glutamine has been researched along with Disease Models, Animal in 459 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (4.14) | 18.7374 |
1990's | 32 (6.97) | 18.2507 |
2000's | 145 (31.59) | 29.6817 |
2010's | 207 (45.10) | 24.3611 |
2020's | 56 (12.20) | 2.80 |
Authors | Studies |
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Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Guo, S; Huang, B; Jiang, S; Mao, X; Mo, C; Zhuang, J | 1 |
Aldana, BI; Andersen, JV; Christensen, SK; Diaz-delCastillo, M; Freude, KK; Gentry, MS; Haukedal, H; Kohlmeier, KA; Mann, M; Markussen, KH; Polli, FS; Schousboe, A; Shabani, M; Skotte, NH; Sun, RC; Tanila, H; Waagepetersen, HS; Westi, EW | 1 |
Beldi, VFM; Evora, PRB; Farina Junior, JA; Jordão, AA; Moriguti, EKU; Rosique, MJ; Tirapelli, DPC; Tirapelli, LF | 1 |
Burczynski, ME; Chen, H; Cheng, X; Halasz, G; Kim, S; Lin, AZ; Mao, X; Murphy, AJ; Na, E; Okamoto, H; Sleeman, MW | 1 |
Gao, Y; He, Z; Li, T; Luo, C; Ou, L; Yu, C | 1 |
Huang, Y; Ji, P; Liu, C; Liu, SJ; Wang, N; Yu, Y; Zhang, B; Zhao, F; Zuo, Z | 1 |
Adeyemi, DH; Afolabi, OA; Akhigbe, RE; Anyogu, DC; Hamed, MA; Odetayo, AF | 1 |
Chao de la Barca, JM; Eid, M; Fassot, C; Faure, J; Fouquet, O; Henrion, D; Loufrani, L; Reynier, P; Richard, A; Robert, P; Tessier, L; Wetterwald, C | 1 |
Beracochea, D; Dore, J; Dries, A; Faucher, P; Leboyer, M; Mousset, PY | 1 |
Liu, J; Song, M | 1 |
Cao, L; Fan, HT; Li, JL; Song, R; Yang, HT; Yang, XF; Zhong, L; Zhou, HX | 1 |
Almeida, GM; Ayupe, MC; Caldini, EG; Carregari, VC; Costa, L; Crunfli, F; Cunha, TM; D'Império Lima, MR; da Silva, P; Davanzo, GG; de Almeida Campos, AC; de Araújo, MV; de Oliveira, LG; de Oliveira, MG; de Sá Guimarães, AM; de Souza Angelo, Y; de Souza Filho, AF; Dos Passos Cunha, M; Dos Santos, NB; Duque, ÉA; Firmino, EM; Fonseca, DM; Góes, LGB; Martins-de-Souza, D; Minoprio, PC; Moraes-Vieira, PM; Mori, CMC; Munhoz, CD; Paiva, IM; Peron, JPS; Polonio, CM; Reis-de-Oliveira, G; Salgado, CL; Sebollela, A; Silva-Pereira, TT; Vendramini, PH; Yamamoto, P; Zanluqui, NG | 1 |
Chen, X; Craig, MC; Feng, J; Murphy, ST; Seo, Y; Yuneva, M | 1 |
Aliakbarzadeh, F; Hashemi, R; Khodagholi, F; Motamedi, F; Naderi, N; Naderi, S; Pourbadie, HG; Sayehmiri, F | 1 |
Kong, P; Liu, F; Tang, S; Wang, Q; Wu, R | 1 |
Anthony, DC; Augusto-Oliveira, M; Bayuangga, H; Claridge, TDW; Kuhle, J; Leppert, D; Palace, J; Probert, F; Sealey, M; Tanner, R; Yeo, T | 1 |
Anarat-Cappillino, G; Belanger, AJ; Gefteas, E; Geller, S; Kloss, A; Przybylska, M; Yew, NS | 1 |
Jiang, M; Jin, H; Li, Y; Lian, N; Lu, X; Mao, J; Qi, X; Qi, Y; Xi, B; Zhang, C; Zhao, F; Zhu, W | 1 |
Claeys, W; Geerts, A; Ghesquière, B; Lefere, S; Van Hoecke, L; Van Imschoot, G; Van Steenkiste, C; Van Vlierberghe, H; Van Wonterghem, E; Vandenbroucke, RE | 1 |
Brown, K; De Nardo, W; De Souza, DP; Fidelito, G; Keerthikumar, S; Niranjan, B; Taylor, RA; Watt, MJ | 1 |
Bae, SW; Cohen, AS; Geng, L; Georgiou, DK; Manning, HC; Tantawy, MN; Wang, J; Wen, X | 1 |
Cai, Z; Chen, Y; Shi, Y; Sun, Y; Wang, J; Wang, Q; Wang, W; Zhang, H; Zhang, X | 1 |
Dąbrowska-Bouta, B; Sidoryk-Węgrzynowicz, M; Strużyńska, L; Sulkowski, G | 1 |
Baek, JH; Kang, JS; Kim, HJ; Lee, DK; Song, M | 1 |
Fan, Q; Hanse, EA; Kong, M; Lowman, XH; Ruiz, BI; Wang, T; Wu, H; Yang, Y | 1 |
Butterfield, DA; Hinchie, A; Powell, DK; Ren, X; Swomley, A | 1 |
Allegri, G; Burke, KE; Cederbaum, SD; Häberle, J; Lipshutz, GS; Liu, XB; Martini, PGV; Truong, B; Zhu, X | 1 |
Bona, S; Carvalho, C; de Oliveira, CM; Dresch, DF; Guma, FCR; Marroni, NP; Martins, LAM; Medeiros, PC; Petry, ÉR; Rosa, TG; Schemitt, E; Wannmacher, CMD | 1 |
He, Y; Jin, H; Sun, Z; Wan, H; Yu, L; Zhou, H | 1 |
Aguilar, JMH; Alt, J; Blakeley, JO; Brayton, C; Dash, RP; Lam, J; Lemberg, KM; Majer, P; Nedelcovych, MT; Rais, R; Rodriguez, C; Slusher, BS; Tenora, L; Veeravalli, V; Wu, Y; Zhao, L | 1 |
Gao, Y; Guo, Y; Liu, Y; Lu, F; Piao, Y; Tan, S; Tang, Y | 1 |
Chen, C; Du, G; Gao, X; Qin, X; Tian, J; Yin, Q; Zhou, Y | 1 |
Abdelmalek, MF; Bashir, MR; Chitneni, SK; Diehl, AM; Du, K; Henao, R; Hyun, J; Moylan, CA; Naggie, S; Premont, RT; Suzuki, A; Wang, Y | 1 |
Cui, ZH; Rong, D; Shang, HQ; Wang, X; Zhang, XJ | 1 |
Barbosa, AM; Beauparlant, CJ; Carvalho, A; Cunha, C; Droit, A; Estaquier, J; Ferreira, C; Mesquita, I; Osório, NS; Saha, B; Silvestre, R; Torrado, E | 1 |
Baek, JH; Jung, S; Kang, JS; Kim, HJ; Son, H | 1 |
Huang, CC; Lee, PC; Lin, MT; Pai, MH; Wu, JM; Yang, PJ; Yeh, SL | 1 |
Braissant, O; Cudalbu, C; McLin, VA; Rackayova, V; Rougemont, AL | 1 |
Alt, J; Blue, ME; Fowler, A; Kannan, RM; Kannan, S; Khoury, ES; Rais, R; Ramireddy, RR; Sharma, A; Slusher, B; Thomas, AG; Tsukamoto, T | 1 |
Hazen, SL; Weeks, TL; Witkowski, M | 1 |
Cao, G; Deng, L; Gao, Y; Guo, C; Hao, J; Li, P; Li, Z; Song, Y; Sun, G; Tian, Y; Wang, X; Xia, X; Yin, Z; Zhang, H; Zhong, J; Zhou, W; Zhu, L | 1 |
Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; Laskin, J; Le, VH; Leach, M; Lee, BG; Lee, DF; Lee, DS; Lee, HJ; Lee, SB; Lee, YA; Lei, Y; Lekashvili, O; Lelj, F; Lemin, AS; Lemoine, J; Leuschner, R; Li, B; Li, BT; Li, C; Li, D; Li, F; Li, G; Li, H; Li, HW; Li, J; Li, M; Li, P; Li, Q; Li, S; Li, W; Li, X; Li, XY; Li, Y; Li, Z; Lian, Y; Liang, C; Liao, J; Liao, W; Liao, Y; Lin, D; Lin, W; Lin, YL; Lindbäck, J; Lindsay, AP; Ling, J; Linser, PJ; Liu, C; Liu, H; Liu, JJ; Liu, L; Liu, Q; Liu, SF; Liu, X; Liu, Y; Liu, Z; Liu, ZM; Lo Sterzo, C; Lo, ECM; Lobchuk, MM; Lodge, TP; Logotheti, S; Lonial, S; Lopes, G; Lopes, RD; Lopez, J; Lopez, SA; López-Santos, AL; López-Sendón, JL; Loring, Z; Louis, C; Lovita, AND; Lu, DZ; Lu, H; Lu, J; Lu, K; Lu, TT; Lu, Y; Luengo, A; Lum, LG; Luna, JM; Luo, L; Luo, R; Luo, T; Luo, X; Luo, Z; Lv, B; Lymperopoulos, N; Lyras, A; Lyu, Y; M Kannan, A; Ma, H; Ma, M; Ma, Q; Ma, S; Ma, WY; Ma, Y; Maalouf, E; Machado, FA; Maeda, K; Magrans, JO; Maharani, A; Maia, G; Mainwaring, RD; Maji, TK; Majumdar, K; Mannarino, MR; Mansuri, MS; Marinescu, SC; Markatos, G; Marquardt, S; Marraiki, N; Martens, C; Martínez, TJ; Marumo, K; Maruyama, H; Marwani, HM; Marzo, I; Masrati, G; Matamba, P; Mathialagan, S; Matys, J; Mayatra, JM; Mboua, PC; McArthur, T; McCrimmon, RJ; McIntosh, S; McSpadden, S; Medina-Campos, ON; Medvedovsky, AT; Mei, Z; Mekontso-Dessap, A; Menezes, AMB; Meng, J; Meng, P; Meng, Y; Menter, A; Mets, MB; Mets-Halgrimson, R; Metzger, T; Metzler-Nolte, N; Meyer, C; Mi, Y; Michailoviene, V; Mikrogeorgiou, A; Militz, H; Miller Iii, TF; Minarowska, A; Mir, S; Miron, I; Miyake, T; Moayer, F; Modi, S; Moeller, SJ; Mohamad, MN; Mohammed, EHM; Mokhonov, VV; Mondal, A; Moore, J; Moravcova, M; Mordi, IR; Mordi, NA; Mortensen, NP; Moscariello, C; Moser, J; Moynahan, ME; Mu, J; Mu, W; Mudduwa, LKB; Mukherjee, S; Mukhtar, A; Mulkey, DK; Murr, N; Mushtaq, Z; Muthuswamy, N; Mutlu, O; Muto, C; Myroforou, I; Na, KJ; Nabi, M; Nagornov, KO; Nagy, RJ; Naik, A; Nakajima, K; Nam, KT; Nam, YW; Namburath, M; Nammour, S; Namour, A; Namour, M; Nanan, S; Natsume, H; Nave, S; Naveed, A; Nazir, H; Ndubaku, C; Nedospasov, SA; Neradilek, MB; Newcomb, C; Nguépy Keubo, FR; Nguyen, M; Ning, J; Ning, Q; Noguchi, S; Nordahl, SHG; Nordfalk, KF; Norton, L; Noupoue, EM; Nouri, SS; Nowak, JK; Núñez, K; Oakes, K; Odegaard, JI; Ogorodnikova, OL; Ogunsuyi, O; Oh, HK; Oh, HR; Oh, KH; Ohgi, K; Okunade, KS; Oliveira, AG; Olorunfemi, G; Olsen, ML; Olson, BA; Omari, KW; Ondruschka, B; Orfali, R; Orkopoulos, A; Orlowski, RZ; Oser, SM; Oser, TK; Özcan, M; Padilla, V; Paeng, JC; Pajuelo-Lozano, N; Pal, SK; Palmieri, S; Palomeque, E; Pan, W; Panagiotakos, DB; Pandey, M; Pang, D; Pang, Q; Pangarah, CA; Panny, A; Paparella, A; Papirio, S; Papouskova, K; Parang, K; Park, HJ; Park, IK; Park, S; Parker, TL; Parkhomenko, A; Parmon, VN; Parsons, B; Parsons, J; Patel, PR; Patil, S; Patsourakos, NG; Patterson, KC; Pavlidis, P; Pedernera, M; Pedersen, R; Pedraza-Chaverri, J; Pellegrini, M; Peña-Chora, G; Pereira, EDM; Pereira, MADS; Peretz, A; Perez-Padilla, R; Perlman, GY; Perona, R; Petras, C; Phuntsho, S; Picada, JN; Pinder, TA; Piper, LFJ; Pirozzi, F; Pirro, M; Pleckaityte, M; Ploutz-Snyder, LL; Ploutz-Snyder, R; Pogorzelski, A; Poles, L; Postma, AA; Prager, A; Prakash, J; Punn, R; Pützer, BM; Qi, J; Qi, MC; Qi, Y; Qian, J; Qian, Y; Qiang, L; Qiu, J; Qu, Y; Rabiu, KA; Rahighi, S; Rahman, MM; Rahmani, B; Rajkumar, SV; Ramanathan, R; Raras, TYM; Rashi, Y; Rasool, G; Rathore, MG; Ratnawati, R; Ratola, N; Raucci, U; Ray, SK; Razavi, P; Razazi, K; Razek, S; Razi, SS; Reback, M; Reddy, K; Rees, DC; Reginatto, FH; Reich, H; Reis-Filho, JS; Ren, X; Ren, Y; Renner, G; Rey, G; Reymen, B; Riaz, M; Ricci, A; Richardson, PG; Richter, C; Riga, M; Ritchie, C; Rivoal, S; Roberts, W; Robson, ME; Rocha, GZ; Rodrigues, AD; Rogach, AL; Rojas, A; Rosenberg, A; Rosenberg, E; Rosenheck, RA; Roslan, K; Rothenberger, C; Rouschop, KMA; Rubagumya, F; Ryan, CM; Ryder, JW; Saad, MJA; Sacan, O; Sacchi, A; Sahebkar, A; Saini, A; Sainz, B; Sajo, EA; Sakizadeh, J; Saleh, AA; 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Bonnel, E; Lêvêque, L; Meynial-Denis, D; Mignon, M | 1 |
Fillmann, H; González-Gallego, J; Kretzmann, NA; Llesuy, S; Marroni, N; San-Miguel, B; Tuñón, MJ | 1 |
Belmonte, L; Coëffier, M; Daveau, M; Déchelotte, P; Ducrotté, P; Hecketsweiler, B; Hiron, M; Le Pessot, F; Lemeland, JF; Leplingard, A; Miralles-Barrachina, O | 1 |
Ceylan, A; Güven, H; Kara, N; Kaya, E; Yildiz, L | 1 |
Belanger, M; Davies, NA; Jalan, R; Nedredal, GI; Revhaug, A; Rose, C; Sen, S; Ytrebø, LM | 1 |
Bastholm, IA; Melø, TM; Nehlig, A; Sonnewald, U | 1 |
Kanamatsu, T; Nambu, A; Okamoto, K; Otsuki, T; Takada, M; Tokuno, H; Tsukada, Y; Umeda, M; Watanabe, H | 1 |
Kaufmann, Y; Klimberg, VS | 1 |
Bacha, E; Bolotin, G; Jeevanandam, V; Kocherginsky, M; Raman, J; Williams, U | 1 |
Dethloff, TJ; Knudsen, GM; Larsen, FS | 1 |
Cho, BH; Im, SY; Jin, ZW; Jung, YJ; Kang, NI; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, YM; Shin, YH | 1 |
Bielicki, G; Chassain, C; Durand, E; Durif, F; Essafi, F; Lolignier, S; Traoré, A | 1 |
Bahn, S; Griffin, JL; Holmes, E; Huang, JT; Lan, MJ; Manji, H; McLoughlin, GA; Tsang, TM; Yuan, P | 1 |
Constantin, B; Delwail, A; Favreau, F; Hankard, R; Magaud, C; Mok, E; Neveux, N | 1 |
Kaufmann, Y; Klimberg, VS; Spring, P | 1 |
Atack, JR; Boggs, JD; Bonaventure, P; Galici, R; Miller, KL | 1 |
Duan, W; Jiang, M; Li, Q; Liang, Y; Masuda, N; Peng, Q; Ross, CA; Wang, W; Wang, X; Zhao, M | 1 |
Cadet, JL; Duan, W; Ford, E; Ladenheim, B; Masuda, N; Peng, Q; Ross, CA; Tryggestad, E; Wong, J; Zhao, M | 1 |
Bátkai, L; Feuer, L; Nagy, K; Tálas, M | 1 |
Craan, AG; Gougoux, A; Lemieux, G; Vinay, P | 1 |
Gerok, W; Häussinger, D | 1 |
Barke, KE; Hough, LB; Langlais, PJ; Weilersbacher, G; Zhang, SX | 1 |
Field, CJ | 1 |
Abe, H; Hida, K; Houkin, K; Iwasaki, Y; Kamada, K | 1 |
Lowry, SF; Thompson, WA | 1 |
Kaibara, A; Kakegawa, T; Mizote, H; Yamasaki, K; Yoshida, S | 1 |
Butterworth, RF; Qureshi, IA; Ratnakumari, L | 1 |
Kato, H; Kogure, K; Nakata, N | 1 |
Bode, BP; Fischer, CP; Souba, WW | 1 |
Batshaw, ML; Heyes, MP; Hopkins, K; McLaughlin, BA; Oster-Granite, ML; Robinson, MB | 1 |
Holaday, NJ; Jeevanandam, M; Petersen, SR | 1 |
Knabe, DA; Meier, SA; Wu, G | 1 |
Blüml, S; Danielsen, ER; Ross, BD | 1 |
Lehmann, A; Nagelhus, EA; Ottersen, OP | 1 |
Blei, AT | 1 |
Adjei, AA; Ameho, CK; Arakaki, Y; Harrison, EK; Ito, E; Kawajiri, A; Kulkarni, AD; Morioka, T; Suzuki, I; Takeshita, K; Yamamoto, S | 1 |
Hayakawa, T; Kohmura, E; Nonaka, M; Wakayama, A; Yamashita, T; Yoshimine, T | 1 |
Mitchell, A | 1 |
Alavi, K; Kato, Y; Schwartz, MZ; Yu, D | 1 |
Dudgeon, DL; Guerino, F; Remillard, RL; Yardley, JH | 1 |
Hazeki, N; Kanazawa, I; Yazawa, I | 1 |
Lloyd, DA; McAndrew, HF; Rintala, R; van Saene, HK | 1 |
Ballévre, O; Boza, JJ; Donnet, A; Fritsché, R; Gaudard-de-Weck, D; Jarret, AR; Möennoz, D; Perruisseau, G; Schiffrin, EJ; Vuichoud, J | 1 |
Buhr, HJ; Eibl, G; Foitzik, T; Hotz, HG; Kroesen, AJ; Kruschewski, M | 1 |
Eppinger, M; Lemmon, G; Miller, S; Nolan, D; Peoples, J; Prem, JT | 1 |
Bates, G | 1 |
Hanna, MK; Kudsk, KA | 1 |
O'Regan, MH; Phillis, JW; Ren, J | 1 |
Chang, T; Lu, R; Tsai, L | 1 |
Foitzik, T | 1 |
Andreassen, OA; Beal, MF; Bogdanov, MB; Dedeoglu, A; Ferrante, KL; Jenkins, BG; Kaddurah-Daouk, R | 1 |
Ballèvre, O; Boza, JJ; Gaudard-de-Weck, D; Jarret, AR; Moënnoz, D; Vuichoud, J | 1 |
Ladrière, L; Laghmich, A; Malaisse, WJ; Olivares, E; Scott, FW; Sener, A | 1 |
Fürst, P | 1 |
Jonas, CR; Ziegler, TR | 1 |
Argenzio, R; Blikslager, A; Guerrant, R; Hunt, E; Rhoads, M | 1 |
Ishibashi, N; Kaibara, A; Shirouzu, K; Yoshida, S | 1 |
Behar, KL; Rothman, DL | 1 |
Karinch, AM; Lin, CM; Pan, M; Souba, WW; Strange, R | 1 |
Ziegler, TR | 1 |
Apostol, BL; Bodai, L; Greenwald, M; Housman, DE; Jackson, GR; Kazantsev, A; Kurokawa, R; Marsh, JL; McCampbell, A; Pallos, J; Poelman, M; Schmidt, E; Steffan, JS; Thompson, LM; Zhu, YZ | 1 |
Grimble, RF | 1 |
Chang, EB; Kahana, M; Musch, MM; Ren, H; Wischmeyer, PE; Wolfson, R | 1 |
Scolapio, JS | 1 |
Campos, AC; Salvalaggio, PR | 1 |
Elvenes, OP; Irtun, O; Korvald, C; Larsen, T; Sørlie, D | 1 |
Ball, PA; Hardy, G | 1 |
Carvalho, GH; Figueiredo, AA; Gifoni, AR; Guerrant, RL; Lima, AA; Silva, EA; Soares, AM | 1 |
Karlsson, T; Nordgren, A; Wiklund, L | 1 |
Bartels, H; Bottiglieri, T; Burlingame, TG; Froestl, W; Gibson, KM; Grompe, M; Guerand, WS; Gupta, M; Hogema, BM; Jakobs, C; Schor, DS; Senephansiri, H; Snead, OC | 1 |
Hayden, LJ; Thomas, G; West, GB | 1 |
Collins, RC; Mehta, S | 1 |
Broadwater, JR; Jensen, JC; Klimberg, VS; Lang, NP; Nwokedi, E; Pappas, AA; Westbrook, KC | 1 |
Bullock, R; Butcher, SP; Chen, MH; Kendall, L; McCulloch, J | 1 |
Gunawan, S; Treiman, DM; Walton, NY | 1 |
Fujii, M; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
Bland, KI; Bova, FC; Copeland, EM; Dolson, DJ; Hautamaki, RD; Kasper, M; Klimberg, VS; Mendenhall, WR; Plumley, DA; Salloum, RM | 1 |
Yamazaki, M | 1 |
Natori, Y; Okada, M; Oshima, M; Shibata, S; Shindo, N | 1 |
Godhwani, JL; Jain, P; Khanna, NK | 1 |
Tani, S | 1 |
Deriabina, TI; Savel'eva, SN | 1 |
Ching, S; Gabuzda, GJ; Rogoff, TM | 1 |
Cavanagh, JB; Kyu, MH; Zamora, AJ | 1 |
Dolowy, WC; Fitzmaurice, MA; Holcenberg, JS; Riley, V; Roberts, J; Spackman, D | 1 |
Abzug-Horowitz, S; Pinson, A; Russell, A; Statter, M | 1 |
Ljunggren, B; Schutz, H; Siesjö, BK | 1 |
Ljunggren, B; Ratcheson, RA; Siesjö, BK | 1 |
Perry, TL | 1 |
Balagura-Baruch, S; Welbourne, TC | 1 |
Cone, AL; Dierks-Ventling, C | 1 |
30 review(s) available for glutamine and Disease Models, Animal
Article | Year |
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Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease Models, Animal; Fatty Acids, Volatile; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Glutamine; Host Microbial Interactions; Humans; Methylamines; Mice; Mice, Inbred C57BL; Signal Transduction; Thrombosis; Vasculitis | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Disease Models, Animal; Drug Resistance, Neoplasm; Glutaminase; Glutamine; Humans; Neoplasms; NF-E2-Related Factor 2; Oxidative Stress; Thiadiazoles; Tumor Escape; Tumor Microenvironment | 2021 |
Dissecting drug effects in preclinical models of impulsive choice: emphasis on glutamatergic compounds.
