glutamine and Depressive Disorder, Major

glutamine has been researched along with Depressive Disorder, Major in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (23.33)	29.6817
2010's	32 (53.33)	24.3611
2020's	14 (23.33)	2.80

Authors

Authors	Studies
Cai, H; Cao, T; Chen, Q; Jiao, S; Wang, L; Wu, X; Yang, C; Yang, D; Yang, P; Zeng, C; Zhang, S; Zhu, Z	1
Barredo, J; Carpenter, LL; Fukuda, AM; Gonsalves, MA; Harris, AD; Joyce, HE; White, TL	1
Barbini, B; Benedetti, F; Bravi, B; Dallaspezia, S; Melloni, EMT; Poletti, S; Zanardi, R	1
Allauze, E; Chabert, J; Chassain, C; De Chazeron, I; Fossati, P; Llorca, PM; Pereira, B; Rotgé, JY; Samalin, L	1
Ban, M; He, J; Kong, L; Wang, D; Xiao, Q; Yuan, F; Zhu, X	1
Bi, Y; Chen, Y; He, R; Li, M; Lin, H; Lu, J; Ning, G; Wang, S; Wang, T; Wang, W; Xu, M; Xu, Y; Zhao, Z; Zheng, J; Zheng, R	1
Pavlova, I; Ruda-Kucerova, J	1
Boeker, H; Ernst, J; Grimm, S; Lehmann, M; Richter, A; Seifritz, E; Wade-Bohleber, L; Zoelch, N	1
de Diego-Adeliño, J; Draganov, M; Portella, MJ; Puigdemont, D; Vicent-Gil, M; Vives-Gilabert, Y	1
Atalay, S; Cummings, A; Ding, XQ; Frieling, H; Kahl, KG; Lanfermann, H; Maudsley, AA; Schmitz, B; Sheriff, S	1
Alvarez-Vazquez, C; Gonzalez-Blanco, L; Jimenez-Trevino, L; Rodriguez-Revuelta, J; Saiz Martinez, PA	1
Cheng, PZ; Duncan, NW; Hsu, TY; Lane, TJ; Lee, HC; Truong, V	1
Badamasi, IM; Ibrahim, N; Lye, MS; Maulidiani, M; Shaari, K; Stanslas, J	1
Aryutova, K; Kandilarova, S; Paunova, R; Stoyanov, D; Todeva-Radneva, A	1
Chen, JX; Ding, XF; Jiao, HY; Li, YH; Sun, LJ; Wang, XX; Zhou, Y	1
Bradley, KA; Gabbay, V; Kang, G; Mao, X; Ostrover, R; Shungu, DC	1
Cowen, PJ; Emir, UE; Godlewska, BR; Masaki, C; Sharpley, AL	1
Arnone, D; Cappello, F; Cleare, AJ; Gammazza, AM; Herane-Vives, A; Lythgoe, DJ; Taylor, MJ; Williams, SC; Wise, T; Young, AH	1
Hara, A; Okubo, T; Osone, F; Shirayama, Y; Takahashi, M	1
An, L; Banerjee, D; Evans, JW; Lally, N; Li, N; Nugent, AC; Roiser, JP; Shen, J; Snider, SL; Zarate, CA	1
Forman, J; Kessing, LV; Knorr, U; Pech, J	1
Chea, W; Gardner, AC; Godfrey, KEM; Kwon, S; Muthukumaraswamy, SD	1
Blumberger, DM; Daskalakis, ZJ; ElSalhy, M; Graff-Guerrero, A; Horita, N; Katayama, N; Kishimoto, T; Meyer, JH; Mimura, M; Miyazaki, T; Moriguchi, S; Nakajima, S; Noda, Y; Ogyu, K; Plitman, E; Sano, Y; Takamiya, A; Tarumi, R; Tsugawa, S; Wada, M	1
Colic, L; Demenescu, LR; Denzel, D; Frommer, J; Kaufmann, J; Li, M; Lison, S; Lord, AR; Martens, L; Speck, O; Vogel, M; von Düring, F; Walter, M	1
Brechbühl, S; Buchmann, A; Ghisleni, C; Hasler, G; Haynes, M; Müller, ST; Tuura, R	1
Álvarez, E; de Diego-Adeliño, J; Gómez-Ansón, B; López-Moruelo, O; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Serra-Blasco, M; Vives, Y	1
Chen, LP; Dai, HY; Dai, ZZ; Wu, RH; Xu, CT	1
Taylor, MJ	1
Cooper, TB; Kegeles, LS; Keilp, JG; Mann, JJ; Mao, X; Milak, MS; Mulhern, ST; Ogden, RT; Oquendo, MA; Parter, AL; Proper, CJ; Rodriguez, CI; Shungu, DC; Suckow, RF	1
