glutamine has been researched along with Leukemia, Myeloid, Acute in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (42.86) | 24.3611 |
| 2020's | 6 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, N; Culp-Hill, R; D'Alessandro, A; Doxey, AC; Hope, K; Jayanth, P; Luc, J; Minden, MD; Nekkar Rao, PP; Reisz, JA; Roma, A; Spagnuolo, PA; Tcheng, M; Walker, S | 1 |
| Hu, C; Huang, J; Huang, X; Jin, J; Li, C; Li, X; Lin, X; Ma, Z; Mao, S; Qian, Y; Wang, J; Wei, W; Ye, W; Yin, X; Zhou, Y; Zhu, B | 1 |
| Chen, Y; Guo, Y; Hu, B; Li, N; Xiao, Y; Yu, L; Zhang, D; Zhao, Y | 1 |
| Goodridge, LD; Roma, A; Spagnuolo, PA | 1 |
| Dernie, F | 1 |
| Chen, QY; Li, QQ; Pan, SY; Wang, SQ; Zhou, W | 1 |
| D'Alessandro, A; DeGregori, J; Gregory, MA; Hansen, KC; Nemkov, T; Reisz, JA; Zaberezhnyy, V | 1 |
| Amrein, PC; Baer, MR; Bentzen, SM; Blitzer, MG; Carter-Cooper, BA; Duong, VH; Emadi, A; Fathi, AT; Imran, M; Jeng, LJB; Lapidus, RG; Law, JY; Lee, M; Li, H; Philip, S; Sausville, EA; Sewell, D; Singh, Z; Strovel, ET; Van Der Merwe, I; Yu, SL | 1 |
| Barosi, G; Campanelli, R; Catarsi, P; Massa, M; Poletto, V; Rosti, V; Vannucchi, AM; Villani, L | 1 |
| Chun, MG; Shaw, RJ | 1 |
| Auberger, P; Bardet, V; Bouscary, D; Chapuis, N; Green, AS; Ifrah, N; Jacque, N; Jacquel, A; Kosmider, O; Lacombe, C; Lambert, M; Maciel, TT; Mayeux, P; Moura, IC; Neveux, N; Poulain, L; Radford-Weiss, I; Schmitt, A; Tamburini, J; Uzunov, M; Willems, L | 1 |
| Konopleva, M; Samudio, I | 1 |
| Emadi, A; Sausville, EA; Zokaee, H | 1 |
| Goto, M; Hanamura, I; Miwa, H; Mizuno, S; Mizutani, M; Nitta, M; Shikami, M; Suganuma, K; Takahashi, M; Tsunekawa-Imai, N | 1 |
| Birsen, R; Bouscary, D; Chapuis, N; Decroocq, J; Demo, S; Hospital, MA; Jacque, N; Joseph, L; Lacombe, C; Lambert, M; Larrue, C; Maciel, TT; Mayeux, P; Meunier, G; Moura, IC; Poulain, L; Recher, C; Ronchetti, AM; Saland, E; Sarry, JE; Sujobert, P; Tamburini, J; Willems, L | 1 |
| Emadi, A | 1 |
| Brouwers-Vos, AZ; Günther, UL; Jaques, J; Koczula, KM; Pruis, M; Schuringa, JJ; Sontakke, P; Vellenga, E; Wierenga, AT | 1 |
| Baran, N; Cai, T; Chan, SM; Davis, RE; DiNardo, C; Flores, ER; Gonzalez, D; Haferlach, T; Jacamo, R; Konoplev, S; Konopleva, M; Li, W; Lodi, A; Ma, H; Majeti, R; Matre, P; Qi, Y; Samudio, I; Schimmer, AD; Su, X; Sweeney, SR; Tiziani, S; Velez, J; Wang, T | 1 |
| Cartoni, C; Cascino, A; Conversano, L; Martino, P; Micozzi, A; Muscaritoli, M; Petti, MC; Rossi-Fanelli, F | 1 |
| Ford, C; Pietsch, JB; Whitlock, JA | 1 |
| Spiers, AS; Wade, HE | 2 |
| Aledort, L; Patel, I; Puszkin, EG | 1 |
| Catovsky, D; Gill, R; Levi, S; Marshall, CJ; Matutes, E; Urbano-Ispizua, A; Wiedemann, LM | 1 |
| Kotlarek-Haus, S | 1 |
| Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
| Henderson, ES; Leventhal, BG | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
2 review(s) available for glutamine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Targeting Glutamine Metabolism as an Attractive Therapeutic Strategy for Acute Myeloid Leukemia.
Topics: Glutamine; Humans; Leukemia, Myeloid, Acute | 2023 |
Asparaginase in the treatment of non-ALL hematologic malignancies.
Topics: Antineoplastic Agents; Asparaginase; Glutamine; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute | 2014 |
3 trial(s) available for glutamine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Asparaginase Erwinia chrysanthemi effectively depletes plasma glutamine in adult patients with relapsed/refractory acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asparaginase; Dickeya chrysanthemi; Female; Glutamine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Young Adult | 2018 |
Oral glutamine in the prevention of chemotherapy-induced gastrointestinal toxicity.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Gastrointestinal Diseases; Glutamine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged | 1997 |
Bacterial glutaminase in treatment of acute leukaemia.
Topics: Acidosis; Adolescent; Adult; Aged; Alcaligenes; Asparagine; Child; Clinical Trials as Topic; Female; Glutaminase; Glutamine; Half-Life; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male | 1976 |
23 other study(ies) available for glutamine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia.
Topics: Glutamine; Humans; Leukemia, Myeloid, Acute; Oxidative Phosphorylation; Succinate Dehydrogenase | 2022 |
Glutamate dehydrogenase 1: A novel metabolic target in inhibiting acute myeloid leukaemia progression.