Topics: Animals; Choice Behavior; Delay Discounting; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Humans; Impulsive Behavior; Reinforcement, Psychology | 2018 |
Branched-chain amino acids and ammonia metabolism in liver disease: therapeutic implications.
Topics: Amino Acids, Branched-Chain; Ammonia; Animals; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Humans; Ketoglutaric Acids; Kidney; Liver Cirrhosis; Muscle, Skeletal; Phenylbutyrates | 2013 |
PET and MR imaging of neuroinflammation in hepatic encephalopathy.
Topics: Amino Acid Transport System X-AG; Animals; Blood-Brain Barrier; Brain; Brain Edema; Cytokines; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Imidazoles; Inflammation; Isoquinolines; Magnetic Resonance Imaging; Microglia; Mitochondria; Multimodal Imaging; Neuroimaging; Portacaval Shunt, Surgical; Positron-Emission Tomography; Psychometrics; Pyrazoles; Pyrimidines; Rats | 2015 |
The role of immunomodulators on intestinal barrier homeostasis in experimental models.
Topics: Animals; Arginine; Bifidobacterium; Citrulline; Disease Models, Animal; Epithelial Cells; Fatty Acids, Omega-3; Glutamine; Homeostasis; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Intestinal Mucosa; Lactobacillus; Linoleic Acids, Conjugated; Permeability; Probiotics; Saccharomyces; Tryptophan | 2015 |
Critical Evaluation of the Changes in Glutamine Synthetase Activity in Models of Cerebral Stroke.
Topics: Animals; Astrocytes; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Reperfusion Injury; Stroke | 2015 |
Prevention and treatment of cancers by immune modulating nutrients.
Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes | 2016 |
Neurocircuitry for modeling drug effects.
Topics: Algorithms; Animals; Behavior, Addictive; Brain; Corticotropin-Releasing Hormone; Disease Models, Animal; Glutamine; Humans; Neural Pathways; Neurotransmitter Agents; Norepinephrine; Rats; Receptors, GABA; Reinforcement, Psychology; Serotonin; Substance-Related Disorders; Synaptic Transmission | 2012 |
Mutant mouse models in evaluating novel approaches to antipsychotic treatment.
Topics: Animals; Antipsychotic Agents; Carrier Proteins; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Mice; Nerve Tissue Proteins; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission | 2012 |
Enteral feeding and gut atrophy.
Topics: Adaptation, Physiological; Animals; Atrophy; Bacterial Translocation; Disease Models, Animal; Enteral Nutrition; Fasting; Gastrointestinal Hormones; Glutamine; Humans; Intestinal Mucosa; Rats; Swine | 2002 |
Adaptation following intestinal resection: mechanisms and signals.
Topics: Animals; Biomarkers; Disease Models, Animal; Epidermal Growth Factor; Glucagon-Like Peptides; Glucocorticoids; Glutamine; Growth Hormone; Humans; Insulin-Like Growth Factor I; Intestinal Absorption; Intestinal Mucosa; Intestines; Peptides; Short Bowel Syndrome | 2003 |
Hepatocarcinogenesis tumor grading correlated with in vivo image-guided 1H-NMR spectroscopy in a rat model.
Topics: Animals; Disease Models, Animal; Glutamine; Glycine; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Inbred F344; Reference Standards | 2005 |
[Drug-craving animal models and mechanisms].
Topics: Acetylcholine; Animals; Cannabinoid Receptor Modulators; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine; Glutamine; Norepinephrine; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Reward; Stress, Physiological; Substance-Related Disorders | 2005 |
Genetic mouse models of schizophrenia: from hypothesis-based to susceptibility gene-based models.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Genetic Predisposition to Disease; Glutamine; Mice; Models, Genetic; Schizophrenia | 2006 |
[Advances in neurobiological understanding of schizophrenia. Perspectives for new therapeutic concepts].
Topics: Animals; Aspartic Acid; Brain; Carrier Proteins; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Neuregulin-1; Neurons; Neuropil; Risk Factors; Schizophrenia; Synaptic Transmission | 2006 |
Nutrient modification of inflammatory mediator production.
Topics: Bacteremia; Capillary Permeability; Critical Illness; Cytokines; Dietary Fats; Digestive System Physiological Phenomena; Disease Models, Animal; Energy Metabolism; Enteral Nutrition; Glutamine; Humans; Immunocompetence; Inflammation; Parenteral Nutrition, Total; Stress, Physiological; Survival Rate | 1994 |
Proton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?
Topics: Animals; Astrocytes; Brain; Choline; Cognition Disorders; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Humans; Hydrogen; Inositol; Liver Cirrhosis; Liver Transplantation; Magnetic Resonance Spectroscopy; Portasystemic Shunt, Transjugular Intrahepatic; Protons | 1996 |
Pathogenesis of brain edema in fulminant hepatic failure.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Humans; Intracranial Pressure; Sodium-Potassium-Exchanging ATPase | 1995 |
Nutritional and pharmacological enhancement of gut-associated lymphoid tissue.
Topics: Animals; Bacterial Translocation; Bombesin; Critical Illness; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Immunity, Mucosal; Intestinal Mucosa; Intestines; Lymphoid Tissue; Parenteral Nutrition | 2000 |
[Pancreatitis and nutrition. Significance of the gastrointestinal tract and nutrition for septic complications].
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Intestinal Mucosa; Pancreatitis, Acute Necrotizing; Randomized Controlled Trials as Topic; Rats; Survival Rate; Systemic Inflammatory Response Syndrome | 2001 |
Conditionally indispensable amino acids (glutamine, cyst(e)ine, tyrosine, arginine, ornithine, taurine) in enteral feeding and the dipeptide concept.
Topics: Amino Acids, Essential; Animals; Arginine; Cysteine; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Intestinal Mucosa; Ornithine; Taurine; Treatment Outcome; Tyrosine | 2000 |
Potential role of glutamine administration in inflammatory bowel disease.
Topics: Animals; Disease Models, Animal; Glutamine; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Nutrition Disorders; Oxidative Stress; Short Bowel Syndrome | 1999 |
In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.
Topics: Acetates; Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Hyperammonemia; Magnetic Resonance Spectroscopy; Neurons; Nitrogen Isotopes; Rats | 2001 |
Glutamine metabolism in sepsis and infection.
Topics: Animals; Antineoplastic Agents; Bacterial Infections; Biological Transport; Clinical Trials as Topic; Colon; Disease Models, Animal; Forecasting; Glutamine; Humans; Intestine, Small; Liver; Lung; Muscle, Skeletal; Neoplasms; Sepsis; Tumor Cells, Cultured | 2001 |
Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Diarrhea; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Infusions, Intravenous; Neoplasms; Parenteral Nutrition, Total | 2001 |
Nutritional modulation of immune function.
Topics: Animals; Arginine; Cytokines; Dietary Fats, Unsaturated; Disease Models, Animal; Fatty Acids, Omega-3; Glutamine; Humans; Immunity; Inflammation; Nucleotides; Nutritional Physiological Phenomena; T-Lymphocytes | 2001 |
Treatment of short-bowel syndrome.
Topics: Animals; Colon; Dietary Carbohydrates; Disease Models, Animal; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Glutamine; Growth Substances; Humans; Intestine, Small; Peptides; Short Bowel Syndrome | 2001 |
Glutamine in pediatrics: where next?
Topics: Age Factors; Animals; Child; Child, Preschool; Dietary Supplements; Digestive System; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; MEDLINE; Nutritional Requirements; Treatment Outcome | 2002 |
3 trial(s) available for glutamine and Disease Models, Animal
Article | Year |
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Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Combined effects of bovine colostrum and glutamine in diclofenac-induced bacterial translocation in rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Adhesion; Bacterial Translocation; Cattle; Colostrum; Diclofenac; Disease Models, Animal; Enterobacteriaceae; Glutamine; Intestinal Mucosa; Male; Milk; Organ Specificity; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2005 |
Glutamine supplementation in cancer patients.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Carbon Isotopes; Case-Control Studies; Combined Modality Therapy; Dietary Supplements; Disease Models, Animal; Esophageal Neoplasms; Glutamine; Humans; Male; Parenteral Nutrition, Total; Proteins; Rats | 2001 |
427 other study(ies) available for glutamine and Disease Models, Animal
Article | Year |
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Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
LncRNA nuclear-enriched abundant transcript 1 shuttled by prostate cancer cells-secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR-205-5p/runt-related transcription factor 2/splicing factor proline- and glu
Topics: Animals; Bone Neoplasms; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Exosomes; Glutamine; Humans; Male; Mice; MicroRNAs; Osteoblasts; Phenotype; Polypyrimidine Tract-Binding Protein; Proline; Prostatic Neoplasms; RNA Splicing Factors; RNA, Long Noncoding; Tumor Microenvironment | 2021 |
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Animals; Astrocytes; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hippocampus; Male; Metabolome; Mice, Transgenic; Mitochondria; Neurotransmitter Agents; Proteome; Signal Transduction; Synapses | 2021 |
Oral glutamine dipeptide or oral glutamine free amino acid reduces burned injury progression in rats.
Topics: Amino Acids; Animals; Burns; Dipeptides; Disease Models, Animal; Glutamine; Male; Rats; Rats, Wistar | 2021 |
Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model.
Topics: Ammonia; Animals; Disease Models, Animal; Glutaminase; Glutamine; Humans; Hyperammonemia; Liver; Mice; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Urea; Urea Cycle Disorders, Inborn | 2022 |
HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation.
Topics: Animals; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Glutamine; Male; Mice; Mice, Nude; Prostatic Neoplasms; Signal Transduction | 2022 |
Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8
Topics: Amino Acid Transport Systems; Animals; Autism Spectrum Disorder; Disease Models, Animal; Gastrointestinal Microbiome; Glutamine; Mice; Microbiota | 2022 |
Glutamine prevents upregulation of NF-kB signaling and caspase 3 activation in ischaemia/reperfusion-induced testicular damage: An animal model.
Topics: Animals; Antioxidants; Caspase 3; Disease Models, Animal; Glutamine; Humans; Ischemia; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Spermatic Cord Torsion; Testis; Up-Regulation | 2022 |
Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Energy Metabolism; Glutamine; Glycine; Hypercholesterolemia; Hyperlipidemias; Lipids; Metabolomics; Mice; Mice, Inbred C57BL; Nitric Oxide; Receptors, LDL | 2022 |
Synergistic effects of
Topics: Animals; Clomipramine; Curcumin; Depression; Depressive Disorder; Disease Models, Animal; Glutamine; Humans; Infant; Lacticaseibacillus rhamnosus; Mice; Probiotics; Stress, Psychological | 2022 |
Circ_0067717 promotes colorectal cancer cell growth, invasion and glutamine metabolism by serving as a miR-497-5p sponge to upregulate SLC7A5.
Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; MicroRNAs | 2023 |
Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Disease Models, Animal; Glutamine; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Mice; NF-kappa B; Osteoarthritis; Signal Transduction | 2022 |
SARS-CoV-2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes.
Topics: Animals; Astrocytes; Carbon; COVID-19; Cricetinae; Disease Models, Animal; Glucose; Glutamine; Ketoglutaric Acids; Mesocricetus; Pyruvates; SARS-CoV-2 | 2022 |
[
Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Glutamine; Liver Neoplasms; Mice; Mice, Transgenic; Positron-Emission Tomography | 2022 |
Phosphonate analog of 2-oxoglutarate regulates glutamate-glutamine homeostasis and counteracts amyloid beta induced learning and memory deficits in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hippocampus; Homeostasis; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Male; Maze Learning; Memory Disorders; Organophosphonates; Peptide Fragments; Rats; Rats, Wistar | 2022 |
Hsa_circ_0003602 Contributes to the Progression of Colorectal Cancer by Mediating the miR-149-5p/SLC38A1 Axis.
Topics: Amino Acid Transport System A; Animals; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Glutamine; Humans; MicroRNAs | 2023 |
Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model.
Topics: Allantoin; Animals; Biomarkers; Cytidine; Disease Models, Animal; Glucose; Glutamine; Humans; Intermediate Filaments; Multiple Sclerosis; Neurofilament Proteins; Rats | 2022 |
Excretion of excess nitrogen and increased survival by loss of SLC6A19 in a mouse model of ornithine transcarbamylase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Neutral; Ammonia; Animals; Disease Models, Animal; Glutamine; Mice; Mice, Knockout; Nitrogen; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Urea | 2023 |
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Fibrosis; Glutamine; Idiopathic Pulmonary Fibrosis; Lung; Lung Injury; Mice; Mice, Inbred C57BL; RNA, Small Interfering | 2022 |
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
Topics: Ammonia; Animals; Bile Acids and Salts; Bile Ducts; Brain; Choline; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Kynurenine; Liver Diseases; Mice; Microglia; Neuroinflammatory Diseases; Rats; Taurine; Tryptophan | 2022 |
Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer.
Topics: Animals; Disease Models, Animal; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Humans; Male; Mice; Prostatic Neoplasms | 2023 |
Feasibility of [
Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; ErbB Receptors; Feasibility Studies; Glutamates; Glutaminase; Glutamine; Humans; Mice; Positron-Emission Tomography; Proto-Oncogene Proteins p21(ras) | 2023 |
Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Disease Models, Animal; Glutamates; Glutamine; Mice; Mice, Transgenic; Neurons | 2023 |
Mutant Tau protein-induced abnormalities in the Na
Topics: Animals; Astrocytes; Disease Models, Animal; Glutamine; Mice; Mice, Transgenic; Neurons; tau Proteins; Tauopathies | 2023 |
Glutamine Supplementation Preserves Glutamatergic Neuronal Activity in the Infralimbic Cortex, Which Delays the Onset of Mild Cognitive Impairment in 3×Tg-AD Female Mice.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; tau Proteins | 2023 |
Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia.
Topics: Animals; Cachexia; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Glutamine; Histone Code; Histone Methyltransferases; Histones; Humans; Ketoglutaric Acids; Mice; Tumor Microenvironment; TWEAK Receptor | 2023 |
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.
Topics: Animals; Aspartic Acid; Biomarkers; Brain; Corpus Striatum; Disease Models, Animal; Female; Gene Knockout Techniques; Glutamine; Glutathione; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Protein Kinases; Rats; Taurine | 2019 |
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
Topics: Ammonia; Animals; Arginase; Arginine; Codon; Disease Models, Animal; Glutamine; Hyperammonemia; Hyperargininemia; Lipids; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Nanoparticles; RNA, Messenger; Urea | 2019 |
Oral glutamine supplementation attenuates inflammation and oxidative stress-mediated skeletal muscle protein content degradation in immobilized rats: Role of 70 kDa heat shock protein.
Topics: Administration, Oral; Animals; Antioxidants; Creatine Kinase; Dietary Supplements; Disease Models, Animal; Glutamine; Humans; Inflammation; Muscle, Skeletal; NF-kappa B; Oxidative Stress; Proteolysis; Rats; Rats, Wistar | 2019 |
Guhong Injection promotes fracture healing by activating Wnt/beta-catenin signaling pathway in vivo and in vitro.
Topics: Animals; beta Catenin; Biomarkers; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Fracture Healing; Glutamine; Injections, Intraperitoneal; Osteoblasts; Osteogenesis; Plant Extracts; Rats, Sprague-Dawley; Tibia; Tibial Fractures; Wnt Signaling Pathway; Wnt3 Protein | 2019 |
The Novel Glutamine Antagonist Prodrug JHU395 Has Antitumor Activity in Malignant Peripheral Nerve Sheath Tumor.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Glutamine; Humans; Male; Mice; Nerve Sheath Neoplasms; Prodrugs; Xenograft Model Antitumor Assays | 2020 |
Metabolomic changes of blood plasma associated with two phases of rat OIR.
Topics: Animals; Animals, Newborn; Biomarkers; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamine; Hyperoxia; Hypoxia; Metabolome; Metabolomics; Ornithine; Oxidative Stress; Oxygen; Proline; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinopathy of Prematurity | 2020 |
Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Humans; Liver; Male; Medicine, Chinese Traditional; Metabolomics; Protective Agents; Proton Magnetic Resonance Spectroscopy; Rats | 2020 |
Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.
Topics: Adult; Amino Acid Transport System ASC; Animals; Biomarkers; Cell Line; Cicatrix; Disease Models, Animal; Disease Progression; Female; Glutaminase; Glutamine; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Metabolomics; Mice; Middle Aged; Minor Histocompatibility Antigens; Myofibroblasts; Non-alcoholic Fatty Liver Disease; Positron-Emission Tomography | 2020 |
Glutamine protects myocardial ischemia-reperfusion injury in rats through the PI3K/Akt signaling pathway.
Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Glutamine; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Humans; Immunologic Factors; Leishmaniasis, Visceral; Macrophages; Male; Mice, Inbred C57BL; Parasite Load; Phosphorylcholine; T-Lymphocyte Subsets; Treatment Outcome | 2020 |
Glutamine Supplementation Prevents Chronic Stress-Induced Mild Cognitive Impairment.
Topics: Animals; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Glutamine; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Stress, Psychological | 2020 |
Antecedent Dietary Glutamine Supplementation Benefits Modulation of Liver Pyroptosis in Mice with Polymicrobial Sepsis.
Topics: Animals; Anti-Inflammatory Agents; Caspase 1; Caspases, Initiator; Coinfection; Dietary Supplements; Disease Models, Animal; Gene Expression; Glutamine; Immunologic Factors; Inflammation; Liver; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Sepsis | 2020 |
Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease.
Topics: Animals; Aquaporin 4; Brain; Cholestasis; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutamine; Hepatic Encephalopathy; Hippocampus; Immunohistochemistry; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Osmosis; Rats; Rats, Wistar | 2020 |
Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome.
Topics: Animals; Dendrimers; Disease Models, Animal; Female; Glutamic Acid; Glutaminase; Glutamine; Male; Mice; Mice, Knockout; Microglia; Neuroglia; Neuroimmunomodulation; Oxidative Stress; Rett Syndrome | 2020 |
GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis.
Topics: Adult; Aged; Animals; Case-Control Studies; Cell Differentiation; Disease Models, Animal; Female; Glutaminase; Glutamine; Humans; Interleukin-17; Keratinocytes; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Psoriasis; RNA, Messenger; T-Lymphocyte Subsets; Th17 Cells; Young Adult | 2020 |
Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites.
Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Energy Metabolism; Glutamates; Glutamine; Inflammation; Lipids; Lipopolysaccharides; Male; Metabolomics; Mice, Inbred Strains; Molecular Targeted Therapy; Signal Transduction; Swimming | 2020 |
Intravenous Glutamine Administration Improves Glucose Tolerance and Attenuates the Inflammatory Response in Diet-Induced Obese Mice after Sleeve Gastrectomy.
Topics: Adipose Tissue; Animals; Cytokines; Diet, High-Fat; Disease Models, Animal; Gastrectomy; Gluconeogenesis; Glucose Tolerance Test; Glutamine; Inflammation; Inflammation Mediators; Injections, Intravenous; Macrophages; Male; Mice, Inbred C57BL; Obesity | 2020 |
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Carbon Isotopes; Disease Models, Animal; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Hippocampus; Homeostasis; Mice; Mice, Transgenic; Neurotransmitter Agents; Presenilin-1 | 2021 |
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats.
Topics: Animals; Brain; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Methionine Sulfoximine; Pilocarpine; Rats, Sprague-Dawley; Seizures | 2021 |
Glutamine Inhibition Reduces Iatrogenic Laryngotracheal Stenosis.
Topics: Animals; Bleomycin; Collagen; Diazooxonorleucine; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression; Glutamine; Iatrogenic Disease; Injections, Intraperitoneal; Laryngostenosis; Mice; Mucous Membrane; Prospective Studies; Trachea; Tracheal Stenosis | 2021 |
Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
Topics: Adult; Alternaria; Animals; Asthma; Biomarkers; Blood Glucose; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cells, Cultured; Dexamethasone; Disease Models, Animal; Drug Synergism; Female; Glucose Transporter Type 1; Glutaminase; Glutamine; Healthy Volunteers; Humans; Immunosuppressive Agents; Lung; Male; Mice; Middle Aged; Primary Cell Culture; Pyroglyphidae; Th17 Cells; Th2 Cells; Young Adult | 2021 |
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation.
Topics: Acids; Animals; Citric Acid Cycle; Cytokines; Disease Models, Animal; Fructose; Glucose; Glutamine; Glycolysis; Inflammation; Isotope Labeling; Lipopolysaccharides; Macrophages; Metabolic Flux Analysis; Mice, Inbred C57BL; Mitochondria; Monocytes; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Phenotype; T-Lymphocytes | 2021 |
Effect of Intravenous Glutamine on Caspase-12 Expression in the Apoptosis of the Glomerular Epithelial Cells of Male Rats Exposed to Cisplatin.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 12; Cisplatin; Disease Models, Animal; Epithelial Cells; Glutamine; Injections, Intravenous; Kidney Glomerulus; Male; Rats; Rats, Wistar | 2021 |
Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.
Topics: Animals; Carbon-Nitrogen Ligases; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Computational Biology; Disease Models, Animal; Gene Knockdown Techniques; Glutamine; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Mice; Prostatectomy; Prostatic Neoplasms; Purines; Tissue Array Analysis; Up-Regulation; Xenograft Model Antitumor Assays | 2021 |
Dose-Dependent Carbon-Dot-Induced ROS Promote Uveal Melanoma Cell Tumorigenicity via Activation of mTOR Signaling and Glutamine Metabolism.
Topics: Animals; Carbon; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Melanoma; Mice; Mice, Nude; Nanoparticles; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases; Uveal Neoplasms; Zebrafish | 2021 |
Glutamine Supplementation Attenuates the Inflammation Caused by LPS-Induced Acute Lung Injury in Mice by Regulating the TLR4/MAPK Signaling Pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Female; Glutamine; Inflammation Mediators; Lipopolysaccharides; Lung; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Phosphorylation; Pneumonia; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Hepatic cysteine sulphinic acid decarboxylase depletion and defective taurine metabolism in a rat partial nephrectomy model of chronic kidney disease.
Topics: Animals; Carboxy-Lyases; Cysteine Dioxygenase; Dietary Supplements; Disease Models, Animal; Glutamine; Humans; Liver; Male; Muscle, Skeletal; Nephrectomy; Proteinuria; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; RNA, Messenger; Taurine | 2021 |
Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Female; Glucose; Glutamine; Humans; Mice; Mice, Transgenic; Retina | 2022 |
Neuropeptide-S affects cognitive impairment and depression-like behavior on MPTP induced experimental mouse model of Parkinson’s disease
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cognition; Depression; Disease Models, Animal; Dopamine; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Neuropeptides; Neuroprotective Agents; Parkinson Disease, Secondary | 2021 |
The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation in Rats with Ethanol-Induced Liver Damage.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Ethanol; Glutamine; Inflammation; Intestinal Mucosa; Liver; Liver Diseases, Alcoholic; Muscle Proteins; Protein Biosynthesis; Proteolysis; Rats; Rats, Wistar | 2021 |
Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells.
Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Female; Gene Amplification; Gene Expression; Gene Knockdown Techniques; Genes, myc; Glutamine; Glycolysis; Heterografts; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Models, Biological; Small Cell Lung Carcinoma | 2017 |
Effects of early enteral nutrition supplemented with collagen peptides on post-burn inflammatory responses in a mouse model.
Topics: Animals; Burns; Collagen; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Fish Proteins; Fishes; Glutamine; Humans; Interleukin-6; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Peptides; Tumor Necrosis Factor-alpha | 2017 |
Cardiac mGluR1 metabotropic receptors in cardioprotection.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Predisposition to Disease; Glutamine; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phenotype; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Receptors, Metabotropic Glutamate; Signal Transduction; Time Factors; Ventricular Function, Left | 2017 |
Improvement of Antioxidant Defences and Mood Status by Oral GABA Tea Administration in a Mouse Model of Post-Stroke Depression.
Topics: Affect; Animals; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Polyphenols; Reproducibility of Results; Stroke; Tea | 2017 |
The Evaluation of BMAA Inhalation as a Potential Exposure Route Using a rat Model.
Topics: Amino Acids, Diamino; Animals; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Inhalation Exposure; Male; Necrosis; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Tritium | 2018 |
Metabolic Characterization of Myocardial Infarction Using GC-MS-Based Tissue Metabolomics.
Topics: Animals; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Lactic Acid; Male; Metabolomics; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2017 |
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Energy Metabolism; Gene Expression; Glucose; Glutamic Acid; Glutamine; Glycolysis; Heterografts; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lung Neoplasms; Mice; Mitochondria; Models, Biological; NAD; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Riluzole | 2017 |
Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity.
Topics: Animals; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cluster Analysis; Computational Biology; Disease Models, Animal; Energy Metabolism; Gene Expression Profiling; Glioblastoma; Glucose; Glutamine; Heterografts; Humans; Metabolomics; Mice; Mitochondria; Models, Biological; Phenotype | 2017 |
Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.
Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; Disease Models, Animal; Gene Expression; Glutamine; Heterografts; Humans; Immunohistochemistry; Intracellular Space; Mice; Polymers | 2017 |
Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model.
Topics: Animals; Anion Transport Proteins; Antigens, Polyomavirus Transforming; Blotting, Western; Cell Line; Cell Proliferation; Corneal Dystrophies, Hereditary; Disease Models, Animal; Endothelium, Corneal; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Ion Transport; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Real-Time Polymerase Chain Reaction; Symporters | 2017 |
Glutamine prevents oxidative stress in a model of portal hypertension.
Topics: Animals; Antioxidants; Disease Models, Animal; Glutamine; Glutathione Peroxidase; Hypertension, Portal; Immunohistochemistry; Intestinal Mucosa; Ligation; Lipid Peroxidation; Liver; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Portal Vein; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2017 |
(S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Cerebrovascular Circulation; Cognitive Dysfunction; Dementia, Vascular; Disease Models, Animal; Glutamic Acid; Glutamine; Male; Neurons; Neuroprotective Agents; Nootropic Agents; Pyrrolidines; Rats; Rats, Wistar; Spatial Learning; Spatial Memory; Stereoisomerism; White Matter | 2017 |
Influence of an ω3-fatty acid-enriched enteral diet with and without added glutamine on the metabolic response to injury in a rat model of prolonged acute catabolism.
Topics: Acute Disease; Animals; Diet; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Male; Metabolism; Nitrogen; Rats; Rats, Sprague-Dawley; Time; Weight Gain; Wounds and Injuries | 2017 |
Does l-glutamine-supplemented diet extenuate NO-mediated damage on myenteric plexus of Walker 256 tumor-bearing rats?
Topics: Animals; Antioxidants; Cachexia; Carcinoma 256, Walker; Dietary Supplements; Disease Models, Animal; Glutamine; Ileum; Jejunum; Male; Myenteric Plexus; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; tert-Butylhydroperoxide; Tumor Burden | 2017 |
TAp73 is a marker of glutamine addiction in medulloblastoma.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Heterografts; Humans; Medulloblastoma; Mice; Mitochondria; Nuclear Proteins; Survival Analysis; TOR Serine-Threonine Kinases; Treatment Outcome; Tumor Cells, Cultured; Tumor Protein p73 | 2017 |
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
Topics: Actins; Animals; Benzeneacetamides; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Enzyme Activation; Fibronectins; Glutaminase; Glutamine; Humans; Hydroxylation; Ketoglutaric Acids; Mice; Mice, Inbred C57BL; Myofibroblasts; Proline; Pulmonary Fibrosis; RNA Interference; RNA, Small Interfering; Sulfides; Thiadiazoles; TOR Serine-Threonine Kinases | 2018 |
Altered mGluR5 binding potential and glutamine concentration in the 6-OHDA rat model of acute Parkinson's disease and levodopa-induced dyskinesia.
Topics: Acute Disease; Animals; Cerebral Cortex; Disease Models, Animal; Dyskinesias; Female; Glutamine; Levodopa; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Putamen; Rats, Wistar; Receptor, Metabotropic Glutamate 5 | 2018 |
[Metabonomic analysis of the urine from rat model with abnormal sapra syndrome].
Topics: Amino Acids; Animals; Citric Acid; Creatine; Disease Models, Animal; Energy Metabolism; Glutamine; Glycoproteins; Isoleucine; Leucine; Metabolomics; Phenylalanine; Rats; Rats, Wistar; Syndrome | 2017 |
Topics: Animals; Cell Proliferation; Collagen Diseases; Disease Models, Animal; Energy Metabolism; Fatty Acids; Fibroblasts; Glucose; Glutamine; Glycolysis; Humans; Immune System; Mice; Oxidation-Reduction; Synovial Membrane | 2017 |
Glutamine reduces myocardial cell apoptosis in a rat model of sepsis by promoting expression of heat shock protein 90.
Topics: Animals; Apoptosis; Caspases; Disease Models, Animal; Glutamine; HSP90 Heat-Shock Proteins; Myocytes, Cardiac; Rats, Wistar; Sepsis | 2017 |
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Transport System ASC; Animals; Biomarkers, Tumor; Breast Neoplasms; Disease Models, Animal; DNA-Binding Proteins; Ephrin-A2; Female; Glutaminase; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Minor Histocompatibility Antigens; Muscle Proteins; Phosphoproteins; Receptor, EphA2; TEA Domain Transcription Factors; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; Tumor Cells, Cultured; YAP-Signaling Proteins | 2017 |
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Disease Models, Animal; Glutamine; HCT116 Cells; Humans; Mice; Minor Histocompatibility Antigens; Neoplasms; Oxidative Stress; Signal Transduction; Small Molecule Libraries | 2018 |
Effect of parenteral glutamine supplementation combined with enteral nutrition on Hsp90 expression and Peyer's patch apoptosis in severely burned rats.
Topics: Animals; Apoptosis; Burns; Cytokines; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; HSP90 Heat-Shock Proteins; Intestinal Mucosa; Male; Parenteral Nutrition; Peyer's Patches; Rats; Rats, Sprague-Dawley | 2018 |
Enteral nutrition combined with glutamine promotes recovery after ileal pouch-anal anastomosis in rats.
Topics: Anastomosis, Surgical; Animals; Body Weight; Colitis, Ulcerative; Colonic Pouches; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Ileum; Intestinal Mucosa; Male; Microsurgery; Nutritional Status; Occludin; Postoperative Care; Postoperative Complications; Proctocolectomy, Restorative; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms | 2018 |
Biochemical markers of striatal desensitization in cortical-limbic hyperglutamatergic TS- & OCD-like transgenic mice.
Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Glutamine; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Obsessive-Compulsive Disorder; Tourette Syndrome | 2018 |
GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way.
Topics: Animals; Cell Line; Chloroquine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; G-Protein-Coupled Receptor Kinase 2; Ganglia, Spinal; Gene Knockdown Techniques; Glutamine; Histamine; Humans; Injections, Subcutaneous; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Pruritus; Rats; RNA, Small Interfering | 2018 |
NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host-Gut Microbiota Interactions during Inflammatory Bowel Disease.
Topics: Animals; Cells, Cultured; Clostridiales; Colitis; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Epithelial Cells; Gastrointestinal Microbiome; Glutamine; Humans; Immunity, Innate; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Veillonella | 2018 |
The effect of FASN inhibition on the growth and metabolism of a cisplatin-resistant ovarian carcinoma model.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Fatty Acid Synthase, Type I; Fatty Acids; Female; Glutamine; Humans; Mice; Orlistat; Ovarian Neoplasms; Oxidation-Reduction | 2018 |
Cerebral Multimodal Monitoring in Sepsis: An Experimental Study.
Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Glucose; Glutamine; Hemodynamics; Intracranial Pressure; Male; Microdialysis; Sepsis; Swine | 2019 |
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Topics: Adaptation, Physiological; Alanine; Animals; Disease Models, Animal; DNA, Mitochondrial; Energy Metabolism; Glutamine; HeLa Cells; Humans; Ketoglutaric Acids; Male; Mice; Mitochondria; Mitochondrial Myopathies; Mutation; Oxidative Phosphorylation | 2018 |
MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.
Topics: Amino Acid Substitution; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; Disease Models, Animal; Drug Design; Glutamine; GTP Phosphohydrolases; Humans; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Oligopeptides; Phosphorylation; Protein Kinases; Sciatic Nerve; Small Molecule Libraries; Threonine | 2018 |
Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism.
Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; Brain; Disease Models, Animal; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Mice, Transgenic; Neurotransmitter Agents; Proteome | 2018 |
Early Activation of Astrocytes does not Affect Amyloid Plaque Load in an Animal Model of Alzheimer's Disease.
Topics: Aldehyde Dehydrogenase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Brain; Calcium-Binding Proteins; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamine; Green Fluorescent Proteins; Humans; Ki-67 Antigen; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Nerve Tissue Proteins; Oxidoreductases Acting on CH-NH Group Donors | 2018 |
Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii.
Topics: Adenosine Triphosphate; Animals; Brain; Carbon; Disease Models, Animal; Gene Deletion; Gluconeogenesis; Glutamine; Glycolysis; Hexokinase; Metabolic Flux Analysis; Mice; Oxidative Phosphorylation; Phosphoenolpyruvate Carboxykinase (ATP); Toxoplasma; Toxoplasmosis; Virulence | 2018 |
Combined Enteral and Parenteral Glutamine Supplementation in Endotoxemic Swine: Effects on Portal and Systemic Circulation Levels.
Topics: Administration, Intravenous; Animals; Dietary Supplements; Disease Models, Animal; Drug Administration Routes; Endotoxemia; Escherichia coli; Escherichia coli Infections; Female; Glutamine; Greece; Portal System; Swine; Swine Diseases | 2018 |
GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay.
Topics: Adolescent; Animals; Brain; Cataract; Child, Preschool; Developmental Disabilities; Disease Models, Animal; Female; Fibroblasts; Gain of Function Mutation; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; HEK293 Cells; Humans; Male; Oxidative Stress; Reactive Oxygen Species; Zebrafish | 2019 |
Basolateral presence of the proinflammatory cytokine tumor necrosis factor -α and secretions from adipocytes and macrophages reduce intestinal sugar transport.
Topics: Adipocytes; Animals; Caco-2 Cells; Culture Media, Conditioned; Disease Models, Animal; Down-Regulation; Glutamine; Humans; Intestinal Absorption; Intestinal Mucosa; Macrophages; Male; Methylglucosides; Mice, Inbred C57BL; Obesity; Paracrine Communication; Secretory Pathway; Signal Transduction; Sodium-Glucose Transporter 1; THP-1 Cells; Tumor Necrosis Factor-alpha | 2019 |
Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Bacterial Agents; Ceftriaxone; Cognition; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Glutamine; Hippocampus; Maze Learning; Mice; Mice, Transgenic; Presenilin-1; Up-Regulation | 2018 |
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Memantine; Motor Activity; Rats; Rats, Wistar; Schizophrenia; Stress, Psychological; Sucrose; Taurine | 2019 |
MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice.
Topics: Adult; Animals; Antimalarials; Biomarkers; Blood-Brain Barrier; Brain; Brain Edema; Child; Diazooxonorleucine; Disease Models, Animal; Disease Progression; Female; Glutamine; Humans; Magnetic Resonance Imaging; Malaria, Cerebral; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Plasmodium falciparum | 2018 |
Glutamine protects against oxidative stress injury through inhibiting the activation of PI3K/Akt signaling pathway in parkinsonian cell model.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Cell Culture Techniques; Disease Models, Animal; Glutamine; Oxidative Stress; Parkinson Disease; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Rats | 2019 |
Sheathless CE-MS based metabolic profiling of kidney tissue section samples from a mouse model of Polycystic Kidney Disease.
Topics: Animals; Betaine; Carnitine; Creatine; Creatinine; Disease Models, Animal; Electrophoresis, Capillary; Glutamine; Kidney; Mass Spectrometry; Metabolomics; Mice; Multivariate Analysis; Polycystic Kidney Diseases | 2019 |
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
Topics: Acetates; Animals; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Child, Preschool; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Glutamine; Hepatocytes; Humans; Infant; Liver Neoplasms; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenols; Retrospective Studies; Sirolimus; TOR Serine-Threonine Kinases; Transfection; Wnt Signaling Pathway | 2019 |
TEAD1 (TEA Domain Transcription Factor 1) Promotes Smooth Muscle Cell Proliferation Through Upregulating SLC1A5 (Solute Carrier Family 1 Member 5)-Mediated Glutamine Uptake.
Topics: Amino Acid Transport System ASC; Animals; Biological Transport; Cell Proliferation; Coronary Artery Disease; Disease Models, Animal; DNA-Binding Proteins; Glutamine; Humans; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Minor Histocompatibility Antigens; Myocytes, Smooth Muscle; Neointima; RNA Interference; Signal Transduction; TEA Domain Transcription Factors; Transcription Factors; Transcriptional Activation; Up-Regulation | 2019 |
Inhibition of glutamine metabolism accelerates resolution of acute lung injury.
Topics: Acute Lung Injury; Amphiregulin; Animals; Anti-Inflammatory Agents; Antimetabolites; Cytokines; Diazooxonorleucine; Disease Models, Animal; Glutamine; Inflammation Mediators; Lipopolysaccharides; Lung; Macrophages; Mice, Inbred C57BL; Neutrophil Infiltration; Pneumonia; Time Factors | 2019 |
Taurine transporter (TauT) deficiency impairs ammonia detoxification in mouse liver.
Topics: Ammonia; Animals; Deficiency Diseases; Disease Models, Animal; GABA Plasma Membrane Transport Proteins; Gene Knockdown Techniques; Glutamate-Ammonia Ligase; Glutamine; Glycoproteins; Hepatocytes; Hyperammonemia; Inactivation, Metabolic; Kinetics; Liver; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Oxidative Stress; Perfusion; Urea | 2019 |
In-solution behavior and protective potential of asparagine synthetase A from Trypanosoma cruzi.
Topics: Ammonia; Animals; Asparagine; Aspartate-Ammonia Ligase; Chagas Disease; Chromatography, Liquid; Circular Dichroism; Disease Models, Animal; Dynamic Light Scattering; Glutamine; Mice, Inbred BALB C; Parasitemia; Protein Conformation; Protein Folding; Protozoan Vaccines; Recombinant Proteins; Trypanosoma cruzi; Vaccines, Synthetic | 2019 |
Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Energy Metabolism; Glutamine; Humans; Leukemia; Mice; Mice, Transgenic; Molecular Targeted Therapy; Oxidation-Reduction; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2019 |
Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice.
Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Glutamic Acid; Glutamine; Male; Mice, Inbred Strains; Stress, Psychological | 2019 |
QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis.
Topics: Animals; Cell Proliferation; Dihydropteridine Reductase; Disease Models, Animal; Gene Knockdown Techniques; Glutamine; Humans; Melanins; Neuroglia; Phenylketonurias; Zebrafish; Zebrafish Proteins | 2019 |
Glutamine Therapy Reduces Inflammation and Extracellular Trap Release in Experimental Acute Respiratory Distress Syndrome of Pulmonary Origin.
Topics: Animals; Disease Models, Animal; DNA; Endotoxins; Extracellular Traps; Female; Glutamine; Glutathione Peroxidase; Glutathione Reductase; Inflammation; Interferon-gamma; Interleukin-10; Leukocyte Count; Lung; Male; Mice, Inbred BALB C; Peroxidase; Pneumonia; Pulmonary Alveoli; Reactive Oxygen Species; Respiratory Distress Syndrome | 2019 |
Clinical and Pathological Benefit of Twendee X in Alzheimer's Disease Transgenic Mice with Chronic Cerebral Hypoperfusion.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Behavior, Animal; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Cognition; Cystine; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neuroprotective Agents; Oxidative Stress; Plaque, Amyloid | 2019 |
Effects of dietary glutamine supplementation on immune cell polarization and muscle regeneration in diabetic mice with limb ischemia.
Topics: Animals; Cell Polarity; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Disease Models, Animal; Glutamine; Hindlimb; Immunity; Ischemia; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Regeneration | 2020 |
Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer.
Topics: Animals; Biomarkers; Breast Neoplasms; Cell Line, Tumor; Computational Biology; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Profiling; Glutaminase; Glutamine; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Models, Biological; Proline; Xenograft Model Antitumor Assays | 2019 |
Labeling Cancer Stem Cells with
Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell Hypoxia; Cell Line, Tumor; Cell Separation; Disease Models, Animal; Glucose; Glutamine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isotope Labeling; Metabolic Flux Analysis; Metabolic Networks and Pathways; Metabolomics; Mice; Neoplastic Stem Cells; Pancreatic Neoplasms; Single-Cell Analysis | 2019 |
Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma.
Topics: Animals; Body Weight; Brain; Brain Neoplasms; Caloric Restriction; Cell Line, Tumor; Cell Proliferation; Diazooxonorleucine; Diet, Ketogenic; Disease Models, Animal; Female; Fermentation; Glioblastoma; Glucose; Glutamine; Humans; Immunohistochemistry; Ketone Bodies; Ketones; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation | 2019 |
A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice.
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Diet; Disease Models, Animal; Glutamine; Male; Mice, Inbred C57BL; Restraint, Physical; Stress, Psychological | 2019 |
Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy.
Topics: Ammonium Compounds; Animals; Ascorbic Acid; Astrocytes; Chronic Disease; Creatine; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hippocampus; Male; Oxidative Stress; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Wistar | 2019 |
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
Topics: Animals; Biological Transport; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Male; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Binding; Pyruvic Acid; Receptors, Androgen; Signal Transduction | 2019 |
Effect of Oral Branched-Chain Amino Acids and Glutamine Supplementation on Skeletal Muscle Atrophy After Total Gastrectomy in Rat Model.
Topics: Amino Acids, Branched-Chain; Animals; Dietary Supplements; Disease Models, Animal; Gastrectomy; Glutamine; Male; Rats, Wistar; Sarcopenia | 2019 |
Twendee X Ameliorates Phosphorylated Tau, α-Synuclein and Neurovascular Dysfunction in Alzheimer's Disease Transgenic Mice With Chronic Cerebral Hypoperfusion.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Ascorbic Acid; Brain; Cerebrovascular Disorders; Cystine; Dietary Supplements; Disease Models, Animal; Female; Genetic Predisposition to Disease; Glutamine; Male; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurovascular Coupling; Phenotype; Phosphorylation; tau Proteins | 2019 |
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glutamine; Glycolysis; Hexosamines; Humans; Hypoxia; Lactic Acid; Male; Metabolic Networks and Pathways; Mice; Mice, Nude; Mice, Transgenic; Models, Biological; Pancreatic Neoplasms; Transplantation, Heterologous | 2013 |
Effect of glutamine on apoptosis of intestinal epithelial cells of severe acute pancreatitis rats receiving nutritional support in different ways.
Topics: Acute Disease; Animals; Apoptosis; Combined Modality Therapy; Cytokines; Disease Models, Animal; Enteral Nutrition; Feeding Methods; Glutamine; Intestinal Mucosa; Male; Pancreas; Pancreatitis; Parenteral Nutrition; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 2013 |
The combined effects of glutamine and growth hormone on intestinal anastomosis in the rat intra-abdominal sepsis model.
Topics: Administration, Oral; Anastomosis, Surgical; Animals; Disease Models, Animal; Drug Therapy, Combination; Glutamine; Growth Hormone; Hydroxyproline; Injections, Subcutaneous; Intestinal Mucosa; Intestines; Intraabdominal Infections; Male; Postoperative Complications; Rats; Rats, Sprague-Dawley; Sepsis; Wound Healing | 2013 |
The effect of glutamine on cerebral ischaemic injury after cardiac arrest.
Topics: Animals; Blotting, Western; Brain; Brain Ischemia; Cardiopulmonary Resuscitation; Disease Models, Animal; Glutamine; Heart Arrest; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Statistics, Nonparametric; Tissue and Organ Harvesting | 2013 |
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Topics: Amino Acids; Animals; Biological Transport; Carbon; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Glutamine; Mice; Mice, Nude; NIH 3T3 Cells; Oncogene Protein p21(ras); Pancreatic Neoplasms; Pinocytosis; Proteolysis | 2013 |
In vivo neurometabolic profiling to characterize the effects of social isolation and ketamine-induced NMDA antagonism: a rodent study at 7.0 T.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Ketamine; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Social Isolation | 2014 |
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Disease Models, Animal; Glucose; Glutamine; Male; Metformin; Mice; Mice, Transgenic; Oxidation-Reduction; Prostatic Neoplasms | 2013 |
Effects of glutamine on wound healing.
Topics: Animals; Disease Models, Animal; Female; Glutamine; Prognosis; Rats; Rats, Sprague-Dawley; Wound Healing; Wounds and Injuries | 2015 |
Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Diazooxonorleucine; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Glucose; Glutamine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Models, Biological; Oxidation-Reduction; Proto-Oncogene Proteins c-myc; Rats | 2013 |
Dietary L-glutamine supplementation increases Pasteurella multocida burden and the expression of its major virulence factors in mice.
Topics: Animals; Antioxidants; Cytokines; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Glutamine; Inflammation; Mice; Mice, Inbred Strains; Organ Specificity; Pasteurella; Pasteurella Infections; Toll-Like Receptors; Virulence Factors | 2013 |
Antioxidant properties of glutamine and its role in VEGF-Akt pathways in portal hypertension gastropathy.
Topics: Animals; Antioxidants; Disease Models, Animal; Esophageal and Gastric Varices; Glutamine; Glutathione; Hypertension, Portal; Male; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Stomach; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine; Vascular Endothelial Growth Factor A | 2013 |
Parkinson's disease: in vivo metabolic changes in the frontal and parietal cortices in 6-OHDA treated rats during different periods.
Topics: Animals; Aspartic Acid; Choline; Corpus Striatum; Creatine; Disease Models, Animal; Frontal Lobe; Functional Laterality; Functional Neuroimaging; Glutamates; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Motor Activity; Oxidopamine; Parietal Lobe; Parkinson Disease, Secondary; Rats; Substantia Nigra; Time Factors | 2014 |
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors.
Topics: Adenocarcinoma; Adenoma; Adenoma, Oxyphilic; Animals; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Deletion; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Lung Neoplasms; Mice; Microtubule-Associated Proteins; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins B-raf; Tumor Suppressor Protein p53 | 2013 |
Effects of enteral nutrition on the barrier function of the intestinal mucosa and dopamine receptor expression in rats with traumatic brain injury.
Topics: Animals; Bacterial Translocation; Brain Injuries; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Mucosa; Male; Probiotics; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger | 2015 |
Glutamine supplementation, but not combined glutamine and arginine supplementation, improves gut barrier function during chemotherapy-induced intestinal mucositis in rats.
Topics: Animals; Arginine; Dietary Supplements; Disease Models, Animal; Gastrointestinal Tract; Glutamine; Immunohistochemistry; Intestines; Male; Methotrexate; Mucositis; NF-kappa B; Occludin; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2014 |
The protective effect of VSL#3 on intestinal permeability in a rat model of alcoholic intestinal injury.
Topics: Animals; Bifidobacterium; Central Nervous System Depressants; Disease Models, Animal; Endotoxins; Ethanol; Glutamine; Intestinal Mucosa; Intestines; Lactobacillus; Liver Diseases, Alcoholic; Male; Microscopy, Electron, Transmission; Occludin; Permeability; Probiotics; Rats; Streptococcus thermophilus; Tight Junctions; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2013 |
R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Flurbiprofen; Glutamic Acid; Glutamine; Hippocampus; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Maze Learning; Mice; Mice, Transgenic; tau Proteins | 2013 |
Cancer usurps skeletal muscle as an energy repository.
Topics: Amino Acids; Animals; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Energy Metabolism; Glutamine; Heterografts; HMGB1 Protein; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mitochondria, Muscle; Muscle, Skeletal; Recombinant Proteins | 2014 |
Anticonvulsant, anxiolytic and hypnotic effects of aqueous bulb extract of Crinum glaucum A. chev (Amaryllidaceae): role of GABAergic and nitrergic systems.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Crinum; Disease Models, Animal; Enzyme Inhibitors; Female; GABA-A Receptor Antagonists; GABAergic Neurons; Glutamine; Hypnotics and Sedatives; Male; Mice; Motor Activity; Nitrergic Neurons; Nitric Oxide Synthase; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Seizures; Sleep | 2013 |
Neuronal and astrocytic metabolism in a transgenic rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Astrocytes; Brain; Citric Acid Cycle; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Neurons; Pyruvic Acid; Rats; Rats, Transgenic; Rats, Wistar | 2014 |
Validation of the gastroschisis experimental model and the influence of the mother's diet enriched with glutamine in the fetal morphology.
Topics: Animals; Body Weight; Dietary Supplements; Disease Models, Animal; Female; Fetal Development; Fetus; Gastroschisis; Glutamine; Intestines; Organ Size; Pregnancy; Rats, Wistar; Reproducibility of Results | 2014 |
L-glutamine supplementation prevents the development of experimental diabetic cardiomyopathy in streptozotocin-nicotinamide induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dietary Supplements; Disease Models, Animal; Electroencephalography; Glutamine; Hemodynamics; Male; Myocardium; Rats | 2014 |
Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice.
Topics: Animals; Antineoplastic Agents; Aziridines; Disease Models, Animal; Genetic Therapy; Glutamine; Lung Neoplasms; Mice; Neoplasm Metastasis; Nitroreductases; Optical Imaging; Organometallic Compounds; Prodrugs; Radiography; Thymidine Kinase; Treatment Outcome; Triple Negative Breast Neoplasms | 2014 |
Glutamine protects the small intestinal mucosa in anticancer drug-induced rat enteritis model.
Topics: Administration, Oral; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agents; Dietary Fiber; Disease Models, Animal; Enteritis; Fluorouracil; Glutamine; Immunoglobulin A; Intestinal Mucosa; Jejunum; Male; Oligosaccharides; Rats; Rats, Sprague-Dawley | 2014 |
Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment.
Topics: Animals; Bacteria; Cytokines; Cytoprotection; Disease Models, Animal; Glutamine; Hypoxia; Inflammation Mediators; Intestinal Mucosa; Intestines; Male; Malondialdehyde; Myeloid Differentiation Factor 88; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Time Factors; Toll-Like Receptor 4; Transcription Factor RelA | 2014 |
Preconditioning with glutamine protects against ischemia/reperfusion-induced hepatic injury in rats with obstructive jaundice.
Topics: Animals; Apoptosis; Disease Models, Animal; Down-Regulation; Glutamine; Glutathione; Hepatocytes; Interleukin-1beta; Jaundice, Obstructive; Liver; Male; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo.
Topics: Animals; Astrocytes; Brain; Citric Acid Cycle; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Glutamine; Kainic Acid; Lactates; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL | 2014 |
ACVR1 p.Q207E causes classic fibrodysplasia ossificans progressiva and is functionally distinct from the engineered constitutively active ACVR1 p.Q207D variant.
Topics: Activin Receptors, Type I; Amino Acid Sequence; Animals; Chickens; Child; Disease Models, Animal; Genetic Variation; Glutamic Acid; Glutamine; Hindlimb; Humans; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Muscle, Skeletal; Myositis Ossificans; NIH 3T3 Cells; Point Mutation; Polymorphism, Single Nucleotide; Sequence Alignment | 2014 |
Glutamine supplementation attenuates expressions of adhesion molecules and chemokine receptors on T cells in a murine model of acute colitis.
Topics: Acute Disease; Administration, Oral; Animals; Body Weight; Cell Adhesion Molecules; Cell Movement; Colitis; Colon; Dietary Supplements; Disease Models, Animal; Glutamine; Heparin; Intestinal Mucosa; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Polysaccharides; Receptors, CCR; Receptors, Chemokine; T-Lymphocytes | 2014 |
Glutamine downregulates TLR-2 and TLR-4 expression and protects intestinal tract in preterm neonatal rats with necrotizing enterocolitis.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Down-Regulation; Enterocolitis, Necrotizing; Female; Glutamine; Intestinal Mucosa; Intestines; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2014 |
In vivo 1H MRS study in microlitre voxels in the hippocampus of a mouse model of Down syndrome at 11.7 T.
Topics: Animals; Brain Chemistry; Disease Models, Animal; Dominance, Cerebral; Down Syndrome; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neuroimaging; Nuclear Magnetic Resonance, Biomolecular; Proton Magnetic Resonance Spectroscopy | 2014 |
Glutamine attenuates acute lung injury caused by acid aspiration.
Topics: Acute Lung Injury; Administration, Intravenous; Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL1; Disease Models, Animal; Glutamine; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Pneumonia, Aspiration; Positive-Pressure Respiration; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Tidal Volume; Tumor Necrosis Factor-alpha; Ventilator-Induced Lung Injury | 2014 |
Effects of glutamine alone on the acute necrotizing pancreatitis in rats.
Topics: Alanine Transaminase; Amylases; Animals; Detergents; Disease Models, Animal; Glutamine; Glycodeoxycholic Acid; Interleukin-6; L-Lactate Dehydrogenase; Male; Microcirculation; Pancreas; Pancreatitis, Acute Necrotizing; Rats, Sprague-Dawley; Sodium Chloride; Treatment Outcome | 2015 |
Glutamine prevents oxidative stress in a model of mesenteric ischemia and reperfusion.
Topics: Animals; Antioxidants; Biomarkers; Disease Models, Animal; Glutamine; Interleukin-6; Intestinal Mucosa; Intestines; Lipid Peroxidation; Lung; Lung Injury; Male; NF-kappa B; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Respiratory Mucosa; Superoxide Dismutase; Time Factors | 2014 |
Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia.
Topics: Animals; Biomarkers; Brain Ischemia; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Time Factors | 2014 |
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes.
Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature | 2014 |
¹H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; GABAergic Neurons; Glioblastoma; Glutamine; Humans; Metabolome; Mice; Proton Magnetic Resonance Spectroscopy | 2015 |
Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Electron Transport Complex I; Gene Expression; Glucose Transporter Type 4; Glutamine; Humans; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mitochondria; Multiple Myeloma; Multiprotein Complexes; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Invasiveness; Oxygen Consumption; Proto-Oncogene Proteins c-akt; Ritonavir; TOR Serine-Threonine Kinases; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.
Topics: Alphavirus Infections; Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Diazooxonorleucine; Disease Models, Animal; Encephalitis, Viral; Enzyme-Linked Immunosorbent Assay; Glutamine; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Activity; Sindbis Virus | 2015 |
¹H- and ¹³C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain; Carbon-13 Magnetic Resonance Spectroscopy; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Male; Mice, Transgenic; Mutation; Peptide Fragments; Phosphorylcholine; Proton Magnetic Resonance Spectroscopy | 2015 |
Parenteral glutamine supplementation in combination with enteral nutrition improves intestinal immunity in septic rats.
Topics: Animals; Apoptosis; Body Weight; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Immunity, Mucosal; Immunoglobulin A; Intestinal Mucosa; Lymphocytes; Male; Parenteral Nutrition; Peyer's Patches; Plasma Cells; Rats; Rats, Sprague-Dawley; Sepsis; Treatment Outcome | 2015 |
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.
Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Genes, myc; Genes, ras; Glutaminase; Glutamine; Humans; Kidney Neoplasms; Lipid Metabolism; Mice; Mice, SCID; Mice, Transgenic; RNA, Messenger; RNA, Neoplasm; Spectrometry, Mass, Electrospray Ionization; Sulfides; Thiadiazoles; Up-Regulation | 2015 |
Glutamine Administration After Sublethal Lower Limb Ischemia Reduces Inflammatory Reaction and Offers Organ Protection in Ischemia/Reperfusion Injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Hindlimb; Inflammation; Lung; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Neutrophils; Reperfusion Injury | 2016 |
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.
Topics: Animals; Cells, Cultured; Creatine Kinase; Disease Models, Animal; DNA Mutational Analysis; Enzyme Inhibitors; Female; Glutaminase; Glutamine; Glutarates; Humans; Infant; Infant, Newborn; Male; Metabolomics; Mice; Models, Genetic; Polycystic Kidney Diseases | 2015 |
Glutamine ameliorates intestinal ischemia-reperfusion Injury in rats by activating the Nrf2/Are signaling pathway.
Topics: Animals; Antioxidant Response Elements; Binding Sites; Caspase 3; Cytoprotection; Disease Models, Animal; Gene Expression Regulation; Glutamine; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Jejunal Diseases; Jejunum; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Permeability; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Reperfusion Injury; Signal Transduction; Superoxide Dismutase | 2015 |
System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.
Topics: Amino Acid Transport System A; Animals; Antibodies; Arthritis, Experimental; Cell Line, Transformed; Cell Proliferation; Collagen; Disease Models, Animal; Glutamine; Lymphocyte Activation; Male; Mice; Mice, Knockout; Nitric Oxide; Sodium; T-Lymphocytes; Up-Regulation | 2015 |
Neuroprotective effects of Aceglutamide on motor function in a rat model of cerebral ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cell Death; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Mesencephalon; Movement Disorders; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Rats, Sprague-Dawley; Substantia Nigra; Treatment Outcome | 2015 |
Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance.