Hamazaki, K; Hamazaki, T; Hashimoto, K; Matsuoka, Y; Nishi, D; Noguchi, H	1
Banerjee, S; Dubin, MJ; Goodman, Z; Kang, G; Lapidus, KA; Liston, C; Mao, X; Shungu, DC	1
Blennow, K; Bruno, D; Hashimoto, K; Marmar, CR; Nierenberg, J; Pomara, N; Zetterberg, H	1
Li, Y; Maletic-Savatic, M; Sheng, J; Tang, Y; Tong, S; Wang, J; Zhang, T; Zhang, X; Zhu, Y	1
Biswal, B; Colic, L; Demenescu, LR; Li, M; Li, S; Metzger, CD; Safron, A; Walter, M	1
Guan, JT; Guo, XB; Li, H; Liu, CF; Ou, SM; Shen, ZW; Tan, HZ; Wang, XQ; Wen, CH; Wu, RH; Xu, CT; Zhang, J; Zhang, YN	1
Cho, H; Kim, CH; Kim, DG; Kim, GT; Seo, J	1
Auer, DP; Murck, H; Schmid, D; Schubert, MI; Schüssler, P; Steiger, A	1
Block, W; Jessen, F; Maier, W; Metten, M; Schild, H; Träber, F; von Widdern, O; Zobel, A	1
Charney, DS; Collins, KA; Kelly, C; Mao, X; Mathew, SJ; Murrough, JW; Nestadt, P; Price, RB; Shungu, DC	1
Hall, GB; MacQueen, GM; Milne, A; Soreni, N; Yucel, K	1
Beck, J; Boeker, H; Boesiger, P; Dydak, U; Grimm, S; Henning, A; Northoff, G; Schnepf, B; Schulte, RF; Walter, M	1
Cowen, PJ; Jezzard, P; Murphy, S; Norbury, R; Rudebeck, S; Taylor, MJ	1
Caetano, SC; Chen, HH; Hatch, JP; Matsuo, K; Monkul, ES; Najt, P; Nery, FG; Nicoletti, MA; Peluso, MA; Soares, JC; Stanley, JA	1
Austin, MC; Miguel-Hidalgo, JJ; Rajkowska, G; Stockmeier, CA; Waltzer, R; Whittom, AA	1
Cowen, PJ; Mannie, ZN; Near, J; Norbury, R; Taylor, MJ	1
Anttila, S; Huuhka, M; Illi, A; Kampman, O; Lehtimäki, T; Leinonen, E; Mononen, N; Setälä-Soikkeli, E; Viikki, M	1
Bird, TD; Ghetti, B; Jayadev, S; Leverenz, JB; Mastrianni, JA; Montine, TJ; Nochlin, D; Poorkaj, P; Schellenberg, GD; Steinbart, EJ	1
Cowen, PJ; Mhuircheartaigh, RN; Taylor, MJ; Tiangga, ER	1
Baumann, J; Drevets, WC; Ibrahim, LA; Luckenbaugh, DA; Machado-Vieira, R; Marenco, S; Salvadore, G; Shen, J; van der Veen, JW; Zarate, CA; Zhang, Y	1
Garakani, A; Gorman, JM; Martinez, JM; Yehuda, R	1
Owen, RT	1
Berk, M; Das, P; Dean, OM; Dodd, S; Fritz, K; Malhi, GS; Tanious, M	1
Arolt, V; Erfurth, A; Heindel, W; Michael, N; Ohrmann, P; Pfleiderer, B	1
Banerjee, SP; Bhandari, R; Boyd, C; Ivey, J; Mirza, Y; Moore, GJ; Rose, M; Rosenberg, DR; Russell, A; Smith, JM; Tang, J	1
Caetano, SC; Fonseca, M; Hatch, JP; Hunter, K; Lafer, B; Nicoletti, M; Olvera, RL; Pliszka, SR; Soares, JC; Stanley, JA	1
Bain, EE; Charney, DS; Drevets, WC; Hasler, G; Neumeister, A; Shen, J; Tumonis, T; van der Veen, JW	1
Banerjee, SP; Bhandari, R; Boyd, C; Easter, PC; Ivey, J; Lynch, M; Macmaster, FP; Mirza, Y; Moore, GJ; Renshaw, P; Rose, M; Rosenberg, DR; Smith, JM; Villafuerte, RA	1
Ajilore, O; Binesh, N; Darwin, C; Haroon, E; Kumar, A; Kumaran, S; Miller, J; Mintz, J; Thomas, MA	1
Drevets, WC; Hasler, G; Meyers, N; Shen, J; Tumonis, T; van der Veen, JW	1
Auer, DP; Holsboer, F; Kraft, E; Lipinski, B; Pütz, B; Schill, J	1

