glutamine and Disease Models, Animal

glutamine has been researched along with Disease Models, Animal in 459 studies

Research

Studies (459)

TimeframeStudies, this research(%)All Research%
pre-199019 (4.14)18.7374
1990's32 (6.97)18.2507
2000's145 (31.59)29.6817
2010's207 (45.10)24.3611
2020's56 (12.20)2.80

Authors

AuthorsStudies
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Guo, S; Huang, B; Jiang, S; Mao, X; Mo, C; Zhuang, J1
Aldana, BI; Andersen, JV; Christensen, SK; Diaz-delCastillo, M; Freude, KK; Gentry, MS; Haukedal, H; Kohlmeier, KA; Mann, M; Markussen, KH; Polli, FS; Schousboe, A; Shabani, M; Skotte, NH; Sun, RC; Tanila, H; Waagepetersen, HS; Westi, EW1
Beldi, VFM; Evora, PRB; Farina Junior, JA; Jordão, AA; Moriguti, EKU; Rosique, MJ; Tirapelli, DPC; Tirapelli, LF1
Burczynski, ME; Chen, H; Cheng, X; Halasz, G; Kim, S; Lin, AZ; Mao, X; Murphy, AJ; Na, E; Okamoto, H; Sleeman, MW1
Gao, Y; He, Z; Li, T; Luo, C; Ou, L; Yu, C1
Huang, Y; Ji, P; Liu, C; Liu, SJ; Wang, N; Yu, Y; Zhang, B; Zhao, F; Zuo, Z1
Adeyemi, DH; Afolabi, OA; Akhigbe, RE; Anyogu, DC; Hamed, MA; Odetayo, AF1
Chao de la Barca, JM; Eid, M; Fassot, C; Faure, J; Fouquet, O; Henrion, D; Loufrani, L; Reynier, P; Richard, A; Robert, P; Tessier, L; Wetterwald, C1
Beracochea, D; Dore, J; Dries, A; Faucher, P; Leboyer, M; Mousset, PY1
Liu, J; Song, M1
Cao, L; Fan, HT; Li, JL; Song, R; Yang, HT; Yang, XF; Zhong, L; Zhou, HX1
Almeida, GM; Ayupe, MC; Caldini, EG; Carregari, VC; Costa, L; Crunfli, F; Cunha, TM; D'Império Lima, MR; da Silva, P; Davanzo, GG; de Almeida Campos, AC; de Araújo, MV; de Oliveira, LG; de Oliveira, MG; de Sá Guimarães, AM; de Souza Angelo, Y; de Souza Filho, AF; Dos Passos Cunha, M; Dos Santos, NB; Duque, ÉA; Firmino, EM; Fonseca, DM; Góes, LGB; Martins-de-Souza, D; Minoprio, PC; Moraes-Vieira, PM; Mori, CMC; Munhoz, CD; Paiva, IM; Peron, JPS; Polonio, CM; Reis-de-Oliveira, G; Salgado, CL; Sebollela, A; Silva-Pereira, TT; Vendramini, PH; Yamamoto, P; Zanluqui, NG1
Chen, X; Craig, MC; Feng, J; Murphy, ST; Seo, Y; Yuneva, M1
Aliakbarzadeh, F; Hashemi, R; Khodagholi, F; Motamedi, F; Naderi, N; Naderi, S; Pourbadie, HG; Sayehmiri, F1
Kong, P; Liu, F; Tang, S; Wang, Q; Wu, R1
Anthony, DC; Augusto-Oliveira, M; Bayuangga, H; Claridge, TDW; Kuhle, J; Leppert, D; Palace, J; Probert, F; Sealey, M; Tanner, R; Yeo, T1
Anarat-Cappillino, G; Belanger, AJ; Gefteas, E; Geller, S; Kloss, A; Przybylska, M; Yew, NS1
Jiang, M; Jin, H; Li, Y; Lian, N; Lu, X; Mao, J; Qi, X; Qi, Y; Xi, B; Zhang, C; Zhao, F; Zhu, W1
Claeys, W; Geerts, A; Ghesquière, B; Lefere, S; Van Hoecke, L; Van Imschoot, G; Van Steenkiste, C; Van Vlierberghe, H; Van Wonterghem, E; Vandenbroucke, RE1
Brown, K; De Nardo, W; De Souza, DP; Fidelito, G; Keerthikumar, S; Niranjan, B; Taylor, RA; Watt, MJ1
Bae, SW; Cohen, AS; Geng, L; Georgiou, DK; Manning, HC; Tantawy, MN; Wang, J; Wen, X1
Cai, Z; Chen, Y; Shi, Y; Sun, Y; Wang, J; Wang, Q; Wang, W; Zhang, H; Zhang, X1
Dąbrowska-Bouta, B; Sidoryk-Węgrzynowicz, M; Strużyńska, L; Sulkowski, G1
Baek, JH; Kang, JS; Kim, HJ; Lee, DK; Song, M1
Fan, Q; Hanse, EA; Kong, M; Lowman, XH; Ruiz, BI; Wang, T; Wu, H; Yang, Y1
Butterfield, DA; Hinchie, A; Powell, DK; Ren, X; Swomley, A1
Allegri, G; Burke, KE; Cederbaum, SD; Häberle, J; Lipshutz, GS; Liu, XB; Martini, PGV; Truong, B; Zhu, X1
Bona, S; Carvalho, C; de Oliveira, CM; Dresch, DF; Guma, FCR; Marroni, NP; Martins, LAM; Medeiros, PC; Petry, ÉR; Rosa, TG; Schemitt, E; Wannmacher, CMD1
He, Y; Jin, H; Sun, Z; Wan, H; Yu, L; Zhou, H1
Aguilar, JMH; Alt, J; Blakeley, JO; Brayton, C; Dash, RP; Lam, J; Lemberg, KM; Majer, P; Nedelcovych, MT; Rais, R; Rodriguez, C; Slusher, BS; Tenora, L; Veeravalli, V; Wu, Y; Zhao, L1
Gao, Y; Guo, Y; Liu, Y; Lu, F; Piao, Y; Tan, S; Tang, Y1
Chen, C; Du, G; Gao, X; Qin, X; Tian, J; Yin, Q; Zhou, Y1
Abdelmalek, MF; Bashir, MR; Chitneni, SK; Diehl, AM; Du, K; Henao, R; Hyun, J; Moylan, CA; Naggie, S; Premont, RT; Suzuki, A; Wang, Y1
Cui, ZH; Rong, D; Shang, HQ; Wang, X; Zhang, XJ1
Barbosa, AM; Beauparlant, CJ; Carvalho, A; Cunha, C; Droit, A; Estaquier, J; Ferreira, C; Mesquita, I; Osório, NS; Saha, B; Silvestre, R; Torrado, E1
Baek, JH; Jung, S; Kang, JS; Kim, HJ; Son, H1
Huang, CC; Lee, PC; Lin, MT; Pai, MH; Wu, JM; Yang, PJ; Yeh, SL1
Braissant, O; Cudalbu, C; McLin, VA; Rackayova, V; Rougemont, AL1
Alt, J; Blue, ME; Fowler, A; Kannan, RM; Kannan, S; Khoury, ES; Rais, R; Ramireddy, RR; Sharma, A; Slusher, B; Thomas, AG; Tsukamoto, T1
Hazen, SL; Weeks, TL; Witkowski, M1
Cao, G; Deng, L; Gao, Y; Guo, C; Hao, J; Li, P; Li, Z; Song, Y; Sun, G; Tian, Y; Wang, X; Xia, X; Yin, Z; Zhang, H; Zhong, J; Zhou, W; Zhu, L1
Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; Laskin, J; Le, VH; Leach, M; Lee, BG; Lee, DF; Lee, DS; Lee, HJ; Lee, SB; Lee, YA; Lei, Y; Lekashvili, O; Lelj, F; Lemin, AS; Lemoine, J; Leuschner, R; Li, B; Li, BT; Li, C; Li, D; Li, F; Li, G; Li, H; Li, HW; Li, J; Li, M; Li, P; Li, Q; Li, S; Li, W; Li, X; Li, XY; Li, Y; Li, Z; Lian, Y; Liang, C; Liao, J; Liao, W; Liao, Y; Lin, D; Lin, W; Lin, YL; Lindbäck, J; Lindsay, AP; Ling, J; Linser, PJ; Liu, C; Liu, H; Liu, JJ; Liu, L; Liu, Q; Liu, SF; Liu, X; Liu, Y; Liu, Z; Liu, ZM; Lo Sterzo, C; Lo, ECM; Lobchuk, MM; Lodge, TP; Logotheti, S; Lonial, S; Lopes, G; Lopes, RD; Lopez, J; Lopez, SA; López-Santos, AL; López-Sendón, JL; Loring, Z; Louis, C; Lovita, AND; Lu, DZ; Lu, H; Lu, J; Lu, K; Lu, TT; Lu, Y; Luengo, A; Lum, LG; Luna, JM; Luo, L; Luo, R; Luo, T; Luo, X; Luo, Z; Lv, B; Lymperopoulos, N; Lyras, A; Lyu, Y; M Kannan, A; Ma, H; Ma, M; Ma, Q; Ma, S; Ma, WY; Ma, Y; Maalouf, E; Machado, FA; Maeda, K; Magrans, JO; Maharani, A; Maia, G; Mainwaring, RD; Maji, TK; Majumdar, K; Mannarino, MR; Mansuri, MS; Marinescu, SC; Markatos, G; Marquardt, S; Marraiki, N; Martens, C; Martínez, TJ; Marumo, K; Maruyama, H; Marwani, HM; Marzo, I; Masrati, G; Matamba, P; Mathialagan, S; Matys, J; Mayatra, JM; Mboua, PC; McArthur, T; McCrimmon, RJ; McIntosh, S; McSpadden, S; Medina-Campos, ON; Medvedovsky, AT; Mei, Z; Mekontso-Dessap, A; Menezes, AMB; Meng, J; Meng, P; Meng, Y; Menter, A; Mets, MB; Mets-Halgrimson, R; Metzger, T; Metzler-Nolte, N; Meyer, C; Mi, Y; Michailoviene, V; Mikrogeorgiou, A; Militz, H; Miller Iii, TF; Minarowska, A; Mir, S; Miron, I; Miyake, T; Moayer, F; Modi, S; Moeller, SJ; Mohamad, MN; Mohammed, EHM; Mokhonov, VV; Mondal, A; Moore, J; Moravcova, M; Mordi, IR; Mordi, NA; Mortensen, NP; Moscariello, C; Moser, J; Moynahan, ME; Mu, J; Mu, W; Mudduwa, LKB; Mukherjee, S; Mukhtar, A; Mulkey, DK; Murr, N; Mushtaq, Z; Muthuswamy, N; Mutlu, O; Muto, C; Myroforou, I; Na, KJ; Nabi, M; Nagornov, KO; Nagy, RJ; Naik, A; Nakajima, K; Nam, KT; Nam, YW; Namburath, M; Nammour, S; Namour, A; Namour, M; Nanan, S; Natsume, H; Nave, S; Naveed, A; Nazir, H; Ndubaku, C; Nedospasov, SA; Neradilek, MB; Newcomb, C; Nguépy Keubo, FR; Nguyen, M; Ning, J; Ning, Q; Noguchi, S; Nordahl, SHG; Nordfalk, KF; Norton, L; Noupoue, EM; Nouri, SS; Nowak, JK; Núñez, K; Oakes, K; Odegaard, JI; Ogorodnikova, OL; Ogunsuyi, O; Oh, HK; Oh, HR; Oh, KH; Ohgi, K; Okunade, KS; Oliveira, AG; Olorunfemi, G; Olsen, ML; Olson, BA; Omari, KW; Ondruschka, B; Orfali, R; Orkopoulos, A; Orlowski, RZ; Oser, SM; Oser, TK; Özcan, M; Padilla, V; Paeng, JC; Pajuelo-Lozano, N; Pal, SK; Palmieri, S; Palomeque, E; Pan, W; Panagiotakos, DB; Pandey, M; Pang, D; Pang, Q; Pangarah, CA; Panny, A; Paparella, A; Papirio, S; Papouskova, K; Parang, K; Park, HJ; Park, IK; Park, S; Parker, TL; Parkhomenko, A; Parmon, VN; Parsons, B; Parsons, J; Patel, PR; Patil, S; Patsourakos, NG; Patterson, KC; Pavlidis, P; Pedernera, M; Pedersen, R; Pedraza-Chaverri, J; Pellegrini, M; Peña-Chora, G; Pereira, EDM; Pereira, MADS; Peretz, A; Perez-Padilla, R; Perlman, GY; Perona, R; Petras, C; Phuntsho, S; Picada, JN; Pinder, TA; Piper, LFJ; Pirozzi, F; Pirro, M; Pleckaityte, M; Ploutz-Snyder, LL; Ploutz-Snyder, R; Pogorzelski, A; Poles, L; Postma, AA; Prager, A; Prakash, J; Punn, R; Pützer, BM; Qi, J; Qi, MC; Qi, Y; Qian, J; Qian, Y; Qiang, L; Qiu, J; Qu, Y; Rabiu, KA; Rahighi, S; Rahman, MM; Rahmani, B; Rajkumar, SV; Ramanathan, R; Raras, TYM; Rashi, Y; Rasool, G; Rathore, MG; Ratnawati, R; Ratola, N; Raucci, U; Ray, SK; Razavi, P; Razazi, K; Razek, S; Razi, SS; Reback, M; Reddy, K; Rees, DC; Reginatto, FH; Reich, H; Reis-Filho, JS; Ren, X; Ren, Y; Renner, G; Rey, G; Reymen, B; Riaz, M; Ricci, A; Richardson, PG; Richter, C; Riga, M; Ritchie, C; Rivoal, S; Roberts, W; Robson, ME; Rocha, GZ; Rodrigues, AD; Rogach, AL; Rojas, A; Rosenberg, A; Rosenberg, E; Rosenheck, RA; Roslan, K; Rothenberger, C; Rouschop, KMA; Rubagumya, F; Ryan, CM; Ryder, JW; Saad, MJA; Sacan, O; Sacchi, A; Sahebkar, A; Saini, A; Sainz, B; Sajo, EA; Sakizadeh, J; Saleh, AA; 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Hayakawa, T; Kohmura, E; Nonaka, M; Wakayama, A; Yamashita, T; Yoshimine, T1
Mitchell, A1
Alavi, K; Kato, Y; Schwartz, MZ; Yu, D1
Dudgeon, DL; Guerino, F; Remillard, RL; Yardley, JH1
Hazeki, N; Kanazawa, I; Yazawa, I1
Lloyd, DA; McAndrew, HF; Rintala, R; van Saene, HK1
Ballévre, O; Boza, JJ; Donnet, A; Fritsché, R; Gaudard-de-Weck, D; Jarret, AR; Möennoz, D; Perruisseau, G; Schiffrin, EJ; Vuichoud, J1
Buhr, HJ; Eibl, G; Foitzik, T; Hotz, HG; Kroesen, AJ; Kruschewski, M1
Eppinger, M; Lemmon, G; Miller, S; Nolan, D; Peoples, J; Prem, JT1
Bates, G1
Hanna, MK; Kudsk, KA1
O'Regan, MH; Phillis, JW; Ren, J1
Chang, T; Lu, R; Tsai, L1
Foitzik, T1
Andreassen, OA; Beal, MF; Bogdanov, MB; Dedeoglu, A; Ferrante, KL; Jenkins, BG; Kaddurah-Daouk, R1
Ballèvre, O; Boza, JJ; Gaudard-de-Weck, D; Jarret, AR; Moënnoz, D; Vuichoud, J1
Ladrière, L; Laghmich, A; Malaisse, WJ; Olivares, E; Scott, FW; Sener, A1
Fürst, P1
Jonas, CR; Ziegler, TR1
Argenzio, R; Blikslager, A; Guerrant, R; Hunt, E; Rhoads, M1
Ishibashi, N; Kaibara, A; Shirouzu, K; Yoshida, S1
Behar, KL; Rothman, DL1
Karinch, AM; Lin, CM; Pan, M; Souba, WW; Strange, R1
Ziegler, TR1
Apostol, BL; Bodai, L; Greenwald, M; Housman, DE; Jackson, GR; Kazantsev, A; Kurokawa, R; Marsh, JL; McCampbell, A; Pallos, J; Poelman, M; Schmidt, E; Steffan, JS; Thompson, LM; Zhu, YZ1
Grimble, RF1
Chang, EB; Kahana, M; Musch, MM; Ren, H; Wischmeyer, PE; Wolfson, R1
Scolapio, JS1
Campos, AC; Salvalaggio, PR1
Elvenes, OP; Irtun, O; Korvald, C; Larsen, T; Sørlie, D1
Ball, PA; Hardy, G1
Carvalho, GH; Figueiredo, AA; Gifoni, AR; Guerrant, RL; Lima, AA; Silva, EA; Soares, AM1
Karlsson, T; Nordgren, A; Wiklund, L1
Bartels, H; Bottiglieri, T; Burlingame, TG; Froestl, W; Gibson, KM; Grompe, M; Guerand, WS; Gupta, M; Hogema, BM; Jakobs, C; Schor, DS; Senephansiri, H; Snead, OC1
Hayden, LJ; Thomas, G; West, GB1
Collins, RC; Mehta, S1
Broadwater, JR; Jensen, JC; Klimberg, VS; Lang, NP; Nwokedi, E; Pappas, AA; Westbrook, KC1
Bullock, R; Butcher, SP; Chen, MH; Kendall, L; McCulloch, J1
Gunawan, S; Treiman, DM; Walton, NY1
Fujii, M; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Bland, KI; Bova, FC; Copeland, EM; Dolson, DJ; Hautamaki, RD; Kasper, M; Klimberg, VS; Mendenhall, WR; Plumley, DA; Salloum, RM1
Yamazaki, M1
Natori, Y; Okada, M; Oshima, M; Shibata, S; Shindo, N1
Godhwani, JL; Jain, P; Khanna, NK1
Tani, S1
Deriabina, TI; Savel'eva, SN1
Ching, S; Gabuzda, GJ; Rogoff, TM1
Cavanagh, JB; Kyu, MH; Zamora, AJ1
Dolowy, WC; Fitzmaurice, MA; Holcenberg, JS; Riley, V; Roberts, J; Spackman, D1
Abzug-Horowitz, S; Pinson, A; Russell, A; Statter, M1
Ljunggren, B; Schutz, H; Siesjö, BK1
Ljunggren, B; Ratcheson, RA; Siesjö, BK1
Perry, TL1
Balagura-Baruch, S; Welbourne, TC1
Cone, AL; Dierks-Ventling, C1

Reviews

30 review(s) available for glutamine and Disease Models, Animal

ArticleYear
Gut Microbiota and Cardiovascular Disease.
    Circulation research, 2020, 07-31, Volume: 127, Issue:4

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease Models, Animal; Fatty Acids, Volatile; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Glutamine; Host Microbial Interactions; Humans; Methylamines; Mice; Mice, Inbred C57BL; Signal Transduction; Thrombosis; Vasculitis

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses

2021
Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy.
    Trends in cancer, 2021, Volume: 7, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Disease Models, Animal; Drug Resistance, Neoplasm; Glutaminase; Glutamine; Humans; Neoplasms; NF-E2-Related Factor 2; Oxidative Stress; Thiadiazoles; Tumor Escape; Tumor Microenvironment

2021
Dissecting drug effects in preclinical models of impulsive choice: emphasis on glutamatergic compounds.
    Psychopharmacology, 2018, Volume: 235, Issue:3

    Topics: Animals; Choice Behavior; Delay Discounting; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Humans; Impulsive Behavior; Reinforcement, Psychology

2018
Branched-chain amino acids and ammonia metabolism in liver disease: therapeutic implications.
    Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:10

    Topics: Amino Acids, Branched-Chain; Ammonia; Animals; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Humans; Ketoglutaric Acids; Kidney; Liver Cirrhosis; Muscle, Skeletal; Phenylbutyrates

2013
PET and MR imaging of neuroinflammation in hepatic encephalopathy.
    Metabolic brain disease, 2015, Volume: 30, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Blood-Brain Barrier; Brain; Brain Edema; Cytokines; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Imidazoles; Inflammation; Isoquinolines; Magnetic Resonance Imaging; Microglia; Mitochondria; Multimodal Imaging; Neuroimaging; Portacaval Shunt, Surgical; Positron-Emission Tomography; Psychometrics; Pyrazoles; Pyrimidines; Rats

2015
The role of immunomodulators on intestinal barrier homeostasis in experimental models.
    Clinical nutrition (Edinburgh, Scotland), 2015, Volume: 34, Issue:6

    Topics: Animals; Arginine; Bifidobacterium; Citrulline; Disease Models, Animal; Epithelial Cells; Fatty Acids, Omega-3; Glutamine; Homeostasis; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Intestinal Mucosa; Lactobacillus; Linoleic Acids, Conjugated; Permeability; Probiotics; Saccharomyces; Tryptophan

2015
Critical Evaluation of the Changes in Glutamine Synthetase Activity in Models of Cerebral Stroke.
    Neurochemical research, 2015, Volume: 40, Issue:12

    Topics: Animals; Astrocytes; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Reperfusion Injury; Stroke

2015
Prevention and treatment of cancers by immune modulating nutrients.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes

2016
Neurocircuitry for modeling drug effects.
    Addiction biology, 2012, Volume: 17, Issue:5

    Topics: Algorithms; Animals; Behavior, Addictive; Brain; Corticotropin-Releasing Hormone; Disease Models, Animal; Glutamine; Humans; Neural Pathways; Neurotransmitter Agents; Norepinephrine; Rats; Receptors, GABA; Reinforcement, Psychology; Serotonin; Substance-Related Disorders; Synaptic Transmission

2012
Mutant mouse models in evaluating novel approaches to antipsychotic treatment.
    Handbook of experimental pharmacology, 2012, Issue:213

    Topics: Animals; Antipsychotic Agents; Carrier Proteins; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Mice; Nerve Tissue Proteins; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission

2012
Enteral feeding and gut atrophy.
    Current opinion in clinical nutrition and metabolic care, 2002, Volume: 5, Issue:6

    Topics: Adaptation, Physiological; Animals; Atrophy; Bacterial Translocation; Disease Models, Animal; Enteral Nutrition; Fasting; Gastrointestinal Hormones; Glutamine; Humans; Intestinal Mucosa; Rats; Swine

2002
Adaptation following intestinal resection: mechanisms and signals.
    Best practice & research. Clinical gastroenterology, 2003, Volume: 17, Issue:6

    Topics: Animals; Biomarkers; Disease Models, Animal; Epidermal Growth Factor; Glucagon-Like Peptides; Glucocorticoids; Glutamine; Growth Hormone; Humans; Insulin-Like Growth Factor I; Intestinal Absorption; Intestinal Mucosa; Intestines; Peptides; Short Bowel Syndrome

2003
Hepatocarcinogenesis tumor grading correlated with in vivo image-guided 1H-NMR spectroscopy in a rat model.
    Toxicology and applied pharmacology, 2005, Sep-01, Volume: 207, Issue:2 Suppl