Topics: Administration, Oral; Animals; Diet, High-Fat; Disease Models, Animal; Glutamine; Insulin Resistance; Mice | 2016 |
Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease.
Topics: Animals; Bortezomib; Cell Line; Corpus Striatum; Disease Models, Animal; Glutamine; Huntingtin Protein; Huntington Disease; Mice; Nerve Tissue Proteins; Nuclear Proteins; Oligopeptides; Peptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteomics | 2015 |
Involvement of glutamatergic neurotransmission in the antidepressant-like effect of zinc in the chronic unpredictable stress model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blotting, Western; Chlorides; Depression; Disease Models, Animal; Female; Fluoxetine; Glutamine; Hippocampus; Mice; Stress, Psychological; Synaptic Transmission; Zinc Compounds | 2016 |
Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model.
Topics: Alcohol Drinking; Amino Acid Transport Systems, Acidic; Animals; Biogenic Monoamines; Disease Models, Animal; Dopamine; Ethanol; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Serotonin; Substance Withdrawal Syndrome | 2016 |
Mixture of Arginine, Glutamine, and β-hydroxy-β-methyl Butyrate Enhances the Healing of Ischemic Wounds in Rats.
Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glutamine; Hydroxyproline; Ischemia; Rats; Rats, Wistar; Valerates; Wound Healing | 2017 |
ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Respiration; Cytoprotection; Disease Models, Animal; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Female; Glucose; Glutamine; Humans; Imidazoles; Lactates; Mice, Inbred NOD; Mice, SCID; Mitochondria; Models, Biological; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolines; Reactive Oxygen Species; Receptors, Estrogen; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2016 |
Neurochemical Changes Associated with Stress-Induced Sleep Disturbance in Rats: In Vivo and In Vitro Measurements.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamine; Magnetic Resonance Imaging; Male; Radiography; Rats; Rats, Sprague-Dawley; Serotonin; Sleep Wake Disorders; Stress, Psychological; Tandem Mass Spectrometry | 2016 |
Evaluation of a new concept of immune-enhancing diet in a model of head-injured rat with infectious complications: A proof of concept study.
Topics: Amino Acids; Animals; Antioxidants; Craniocerebral Trauma; Diet Therapy; Disease Models, Animal; Enteral Nutrition; Escherichia coli Infections; Glutamine; Humans; Immunity; Infection Control; Infections; Nutritional Requirements; Proof of Concept Study; Rats | 2016 |
Involvement of glutamatergic N-methyl-d-aspartate receptors in the expression of increased head-dipping behaviors in the hole-board tests of olfactory bulbectomized mice.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Frontal Lobe; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Head Movements; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Olfactory Bulb; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2016 |
Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease.
Topics: Animals; Astrocytes; Brain; Cyclophilin A; Disease Models, Animal; DNA-Binding Proteins; Dopamine and cAMP-Regulated Phosphoprotein 32; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Locomotion; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurons; Nuclear Proteins | 2016 |
Desired and side effects of the supplementation with l-glutamine and l-glutathione in enteric glia of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Glutamine; Glutathione; Male; Myenteric Plexus; Neuroglia; Neurons; Rats, Wistar | 2016 |
The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.
Topics: Alzheimer Disease; Animals; Ataxia Telangiectasia; Blood Glucose; Cell Cycle Proteins; Disease Models, Animal; DNA-Binding Proteins; Glutamine; Mice, Knockout; Neurons; Neuroprotective Agents | 2016 |
Targeting immunoproteasome and glutamine supplementation prevent intestinal hyperpermeability.
Topics: Animals; Avoidance Learning; Colon; Dietary Supplements; Disease Models, Animal; Glutamine; Inflammation; Intestinal Mucosa; Intestines; Male; Mice, Inbred C57BL; Occludin; Permeability; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Trinitrobenzenesulfonic Acid | 2017 |
Intravenous Glutamine Administration Modulates TNF-α/IL-10 Ratio and Attenuates NFkB Phosphorylation in a Protein Malnutrition Model.
Topics: Animals; Disease Models, Animal; Glutamine; Interleukin-10; Mice; Mice, Inbred BALB C; NF-kappa B; Peritoneum; Phosphorylation; Protein-Energy Malnutrition; Tumor Necrosis Factor-alpha | 2016 |
Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock.
Topics: Animals; Brain; Disease Models, Animal; Glutamine; Liver; Lung; Myocardium; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Succinic Acid | 2016 |
Protective effect of L-glutamine against diabetes-induced nephropathy in experimental animal: Role of KIM-1, NGAL, TGF-β1, and collagen-1.
Topics: Acute-Phase Proteins; Animals; Cell Adhesion Molecules; Collagen Type I; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glutamine; Lipocalin-2; Lipocalins; Male; Proto-Oncogene Proteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transforming Growth Factor beta1 | 2016 |
Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
Topics: Adaptation, Biological; Amino Acids; Animals; Aspartate-Ammonia Ligase; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Female; Glutamine; Heterografts; Humans; Mice; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Burden | 2016 |
Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models.
Topics: Animals; Autophagy; Cell Line, Tumor; Disease Models, Animal; Female; Glucose; Glutamates; Glutamine; Glycolysis; Heterografts; Humans; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Mice; Mitochondria; Ovarian Neoplasms; Oxidative Stress; Positron Emission Tomography Computed Tomography; rho GTP-Binding Proteins | 2016 |
Enzyme activities involved in the glutamate-glutamine cycle are altered to reduce glutamate after spinal cord injury in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme Activation; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors | 2016 |
Glutamine Prevents Late-Phase Anaphylaxis via MAPK Phosphatase 1-Dependent Cytosolic Phospholipase A2 Deactivation.
Topics: Anaphylaxis; Animals; Disease Models, Animal; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Glutamine; Leukotriene B4; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Phosphorylation; Platelet Activating Factor; RNA, Small Interfering | 2016 |
Metabolic fate of glucose in rats with traumatic brain injury and pyruvate or glucose treatments: A NMR spectroscopy study.
Topics: Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Male; Pyruvic Acid; Rats, Sprague-Dawley | 2017 |
Early Administration of Glutamine Protects Cardiomyocytes from Post-Cardiac Arrest Acidosis.
Topics: Acidosis; Animals; Cells, Cultured; Disease Models, Animal; Glutamine; Heart Arrest; Humans; Hydrogen-Ion Concentration; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Rats; Rats, Wistar | 2016 |
Effect of Previous High Glutamine Infusion on Inflammatory Mediators and Mortality in an Acute Pancreatitis Model.
Topics: Acute Disease; Animals; Cytokines; Disease Models, Animal; Glutamine; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Inflammation; Infusions, Intravenous; Interferon-gamma; Liver; Lung; Male; Pancreatitis; Rats; Rats, Inbred Lew; Taurocholic Acid; Time Factors | 2016 |
Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development.
Topics: Animals; Chlorides; Dentate Gyrus; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamine; Mice; Neural Inhibition; Neurons | 2017 |
MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.
Topics: Animals; Cell Line, Tumor; Cluster Analysis; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Glutamine; Glutathione; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Transgenic; MicroRNAs; Oxidative Stress; Proto-Oncogene Proteins c-myc; RNA Interference | 2017 |
Modeling human methamphetamine use patterns in mice: chronic and binge methamphetamine exposure, reward function and neurochemistry.
Topics: Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Glutamine; Methamphetamine; Mice; Reward; Self Stimulation; Serotonin | 2018 |
Parachlorophenylalanine-induced 5-HT depletion alters behavioral and brain neurotransmitters levels in 6-Hz psychomotor seizure model in mice.
Topics: Animals; Brain; Disease Models, Animal; Electroshock; gamma-Aminobutyric Acid; Glutamine; Male; Mice; Neurotransmitter Agents; Phenylalanine; Psychomotor Agitation; Seizures; Serotonin; Valproic Acid | 2017 |
L-Gln and L-Ser suppress the D-galactosamine-induced IL-18 expression and hepatitis.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Diet; Disease Models, Animal; Galactosamine; Glutamine; Interleukin-18; Male; Rats; Rats, Wistar; RNA, Messenger; Serine; Transaminases | 2008 |
The androgen receptor's CAG/glutamine tract in mouse models of neurological disease and cancer.
Topics: Alleles; Animals; Crosses, Genetic; Disease Models, Animal; Gene Targeting; Genetic Predisposition to Disease; Glutamine; Humans; Male; Mice; Mice, Knockout; Mice, Transgenic; Motor Neurons; Muscle, Skeletal; Muscular Atrophy, Spinal; Phenotype; Prostatic Neoplasms; Receptors, Androgen; Spinal Cord; Trinucleotide Repeats | 2008 |
Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats.
Topics: Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Glutamine; GTP-Binding Proteins; Guanosine Diphosphate; Hypertension; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neuronal Plasticity; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-B; Staining and Labeling; Sympathetic Nervous System; Synaptic Transmission; Thionucleotides | 2008 |
Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis.
Topics: Analysis of Variance; Animals; Blotting, Western; Colitis; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glutamine; Inflammation Mediators; Male; Manometry; NF-kappa B; Oxidative Stress; Probability; Random Allocation; Rats; Sensitivity and Specificity; Signal Transduction; Statistics, Nonparametric; Transcription, Genetic; Trinitrobenzenesulfonic Acid; Up-Regulation | 2008 |
[The different effects of glutamine on macrophage cytokines release in vivo and in vitro].
Topics: Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Glutamine; HSP72 Heat-Shock Proteins; Interleukin-10; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Random Allocation; Sepsis; Tumor Necrosis Factor-alpha | 2008 |
Glutamatergic inputs to the CVLM independent of the NTS promote tonic inhibition of sympathetic vasomotor tone in rats.
Topics: Animals; Baroreflex; Blood Pressure; Blood Vessels; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Glutamine; Hypotension; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Nitroprusside; Rats; Rats, Sprague-Dawley; Respiratory Center; Solitary Nucleus; Splanchnic Nerves; Sympathetic Nervous System; Time Factors; Vagotomy | 2008 |
miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis.
Topics: Animals; Ataxin-1; Ataxins; Cell Line, Transformed; Cerebellum; Disease Models, Animal; Gene Expression Regulation; Glutamine; Green Fluorescent Proteins; Humans; Mice; Mice, Transgenic; MicroRNAs; Nerve Tissue Proteins; Nuclear Proteins; Phenylalanine; Purkinje Cells; RNA, Small Interfering; Spinocerebellar Ataxias; Time Factors; Transfection; Trinucleotide Repeat Expansion | 2008 |
Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS.
Topics: Age Factors; Amidohydrolases; Animals; Animals, Newborn; Aspartic Acid; Axons; Behavior, Animal; Canavan Disease; Central Nervous System; Chromosome Mapping; Codon, Nonsense; Disease Models, Animal; Disease Progression; Glutamine; Lipid Metabolism; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Sheath; N-Acylsphingosine Galactosyltransferase; Oligodendroglia | 2008 |
Neurochemical changes in a mouse model of Rett syndrome: changes over time and in response to perinatal choline nutritional supplementation.
Topics: Age Factors; Animals; Animals, Newborn; Aspartic Acid; Brain; Choline; Creatine; Dietary Supplements; Disease Models, Animal; DNA-Binding Proteins; Glutamic Acid; Glutamine; Histone Deacetylases; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Nootropic Agents; Rett Syndrome; Spectrum Analysis | 2009 |
Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes.
Topics: Animals; Burns; CD11b Antigen; Cell Adhesion; Disease Models, Animal; Endothelial Cells; Glutamine; Humans; Lactose; Leukocytes; Male; Oligosaccharides; Propanolamines; Rats; Rats, Sprague-Dawley; Shock; Time Factors; Transfection | 2009 |
[Effects of glutamine on changes of nuclear factor-kappa B in acute lipopolysaccharide lung injury: experiment with rats].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glutamine; Lipopolysaccharides; Lung; Male; Malondialdehyde; NF-kappa B; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2008 |
Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia.
Topics: Ammonia; Animals; Astrocytes; Brain; Carbon Radioisotopes; Cells, Cultured; Cholestasis; Citric Acid Cycle; Disease Models, Animal; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Isoleucine; Muscle, Skeletal; Neurons; Rats; Rats, Wistar | 2009 |
Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Bacterial Translocation; Body Weight; Cells, Cultured; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Eating; Feces; Flagellin; Glutamine; Immunoglobulin A, Secretory; Intestines; Lymph Nodes; Male; Membrane Proteins; Metronidazole; Neomycin; Occludin; Phosphoproteins; Plasma Cells; Polymyxin B; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome; Tight Junctions; Time Factors; Zonula Occludens-1 Protein | 2009 |
Glutamine in acute lung injury: the experimental model matters.
Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Glutamine; Heat-Shock Proteins; Lipopolysaccharides; Mice; Thiobarbituric Acid Reactive Substances | 2009 |
Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminoisobutyric Acids; Animals; Bicuculline; Disease Models, Animal; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamine; In Vitro Techniques; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2009 |
Different effect of glutamine on macrophage tumor necrosis factor-alpha release and heat shock protein 72 expression in vitro and in vivo.
Topics: Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Heat-Shock Response; HSP72 Heat-Shock Proteins; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Sepsis; Tumor Necrosis Factor-alpha | 2009 |
Glutamine attenuates lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Buthionine Sulfoximine; CD11b Antigen; CD18 Antigens; Disease Models, Animal; Glutamine; Glutathione; Inflammation; Interleukin-8; Lipopolysaccharides; Lung; Male; Neutrophils; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Glutamine decreases inflammation in infant rat endotoxemia.
Topics: Animals; Animals, Newborn; Cytokines; Disease Models, Animal; Endotoxemia; Escherichia coli; Escherichia coli Infections; Glutamine; Hepatocytes; Inflammation; Injections, Intraperitoneal; Interleukin-10; Lipid Peroxidation; Mitochondria, Liver; Nitric Oxide; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2009 |
Protective effects of glutamine dipeptide and alpha-tocopherol against ischemia-reperfusion injury in the isolated rat liver.
Topics: alpha-Tocopherol; Animals; Dipeptides; Disease Models, Animal; Drug Combinations; Glutamine; Glutathione; Liver; Male; Nitric Oxide; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2009 |
Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases.
Topics: Animals; Asparagine; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Intranuclear Inclusion Bodies; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Structure, Tertiary; Protein Transport; RNA-Binding Proteins; Solubility | 2009 |
The preliminary experimental and clinical study of the relationship between the pigment gallstone and intestinal mucosal barrier.
Topics: Amine Oxidase (Copper-Containing); Animals; Bacterial Translocation; Bile; Bile Pigments; Case-Control Studies; Cholesterol; Disease Models, Animal; Endotoxins; Female; Gallstones; Glucuronidase; Glutamine; Guinea Pigs; Humans; Intestinal Mucosa; Lactulose; Lymph Nodes; Male; Mannitol; Permeability; Pilot Projects; Radiopharmaceuticals; Technetium Tc 99m Pentetate | 2009 |
Roux-en-Y gastric bypass alters small intestine glutamine transport in the obese Zucker rat.
Topics: Amino Acid Transport Systems, Neutral; Animals; Biological Transport; Disease Models, Animal; Gastric Bypass; Gluconeogenesis; Glucose-6-Phosphatase; Glutaminase; Glutamine; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Up-Regulation | 2009 |
Glutamine attenuates hyperoxia-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Edema; Glutamine; Heat-Shock Proteins; Hyperoxia; Lung; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Organ Size; Peroxidase; Random Allocation; Survival Analysis | 2010 |
Attenuation of lipopolysaccharide-mediated left ventricular dysfunction by glutamine preconditioning.
Topics: Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Glutamine; Heart Rate; HSP72 Heat-Shock Proteins; Ischemic Preconditioning, Myocardial; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Quercetin; Ventricular Dysfunction, Left | 2010 |
[Changes in expressions of the myocardial Toll-like receptor 4, tumor necrosis factor-alpha and interleukin-6 mRNA in rat with sepsis].
Topics: Animals; Apoptosis; Disease Models, Animal; Glutamine; Interleukin-6; Male; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2009 |
Glutamine supplementation does not improve protein synthesis rate by the jejunal mucosa of the malnourished rat.
Topics: Amino Acids; Animals; Body Weight; Carbon Isotopes; Dietary Supplements; Disease Models, Animal; Glutamine; Intestinal Mucosa; Jejunum; Leucine; Male; Nitrogen; Protein Biosynthesis; Protein-Energy Malnutrition; Random Allocation; Rats; Rats, Wistar; Reference Values | 2009 |
Effects of glutamine added to enteral nutrition on Peyer's patch apoptosis in severely burned mice.
Topics: Animals; Apoptosis; Burns; Caspase 3; Disease Models, Animal; Drug Evaluation, Preclinical; Enteral Nutrition; Fas Ligand Protein; Gene Expression Regulation; Glutamine; Lymphocyte Subsets; Male; Mice; Mice, Inbred BALB C; Peyer's Patches; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2010 |
Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Biomarkers; Brain; Creatine; Disease Models, Animal; Glutamic Acid; Glutamine; In Vitro Techniques; Inositol; Linear Models; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Protons; Spectrum Analysis; Superoxide Dismutase | 2009 |
Methionine sulfoximine, an inhibitor of glutamine synthetase, lowers brain glutamine and glutamate in a mouse model of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Corpus Striatum; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Humans; Kaplan-Meier Estimate; Magnetic Resonance Spectroscopy; Methionine Sulfoximine; Mice; Mice, Transgenic; Motor Cortex; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Treatment Outcome | 2010 |
Reduction of liver ischemia-reperfusion injury via glutamine pretreatment.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dipeptides; Disease Models, Animal; Glutamine; In Situ Nick-End Labeling; Ischemic Preconditioning; Laser-Doppler Flowmetry; Liver Circulation; Liver Diseases; Male; Microcirculation; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury | 2011 |
Protective effect of glutamine-enriched early enteral nutrition on intestinal mucosal barrier injury after liver transplantation in rats.
Topics: Animals; Bacterial Translocation; Biomarkers; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Enteral Nutrition; Glutamine; Immunohistochemistry; Intestinal Diseases; Intestinal Mucosa; Lactic Acid; Liver Transplantation; Male; Malondialdehyde; Polymerase Chain Reaction; Postoperative Complications; Probability; Random Allocation; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Proteasomal degradation of glutamine synthetase regulates schwann cell differentiation.
Topics: Animals; Animals, Newborn; Carrier Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamine; Humans; Mice; Myelin Sheath; Nerve Regeneration; Oxidative Stress; Peripheral Nervous System Diseases; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schwann Cells; Ubiquitin-Protein Ligases | 2010 |
Different alterations in rat intestinal glutamine transport during the progression of CLP- and LPS-induced sepsis.
Topics: Animals; Biological Transport; Carrier Proteins; Cecum; Disease Models, Animal; Glutamine; Interleukin-10; Intestinal Mucosa; Intestines; Ligation; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha | 2011 |
Desipramine attenuates forced swim test-induced behavioral and neurochemical alterations in mice: an in vivo(1)H-MRS study at 9.4T.
Topics: Animals; Behavior, Animal; Brain Chemistry; Choline; Creatine; Desipramine; Disease Models, Animal; Enzyme Inhibitors; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphocreatine; Prefrontal Cortex; Protons; Stress, Psychological; Swimming | 2010 |
The effects of oral glutamine on cyclophosphamide-induced nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Disease Models, Animal; Glutamine; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar | 2011 |
Oral glutamine attenuates cyclophosphamide-induced oxidative stress in the bladder but does not prevent hemorrhagic cystitis in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cystitis; Disease Models, Animal; Glutamine; Hemorrhage; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar | 2011 |
Influence of glutamine on morphological and functional changes of liver in the presence of extrahepatic biliary obstruction in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Ducts, Extrahepatic; Cholestasis, Extrahepatic; Disease Models, Animal; Enteral Nutrition; Glutamine; Hepatic Duct, Common; Liver; Male; Postoperative Complications; Rats; Rats, Wistar | 2010 |
Lymph duct ligation during ischemia/reperfusion prevents pulmonary dysfunction in a rat model with ω-3 polyunsaturated fatty acid and glutamine.
Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Endotoxins; Fatty Acids, Omega-3; Glutamine; Inflammation; Intestinal Diseases; Intestines; Ligation; Lipopolysaccharides; Lung Injury; Lymph Nodes; Lymphatic System; Male; Mesentery; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2011 |
The effects of oral liquid and intravenous glutamine on bowel adaptation in a rabbit short bowel syndrome model.