Reviews

10 review(s) available for glutamine and Depressive Disorder, Major

Article	Year
Repetitive Transcranial Magnetic Stimulation-Associated Changes in Neocortical Metabolites in Major Depression: A Systematic Review. NeuroImage. Clinical, 2022, Volume: 35 Topics: Depression; Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Neocortex; Prefrontal Cortex; Transcranial Magnetic Stimulation; Treatment Outcome	2022
Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies. International journal of molecular sciences, 2022, Aug-11, Volume: 23, Issue:16 Topics: Aspartic Acid; Bipolar Disorder; Depressive Disorder, Major; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy	2022
Brain metabolic derangements examined using Progress in neuro-psychopharmacology & biological psychiatry, 2023, 12-20, Volume: 127 Topics: Animals; Aspartic Acid; Brain; Depression; Depressive Disorder, Major; Glutamic Acid; Glutamine; Proton Magnetic Resonance Spectroscopy; Rodentia	2023
Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis. Psychiatry research. Neuroimaging, 2021, 02-28, Volume: 308 Topics: Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging	2021
The Translational Potential of Non-coding RNAs and Multimodal MRI Data Sets as Diagnostic and Differential Diagnostic Biomarkers for Mood Disorders. Current topics in medicinal chemistry, 2021, Volume: 21, Issue:11 Topics: Biomarkers; Bipolar Disorder; Brain; Depressive Disorder, Major; Gene Expression Regulation; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; MicroRNAs; Mood Disorders; RNA, Untranslated	2021
Poor evidence for putative abnormalities in cerebrospinal fluid neurotransmitters in patients with depression versus healthy non-psychiatric individuals: A systematic review and meta-analyses of 23 studies. Journal of affective disorders, 2018, Volume: 240 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neurotransmitter Agents; Young Adult	2018
Differences in excitatory and inhibitory neurotransmitter levels between depressed patients and healthy controls: A systematic review and meta-analysis. Journal of psychiatric research, 2018, Volume: 105 Topics: Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Prefrontal Cortex	2018
Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies. Molecular psychiatry, 2019, Volume: 24, Issue:7 Topics: Adolescent; Adult; Aged; Aspartic Acid; Depression; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Synaptic Transmission	2019
Could glutamate spectroscopy differentiate bipolar depression from unipolar? Journal of affective disorders, 2014, Volume: 167 Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Diagnosis, Differential; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity	2014
Glutamatergic approaches in major depressive disorder: focus on ketamine, memantine and riluzole. Drugs of today (Barcelona, Spain : 1998), 2012, Volume: 48, Issue:7 Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Glutamine; Humans; Ketamine; Memantine; Riluzole; Treatment Outcome	2012

Trials

7 trial(s) available for glutamine and Depressive Disorder, Major

Article	Year
7T Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:9 Topics: Adult; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Female; Glutamic Acid; Glutamine; Humans; Ketamine; Male; Proton Magnetic Resonance Spectroscopy	2018
Anterior cingulate cortex and cerebellar hemisphere neurometabolite changes in depression treatment: A 1H magnetic resonance spectroscopy study. Psychiatry and clinical neurosciences, 2014, Volume: 68, Issue:5 Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Cerebellum; Choline; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult	2014
Glutamatergic system abnormalities in posttraumatic stress disorder. Psychopharmacology, 2015, Volume: 232, Issue:23 Topics: Adult; Biomarkers; Case-Control Studies; Depressive Disorder, Major; Double-Blind Method; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Stress Disorders, Post-Traumatic	2015
The glutamatergic system and its relation to the clinical effect of therapeutic-sleep deprivation in depression - an MR spectroscopy study. Journal of psychiatric research, 2009, Volume: 43, Issue:3 Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Choline; Creatine; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Parietal Lobe; Prefrontal Cortex; Psychiatric Status Rating Scales; Sex Factors; Sleep Deprivation; Treatment Outcome	2009
Lack of effect of citalopram on magnetic resonance spectroscopy measures of glutamate and glutamine in frontal cortex of healthy volunteers. Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:8 Topics: Adult; Citalopram; Depressive Disorder, Major; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Software; Young Adult	2010
Metabolite profiles in the anterior cingulate cortex of depressed patients differentiate those taking N-acetyl-cysteine versus placebo. The Australian and New Zealand journal of psychiatry, 2013, Volume: 47, Issue:4 Topics: Acetylcysteine; Aspartic Acid; Depressive Disorder, Major; Double-Blind Method; Female; Free Radical Scavengers; Functional Neuroimaging; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Oxidative Stress	2013
Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients. Neuroscience letters, 2005, Aug-26, Volume: 384, Issue:3 Topics: Adolescent; Child; Choline; Depressive Disorder, Major; Female; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons	2005