    Topics: Animals; Disease Models, Animal; Glutamine; Glycine; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Inbred F344; Reference Standards

2005
[Drug-craving animal models and mechanisms].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2005, Volume: 126, Issue:1

    Topics: Acetylcholine; Animals; Cannabinoid Receptor Modulators; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine; Glutamine; Norepinephrine; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Reward; Stress, Physiological; Substance-Related Disorders

2005
Genetic mouse models of schizophrenia: from hypothesis-based to susceptibility gene-based models.
    Biological psychiatry, 2006, Jun-15, Volume: 59, Issue:12

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Genetic Predisposition to Disease; Glutamine; Mice; Models, Genetic; Schizophrenia

2006
[Advances in neurobiological understanding of schizophrenia. Perspectives for new therapeutic concepts].
    Der Nervenarzt, 2006, Volume: 77 Suppl 2

    Topics: Animals; Aspartic Acid; Brain; Carrier Proteins; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Neuregulin-1; Neurons; Neuropil; Risk Factors; Schizophrenia; Synaptic Transmission

2006
Nutrient modification of inflammatory mediator production.
    New horizons (Baltimore, Md.), 1994, Volume: 2, Issue:2

    Topics: Bacteremia; Capillary Permeability; Critical Illness; Cytokines; Dietary Fats; Digestive System Physiological Phenomena; Disease Models, Animal; Energy Metabolism; Enteral Nutrition; Glutamine; Humans; Immunocompetence; Inflammation; Parenteral Nutrition, Total; Stress, Physiological; Survival Rate

1994
Proton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?
    Digestive diseases (Basel, Switzerland), 1996, Volume: 14 Suppl 1

    Topics: Animals; Astrocytes; Brain; Choline; Cognition Disorders; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Humans; Hydrogen; Inositol; Liver Cirrhosis; Liver Transplantation; Magnetic Resonance Spectroscopy; Portasystemic Shunt, Transjugular Intrahepatic; Protons

1996
Pathogenesis of brain edema in fulminant hepatic failure.
    Progress in liver diseases, 1995, Volume: 13

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Humans; Intracranial Pressure; Sodium-Potassium-Exchanging ATPase

1995
Nutritional and pharmacological enhancement of gut-associated lymphoid tissue.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14 Suppl D

    Topics: Animals; Bacterial Translocation; Bombesin; Critical Illness; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Immunity, Mucosal; Intestinal Mucosa; Intestines; Lymphoid Tissue; Parenteral Nutrition

2000
[Pancreatitis and nutrition. Significance of the gastrointestinal tract and nutrition for septic complications].
    Zentralblatt fur Chirurgie, 2001, Volume: 126, Issue:1

    Topics: Animals; Bacterial Translocation; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Intestinal Mucosa; Pancreatitis, Acute Necrotizing; Randomized Controlled Trials as Topic; Rats; Survival Rate; Systemic Inflammatory Response Syndrome

2001
Conditionally indispensable amino acids (glutamine, cyst(e)ine, tyrosine, arginine, ornithine, taurine) in enteral feeding and the dipeptide concept.
    Nestle Nutrition workshop series. Clinical & performance programme, 2000, Volume: 3

    Topics: Amino Acids, Essential; Animals; Arginine; Cysteine; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Intestinal Mucosa; Ornithine; Taurine; Treatment Outcome; Tyrosine

2000
Potential role of glutamine administration in inflammatory bowel disease.
    Nestle Nutrition workshop series. Clinical & performance programme, 1999, Volume: 2

    Topics: Animals; Disease Models, Animal; Glutamine; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Nutrition Disorders; Oxidative Stress; Short Bowel Syndrome

1999
In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.
    The Journal of nutrition, 2001, Volume: 131, Issue:9 Suppl

    Topics: Acetates; Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Hyperammonemia; Magnetic Resonance Spectroscopy; Neurons; Nitrogen Isotopes; Rats

2001
Glutamine metabolism in sepsis and infection.
    The Journal of nutrition, 2001, Volume: 131, Issue:9 Suppl

    Topics: Animals; Antineoplastic Agents; Bacterial Infections; Biological Transport; Clinical Trials as Topic; Colon; Disease Models, Animal; Forecasting; Glutamine; Humans; Intestine, Small; Liver; Lung; Muscle, Skeletal; Neoplasms; Sepsis; Tumor Cells, Cultured

2001
Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy.
    The Journal of nutrition, 2001, Volume: 131, Issue:9 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Diarrhea; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Infusions, Intravenous; Neoplasms; Parenteral Nutrition, Total

2001
Nutritional modulation of immune function.
    The Proceedings of the Nutrition Society, 2001, Volume: 60, Issue:3

    Topics: Animals; Arginine; Cytokines; Dietary Fats, Unsaturated; Disease Models, Animal; Fatty Acids, Omega-3; Glutamine; Humans; Immunity; Inflammation; Nucleotides; Nutritional Physiological Phenomena; T-Lymphocytes

2001
Treatment of short-bowel syndrome.
    Current opinion in clinical nutrition and metabolic care, 2001, Volume: 4, Issue:6

    Topics: Animals; Colon; Dietary Carbohydrates; Disease Models, Animal; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glutamine; Growth Substances; Humans; Intestine, Small; Peptides; Short Bowel Syndrome

2001
Glutamine in pediatrics: where next?
    Nutrition (Burbank, Los Angeles County, Calif.), 2002, Volume: 18, Issue:6

    Topics: Age Factors; Animals; Child; Child, Preschool; Dietary Supplements; Digestive System; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; MEDLINE; Nutritional Requirements; Treatment Outcome

2002

Trials

3 trial(s) available for glutamine and Disease Models, Animal

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses

2021
Combined effects of bovine colostrum and glutamine in diclofenac-induced bacterial translocation in rat.
    Clinical nutrition (Edinburgh, Scotland), 2005, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Adhesion; Bacterial Translocation; Cattle; Colostrum; Diclofenac; Disease Models, Animal; Enterobacteriaceae; Glutamine; Intestinal Mucosa; Male; Milk; Organ Specificity; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2005
Glutamine supplementation in cancer patients.
    Nutrition (Burbank, Los Angeles County, Calif.), 2001, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Carbon Isotopes; Case-Control Studies; Combined Modality Therapy; Dietary Supplements; Disease Models, Animal; Esophageal Neoplasms; Glutamine; Humans; Male; Parenteral Nutrition, Total; Proteins; Rats

2001

Other Studies

427 other study(ies) available for glutamine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
LncRNA nuclear-enriched abundant transcript 1 shuttled by prostate cancer cells-secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR-205-5p/runt-related transcription factor 2/splicing factor proline- and glu
    Clinical and translational medicine, 2021, Volume: 11, Issue:8

    Topics: Animals; Bone Neoplasms; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Exosomes; Glutamine; Humans; Male; Mice; MicroRNAs; Osteoblasts; Phenotype; Polypyrimidine Tract-Binding Protein; Proline; Prostatic Neoplasms; RNA Splicing Factors; RNA, Long Noncoding; Tumor Microenvironment

2021
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease.
    Cell death & disease, 2021, 10-16, Volume: 12, Issue:11

    Topics: Alzheimer Disease; Amyloid; Animals; Astrocytes; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hippocampus; Male; Metabolome; Mice, Transgenic; Mitochondria; Neurotransmitter Agents; Proteome; Signal Transduction; Synapses

2021
Oral glutamine dipeptide or oral glutamine free amino acid reduces burned injury progression in rats.
    Brazilian journal of biology = Revista brasleira de biologia, 2021, Volume: 84

    Topics: Amino Acids; Animals; Burns; Dipeptides; Disease Models, Animal; Glutamine; Male; Rats; Rats, Wistar

2021
Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model.
    Journal of inherited metabolic disease, 2022, Volume: 45, Issue:3

    Topics: Ammonia; Animals; Disease Models, Animal; Glutaminase; Glutamine; Humans; Hyperammonemia; Liver; Mice; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Urea; Urea Cycle Disorders, Inborn

2022
HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation.
    International journal of oncology, 2022, Volume: 60, Issue:4

    Topics: Animals; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Glutamine; Male; Mice; Mice, Nude; Prostatic Neoplasms; Signal Transduction

2022
Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8
    Nature communications, 2022, 03-03, Volume: 13, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Autism Spectrum Disorder; Disease Models, Animal; Gastrointestinal Microbiome; Glutamine; Mice; Microbiota

2022
Glutamine prevents upregulation of NF-kB signaling and caspase 3 activation in ischaemia/reperfusion-induced testicular damage: An animal model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 150

    Topics: Animals; Antioxidants; Caspase 3; Disease Models, Animal; Glutamine; Humans; Ischemia; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Spermatic Cord Torsion; Testis; Up-Regulation

2022
Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr
    International journal of molecular sciences, 2022, Jun-07, Volume: 23, Issue:12

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Energy Metabolism; Glutamine; Glycine; Hypercholesterolemia; Hyperlipidemias; Lipids; Metabolomics; Mice; Mice, Inbred C57BL; Nitric Oxide; Receptors, LDL

2022
Synergistic effects of
    Beneficial microbes, 2022, Aug-03, Volume: 13, Issue:3

    Topics: Animals; Clomipramine; Curcumin; Depression; Depressive Disorder; Disease Models, Animal; Glutamine; Humans; Infant; Lacticaseibacillus rhamnosus; Mice; Probiotics; Stress, Psychological

2022
Circ_0067717 promotes colorectal cancer cell growth, invasion and glutamine metabolism by serving as a miR-497-5p sponge to upregulate SLC7A5.
    Histology and histopathology, 2023, Volume: 38, Issue:1

    Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; MicroRNAs

2023
Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways.
    Scientific reports, 2022, 07-13, Volume: 12, Issue:1

    Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Disease Models, Animal; Glutamine; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Mice; NF-kappa B; Osteoarthritis; Signal Transduction

2022
SARS-CoV-2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes.
    Journal of neurochemistry, 2022, Volume: 163, Issue:2

    Topics: Animals; Astrocytes; Carbon; COVID-19; Cricetinae; Disease Models, Animal; Glucose; Glutamine; Ketoglutaric Acids; Mesocricetus; Pyruvates; SARS-CoV-2

2022
[
    Molecular imaging, 2022, Volume: 2022

    Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Glutamine; Liver Neoplasms; Mice; Mice, Transgenic; Positron-Emission Tomography

2022
Phosphonate analog of 2-oxoglutarate regulates glutamate-glutamine homeostasis and counteracts amyloid beta induced learning and memory deficits in rats.
    Experimental gerontology, 2022, 10-15, Volume: 168

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hippocampus; Homeostasis; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Male; Maze Learning; Memory Disorders; Organophosphonates; Peptide Fragments; Rats; Rats, Wistar

2022
Hsa_circ_0003602 Contributes to the Progression of Colorectal Cancer by Mediating the miR-149-5p/SLC38A1 Axis.
    Gut and liver, 2023, 03-15, Volume: 17, Issue:2

    Topics: Amino Acid Transport System A; Animals; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Glutamine; Humans; MicroRNAs

2023
Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model.
    Journal of neuroinflammation, 2022, Oct-09, Volume: 19, Issue:1

    Topics: Allantoin; Animals; Biomarkers; Cytidine; Disease Models, Animal; Glucose; Glutamine; Humans; Intermediate Filaments; Multiple Sclerosis; Neurofilament Proteins; Rats

2022
Excretion of excess nitrogen and increased survival by loss of SLC6A19 in a mouse model of ornithine transcarbamylase deficiency.
    Journal of inherited metabolic disease, 2023, Volume: 46, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Neutral; Ammonia; Animals; Disease Models, Animal; Glutamine; Mice; Mice, Knockout; Nitrogen; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Urea

2023
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
    Acta histochemica, 2022, Volume: 124, Issue:8

    Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Fibrosis; Glutamine; Idiopathic Pulmonary Fibrosis; Lung; Lung Injury; Mice; Mice, Inbred C57BL; RNA, Small Interfering

2022
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
    Scientific reports, 2022, 10-20, Volume: 12, Issue:1

    Topics: Ammonia; Animals; Bile Acids and Salts; Bile Ducts; Brain; Choline; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Kynurenine; Liver Diseases; Mice; Microglia; Neuroinflammatory Diseases; Rats; Taurine; Tryptophan

2022
Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer.
    Molecular cancer research : MCR, 2023, 04-01, Volume: 21, Issue:4

    Topics: Animals; Disease Models, Animal; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Humans; Male; Mice; Prostatic Neoplasms

2023
Feasibility of [
    Tomography (Ann Arbor, Mich.), 2023, 02-24, Volume: 9, Issue:2

    Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; ErbB Receptors; Feasibility Studies; Glutamates; Glutaminase; Glutamine; Humans; Mice; Positron-Emission Tomography; Proto-Oncogene Proteins p21(ras)

2023
Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease.
    Redox biology, 2023, Volume: 62

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Disease Models, Animal; Glutamates; Glutamine; Mice; Mice, Transgenic; Neurons

2023
Mutant Tau protein-induced abnormalities in the Na
    Neurochemistry international, 2023, Volume: 168

    Topics: Animals; Astrocytes; Disease Models, Animal; Glutamine; Mice; Mice, Transgenic; Neurons; tau Proteins; Tauopathies

2023
Glutamine Supplementation Preserves Glutamatergic Neuronal Activity in the Infralimbic Cortex, Which Delays the Onset of Mild Cognitive Impairment in 3×Tg-AD Female Mice.
    Nutrients, 2023, Jun-19, Volume: 15, Issue:12

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; tau Proteins

2023
Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia.
    Genes, 2023, 09-19, Volume: 14, Issue:9

    Topics: Animals; Cachexia; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Glutamine; Histone Code; Histone Methyltransferases; Histones; Humans; Ketoglutaric Acids; Mice; Tumor Microenvironment; TWEAK Receptor

2023
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.
    Free radical biology & medicine, 2019, 11-01, Volume: 143

    Topics: Animals; Aspartic Acid; Biomarkers; Brain; Corpus Striatum; Disease Models, Animal; Female; Gene Knockout Techniques; Glutamine; Glutathione; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Protein Kinases; Rats; Taurine

2019
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 10-15, Volume: 116, Issue:42

    Topics: Ammonia; Animals; Arginase; Arginine; Codon; Disease Models, Animal; Glutamine; Hyperammonemia; Hyperargininemia; Lipids; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Nanoparticles; RNA, Messenger; Urea

2019
Oral glutamine supplementation attenuates inflammation and oxidative stress-mediated skeletal muscle protein content degradation in immobilized rats: Role of 70 kDa heat shock protein.
    Free radical biology & medicine, 2019, Volume: 145

    Topics: Administration, Oral; Animals; Antioxidants; Creatine Kinase; Dietary Supplements; Disease Models, Animal; Glutamine; Humans; Inflammation; Muscle, Skeletal; NF-kappa B; Oxidative Stress; Proteolysis; Rats; Rats, Wistar

2019
Guhong Injection promotes fracture healing by activating Wnt/beta-catenin signaling pathway in vivo and in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 120

    Topics: Animals; beta Catenin; Biomarkers; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Fracture Healing; Glutamine; Injections, Intraperitoneal; Osteoblasts; Osteogenesis; Plant Extracts; Rats, Sprague-Dawley; Tibia; Tibial Fractures; Wnt Signaling Pathway; Wnt3 Protein

2019
The Novel Glutamine Antagonist Prodrug JHU395 Has Antitumor Activity in Malignant Peripheral Nerve Sheath Tumor.
    Molecular cancer therapeutics, 2020, Volume: 19, Issue:2

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Glutamine; Humans; Male; Mice; Nerve Sheath Neoplasms; Prodrugs; Xenograft Model Antitumor Assays

2020
Metabolomic changes of blood plasma associated with two phases of rat OIR.
    Experimental eye research, 2020, Volume: 190

    Topics: Animals; Animals, Newborn; Biomarkers; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamine; Hyperoxia; Hypoxia; Metabolome; Metabolomics; Ornithine; Oxidative Stress; Oxygen; Proline; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinopathy of Prematurity

2020
Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics.
    Journal of ethnopharmacology, 2020, Mar-01, Volume: 249

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Humans; Liver; Male; Medicine, Chinese Traditional; Metabolomics; Protective Agents; Proton Magnetic Resonance Spectroscopy; Rats

2020
Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.
    Cellular and molecular gastroenterology and hepatology, 2020, Volume: 10, Issue:1

    Topics: Adult; Amino Acid Transport System ASC; Animals; Biomarkers; Cell Line; Cicatrix; Disease Models, Animal; Disease Progression; Female; Glutaminase; Glutamine; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Metabolomics; Mice; Middle Aged; Minor Histocompatibility Antigens; Myofibroblasts; Non-alcoholic Fatty Liver Disease; Positron-Emission Tomography

2020
Glutamine protects myocardial ischemia-reperfusion injury in rats through the PI3K/Akt signaling pathway.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Glutamine; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2020
Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis.
    PLoS neglected tropical diseases, 2020, Volume: 14, Issue:3

    Topics: Animals; Antiprotozoal Agents; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Humans; Immunologic Factors; Leishmaniasis, Visceral; Macrophages; Male; Mice, Inbred C57BL; Parasite Load; Phosphorylcholine; T-Lymphocyte Subsets; Treatment Outcome

2020
Glutamine Supplementation Prevents Chronic Stress-Induced Mild Cognitive Impairment.
    Nutrients, 2020, Mar-26, Volume: 12, Issue:4

    Topics: Animals; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Glutamine; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Stress, Psychological

2020
Antecedent Dietary Glutamine Supplementation Benefits Modulation of Liver Pyroptosis in Mice with Polymicrobial Sepsis.
    Nutrients, 2020, Apr-14, Volume: 12, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Caspase 1; Caspases, Initiator; Coinfection; Dietary Supplements; Disease Models, Animal; Gene Expression; Glutamine; Immunologic Factors; Inflammation; Liver; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Sepsis

2020
Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease.
    Scientific reports, 2020, 05-05, Volume: 10, Issue:1

    Topics: Animals; Aquaporin 4; Brain; Cholestasis; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutamine; Hepatic Encephalopathy; Hippocampus; Immunohistochemistry; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Osmosis; Rats; Rats, Wistar

2020
Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome.
    Theranostics, 2020, Volume: 10, Issue:13

    Topics: Animals; Dendrimers; Disease Models, Animal; Female; Glutamic Acid; Glutaminase; Glutamine; Male; Mice; Mice, Knockout; Microglia; Neuroglia; Neuroimmunomodulation; Oxidative Stress; Rett Syndrome

2020
GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis.
    The Journal of clinical investigation, 2020, 10-01, Volume: 130, Issue:10

    Topics: Adult; Aged; Animals; Case-Control Studies; Cell Differentiation; Disease Models, Animal; Female; Glutaminase; Glutamine; Humans; Interleukin-17; Keratinocytes; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Psoriasis; RNA, Messenger; T-Lymphocyte Subsets; Th17 Cells; Young Adult

2020
Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites.
    Scientific reports, 2020, 10-08, Volume: 10, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Energy Metabolism; Glutamates; Glutamine; Inflammation; Lipids; Lipopolysaccharides; Male; Metabolomics; Mice, Inbred Strains; Molecular Targeted Therapy; Signal Transduction; Swimming

2020
Intravenous Glutamine Administration Improves Glucose Tolerance and Attenuates the Inflammatory Response in Diet-Induced Obese Mice after Sleeve Gastrectomy.
    Nutrients, 2020, Oct-19, Volume: 12, Issue:10

    Topics: Adipose Tissue; Animals; Cytokines; Diet, High-Fat; Disease Models, Animal; Gastrectomy; Gluconeogenesis; Glucose Tolerance Test; Glutamine; Inflammation; Inflammation Mediators; Injections, Intravenous; Macrophages; Male; Mice, Inbred C57BL; Obesity

2020
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
    Neurobiology of disease, 2021, Volume: 148

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Carbon Isotopes; Disease Models, Animal; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Hippocampus; Homeostasis; Mice; Mice, Transgenic; Neurotransmitter Agents; Presenilin-1

2021
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats.
    Brain research, 2021, 02-15, Volume: 1753

    Topics: Animals; Brain; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Methionine Sulfoximine; Pilocarpine; Rats, Sprague-Dawley; Seizures

2021
Glutamine Inhibition Reduces Iatrogenic Laryngotracheal Stenosis.
    The Laryngoscope, 2021, Volume: 131, Issue:7

    Topics: Animals; Bleomycin; Collagen; Diazooxonorleucine; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression; Glutamine; Iatrogenic Disease; Injections, Intraperitoneal; Laryngostenosis; Mice; Mucous Membrane; Prospective Studies; Trachea; Tracheal Stenosis

2021
Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2021, 03-15, Volume: 206, Issue:6

    Topics: Adult; Alternaria; Animals; Asthma; Biomarkers; Blood Glucose; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cells, Cultured; Dexamethasone; Disease Models, Animal; Drug Synergism; Female; Glucose Transporter Type 1; Glutaminase; Glutamine; Healthy Volunteers; Humans; Immunosuppressive Agents; Lung; Male; Mice; Middle Aged; Primary Cell Culture; Pyroglyphidae; Th17 Cells; Th2 Cells; Young Adult

2021
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation.
    Nature communications, 2021, 02-22, Volume: 12, Issue:1

    Topics: Acids; Animals; Citric Acid Cycle; Cytokines; Disease Models, Animal; Fructose; Glucose; Glutamine; Glycolysis; Inflammation; Isotope Labeling; Lipopolysaccharides; Macrophages; Metabolic Flux Analysis; Mice, Inbred C57BL; Mitochondria; Monocytes; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Phenotype; T-Lymphocytes

2021
Effect of Intravenous Glutamine on Caspase-12 Expression in the Apoptosis of the Glomerular Epithelial Cells of Male Rats Exposed to Cisplatin.
    Asian Pacific journal of cancer prevention : APJCP, 2021, Feb-01, Volume: 22, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 12; Cisplatin; Disease Models, Animal; Epithelial Cells; Glutamine; Injections, Intravenous; Kidney Glomerulus; Male; Rats; Rats, Wistar

2021
Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.
    The Journal of pathology, 2021, Volume: 254, Issue:2

    Topics: Animals; Carbon-Nitrogen Ligases; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Computational Biology; Disease Models, Animal; Gene Knockdown Techniques; Glutamine; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Mice; Prostatectomy; Prostatic Neoplasms; Purines; Tissue Array Analysis; Up-Regulation; Xenograft Model Antitumor Assays

2021
Dose-Dependent Carbon-Dot-Induced ROS Promote Uveal Melanoma Cell Tumorigenicity via Activation of mTOR Signaling and Glutamine Metabolism.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021, Volume: 8, Issue:8

    Topics: Animals; Carbon; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Melanoma; Mice; Mice, Nude; Nanoparticles; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases; Uveal Neoplasms; Zebrafish