Topics: Adaptation, Physiological; Administration, Oral; Animals; Disease Models, Animal; Dosage Forms; Glutamine; Injections, Intravenous; Male; Rabbits; Short Bowel Syndrome | 2010 |
Protective mechanism of glutamine on the expression of proliferating cell nuclear antigen after cisplatin-induced intestinal mucosal injury.
Topics: Animals; Cisplatin; Disease Models, Animal; DNA; Gene Expression; Glutamine; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Chronic electrographic seizure reduces glutamine and elevates glutamate in the extracellular fluid of rat brain.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Extracellular Fluid; Glutamic Acid; Glutamine; Hippocampus; Intracellular Fluid; Kainic Acid; Male; Microdialysis; Neurotoxins; Rats; Rats, Wistar; Synaptic Vesicles | 2011 |
New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA.
Topics: Acyl Coenzyme A; Amino-Acid N-Acetyltransferase; Ammonia; Animals; Anticonvulsants; Citrulline; Disease Models, Animal; Glutamates; Glutamine; Humans; Hyperammonemia; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Models, Biological; Rats; Rats, Wistar; Urea; Valproic Acid | 2011 |
Lateral superior olive function in congenital deafness.
Topics: Animals; Auditory Pathways; Auditory Perception; Carrier Proteins; Cochlear Nerve; Deafness; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Excitatory Postsynaptic Potentials; Glutamine; Glycine; Immunohistochemistry; Membrane Proteins; Mice; Mice, Mutant Strains; Models, Neurological; Mutation; Neural Inhibition; Olivary Nucleus; Patch-Clamp Techniques; Time Factors | 2011 |
GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium.
Topics: Adult; Animals; Biomarkers; Body Weight; Case-Control Studies; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Male; Metabolomics; Mice; Mice, Inbred C57BL; Middle Aged | 2011 |
Early predictive biomarkers for lesion after transient cerebral ischemia.
Topics: Animals; Aspartic Acid; Biomarkers; Disease Models, Animal; Glutamine; Ischemic Attack, Transient; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Predictive Value of Tests; Taurine; Time Factors | 2011 |
The effect of glutamine on oxidative damage in an experimental abdominal compartment syndrome model in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Compartment Syndromes; Disease Models, Animal; Glutamine; Glutathione; Intestines; Liver; Lung; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Pressure; Rats; Rats, Wistar | 2011 |
Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models.
Topics: Animals; Area Under Curve; Caspase 3; Cell Survival; Colitis; Colon; Cytokines; Dextran Sulfate; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Glutamine; Heat-Shock Proteins; Hemorrhage; HSP70 Heat-Shock Proteins; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley | 2011 |
Glutamine restores myocardial cytochrome C oxidase activity and improves cardiac function during experimental sepsis.
Topics: Animals; Blood Pressure; Cardiovascular Agents; Disease Models, Animal; Electron Transport Complex IV; Glutamine; Heart; Heart Ventricles; Male; Muscle Contraction; Myocardium; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Sepsis | 2011 |
Glutamine contributes to ameliorate inflammation after renal ischemia/reperfusion injury in rats.
Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Glutamine; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Nephritis; Rats; Rats, Wistar; Reperfusion Injury | 2011 |
A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses.
Topics: Animals; Cerebellum; Cerebral Cortex; Disease Models, Animal; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Mice; Neuronal Ceroid-Lipofuscinoses; Neurons; Pigments, Biological | 2011 |
Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation under high-altitude hypoxic environment.
Topics: Altitude; Amine Oxidase (Copper-Containing); Animals; Apoptosis; Bacterial Translocation; Disease Models, Animal; Endotoxins; Glutamine; Hypoxia; In Situ Nick-End Labeling; Intestinal Diseases; Intestinal Mucosa; Intestines; Lymph Nodes; Male; Malondialdehyde; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spleen; Starvation; Superoxide Dismutase; Time Factors | 2011 |
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry | 2011 |
p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.
Topics: Ammonia; Animals; Blotting, Western; Cerebellum; Cerebral Cortex; Cognition; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Imidazoles; Immunohistochemistry; Learning; Male; MAP Kinase Signaling System; Microglia; Motor Activity; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Portacaval Shunt, Surgical; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Rats; Rats, Wistar | 2011 |
Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration.
Topics: Adult; Animals; Animals, Genetically Modified; Disease Models, Animal; Disease Progression; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Opsins; Rabbits; Retina; Retinal Degeneration; Retinitis Pigmentosa; Taurine | 2011 |
Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G).
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Color Therapy; Disease Models, Animal; Endopeptidase K; Glutamine; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Transgenic; Mutation; Oxidation-Reduction; Protein Binding; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc | 2011 |
L-glutamine supplementation prevents myenteric neuron loss and has gliatrophic effects in the ileum of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Supplements; Disease Models, Animal; Glutamine; Ileum; Immunohistochemistry; Male; Microscopy, Confocal; Myenteric Plexus; Neuroglia; Neuroprotective Agents; Rats; Rats, Wistar; Treatment Outcome | 2011 |
Simultaneously changes in striatum dopaminergic and glutamatergic parameters following hypoxic-ischemic neuronal injury in newborn piglets.
Topics: Animals; Animals, Newborn; Basal Ganglia; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Glutamine; Hypoxia-Ischemia, Brain; Immunohistochemistry; Magnetic Resonance Spectroscopy; Male; Neurons; Receptors, Dopamine D2; Swine | 2012 |
Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression.
Topics: Animals; Choline; Depression; Disease Models, Animal; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Helplessness, Learned; Hippocampus; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Taurine | 2012 |
NMR and pattern recognition can distinguish neuroinflammation and peripheral inflammation.
Topics: Animals; Citrates; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamine; Humans; Inflammation; Lactates; Magnetic Resonance Spectroscopy; Male; Models, Statistical; Multiple Sclerosis; Mycobacterium tuberculosis; Pattern Recognition, Automated; Pentanoic Acids; Rats; Rats, Inbred Lew; Reproducibility of Results | 2011 |
Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis.
Topics: Amino Acids; Ammonia; Animals; Brain; Disease Models, Animal; Evoked Potentials, Motor; Glutamine; Hepatic Encephalopathy; Male; Ornithine; Phenylacetates; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley | 2012 |
Endotoxemia affects citrulline, arginine and glutamine bioavailability.
Topics: Animals; Area Under Curve; Arginine; Biological Availability; Citrulline; Disease Models, Animal; Endotoxemia; Glutamine; Lipopolysaccharides; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia | 2012 |
Effect of glutamine on the mRNA level of key enzymes of malate-aspartate shuttle in the rat intestine subjected to ischemia reperfusion.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Dipeptides; Disease Models, Animal; Glutamine; Intestine, Small; Malate Dehydrogenase; Malates; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger; Time Factors | 2011 |
Effects of dietary glutamine on inflammatory mediator gene expressions in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Experimental; Dietary Supplements; Disease Models, Animal; Down-Regulation; Fructosamine; Gene Expression; Glutamine; Inflammation; Inflammation Mediators; Interleukin-17; Interleukin-23; Interleukin-6; Leukocytes, Mononuclear; Male; Niacinamide; Rats; Rats, Wistar; RNA, Messenger; Th17 Cells; Transforming Growth Factor beta1 | 2012 |
Arginyl-glutamine dipeptide or docosahexaenoic acid attenuates hyperoxia-induced small intestinal injury in neonatal mice.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; Dietary Supplements; Dipeptides; Disease Models, Animal; Docosahexaenoic Acids; Female; Glutamine; Hyperoxia; Intestinal Mucosa; Intestine, Small; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Peroxidase | 2012 |
Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol.
Topics: Animals; Carbon Tetrachloride; Cell Differentiation; Cell Lineage; Cell Transplantation; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Glutamine; Hepatocyte Growth Factor; Hepatocytes; Humans; In Vitro Techniques; Liver Failure; Mice; Mice, SCID; Oncostatin M; Pluripotent Stem Cells; Treatment Outcome | 2012 |
Glutamine prevents intestinal mucosal injury induced by cyclophosphamide in rats.
Topics: Administration, Oral; Animals; Apoptosis; Cell Proliferation; Cyclophosphamide; Disease Models, Animal; Enterocytes; Glutamine; Ileal Diseases; Ileum; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Rats; Rats, Wistar; Treatment Outcome | 2012 |
Gu-4 suppresses affinity and avidity modulation of CD11b and improves the outcome of mice with endotoxemia and sepsis.
Topics: Animals; CD11b Antigen; Cell Adhesion; Disease Models, Animal; Endotoxemia; Glutamine; Lactose; Leukocytes; Lymphocyte Activation; Mice; Microcirculation; Sepsis; Survival Rate | 2012 |
Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Cell Survival; Disease Models, Animal; DNA Damage; Gene Expression; Glutamate-Ammonia Ligase; Glutamine; Hippocampus; Humans; Hydrogen Peroxide; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Stress, Physiological | 2012 |
Effects of enteral and parenteral glutamine on intestinal mucosa and on levels of blood glutamine, tumor necrosis factor-alpha, and interleukin-10 in an experimental sepsis model.
Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glutamine; Injections, Intraperitoneal; Interleukin-1; Intestinal Mucosa; Rats; Rats, Wistar; Sepsis; Tumor Necrosis Factor-alpha | 2012 |
Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Respiration; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Doxycycline; Electron Transport; Gene Expression Regulation, Neoplastic; Genes, myc; Glutamine; Homeostasis; Humans; Liver Neoplasms; Mechanistic Target of Rapamycin Complex 1; Mice; Mitochondria; Multiprotein Complexes; Oncogene Protein p55(v-myc); Protein Biosynthesis; Protein Kinases; Proteins; Repressor Proteins; RNA Interference; Signal Transduction; TOR Serine-Threonine Kinases | 2012 |
Glutamine preconditioning protects against local and systemic injury induced by orthopaedic surgery.
Topics: Animals; Bronchoalveolar Lavage; Disease Models, Animal; Femoral Fractures; Glutamine; Ischemic Preconditioning; Male; Muscle, Skeletal; Orthopedic Procedures; Protective Agents; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2012 |
Neuroprotective effects of angiotensin II type 1 receptor (AT1-R) blocker via modulating AT1-R signaling and decreased extracellular glutamate levels.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Survival; Disease Models, Animal; Electroretinography; Extracellular Fluid; Gene Expression Regulation; Glutamine; Immunohistochemistry; Male; NADPH Oxidases; Phosphoproteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reperfusion Injury; Retina; Retinal Diseases; Retinal Ganglion Cells; RNA, Messenger; Signal Transduction; Tetrazoles; Vitreous Body | 2012 |
Therapeutic effects of lactosyl derivative Gu-4 in a collagen-induced arthritis rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cattle; Cell Proliferation; Cells, Cultured; Collagen Type II; Disease Models, Animal; Drug Administration Schedule; Edema; Etanercept; Female; Glutamine; Humans; Immunoglobulin G; Joints; Lactose; Lymphocytes; Organ Size; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Rheumatoid Factor | 2012 |
[Impact of glutamine and ω-3 polyunsaturated fatty acids on intestinal permeability and lung cell apoptosis during intestinal ischemia-reperfusion injury in a rat model].
Topics: Animals; Apoptosis; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Intestines; Ligation; Lung; Lymphatic Vessels; Male; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2012 |
Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Dependovirus; Disease Models, Animal; Female; Genetic Vectors; Glutamine; Huntingtin Protein; Huntington Disease; Hypothalamus; Inclusion Bodies; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Mutation; Nerve Tissue Proteins; Neuropeptides; Nuclear Proteins; Orexins; Prosencephalon; Rats; Rats, Sprague-Dawley | 2012 |
Protective effects of glutamine in a rat model of endotoxemia.
Topics: Animals; Apoptosis; Brain; Disease Models, Animal; Endotoxemia; Female; Glutamine; HSP70 Heat-Shock Proteins; Lipopolysaccharides; Male; Neurons; Neuroprotective Agents; NF-kappa B; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Up-Regulation | 2012 |
Modulation of the nuclear factor-kappa B (NF-κB) signalling pathway by glutamine in peritoneal macrophages of a murine model of protein malnutrition.
Topics: Animals; Animals, Outbred Strains; Cells, Cultured; Corticosterone; Dietary Supplements; Disease Models, Animal; Down-Regulation; Glutamine; Immunomodulation; Interleukin-1alpha; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Protein-Energy Malnutrition; Signal Transduction | 2013 |
Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis.
Topics: Administration, Rectal; Animals; Apoptosis; Butyrates; Colitis; Colon; Colostomy; Cytokines; Disease Models, Animal; Endoscopy, Gastrointestinal; Enema; Female; Fibrosis; Glutamine; Inflammation; Intestinal Mucosa; Male; Rats; Rats, Wistar | 2012 |
Effects of glutamine treatment on myocardial damage and cardiac function in rats after severe burn injury.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Aspartate Aminotransferases; Biomarkers; Burns; Creatine Kinase, MB Form; Disease Models, Animal; Edema, Cardiac; Glutamine; Glutathione; Heart; Heart Diseases; Heart Function Tests; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Protective Agents; Rats; Rats, Wistar; Water | 2012 |
Disrupted-in-schizophrenia-1 Gln31Leu polymorphism results in social anhedonia associated with monoaminergic imbalance and reduction of CREB and β-arrestin-1,2 in the nucleus accumbens in a mouse model of depression.
Topics: Anhedonia; Animals; Antidepressive Agents; Arrestins; beta-Arrestin 1; beta-Arrestins; Biogenic Monoamines; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Glutamine; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nucleus Accumbens; Polymorphism, Genetic; Signal Transduction | 2013 |
Glutamine suppresses DNFB-induced contact dermatitis by deactivating p38 mitogen-activated protein kinase via induction of MAPK phosphatase-1.
Topics: Animals; Butadienes; Cell Line; Cells, Cultured; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Female; Glutamine; Humans; Keratinocytes; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Small Interfering | 2013 |
Effects of glutamine supplementation on muscle function and stress responses in a mouse model of spinal cord injury.
Topics: Animals; Disease Models, Animal; Glutamine; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Muscle, Skeletal; Myofibrils; Neoplasm Proteins; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2013 |
Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice.
Topics: Animals; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Dietary Fiber; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Interleukin-1beta; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Oligosaccharides; RNA, Messenger | 2013 |
Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model.
Topics: Animals; Disease Models, Animal; Gastrointestinal Tract; Glutamine; Graft vs Host Disease; Jejunum; Lymphocyte Transfusion; Mice; Occludin; Permeability; Tumor Necrosis Factor-alpha | 2013 |
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation.
Topics: Aging; Animals; Biological Transport; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microdialysis; Mutation; Nerve Tissue Proteins; Nuclear Proteins | 2002 |
The conserved glutamine-rich region of chick csal1 and csal3 mediates protein interactions with other spalt family members. Implications for Townes-Brocks syndrome.
Topics: Amino Acid Sequence; Animals; Cell Line; Chick Embryo; Conserved Sequence; Disease Models, Animal; Extremities; Glutamine; Homeodomain Proteins; Humans; Molecular Sequence Data; Morphogenesis; Peptide Fragments; Protein Isoforms; Recombinant Proteins; Syndrome; Transcription Factors; Transfection; Xenopus Proteins; Zinc Fingers | 2003 |
Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus.
Topics: Acetates; Animals; Astrocytes; Biomarkers; Brain Stem; Carbon Isotopes; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Hydrocephalus; Kaolin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Taurine; Telencephalon | 2003 |
Role of manganese accumulation in increased brain glutamine of the cirrhotic rat.
Topics: Animals; Brain; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Cirrhosis, Experimental; Male; Manganese; Organ Specificity; Rats; Rats, Wistar; Time Factors | 2003 |
Nutritional benefits of enteral alanyl-glutamine supplementation on rat small intestinal damage induced by cyclophosphamide.
Topics: Alanine; Amino Acid Transport Systems; Animals; Antineoplastic Agents, Alkylating; Biomarkers; Body Weight; Cadherins; Carrier Proteins; Cyclophosphamide; Dietary Supplements; Dipeptides; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 2003 |
The effect of immunonutrition on bacterial translocation, and intestinal villus atrophy in experimental obstructive jaundice.
Topics: Animals; Arginine; Atrophy; Bacterial Translocation; Cholestasis, Extrahepatic; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Intestinal Mucosa; Liver; Lymph Nodes; Male; Mesentery; Nutritional Physiological Phenomena; Random Allocation; Rats; Rats, Wistar; RNA; Spleen | 2003 |
Cellular energetics in hemorrhagic shock: restoring adenosine triphosphate to the cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Antioxidants; Apoptosis; Carotenoids; Disease Models, Animal; Energy Metabolism; Fluid Therapy; Glutamine; Intestine, Small; Liver; Male; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Vitamin A | 2003 |
Obstructive jaundice alters proliferating cell nuclear antigen expression in rat small intestine.
Topics: Animals; Common Bile Duct; Disease Models, Animal; Glutamine; Intestinal Mucosa; Intestine, Small; Jaundice, Obstructive; Ligation; Male; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
The role of dietary supplementation with L-glutamine in inflammatory mediator release and intestinal injury in hypoxia/reoxygenation-induced experimental necrotizing enterocolitis.
Topics: Administration, Oral; Animals; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocolitis, Necrotizing; Glutamine; Hypoxia; Intestinal Mucosa; Intestines; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Random Allocation; Tumor Necrosis Factor-alpha | 2003 |
Effects of dietary glutamine on antioxidant enzyme activity and immune response in burned mice.
Topics: Animals; Antibody Formation; Antioxidants; Bacterial Vaccines; Burns; Diet; Disease Models, Animal; Glutamine; Male; Mice; Mice, Inbred BALB C; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Survival Analysis | 2003 |
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured | 2003 |
Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
Topics: Animals; Ataxin-7; beta-Galactosidase; Blotting, Western; Cell Nucleus; Cells, Cultured; Disease Models, Animal; DNA Primers; Gene Expression Regulation; Genetic Vectors; Glutamine; Homeodomain Proteins; Immunohistochemistry; Luciferases; Mice; Mutagenesis; Nerve Tissue Proteins; Photoreceptor Cells, Vertebrate; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retinal Degeneration; Spinocerebellar Ataxias; Trans-Activators; Transcription, Genetic; Two-Hybrid System Techniques | 2004 |
Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3.
Topics: Animals; Ataxin-3; Brain; Cerebellum; Choline; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamine; Glycogen; Humans; Lactic Acid; Machado-Joseph Disease; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Phosphorylcholine; Repressor Proteins; Telencephalon; Transcription Factors; Trinucleotide Repeat Expansion | 2004 |
Impaired energy metabolism during neonatal sepsis: the effects of glutamine.
Topics: Animals; Animals, Suckling; Basal Metabolism; Disease Models, Animal; Endotoxemia; Energy Metabolism; Glutamine; Humans; Infant, Newborn; Rats; Sepsis; Thermogenesis | 2003 |
Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding.
Topics: Animals; Brain; Disease Models, Animal; Dopamine; Female; Fetus; Glutamine; Male; Neural Inhibition; Pregnancy; Prenatal Nutritional Physiological Phenomena; Protein Deficiency; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Sex Factors; Time Factors | 2004 |
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia.
Topics: Animals; Brain Edema; Disease Models, Animal; Glutamine; Hepatic Encephalopathy; Hypothermia, Induced; Inositol; Intracranial Hypertension; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Taurine | 2004 |
Glutamatergic regulation of long-term grafts of fetal lateral ganglionic eminence in a rat model of Huntington's disease.
Topics: Animals; Brain Injuries; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Fetal Tissue Transplantation; Fluorescent Antibody Technique; Glutamine; Haloperidol; Huntington Disease; Immunohistochemistry; Male; Neurons, Afferent; Proto-Oncogene Proteins c-fos; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2004 |
Effect of glutamine and bile acid on hepatocyte apoptosis after bile duct ligation in the rat.
Topics: Administration, Oral; Animals; Apoptosis; Cholestasis, Extrahepatic; Common Bile Duct; Deoxycholic Acid; Disease Models, Animal; Glutamine; Hepatocytes; Ligation; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2004 |
Evolution of expression of cardiac phenotypes over a 4-year period in the beta-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy.
Topics: Adenosine Triphosphatases; Aging; Animals; Animals, Genetically Modified; Calcium; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Echocardiography; Glutamine; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myofibrils; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Phenotype; Rabbits; Signal Transduction; Time Factors; Transgenes | 2004 |
Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose.
Topics: Animals; Blood Glucose; Brain; Carbon Isotopes; Disease Models, Animal; Energy Metabolism; gamma-Aminobutyric Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Manganese; Manganese Poisoning; Rats; Rats, Sprague-Dawley | 2004 |
Effects of protein deprivation on growth and small intestine morphology are not improved by glutamine or glutamate in gastrostomy-fed rat pups.
Topics: Alkaline Phosphatase; alpha-Glucosidases; Animals; Animals, Newborn; Claudin-1; Dietary Proteins; Disease Models, Animal; Gastrostomy; Glutamic Acid; Glutamine; Immunoblotting; Intestinal Mucosa; Intestine, Small; Membrane Proteins; Occludin; Random Allocation; Rats; Rats, Sprague-Dawley; Tight Junctions; Weight Gain | 2004 |
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.
Topics: Adenoviridae; Animals; Ataxin-1; Ataxins; Blotting, Northern; Brain; Cells, Cultured; Disease Models, Animal; Gene Expression; Glutamine; Immunohistochemistry; Mice; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Plasmids; Psychomotor Performance; Purkinje Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spinocerebellar Ataxias; Transduction, Genetic | 2004 |
Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency.
Topics: Aldehyde Oxidoreductases; Amino Acids; Animals; Brain; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Succinate-Semialdehyde Dehydrogenase | 2004 |
RNAi quashes polyQ.
Topics: Adenoviridae; Animals; Ataxin-1; Ataxins; Brain; Disease Models, Animal; Genetic Vectors; Glutamine; Humans; Mice; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Purkinje Cells; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spinocerebellar Ataxias | 2004 |
In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death.
Topics: Animals; Apoptosis; Brain; Brain Injuries; Cell Death; Cell Survival; Denervation; Disease Models, Animal; Energy Metabolism; Fornix, Brain; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hippocampus; L-Lactate Dehydrogenase; Lactic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley | 2004 |
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
Topics: Age Factors; Aged; Aged, 80 and over; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Blood Vessels; Blotting, Western; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; Encephalitis; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Glutamine; Humans; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron; Middle Aged; Mutation; Peptide Fragments; Pia Mater; Postmortem Changes; Thy-1 Antigens | 2004 |
Arginine and glutamine availability and macrophage functions in the obese insulin-resistant Zucker rat.
Topics: Animals; Arginine; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Genetic Predisposition to Disease; Glutamine; Immune System; Immunity, Innate; Infections; Insulin Resistance; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; Obesity; Rats; Rats, Zucker; Signal Transduction; Tumor Necrosis Factor-alpha | 2005 |
Absorption of enterally administered N-acetyl-l-glutamine versus glutamine in pigs.
Topics: Animals; Biological Availability; Digestion; Disease Models, Animal; Enteral Nutrition; Glucose; Glutamine; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Swine | 2004 |
Prophylactic administration of topical glutamine enhances the capability of the rat colon to resist inflammatory damage.
Topics: Adenosine Triphosphate; Administration, Topical; Animals; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Female; Glutamine; Glutathione; Guanosine Triphosphate; Intestinal Mucosa; Malondialdehyde; Mitotic Index; Rats; Rats, Inbred Strains | 2004 |
Cerebral glutamate metabolism in Parkinson's disease: an in vivo dynamic (13)C NMS study in the rat.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Carbon Isotopes; Disease Models, Animal; Dopamine; Glutamic Acid; Glutaminase; Glutamine; Infusions, Intravenous; Levodopa; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Sodium Acetate | 2005 |
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glycine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Rats; Rats, Wistar; Up-Regulation | 2005 |
Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Electrophoretic Mobility Shift Assay; Enteral Nutrition; Glutamine; Immunity, Mucosal; Immunologic Factors; Inflammation; Jejunum; Male; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Patient Selection; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Risk Factors; Time Factors; Transcription Factor AP-1 | 2005 |
[Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons].
Topics: Animals; Disease Models, Animal; Glutamine; Huntington Disease; Mammals; Mutation; Nematoda; Peptides; Resveratrol; Sirtuins; Stilbenes | 2005 |
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes; Choline; Disease Models, Animal; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Lupus Erythematosus, Systemic; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Protons; Up-Regulation | 2005 |
Lack of cardioprotection from metabolic support with glutamine or glutamate in a porcine coronary occlusion model.
Topics: Analysis of Variance; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Female; Glutamic Acid; Glutamine; Hemodynamics; Infusions, Intravenous; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Probability; Random Allocation; Reference Values; Risk Factors; Sensitivity and Specificity; Swine; Tomography, Emission-Computed, Single-Photon; Vascular Patency | 2005 |
Effect of oral glutamine administration on bacterial tanslocation, endotoxemia, liver and ileal morphology, and apoptosis in rats with obstructive jaundice.
Topics: Administration, Oral; Animals; Apoptosis; Bacterial Translocation; Disease Models, Animal; Endotoxemia; Gastrointestinal Agents; Glutamine; Ileum; Jaundice, Obstructive; Liver; Male; Rats; Rats, Wistar | 2005 |
[Effect of ecoimmunonutrition on gut barrier function in rats with systemic inflammatory response syndrome].
Topics: Animals; Disease Models, Animal; Enteral Nutrition; Glutamine; Intestinal Mucosa; Lactulose; Male; Rats; Rats, Sprague-Dawley; Systemic Inflammatory Response Syndrome | 2005 |
Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glutamic Acid; Glutamine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Confocal; Neuroprotective Agents; Organ Culture Techniques; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury.
Topics: Animals; Brain Injuries; Citric Acid Cycle; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Pentose Phosphate Pathway; Rats; Up-Regulation | 2005 |
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.
Topics: Aging; Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Knockout; Models, Biological; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neurotransmitter Agents; Phenotype; Spectrophotometry; Time Factors | 2005 |
Bcl-2 and Mn-SOD antisense oligodeoxynucleotides and a glutamine-enriched diet facilitate elimination of highly resistant B16 melanoma cells by tumor necrosis factor-alpha and chemotherapy.
Topics: Animal Feed; Animals; Antineoplastic Agents; Combined Modality Therapy; Disease Models, Animal; Drug Resistance, Neoplasm; Genetic Therapy; Glutamine; Glutathione; Male; Melanoma; Mice; Mice, Inbred C57BL; Mitochondria; Neoplasm Transplantation; Oligonucleotides, Antisense; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Soft Tissue Neoplasms; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2006 |
Intrinsic gluconeogenesis is enhanced in renal proximal tubules of Zucker diabetic fatty rats.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructose-Bisphosphatase; Gluconeogenesis; Glucose-6-Phosphatase; Glutamine; Glycerol; Kidney Tubules, Proximal; Lactic Acid; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Tissue Culture Techniques | 2006 |
Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models.
Topics: Animals; Calcium Channels, L-Type; Corpus Striatum; Dendritic Spines; Disease Models, Animal; Glutamine; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Neural Pathways; Organ Culture Techniques; Parkinson Disease; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; Synapses | 2006 |
Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Glutamine; HSP70 Heat-Shock Proteins; Injections, Intraperitoneal; Ischemia; Liver; Male; Necrosis; Neutrophils; Premedication; Protective Agents; Rats; Rats, Zucker; Reperfusion Injury; Survival Rate; Time Factors; Up-Regulation | 2006 |
Progressive disruption of cellular protein folding in models of polyglutamine diseases.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dynamin I; Glutamine; Humans; Mutation; Neurodegenerative Diseases; Peptides; Protein Folding; Temperature; Tropomyosin | 2006 |
Prevention of bacterial translocation using glutamine: a new strategy of investigation.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Glutamine; Intestinal Obstruction; Male; Random Allocation; Rats; Rats, Wistar | 2006 |
BIOMEDICINE: One Misfolded Protein Allows Others to Sneak By.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Glutamine; Humans; Huntington Disease; Mutation; Neurodegenerative Diseases; Peptides; Protein Conformation; Protein Folding; Temperature | 2006 |
Essential role of pepsin in pathogenesis of acid reflux esophagitis in rats.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Glutamine; Male; Pepsin A; Pepstatins; Protease Inhibitors; Rats; Rats, Sprague-Dawley | 2006 |
Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia.
Topics: Administration, Oral; Animals; Disease Models, Animal; DNA-Binding Proteins; Fever; Glutamine; Heat Shock Transcription Factors; Heat Stroke; HSP70 Heat-Shock Proteins; Humans; Intestinal Mucosa; Permeability; Rats; Survival Analysis; Transcription Factors | 2006 |
Glutamine inhibits lipopolysaccharide-induced cytoplasmic phospholipase A2 activation and protects against endotoxin shock in mouse.
Topics: Animals; Death; Disease Models, Animal; Endotoxins; Glutamine; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Phospholipases A; Phospholipases A2; Shock, Septic; Tumor Necrosis Factor-alpha | 2006 |
The metabolism of C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Brain; Brain Infarction; Brain Ischemia; Carbon Radioisotopes; Cell Communication; Cell Death; Disease Models, Animal; Down-Regulation; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Infarction, Middle Cerebral Artery; Male; Neurons; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
Influence of glutamine on pancreatic blood flow and apoptosis of pancreatic acinar in rats with severe acute pancreatitis.
Topics: Animals; Apoptosis; Disease Models, Animal; Glutamine; In Situ Nick-End Labeling; Mesenteric Artery, Superior; Pancreas; Pancreatitis, Acute Necrotizing; Portal Vein; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Severity of Illness Index; Splanchnic Circulation; Splenic Artery; Ultrasonography | 2006 |
The effect of glutamine on locomotor performance and skeletal muscle myosins following spinal cord injury in rats.
Topics: Animals; Disease Models, Animal; Exploratory Behavior; Foot; Glutamine; Laminectomy; Male; Motor Activity; Muscle, Skeletal; Myosin Heavy Chains; Protein Isoforms; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries | 2006 |
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Disease Models, Animal; Factor V; Ferric Compounds; Gene Frequency; Glutamine; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Thrombosis; Venous Thrombosis | 2007 |
Arginine-enriched diet limits plasma and muscle glutamine depletion in head-injured rats.
Topics: Animals; Arginine; Craniocerebral Trauma; Disease Models, Animal; Enteral Nutrition; Glutamine; Male; Muscle, Skeletal; Nutritional Requirements; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Neuronal atrophy and synaptic alteration in a mouse model of dentatorubral-pallidoluysian atrophy.
Topics: Animals; Atrophy; Axons; Cerebral Cortex; Corpus Callosum; Dendrites; Dendritic Spines; Disease Models, Animal; Glutamine; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Electron; Microtubules; Neurons; Peptides; Pyramidal Tracts; Spinocerebellar Degenerations; Synapses | 2006 |
Modulation of p53 and c-myc in DMBA-induced mammary tumors by oral glutamine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glutamine; Glutathione; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2006 |
Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine.
Topics: Adenosine; Adrenergic Agents; Alzheimer Disease; Amphetamine; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamine; Injections, Intraventricular; Male; Mice; Motor Activity; Psychotic Disorders | 2004 |
Brain metabolic markers reflect susceptibility status in cytokine gene knockout mice with murine cerebral malaria.
Topics: Animals; Brain; Cytokines; Disease Models, Animal; Disease Progression; Disease Susceptibility; Glucose; Glutamine; Magnetic Resonance Spectroscopy; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Mice, Knockout | 2006 |
[Effects of glutamine given through different avenues on intestine mucosal barrier function in burned rats].
Topics: Animals; Burns; Disease Models, Animal; Enteral Nutrition; Female; Glutamine; Intestinal Mucosa; Male; Parenteral Nutrition; Permeability; Random Allocation; Rats; Rats, Wistar | 2006 |
Protection elicited by two glutamine auxotrophs of Mycobacterium tuberculosis and in vivo growth phenotypes of the four unique glutamine synthetase mutants in a murine model.
Topics: Animals; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutamine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Mutation; Mycobacterium tuberculosis; Phenotype; Tuberculosis, Pulmonary | 2006 |
Accumulation of 99mTc-Cysteine in experimental inflammatory lesions in comparison to 99mTc-glutamine and 99mTc-HIG.
Topics: Animals; Arthritis, Experimental; Cysteine; Disease Models, Animal; Glutamine; Immunoglobulins; Inflammation; Knee Joint; Mice; Organotechnetium Compounds; Radionuclide Imaging; Technetium | 1997 |
Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy.
Topics: Action Potentials; Amino Acid Transport System A; Amino Acid Transport Systems; Animals; beta-Alanine; Brain Injuries; Cerebral Cortex; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy, Post-Traumatic; Evoked Potentials; Glutamic Acid; Glutamine; Organ Culture Techniques; Rats | 2007 |
Low intestinal glutamine level and low glutaminase activity in Crohn's disease: a rational for glutamine supplementation?
Topics: Adult; Animals; Case-Control Studies; Colon; Crohn Disease; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Female; Glutaminase; Glutamine; Glutathione; Humans; Ileitis; Ileum; Indomethacin; Intestinal Mucosa; Lipid Peroxidation; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Rectus Abdominis | 2006 |
[Effects of glutamine on matrix metalloproteinase-3 and tissue inhibitor of metalloproteinase-3 expressions in myocardium of rats with sepsis].
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Glutamine; Immunohistochemistry; In Situ Hybridization; Lipopolysaccharides; Male; Matrix Metalloproteinase 3; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sepsis; Time Factors; Tissue Inhibitor of Metalloproteinase-3 | 2006 |
Metformin therapy in a transgenic mouse model of Huntington's disease.
Topics: Age Factors; AMP-Activated Protein Kinases; Animals; Behavior, Animal; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glutamine; Huntington Disease; Hypoglycemic Agents; Male; Metformin; Mice; Mice, Transgenic; Motor Activity; Multienzyme Complexes; Protein Serine-Threonine Kinases; Sex Factors; Trinucleotide Repeats | 2007 |
Glutamine alone or combined with short-chain fatty acids fails to enhance gut adaptation after massive enterectomy in rats.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fatty Acids, Volatile; Glutamine; Intestinal Mucosa; Intestine, Small; Male; Random Allocation; Rats; Rats, Wistar; Short Bowel Syndrome | 2006 |
Intestinal intraluminal injection of glutamine increases trolox total equivalent antioxidant capacity (TEAC) in hepatic ischemia-reperfusion.
Topics: Animals; Antioxidants; Chromans; Disease Models, Animal; Glutamine; Intestine, Small; Liver; Male; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury | 2006 |
Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia.
Topics: Animals; Astrocytes; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Dopamine; Energy Metabolism; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neurons; Schizophrenia; Synaptic Vesicles | 2007 |
A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
Topics: Animals; Animals, Genetically Modified; Ataxin-7; Cell Death; Cells, Cultured; Disease Models, Animal; Drosophila; Dyskinesias; Glutamine; Humans; Intranuclear Inclusion Bodies; Longevity; Male; Mutation; Nerve Tissue Proteins; Neurons; Peptides; Phenotype; Rats; Spinocerebellar Ataxias; Threonine | 2007 |
Metabolic progression markers of neurodegeneration in the transgenic G93A-SOD1 mouse model of amyotrophic lateral sclerosis.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Aspartic Acid; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Superoxide Dismutase; Time Factors | 2007 |
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome.
Topics: Amino Acid Substitution; Animals; Arginine; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Genetic Diseases, Inborn; Glutamine; Humans; Immune Tolerance; Immunologic Deficiency Syndromes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Mutagenesis, Site-Directed | 2007 |
Does concomitant glucose and glutamine supplementation change the response of glutamine synthetase to fasting in healthy adult rats?
Topics: Animals; Dietary Supplements; Disease Models, Animal; Drug Synergism; Fasting; Female; Glucose; Glutamate-Ammonia Ligase; Glutamine; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Up-Regulation | 2007 |
Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kappaB pathway in an experimental model of colitis in the rat.
Topics: Acetic Acid; Animals; Biomarkers; Colitis; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Glutamine; Glutathione Peroxidase; Immunologic Factors; Male; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2007 |
Effects of glutamine supplementation on gut barrier, glutathione content and acute phase response in malnourished rats during inflammatory shock.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Bacterial Translocation; Blood Proteins; Dietary Supplements; Disease Models, Animal; Glutamine; Glutathione; Glycoproteins; Inflammatory Bowel Diseases; Intestinal Mucosa; Irritants; Liver; Male; Malnutrition; Orosomucoid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Turpentine | 2007 |
The effect of L-glutamine on mucosal healing in experimental colitis is superior to short-chain fatty acids.
Topics: Acids, Acyclic; Administration, Oral; Animals; Colitis; Disease Models, Animal; DNA; Enema; Glutamine; Intestinal Mucosa; Rats; Rats, Wistar; Regeneration; Wound Healing | 2007 |
Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure.
Topics: Ammonia; Animals; Brain Chemistry; Disease Models, Animal; Extracellular Space; Female; Glutamic Acid; Glutamine; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Sorption Detoxification; Swine | 2007 |
Astrocytes may play a role in the etiology of absence epilepsy: a comparison between immature GAERS not yet expressing seizures and adults.
Topics: Acetic Acid; Aging; Animals; Astrocytes; Brain; Cell Communication; Cell Differentiation; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Absence; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamine; Magnetic Resonance Spectroscopy; Male; Mitochondria; Neural Inhibition; Neurons; Rats; Up-Regulation | 2007 |
Changes in the rates of the tricarboxylic acid (TCA) cycle and glutamine synthesis in the monkey brain with hemiparkinsonism induced by intracarotid infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): studies by non-invasive 13C-magnetic reso
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Brain; Carbon Isotopes; Citric Acid Cycle; Disease Models, Animal; Dopamine; Female; Glutamine; Macaca fascicularis; Magnetic Resonance Spectroscopy; Parkinsonian Disorders | 2007 |
Effect of glutamine on gut glutathione fractional release in the implanted tumor model.
Topics: Amino Acids; Animals; Antioxidants; Disease Models, Animal; Electrolytes; Female; Glucose; Glutamine; Glutathione; Intestinal Mucosa; Intestines; Mammary Neoplasms, Experimental; Nutritional Status; Parenteral Nutrition Solutions; Random Allocation; Rats; Rats, Inbred F344; Solutions | 2007 |
Glutamine improves myocardial function following ischemia-reperfusion injury.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Disease Models, Animal; Drug Administration Schedule; Glutamine; Hemodynamics; Injections, Intraperitoneal; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley | 2007 |
Cerebral blood flow autoregulation in experimental liver failure.
Topics: Ammonia; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Glutamic Acid; Glutamine; Homeostasis; Intracranial Hypertension; Intracranial Pressure; Laser-Doppler Flowmetry; Liver Failure, Acute; Male; Models, Cardiovascular; Necrosis; Rats; Rats, Wistar; Water | 2008 |
Glutamine preferentially inhibits T-helper type 2 cell-mediated airway inflammation and late airway hyperresponsiveness through the inhibition of cytosolic phospholipase A(2) activity in a murine asthma model.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Cytokines; Disease Models, Animal; Eosinophils; Female; Glutamine; Mice; Mice, Inbred BALB C; Mucus; Neutrophils; Phospholipases A2, Cytosolic; Phosphorylation; Th2 Cells | 2008 |
Metabolic changes detected by proton magnetic resonance spectroscopy in vivo and in vitro in a murin model of Parkinson's disease, the MPTP-intoxicated mouse.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurochemistry; Neurotransmitter Agents; Parkinsonian Disorders; Protons; Substantia Nigra; Synaptic Transmission; Up-Regulation | 2008 |
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder.
Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Metabolomics; Middle Aged; Prefrontal Cortex; Rats; Rats, Inbred WKY; Reference Values | 2009 |
l-Glutamine administration reduces oxidized glutathione and MAP kinase signaling in dystrophic muscle of mdx mice.
Topics: Age Factors; Animals; Antioxidants; Body Weight; Dietary Supplements; Disease Models, Animal; Down-Regulation; Glutamine; Glutathione; Glutathione Disulfide; Injections, Intraperitoneal; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-kappa B; Oxidative Stress; Phosphorylation; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
Oral glutamine prevents DMBA-induced mammary carcinogenesis via upregulation of glutathione production.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Disease Models, Animal; Female; Glutamine; Glutathione; Killer Cells, Natural; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2008 |
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity.