Other Studies

43 other study(ies) available for glutamine and Depressive Disorder, Major

Article	Year
Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts. European archives of psychiatry and clinical neuroscience, 2022, Volume: 272, Issue:7 Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers; Depressive Disorder, Major; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Norepinephrine; Serotonin; Tryptophan; Vanilmandelic Acid	2022
Antidepressant chronotherapeutics normalizes prefrontal Progress in neuro-psychopharmacology & biological psychiatry, 2022, 12-20, Volume: 119 Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Drug Chronotherapy; Glutamic Acid; Glutamine; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2022
Regional metabolic heterogeneity in anterior cingulate cortex in major depressive disorder: A multi-voxel Journal of affective disorders, 2022, 12-01, Volume: 318 Topics: Aspartic Acid; Depressive Disorder, Major; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Young Adult	2022
Causal Association Between Obesity, Circulating Glutamine Levels, and Depression: A Mendelian Randomization Study. The Journal of clinical endocrinology and metabolism, 2023, 05-17, Volume: 108, Issue:6 Topics: Anhedonia; Body Mass Index; Causality; Depression; Depressive Disorder, Major; Genome-Wide Association Study; Glutamine; Humans; Mendelian Randomization Analysis; Obesity; Polymorphism, Single Nucleotide	2023
Effects of Psychotherapy on Glutamatergic Neurotransmission. Neuropsychobiology, 2023, Volume: 82, Issue:4 Topics: Depressive Disorder, Major; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Psychotherapy, Psychodynamic; Synaptic Transmission	2023
Glutamatergic and GABA-ergic abnormalities in First-episode depression. A 1-year follow-up 1H-MR spectroscopic study. Journal of affective disorders, 2020, 04-01, Volume: 266 Topics: Depression; Depressive Disorder, Major; Follow-Up Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2020
Altered neurometabolism in major depressive disorder: A whole brain Progress in neuro-psychopharmacology & biological psychiatry, 2020, 07-13, Volume: 101 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Young Adult	2020
Glutamine and New Pharmacological Targets to Treat Suicidal Ideation. Current topics in behavioral neurosciences, 2020, Volume: 46 Topics: Bipolar Disorder; Depressive Disorder, Major; Glutamine; Humans; Suicidal Ideation; Suicide	2020
A Preliminary Nuclear Magnetic Resonance Metabolomics Study Identifies Metabolites that Could Serve as Diagnostic Markers of Major Depressive Disorder. Current neuropharmacology, 2022, Volume: 20, Issue:5 Topics: Acetone; Alanine; Biomarkers; Choline; Creatinine; Depressive Disorder, Major; Fatty Acids; Glutamine; Humans; Lactates; Magnetic Resonance Spectroscopy; Metabolomics; Valine	2022
Involvement of the glutamate/glutamine cycle and glutamate transporter GLT-1 in antidepressant-like effects of Xiao Yao san on chronically stressed mice. BMC complementary and alternative medicine, 2017, Jun-19, Volume: 17, Issue:1 Topics: Animals; Antidepressive Agents; China; Depressive Disorder, Major; Drugs, Chinese Herbal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Glutamine; Humans; Male; Mice	2017
Anterior cingulate cortex γ-aminobutyric acid deficits in youth with depression. Translational psychiatry, 2017, 08-22, Volume: 7, Issue:8 Topics: Adolescent; Anhedonia; Brain; Child; Depression; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Young Adult	2017
Brain glutamate in medication-free depressed patients: a proton MRS study at 7 Tesla. Psychological medicine, 2018, Volume: 48, Issue:10 Topics: Adolescent; Adult; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Middle Aged; Occipital Lobe; Proton Magnetic Resonance Spectroscopy; Putamen; Young Adult	2018
Glutamatergic hypofunction in medication-free major depression: Secondary effects of affective diagnosis and relationship to peripheral glutaminase. Journal of affective disorders, 2018, Volume: 234 Topics: Adult; Case-Control Studies; Depressive Disorder, Major; Female; Glutamic Acid; Glutaminase; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult	2018
Myo-inositol, Glutamate, and Glutamine in the Prefrontal Cortex, Hippocampus, and Amygdala in Major Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging, 2017, Volume: 2, Issue:2 Topics: Adult; Amygdala; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Temporal Lobe	2017
Rostral Anterior Cingulate Glutamine/Glutamate Disbalance in Major Depressive Disorder Depends on Symptom Severity. Biological psychiatry. Cognitive neuroscience and neuroimaging, 2019, Volume: 4, Issue:12 Topics: Adult; Anhedonia; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Severity of Illness Index	2019