Topics: Animals; Cystine; Cytarabine; Glutamate Dehydrogenase; Glutamine; Glutathione; Leukemia, Myeloid, Acute; Mice | 2023 |
Reductive carboxylation of glutamine as a potential target in acute myeloid leukemia.
Topics: Cell Line, Tumor; Citric Acid Cycle; Glutamine; Humans; Leukemia, Myeloid, Acute; Oxidation-Reduction | 2023 |
Characterisation of a mitochondrial glutamine transporter provides a new opportunity for targeting glutamine metabolism in acute myeloid leukaemia.
Topics: Cell Line, Tumor; Glutamine; Humans; Leukemia, Myeloid, Acute; Mitochondrial Membrane Transport Proteins | 2021 |
[Effect of Competitive Antagonist of Transmembrane Glutamine Flux V-9302 on Apoptosis of Acute Myeloid Leukemia Cell Lines HL-60 and KG-1].
Topics: Apoptosis; Cell Proliferation; Glutamine; HL-60 Cells; Humans; Leukemia, Myeloid, Acute | 2021 |
Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.
Topics: Animals; Benzeneacetamides; Benzothiazoles; Cell Line, Tumor; Female; fms-Like Tyrosine Kinase 3; Glutamic Acid; Glutaminase; Glutamine; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, Transgenic; Phenylurea Compounds; Thiadiazoles; Xenograft Model Antitumor Assays | 2018 |
No association between the XPD Lys751Gln (rs13181) polymorphism and disease phenotype or leukemic transformation in primary myelofibrosis.
Topics: Cell Transformation, Neoplastic; Cohort Studies; Genetic Variation; Glutamine; Humans; Leukemia, Myeloid, Acute; Lysine; Phenotype; Polymorphism, Genetic; Primary Myelofibrosis; Xeroderma Pigmentosum Group D Protein | 2013 |
Cancer metabolism in breadth and depth.
Topics: Animals; Benzeneacetamides; Cell Differentiation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Glioma; Glutamine; Hematopoiesis; Humans; Imidazoles; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Metabolic Networks and Pathways; Neoplasms; Oncogene Protein p21(ras); Pancreatic Neoplasms; Phenylurea Compounds; Proto-Oncogene Proteins; ras Proteins; Sulfonamides | 2013 |
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Transport System ASC; Animals; Apoptosis; Asparaginase; Autophagy; Bacterial Proteins; Biological Transport; Cell Line, Tumor; Dickeya chrysanthemi; Drug Screening Assays, Antitumor; Escherichia coli Proteins; Female; Glutaminase; Glutamine; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Nude; Middle Aged; Minor Histocompatibility Antigens; Multiprotein Complexes; Protein Biosynthesis; RNA Interference; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays; Young Adult | 2013 |
Asparaginase unveils glutamine-addicted AML.
Topics: Animals; Female; Glutamine; Humans; Leukemia, Myeloid, Acute; Male | 2013 |
Importance of glutamine metabolism in leukemia cells by energy production through TCA cycle and by redox homeostasis.
Topics: Cell Line, Tumor; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamine; Glutathione; Glycolysis; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Oxidation-Reduction | 2014 |
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzeneacetamides; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Enzyme Inhibitors; Gene Knockdown Techniques; Glutaminase; Glutamine; Humans; Leukemia, Myeloid, Acute; Mice; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Thiadiazoles; Xenograft Model Antitumor Assays | 2015 |
Exploiting AML vulnerability: glutamine dependency.
Topics: Animals; Glutamine; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-2 | 2015 |
Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation.
Topics: Antigens, CD34; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cells, Cultured; Fetal Blood; Fusion Proteins, bcr-abl; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Hypoxia; Immunoenzyme Techniques; Infant, Newborn; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Magnetic Resonance Spectroscopy; Metabolomics; Neoplasm Proteins; Oxidative Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2016 |
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Topics: Antineoplastic Agents; Apoptosis; Benzeneacetamides; Cell Differentiation; Cell Proliferation; Energy Metabolism; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Mutation; Protein Isoforms; Sulfides; Thiadiazoles | 2016 |
Glutamine-supplemented tube feedings versus total parenteral nutrition in children receiving intensive chemotherapy.
Topics: Bone Marrow Transplantation; Enteral Nutrition; Feasibility Studies; Female; Food Additives; Glutamine; Humans; Infant; Leukemia, Myeloid, Acute; Organic Chemicals; Parenteral Nutrition, Total | 1997 |
Achromobacter L-glutaminase-L-asparaginase: human pharmacology, toxicology, and activity in acute leukemias.
Topics: Acidosis; Adolescent; Adult; Aged; Alcaligenes; Amidohydrolases; Amino Acids; Asparagine; Child; Drug Evaluation; Female; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Vomiting | 1979 |
Amino acid metabolism of platelets in leukemia.
Topics: Amino Acids; Asparagine; Aspartic Acid; Blood Platelets; Glucose; Glutamates; Glutamine; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous | 1976 |
Low frequency of ras oncogene mutations in Philadelphia-positive acute leukemia and report of a novel mutation H61 Leu in a single case.
Topics: Codon; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamine; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Mutation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transcriptional Activation | 1992 |
[Behavior of aminopeptidase activity in human leukemic leukocytes].
Topics: Acyltransferases; Adolescent; Adult; Aged; Aminopeptidases; Aspartic Acid; Child; Clinical Enzyme Tests; Eosinophils; Female; Glutamine; Glycine; Histocytochemistry; Humans; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Naphthols; Peptide Hydrolases | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Therapy of acute leukemia with drug combinations which include asparaginase.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Child; Child, Preschool; Cytarabine; Female; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Vincristine | 1971 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |