glutamine has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (37.93) | 24.3611 |
| 2020's | 18 (62.07) | 2.80 |
| Authors | Studies |
|---|---|
| English, J; Feng, H; Karantanos, T; Korm, S; Lam, A; Li, D; Liu, CT; Ritou, E; Shen, N; Shirihai, O; Xu, H; Zhang, X; Zong, WX | 1 |
| Anand, V; Andreeff, M; Arvanitis, Z; Battula, VL; El-Dana, F; Jaggupilli, A; Ly, S; Manning, HC; Nguyen, K; Piwnica-Worms, H; Piyarathna, DWB; Putluri, N; Yan, Y; Yuan, B | 1 |
| Koo, JS; Ryu, HJ | 1 |
| He, Y; Rong, L; Yi, G; Yuan, M; Zhan, T; Zhang, J; Zheng, L; Zhou, C | 1 |
| Hu, Y; Li, Y; Shi, H; Tang, Y; Wang, S; Xu, Z; Yuan, C; Zhang, J | 1 |
| Carmo, F; Martel, F; Silva, C | 1 |
| Duan, Z; Fan, D; Fu, R; Shen, S; Zhang, B; Zhu, C | 1 |
| Akar, S; Donmez-Altuntas, H; Hamurcu, Z | 1 |
| Cao, J; Choi, H; Gupta, M; Lee, HS; Mankoff, D; Pantel, A; Zhou, R | 1 |
| Balaban, S; Brown, KK; Cowley, MJ; Guan, YF; Holst, J; Hoy, AJ; Mayoh, C; Pang, A; Quek, LE; Turner, N; van Geldermalsen, M; Wahi, K; Wang, Q | 1 |
| Chang, HY; Hsia, SM; Hsu, KC; Huang, TC; Lin, JR; Lin, LC; Lin, TE | 1 |
| Rugo, HS; Vidula, N; Yau, C | 1 |
| Chen, W; Chen, X; He, J; Hong, J; Huang, O; Huang, R; Li, Y; Shen, K; Wang, H; Wang, Z; Wu, J | 1 |
| Hou, C; Liang, X; Qin, J; Wang, S; Zhang, W; Zhong, D; Zhou, C; Zhou, P; Zhu, Z | 1 |
| Alfarsi, L; Althobiti, M; Ansari, RE; Craze, ML; Ellis, IO; Green, AR; Rakha, EA | 1 |
| Abbara, A; Babwah, AV; Bech, PR; Bhattacharya, M; Brackstone, M; Clarke, S; Dhillo, WS; Dragan, M; Goertzen, C; Guzman, S; Hess, DA; Nguyen, MU; Pine, SR; Su, X; Tuck, AB; Wondisford, FE; Zong, WX | 1 |
| Baguley, BC; Dechaume, AL; Katt, WP; Leung, EY; Murray, PM; Singleton, DC | 1 |
| Craze, ML; El-Ansari, R; Fan, SJ; Goberdhan, DCI; Green, AR; Haider, S; Harris, AL; Morotti, M; Rakha, EA; Valli, A; Zois, CE | 1 |
| Boothby, MR; Chen, J; Cho, SH; Cook, RS; Edwards, DN; Hwang, Y; Kim, LC; Manning, HC; Ngwa, VM; Paik, Y; Rathmell, JC; Raybuck, AL; Wang, Q; Wang, S; Zhang, S | 1 |
| Chaika, NV; Goode, G; Gunda, V; Purohit, V; Singh, PK; Yu, F | 1 |
| Adrian, F; Arlt, H; Barberis, C; Cheng, H; Deng, G; Garcia-Escheverria, C; He, T; Hoffmann, D; Lampa, M; Murtie, J; Ospina, B; Pollard, J; Reeves, J; Richon, V; Srinivasan, L; Wiederschain, D; Winter, C; Zhang, B | 1 |
| Cerione, RA; Huang, Q; Iyer, P; Katt, WP; McDermott, LA; O'Neill, J; Reimer, S; Stalnecker, C; Zhang, C | 1 |
| López-Rivas, A; Mauro-Lizcano, M | 1 |
| Adamoski, D; Consonni, SR; Corrêa-da-Silva, F; Dias, SMG; Malta de Sá Patroni, F; Meira Dias, M; Mendes de Moraes-Vieira, PM; Ornitz Oliveira Souza, R; Reis, LMD; Rodrigues Ascenção, CF; Silber, AM; Sousa de Oliveira, KR | 1 |
| Bizjak, M; Malavašič, P; Pavlin, M; Pirkmajer, S | 1 |
| Chan, DA; Daemen, A; Ethier, SP; Gray, JW; Holton, T; Hu, M; Louie, RJ; McCormick, F; Padró, M; Polyak, K; Timmerman, LA; van 't Veer, LJ; Yuneva, M | 1 |
| Foygel, K; Ilovich, O; Paulmurugan, R; Sekar, TV | 1 |
| Bailey, CG; Beith, JM; Deng, N; Feng, Y; Gao, D; Harvey, K; Holst, J; Marshall, AD; Nagarajah, R; O'Toole, SA; Rasko, JE; Ritchie, W; Selinger, CI; Thoeng, A; van Geldermalsen, M; Wang, Q | 1 |
| Chen, L; Cui, H; Deng, H; Fang, J; Guo, H; Kuang, P; Wang, X; Zhao, L | 1 |
29 other study(ies) available for glutamine and ER-Negative PR-Negative HER2-Negative Breast Cancer
| Article | Year |
|---|---|
DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer.
Topics: Acyltransferases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Glutamine; Humans; Metabolomics; Triple Negative Breast Neoplasms | 2021 |
Metabolic stress induces GD2
Topics: Animals; Blood Glucose; Cell Line, Tumor; Female; Ferroptosis; Gangliosides; Glutamine; Humans; Metabolomics; Mice; Neoplastic Stem Cells; Phenotype; Small Molecule Libraries; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2022 |
Glucose and glutamine metabolism-related protein expression in breast ductal carcinoma in situ.
Topics: Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Female; Glucose; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; Receptor, ErbB-2; Triple Negative Breast Neoplasms | 2022 |
Circ_0062558 promotes growth, migration, and glutamine metabolism in triple-negative breast cancer by targeting the miR-876-3p/SLC1A5 axis.
Topics: Amino Acid Transport System ASC; Amino Acid Transport Systems, Neutral; Animals; Bromides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutamine; Humans; MicroRNAs; Minor Histocompatibility Antigens; RNA, Circular; Thymidine; Triple Negative Breast Neoplasms | 2022 |
Simultaneous glutamine metabolism and PD-L1 inhibition to enhance suppression of triple-negative breast cancer.
Topics: Animals; B7-H1 Antigen; Cell Line, Tumor; Glutamine; Humans; Immune Checkpoint Inhibitors; Ligands; Mice; Molybdenum; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2022 |
Inhibition of Glutamine Cellular Uptake Contributes to the Cytotoxic Effect of Xanthohumol in Triple-Negative Breast Cancer Cells.
Topics: Antineoplastic Agents; Catechin; Cell Line, Tumor; Flavonoids; Glutamine; Humans; Polyphenols; Propiophenones; Triple Negative Breast Neoplasms | 2022 |
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Ginsenosides; Glutamine; Humans; Mice; Triple Negative Breast Neoplasms | 2022 |
β-Escin reduces cancer progression in aggressive MDA-MB-231 cells by inhibiting glutamine metabolism through downregulation of c-myc oncogene.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Escin; Genes, myc; Glutamine; Humans; Triple Negative Breast Neoplasms | 2022 |
Topics: Animals; Biomarkers; Carboxylic Acids; Cyclobutanes; Glutaminase; Glutamine; Humans; Kinetics; Mice; Positron-Emission Tomography; Triple Negative Breast Neoplasms | 2023 |
Glutamine addiction promotes glucose oxidation in triple-negative breast cancer.
Topics: Cell Line, Tumor; Citric Acid Cycle; Glucose; Glutamic Acid; Glutamine; Humans; Triple Negative Breast Neoplasms | 2022 |
Structure-based virtual screening discovers novel kidney-type glutaminase inhibitors.
Topics: Cell Line, Tumor; Cell Survival; Glutaminase; Glutamine; Humans; Kidney; Triple Negative Breast Neoplasms | 2022 |
Glutaminase (GLS1) gene expression in primary breast cancer.
Topics: Breast Neoplasms; Female; Gene Expression; Glutaminase; Glutamine; Humans; Prognosis; Triple Negative Breast Neoplasms | 2023 |
Targeting glutamine metabolic reprogramming of SLC7A5 enhances the efficacy of anti-PD-1 in triple-negative breast cancer.
Topics: Animals; CD8-Positive T-Lymphocytes; Down-Regulation; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; Mice; Triple Negative Breast Neoplasms | 2023 |
Glutamine-β-cyclodextrin for targeted doxorubicin delivery to triple-negative breast cancer tumors via the transporter ASCT2.
Topics: Amino Acid Transport System ASC; Animals; Apoptosis; beta-Cyclodextrins; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Glutamine; Humans; Mice, Inbred BALB C; Mice, Nude; Minor Histocompatibility Antigens; Triple Negative Breast Neoplasms | 2019 |
Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer.