Association between prefrontal glutamine levels and neuroticism determined using proton magnetic resonance spectroscopy. Translational psychiatry, 2019, 06-18, Volume: 9, Issue:1 Topics: Adult; Anxiety Disorders; Cross-Sectional Studies; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Neuroticism; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Young Adult	2019
Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden. Journal of psychiatry & neuroscience : JPN, 2013, Volume: 38, Issue:2 Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Cost of Illness; Cross-Sectional Studies; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged	2013
A pilot in vivo proton magnetic resonance spectroscopy study of amino acid neurotransmitter response to ketamine treatment of major depressive disorder. Molecular psychiatry, 2016, Volume: 21, Issue:3 Topics: Adult; Amino Acids; Antidepressive Agents; Brain; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance Imaging; Male; Middle Aged; Neurotransmitter Agents; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Tritium	2016
Elevated prefrontal cortex GABA in patients with major depressive disorder after TMS treatment measured with proton magnetic resonance spectroscopy. Journal of psychiatry & neuroscience : JPN, 2016, Volume: 41, Issue:3 Topics: Adult; Aged; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Transcranial Magnetic Stimulation; Treatment Outcome; Young Adult	2016
Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study. Translational psychiatry, 2016, Mar-01, Volume: 6 Topics: Aged; Aging; Chromatography, High Pressure Liquid; Cognition; Depressive Disorder, Major; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Male; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	2016
Altered neuronal spontaneous activity correlates with glutamate concentration in medial prefrontal cortex of major depressed females: An fMRI-MRS study. Journal of affective disorders, 2016, Sep-01, Volume: 201 Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Neurons; Prefrontal Cortex; Psychiatric Status Rating Scales	2016
A spectroscopic approach toward depression diagnosis: local metabolism meets functional connectivity. European archives of psychiatry and clinical neuroscience, 2017, Volume: 267, Issue:2 Topics: Adult; Cerebral Cortex; Connectome; Creatine; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged	2017
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders. Scientific reports, 2016, 11-21, Volume: 6 Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Glutamine; Gray Matter; Humans; Inositol; Organ Specificity	2016
Glutamatergic stimulation of the left dentate gyrus abolishes depressive-like behaviors in a rat learned helplessness paradigm. NeuroImage, 2017, 10-01, Volume: 159 Topics: Adaptation, Psychological; Animals; Dentate Gyrus; Depressive Disorder, Major; Glutamine; Helplessness, Learned; Rats; Stress, Psychological	2017
Proton MR spectroscopy of the hippocampus at 3 T in patients with unipolar major depressive disorder: correlates and predictors of treatment response. The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:3 Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Statistics, Nonparametric; Young Adult	2009
Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder. Biological psychiatry, 2009, May-01, Volume: 65, Issue:9 Topics: Adult; Brain; Case-Control Studies; Depressive Disorder, Major; Drug Resistance; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurotransmitter Agents; Occipital Lobe	2009
Hippocampal metabolic abnormalities at first onset and with recurrent episodes of a major depressive disorder: a proton magnetic resonance spectroscopy study. NeuroImage, 2009, Aug-01, Volume: 47, Issue:1 Topics: Adult; Analysis of Variance; Aspartic Acid; Choline; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Organ Size; Protons; Recurrence	2009
The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression. Archives of general psychiatry, 2009, Volume: 66, Issue:5 Topics: Adult; Arousal; Aspartic Acid; Blood Glucose; Corpus Callosum; Depressive Disorder, Major; Dominance, Cerebral; Emotions; Energy Metabolism; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Oxygen Consumption; Synaptic Transmission	2009
Normal metabolite levels in the left dorsolateral prefrontal cortex of unmedicated major depressive disorder patients: a single voxel (1)H spectroscopy study. Psychiatry research, 2009, Dec-30, Volume: 174, Issue:3 Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Case-Control Studies; Chi-Square Distribution; Creatine; Depressive Disorder, Major; Female; Functional Laterality; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex; Protons; Psychiatric Status Rating Scales; Young Adult	2009
