glutamine has been researched along with Leukemia in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (50.00) | 18.7374 |
| 1990's | 4 (10.53) | 18.2507 |
| 2000's | 3 (7.89) | 29.6817 |
| 2010's | 10 (26.32) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Manonmani, HK; Sindhu, R | 1 |
| Ada, S; Yücel, B | 1 |
| Adane, B; D'Alessandro, A; DeGregori, J; Gehrke, S; Gregory, MA; Hansen, KC; Jordan, CT; Nemkov, T; Park, HJ; Zaberezhnyy, V | 1 |
| Avramis, VI; Behan, JW; Butturini, A; Ehsanipour, EA; Mittelman, SD; Sheng, X; Wang, X | 1 |
| Cipolleschi, MG; D'Amico, M; Dello Sbarba, P; Fredducci, D; Marzi, I; Olivotto, M; Rovida, E; Santini, R; Stecca, B; Stivarou, T; Torre, E; Vinci, MC | 1 |
| Allende-Vega, N; Haouas, H; Hipskind, RA; Krzywinska, E; Lopez-Royuela, N; Rathore, MG; Villalba, M | 1 |
| Inokuchi, N; Itagaki, T; Kobayashi, H; Motoyoshi, N; Suzuki, M | 1 |
| Bhuiyan, H; Broom, OJ; Islam, S; Lehtiö, J; Lindahl, A; Linnarsson, S; Nordström, A; Stäubert, C; Zhu, Y | 1 |
| Bol, V; Corbet, C; Drozak, X; Feron, O; Grégoire, V; Martherus, R; Pinto, A; Polet, F; Riant, O; Rubio, LI | 1 |
| Corbet, C; Feron, O; Martherus, R; Pinto, A; Polet, F | 1 |
| Egusa, S; Otani, H | 1 |
| Avramis, VI | 1 |
| Adkins, JN; Bordbar, A; Frank, BC; Hyduke, DR; Jones, MB; Kim, YM; Metz, TO; Mo, ML; Nakayasu, ES; Palsson, BO; Peterson, SN; Schrimpe-Rutledge, AC; Smith, RD | 1 |
| Albertioni, F; Assaraf, YG; Fotoohi, K; Gregorczyk, J; Jansen, G; Kathmann, I; Peters, GJ; Rothem, L; Stark, M | 1 |
| Cetin, M; Cetin, N; Kucukbayrak, O; Kuskonmaz, B; Tezcan, I; Uckan, D; Yalcin, S | 1 |
| Harmon, JM; Thompson, EB | 1 |
| Berezov, TT | 1 |
| Bendich, A; Kafkewitz, D | 1 |
| Ohtsuka, C; Takahashi, H | 1 |
| Brown, OE; Fyfe, MJ; Laszlo, J; Sedwick, WD | 1 |
| Andersson, LC; Raivio, KO | 1 |
| Holcenberg, JS | 1 |
| Alfieri, R; Borghetti, AF; Guidotti, GG; Petronini, PG; Urbani, S | 1 |
| Sugimura, K; Sukemori, S | 1 |
| Cooney, DA; Milman, HA; Muth, R | 1 |
| Bondeson, K; McCabe, M | 1 |
| Schlaeger, EJ; Schumpp, B | 1 |
| Chorváth, B; Forgács, A; Horáková, K; Perényi, T; Valentová, N | 1 |
| Kotlarek-Haus, S | 1 |
| Carter, SK; Cooney, DA; Livingston, RB; Venditti, JM | 1 |
| Chakraborty, P; Chowdhuri, MD; Shrivastava, GC | 1 |
| Beutler, E; Blume, KG; Paniker, NV | 1 |
| Bachynsky, N; Prager, MD | 1 |
| van Os, FH | 1 |
| Canellos, GP; Haskell, CM | 1 |
| Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
| Balis, ME; Krakoff, IH; Miller, HK; Salser, JS | 1 |
6 review(s) available for glutamine and Leukemia
| Article | Year |
|---|---|
L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review.
Topics: Asparaginase; Asparagine; Child; Escherichia coli; Glutaminase; Glutamine; Humans; Leukemia | 2022 |
Chemical metabolic inhibitors for the treatment of blood-borne cancers.
Topics: Animals; Antineoplastic Agents; Cell Transplantation; Combined Modality Therapy; Glutamine; Glycolysis; Histocompatibility Antigens Class I; Histone Deacetylases; Humans; Immunomodulation; Killer Cells, Natural; Leukemia; Oxidative Phosphorylation; Sirtuins; T-Lymphocytes, Cytotoxic | 2014 |
[Asparagine biosynthesis and tumor growth].
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases | 1982 |
Enzyme-induced asparagine and glutamine depletion and immune system function.