Topics: Aged; Amino Acid Transport System ASC; B7-H1 Antigen; Cell Line, Tumor; Cohort Studies; Female; Gene Knockdown Techniques; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; Lymphocytes, Tumor-Infiltrating; Macrophages; Minor Histocompatibility Antigens; Prognosis; Programmed Cell Death 1 Receptor; Signal Transduction; Transfection; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2020 |
G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer.
Topics: Adult; Aged; Animals; Carcinogenesis; Case-Control Studies; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cellular Reprogramming; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Humans; Mice, Inbred NOD; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Nucleotides; Proto-Oncogene Proteins c-myc; Receptors, Kisspeptin-1; Signal Transduction; Triple Negative Breast Neoplasms; Tumor Burden; Young Adult | 2020 |
Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer.
Topics: Benzeneacetamides; Cell Proliferation; Drug Resistance, Neoplasm; Female; Glutaminase; Glutamine; Humans; Pyruvic Acid; Thiadiazoles; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Tumor Microenvironment | 2020 |
Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer.
Topics: Adult; Aged; Amino Acid Transport System A; Cell Line, Tumor; Female; Glutamine; Humans; Middle Aged; Oxidative Stress; Prognosis; Triple Negative Breast Neoplasms | 2021 |
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Female; Glutamine; Heterografts; Humans; Immunity, Cellular; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Transgenic; Neoplasm Transplantation; Triple Negative Breast Neoplasms | 2021 |
MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Reprogramming; Chromatography, Liquid; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glutamine; Humans; Metabolome; Mucin-1; Nitrogen; Real-Time Polymerase Chain Reaction; Tandem Mass Spectrometry; Triple Negative Breast Neoplasms | 2017 |
Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition.
Topics: Cell Line, Tumor; Female; Glutaminase; Glutamine; Humans; TOR Serine-Threonine Kinases; Triple Negative Breast Neoplasms | 2017 |
Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism.
Topics: Allosteric Site; Amino Acid Substitution; Antineoplastic Agents; Benzeneacetamides; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glutaminase; Glutamine; Humans; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Mutation; Neoplasm Proteins; Recombinant Proteins; Sulfides; Thiadiazoles; Triple Negative Breast Neoplasms | 2018 |
Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells.
Topics: CASP8 and FADD-Like Apoptosis Regulating Protein; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glutamine; Humans; MCF-7 Cells; Neoplasm Proteins; TNF-Related Apoptosis-Inducing Ligand; Triple Negative Breast Neoplasms | 2018 |
Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells.
Topics: Benzeneacetamides; Carnitine O-Palmitoyltransferase; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Female; Glutaminase; Glutamine; Humans; Oxidation-Reduction; Thiadiazoles; Triple Negative Breast Neoplasms; Tumor Cells, Cultured | 2019 |
Comparison of the effects of metformin on MDA-MB-231 breast cancer cells in a monolayer culture and in tumor spheroids as a function of nutrient concentrations.
Topics: AMP-Activated Protein Kinases; Cell Culture Techniques; Cell Survival; Enzyme Activation; Female; Glucose; Glutamine; Humans; Hypoglycemic Agents; Metformin; Nutrients; Pyruvic Acid; Spheroids, Cellular; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2019 |
Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.
Topics: Amino Acid Transport System y+; Animals; Cell Line, Tumor; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamine; Glutathione; Humans; Mice; Prognosis; Reactive Oxygen Species; RNA, Small Interfering; Triple Negative Breast Neoplasms | 2013 |
Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice.
Topics: Animals; Antineoplastic Agents; Aziridines; Disease Models, Animal; Genetic Therapy; Glutamine; Lung Neoplasms; Mice; Neoplasm Metastasis; Nitroreductases; Optical Imaging; Organometallic Compounds; Prodrugs; Radiography; Thymidine Kinase; Treatment Outcome; Triple Negative Breast Neoplasms | 2014 |
ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer.
Topics: Amino Acid Transport System ASC; Animals; Cell Growth Processes; Cell Line, Tumor; Gene Expression Profiling; Gene Knockdown Techniques; Glutamine; Heterografts; Humans; Mice; Minor Histocompatibility Antigens; Neoplasms, Basal Cell; Triple Negative Breast Neoplasms | 2016 |
Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Survival; Cisplatin; Culture Media; Dose-Response Relationship, Drug; Etoposide; Female; Glutaminase; Glutamine; Humans; Immunoblotting; Sulfides; Thiadiazoles; Triple Negative Breast Neoplasms | 2016 |