Glial and glutamatergic markers in depression, alcoholism, and their comorbidity. Journal of affective disorders, 2010, Volume: 127, Issue:1-3 Topics: Adult; Aged; Alcoholism; Astrocytes; Comorbidity; Depressive Disorder, Major; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Frontal Lobe; Glial Fibrillary Acidic Protein; Glutamate Plasma Membrane Transport Proteins; Glutamate-Ammonia Ligase; Glutamine; Humans; Male; Middle Aged; Prefrontal Cortex; Reference Values; Synaptic Transmission	2010
Elevated cortical glutamate in young people at increased familial risk of depression. The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:2 Topics: Adolescent; Cerebral Cortex; Depression; Depressive Disorder; Depressive Disorder, Major; Family; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Risk Factors; Young Adult	2011
P2RX7 polymorphisms Gln460Arg and His155Tyr are not associated with major depressive disorder or remission after SSRI or ECT. Neuroscience letters, 2011, Apr-15, Volume: 493, Issue:3 Topics: Adult; Aged; Arginine; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Purinergic P2X7; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Tyrosine	2011
Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype. Annals of neurology, 2011, Volume: 69, Issue:4 Topics: Adult; Aged; Alzheimer Disease; Codon, Nonsense; Depressive Disorder, Major; Female; Glutamine; Humans; Memory Disorders; Memory, Short-Term; Middle Aged; Neurofibrillary Tangles; Neuropsychological Tests; Phenotype; Prion Diseases; Prion Proteins; Prions; tau Proteins; Tyrosine	2011
Lack of effect of ketamine on cortical glutamate and glutamine in healthy volunteers: a proton magnetic resonance spectroscopy study. Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:5 Topics: Adult; Cerebral Cortex; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Young Adult	2012
An investigation of amino-acid neurotransmitters as potential predictors of clinical improvement to ketamine in depression. The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:8 Topics: Adult; Cerebral Cortex; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurotransmitter Agents; Predictive Value of Tests; Psychiatric Status Rating Scales; Retrospective Studies	2012
Cerebrospinal fluid levels of glutamate and corticotropin releasing hormone in major depression before and after treatment. Journal of affective disorders, 2013, Apr-05, Volume: 146, Issue:2 Topics: Adult; Antidepressive Agents; Case-Control Studies; Corticotropin-Releasing Hormone; Cyclohexanols; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Suicidal Ideation; Treatment Outcome; Venlafaxine Hydrochloride; Young Adult	2013
Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression. Psychological medicine, 2003, Volume: 33, Issue:7 Topics: Aged; Brain Mapping; Depressive Disorder, Major; Dominance, Cerebral; Electroconvulsive Therapy; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Reference Values	2003
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls. Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:9 Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder; Personality Assessment; Phosphocreatine; Reference Values; Synaptic Transmission	2004
Normal prefrontal gamma-aminobutyric acid levels in remitted depressed subjects determined by proton magnetic resonance spectroscopy. Biological psychiatry, 2005, Dec-15, Volume: 58, Issue:12 Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales	2005
Reduced anterior cingulate glutamate in pediatric major depression: a magnetic resonance spectroscopy study. Biological psychiatry, 2005, Nov-01, Volume: 58, Issue:9 Topics: Adolescent; Brain Chemistry; Depressive Disorder, Major; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male	2005
Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disorder, Major; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales	2007
Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy. Archives of general psychiatry, 2007, Volume: 64, Issue:2 Topics: Adult; Ambulatory Care; Cell Count; Cross-Sectional Studies; Depressive Disorder, Major; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Prefrontal Cortex	2007
Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study. Biological psychiatry, 2000, Feb-15, Volume: 47, Issue:4 Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Frontal Lobe; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myo-Inositol-1-Phosphate Synthase; Severity of Illness Index	2000