide Hydrolases; Peptides; Protein Subunits; Rhizopus; Soybean Proteins; Spleen

2009
Asparaginases: a successful class of drugs against leukemias and lymphomas.
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:8

    Topics: Antineoplastic Agents; Asparaginase; Drug Design; Energy Metabolism; Escherichia coli Proteins; Glutamine; Humans; Leukemia; Lymphoma

2011
Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation.
    Molecular systems biology, 2012, Jun-26, Volume: 8

    Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Glutamine; Immunologic Factors; Leukemia; Macrophage Activation; Metabolic Networks and Pathways; Metabolomics; Mice; Models, Biological; Nitric Oxide; Proteomics; Transcriptome

2012
Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.
    Blood, 2004, Dec-15, Volume: 104, Issue:13

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line, Tumor; Drug Resistance, Neoplasm; Glutamine; Humans; Leukemia; Methotrexate

2004
The effect of glutamine supplementation on hematopoietic stem cell transplant outcome in children: a case-control study.
    Pediatric transplantation, 2008, Volume: 12, Issue:1

    Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dietary Supplements; Female; Glutamine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Postoperative Complications

2008
Glutamine synthetase induction by glucocorticoids in the glucocorticoid-sensitive human leukemic cell line CEM-C7.
    Journal of cellular physiology, 1982, Volume: 110, Issue:2

    Topics: Bromodeoxyuridine; Cell Division; Clone Cells; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Humans; Kinetics; Leukemia; Receptors, Glucocorticoid; Steroids

1982
Brain function estimated from the ratio of glutamine to homocarnosine levels in cerebrospinal fluid.
    Brain & development, 1983, Volume: 5, Issue:5

    Topics: Bacterial Infections; Carnosine; Child; Child, Preschool; Dipeptides; Epilepsy; Female; Glutamine; Humans; Infant; Infant, Newborn; Leukemia; Male; Meningeal Neoplasms; Meningitis; Meningitis, Viral; Seizures, Febrile

1983
Human plasma and amino acids as moderators of uptake and metabolic consequences of antifolates in WIL-2 and human leukemia cells.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:3

    Topics: Amino Acids; Blood; Cell Line; Culture Media; Deoxyuridine; Folic Acid Antagonists; Glutamine; Humans; Kinetics; Leukemia; Lymphocytes; Methotrexate; Pyrimethamine

1981
Glutamine requirements for purine metabolism in leukemic lymphoblasts.
    Leukemia research, 1982, Volume: 6, Issue:1

    Topics: B-Lymphocytes; Cell Line; Glutamine; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Lymphocytes; Lymphocytes, Null; Purines; T-Lymphocytes

1982
Enzyme therapy of cancer, future studies.
    Cancer treatment reports, 1981, Volume: 65 Suppl 4

    Topics: Adolescent; Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Asparaginase; Asparagine; Child; Child, Preschool; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Therapy; Enzymes; Female; Glutaminase; Glutamine; Humans; Kinetics; Leukemia; Male; Mice

1981
Cell susceptibility to apoptosis by glutamine deprivation and rescue: survival and apoptotic death in cultured lymphoma-leukemia cell lines.
    Journal of cellular physiology, 1996, Volume: 169, Issue:1

    Topics: Apoptosis; Cell Survival; Culture Media; Energy Metabolism; Glucose; Glutamine; Humans; Leukemia; Lymphoma; Signal Transduction; Tumor Cells, Cultured

1996
Extracellular glutamine level reduction enhances 5-fluorouracil cytotoxicity.
    Cancer biochemistry biophysics, 1998, Volume: 16, Issue:1-2

    Topics: Amino Acids; Animals; Asparagine; Cell Count; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Humans; Leukemia; Leukemia P388; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1998
Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase.
    Enzyme, 1979, Volume: 24, Issue:1

    Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Aspartate-Ammonia Ligase; Aspartic Acid; Cells, Cultured; Diphosphates; Glutamine; Kidney; Leukemia; Ligases; Liver; Malonates; Mice; Pancreas; Proteins

1979
Apparent heterogeneity between leukemic lymphocyte cell lines.
    Advances in experimental medicine and biology, 1992, Volume: 316

    Topics: Biological Transport, Active; Glutamine; Glycolysis; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia; Lymphocytes; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oxygen Consumption; Polarography; Tumor Cells, Cultured

1992
Growth study of lactate and ammonia double-resistant clones of HL-60 cells.
    Cytotechnology, 1992, Volume: 8, Issue:1

    Topics: Ammonium Chloride; Cell Division; Clone Cells; Drug Resistance; Glucose; Glutamine; Humans; Kinetics; Lactates; Lactic Acid; Leukemia; Tumor Cells, Cultured

1992
Study of metabolism and growth limitation of human leukemia cell lines.
    Neoplasma, 1989, Volume: 36, Issue:3

    Topics: Amino Acids; Ammonia; Cell Count; Cell Division; Cell Line; Culture Media; Glucose; Glutamine; Humans; Keto Acids; Leukemia; Ornithine; Pyruvates; Tumor Cells, Cultured

1989
[Behavior of aminopeptidase activity in human leukemic leukocytes].
    Folia haematologica (Leipzig, Germany : 1928), 1971, Volume: 96, Issue:3

    Topics: Acyltransferases; Adolescent; Adult; Aged; Aminopeptidases; Aspartic Acid; Child; Clinical Enzyme Tests; Eosinophils; Female; Glutamine; Glycine; Histocytochemistry; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Naphthols; Peptide Hydrolases

1971
Ratio of glutamine aminotransferase & glutamine aminohydrolase in plasma of patients with malignant & other blood disorders.
    Indian journal of experimental biology, 1974, Volume: 12, Issue:4

    Topics: Adult; Bone Marrow; Child; Female; Glutaminase; Glutamine; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Transaminases

1974
Enzymes of glutathione synthesis in patients with myeloproliferative disorders.
    Clinica chimica acta; international journal of clinical chemistry, 1973, May-18, Volume: 45, Issue:3

    Topics: Acute Disease; Cysteine; Erythrocytes; Glutamine; Glutathione; Humans; Kinetics; Leukemia; Leukemia, Myeloid; Myeloproliferative Disorders; Peptide Synthases; Polycythemia Vera; Primary Myelofibrosis

1973
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase.
    Archives of biochemistry and biophysics, 1968, Sep-20, Volume: 127, Issue:1

    Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Cell Nucleus; Enzyme Repression; Escherichia coli; Feedback; Glutamine; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Leukemia; Ligases; Liver; Lymphoid Tissue; Lymphoma; Lymphoma, Non-Hodgkin; Lysosomes; Mice; Microsomes; Mitochondria, Liver; Neoplasms, Experimental; Puromycin; Spleen; Stimulation, Chemical

1968
Studies of resistance to L-asparaginase in human leukemia.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Drug Resistance; Escherichia coli; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Ligases

1970
Observations on the plasma amino acids of patients with acute leukemia.
    Cancer research, 1971, Volume: 31, Issue:8

    Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine

1971
Amino acid requirements in vitro of human leukemic cells.
    Cancer research, 1971, Volume: 31, Issue:11

    Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine

1971
Sensitivity to L-asparaginase and amino acid metabolism.
    Journal of the National Cancer Institute, 1970, Volume: 44, Issue:5

    Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium

1970