2021
Glutamine Supplementation Attenuates the Inflammation Caused by LPS-Induced Acute Lung Injury in Mice by Regulating the TLR4/MAPK Signaling Pathway.
    Inflammation, 2021, Volume: 44, Issue:6

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Female; Glutamine; Inflammation Mediators; Lipopolysaccharides; Lung; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Phosphorylation; Pneumonia; Signal Transduction; Toll-Like Receptor 4

2021
Hepatic cysteine sulphinic acid decarboxylase depletion and defective taurine metabolism in a rat partial nephrectomy model of chronic kidney disease.
    BMC nephrology, 2021, 07-05, Volume: 22, Issue:1

    Topics: Animals; Carboxy-Lyases; Cysteine Dioxygenase; Dietary Supplements; Disease Models, Animal; Glutamine; Humans; Liver; Male; Muscle, Skeletal; Nephrectomy; Proteinuria; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; RNA, Messenger; Taurine

2021
Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease.
    Cellular and molecular neurobiology, 2022, Volume: 42, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Female; Glucose; Glutamine; Humans; Mice; Mice, Transgenic; Retina

2022
Neuropeptide-S affects cognitive impairment and depression-like behavior on MPTP induced experimental mouse model of Parkinson’s disease
    Turkish journal of medical sciences, 2021, 12-13, Volume: 51, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cognition; Depression; Disease Models, Animal; Dopamine; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Neuropeptides; Neuroprotective Agents; Parkinson Disease, Secondary

2021
The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation in Rats with Ethanol-Induced Liver Damage.
    Nutrients, 2021, Aug-14, Volume: 13, Issue:8

    Topics: Animals; Dietary Supplements; Disease Models, Animal; Ethanol; Glutamine; Inflammation; Intestinal Mucosa; Liver; Liver Diseases, Alcoholic; Muscle Proteins; Protein Biosynthesis; Proteolysis; Rats; Rats, Wistar

2021
Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells.
    Oncotarget, 2017, Jul-25, Volume: 8, Issue:30

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Female; Gene Amplification; Gene Expression; Gene Knockdown Techniques; Genes, myc; Glutamine; Glycolysis; Heterografts; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Models, Biological; Small Cell Lung Carcinoma

2017
Effects of early enteral nutrition supplemented with collagen peptides on post-burn inflammatory responses in a mouse model.
    Food & function, 2017, May-24, Volume: 8, Issue:5

    Topics: Animals; Burns; Collagen; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Fish Proteins; Fishes; Glutamine; Humans; Interleukin-6; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Peptides; Tumor Necrosis Factor-alpha

2017
Cardiac mGluR1 metabotropic receptors in cardioprotection.
    Cardiovascular research, 2017, May-01, Volume: 113, Issue:6

    Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; Glutamine; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phenotype; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Receptors, Metabotropic Glutamate; Signal Transduction; Time Factors; Ventricular Function, Left

2017
Improvement of Antioxidant Defences and Mood Status by Oral GABA Tea Administration in a Mouse Model of Post-Stroke Depression.
    Nutrients, 2017, Apr-29, Volume: 9, Issue:5

    Topics: Affect; Animals; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Polyphenols; Reproducibility of Results; Stroke; Tea

2017
The Evaluation of BMAA Inhalation as a Potential Exposure Route Using a rat Model.
    Neurotoxicity research, 2018, Volume: 33, Issue:1

    Topics: Amino Acids, Diamino; Animals; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Inhalation Exposure; Male; Necrosis; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Tritium

2018
Metabolic Characterization of Myocardial Infarction Using GC-MS-Based Tissue Metabolomics.
    International heart journal, 2017, May-31, Volume: 58, Issue:3

    Topics: Animals; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Lactic Acid; Male; Metabolomics; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2017
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer.
    Oncotarget, 2017, Jul-25, Volume: 8, Issue:30

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Energy Metabolism; Gene Expression; Glucose; Glutamic Acid; Glutamine; Glycolysis; Heterografts; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lung Neoplasms; Mice; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Riluzole

2017
Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Oct-15, Volume: 23, Issue:20

    Topics: Animals; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cluster Analysis; Computational Biology; Disease Models, Animal; Energy Metabolism; Gene Expression Profiling; Glioblastoma; Glucose; Glutamine; Heterografts; Humans; Metabolomics; Mice; Mitochondria; Models, Biological; Phenotype

2017
Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.
    Scientific reports, 2017, 07-20, Volume: 7, Issue:1

    Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; Disease Models, Animal; Gene Expression; Glutamine; Heterografts; Humans; Immunohistochemistry; Intracellular Space; Mice; Polymers

2017
Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model.
    Investigative ophthalmology & visual science, 2017, 07-01, Volume: 58, Issue:9

    Topics: Animals; Anion Transport Proteins; Antigens, Polyomavirus Transforming; Blotting, Western; Cell Line; Cell Proliferation; Corneal Dystrophies, Hereditary; Disease Models, Animal; Endothelium, Corneal; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Ion Transport; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Real-Time Polymerase Chain Reaction; Symporters

2017
Glutamine prevents oxidative stress in a model of portal hypertension.
    World journal of gastroenterology, 2017, Jul-07, Volume: 23, Issue:25

    Topics: Animals; Antioxidants; Disease Models, Animal; Glutamine; Glutathione Peroxidase; Hypertension, Portal; Immunohistochemistry; Intestinal Mucosa; Ligation; Lipid Peroxidation; Liver; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Portal Vein; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2017
(S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats.
    Scientific reports, 2017, 08-30, Volume: 7, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Cerebrovascular Circulation; Cognitive Dysfunction; Dementia, Vascular; Disease Models, Animal; Glutamic Acid; Glutamine; Male; Neurons; Neuroprotective Agents; Nootropic Agents; Pyrrolidines; Rats; Rats, Wistar; Spatial Learning; Spatial Memory; Stereoisomerism; White Matter

2017
Influence of an ω3-fatty acid-enriched enteral diet with and without added glutamine on the metabolic response to injury in a rat model of prolonged acute catabolism.
    Nutrition (Burbank, Los Angeles County, Calif.), 2017, Volume: 42

    Topics: Acute Disease; Animals; Diet; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Male; Metabolism; Nitrogen; Rats; Rats, Sprague-Dawley; Time; Weight Gain; Wounds and Injuries

2017
Does l-glutamine-supplemented diet extenuate NO-mediated damage on myenteric plexus of Walker 256 tumor-bearing rats?
    Food research international (Ottawa, Ont.), 2017, Volume: 101

    Topics: Animals; Antioxidants; Cachexia; Carcinoma 256, Walker; Dietary Supplements; Disease Models, Animal; Glutamine; Ileum; Jejunum; Male; Myenteric Plexus; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; tert-Butylhydroperoxide; Tumor Burden

2017
TAp73 is a marker of glutamine addiction in medulloblastoma.
    Genes & development, 2017, 09-01, Volume: 31, Issue:17

    Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Heterografts; Humans; Medulloblastoma; Mice; Mitochondria; Nuclear Proteins; Survival Analysis; TOR Serine-Threonine Kinases; Treatment Outcome; Tumor Cells, Cultured; Tumor Protein p73

2017
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
    American journal of respiratory cell and molecular biology, 2018, Volume: 58, Issue:3

    Topics: Actins; Animals; Benzeneacetamides; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Enzyme Activation; Fibronectins; Glutaminase; Glutamine; Humans; Hydroxylation; Ketoglutaric Acids; Mice; Mice, Inbred C57BL; Myofibroblasts; Proline; Pulmonary Fibrosis; RNA Interference; RNA, Small Interfering; Sulfides; Thiadiazoles; TOR Serine-Threonine Kinases

2018
Altered mGluR5 binding potential and glutamine concentration in the 6-OHDA rat model of acute Parkinson's disease and levodopa-induced dyskinesia.
    Neurobiology of aging, 2018, Volume: 61

    Topics: Acute Disease; Animals; Cerebral Cortex; Disease Models, Animal; Dyskinesias; Female; Glutamine; Levodopa; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Putamen; Rats, Wistar; Receptor, Metabotropic Glutamate 5

2018
[Metabonomic analysis of the urine from rat model with abnormal sapra syndrome].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2017, Oct-28, Volume: 42, Issue:10

    Topics: Amino Acids; Animals; Citric Acid; Creatine; Disease Models, Animal; Energy Metabolism; Glutamine; Glycoproteins; Isoleucine; Leucine; Metabolomics; Phenylalanine; Rats; Rats, Wistar; Syndrome

2017
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2017, Volume: 40, Issue:4

    Topics: Animals; Cell Proliferation; Collagen Diseases; Disease Models, Animal; Energy Metabolism; Fatty Acids; Fibroblasts; Glucose; Glutamine; Glycolysis; Humans; Immune System; Mice; Oxidation-Reduction; Synovial Membrane

2017
Glutamine reduces myocardial cell apoptosis in a rat model of sepsis by promoting expression of heat shock protein 90.
    The Journal of surgical research, 2017, Volume: 220

    Topics: Animals; Apoptosis; Caspases; Disease Models, Animal; Glutamine; HSP90 Heat-Shock Proteins; Myocytes, Cardiac; Rats, Wistar; Sepsis

2017
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.
    Science signaling, 2017, Dec-05, Volume: 10, Issue:508

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Transport System ASC; Animals; Biomarkers, Tumor; Breast Neoplasms; Disease Models, Animal; DNA-Binding Proteins; Ephrin-A2; Female; Glutaminase; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Minor Histocompatibility Antigens; Muscle Proteins; Phosphoproteins; Receptor, EphA2; TEA Domain Transcription Factors; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; Tumor Cells, Cultured; YAP-Signaling Proteins

2017
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
    Nature medicine, 2018, Volume: 24, Issue:2

    Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Disease Models, Animal; Glutamine; HCT116 Cells; Humans; Mice; Minor Histocompatibility Antigens; Neoplasms; Oxidative Stress; Signal Transduction; Small Molecule Libraries

2018
Effect of parenteral glutamine supplementation combined with enteral nutrition on Hsp90 expression and Peyer's patch apoptosis in severely burned rats.
    Nutrition (Burbank, Los Angeles County, Calif.), 2018, Volume: 47

    Topics: Animals; Apoptosis; Burns; Cytokines; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; HSP90 Heat-Shock Proteins; Intestinal Mucosa; Male; Parenteral Nutrition; Peyer's Patches; Rats; Rats, Sprague-Dawley

2018
Enteral nutrition combined with glutamine promotes recovery after ileal pouch-anal anastomosis in rats.
    World journal of gastroenterology, 2018, Feb-07, Volume: 24, Issue:5

    Topics: Anastomosis, Surgical; Animals; Body Weight; Colitis, Ulcerative; Colonic Pouches; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Ileum; Intestinal Mucosa; Male; Microsurgery; Nutritional Status; Occludin; Postoperative Care; Postoperative Complications; Proctocolectomy, Restorative; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms

2018
Biochemical markers of striatal desensitization in cortical-limbic hyperglutamatergic TS- & OCD-like transgenic mice.
    Journal of chemical neuroanatomy, 2018, Volume: 89

    Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Glutamine; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Obsessive-Compulsive Disorder; Tourette Syndrome

2018
GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:8

    Topics: Animals; Cell Line; Chloroquine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; G-Protein-Coupled Receptor Kinase 2; Ganglia, Spinal; Gene Knockdown Techniques; Glutamine; Histamine; Humans; Injections, Subcutaneous; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Pruritus; Rats; RNA, Small Interfering

2018
NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host-Gut Microbiota Interactions during Inflammatory Bowel Disease.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Animals; Cells, Cultured; Clostridiales; Colitis; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Epithelial Cells; Gastrointestinal Microbiome; Glutamine; Humans; Immunity, Innate; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Veillonella

2018
The effect of FASN inhibition on the growth and metabolism of a cisplatin-resistant ovarian carcinoma model.
    International journal of cancer, 2018, 08-15, Volume: 143, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Fatty Acid Synthase, Type I; Fatty Acids; Female; Glutamine; Humans; Mice; Orlistat; Ovarian Neoplasms; Oxidation-Reduction

2018
Cerebral Multimodal Monitoring in Sepsis: An Experimental Study.
    Shock (Augusta, Ga.), 2019, Volume: 51, Issue:2

    Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Glucose; Glutamine; Hemodynamics; Intracranial Pressure; Male; Microdialysis; Sepsis; Swine

2019
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
    Cell metabolism, 2018, May-01, Volume: 27, Issue:5

    Topics: Adaptation, Physiological; Alanine; Animals; Disease Models, Animal; DNA, Mitochondrial; Energy Metabolism; Glutamine; HeLa Cells; Humans; Ketoglutaric Acids; Male; Mice; Mitochondria; Mitochondrial Myopathies; Mutation; Oxidative Phosphorylation

2018
MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.
    Science (New York, N.Y.), 2018, 04-20, Volume: 360, Issue:6386

    Topics: Amino Acid Substitution; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; Disease Models, Animal; Drug Design; Glutamine; GTP Phosphohydrolases; Humans; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Oligopeptides; Phosphorylation; Protein Kinases; Sciatic Nerve; Small Molecule Libraries; Threonine

2018
Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism.
    Cell reports, 2018, 05-15, Volume: 23, Issue:7

    Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; Brain; Disease Models, Animal; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Mice, Transgenic; Neurotransmitter Agents; Proteome

2018
Early Activation of Astrocytes does not Affect Amyloid Plaque Load in an Animal Model of Alzheimer's Disease.
    Neuroscience bulletin, 2018, Volume: 34, Issue:6

    Topics: Aldehyde Dehydrogenase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Brain; Calcium-Binding Proteins; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamine; Green Fluorescent Proteins; Humans; Ki-67 Antigen; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Nerve Tissue Proteins; Oxidoreductases Acting on CH-NH Group Donors

2018
Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii.
    International journal for parasitology, 2018, Volume: 48, Issue:12

    Topics: Adenosine Triphosphate; Animals; Brain; Carbon; Disease Models, Animal; Gene Deletion; Gluconeogenesis; Glutamine; Glycolysis; Hexokinase; Metabolic Flux Analysis; Mice; Oxidative Phosphorylation; Phosphoenolpyruvate Carboxykinase (ATP); Toxoplasma; Toxoplasmosis; Virulence

2018
Combined Enteral and Parenteral Glutamine Supplementation in Endotoxemic Swine: Effects on Portal and Systemic Circulation Levels.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2018, Volume: 27, Issue:6

    Topics: Administration, Intravenous; Animals; Dietary Supplements; Disease Models, Animal; Drug Administration Routes; Endotoxemia; Escherichia coli; Escherichia coli Infections; Female; Glutamine; Greece; Portal System; Swine; Swine Diseases

2018
GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay.
    Human molecular genetics, 2019, 01-01, Volume: 28, Issue:1

    Topics: Adolescent; Animals; Brain; Cataract; Child, Preschool; Developmental Disabilities; Disease Models, Animal; Female; Fibroblasts; Gain of Function Mutation; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; HEK293 Cells; Humans; Male; Oxidative Stress; Reactive Oxygen Species; Zebrafish

2019
Basolateral presence of the proinflammatory cytokine tumor necrosis factor -α and secretions from adipocytes and macrophages reduce intestinal sugar transport.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: Adipocytes; Animals; Caco-2 Cells; Culture Media, Conditioned; Disease Models, Animal; Down-Regulation; Glutamine; Humans; Intestinal Absorption; Intestinal Mucosa; Macrophages; Male; Methylglucosides; Mice, Inbred C57BL; Obesity; Paracrine Communication; Secretory Pathway; Signal Transduction; Sodium-Glucose Transporter 1; THP-1 Cells; Tumor Necrosis Factor-alpha

2019
Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 66, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Bacterial Agents; Ceftriaxone; Cognition; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Glutamine; Hippocampus; Maze Learning; Mice; Mice, Transgenic; Presenilin-1; Up-Regulation

2018
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Memantine; Motor Activity; Rats; Rats, Wistar; Schizophrenia; Stress, Psychological; Sucrose; Taurine

2019
MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 12-18, Volume: 115, Issue:51

    Topics: Adult; Animals; Antimalarials; Biomarkers; Blood-Brain Barrier; Brain; Brain Edema; Child; Diazooxonorleucine; Disease Models, Animal; Disease Progression; Female; Glutamine; Humans; Magnetic Resonance Imaging; Malaria, Cerebral; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Plasmodium falciparum

2018
Glutamine protects against oxidative stress injury through inhibiting the activation of PI3K/Akt signaling pathway in parkinsonian cell model.
    Environmental health and preventive medicine, 2019, Jan-05, Volume: 24, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Cell Culture Techniques; Disease Models, Animal; Glutamine; Oxidative Stress; Parkinson Disease; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Rats

2019
Sheathless CE-MS based metabolic profiling of kidney tissue section samples from a mouse model of Polycystic Kidney Disease.
    Scientific reports, 2019, 01-28, Volume: 9, Issue:1

    Topics: Animals; Betaine; Carnitine; Creatine; Creatinine; Disease Models, Animal; Electrophoresis, Capillary; Glutamine; Kidney; Mass Spectrometry; Metabolomics; Mice; Multivariate Analysis; Polycystic Kidney Diseases

2019
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
    Cell metabolism, 2019, 05-07, Volume: 29, Issue:5

    Topics: Acetates; Animals; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Child, Preschool; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Glutamine; Hepatocytes; Humans; Infant; Liver Neoplasms; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenols; Retrospective Studies; Sirolimus; TOR Serine-Threonine Kinases; Transfection; Wnt Signaling Pathway

2019
TEAD1 (TEA Domain Transcription Factor 1) Promotes Smooth Muscle Cell Proliferation Through Upregulating SLC1A5 (Solute Carrier Family 1 Member 5)-Mediated Glutamine Uptake.
    Circulation research, 2019, 04-26, Volume: 124, Issue:9

    Topics: Amino Acid Transport System ASC; Animals; Biological Transport; Cell Proliferation; Coronary Artery Disease; Disease Models, Animal; DNA-Binding Proteins; Glutamine; Humans; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Minor Histocompatibility Antigens; Myocytes, Smooth Muscle; Neointima; RNA Interference; Signal Transduction; TEA Domain Transcription Factors; Transcription Factors; Transcriptional Activation; Up-Regulation

2019
Inhibition of glutamine metabolism accelerates resolution of acute lung injury.
    Physiological reports, 2019, Volume: 7, Issue:5

    Topics: Acute Lung Injury; Amphiregulin; Animals; Anti-Inflammatory Agents; Antimetabolites; Cytokines; Diazooxonorleucine; Disease Models, Animal; Glutamine; Inflammation Mediators; Lipopolysaccharides; Lung; Macrophages; Mice, Inbred C57BL; Neutrophil Infiltration; Pneumonia; Time Factors

2019
Taurine transporter (TauT) deficiency impairs ammonia detoxification in mouse liver.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-26, Volume: 116, Issue:13

    Topics: Ammonia; Animals; Deficiency Diseases; Disease Models, Animal; GABA Plasma Membrane Transport Proteins; Gene Knockdown Techniques; Glutamate-Ammonia Ligase; Glutamine; Glycoproteins; Hepatocytes; Hyperammonemia; Inactivation, Metabolic; Kinetics; Liver; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Oxidative Stress; Perfusion; Urea

2019
In-solution behavior and protective potential of asparagine synthetase A from Trypanosoma cruzi.
    Molecular and biochemical parasitology, 2019, Volume: 230

    Topics: Ammonia; Animals; Asparagine; Aspartate-Ammonia Ligase; Chagas Disease; Chromatography, Liquid; Circular Dichroism; Disease Models, Animal; Dynamic Light Scattering; Glutamine; Mice, Inbred BALB C; Parasitemia; Protein Conformation; Protein Folding; Protozoan Vaccines; Recombinant Proteins; Trypanosoma cruzi; Vaccines, Synthetic

2019
Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-01, Volume: 25, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Energy Metabolism; Glutamine; Humans; Leukemia; Mice; Mice, Transgenic; Molecular Targeted Therapy; Oxidation-Reduction; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2019
Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice.
    Pharmaceutical biology, 2019, Volume: 57, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Glutamic Acid; Glutamine; Male; Mice, Inbred Strains; Stress, Psychological

2019
QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Animals; Cell Proliferation; Dihydropteridine Reductase; Disease Models, Animal; Gene Knockdown Techniques; Glutamine; Humans; Melanins; Neuroglia; Phenylketonurias; Zebrafish; Zebrafish Proteins

2019
Glutamine Therapy Reduces Inflammation and Extracellular Trap Release in Experimental Acute Respiratory Distress Syndrome of Pulmonary Origin.
    Nutrients, 2019, Apr-12, Volume: 11, Issue:4

    Topics: Animals; Disease Models, Animal; DNA; Endotoxins; Extracellular Traps; Female; Glutamine; Glutathione Peroxidase; Glutathione Reductase; Inflammation; Interferon-gamma; Interleukin-10; Leukocyte Count; Lung; Male; Mice, Inbred BALB C; Peroxidase; Pneumonia; Pulmonary Alveoli; Reactive Oxygen Species; Respiratory Distress Syndrome

2019
Clinical and Pathological Benefit of Twendee X in Alzheimer's Disease Transgenic Mice with Chronic Cerebral Hypoperfusion.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Behavior, Animal; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Cognition; Cystine; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neuroprotective Agents; Oxidative Stress; Plaque, Amyloid

2019
Effects of dietary glutamine supplementation on immune cell polarization and muscle regeneration in diabetic mice with limb ischemia.
    European journal of nutrition, 2020, Volume: 59, Issue:3

    Topics: Animals; Cell Polarity; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Disease Models, Animal; Glutamine; Hindlimb; Immunity; Ischemia; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Regeneration

2020
Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer.
    Breast cancer research : BCR, 2019, 05-14, Volume: 21, Issue:1

    Topics: Animals; Biomarkers; Breast Neoplasms; Cell Line, Tumor; Computational Biology; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Profiling; Glutaminase; Glutamine; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Models, Biological; Proline; Xenograft Model Antitumor Assays

2019
Labeling Cancer Stem Cells with
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1996

    Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell Hypoxia; Cell Line, Tumor; Cell Separation; Disease Models, Animal; Glucose; Glutamine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isotope Labeling; Metabolic Flux Analysis; Metabolic Networks and Pathways; Metabolomics; Mice; Neoplastic Stem Cells; Pancreatic Neoplasms; Single-Cell Analysis

2019
Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma.
    Communications biology, 2019, Volume: 2

    Topics: Animals; Body Weight; Brain; Brain Neoplasms; Caloric Restriction; Cell Line, Tumor; Cell Proliferation; Diazooxonorleucine; Diet, Ketogenic; Disease Models, Animal; Female; Fermentation; Glioblastoma; Glucose; Glutamine; Humans; Immunohistochemistry; Ketone Bodies; Ketones; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation

2019
A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice.
    Journal of visualized experiments : JoVE, 2019, 05-15, Issue:147

    Topics: Animals; Behavior, Animal; Corticosterone; Depression; Diet; Disease Models, Animal; Glutamine; Male; Mice, Inbred C57BL; Restraint, Physical; Stress, Psychological