Topics: Amphetamine; Animals; Antipsychotic Agents; Arousal; Brain; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glutamine; Injections, Intraperitoneal; Injections, Subcutaneous; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phenols; Psychotic Disorders; Receptors, Serotonin; Reflex, Startle; Sulfonamides; Synaptic Transmission | 2008 |
Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.
Topics: Animals; Arginine; Asparagine; Disease Models, Animal; Female; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Mice, Transgenic; Neuroprotective Agents; Nipecotic Acids; PC12 Cells; Rats; Tiagabine | 2008 |
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease.
Topics: Animals; Asparagine; Cell Differentiation; Cell Movement; Disease Models, Animal; Disease Progression; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Sertraline | 2008 |
Effect of glutaurine on liver tumour development and acute leukaemia induced by MC29 virus in turkey poults.
Topics: Animals; Avian Leukosis; Avian Leukosis Virus; Disease Models, Animal; Female; Glutamine; Liver Neoplasms, Experimental; Male; Poultry Diseases; RNA-Directed DNA Polymerase; Taurine; Turkeys | 1983 |
Metabolism and transport of L-glutamine and L-alanine by renal tubules of chickens.
Topics: Acidosis, Respiratory; Alanine; Alkalosis, Respiratory; Animals; Biological Transport; Carbon Dioxide; Chickens; Disease Models, Animal; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules; Lactates; Lactic Acid; Renal Circulation | 1983 |
Hepatocyte heterogeneity in ammonia metabolism: impairment of glutamine synthesis in CCl4 induced liver cell necrosis with no effect on urea synthesis.
Topics: Ammonia; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutamine; Liver Diseases; Male; Necrosis; Rats; Rats, Inbred Strains; Urea | 1984 |
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy.
Topics: Animals; Cell Death; Disease Models, Animal; Gliosis; Glutamic Acid; Glutamine; Hippocampus; Histamine; Histamine Release; Male; Methylhistidines; Microdialysis; Necrosis; Nerve Degeneration; Neuroglia; Pyrithiamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy | 1994 |
A diet producing a low diabetes incidence modifies immune abnormalities in diabetes-prone BB rats.
Topics: Animals; Autoimmune Diseases; Cells, Cultured; Diabetes Mellitus; Diet; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glutamine; Immune System; Immunophenotyping; Incidence; Killer Cells, Natural; Lymph Nodes; Lymphocytes; Male; Rats; Rats, Inbred BB; Spleen; Thymidine | 1995 |
Serial changes in metabolism and histology in the cold-injury trauma rat brain model--proton magnetic resonance imaging and spectroscopy study.
Topics: Acetates; Animals; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Cold Temperature; Disease Models, Animal; Female; Glutamine; Glycolysis; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mitochondria; Rats; Rats, Wistar | 1995 |
[Glutamine (Gln) supplementation in septic rats].
Topics: Animals; Disease Models, Animal; Female; Glutamine; Infections; Lymphocyte Activation; Male; Mononuclear Phagocyte System; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley | 1993 |
Effect of sodium benzoate on cerebral and hepatic energy metabolites in spf mice with congenital hyperammonemia.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Ammonia; Animals; Benzoates; Benzoic Acid; Brain; Coenzyme A; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Liver; Male; Mice; Mice, Mutant Strains; Ornithine Carbamoyltransferase Deficiency Disease; Time Factors; Urea | 1993 |
Effects of repeated cerebral ischemia on extracellular amino acid concentrations measured with intracerebral microdialysis in the gerbil hippocampus.
Topics: Amino Acids; Animals; Brain Ischemia; Disease Models, Animal; Extracellular Space; gamma-Aminobutyric Acid; Gerbillinae; Glutamine; Glycine; Hippocampus; Necrosis; Neurons; Taurine | 1993 |
Starvation and endotoxin act independently and synergistically to coordinate hepatic glutamine transport.
Topics: Amino Acids; Analysis of Variance; Animals; Bacteremia; Biological Transport; Disease Models, Animal; Escherichia coli Infections; Glutamine; In Vitro Techniques; Lipopolysaccharides; Liver; Male; Rats; Rats, Inbred F344; Starvation | 1996 |
Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse.
Topics: Ammonia; Animals; Brain Damage, Chronic; Disease Models, Animal; Glutamine; Hair; Metabolism, Inborn Errors; Mice; Mice, Inbred Strains; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Quinolinic Acid; Tryptophan | 1995 |
Ornithine-alpha-ketoglutarate (OKG) supplementation is more effective than its component salts in traumatized rats.
Topics: Amino Acids; Animals; Body Weight; Creatinine; Diet; Disease Models, Animal; Eating; Femoral Fractures; Food, Fortified; Glutamine; Glycine; Growth Hormone; Insulin; Ketoglutaric Acids; Male; Muscle, Skeletal; Nitrogen; Ornithine; Random Allocation; Rats; Rats, Sprague-Dawley; Urea; Wounds and Injuries | 1996 |
Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs.
Topics: Alanine; Animals; Aspartic Acid; Atrophy; Diet; Disease Models, Animal; Duodenum; Epithelium; Female; Glutamic Acid; Glutamine; Intestinal Diseases; Jejunum; Male; Stomach; Swine; Swine Diseases; Taurine; Weaning | 1996 |
Neuronal and glial handling of glutamate and glutamine during hypoosmotic stress: a biochemical and quantitative immunocytochemical analysis using the rat cerebellum as a model.
Topics: Animals; Cerebellum; Disease Models, Animal; Glutamic Acid; Glutamine; Immunohistochemistry; Male; Microscopy, Electron; Neuroglia; Rats; Rats, Sprague-Dawley; Stress, Physiological | 1996 |
Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitis.
Topics: Analysis of Variance; Animals; Body Weight; Colitis; Colon; Diet; Disease Models, Animal; Drug Administration Schedule; Female; Glutamine; Interleukin-8; Intestinal Mucosa; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 1997 |
Changes in brain organic osmolytes in experimental cerebral ischemia.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Magnetic Resonance Spectroscopy; Male; Methylamines; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine | 1998 |
A fly's eye view of Huntington's disease.
Topics: Animals; Disease Models, Animal; Drosophila melanogaster; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Nerve Tissue Proteins; Nuclear Proteins; Photoreceptor Cells, Invertebrate; Recombinant Proteins | 1998 |
Enteral glutamine does not enhance the effects of hepatocyte growth factor in short bowel syndrome.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; DNA; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Motility; Gastrostomy; Glutamine; Hepatocyte Growth Factor; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Reference Values; Short Bowel Syndrome | 1998 |
Intravenous glutamine or limited enteral feedings in piglets: amelioration of small intestinal disuse atrophy.
Topics: Animals; Atrophy; beta-Galactosidase; Dietary Fats; Dietary Proteins; Disease Models, Animal; Energy Intake; Enteral Nutrition; Glutamine; Ileum; Intestine, Small; Jejunum; Lactase; Parenteral Nutrition, Total; Sucrase; Swine | 1998 |
Different complex formations of dentatorubral-pallidoluysian atrophy (DRPLA) protein in human and rat neurons.
Topics: Aged; Animals; Atrophy; Brain Diseases; Cerebral Cortex; Dentate Gyrus; Disease Models, Animal; Disulfides; Globus Pallidus; Glutamine; Humans; Immunohistochemistry; Intracellular Fluid; Middle Aged; Nerve Tissue Proteins; Rats | 1998 |
Intravenous glutamine or short-chain fatty acids reduce central venous catheter infection in a model of total parenteral nutrition.
Topics: Animals; Bacterial Translocation; Catheterization, Central Venous; Catheters, Indwelling; Chi-Square Distribution; Disease Models, Animal; Fatty Acids, Volatile; Glutamine; Intestinal Mucosa; Parenteral Nutrition, Total; Rats; Rats, Wistar; Sepsis | 1999 |
Localized 15N NMR spectroscopy of rat brain by ISIS.
Topics: Acetates; Animals; Brain; Brain Mapping; Disease Models, Animal; Glutamine; Image Enhancement; Magnetic Resonance Spectroscopy; Male; Nitrogen Radioisotopes; Phantoms, Imaging; Rats; Rats, Wistar; Sensitivity and Specificity | 1999 |
Food deprivation and refeeding influence growth, nutrient retention and functional recovery of rats.
Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Capillary Permeability; Diet; Disease Models, Animal; Food; Glutamine; Growth; Intestinal Mucosa; Liver; Male; Muscles; Nitrogen; Rats; Rats, Wistar; Starvation; Weight Gain | 1999 |
Does glutamine reduce bacterial translocation? A study in two animal models with impaired gut barrier.
Topics: Animals; Bacterial Translocation; Colitis; Colon; Dietary Supplements; Disease Models, Animal; Electrophysiology; Glutamine; Male; Pancreatitis; Parenteral Nutrition; Rats; Rats, Sprague-Dawley; Sepsis | 1999 |
The role of glutamine in skeletal muscle ischemia/reperfusion injury in the rat hind limb model.
Topics: Animals; Creatine Kinase; Disease Models, Animal; Glutamic Acid; Glutamine; Glutathione; Hindlimb; Injections, Intraperitoneal; Ischemia; Lipid Peroxidation; Male; Muscle, Skeletal; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Random Allocation; Rats; Rats, Inbred Strains; Reperfusion Injury; Single-Blind Method; Time Factors | 1999 |
Huntington's disease. In reverse gear.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Gene Expression Regulation; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Mice; Nerve Tissue Proteins; Nuclear Proteins; Trinucleotide Repeats | 2000 |
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamine; Lactic Acid; Male; Pyruvic Acid; Quercetin; Rats; Rats, Sprague-Dawley | 2001 |
Glutamine ameliorates mechanical obstruction-induced intestinal injury.
Topics: Administration, Oral; Animals; Arginine; Cecum; Disease Models, Animal; Glutamine; Ileum; Intestinal Mucosa; Intestinal Obstruction; Intestine, Small; Male; Rats; Rats, Sprague-Dawley | 2001 |
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Body Weight; Brain Chemistry; Creatine; Dicarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Microdialysis; Motor Activity; Motor Neuron Disease; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Oxidative Stress; Psychomotor Performance; Pyrrolidines; Superoxide Dismutase | 2001 |
Protein hydrolysate vs free amino acid-based diets on the nutritional recovery of the starved rat.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Proteins; Disease Models, Animal; Enteral Nutrition; Glutamine; Growth; Intestinal Mucosa; Liver; Male; Muscles; Nitrogen; Protein Hydrolysates; Random Allocation; Rats; Rats, Wistar; Starvation; Weight Gain | 2000 |
Feeding a protective hydrolysed casein diet to young diabetic-prone BB rats affects oxidation of L[U-14C]glutamine in islets and Peyer's patches, reduces abnormally high mitotic activity in mesenteric lymph nodes, enhances islet insulin and tends to norma
Topics: Administration, Oral; Animal Feed; Animals; Blood Glucose; Caseins; Diabetes Mellitus, Type 1; Dietary Proteins; Disease Models, Animal; Female; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Lymph Nodes; Male; Mitosis; Nitric Oxide; Oxidation-Reduction; Peyer's Patches; Protein Hydrolysates; Rats; Rats, Inbred BB; Reference Values; Weight Gain | 2000 |
Glutamine transporter in crypts compensates for loss of villus absorption in bovine cryptosporidiosis.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Animals; Blotting, Western; Carrier Proteins; Cattle; Chlorides; Cryptosporidiosis; Cyclooxygenase Inhibitors; Dinoprostone; Dipeptides; Disease Models, Animal; Drug Synergism; Glutamine; Ileum; Immunohistochemistry; In Vitro Techniques; Indomethacin; Intestinal Absorption; Ion Transport; Sodium | 2001 |
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
Topics: Acetylation; Acetyltransferases; Animals; Animals, Genetically Modified; CREB-Binding Protein; Disease Models, Animal; Drosophila; Drosophila Proteins; E1A-Associated p300 Protein; Enzyme Inhibitors; Gene Expression Regulation; Glutamine; Glutathione Transferase; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Huntingtin Protein; Huntington Disease; Nerve Degeneration; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; PC12 Cells; Peptides; Protein Structure, Tertiary; Rats; Repetitive Sequences, Amino Acid; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Trans-Activators | 2001 |
Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia.
Topics: Animals; Cytokines; Disease Models, Animal; Endotoxemia; Escherichia coli; Glutamine; Ileum; Interleukin-1; Interleukin-10; Lipopolysaccharides; Lung; Male; Rats; Rats, Sprague-Dawley; Sepsis; Time Factors; Tumor Necrosis Factor-alpha | 2001 |
Bacterial translocation and glutamine.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Glutamine; Intestines; Rats; Treatment Outcome | 2002 |
Both glucose-insulin-potassium and glutamine in warm blood cardioplegia increase the rates of myocardial glucose and free fatty acid oxidation.
Topics: Animals; Blood Glucose; Body Temperature Regulation; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glutamine; Heart Arrest, Induced; Hemodynamics; Insulin; Linear Models; Male; Myocardium; Potassium; Random Allocation; Reference Values; Sensitivity and Specificity; Swine; Time Factors | 2002 |
Effects of an alanyl-glutamine-based oral rehydration and nutrition therapy solution on electrolyte and water absorption in a rat model of secretory diarrhea induced by cholera toxin.
Topics: Animals; Cholera Toxin; Diarrhea; Dipeptides; Disease Models, Animal; Electrolytes; Female; Fluid Therapy; Glutamine; Intestinal Absorption; Kinetics; Male; Potassium; Rats; Rats, Wistar; Rehydration Solutions; Sodium; Water | 2002 |
Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig.
Topics: Acidosis; Alanine; Amino Acids; Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutamic Acid; Glutamine; Injections, Intravenous; Ketoglutaric Acids; Male; Muscle, Skeletal; Quaternary Ammonium Compounds; Random Allocation; Splanchnic Circulation; Swine; Urea; Viscera | 2002 |
Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase.
Topics: Aldehyde Oxidoreductases; Animals; beta-Alanine; Blotting, Western; Brain; Carboxylic Acids; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamine; Kidney; Liver; Male; Mice; Mice, Knockout; Myocardium; Organ Specificity; Oxidation-Reduction; Pancreas; RNA, Messenger; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase | 2002 |
Inhibitors of gastric lesions in the rat.
Topics: Animals; Aspirin; Disease Models, Animal; Female; Glutamine; Histamine Antagonists; Indomethacin; Ligation; Pylorus; Rats; Salicylates; Stomach Ulcer; Stress, Physiological | 1978 |
Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamates; Glutamine; Ketoglutaric Acids; Penicillins; Pyruvates; Rats; Seizures; Time Factors; Transaminases | 1978 |
Effect of supplemental dietary glutamine on methotrexate concentrations in tumors.
Topics: Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Energy Intake; Glutamine; Humans; Male; Methotrexate; Rats; Rats, Inbred F344; Sarcoma, Experimental | 1992 |
Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Flow Velocity; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutamates; Glutamic Acid; Glutamine; Hematoma, Subdural; Male; Rats; Rats, Inbred Strains; Regression Analysis; Valine | 1991 |
High-performance liquid chromatographic determination of selected amino acids in rat brain by precolumn derivatization with phenylisothiocyanate.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Isothiocyanates; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Thiocyanates | 1990 |
Effect of a new cholecystokinin receptor antagonist loxiglumide on acute pancreatitis in two experimental animal models.
Topics: Acute Disease; Animals; Ceruletide; Cholecystokinin; Disease Models, Animal; Glutamine; Male; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Taurocholic Acid | 1990 |
Oral glutamine accelerates healing of the small intestine and improves outcome after whole abdominal radiation.
Topics: Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Enteritis; Glutamine; Glycine; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains | 1990 |
[Neurotropic fungal metabolites].
Topics: Animals; Disease Models, Animal; Dopamine Agents; Epilepsy; Glutamine; Mice; Mycotoxins; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Nephritogenic glycoprotein. XII. Focal glomerulonephritis with myeloid bodies produced in rats by synthetic analogues of the glycopeptide, nephritogenoside.
Topics: Animals; Asparagine; Cells, Cultured; Disease Models, Animal; Fluorescent Antibody Technique; Glomerulonephritis; Glutamine; Glycopeptides; Humans; Inclusion Bodies; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred Strains; Trisaccharides | 1987 |
A possible drug interaction between aspirin and L-glutamine on some experimental inflammatory and analgesic models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; Drug Interactions; Female; Glutamine; Inflammation; Male; Mice; Mice, Inbred Strains; Pain; Rats | 1988 |
Experimental acute pancreatitis induced by excessive doses of caerulein in rats; protective and therapeutic effects of trypsin inhibitor urinastatin and CCK receptor antagonist CR1392.
Topics: Acute Disease; Animals; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Glycoproteins; Kinetics; Male; Microscopy, Electron; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Trypsin Inhibitors | 1988 |
[Enzymes of glutamine metabolism in the brain in acute hypoxic hypoxia].
Topics: Acute Disease; Animals; Brain; Brain Chemistry; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Hypoxia, Brain; Rabbits; Transaminases | 1973 |
Renal ammoniagenesis and tissue glutamine, glutamine synthetase, and glutaminase I levels in potassium-deficient rats.
Topics: Ammonia; Animals; Carbon Dioxide; Chlorides; Disease Models, Animal; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kidney; Liver; Male; Muscles; Organ Size; Potassium; Potassium Deficiency; Rats; Renal Veins; Sodium | 1973 |
Ultrastructural responses of the astrocytes to portocaval anastomosis in the rat.
Topics: Ammonia; Animals; Brain; Brain Diseases; Carbon Tetrachloride Poisoning; Caudate Nucleus; Cerebellar Nuclei; Chemical and Drug Induced Liver Injury; Cytoplasm; Disease Models, Animal; Glutamates; Glutamine; Liver Diseases; Male; Microscopy, Electron; Nerve Degeneration; Nerve Fibers, Myelinated; Neuroglia; Nitrosamines; Portacaval Shunt, Surgical; Rats | 1973 |
Therapeutic properties of a new glutaminase-asparaginase preparation and the influence of the lactate dehydrogenase-elevating virus.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamates; Glutaminase; Glutamine; Half-Life; Hydrogen-Ion Concentration; Isoelectric Focusing; L-Lactate Dehydrogenase; Leukemia, Experimental; Mice; Mice, Inbred C57BL; RNA Viruses | 1974 |
Abnormal orotic acid metabolism associated with acute hyperammonaemia in the rat.
Topics: Acetates; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Disease Models, Animal; Electrophoresis, Paper; Glutamates; Glutamine; Hydrogen-Ion Concentration; Liver; Male; Mass Spectrometry; Orotic Acid; Pentosyltransferases; Purine Nucleotides; Quaternary Ammonium Compounds; Rats; Time Factors; Uracil Nucleotides | 1974 |
Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.
Topics: Acid-Base Equilibrium; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Carbohydrate Metabolism; Carbon Dioxide; Citrates; Disease Models, Animal; Glucose; Glutamates; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Nucleotidases; Oxidation-Reduction; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1974 |
Cerebral metabolic state following complete compression ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Aspartic Acid; Blood Pressure; Carbohydrate Metabolism; Carbon Dioxide; Cerebral Cortex; Citric Acid Cycle; Disease Models, Animal; Electroencephalography; Glucose; Glutamine; Hydrogen-Ion Concentration; Intracranial Pressure; Ischemic Attack, Transient; Ketoglutaric Acids; Lactates; Malates; Mitochondria; Nucleotidases; Oxygen; Partial Pressure; Phosphocreatine; Pyruvates; Rats; Time Factors | 1974 |
Phenylketonuria and glutamine.
Topics: Animals; Disease Models, Animal; Glutamine; Haplorhini; Humans; Intellectual Disability; Phenylketonurias; Rats | 1970 |
Renal metabolism of glutamine in dogs during infusion of -ketoglutaric acid.
Topics: Acidosis; Ammonia; Ammonium Chloride; Animals; Cell Membrane Permeability; Disease Models, Animal; Dogs; Female; Glutaminase; Glutamine; Ketoglutaric Acids; Kidney; Male; Membranes; Mitochondria; Permeability | 1972 |
Phenylketonuria and glutamine.
Topics: Animals; Disease Models, Animal; Female; Glutamates; Glutamine; Humans; Infant, Newborn; Intellectual Disability; Phenylketonurias; Placenta; Pregnancy; Rats | 1970 |