Topics: Ammonia; Animals; Asparaginase; Asparagine; Escherichia coli; Glutaminase; Glutamine; Humans; Immunosuppressive Agents; Leukemia; Lymphocytes; Polyethylene Glycols; Vibrio | 1983 |
Glutamine antagonists in chemotherapy.
Topics: Adult; Aminobutyrates; Animals; Asparaginase; Azaserine; Azo Compounds; Child; Diazooxonorleucine; Drug Combinations; Drug Interactions; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Hydroxylysine; Leukemia; Leukemia L1210; Liver; Methionine Sulfoximine; Mice; Neoplasms; Rats; RNA, Transfer | 1970 |
[Plants with cytostatic effect].
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine | 1970 |
32 other study(ies) available for glutamine and Leukemia
| Article | Year |
|---|---|
Leukemia Cells Resistant to Glutamine Deprivation Express Glutamine Synthetase Protein
Topics: Cell Line, Tumor; Glutamate-Ammonia Ligase; Glutamine; HL-60 Cells; Humans; Leukemia; RNA, Messenger | 2022 |
Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Energy Metabolism; Glutamine; Humans; Leukemia; Mice; Mice, Transgenic; Molecular Targeted Therapy; Oxidation-Reduction; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2019 |
Adipocytes cause leukemia cell resistance to L-asparaginase via release of glutamine.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Asparaginase; Glutamine; Humans; Leukemia; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Obesity; Tumor Microenvironment | 2013 |
Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Citric Acid Cycle; Glutamine; Humans; Leukemia; Liver Neoplasms, Experimental; Melanoma; Metabolic Networks and Pathways; Mitosis; NADP; Neoplastic Stem Cells; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar; Tetrahydrofolates | 2014 |
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; Basidiomycota; Cell Proliferation; Glutamic Acid; Glutamine; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Leukemia; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Ribonucleases; Structure-Activity Relationship | 2015 |
Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbon-Carbon Double Bond Isomerases; Cell Line, Tumor; Cyclosporins; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Enoyl-CoA Hydratase; Fatty Acids; Glutamine; Glycolysis; Humans; Leukemia; Metabolome; Oxidation-Reduction; Pantothenic Acid; Perhexiline; Racemases and Epimerases; RNA, Messenger; Transcriptome | 2015 |
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Electrophoresis, Gel, Two-Dimensional; Glucose; Glutamine; HL-60 Cells; Humans; Immunoblotting; K562 Cells; Kaplan-Meier Estimate; Leukemia; Mice; Phosphoglycerate Dehydrogenase; Proteomics; RNA Interference; Serine; Transaminases | 2016 |
Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells.
Topics: Amino Acid Transport System ASC; Cell Line, Tumor; Cell Proliferation; Glucose; Glutamine; Glycosylation; Humans; Large Neutral Amino Acid-Transporter 1; Leukemia; Minor Histocompatibility Antigens; Up-Regulation | 2016 |
Characterization of a cellular immunostimulating peptide from a soybean protein fraction digested with peptidase R.
Topics: Adjuvants, Immunologic; Animals; Antigens, CD; Cell Culture Techniques; Cell Line, Tumor; Chromatography; Glutamine; Glycine max; Humans; Interferon-gamma; Interleukin-12; K562 Cells; Leukemia; Mice; Mice, Inbred C3H; Peptide Hydrolases; Peptides; Protein Subunits; Rhizopus; Soybean Proteins; Spleen | 2009 |
Asparaginases: a successful class of drugs against leukemias and lymphomas.
Topics: Antineoplastic Agents; Asparaginase; Drug Design; Energy Metabolism; Escherichia coli Proteins; Glutamine; Humans; Leukemia; Lymphoma | 2011 |
Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Glutamine; Immunologic Factors; Leukemia; Macrophage Activation; Metabolic Networks and Pathways; Metabolomics; Mice; Models, Biological; Nitric Oxide; Proteomics; Transcriptome | 2012 |
Disparate mechanisms of antifolate resistance provoked by methotrexate and its metabolite 7-hydroxymethotrexate in leukemia cells: implications for efficacy of methotrexate therapy.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line, Tumor; Drug Resistance, Neoplasm; Glutamine; Humans; Leukemia; Methotrexate | 2004 |
The effect of glutamine supplementation on hematopoietic stem cell transplant outcome in children: a case-control study.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dietary Supplements; Female; Glutamine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Postoperative Complications | 2008 |
Glutamine synthetase induction by glucocorticoids in the glucocorticoid-sensitive human leukemic cell line CEM-C7.