2019
Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy.
    Journal of hepatology, 2019, Volume: 71, Issue:3

    Topics: Ammonium Compounds; Animals; Ascorbic Acid; Astrocytes; Chronic Disease; Creatine; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hippocampus; Male; Oxidative Stress; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Wistar

2019
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
    Nature metabolism, 2019, Volume: 1, Issue:1

    Topics: Animals; Biological Transport; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Male; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Binding; Pyruvic Acid; Receptors, Androgen; Signal Transduction

2019
Effect of Oral Branched-Chain Amino Acids and Glutamine Supplementation on Skeletal Muscle Atrophy After Total Gastrectomy in Rat Model.
    The Journal of surgical research, 2019, Volume: 243

    Topics: Amino Acids, Branched-Chain; Animals; Dietary Supplements; Disease Models, Animal; Gastrectomy; Glutamine; Male; Rats, Wistar; Sarcopenia

2019
Twendee X Ameliorates Phosphorylated Tau, α-Synuclein and Neurovascular Dysfunction in Alzheimer's Disease Transgenic Mice With Chronic Cerebral Hypoperfusion.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:10

    Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Ascorbic Acid; Brain; Cerebrovascular Disorders; Cystine; Dietary Supplements; Disease Models, Animal; Female; Genetic Predisposition to Disease; Glutamine; Male; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurovascular Coupling; Phenotype; Phosphorylation; tau Proteins

2019
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Mar-05, Volume: 110, Issue:10

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glutamine; Glycolysis; Hexosamines; Humans; Hypoxia; Lactic Acid; Male; Metabolic Networks and Pathways; Mice; Mice, Nude; Mice, Transgenic; Models, Biological; Pancreatic Neoplasms; Transplantation, Heterologous

2013
Effect of glutamine on apoptosis of intestinal epithelial cells of severe acute pancreatitis rats receiving nutritional support in different ways.
    International journal of clinical and experimental pathology, 2013, Volume: 6, Issue:3

    Topics: Acute Disease; Animals; Apoptosis; Combined Modality Therapy; Cytokines; Disease Models, Animal; Enteral Nutrition; Feeding Methods; Glutamine; Intestinal Mucosa; Male; Pancreas; Pancreatitis; Parenteral Nutrition; Rats; Rats, Sprague-Dawley; Taurocholic Acid

2013
The combined effects of glutamine and growth hormone on intestinal anastomosis in the rat intra-abdominal sepsis model.
    The Journal of surgical research, 2013, Jun-01, Volume: 182, Issue:1

    Topics: Administration, Oral; Anastomosis, Surgical; Animals; Disease Models, Animal; Drug Therapy, Combination; Glutamine; Growth Hormone; Hydroxyproline; Injections, Subcutaneous; Intestinal Mucosa; Intestines; Intraabdominal Infections; Male; Postoperative Complications; Rats; Rats, Sprague-Dawley; Sepsis; Wound Healing

2013
The effect of glutamine on cerebral ischaemic injury after cardiac arrest.
    Resuscitation, 2013, Volume: 84, Issue:9

    Topics: Animals; Blotting, Western; Brain; Brain Ischemia; Cardiopulmonary Resuscitation; Disease Models, Animal; Glutamine; Heart Arrest; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Statistics, Nonparametric; Tissue and Organ Harvesting

2013
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
    Nature, 2013, May-30, Volume: 497, Issue:7451

    Topics: Amino Acids; Animals; Biological Transport; Carbon; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Glutamine; Mice; Mice, Nude; NIH 3T3 Cells; Oncogene Protein p21(ras); Pancreatic Neoplasms; Pinocytosis; Proteolysis

2013
In vivo neurometabolic profiling to characterize the effects of social isolation and ketamine-induced NMDA antagonism: a rodent study at 7.0 T.
    Schizophrenia bulletin, 2014, Volume: 40, Issue:3

    Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Ketamine; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Social Isolation

2014
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.
    Cancer research, 2013, Jul-15, Volume: 73, Issue:14

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Disease Models, Animal; Glucose; Glutamine; Male; Metformin; Mice; Mice, Transgenic; Oxidation-Reduction; Prostatic Neoplasms

2013
Effects of glutamine on wound healing.
    International wound journal, 2015, Volume: 12, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Glutamine; Prognosis; Rats; Rats, Sprague-Dawley; Wound Healing; Wounds and Injuries

2015
Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
    Journal of molecular medicine (Berlin, Germany), 2013, Volume: 91, Issue:10

    Topics: Animals; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Diazooxonorleucine; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Glucose; Glutamine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Models, Biological; Oxidation-Reduction; Proto-Oncogene Proteins c-myc; Rats

2013
Dietary L-glutamine supplementation increases Pasteurella multocida burden and the expression of its major virulence factors in mice.
    Amino acids, 2013, Volume: 45, Issue:4

    Topics: Animals; Antioxidants; Cytokines; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Glutamine; Inflammation; Mice; Mice, Inbred Strains; Organ Specificity; Pasteurella; Pasteurella Infections; Toll-Like Receptors; Virulence Factors

2013
Antioxidant properties of glutamine and its role in VEGF-Akt pathways in portal hypertension gastropathy.
    World journal of gastroenterology, 2013, Jul-28, Volume: 19, Issue:28

    Topics: Animals; Antioxidants; Disease Models, Animal; Esophageal and Gastric Varices; Glutamine; Glutathione; Hypertension, Portal; Male; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Stomach; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine; Vascular Endothelial Growth Factor A

2013
Parkinson's disease: in vivo metabolic changes in the frontal and parietal cortices in 6-OHDA treated rats during different periods.
    The International journal of neuroscience, 2014, Volume: 124, Issue:2

    Topics: Animals; Aspartic Acid; Choline; Corpus Striatum; Creatine; Disease Models, Animal; Frontal Lobe; Functional Laterality; Functional Neuroimaging; Glutamates; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Motor Activity; Oxidopamine; Parietal Lobe; Parkinson Disease, Secondary; Rats; Substantia Nigra; Time Factors

2014
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors.
    Cancer discovery, 2013, Volume: 3, Issue:11

    Topics: Adenocarcinoma; Adenoma; Adenoma, Oxyphilic; Animals; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Deletion; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Lung Neoplasms; Mice; Microtubule-Associated Proteins; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins B-raf; Tumor Suppressor Protein p53

2013
Effects of enteral nutrition on the barrier function of the intestinal mucosa and dopamine receptor expression in rats with traumatic brain injury.
    JPEN. Journal of parenteral and enteral nutrition, 2015, Volume: 39, Issue:1

    Topics: Animals; Bacterial Translocation; Brain Injuries; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Mucosa; Male; Probiotics; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger

2015
Glutamine supplementation, but not combined glutamine and arginine supplementation, improves gut barrier function during chemotherapy-induced intestinal mucositis in rats.
    Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:4

    Topics: Animals; Arginine; Dietary Supplements; Disease Models, Animal; Gastrointestinal Tract; Glutamine; Immunohistochemistry; Intestines; Male; Methotrexate; Mucositis; NF-kappa B; Occludin; Rats; Rats, Sprague-Dawley; RNA, Messenger

2014
The protective effect of VSL#3 on intestinal permeability in a rat model of alcoholic intestinal injury.
    BMC gastroenterology, 2013, Oct-20, Volume: 13

    Topics: Animals; Bifidobacterium; Central Nervous System Depressants; Disease Models, Animal; Endotoxins; Ethanol; Glutamine; Intestinal Mucosa; Intestines; Lactobacillus; Liver Diseases, Alcoholic; Male; Microscopy, Electron, Transmission; Occludin; Permeability; Probiotics; Rats; Streptococcus thermophilus; Tight Junctions; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein

2013
R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer's disease.
    Brain research, 2013, Dec-06, Volume: 1541

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Flurbiprofen; Glutamic Acid; Glutamine; Hippocampus; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Maze Learning; Mice; Mice, Transgenic; tau Proteins

2013
Cancer usurps skeletal muscle as an energy repository.
    Cancer research, 2014, Jan-01, Volume: 74, Issue:1

    Topics: Amino Acids; Animals; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Energy Metabolism; Glutamine; Heterografts; HMGB1 Protein; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mitochondria, Muscle; Muscle, Skeletal; Recombinant Proteins

2014
Anticonvulsant, anxiolytic and hypnotic effects of aqueous bulb extract of Crinum glaucum A. chev (Amaryllidaceae): role of GABAergic and nitrergic systems.
    Pakistan journal of biological sciences : PJBS, 2013, Aug-01, Volume: 16, Issue:15

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Crinum; Disease Models, Animal; Enzyme Inhibitors; Female; GABA-A Receptor Antagonists; GABAergic Neurons; Glutamine; Hypnotics and Sedatives; Male; Mice; Motor Activity; Nitrergic Neurons; Nitric Oxide Synthase; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Seizures; Sleep

2013
Neuronal and astrocytic metabolism in a transgenic rat model of Alzheimer's disease.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Alzheimer Disease; Animals; Astrocytes; Brain; Citric Acid Cycle; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Neurons; Pyruvic Acid; Rats; Rats, Transgenic; Rats, Wistar

2014
Validation of the gastroschisis experimental model and the influence of the mother's diet enriched with glutamine in the fetal morphology.
    Acta cirurgica brasileira, 2014, Volume: 29, Issue:3

    Topics: Animals; Body Weight; Dietary Supplements; Disease Models, Animal; Female; Fetal Development; Fetus; Gastroschisis; Glutamine; Intestines; Organ Size; Pregnancy; Rats, Wistar; Reproducibility of Results

2014
L-glutamine supplementation prevents the development of experimental diabetic cardiomyopathy in streptozotocin-nicotinamide induced diabetic rats.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dietary Supplements; Disease Models, Animal; Electroencephalography; Glutamine; Hemodynamics; Male; Myocardium; Rats

2014
Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice.
    Theranostics, 2014, Volume: 4, Issue:5

    Topics: Animals; Antineoplastic Agents; Aziridines; Disease Models, Animal; Genetic Therapy; Glutamine; Lung Neoplasms; Mice; Neoplasm Metastasis; Nitroreductases; Optical Imaging; Organometallic Compounds; Prodrugs; Radiography; Thymidine Kinase; Treatment Outcome; Triple Negative Breast Neoplasms

2014
Glutamine protects the small intestinal mucosa in anticancer drug-induced rat enteritis model.
    The journal of medical investigation : JMI, 2014, Volume: 61, Issue:1-2

    Topics: Administration, Oral; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agents; Dietary Fiber; Disease Models, Animal; Enteritis; Fluorouracil; Glutamine; Immunoglobulin A; Intestinal Mucosa; Jejunum; Male; Oligosaccharides; Rats; Rats, Sprague-Dawley

2014
Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment.
    World journal of gastroenterology, 2014, Apr-28, Volume: 20, Issue:16

    Topics: Animals; Bacteria; Cytokines; Cytoprotection; Disease Models, Animal; Glutamine; Hypoxia; Inflammation Mediators; Intestinal Mucosa; Intestines; Male; Malondialdehyde; Myeloid Differentiation Factor 88; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Time Factors; Toll-Like Receptor 4; Transcription Factor RelA

2014
Preconditioning with glutamine protects against ischemia/reperfusion-induced hepatic injury in rats with obstructive jaundice.
    Pharmacology, 2014, Volume: 93, Issue:3-4

    Topics: Animals; Apoptosis; Disease Models, Animal; Down-Regulation; Glutamine; Glutathione; Hepatocytes; Interleukin-1beta; Jaundice, Obstructive; Liver; Male; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation

2014
A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:8

    Topics: Animals; Astrocytes; Brain; Citric Acid Cycle; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Glutamine; Kainic Acid; Lactates; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL

2014
ACVR1 p.Q207E causes classic fibrodysplasia ossificans progressiva and is functionally distinct from the engineered constitutively active ACVR1 p.Q207D variant.
    Human molecular genetics, 2014, Oct-15, Volume: 23, Issue:20

    Topics: Activin Receptors, Type I; Amino Acid Sequence; Animals; Chickens; Child; Disease Models, Animal; Genetic Variation; Glutamic Acid; Glutamine; Hindlimb; Humans; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Muscle, Skeletal; Myositis Ossificans; NIH 3T3 Cells; Point Mutation; Polymorphism, Single Nucleotide; Sequence Alignment

2014
Glutamine supplementation attenuates expressions of adhesion molecules and chemokine receptors on T cells in a murine model of acute colitis.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Acute Disease; Administration, Oral; Animals; Body Weight; Cell Adhesion Molecules; Cell Movement; Colitis; Colon; Dietary Supplements; Disease Models, Animal; Glutamine; Heparin; Intestinal Mucosa; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Polysaccharides; Receptors, CCR; Receptors, Chemokine; T-Lymphocytes

2014
Glutamine downregulates TLR-2 and TLR-4 expression and protects intestinal tract in preterm neonatal rats with necrotizing enterocolitis.
    Journal of pediatric surgery, 2014, Volume: 49, Issue:7

    Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Down-Regulation; Enterocolitis, Necrotizing; Female; Glutamine; Intestinal Mucosa; Intestines; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4

2014
In vivo 1H MRS study in microlitre voxels in the hippocampus of a mouse model of Down syndrome at 11.7 T.
    NMR in biomedicine, 2014, Volume: 27, Issue:10

    Topics: Animals; Brain Chemistry; Disease Models, Animal; Dominance, Cerebral; Down Syndrome; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neuroimaging; Nuclear Magnetic Resonance, Biomolecular; Proton Magnetic Resonance Spectroscopy

2014
Glutamine attenuates acute lung injury caused by acid aspiration.
    Nutrients, 2014, Aug-05, Volume: 6, Issue:8

    Topics: Acute Lung Injury; Administration, Intravenous; Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL1; Disease Models, Animal; Glutamine; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Pneumonia, Aspiration; Positive-Pressure Respiration; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Tidal Volume; Tumor Necrosis Factor-alpha; Ventilator-Induced Lung Injury

2014
Effects of glutamine alone on the acute necrotizing pancreatitis in rats.
    The Journal of surgical research, 2015, Volume: 193, Issue:1

    Topics: Alanine Transaminase; Amylases; Animals; Detergents; Disease Models, Animal; Glutamine; Glycodeoxycholic Acid; Interleukin-6; L-Lactate Dehydrogenase; Male; Microcirculation; Pancreas; Pancreatitis, Acute Necrotizing; Rats, Sprague-Dawley; Sodium Chloride; Treatment Outcome

2015
Glutamine prevents oxidative stress in a model of mesenteric ischemia and reperfusion.
    World journal of gastroenterology, 2014, Aug-28, Volume: 20, Issue:32

    Topics: Animals; Antioxidants; Biomarkers; Disease Models, Animal; Glutamine; Interleukin-6; Intestinal Mucosa; Intestines; Lipid Peroxidation; Lung; Lung Injury; Male; NF-kappa B; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Respiratory Mucosa; Superoxide Dismutase; Time Factors

2014
Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:11

    Topics: Animals; Biomarkers; Brain Ischemia; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Time Factors

2014
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes.
    Traffic injury prevention, 2014, Volume: 15 Suppl 1

    Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature

2014
¹H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors.
    NMR in biomedicine, 2015, Volume: 28, Issue:1

    Topics: Animals; Brain Neoplasms; Disease Models, Animal; GABAergic Neurons; Glioblastoma; Glutamine; Humans; Metabolome; Mice; Proton Magnetic Resonance Spectroscopy

2015
Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Mar-01, Volume: 21, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Electron Transport Complex I; Gene Expression; Glucose Transporter Type 4; Glutamine; Humans; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mitochondria; Multiple Myeloma; Multiprotein Complexes; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Invasiveness; Oxygen Consumption; Proto-Oncogene Proteins c-akt; Ritonavir; TOR Serine-Threonine Kinases; Tumor Burden; Xenograft Model Antitumor Assays

2015
Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.
    Journal of neurovirology, 2015, Volume: 21, Issue:2

    Topics: Alphavirus Infections; Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Diazooxonorleucine; Disease Models, Animal; Encephalitis, Viral; Enzyme-Linked Immunosorbent Assay; Glutamine; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Activity; Sindbis Virus

2015
¹H- and ¹³C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain; Carbon-13 Magnetic Resonance Spectroscopy; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Male; Mice, Transgenic; Mutation; Peptide Fragments; Phosphorylcholine; Proton Magnetic Resonance Spectroscopy

2015
Parenteral glutamine supplementation in combination with enteral nutrition improves intestinal immunity in septic rats.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:5

    Topics: Animals; Apoptosis; Body Weight; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Immunity, Mucosal; Immunoglobulin A; Intestinal Mucosa; Lymphocytes; Male; Parenteral Nutrition; Peyer's Patches; Plasma Cells; Rats; Rats, Sprague-Dawley; Sepsis; Treatment Outcome

2015
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, May-26, Volume: 112, Issue:21

    Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Genes, myc; Genes, ras; Glutaminase; Glutamine; Humans; Kidney Neoplasms; Lipid Metabolism; Mice; Mice, SCID; Mice, Transgenic; RNA, Messenger; RNA, Neoplasm; Spectrometry, Mass, Electrospray Ionization; Sulfides; Thiadiazoles; Up-Regulation

2015
Glutamine Administration After Sublethal Lower Limb Ischemia Reduces Inflammatory Reaction and Offers Organ Protection in Ischemia/Reperfusion Injury.
    JPEN. Journal of parenteral and enteral nutrition, 2016, Volume: 40, Issue:8

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Hindlimb; Inflammation; Lung; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Neutrophils; Reperfusion Injury

2016
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.
    American journal of physiology. Renal physiology, 2015, Sep-15, Volume: 309, Issue:6

    Topics: Animals; Cells, Cultured; Creatine Kinase; Disease Models, Animal; DNA Mutational Analysis; Enzyme Inhibitors; Female; Glutaminase; Glutamine; Glutarates; Humans; Infant; Infant, Newborn; Male; Metabolomics; Mice; Models, Genetic; Polycystic Kidney Diseases

2015
Glutamine ameliorates intestinal ischemia-reperfusion Injury in rats by activating the Nrf2/Are signaling pathway.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Animals; Antioxidant Response Elements; Binding Sites; Caspase 3; Cytoprotection; Disease Models, Animal; Gene Expression Regulation; Glutamine; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Jejunal Diseases; Jejunum; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Permeability; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Reperfusion Injury; Signal Transduction; Superoxide Dismutase

2015
System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.
    Immunology, 2015, Volume: 146, Issue:4

    Topics: Amino Acid Transport System A; Animals; Antibodies; Arthritis, Experimental; Cell Line, Transformed; Cell Proliferation; Collagen; Disease Models, Animal; Glutamine; Lymphocyte Activation; Male; Mice; Mice, Knockout; Nitric Oxide; Sodium; T-Lymphocytes; Up-Regulation

2015
Neuroprotective effects of Aceglutamide on motor function in a rat model of cerebral ischemia and reperfusion.
    Restorative neurology and neuroscience, 2015, Volume: 33, Issue:5

    Topics: Animals; Brain Ischemia; Cell Death; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Mesencephalon; Movement Disorders; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Treatment Outcome

2015
Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance.
    Molecular and cellular biochemistry, 2016, Volume: 411, Issue:1-2

    Topics: Administration, Oral; Animals; Diet, High-Fat; Disease Models, Animal; Glutamine; Insulin Resistance; Mice

2016
Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Animals; Bortezomib; Cell Line; Corpus Striatum; Disease Models, Animal; Glutamine; Huntingtin Protein; Huntington Disease; Mice; Nerve Tissue Proteins; Nuclear Proteins; Oligopeptides; Peptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteomics

2015
Involvement of glutamatergic neurotransmission in the antidepressant-like effect of zinc in the chronic unpredictable stress model of depression.
    Journal of neural transmission (Vienna, Austria : 1996), 2016, Volume: 123, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blotting, Western; Chlorides; Depression; Disease Models, Animal; Female; Fluoxetine; Glutamine; Hippocampus; Mice; Stress, Psychological; Synaptic Transmission; Zinc Compounds

2016
Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model.
    Behavioural brain research, 2016, Apr-15, Volume: 303

    Topics: Alcohol Drinking; Amino Acid Transport Systems, Acidic; Animals; Biogenic Monoamines; Disease Models, Animal; Dopamine; Ethanol; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Serotonin; Substance Withdrawal Syndrome

2016
Mixture of Arginine, Glutamine, and β-hydroxy-β-methyl Butyrate Enhances the Healing of Ischemic Wounds in Rats.
    JPEN. Journal of parenteral and enteral nutrition, 2017, Volume: 41, Issue:6

    Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glutamine; Hydroxyproline; Ischemia; Rats; Rats, Wistar; Valerates; Wound Healing

2017
ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.
    Cell reports, 2016, Apr-12, Volume: 15, Issue:2

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Respiration; Cytoprotection; Disease Models, Animal; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Female; Glucose; Glutamine; Humans; Imidazoles; Lactates; Mice, Inbred NOD; Mice, SCID; Mitochondria; Models, Biological; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolines; Reactive Oxygen Species; Receptors, Estrogen; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2016
Neurochemical Changes Associated with Stress-Induced Sleep Disturbance in Rats: In Vivo and In Vitro Measurements.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamine; Magnetic Resonance Imaging; Male; Radiography; Rats; Rats, Sprague-Dawley; Serotonin; Sleep Wake Disorders; Stress, Psychological; Tandem Mass Spectrometry

2016
Evaluation of a new concept of immune-enhancing diet in a model of head-injured rat with infectious complications: A proof of concept study.
    Clinical nutrition (Edinburgh, Scotland), 2016, Volume: 35, Issue:6

    Topics: Amino Acids; Animals; Antioxidants; Craniocerebral Trauma; Diet Therapy; Disease Models, Animal; Enteral Nutrition; Escherichia coli Infections; Glutamine; Humans; Immunity; Infection Control; Infections; Nutritional Requirements; Proof of Concept Study; Rats

2016
Involvement of glutamatergic N-methyl-d-aspartate receptors in the expression of increased head-dipping behaviors in the hole-board tests of olfactory bulbectomized mice.
    Behavioural brain research, 2016, 10-01, Volume: 312

    Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Frontal Lobe; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Head Movements; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Olfactory Bulb; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

2016
Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease.
    Glia, 2016, Volume: 64, Issue:11

    Topics: Animals; Astrocytes; Brain; Cyclophilin A; Disease Models, Animal; DNA-Binding Proteins; Dopamine and cAMP-Regulated Phosphoprotein 32; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Locomotion; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Nuclear Proteins

2016
Desired and side effects of the supplementation with l-glutamine and l-glutathione in enteric glia of diabetic rats.
    Acta histochemica, 2016, Volume: 118, Issue:6

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Glutamine; Glutathione; Male; Myenteric Plexus; Neuroglia; Neurons; Rats, Wistar

2016
The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.
    Molecular neurodegeneration, 2016, 08-18, Volume: 11, Issue:1

    Topics: Alzheimer Disease; Animals; Ataxia Telangiectasia; Blood Glucose; Cell Cycle Proteins; Disease Models, Animal; DNA-Binding Proteins; Glutamine; Mice, Knockout; Neurons; Neuroprotective Agents

2016
Targeting immunoproteasome and glutamine supplementation prevent intestinal hyperpermeability.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:1 Pt A

    Topics: Animals; Avoidance Learning; Colon; Dietary Supplements; Disease Models, Animal; Glutamine; Inflammation; Intestinal Mucosa; Intestines; Male; Mice, Inbred C57BL; Occludin; Permeability; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Trinitrobenzenesulfonic Acid

2017
Intravenous Glutamine Administration Modulates TNF-α/IL-10 Ratio and Attenuates NFkB Phosphorylation in a Protein Malnutrition Model.
    Inflammation, 2016, Volume: 39, Issue:6

    Topics: Animals; Disease Models, Animal; Glutamine; Interleukin-10; Mice; Mice, Inbred BALB C; NF-kappa B; Peritoneum; Phosphorylation; Protein-Energy Malnutrition; Tumor Necrosis Factor-alpha

2016
Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock.
    The journal of trauma and acute care surgery, 2016, Volume: 81, Issue:6

    Topics: Animals; Brain; Disease Models, Animal; Glutamine; Liver; Lung; Myocardium; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Succinic Acid

2016
Protective effect of L-glutamine against diabetes-induced nephropathy in experimental animal: Role of KIM-1, NGAL, TGF-β1, and collagen-1.
    Renal failure, 2016, Volume: 38, Issue:9

    Topics: Acute-Phase Proteins; Animals; Cell Adhesion Molecules; Collagen Type I; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glutamine; Lipocalin-2; Lipocalins; Male; Proto-Oncogene Proteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transforming Growth Factor beta1

2016
Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
    Neoplasia (New York, N.Y.), 2016, Volume: 18, Issue:11

    Topics: Adaptation, Biological; Amino Acids; Animals; Aspartate-Ammonia Ligase; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Female; Glutamine; Heterografts; Humans; Mice; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Burden

2016
Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models.
    BMC cancer, 2016, 10-26, Volume: 16, Issue:1

    Topics: Animals; Autophagy; Cell Line, Tumor; Disease Models, Animal; Female; Glucose; Glutamates; Glutamine; Glycolysis; Heterografts; Humans; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Mice; Mitochondria; Ovarian Neoplasms; Oxidative Stress; Positron Emission Tomography Computed Tomography; rho GTP-Binding Proteins

2016
Enzyme activities involved in the glutamate-glutamine cycle are altered to reduce glutamate after spinal cord injury in rats.
    Neuroreport, 2016, Dec-14, Volume: 27, Issue:18

    Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme Activation; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors

2016
Glutamine Prevents Late-Phase Anaphylaxis via MAPK Phosphatase 1-Dependent Cytosolic Phospholipase A2 Deactivation.
    International archives of allergy and immunology, 2016, Volume: 171, Issue:1

    Topics: Anaphylaxis; Animals; Disease Models, Animal; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Glutamine; Leukotriene B4; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Phosphorylation; Platelet Activating Factor; RNA, Small Interfering

2016
Metabolic fate of glucose in rats with traumatic brain injury and pyruvate or glucose treatments: A NMR spectroscopy study.
    Neurochemistry international, 2017, Volume: 102

    Topics: Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Male; Pyruvic Acid; Rats, Sprague-Dawley

2017
Early Administration of Glutamine Protects Cardiomyocytes from Post-Cardiac Arrest Acidosis.
    BioMed research international, 2016, Volume: 2016

    Topics: Acidosis; Animals; Cells, Cultured; Disease Models, Animal; Glutamine; Heart Arrest; Humans; Hydrogen-Ion Concentration; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Rats; Rats, Wistar

2016
Effect of Previous High Glutamine Infusion on Inflammatory Mediators and Mortality in an Acute Pancreatitis Model.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Acute Disease; Animals; Cytokines; Disease Models, Animal; Glutamine; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Inflammation; Infusions, Intravenous; Interferon-gamma; Liver; Lung; Male; Pancreatitis; Rats; Rats, Inbred Lew; Taurocholic Acid; Time Factors

2016
Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development.
    Scientific reports, 2017, 02-20, Volume: 7

    Topics: Animals; Chlorides; Dentate Gyrus; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamine; Mice; Neural Inhibition; Neurons

2017
MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.
    EMBO reports, 2017, Volume: 18, Issue:4

    Topics: Animals; Cell Line, Tumor; Cluster Analysis; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Glutamine; Glutathione; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Transgenic; MicroRNAs; Oxidative Stress; Proto-Oncogene Proteins c-myc; RNA Interference

2017
Modeling human methamphetamine use patterns in mice: chronic and binge methamphetamine exposure, reward function and neurochemistry.
    Addiction biology, 2018, Volume: 23, Issue:1

    Topics: Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Glutamine; Methamphetamine; Mice; Reward; Self Stimulation; Serotonin

2018
Parachlorophenylalanine-induced 5-HT depletion alters behavioral and brain neurotransmitters levels in 6-Hz psychomotor seizure model in mice.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:4

    Topics: Animals; Brain; Disease Models, Animal; Electroshock; gamma-Aminobutyric Acid; Glutamine; Male; Mice; Neurotransmitter Agents; Phenylalanine; Psychomotor Agitation; Seizures; Serotonin; Valproic Acid

2017
L-Gln and L-Ser suppress the D-galactosamine-induced IL-18 expression and hepatitis.
    Biochemical and biophysical research communications, 2008, Aug-08, Volume: 372, Issue:4

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Diet; Disease Models, Animal; Galactosamine; Glutamine; Interleukin-18; Male; Rats; Rats, Wistar; RNA, Messenger; Serine; Transaminases

2008
The androgen receptor's CAG/glutamine tract in mouse models of neurological disease and cancer.
    Journal of Alzheimer's disease : JAD, 2008, Volume: 14, Issue:2

    Topics: Alleles; Animals; Crosses, Genetic; Disease Models, Animal; Gene Targeting; Genetic Predisposition to Disease; Glutamine; Humans; Male; Mice; Mice, Knockout; Mice, Transgenic; Motor Neurons; Muscle, Skeletal; Muscular Atrophy, Spinal; Phenotype; Prostatic Neoplasms; Receptors, Androgen; Spinal Cord; Trinucleotide Repeats

2008
Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Glutamine; GTP-Binding Proteins; Guanosine Diphosphate; Hypertension; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neuronal Plasticity; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-B; Staining and Labeling; Sympathetic Nervous System; Synaptic Transmission; Thionucleotides

2008
Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis.
    Inflammatory bowel diseases, 2008, Volume: 14, Issue:11

    Topics: Analysis of Variance; Animals; Blotting, Western; Colitis; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glutamine; Inflammation Mediators; Male; Manometry; NF-kappa B; Oxidative Stress; Probability; Random Allocation; Rats; Sensitivity and Specificity; Signal Transduction; Statistics, Nonparametric; Transcription, Genetic; Trinitrobenzenesulfonic Acid; Up-Regulation

2008
[The different effects of glutamine on macrophage cytokines release in vivo and in vitro].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2008, Volume: 20, Issue:8

    Topics: Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Glutamine; HSP72 Heat-Shock Proteins; Interleukin-10; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Random Allocation; Sepsis; Tumor Necrosis Factor-alpha

2008
Glutamatergic inputs to the CVLM independent of the NTS promote tonic inhibition of sympathetic vasomotor tone in rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:4

    Topics: Animals; Baroreflex; Blood Pressure; Blood Vessels; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Glutamine; Hypotension; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Nitroprusside; Rats; Rats, Sprague-Dawley; Respiratory Center; Solitary Nucleus; Splanchnic Nerves; Sympathetic Nervous System; Time Factors; Vagotomy

2008
miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis.
    Nature neuroscience, 2008, Volume: 11, Issue:10

    Topics: Animals; Ataxin-1; Ataxins; Cell Line, Transformed; Cerebellum; Disease Models, Animal; Gene Expression Regulation; Glutamine; Green Fluorescent Proteins; Humans; Mice; Mice, Transgenic; MicroRNAs; Nerve Tissue Proteins; Nuclear Proteins; Phenylalanine; Purkinje Cells; RNA, Small Interfering; Spinocerebellar Ataxias; Time Factors; Transfection; Trinucleotide Repeat Expansion

2008
Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-05, Volume: 28, Issue:45

    Topics: Age Factors; Amidohydrolases; Animals; Animals, Newborn; Aspartic Acid; Axons; Behavior, Animal; Canavan Disease; Central Nervous System; Chromosome Mapping; Codon, Nonsense; Disease Models, Animal; Disease Progression; Glutamine; Lipid Metabolism; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Sheath; N-Acylsphingosine Galactosyltransferase; Oligodendroglia

2008
Neurochemical changes in a mouse model of Rett syndrome: changes over time and in response to perinatal choline nutritional supplementation.
    Journal of neurochemistry, 2009, Volume: 108, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Aspartic Acid; Brain; Choline; Creatine; Dietary Supplements; Disease Models, Animal; DNA-Binding Proteins; Glutamic Acid; Glutamine; Histone Deacetylases; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Nootropic Agents; Rett Syndrome; Spectrum Analysis

2009
Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes.
    Glycoconjugate journal, 2009, Volume: 26, Issue:2

    Topics: Animals; Burns; CD11b Antigen; Cell Adhesion; Disease Models, Animal; Endothelial Cells; Glutamine; Humans; Lactose; Leukocytes; Male; Oligosaccharides; Propanolamines; Rats; Rats, Sprague-Dawley; Shock; Time Factors; Transfection

2009
[Effects of glutamine on changes of nuclear factor-kappa B in acute lipopolysaccharide lung injury: experiment with rats].
    Zhonghua yi xue za zhi, 2008, Jun-17, Volume: 88, Issue:23

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glutamine; Lipopolysaccharides; Lung; Male; Malondialdehyde; NF-kappa B; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2008
Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia.
    Metabolic brain disease, 2009, Volume: 24, Issue:1

    Topics: Ammonia; Animals; Astrocytes; Brain; Carbon Radioisotopes; Cells, Cultured; Cholestasis; Citric Acid Cycle; Disease Models, Animal; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Isoleucine; Muscle, Skeletal; Neurons; Rats; Rats, Wistar

2009
Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:2

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Bacterial Translocation; Body Weight; Cells, Cultured; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Eating; Feces; Flagellin; Glutamine; Immunoglobulin A, Secretory; Intestines; Lymph Nodes; Male; Membrane Proteins; Metronidazole; Neomycin; Occludin; Phosphoproteins; Plasma Cells; Polymyxin B; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome; Tight Junctions; Time Factors; Zonula Occludens-1 Protein

2009
Glutamine in acute lung injury: the experimental model matters.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:3

    Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Glutamine; Heat-Shock Proteins; Lipopolysaccharides; Mice; Thiobarbituric Acid Reactive Substances

2009
Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.
    Epilepsia, 2009, Volume: 50, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoisobutyric Acids; Animals; Bicuculline; Disease Models, Animal; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamine; In Vitro Techniques; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2009
Different effect of glutamine on macrophage tumor necrosis factor-alpha release and heat shock protein 72 expression in vitro and in vivo.
    Acta biochimica et biophysica Sinica, 2009, Volume: 41, Issue:2

    Topics: Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Heat-Shock Response; HSP72 Heat-Shock Proteins; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Sepsis; Tumor Necrosis Factor-alpha

2009
Glutamine attenuates lipopolysaccharide-induced acute lung injury.
    Nutrition (Burbank, Los Angeles County, Calif.), 2009, Volume: 25, Issue:6

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Buthionine Sulfoximine; CD11b Antigen; CD18 Antigens; Disease Models, Animal; Glutamine; Glutathione; Inflammation; Interleukin-8; Lipopolysaccharides; Lung; Male; Neutrophils; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley

2009
Glutamine decreases inflammation in infant rat endotoxemia.
    Journal of pediatric surgery, 2009, Volume: 44, Issue:3

    Topics: Animals; Animals, Newborn; Cytokines; Disease Models, Animal; Endotoxemia; Escherichia coli; Escherichia coli Infections; Glutamine; Hepatocytes; Inflammation; Injections, Intraperitoneal; Interleukin-10; Lipid Peroxidation; Mitochondria, Liver; Nitric Oxide; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2009
Protective effects of glutamine dipeptide and alpha-tocopherol against ischemia-reperfusion injury in the isolated rat liver.
    Clinical nutrition (Edinburgh, Scotland), 2009, Volume: 28, Issue:3

    Topics: alpha-Tocopherol; Animals; Dipeptides; Disease Models, Animal; Drug Combinations; Glutamine; Glutathione; Liver; Male; Nitric Oxide; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

2009
Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Apr-22, Volume: 29, Issue:16

    Topics: Animals; Asparagine; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Intranuclear Inclusion Bodies; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Structure, Tertiary; Protein Transport; RNA-Binding Proteins; Solubility

2009
The preliminary experimental and clinical study of the relationship between the pigment gallstone and intestinal mucosal barrier.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:8

    Topics: Amine Oxidase (Copper-Containing); Animals; Bacterial Translocation; Bile; Bile Pigments; Case-Control Studies; Cholesterol; Disease Models, Animal; Endotoxins; Female; Gallstones; Glucuronidase; Glutamine; Guinea Pigs; Humans; Intestinal Mucosa; Lactulose; Lymph Nodes; Male; Mannitol; Permeability; Pilot Projects; Radiopharmaceuticals; Technetium Tc 99m Pentetate

2009
Roux-en-Y gastric bypass alters small intestine glutamine transport in the obese Zucker rat.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:3

    Topics: Amino Acid Transport Systems, Neutral; Animals; Biological Transport; Disease Models, Animal; Gastric Bypass; Gluconeogenesis; Glucose-6-Phosphatase; Glutaminase; Glutamine; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Up-Regulation

2009
Glutamine attenuates hyperoxia-induced acute lung injury in mice.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:1

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Edema; Glutamine; Heat-Shock Proteins; Hyperoxia; Lung; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Organ Size; Peroxidase; Random Allocation; Survival Analysis

2010
Attenuation of lipopolysaccharide-mediated left ventricular dysfunction by glutamine preconditioning.
    The Journal of surgical research, 2010, May-15, Volume: 160, Issue:2

    Topics: Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Glutamine; Heart Rate; HSP72 Heat-Shock Proteins; Ischemic Preconditioning, Myocardial; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Quercetin; Ventricular Dysfunction, Left

2010
[Changes in expressions of the myocardial Toll-like receptor 4, tumor necrosis factor-alpha and interleukin-6 mRNA in rat with sepsis].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2009, Volume: 21, Issue:8

    Topics: Animals; Apoptosis; Disease Models, Animal; Glutamine; Interleukin-6; Male; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2009
Glutamine supplementation does not improve protein synthesis rate by the jejunal mucosa of the malnourished rat.
    Nutrition research (New York, N.Y.), 2009, Volume: 29, Issue:8

    Topics: Amino Acids; Animals; Body Weight; Carbon Isotopes; Dietary Supplements; Disease Models, Animal; Glutamine; Intestinal Mucosa; Jejunum; Leucine; Male; Nitrogen; Protein Biosynthesis; Protein-Energy Malnutrition; Random Allocation; Rats; Rats, Wistar; Reference Values

2009
Effects of glutamine added to enteral nutrition on Peyer's patch apoptosis in severely burned mice.
    Burns : journal of the International Society for Burn Injuries, 2010, Volume: 36, Issue:3

    Topics: Animals; Apoptosis; Burns; Caspase 3; Disease Models, Animal; Drug Evaluation, Preclinical; Enteral Nutrition; Fas Ligand Protein; Gene Expression Regulation; Glutamine; Lymphocyte Subsets; Male; Mice; Mice, Inbred BALB C; Peyer's Patches; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2010
Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation.
    The European journal of neuroscience, 2009, Volume: 30, Issue:11

    Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Biomarkers; Brain; Creatine; Disease Models, Animal; Glutamic Acid; Glutamine; In Vitro Techniques; Inositol; Linear Models; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Protons; Spectrum Analysis; Superoxide Dismutase

2009
Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS.
    Journal of the neurological sciences, 2010, Mar-15, Volume: 290, Issue:1-2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Corpus Striatum; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Humans; Kaplan-Meier Estimate; Magnetic Resonance Spectroscopy; Methionine Sulfoximine; Mice; Mice, Transgenic; Motor Cortex; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Treatment Outcome

2010
Reduction of liver ischemia-reperfusion injury via glutamine pretreatment.
    The Journal of surgical research, 2011, Volume: 166, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dipeptides; Disease Models, Animal; Glutamine; In Situ Nick-End Labeling; Ischemic Preconditioning; Laser-Doppler Flowmetry; Liver Circulation; Liver Diseases; Male; Microcirculation; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury

2011
Protective effect of glutamine-enriched early enteral nutrition on intestinal mucosal barrier injury after liver transplantation in rats.
    American journal of surgery, 2010, Volume: 199, Issue:1

    Topics: Animals; Bacterial Translocation; Biomarkers; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Enteral Nutrition; Glutamine; Immunohistochemistry; Intestinal Diseases; Intestinal Mucosa; Lactic Acid; Liver Transplantation; Male; Malondialdehyde; Polymerase Chain Reaction; Postoperative Complications; Probability; Random Allocation; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha

2010
Proteasomal degradation of glutamine synthetase regulates schwann cell differentiation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jan-27, Volume: 30, Issue:4

    Topics: Animals; Animals, Newborn; Carrier Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamine; Humans; Mice; Myelin Sheath; Nerve Regeneration; Oxidative Stress; Peripheral Nervous System Diseases; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schwann Cells; Ubiquitin-Protein Ligases

2010
Different alterations in rat intestinal glutamine transport during the progression of CLP- and LPS-induced sepsis.
    The Journal of surgical research, 2011, Volume: 169, Issue:2

    Topics: Animals; Biological Transport; Carrier Proteins; Cecum; Disease Models, Animal; Glutamine; Interleukin-10; Intestinal Mucosa; Intestines; Ligation; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha

2011
Desipramine attenuates forced swim test-induced behavioral and neurochemical alterations in mice: an in vivo(1)H-MRS study at 9.4T.
    Brain research, 2010, Aug-12, Volume: 1348

    Topics: Animals; Behavior, Animal; Brain Chemistry; Choline; Creatine; Desipramine; Disease Models, Animal; Enzyme Inhibitors; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphocreatine; Prefrontal Cortex; Protons; Stress, Psychological; Swimming

2010
The effects of oral glutamine on cyclophosphamide-induced nephrotoxicity in rats.
    Human & experimental toxicology, 2011, Volume: 30, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Disease Models, Animal; Glutamine; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar

2011
Oral glutamine attenuates cyclophosphamide-induced oxidative stress in the bladder but does not prevent hemorrhagic cystitis in rats.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cystitis; Disease Models, Animal; Glutamine; Hemorrhage; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar

2011
Influence of glutamine on morphological and functional changes of liver in the presence of extrahepatic biliary obstruction in rats.
    Acta cirurgica brasileira, 2010, Volume: 25, Issue:4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Ducts, Extrahepatic; Cholestasis, Extrahepatic; Disease Models, Animal; Enteral Nutrition; Glutamine; Hepatic Duct, Common; Liver; Male; Postoperative Complications; Rats; Rats, Wistar

2010
Lymph duct ligation during ischemia/reperfusion prevents pulmonary dysfunction in a rat model with ω-3 polyunsaturated fatty acid and glutamine.
    Nutrition (Burbank, Los Angeles County, Calif.), 2011, Volume: 27, Issue:5

    Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Endotoxins; Fatty Acids, Omega-3; Glutamine; Inflammation; Intestinal Diseases; Intestines; Ligation; Lipopolysaccharides; Lung Injury; Lymph Nodes; Lymphatic System; Male; Mesentery; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2011
The effects of oral liquid and intravenous glutamine on bowel adaptation in a rabbit short bowel syndrome model.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2010, Volume: 21, Issue:3

    Topics: Adaptation, Physiological; Administration, Oral; Animals; Disease Models, Animal; Dosage Forms; Glutamine; Injections, Intravenous; Male; Rabbits; Short Bowel Syndrome

2010
Protective mechanism of glutamine on the expression of proliferating cell nuclear antigen after cisplatin-induced intestinal mucosal injury.
    Pediatric surgery international, 2011, Volume: 27, Issue:2

    Topics: Animals; Cisplatin; Disease Models, Animal; DNA; Gene Expression; Glutamine; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction

2011
Chronic electrographic seizure reduces glutamine and elevates glutamate in the extracellular fluid of rat brain.
    Brain research, 2011, Jan-31, Volume: 1371

    Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Extracellular Fluid; Glutamic Acid; Glutamine; Hippocampus; Intracellular Fluid; Kainic Acid; Male; Microdialysis; Neurotoxins; Rats; Rats, Wistar; Synaptic Vesicles

2011
New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA.
    Journal of hepatology, 2011, Volume: 55, Issue:2

    Topics: Acyl Coenzyme A; Amino-Acid N-Acetyltransferase; Ammonia; Animals; Anticonvulsants; Citrulline; Disease Models, Animal; Glutamates; Glutamine; Humans; Hyperammonemia; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Models, Biological; Rats; Rats, Wistar; Urea; Valproic Acid

2011
Lateral superior olive function in congenital deafness.
    Hearing research, 2011, Volume: 277, Issue:1-2

    Topics: Animals; Auditory Pathways; Auditory Perception; Carrier Proteins; Cochlear Nerve; Deafness; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Excitatory Postsynaptic Potentials; Glutamine; Glycine; Immunohistochemistry; Membrane Proteins; Mice; Mice, Mutant Strains; Models, Neurological; Mutation; Neural Inhibition; Olivary Nucleus; Patch-Clamp Techniques; Time Factors

2011
GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium.
    Inflammatory bowel diseases, 2011, Volume: 17, Issue:11

    Topics: Adult; Animals; Biomarkers; Body Weight; Case-Control Studies; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Male; Metabolomics; Mice; Mice, Inbred C57BL; Middle Aged

2011
Early predictive biomarkers for lesion after transient cerebral ischemia.
    Stroke, 2011, Volume: 42, Issue:3

    Topics: Animals; Aspartic Acid; Biomarkers; Disease Models, Animal; Glutamine; Ischemic Attack, Transient; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Predictive Value of Tests; Taurine; Time Factors

2011
The effect of glutamine on oxidative damage in an experimental abdominal compartment syndrome model in rats.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2011, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Compartment Syndromes; Disease Models, Animal; Glutamine; Glutathione; Intestines; Liver; Lung; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Pressure; Rats; Rats, Wistar

2011
Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models.
    JPEN. Journal of parenteral and enteral nutrition, 2011, Volume: 35, Issue:2

    Topics: Animals; Area Under Curve; Caspase 3; Cell Survival; Colitis; Colon; Cytokines; Dextran Sulfate; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Glutamine; Heat-Shock Proteins; Hemorrhage; HSP70 Heat-Shock Proteins; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley

2011
Glutamine restores myocardial cytochrome C oxidase activity and improves cardiac function during experimental sepsis.
    JPEN. Journal of parenteral and enteral nutrition, 2011, Volume: 35, Issue:2

    Topics: Animals; Blood Pressure; Cardiovascular Agents; Disease Models, Animal; Electron Transport Complex IV; Glutamine; Heart; Heart Ventricles; Male; Muscle Contraction; Myocardium; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Sepsis

2011
Glutamine contributes to ameliorate inflammation after renal ischemia/reperfusion injury in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:5

    Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Glutamine; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Nephritis; Rats; Rats, Wistar; Reperfusion Injury

2011
A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses.
    Journal of biomolecular NMR, 2011, Volume: 49, Issue:3-4

    Topics: Animals; Cerebellum; Cerebral Cortex; Disease Models, Animal; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Mice; Neuronal Ceroid-Lipofuscinoses; Neurons; Pigments, Biological

2011
Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation under high-altitude hypoxic environment.
    World journal of gastroenterology, 2011, Mar-28, Volume: 17, Issue:12

    Topics: Altitude; Amine Oxidase (Copper-Containing); Animals; Apoptosis; Bacterial Translocation; Disease Models, Animal; Endotoxins; Glutamine; Hypoxia; In Situ Nick-End Labeling; Intestinal Diseases; Intestinal Mucosa; Intestines; Lymph Nodes; Male; Malondialdehyde; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spleen; Starvation; Superoxide Dismutase; Time Factors

2011
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
    Neuroscience, 2011, Jun-30, Volume: 185

    Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry

2011
p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.
    Gut, 2011, Volume: 60, Issue:11

    Topics: Ammonia; Animals; Blotting, Western; Cerebellum; Cerebral Cortex; Cognition; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Imidazoles; Immunohistochemistry; Learning; Male; MAP Kinase Signaling System; Microglia; Motor Activity; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Portacaval Shunt, Surgical; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Rats; Rats, Wistar

2011
Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration.
    The Journal of comparative neurology, 2011, Oct-01, Volume: 519, Issue:14

    Topics: Adult; Animals; Animals, Genetically Modified; Disease Models, Animal; Disease Progression; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Opsins; Rabbits; Retina; Retinal Degeneration; Retinitis Pigmentosa; Taurine

2011
Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G).
    Journal of neurochemistry, 2011, Volume: 118, Issue:5

    Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Color Therapy; Disease Models, Animal; Endopeptidase K; Glutamine; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Transgenic; Mutation; Oxidation-Reduction; Protein Binding; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc

2011
L-glutamine supplementation prevents myenteric neuron loss and has gliatrophic effects in the ileum of diabetic rats.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Glutamine; Ileum; Immunohistochemistry; Male; Microscopy, Confocal; Myenteric Plexus; Neuroglia; Neuroprotective Agents; Rats; Rats, Wistar; Treatment Outcome

2011
Simultaneously changes in striatum dopaminergic and glutamatergic parameters following hypoxic-ischemic neuronal injury in newborn piglets.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:3

    Topics: Animals; Animals, Newborn; Basal Ganglia; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Glutamine; Hypoxia-Ischemia, Brain; Immunohistochemistry; Magnetic Resonance Spectroscopy; Male; Neurons; Receptors, Dopamine D2; Swine

2012
Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2012, Volume: 13, Issue:6

    Topics: Animals; Choline; Depression; Disease Models, Animal; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Helplessness, Learned; Hippocampus; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Taurine

2012
NMR and pattern recognition can distinguish neuroinflammation and peripheral inflammation.
    Journal of proteome research, 2011, Oct-07, Volume: 10, Issue:10

    Topics: Animals; Citrates; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamine; Humans; Inflammation; Lactates; Magnetic Resonance Spectroscopy; Male; Models, Statistical; Multiple Sclerosis; Mycobacterium tuberculosis; Pattern Recognition, Automated; Pentanoic Acids; Rats; Rats, Inbred Lew; Reproducibility of Results

2011
Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis.
    Journal of hepatology, 2012, Volume: 56, Issue:1

    Topics: Amino Acids; Ammonia; Animals; Brain; Disease Models, Animal; Evoked Potentials, Motor; Glutamine; Hepatic Encephalopathy; Male; Ornithine; Phenylacetates; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley

2012
Endotoxemia affects citrulline, arginine and glutamine bioavailability.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Animals; Area Under Curve; Arginine; Biological Availability; Citrulline; Disease Models, Animal; Endotoxemia; Glutamine; Lipopolysaccharides; Male; Random Allocation; Rats; Rats, Sprague-Dawley

2012
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
    Biological psychiatry, 2012, Jun-01, Volume: 71, Issue:11

    Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia

2012
Effect of glutamine on the mRNA level of key enzymes of malate-aspartate shuttle in the rat intestine subjected to ischemia reperfusion.
    Acta cirurgica brasileira, 2011, Volume: 26 Suppl 1

    Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Dipeptides; Disease Models, Animal; Glutamine; Intestine, Small; Malate Dehydrogenase; Malates; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger; Time Factors

2011
Effects of dietary glutamine on inflammatory mediator gene expressions in rats with streptozotocin-induced diabetes.
    Nutrition (Burbank, Los Angeles County, Calif.), 2012, Volume: 28, Issue:3

    Topics: Animals; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Experimental; Dietary Supplements; Disease Models, Animal; Down-Regulation; Fructosamine; Gene Expression; Glutamine; Inflammation; Inflammation Mediators; Interleukin-17; Interleukin-23; Interleukin-6; Leukocytes, Mononuclear; Male; Niacinamide; Rats; Rats, Wistar; RNA, Messenger; Th17 Cells; Transforming Growth Factor beta1

2012
Arginyl-glutamine dipeptide or docosahexaenoic acid attenuates hyperoxia-induced small intestinal injury in neonatal mice.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 54, Issue:4

    Topics: Animals; Animals, Newborn; Apoptosis; Arginine; Dietary Supplements; Dipeptides; Disease Models, Animal; Docosahexaenoic Acids; Female; Glutamine; Hyperoxia; Intestinal Mucosa; Intestine, Small; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Peroxidase

2012
Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol.
    Hepatology (Baltimore, Md.), 2012, Volume: 55, Issue:4

    Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Cell Lineage; Cell Transplantation; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Glutamine; Hepatocyte Growth Factor; Hepatocytes; Humans; In Vitro Techniques; Liver Failure; Mice; Mice, SCID; Oncostatin M; Pluripotent Stem Cells; Treatment Outcome

2012
Glutamine prevents intestinal mucosal injury induced by cyclophosphamide in rats.
    Pediatric surgery international, 2012, Volume: 28, Issue:3

    Topics: Administration, Oral; Animals; Apoptosis; Cell Proliferation; Cyclophosphamide; Disease Models, Animal; Enterocytes; Glutamine; Ileal Diseases; Ileum; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Rats; Rats, Wistar; Treatment Outcome

2012
Gu-4 suppresses affinity and avidity modulation of CD11b and improves the outcome of mice with endotoxemia and sepsis.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Animals; CD11b Antigen; Cell Adhesion; Disease Models, Animal; Endotoxemia; Glutamine; Lactose; Leukocytes; Lymphocyte Activation; Mice; Microcirculation; Sepsis; Survival Rate

2012
Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Cell Survival; Disease Models, Animal; DNA Damage; Gene Expression; Glutamate-Ammonia Ligase; Glutamine; Hippocampus; Humans; Hydrogen Peroxide; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Stress, Physiological

2012
Effects of enteral and parenteral glutamine on intestinal mucosa and on levels of blood glutamine, tumor necrosis factor-alpha, and interleukin-10 in an experimental sepsis model.
    Saudi medical journal, 2012, Volume: 33, Issue:3

    Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glutamine; Injections, Intraperitoneal; Interleukin-1; Intestinal Mucosa; Rats; Rats, Wistar; Sepsis; Tumor Necrosis Factor-alpha

2012
Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
    Nature, 2012, Mar-28, Volume: 483, Issue:7391

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Respiration; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Doxycycline; Electron Transport; Gene Expression Regulation, Neoplastic; Genes, myc; Glutamine; Homeostasis; Humans; Liver Neoplasms; Mechanistic Target of Rapamycin Complex 1; Mice; Mitochondria; Multiprotein Complexes; Oncogene Protein p55(v-myc); Protein Biosynthesis; Protein Kinases; Proteins; Repressor Proteins; RNA Interference; Signal Transduction; TOR Serine-Threonine Kinases

2012
Glutamine preconditioning protects against local and systemic injury induced by orthopaedic surgery.
    The journal of nutrition, health & aging, 2012, Volume: 16, Issue:4

    Topics: Animals; Bronchoalveolar Lavage; Disease Models, Animal; Femoral Fractures; Glutamine; Ischemic Preconditioning; Male; Muscle, Skeletal; Orthopedic Procedures; Protective Agents; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2012
Neuroprotective effects of angiotensin II type 1 receptor (AT1-R) blocker via modulating AT1-R signaling and decreased extracellular glutamate levels.
    Investigative ophthalmology & visual science, 2012, Jun-26, Volume: 53, Issue:7

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Survival; Disease Models, Animal; Electroretinography; Extracellular Fluid; Gene Expression Regulation; Glutamine; Immunohistochemistry; Male; NADPH Oxidases; Phosphoproteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reperfusion Injury; Retina; Retinal Diseases; Retinal Ganglion Cells; RNA, Messenger; Signal Transduction; Tetrazoles; Vitreous Body

2012
Therapeutic effects of lactosyl derivative Gu-4 in a collagen-induced arthritis rat model.
    Glycoconjugate journal, 2012, Volume: 29, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cattle; Cell Proliferation; Cells, Cultured; Collagen Type II; Disease Models, Animal; Drug Administration Schedule; Edema; Etanercept; Female; Glutamine; Humans; Immunoglobulin G; Joints; Lactose; Lymphocytes; Organ Size; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Rheumatoid Factor

2012
[Impact of glutamine and ω-3 polyunsaturated fatty acids on intestinal permeability and lung cell apoptosis during intestinal ischemia-reperfusion injury in a rat model].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2012, Volume: 15, Issue:5

    Topics: Animals; Apoptosis; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Intestines; Ligation; Lung; Lymphatic Vessels; Male; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2012
Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
    The European journal of neuroscience, 2012, Volume: 36, Issue:6

    Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Dependovirus; Disease Models, Animal; Female; Genetic Vectors; Glutamine; Huntingtin Protein; Huntington Disease; Hypothalamus; Inclusion Bodies; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Mutation; Nerve Tissue Proteins; Neuropeptides; Nuclear Proteins; Orexins; Prosencephalon; Rats; Rats, Sprague-Dawley

2012
Protective effects of glutamine in a rat model of endotoxemia.
    Molecular medicine reports, 2012, Volume: 6, Issue:4

    Topics: Animals; Apoptosis; Brain; Disease Models, Animal; Endotoxemia; Female; Glutamine; HSP70 Heat-Shock Proteins; Lipopolysaccharides; Male; Neurons; Neuroprotective Agents; NF-kappa B; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Up-Regulation

2012
Modulation of the nuclear factor-kappa B (NF-κB) signalling pathway by glutamine in peritoneal macrophages of a murine model of protein malnutrition.
    European journal of nutrition, 2013, Volume: 52, Issue:4

    Topics: Animals; Animals, Outbred Strains; Cells, Cultured; Corticosterone; Dietary Supplements; Disease Models, Animal; Down-Regulation; Glutamine; Immunomodulation; Interleukin-1alpha; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Protein-Energy Malnutrition; Signal Transduction

2013
Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis.
    World journal of gastroenterology, 2012, Aug-28, Volume: 18, Issue:32

    Topics: Administration, Rectal; Animals; Apoptosis; Butyrates; Colitis; Colon; Colostomy; Cytokines; Disease Models, Animal; Endoscopy, Gastrointestinal; Enema; Female; Fibrosis; Glutamine; Inflammation; Intestinal Mucosa; Male; Rats; Rats, Wistar

2012
Effects of glutamine treatment on myocardial damage and cardiac function in rats after severe burn injury.
    International journal of clinical and experimental pathology, 2012, Volume: 5, Issue:7

    Topics: Adenosine Triphosphate; Administration, Oral; Animals; Aspartate Aminotransferases; Biomarkers; Burns; Creatine Kinase, MB Form; Disease Models, Animal; Edema, Cardiac; Glutamine; Glutathione; Heart; Heart Diseases; Heart Function Tests; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Protective Agents; Rats; Rats, Wistar; Water

2012
Disrupted-in-schizophrenia-1 Gln31Leu polymorphism results in social anhedonia associated with monoaminergic imbalance and reduction of CREB and β-arrestin-1,2 in the nucleus accumbens in a mouse model of depression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:3

    Topics: Anhedonia; Animals; Antidepressive Agents; Arrestins; beta-Arrestin 1; beta-Arrestins; Biogenic Monoamines; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Glutamine; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nucleus Accumbens; Polymorphism, Genetic; Signal Transduction

2013
Glutamine suppresses DNFB-induced contact dermatitis by deactivating p38 mitogen-activated protein kinase via induction of MAPK phosphatase-1.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:3

    Topics: Animals; Butadienes; Cell Line; Cells, Cultured; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Female; Glutamine; Humans; Keratinocytes; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Small Interfering

2013
Effects of glutamine supplementation on muscle function and stress responses in a mouse model of spinal cord injury.
    Experimental physiology, 2013, Volume: 98, Issue:3

    Topics: Animals; Disease Models, Animal; Glutamine; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Muscle, Skeletal; Myofibrils; Neoplasm Proteins; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2013
Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice.
    Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:3

    Topics: Animals; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Dietary Fiber; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Interleukin-1beta; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Oligosaccharides; RNA, Messenger

2013
Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Apr-01, Volume: 304, Issue:7

    Topics: Animals; Disease Models, Animal; Gastrointestinal Tract; Glutamine; Graft vs Host Disease; Jejunum; Lymphocyte Transfusion; Mice; Occludin; Permeability; Tumor Necrosis Factor-alpha

2013
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation.
    Brain : a journal of neurology, 2002, Volume: 125, Issue:Pt 8

    Topics: Aging; Animals; Biological Transport; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microdialysis; Mutation; Nerve Tissue Proteins; Nuclear Proteins

2002
The conserved glutamine-rich region of chick csal1 and csal3 mediates protein interactions with other spalt family members. Implications for Townes-Brocks syndrome.
    The Journal of biological chemistry, 2003, Feb-21, Volume: 278, Issue:8

    Topics: Amino Acid Sequence; Animals; Cell Line; Chick Embryo; Conserved Sequence; Disease Models, Animal; Extremities; Glutamine; Homeodomain Proteins; Humans; Molecular Sequence Data; Morphogenesis; Peptide Fragments; Protein Isoforms; Recombinant Proteins; Syndrome; Transcription Factors; Transfection; Xenopus Proteins; Zinc Fingers

2003
Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus.
    Journal of neurochemistry, 2003, Volume: 85, Issue:1

    Topics: Acetates; Animals; Astrocytes; Biomarkers; Brain Stem; Carbon Isotopes; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Hydrocephalus; Kaolin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Taurine; Telencephalon

2003
Role of manganese accumulation in increased brain glutamine of the cirrhotic rat.
    Neurochemical research, 2003, Volume: 28, Issue:6

    Topics: Animals; Brain; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Cirrhosis, Experimental; Male; Manganese; Organ Specificity; Rats; Rats, Wistar; Time Factors

2003
Nutritional benefits of enteral alanyl-glutamine supplementation on rat small intestinal damage induced by cyclophosphamide.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:6

    Topics: Alanine; Amino Acid Transport Systems; Animals; Antineoplastic Agents, Alkylating; Biomarkers; Body Weight; Cadherins; Carrier Proteins; Cyclophosphamide; Dietary Supplements; Dipeptides; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

2003
The effect of immunonutrition on bacterial translocation, and intestinal villus atrophy in experimental obstructive jaundice.
    Clinical nutrition (Edinburgh, Scotland), 2003, Volume: 22, Issue:3

    Topics: Animals; Arginine; Atrophy; Bacterial Translocation; Cholestasis, Extrahepatic; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Intestinal Mucosa; Liver; Lymph Nodes; Male; Mesentery; Nutritional Physiological Phenomena; Random Allocation; Rats; Rats, Wistar; RNA; Spleen

2003
Cellular energetics in hemorrhagic shock: restoring adenosine triphosphate to the cells.
    The Journal of trauma, 2003, Volume: 54, Issue:5 Suppl

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Antioxidants; Apoptosis; Carotenoids; Disease Models, Animal; Energy Metabolism; Fluid Therapy; Glutamine; Intestine, Small; Liver; Male; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Vitamin A

2003
Obstructive jaundice alters proliferating cell nuclear antigen expression in rat small intestine.
    World journal of surgery, 2003, Volume: 27, Issue:10

    Topics: Animals; Common Bile Duct; Disease Models, Animal; Glutamine; Intestinal Mucosa; Intestine, Small; Jaundice, Obstructive; Ligation; Male; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors

2003
The role of dietary supplementation with L-glutamine in inflammatory mediator release and intestinal injury in hypoxia/reoxygenation-induced experimental necrotizing enterocolitis.
    Annals of nutrition & metabolism, 2003, Volume: 47, Issue:6

    Topics: Administration, Oral; Animals; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocolitis, Necrotizing; Glutamine; Hypoxia; Intestinal Mucosa; Intestines; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Random Allocation; Tumor Necrosis Factor-alpha

2003
Effects of dietary glutamine on antioxidant enzyme activity and immune response in burned mice.
    Nutrition (Burbank, Los Angeles County, Calif.), 2003, Volume: 19, Issue:10

    Topics: Animals; Antibody Formation; Antioxidants; Bacterial Vaccines; Burns; Diet; Disease Models, Animal; Glutamine; Male; Mice; Mice, Inbred BALB C; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Survival Analysis

2003
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured

2003
Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
    Human molecular genetics, 2004, Jan-01, Volume: 13, Issue:1

    Topics: Animals; Ataxin-7; beta-Galactosidase; Blotting, Western; Cell Nucleus; Cells, Cultured; Disease Models, Animal; DNA Primers; Gene Expression Regulation; Genetic Vectors; Glutamine; Homeodomain Proteins; Immunohistochemistry; Luciferases; Mice; Mutagenesis; Nerve Tissue Proteins; Photoreceptor Cells, Vertebrate; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retinal Degeneration; Spinocerebellar Ataxias; Trans-Activators; Transcription, Genetic; Two-Hybrid System Techniques

2004
Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3.
    Physiological genomics, 2004, Feb-13, Volume: 16, Issue:3

    Topics: Animals; Ataxin-3; Brain; Cerebellum; Choline; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamine; Glycogen; Humans; Lactic Acid; Machado-Joseph Disease; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Phosphorylcholine; Repressor Proteins; Telencephalon; Transcription Factors; Trinucleotide Repeat Expansion

2004
Impaired energy metabolism during neonatal sepsis: the effects of glutamine.
    The Proceedings of the Nutrition Society, 2003, Volume: 62, Issue:3

    Topics: Animals; Animals, Suckling; Basal Metabolism; Disease Models, Animal; Endotoxemia; Energy Metabolism; Glutamine; Humans; Infant, Newborn; Rats; Sepsis; Thermogenesis

2003
Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding.
    Brain research, 2004, Jan-23, Volume: 996, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Dopamine; Female; Fetus; Glutamine; Male; Neural Inhibition; Pregnancy; Prenatal Nutritional Physiological Phenomena; Protein Deficiency; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Sex Factors; Time Factors

2004
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia.
    Brain research, 2004, Feb-27, Volume: 999, Issue:1

    Topics: Animals; Brain Edema; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hypothermia, Induced; Inositol; Intracranial Hypertension; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Taurine

2004
Glutamatergic regulation of long-term grafts of fetal lateral ganglionic eminence in a rat model of Huntington's disease.
    Neurobiology of disease, 2004, Volume: 15, Issue:3

    Topics: Animals; Brain Injuries; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Fetal Tissue Transplantation; Fluorescent Antibody Technique; Glutamine; Haloperidol; Huntington Disease; Immunohistochemistry; Male; Neurons, Afferent; Proto-Oncogene Proteins c-fos; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate

2004
Effect of glutamine and bile acid on hepatocyte apoptosis after bile duct ligation in the rat.
    World journal of surgery, 2004, Volume: 28, Issue:5

    Topics: Administration, Oral; Animals; Apoptosis; Cholestasis, Extrahepatic; Common Bile Duct; Deoxycholic Acid; Disease Models, Animal; Glutamine; Hepatocytes; Ligation; Male; Random Allocation; Rats; Rats, Sprague-Dawley

2004
Evolution of expression of cardiac phenotypes over a 4-year period in the beta-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy.
    Journal of molecular and cellular cardiology, 2004, Volume: 36, Issue:5

    Topics: Adenosine Triphosphatases; Aging; Animals; Animals, Genetically Modified; Calcium; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Echocardiography; Glutamine; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myofibrils; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Phenotype; Rabbits; Signal Transduction; Time Factors; Transgenes

2004
Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose.
    Neurotoxicology, 2004, Volume: 25, Issue:4

    Topics: Animals; Blood Glucose; Brain; Carbon Isotopes; Disease Models, Animal; Energy Metabolism; gamma-Aminobutyric Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Manganese; Manganese Poisoning; Rats; Rats, Sprague-Dawley

2004
Effects of protein deprivation on growth and small intestine morphology are not improved by glutamine or glutamate in gastrostomy-fed rat pups.
    Journal of pediatric gastroenterology and nutrition, 2004, Volume: 39, Issue:1

    Topics: Alkaline Phosphatase; alpha-Glucosidases; Animals; Animals, Newborn; Claudin-1; Dietary Proteins; Disease Models, Animal; Gastrostomy; Glutamic Acid; Glutamine; Immunoblotting; Intestinal Mucosa; Intestine, Small; Membrane Proteins; Occludin; Random Allocation; Rats; Rats, Sprague-Dawley; Tight Junctions; Weight Gain

2004
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.
    Nature medicine, 2004, Volume: 10, Issue:8

    Topics: Adenoviridae; Animals; Ataxin-1; Ataxins; Blotting, Northern; Brain; Cells, Cultured; Disease Models, Animal; Gene Expression; Glutamine; Immunohistochemistry; Mice; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Plasmids; Psychomotor Performance; Purkinje Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spinocerebellar Ataxias; Transduction, Genetic

2004
Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency.
    Neurobiology of disease, 2004, Volume: 16, Issue:3

    Topics: Aldehyde Oxidoreductases; Amino Acids; Animals; Brain; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Succinate-Semialdehyde Dehydrogenase

2004
RNAi quashes polyQ.
    Nature medicine, 2004, Volume: 10, Issue:8

    Topics: Adenoviridae; Animals; Ataxin-1; Ataxins; Brain; Disease Models, Animal; Genetic Vectors; Glutamine; Humans; Mice; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Purkinje Cells; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spinocerebellar Ataxias