Topics: Bromodeoxyuridine; Cell Division; Clone Cells; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Humans; Kinetics; Leukemia; Receptors, Glucocorticoid; Steroids | 1982 |
Brain function estimated from the ratio of glutamine to homocarnosine levels in cerebrospinal fluid.
Topics: Bacterial Infections; Carnosine; Child; Child, Preschool; Dipeptides; Epilepsy; Female; Glutamine; Humans; Infant; Infant, Newborn; Leukemia; Male; Meningeal Neoplasms; Meningitis; Meningitis, Viral; Seizures, Febrile | 1983 |
Human plasma and amino acids as moderators of uptake and metabolic consequences of antifolates in WIL-2 and human leukemia cells.
Topics: Amino Acids; Blood; Cell Line; Culture Media; Deoxyuridine; Folic Acid Antagonists; Glutamine; Humans; Kinetics; Leukemia; Lymphocytes; Methotrexate; Pyrimethamine | 1981 |
Glutamine requirements for purine metabolism in leukemic lymphoblasts.
Topics: B-Lymphocytes; Cell Line; Glutamine; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Lymphocytes; Lymphocytes, Null; Purines; T-Lymphocytes | 1982 |
Enzyme therapy of cancer, future studies.
Topics: Adolescent; Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Asparaginase; Asparagine; Child; Child, Preschool; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Therapy; Enzymes; Female; Glutaminase; Glutamine; Humans; Kinetics; Leukemia; Male; Mice | 1981 |
Cell susceptibility to apoptosis by glutamine deprivation and rescue: survival and apoptotic death in cultured lymphoma-leukemia cell lines.
Topics: Apoptosis; Cell Survival; Culture Media; Energy Metabolism; Glucose; Glutamine; Humans; Leukemia; Lymphoma; Signal Transduction; Tumor Cells, Cultured | 1996 |
Extracellular glutamine level reduction enhances 5-fluorouracil cytotoxicity.
Topics: Amino Acids; Animals; Asparagine; Cell Count; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Humans; Leukemia; Leukemia P388; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1998 |
Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Aspartate-Ammonia Ligase; Aspartic Acid; Cells, Cultured; Diphosphates; Glutamine; Kidney; Leukemia; Ligases; Liver; Malonates; Mice; Pancreas; Proteins | 1979 |
Apparent heterogeneity between leukemic lymphocyte cell lines.
Topics: Biological Transport, Active; Glutamine; Glycolysis; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia; Lymphocytes; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oxygen Consumption; Polarography; Tumor Cells, Cultured | 1992 |
Growth study of lactate and ammonia double-resistant clones of HL-60 cells.
Topics: Ammonium Chloride; Cell Division; Clone Cells; Drug Resistance; Glucose; Glutamine; Humans; Kinetics; Lactates; Lactic Acid; Leukemia; Tumor Cells, Cultured | 1992 |
Study of metabolism and growth limitation of human leukemia cell lines.
Topics: Amino Acids; Ammonia; Cell Count; Cell Division; Cell Line; Culture Media; Glucose; Glutamine; Humans; Keto Acids; Leukemia; Ornithine; Pyruvates; Tumor Cells, Cultured | 1989 |
[Behavior of aminopeptidase activity in human leukemic leukocytes].
Topics: Acyltransferases; Adolescent; Adult; Aged; Aminopeptidases; Aspartic Acid; Child; Clinical Enzyme Tests; Eosinophils; Female; Glutamine; Glycine; Histocytochemistry; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Naphthols; Peptide Hydrolases | 1971 |
Ratio of glutamine aminotransferase & glutamine aminohydrolase in plasma of patients with malignant & other blood disorders.
Topics: Adult; Bone Marrow; Child; Female; Glutaminase; Glutamine; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Transaminases | 1974 |
Enzymes of glutathione synthesis in patients with myeloproliferative disorders.
Topics: Acute Disease; Cysteine; Erythrocytes; Glutamine; Glutathione; Humans; Kinetics; Leukemia; Leukemia, Myeloid; Myeloproliferative Disorders; Peptide Synthases; Polycythemia Vera; Primary Myelofibrosis | 1973 |
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase.
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Cell Nucleus; Enzyme Repression; Escherichia coli; Feedback; Glutamine; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Leukemia; Ligases; Liver; Lymphoid Tissue; Lymphoma; Lymphoma, Non-Hodgkin; Lysosomes; Mice; Microsomes; Mitochondria, Liver; Neoplasms, Experimental; Puromycin; Spleen; Stimulation, Chemical | 1968 |
Studies of resistance to L-asparaginase in human leukemia.
Topics: Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Drug Resistance; Escherichia coli; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Ligases | 1970 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
Sensitivity to L-asparaginase and amino acid metabolism.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium | 1970 |