2004
In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death.
    Hippocampus, 2004, Volume: 14, Issue:5

    Topics: Animals; Apoptosis; Brain; Brain Injuries; Cell Death; Cell Survival; Denervation; Disease Models, Animal; Energy Metabolism; Fornix, Brain; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hippocampus; L-Lactate Dehydrogenase; Lactic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley

2004
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
    Nature neuroscience, 2004, Volume: 7, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Blood Vessels; Blotting, Western; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; Encephalitis; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Glutamine; Humans; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron; Middle Aged; Mutation; Peptide Fragments; Pia Mater; Postmortem Changes; Thy-1 Antigens

2004
Arginine and glutamine availability and macrophage functions in the obese insulin-resistant Zucker rat.
    Journal of cellular physiology, 2005, Volume: 202, Issue:1

    Topics: Animals; Arginine; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Genetic Predisposition to Disease; Glutamine; Immune System; Immunity, Innate; Infections; Insulin Resistance; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; Obesity; Rats; Rats, Zucker; Signal Transduction; Tumor Necrosis Factor-alpha

2005
Absorption of enterally administered N-acetyl-l-glutamine versus glutamine in pigs.
    Clinical nutrition (Edinburgh, Scotland), 2004, Volume: 23, Issue:6

    Topics: Animals; Biological Availability; Digestion; Disease Models, Animal; Enteral Nutrition; Glucose; Glutamine; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Swine

2004
Prophylactic administration of topical glutamine enhances the capability of the rat colon to resist inflammatory damage.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:10

    Topics: Adenosine Triphosphate; Administration, Topical; Animals; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Female; Glutamine; Glutathione; Guanosine Triphosphate; Intestinal Mucosa; Malondialdehyde; Mitotic Index; Rats; Rats, Inbred Strains

2004
Cerebral glutamate metabolism in Parkinson's disease: an in vivo dynamic (13)C NMS study in the rat.
    Experimental neurology, 2005, Volume: 191, Issue:2

    Topics: Animals; Antiparkinson Agents; Basal Ganglia; Carbon Isotopes; Disease Models, Animal; Dopamine; Glutamic Acid; Glutaminase; Glutamine; Infusions, Intravenous; Levodopa; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Sodium Acetate

2005
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
    Journal of neurochemistry, 2005, Volume: 92, Issue:6

    Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation

2005
Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion.
    The Journal of trauma, 2005, Volume: 58, Issue:3

    Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Electrophoretic Mobility Shift Assay; Enteral Nutrition; Glutamine; Immunity, Mucosal; Immunologic Factors; Inflammation; Jejunum; Male; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Patient Selection; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Risk Factors; Time Factors; Transcription Factor AP-1

2005
[Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons].
    Medecine sciences : M/S, 2005, Volume: 21, Issue:5

    Topics: Animals; Disease Models, Animal; Glutamine; Huntington Disease; Mammals; Mutation; Nematoda; Peptides; Resveratrol; Sirtuins; Stilbenes

2005
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
    Neurochemistry international, 2005, Volume: 47, Issue:1-2

    Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes; Choline; Disease Models, Animal; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Lupus Erythematosus, Systemic; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Protons; Up-Regulation

2005
Lack of cardioprotection from metabolic support with glutamine or glutamate in a porcine coronary occlusion model.
    Scandinavian cardiovascular journal : SCJ, 2005, Volume: 39, Issue:1-2

    Topics: Analysis of Variance; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Female; Glutamic Acid; Glutamine; Hemodynamics; Infusions, Intravenous; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Probability; Random Allocation; Reference Values; Risk Factors; Sensitivity and Specificity; Swine; Tomography, Emission-Computed, Single-Photon; Vascular Patency

2005
Effect of oral glutamine administration on bacterial tanslocation, endotoxemia, liver and ileal morphology, and apoptosis in rats with obstructive jaundice.
    World journal of surgery, 2005, Volume: 29, Issue:10

    Topics: Administration, Oral; Animals; Apoptosis; Bacterial Translocation; Disease Models, Animal; Endotoxemia; Gastrointestinal Agents; Glutamine; Ileum; Jaundice, Obstructive; Liver; Male; Rats; Rats, Wistar

2005
[Effect of ecoimmunonutrition on gut barrier function in rats with systemic inflammatory response syndrome].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2005, Volume: 8, Issue:2

    Topics: Animals; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Mucosa; Lactulose; Male; Rats; Rats, Sprague-Dawley; Systemic Inflammatory Response Syndrome

2005
Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?
    Molecular vision, 2005, Sep-01, Volume: 11

    Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glutamic Acid; Glutamine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Confocal; Neuroprotective Agents; Organ Culture Techniques; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury.
    Journal of neurotrauma, 2005, Volume: 22, Issue:10

    Topics: Animals; Brain Injuries; Citric Acid Cycle; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Pentose Phosphate Pathway; Rats; Up-Regulation

2005
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: Aging; Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Knockout; Models, Biological; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neurotransmitter Agents; Phenotype; Spectrophotometry; Time Factors

2005
Bcl-2 and Mn-SOD antisense oligodeoxynucleotides and a glutamine-enriched diet facilitate elimination of highly resistant B16 melanoma cells by tumor necrosis factor-alpha and chemotherapy.
    The Journal of biological chemistry, 2006, Jan-06, Volume: 281, Issue:1

    Topics: Animal Feed; Animals; Antineoplastic Agents; Combined Modality Therapy; Disease Models, Animal; Drug Resistance, Neoplasm; Genetic Therapy; Glutamine; Glutathione; Male; Melanoma; Mice; Mice, Inbred C57BL; Mitochondria; Neoplasm Transplantation; Oligonucleotides, Antisense; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Soft Tissue Neoplasms; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2006
Intrinsic gluconeogenesis is enhanced in renal proximal tubules of Zucker diabetic fatty rats.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructose-Bisphosphatase; Gluconeogenesis; Glucose-6-Phosphatase; Glutamine; Glycerol; Kidney Tubules, Proximal; Lactic Acid; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Tissue Culture Techniques

2006
Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models.
    Nature neuroscience, 2006, Volume: 9, Issue:2

    Topics: Animals; Calcium Channels, L-Type; Corpus Striatum; Dendritic Spines; Disease Models, Animal; Glutamine; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Neural Pathways; Organ Culture Techniques; Parkinson Disease; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; Synapses

2006
Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Glutamine; HSP70 Heat-Shock Proteins; Injections, Intraperitoneal; Ischemia; Liver; Male; Necrosis; Neutrophils; Premedication; Protective Agents; Rats; Rats, Zucker; Reperfusion Injury; Survival Rate; Time Factors; Up-Regulation

2006
Progressive disruption of cellular protein folding in models of polyglutamine diseases.
    Science (New York, N.Y.), 2006, Mar-10, Volume: 311, Issue:5766

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dynamin I; Glutamine; Humans; Mutation; Neurodegenerative Diseases; Peptides; Protein Folding; Temperature; Tropomyosin

2006
Prevention of bacterial translocation using glutamine: a new strategy of investigation.
    Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:4

    Topics: Animals; Bacterial Translocation; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Glutamine; Intestinal Obstruction; Male; Random Allocation; Rats; Rats, Wistar

2006
BIOMEDICINE: One Misfolded Protein Allows Others to Sneak By.
    Science (New York, N.Y.), 2006, Mar-10, Volume: 311, Issue:5766

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Glutamine; Humans; Huntington Disease; Mutation; Neurodegenerative Diseases; Peptides; Protein Conformation; Protein Folding; Temperature

2006
Essential role of pepsin in pathogenesis of acid reflux esophagitis in rats.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Glutamine; Male; Pepsin A; Pepstatins; Protease Inhibitors; Rats; Rats, Sprague-Dawley

2006
Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia.
    Shock (Augusta, Ga.), 2006, Volume: 25, Issue:3

    Topics: Administration, Oral; Animals; Disease Models, Animal; DNA-Binding Proteins; Fever; Glutamine; Heat Shock Transcription Factors; Heat Stroke; HSP70 Heat-Shock Proteins; Humans; Intestinal Mucosa; Permeability; Rats; Survival Analysis; Transcription Factors

2006
Glutamine inhibits lipopolysaccharide-induced cytoplasmic phospholipase A2 activation and protects against endotoxin shock in mouse.
    Shock (Augusta, Ga.), 2006, Volume: 25, Issue:3

    Topics: Animals; Death; Disease Models, Animal; Endotoxins; Glutamine; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Phospholipases A; Phospholipases A2; Shock, Septic; Tumor Necrosis Factor-alpha

2006
The metabolism of C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats.
    Journal of neurochemistry, 2006, Volume: 97, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Infarction; Brain Ischemia; Carbon Radioisotopes; Cell Communication; Cell Death; Disease Models, Animal; Down-Regulation; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Infarction, Middle Cerebral Artery; Male; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2006
Influence of glutamine on pancreatic blood flow and apoptosis of pancreatic acinar in rats with severe acute pancreatitis.
    Chinese journal of digestive diseases, 2006, Volume: 7, Issue:2

    Topics: Animals; Apoptosis; Disease Models, Animal; Glutamine; In Situ Nick-End Labeling; Mesenteric Artery, Superior; Pancreas; Pancreatitis, Acute Necrotizing; Portal Vein; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Severity of Illness Index; Splanchnic Circulation; Splenic Artery; Ultrasonography

2006
The effect of glutamine on locomotor performance and skeletal muscle myosins following spinal cord injury in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 101, Issue:4

    Topics: Animals; Disease Models, Animal; Exploratory Behavior; Foot; Glutamine; Laminectomy; Male; Motor Activity; Muscle, Skeletal; Myosin Heavy Chains; Protein Isoforms; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries

2006
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
    Thrombosis research, 2007, Volume: 119, Issue:6

    Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Disease Models, Animal; Factor V; Ferric Compounds; Gene Frequency; Glutamine; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Thrombosis; Venous Thrombosis

2007
Arginine-enriched diet limits plasma and muscle glutamine depletion in head-injured rats.
    Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:10

    Topics: Animals; Arginine; Craniocerebral Trauma; Disease Models, Animal; Enteral Nutrition; Glutamine; Male; Muscle, Skeletal; Nutritional Requirements; Random Allocation; Rats; Rats, Sprague-Dawley

2006
Neuronal atrophy and synaptic alteration in a mouse model of dentatorubral-pallidoluysian atrophy.
    Brain : a journal of neurology, 2006, Volume: 129, Issue:Pt 9

    Topics: Animals; Atrophy; Axons; Cerebral Cortex; Corpus Callosum; Dendrites; Dendritic Spines; Disease Models, Animal; Glutamine; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Electron; Microtubules; Neurons; Peptides; Pyramidal Tracts; Spinocerebellar Degenerations; Synapses

2006
Modulation of p53 and c-myc in DMBA-induced mammary tumors by oral glutamine.
    Nutrition and cancer, 2006, Volume: 54, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glutamine; Glutathione; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53

2006
Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine.
    Neuro-degenerative diseases, 2004, Volume: 1, Issue:1

    Topics: Adenosine; Adrenergic Agents; Alzheimer Disease; Amphetamine; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamine; Injections, Intraventricular; Male; Mice; Motor Activity; Psychotic Disorders

2004
Brain metabolic markers reflect susceptibility status in cytokine gene knockout mice with murine cerebral malaria.
    International journal for parasitology, 2006, Volume: 36, Issue:13

    Topics: Animals; Brain; Cytokines; Disease Models, Animal; Disease Progression; Disease Susceptibility; Glucose; Glutamine; Magnetic Resonance Spectroscopy; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Mice, Knockout

2006
[Effects of glutamine given through different avenues on intestine mucosal barrier function in burned rats].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2006, Volume: 18, Issue:10

    Topics: Animals; Burns; Disease Models, Animal; Enteral Nutrition; Female; Glutamine; Intestinal Mucosa; Male; Parenteral Nutrition; Permeability; Random Allocation; Rats; Rats, Wistar

2006
Protection elicited by two glutamine auxotrophs of Mycobacterium tuberculosis and in vivo growth phenotypes of the four unique glutamine synthetase mutants in a murine model.
    Infection and immunity, 2006, Volume: 74, Issue:11

    Topics: Animals; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Mutation; Mycobacterium tuberculosis; Phenotype; Tuberculosis, Pulmonary

2006
Accumulation of 99mTc-Cysteine in experimental inflammatory lesions in comparison to 99mTc-glutamine and 99mTc-HIG.
    Nuklearmedizin. Nuclear medicine, 1997, Volume: 36, Issue:8

    Topics: Animals; Arthritis, Experimental; Cysteine; Disease Models, Animal; Glutamine; Immunoglobulins; Inflammation; Knee Joint; Mice; Organotechnetium Compounds; Radionuclide Imaging; Technetium

1997
Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy.
    Neurobiology of disease, 2007, Volume: 25, Issue:2

    Topics: Action Potentials; Amino Acid Transport System A; Amino Acid Transport Systems; Animals; beta-Alanine; Brain Injuries; Cerebral Cortex; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy, Post-Traumatic; Evoked Potentials; Glutamic Acid; Glutamine; Organ Culture Techniques; Rats

2007
Low intestinal glutamine level and low glutaminase activity in Crohn's disease: a rational for glutamine supplementation?
    Digestive diseases and sciences, 2006, Volume: 51, Issue:12

    Topics: Adult; Animals; Case-Control Studies; Colon; Crohn Disease; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Female; Glutaminase; Glutamine; Glutathione; Humans; Ileitis; Ileum; Indomethacin; Intestinal Mucosa; Lipid Peroxidation; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Rectus Abdominis

2006
[Effects of glutamine on matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-3 expressions in myocardium of rats with sepsis].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2006, Volume: 44, Issue:8

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Glutamine; Immunohistochemistry; In Situ Hybridization; Lipopolysaccharides; Male; Matrix Metalloproteinase 3; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sepsis; Time Factors; Tissue Inhibitor of Metalloproteinase-3

2006
Metformin therapy in a transgenic mouse model of Huntington's disease.
    Neuroscience letters, 2007, Jan-10, Volume: 411, Issue:2

    Topics: Age Factors; AMP-Activated Protein Kinases; Animals; Behavior, Animal; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glutamine; Huntington Disease; Hypoglycemic Agents; Male; Metformin; Mice; Mice, Transgenic; Motor Activity; Multienzyme Complexes; Protein Serine-Threonine Kinases; Sex Factors; Trinucleotide Repeats

2007
Glutamine alone or combined with short-chain fatty acids fails to enhance gut adaptation after massive enterectomy in rats.
    Acta cirurgica brasileira, 2006, Volume: 21 Suppl 4

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fatty Acids, Volatile; Glutamine; Intestinal Mucosa; Intestine, Small; Male; Random Allocation; Rats; Rats, Wistar; Short Bowel Syndrome

2006
Intestinal intraluminal injection of glutamine increases trolox total equivalent antioxidant capacity (TEAC) in hepatic ischemia-reperfusion.
    Acta cirurgica brasileira, 2006, Volume: 21 Suppl 4

    Topics: Animals; Antioxidants; Chromans; Disease Models, Animal; Glutamine; Intestine, Small; Liver; Male; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury

2006
Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia.
    Journal of neuroscience research, 2007, Nov-15, Volume: 85, Issue:15

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Dopamine; Energy Metabolism; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neurons; Schizophrenia; Synaptic Vesicles

2007
A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Mar-07, Volume: 27, Issue:10

    Topics: Animals; Animals, Genetically Modified; Ataxin-7; Cell Death; Cells, Cultured; Disease Models, Animal; Drosophila; Dyskinesias; Glutamine; Humans; Intranuclear Inclusion Bodies; Longevity; Male; Mutation; Nerve Tissue Proteins; Neurons; Peptides; Phenotype; Rats; Spinocerebellar Ataxias; Threonine

2007
Metabolic progression markers of neurodegeneration in the transgenic G93A-SOD1 mouse model of amyotrophic lateral sclerosis.
    The European journal of neuroscience, 2007, Volume: 25, Issue:6

    Topics: Age Factors; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Aspartic Acid; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Superoxide Dismutase; Time Factors

2007
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:5

    Topics: Amino Acid Substitution; Animals; Arginine; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Genetic Diseases, Inborn; Glutamine; Humans; Immune Tolerance; Immunologic Deficiency Syndromes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Mutagenesis, Site-Directed

2007
Does concomitant glucose and glutamine supplementation change the response of glutamine synthetase to fasting in healthy adult rats?
    Clinical nutrition (Edinburgh, Scotland), 2007, Volume: 26, Issue:5

    Topics: Animals; Dietary Supplements; Disease Models, Animal; Drug Synergism; Fasting; Female; Glucose; Glutamate-Ammonia Ligase; Glutamine; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Up-Regulation

2007
Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat.
    Toxicology, 2007, Jul-17, Volume: 236, Issue:3

    Topics: Acetic Acid; Animals; Biomarkers; Colitis; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Glutamine; Glutathione Peroxidase; Immunologic Factors; Male; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar

2007
Effects of glutamine supplementation on gut barrier, glutathione content and acute phase response in malnourished rats during inflammatory shock.
    World journal of gastroenterology, 2007, May-28, Volume: 13, Issue:20

    Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Bacterial Translocation; Blood Proteins; Dietary Supplements; Disease Models, Animal; Glutamine; Glutathione; Glycoproteins; Inflammatory Bowel Diseases; Intestinal Mucosa; Irritants; Liver; Male; Malnutrition; Orosomucoid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Turpentine

2007
The effect of L-glutamine on mucosal healing in experimental colitis is superior to short-chain fatty acids.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2007, Volume: 18, Issue:2

    Topics: Acids, Acyclic; Administration, Oral; Animals; Colitis; Disease Models, Animal; DNA; Enema; Glutamine; Intestinal Mucosa; Rats; Rats, Wistar; Regeneration; Wound Healing

2007
Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:6

    Topics: Ammonia; Animals; Brain Chemistry; Disease Models, Animal; Extracellular Space; Female; Glutamic Acid; Glutamine; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Sorption Detoxification; Swine

2007
Astrocytes may play a role in the etiology of absence epilepsy: a comparison between immature GAERS not yet expressing seizures and adults.
    Neurobiology of disease, 2007, Volume: 28, Issue:2

    Topics: Acetic Acid; Aging; Animals; Astrocytes; Brain; Cell Communication; Cell Differentiation; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Absence; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamine; Magnetic Resonance Spectroscopy; Male; Mitochondria; Neural Inhibition; Neurons; Rats; Up-Regulation

2007
Changes in the rates of the tricarboxylic acid (TCA) cycle and glutamine synthesis in the monkey brain with hemiparkinsonism induced by intracarotid infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): studies by non-invasive 13C-magnetic reso
    Brain research, 2007, Nov-21, Volume: 1181

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Brain; Carbon Isotopes; Citric Acid Cycle; Disease Models, Animal; Dopamine; Female; Glutamine; Macaca fascicularis; Magnetic Resonance Spectroscopy; Parkinsonian Disorders

2007
Effect of glutamine on gut glutathione fractional release in the implanted tumor model.
    Nutrition and cancer, 2007, Volume: 59, Issue:2

    Topics: Amino Acids; Animals; Antioxidants; Disease Models, Animal; Electrolytes; Female; Glucose; Glutamine; Glutathione; Intestinal Mucosa; Intestines; Mammary Neoplasms, Experimental; Nutritional Status; Parenteral Nutrition Solutions; Random Allocation; Rats; Rats, Inbred F344; Solutions

2007
Glutamine improves myocardial function following ischemia-reperfusion injury.
    Asian cardiovascular & thoracic annals, 2007, Volume: 15, Issue:6

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Disease Models, Animal; Drug Administration Schedule; Glutamine; Hemodynamics; Injections, Intraperitoneal; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley

2007
Cerebral blood flow autoregulation in experimental liver failure.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:5

    Topics: Ammonia; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Glutamic Acid; Glutamine; Homeostasis; Intracranial Hypertension; Intracranial Pressure; Laser-Doppler Flowmetry; Liver Failure, Acute; Male; Models, Cardiovascular; Necrosis; Rats; Rats, Wistar; Water

2008
Glutamine preferentially inhibits T-helper type 2 cell-mediated airway inflammation and late airway hyperresponsiveness through the inhibition of cytosolic phospholipase A(2) activity in a murine asthma model.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:2

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Cytokines; Disease Models, Animal; Eosinophils; Female; Glutamine; Mice; Mice, Inbred BALB C; Mucus; Neutrophils; Phospholipases A2, Cytosolic; Phosphorylation; Th2 Cells

2008
Metabolic changes detected by proton magnetic resonance spectroscopy in vivo and in vitro in a murin model of Parkinson's disease, the MPTP-intoxicated mouse.
    Journal of neurochemistry, 2008, Volume: 105, Issue:3

    Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurochemistry; Neurotransmitter Agents; Parkinsonian Disorders; Protons; Substantia Nigra; Synaptic Transmission; Up-Regulation

2008
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder.
    Molecular psychiatry, 2009, Volume: 14, Issue:3

    Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Metabolomics; Middle Aged; Prefrontal Cortex; Rats; Rats, Inbred WKY; Reference Values

2009
l-Glutamine administration reduces oxidized glutathione and MAP kinase signaling in dystrophic muscle of mdx mice.
    Pediatric research, 2008, Volume: 63, Issue:3

    Topics: Age Factors; Animals; Antioxidants; Body Weight; Dietary Supplements; Disease Models, Animal; Down-Regulation; Glutamine; Glutathione; Glutathione Disulfide; Injections, Intraperitoneal; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-kappa B; Oxidative Stress; Phosphorylation; Time Factors; Tumor Necrosis Factor-alpha

2008
Oral glutamine prevents DMBA-induced mammary carcinogenesis via upregulation of glutathione production.
    Nutrition (Burbank, Los Angeles County, Calif.), 2008, Volume: 24, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Disease Models, Animal; Female; Glutamine; Glutathione; Killer Cells, Natural; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation

2008
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity.
    Behavioural pharmacology, 2008, Volume: 19, Issue:2

    Topics: Amphetamine; Animals; Antipsychotic Agents; Arousal; Brain; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glutamine; Injections, Intraperitoneal; Injections, Subcutaneous; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phenols; Psychotic Disorders; Receptors, Serotonin; Reflex, Startle; Sulfonamides; Synaptic Transmission

2008
Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.
    Neurobiology of disease, 2008, Volume: 30, Issue:3

    Topics: Animals; Arginine; Asparagine; Disease Models, Animal; Female; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Mice, Transgenic; Neuroprotective Agents; Nipecotic Acids; PC12 Cells; Rats; Tiagabine

2008
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease.
    Neurobiology of disease, 2008, Volume: 30, Issue:3

    Topics: Animals; Asparagine; Cell Differentiation; Cell Movement; Disease Models, Animal; Disease Progression; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Sertraline

2008
Effect of glutaurine on liver tumour development and acute leukaemia induced by MC29 virus in turkey poults.
    Acta microbiologica Hungarica, 1983, Volume: 30, Issue:1

    Topics: Animals; Avian Leukosis; Avian Leukosis Virus; Disease Models, Animal; Female; Glutamine; Liver Neoplasms, Experimental; Male; Poultry Diseases; RNA-Directed DNA Polymerase; Taurine; Turkeys

1983
Metabolism and transport of L-glutamine and L-alanine by renal tubules of chickens.
    The American journal of physiology, 1983, Volume: 245, Issue:2

    Topics: Acidosis, Respiratory; Alanine; Alkalosis, Respiratory; Animals; Biological Transport; Carbon Dioxide; Chickens; Disease Models, Animal; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules; Lactates; Lactic Acid; Renal Circulation

1983
Hepatocyte heterogeneity in ammonia metabolism: impairment of glutamine synthesis in CCl4 induced liver cell necrosis with no effect on urea synthesis.
    Chemico-biological interactions, 1984, Volume: 48, Issue:2

    Topics: Ammonia; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutamine; Liver Diseases; Male; Necrosis; Rats; Rats, Inbred Strains; Urea

1984
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy.
    Journal of neuroscience research, 1994, Aug-01, Volume: 38, Issue:5

    Topics: Animals; Cell Death; Disease Models, Animal; Gliosis; Glutamic Acid; Glutamine; Hippocampus; Histamine; Histamine Release; Male; Methylhistidines; Microdialysis; Necrosis; Nerve Degeneration; Neuroglia; Pyrithiamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy

1994
A diet producing a low diabetes incidence modifies immune abnormalities in diabetes-prone BB rats.
    The Journal of nutrition, 1995, Volume: 125, Issue:10

    Topics: Animals; Autoimmune Diseases; Cells, Cultured; Diabetes Mellitus; Diet; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glutamine; Immune System; Immunophenotyping; Incidence; Killer Cells, Natural; Lymph Nodes; Lymphocytes; Male; Rats; Rats, Inbred BB; Spleen; Thymidine

1995
Serial changes in metabolism and histology in the cold-injury trauma rat brain model--proton magnetic resonance imaging and spectroscopy study.
    Neurologia medico-chirurgica, 1995, Volume: 35, Issue:1

    Topics: Acetates; Animals; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Cold Temperature; Disease Models, Animal; Female; Glutamine; Glycolysis; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mitochondria; Rats; Rats, Wistar

1995
[Glutamine (Gln) supplementation in septic rats].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:10

    Topics: Animals; Disease Models, Animal; Female; Glutamine; Infections; Lymphocyte Activation; Male; Mononuclear Phagocyte System; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley

1993
Effect of sodium benzoate on cerebral and hepatic energy metabolites in spf mice with congenital hyperammonemia.
    Biochemical pharmacology, 1993, Jan-07, Volume: 45, Issue:1

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Ammonia; Animals; Benzoates; Benzoic Acid; Brain; Coenzyme A; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Liver; Male; Mice; Mice, Mutant Strains; Ornithine Carbamoyltransferase Deficiency Disease; Time Factors; Urea

1993
Effects of repeated cerebral ischemia on extracellular amino acid concentrations measured with intracerebral microdialysis in the gerbil hippocampus.
    Stroke, 1993, Volume: 24, Issue:3

    Topics: Amino Acids; Animals; Brain Ischemia; Disease Models, Animal; Extracellular Space; gamma-Aminobutyric Acid; Gerbillinae; Glutamine; Glycine; Hippocampus; Necrosis; Neurons; Taurine

1993
Starvation and endotoxin act independently and synergistically to coordinate hepatic glutamine transport.
    The Journal of trauma, 1996, Volume: 40, Issue:5

    Topics: Amino Acids; Analysis of Variance; Animals; Bacteremia; Biological Transport; Disease Models, Animal; Escherichia coli Infections; Glutamine; In Vitro Techniques; Lipopolysaccharides; Liver; Male; Rats; Rats, Inbred F344; Starvation

1996
Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse.
    Brain research. Developmental brain research, 1995, Dec-21, Volume: 90, Issue:1-2

    Topics: Ammonia; Animals; Brain Damage, Chronic; Disease Models, Animal; Glutamine; Hair; Metabolism, Inborn Errors; Mice; Mice, Inbred Strains; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Quinolinic Acid; Tryptophan

1995
Ornithine-alpha-ketoglutarate (OKG) supplementation is more effective than its component salts in traumatized rats.
    The Journal of nutrition, 1996, Volume: 126, Issue:9

    Topics: Amino Acids; Animals; Body Weight; Creatinine; Diet; Disease Models, Animal; Eating; Femoral Fractures; Food, Fortified; Glutamine; Glycine; Growth Hormone; Insulin; Ketoglutaric Acids; Male; Muscle, Skeletal; Nitrogen; Ornithine; Random Allocation; Rats; Rats, Sprague-Dawley; Urea; Wounds and Injuries

1996
Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs.
    The Journal of nutrition, 1996, Volume: 126, Issue:10

    Topics: Alanine; Animals; Aspartic Acid; Atrophy; Diet; Disease Models, Animal; Duodenum; Epithelium; Female; Glutamic Acid; Glutamine; Intestinal Diseases; Jejunum; Male; Stomach; Swine; Swine Diseases; Taurine; Weaning

1996
Neuronal and glial handling of glutamate and glutamine during hypoosmotic stress: a biochemical and quantitative immunocytochemical analysis using the rat cerebellum as a model.
    Neuroscience, 1996, Volume: 72, Issue:3

    Topics: Animals; Cerebellum; Disease Models, Animal; Glutamic Acid; Glutamine; Immunohistochemistry; Male; Microscopy, Electron; Neuroglia; Rats; Rats, Sprague-Dawley; Stress, Physiological

1996
Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitis.
    Gut, 1997, Volume: 41, Issue:4

    Topics: Analysis of Variance; Animals; Body Weight; Colitis; Colon; Diet; Disease Models, Animal; Drug Administration Schedule; Female; Glutamine; Interleukin-8; Intestinal Mucosa; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

1997
Changes in brain organic osmolytes in experimental cerebral ischemia.
    Journal of the neurological sciences, 1998, Apr-15, Volume: 157, Issue:1

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Magnetic Resonance Spectroscopy; Male; Methylamines; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine

1998
A fly's eye view of Huntington's disease.
    Nature, 1998, Oct-29, Volume: 395, Issue:6705

    Topics: Animals; Disease Models, Animal; Drosophila melanogaster; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Nerve Tissue Proteins; Nuclear Proteins; Photoreceptor Cells, Invertebrate; Recombinant Proteins

1998
Enteral glutamine does not enhance the effects of hepatocyte growth factor in short bowel syndrome.
    Journal of pediatric surgery, 1998, Volume: 33, Issue:11

    Topics: Adaptation, Physiological; Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; DNA; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Motility; Gastrostomy; Glutamine; Hepatocyte Growth Factor; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Reference Values; Short Bowel Syndrome

1998
Intravenous glutamine or limited enteral feedings in piglets: amelioration of small intestinal disuse atrophy.
    The Journal of nutrition, 1998, Volume: 128, Issue:12 Suppl

    Topics: Animals; Atrophy; beta-Galactosidase; Dietary Fats; Dietary Proteins; Disease Models, Animal; Energy Intake; Enteral Nutrition; Glutamine; Ileum; Intestine, Small; Jejunum; Lactase; Parenteral Nutrition, Total; Sucrase; Swine

1998
Different complex formations of dentatorubral-pallidoluysian atrophy (DRPLA) protein in human and rat neurons.
    Biochemical and biophysical research communications, 1998, Dec-18, Volume: 253, Issue:2

    Topics: Aged; Animals; Atrophy; Brain Diseases; Cerebral Cortex; Dentate Gyrus; Disease Models, Animal; Disulfides; Globus Pallidus; Glutamine; Humans; Immunohistochemistry; Intracellular Fluid; Middle Aged; Nerve Tissue Proteins; Rats

1998
Intravenous glutamine or short-chain fatty acids reduce central venous catheter infection in a model of total parenteral nutrition.
    Journal of pediatric surgery, 1999, Volume: 34, Issue:2

    Topics: Animals; Bacterial Translocation; Catheterization, Central Venous; Catheters, Indwelling; Chi-Square Distribution; Disease Models, Animal; Fatty Acids, Volatile; Glutamine; Intestinal Mucosa; Parenteral Nutrition, Total; Rats; Rats, Wistar; Sepsis

1999
Localized 15N NMR spectroscopy of rat brain by ISIS.
    Magnetic resonance in medicine, 1999, Volume: 41, Issue:3

    Topics: Acetates; Animals; Brain; Brain Mapping; Disease Models, Animal; Glutamine; Image Enhancement; Magnetic Resonance Spectroscopy; Male; Nitrogen Radioisotopes; Phantoms, Imaging; Rats; Rats, Wistar; Sensitivity and Specificity

1999
Food deprivation and refeeding influence growth, nutrient retention and functional recovery of rats.
    The Journal of nutrition, 1999, Volume: 129, Issue:7

    Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Capillary Permeability; Diet; Disease Models, Animal; Food; Glutamine; Growth; Intestinal Mucosa; Liver; Male; Muscles; Nitrogen; Rats; Rats, Wistar; Starvation; Weight Gain

1999
Does glutamine reduce bacterial translocation? A study in two animal models with impaired gut barrier.
    International journal of colorectal disease, 1999, Volume: 14, Issue:3

    Topics: Animals; Bacterial Translocation; Colitis; Colon; Dietary Supplements; Disease Models, Animal; Electrophysiology; Glutamine; Male; Pancreatitis; Parenteral Nutrition; Rats; Rats, Sprague-Dawley; Sepsis

1999
The role of glutamine in skeletal muscle ischemia/reperfusion injury in the rat hind limb model.
    American journal of surgery, 1999, Volume: 178, Issue:2

    Topics: Animals; Creatine Kinase; Disease Models, Animal; Glutamic Acid; Glutamine; Glutathione; Hindlimb; Injections, Intraperitoneal; Ischemia; Lipid Peroxidation; Male; Muscle, Skeletal; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Random Allocation; Rats; Rats, Inbred Strains; Reperfusion Injury; Single-Blind Method; Time Factors

1999
Huntington's disease. In reverse gear.
    Nature, 2000, Apr-27, Volume: 404, Issue:6781

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Gene Expression Regulation; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Mice; Nerve Tissue Proteins; Nuclear Proteins; Trinucleotide Repeats

2000
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
    Journal of neurochemistry, 2001, Volume: 76, Issue:1

    Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamine; Lactic Acid; Male; Pyruvic Acid; Quercetin; Rats; Rats, Sprague-Dawley

2001
Glutamine ameliorates mechanical obstruction-induced intestinal injury.
    The Journal of surgical research, 2001, Volume: 95, Issue:2

    Topics: Administration, Oral; Animals; Arginine; Cecum; Disease Models, Animal; Glutamine; Ileum; Intestinal Mucosa; Intestinal Obstruction; Intestine, Small; Male; Rats; Rats, Sprague-Dawley

2001
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Body Weight; Brain Chemistry; Creatine; Dicarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Microdialysis; Motor Activity; Motor Neuron Disease; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Oxidative Stress; Psychomotor Performance; Pyrrolidines; Superoxide Dismutase

2001
Protein hydrolysate vs free amino acid-based diets on the nutritional recovery of the starved rat.
    European journal of nutrition, 2000, Volume: 39, Issue:6

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Proteins; Disease Models, Animal; Enteral Nutrition; Glutamine; Growth; Intestinal Mucosa; Liver; Male; Muscles; Nitrogen; Protein Hydrolysates; Random Allocation; Rats; Rats, Wistar; Starvation; Weight Gain

2000
Feeding a protective hydrolysed casein diet to young diabetic-prone BB rats affects oxidation of L[U-14C]glutamine in islets and Peyer's patches, reduces abnormally high mitotic activity in mesenteric lymph nodes, enhances islet insulin and tends to norma
    International journal of experimental diabetes research, 2000, Volume: 1, Issue:2

    Topics: Administration, Oral; Animal Feed; Animals; Blood Glucose; Caseins; Diabetes Mellitus, Type 1; Dietary Proteins; Disease Models, Animal; Female; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Lymph Nodes; Male; Mitosis; Nitric Oxide; Oxidation-Reduction; Peyer's Patches; Protein Hydrolysates; Rats; Rats, Inbred BB; Reference Values; Weight Gain

2000
Glutamine transporter in crypts compensates for loss of villus absorption in bovine cryptosporidiosis.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:3

    Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Animals; Blotting, Western; Carrier Proteins; Cattle; Chlorides; Cryptosporidiosis; Cyclooxygenase Inhibitors; Dinoprostone; Dipeptides; Disease Models, Animal; Drug Synergism; Glutamine; Ileum; Immunohistochemistry; In Vitro Techniques; Indomethacin; Intestinal Absorption; Ion Transport; Sodium

2001
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
    Nature, 2001, Oct-18, Volume: 413, Issue:6857

    Topics: Acetylation; Acetyltransferases; Animals; Animals, Genetically Modified; CREB-Binding Protein; Disease Models, Animal; Drosophila; Drosophila Proteins; E1A-Associated p300 Protein; Enzyme Inhibitors; Gene Expression Regulation; Glutamine; Glutathione Transferase; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Huntingtin Protein; Huntington Disease; Nerve Degeneration; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; PC12 Cells; Peptides; Protein Structure, Tertiary; Rats; Repetitive Sequences, Amino Acid; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Trans-Activators

2001
Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:5

    Topics: Animals; Cytokines; Disease Models, Animal; Endotoxemia; Escherichia coli; Glutamine; Ileum; Interleukin-1; Interleukin-10; Lipopolysaccharides; Lung; Male; Rats; Rats, Sprague-Dawley; Sepsis; Time Factors; Tumor Necrosis Factor-alpha

2001
Bacterial translocation and glutamine.
    Nutrition (Burbank, Los Angeles County, Calif.), 2002, Volume: 18, Issue:5

    Topics: Animals; Bacterial Translocation; Disease Models, Animal; Glutamine; Intestines; Rats; Treatment Outcome

2002
Both glucose-insulin-potassium and glutamine in warm blood cardioplegia increase the rates of myocardial glucose and free fatty acid oxidation.
    Scandinavian cardiovascular journal : SCJ, 2002, Volume: 36, Issue:1

    Topics: Animals; Blood Glucose; Body Temperature Regulation; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glutamine; Heart Arrest, Induced; Hemodynamics; Insulin; Linear Models; Male; Myocardium; Potassium; Random Allocation; Reference Values; Sensitivity and Specificity; Swine; Time Factors

2002
Effects of an alanyl-glutamine-based oral rehydration and nutrition therapy solution on electrolyte and water absorption in a rat model of secretory diarrhea induced by cholera toxin.
    Nutrition (Burbank, Los Angeles County, Calif.), 2002, Volume: 18, Issue:6

    Topics: Animals; Cholera Toxin; Diarrhea; Dipeptides; Disease Models, Animal; Electrolytes; Female; Fluid Therapy; Glutamine; Intestinal Absorption; Kinetics; Male; Potassium; Rats; Rats, Wistar; Rehydration Solutions; Sodium; Water

2002
Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig.
    Nutrition (Burbank, Los Angeles County, Calif.), 2002, Volume: 18, Issue:6

    Topics: Acidosis; Alanine; Amino Acids; Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutamic Acid; Glutamine; Injections, Intravenous; Ketoglutaric Acids; Male; Muscle, Skeletal; Quaternary Ammonium Compounds; Random Allocation; Splanchnic Circulation; Swine; Urea; Viscera

2002
Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase.
    Journal of neurochemistry, 2002, Volume: 81, Issue:1

    Topics: Aldehyde Oxidoreductases; Animals; beta-Alanine; Blotting, Western; Brain; Carboxylic Acids; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamine; Kidney; Liver; Male; Mice; Mice, Knockout; Myocardium; Organ Specificity; Oxidation-Reduction; Pancreas; RNA, Messenger; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase

2002
Inhibitors of gastric lesions in the rat.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:4

    Topics: Animals; Aspirin; Disease Models, Animal; Female; Glutamine; Histamine Antagonists; Indomethacin; Ligation; Pylorus; Rats; Salicylates; Stomach Ulcer; Stress, Physiological

1978
Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures.
    Brain research, 1978, Nov-24, Volume: 157, Issue:2

    Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamates; Glutamine; Ketoglutaric Acids; Penicillins; Pyruvates; Rats; Seizures; Time Factors; Transaminases

1978
Effect of supplemental dietary glutamine on methotrexate concentrations in tumors.
    Archives of surgery (Chicago, Ill. : 1960), 1992, Volume: 127, Issue:11

    Topics: Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Energy Intake; Glutamine; Humans; Male; Methotrexate; Rats; Rats, Inbred F344; Sarcoma, Experimental

1992
Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat.
    Journal of neurosurgery, 1991, Volume: 74, Issue:5

    Topics: Amino Acids; Animals; Aspartic Acid; Blood Flow Velocity; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutamates; Glutamic Acid; Glutamine; Hematoma, Subdural; Male; Rats; Rats, Inbred Strains; Regression Analysis; Valine

1991
High-performance liquid chromatographic determination of selected amino acids in rat brain by precolumn derivatization with phenylisothiocyanate.
    Journal of chromatography, 1990, Mar-09, Volume: 503, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Isothiocyanates; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thiocyanates

1990
Effect of a new cholecystokinin receptor antagonist loxiglumide on acute pancreatitis in two experimental animal models.
    Pancreas, 1990, Volume: 5, Issue:3

    Topics: Acute Disease; Animals; Ceruletide; Cholecystokinin; Disease Models, Animal; Glutamine; Male; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Taurocholic Acid

1990
Oral glutamine accelerates healing of the small intestine and improves outcome after whole abdominal radiation.
    Archives of surgery (Chicago, Ill. : 1960), 1990, Volume: 125, Issue:8

    Topics: Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Enteritis; Glutamine; Glycine; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains

1990
[Neurotropic fungal metabolites].
    Seikagaku. The Journal of Japanese Biochemical Society, 1989, Volume: 61, Issue:3

    Topics: Animals; Disease Models, Animal; Dopamine Agents; Epilepsy; Glutamine; Mice; Mycotoxins; Receptors, Amino Acid; Receptors, Cell Surface

1989
Nephritogenic glycoprotein. XII. Focal glomerulonephritis with myeloid bodies produced in rats by synthetic analogues of the glycopeptide, nephritogenoside.
    Nephron, 1987, Volume: 47, Issue:2

    Topics: Animals; Asparagine; Cells, Cultured; Disease Models, Animal; Fluorescent Antibody Technique; Glomerulonephritis; Glutamine; Glycopeptides; Humans; Inclusion Bodies; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred Strains; Trisaccharides

1987
A possible drug interaction between aspirin and L-glutamine on some experimental inflammatory and analgesic models.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Drug Interactions; Female; Glutamine; Inflammation; Male; Mice; Mice, Inbred Strains; Pain; Rats

1988
Experimental acute pancreatitis induced by excessive doses of caerulein in rats; protective and therapeutic effects of trypsin inhibitor urinastatin and CCK receptor antagonist CR1392.
    The Kobe journal of medical sciences, 1988, Volume: 34, Issue:2

    Topics: Acute Disease; Animals; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Glycoproteins; Kinetics; Male; Microscopy, Electron; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Trypsin Inhibitors

1988
[Enzymes of glutamine metabolism in the brain in acute hypoxic hypoxia].
    Ukrains'kyi biokhimichnyi zhurnal, 1973, Volume: 45, Issue:1

    Topics: Acute Disease; Animals; Brain; Brain Chemistry; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Hypoxia, Brain; Rabbits; Transaminases

1973
Renal ammoniagenesis and tissue glutamine, glutamine synthetase, and glutaminase I levels in potassium-deficient rats.
    The Journal of laboratory and clinical medicine, 1973, Volume: 82, Issue:2

    Topics: Ammonia; Animals; Carbon Dioxide; Chlorides; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kidney; Liver; Male; Muscles; Organ Size; Potassium; Potassium Deficiency; Rats; Renal Veins; Sodium

1973
Ultrastructural responses of the astrocytes to portocaval anastomosis in the rat.
    Journal of the neurological sciences, 1973, Volume: 18, Issue:1

    Topics: Ammonia; Animals; Brain; Brain Diseases; Carbon Tetrachloride Poisoning; Caudate Nucleus; Cerebellar Nuclei; Chemical and Drug Induced Liver Injury; Cytoplasm; Disease Models, Animal; Glutamates; Glutamine; Liver Diseases; Male; Microscopy, Electron; Nerve Degeneration; Nerve Fibers, Myelinated; Neuroglia; Nitrosamines; Portacaval Shunt, Surgical; Rats

1973
Therapeutic properties of a new glutaminase-asparaginase preparation and the influence of the lactate dehydrogenase-elevating virus.
    Cancer research, 1974, Volume: 34, Issue:2

    Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamates; Glutaminase; Glutamine; Half-Life; Hydrogen-Ion Concentration; Isoelectric Focusing; L-Lactate Dehydrogenase; Leukemia, Experimental; Mice; Mice, Inbred C57BL; RNA Viruses

1974
Abnormal orotic acid metabolism associated with acute hyperammonaemia in the rat.
    Biochemical medicine, 1974, Volume: 9, Issue:1

    Topics: Acetates; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Disease Models, Animal; Electrophoresis, Paper; Glutamates; Glutamine; Hydrogen-Ion Concentration; Liver; Male; Mass Spectrometry; Orotic Acid; Pentosyltransferases; Purine Nucleotides; Quaternary Ammonium Compounds; Rats; Time Factors; Uracil Nucleotides

1974
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
    Brain research, 1974, Jun-20, Volume: 73, Issue:2

    Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Dioxide; Citrates; Disease Models, Animal; Glucose; Glutamates; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Nucleotidases; Oxidation-Reduction; Partial Pressure; Phosphocreatine; Pyruvates; Rats

1974
Cerebral metabolic state following complete compression ischemia.
    Brain research, 1974, Jun-20, Volume: 73, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Blood Pressure; Carbohydrate Metabolism; Carbon Dioxide; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Electroencephalography; Glucose; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Mitochondria; Nucleotidases; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats; Time Factors

1974
Phenylketonuria and glutamine.
    The New England journal of medicine, 1970, Jun-25, Volume: 282, Issue:26

    Topics: Animals; Disease Models, Animal; Glutamine; Haplorhini; Humans; Intellectual Disability; Phenylketonurias; Rats

1970
Renal metabolism of glutamine in dogs during infusion of -ketoglutaric acid.
    The American journal of physiology, 1972, Volume: 222, Issue:3

    Topics: Acidosis; Ammonia; Ammonium Chloride; Animals; Cell Membrane Permeability; Disease Models, Animal; Dogs; Female; Glutaminase; Glutamine; Ketoglutaric Acids; Kidney; Male; Membranes; Mitochondria; Permeability

1972
Phenylketonuria and glutamine.
    The New England journal of medicine, 1970, Jun-25, Volume: 282, Issue:26

    Topics: Animals; Disease Models, Animal; Female; Glutamates; Glutamine; Humans; Infant, Newborn; Intellectual Disability; Phenylketonurias; Placenta; Pregnancy; Rats

1970