glutamine has been researched along with Degenerative Diseases, Central Nervous System in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (7.14) | 18.2507 |
| 2000's | 17 (40.48) | 29.6817 |
| 2010's | 15 (35.71) | 24.3611 |
| 2020's | 7 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
| Al Khleifat, A; Al-Chalabi, A; Amouyel, P; Andersen, PM; Assialioui, A; Ataulina, A; Baird, D; Bakker, MK; Bakker, OB; Baloh, RH; Barthel, T; Başak, N; Beghi, E; Bell, S; Bensimon, G; Benyamin, B; Blair, IP; Braun, A; Breen, G; Brenner, D; Brice, A; Brown, RH; Brunetti, M; Brylev, L; Byrne, RP; Calvo, A; Canosa, A; Cauchi, RJ; Cereda, C; Chandran, S; Chiò, A; Cichon, S; Cooper-Knock, J; Corcia, P; Corti, S; Couratier, P; Curtis, CJ; D'Alfonso, S; Davey Smith, G; de Carvalho, M; de Klein, N; Deelen, P; Dekker, AM; Demeshonok, V; Dion, PA; Doherty, M; Dolzhenko, E; Drory, V; Durr, A; Eberle, MA; Fan, D; Filosto, M; Fogh, I; Fominykh, V; Franke, A; Franke, L; Freischmidt, A; Furlong, S; Garton, FC; Gaunt, TR; Gaur, N; Gawor, K; Gellera, C; Glass, JD; Glavač, D; Gotkine, M; Graff, C; Grassano, M; Groen, EJN; Gromicho, M; Grosskreutz, J; Hannon, E; Hardiman, O; Hardy, J; Henders, AK; Henderson, RD; Heverin, M; Hofman, A; Hop, PJ; Hübner, CA; Iacoangeli, A; Ilse, B; Jörk, A; Kenna, KP; Kiernan, MC; Kooyman, M; Koritnik, B; Kraft, J; Landers, JE; Lauria, G; Lerner, Y; Lieb, W; Logroscino, G; Lomen-Hoerth, C; Ludolph, AC; Mather, KA; Mathers, S; McCombe, PA; McLaughlin, RL; McRae, AF; Meininger, V; Meyer, T; Mill, J; Millecamps, S; Mitne Neto, M; Moglia, C; Moisse, M; Mora Pardina, JS; Morrison, KE; Needham, M; Nefussy, B; Ngo, ST; Nicholson, GA; Nordin, A; Nöthen, MM; Olsen, CM; Ophoff, RA; Orrell, RW; Osmanovic, A; Padovani, A; Pal, S; Pamphlett, R; Pasterkamp, RJ; Payan, CAM; Petri, S; Pinto, S; Povedano, M; Pupillo, E; Rademakers, R; Ratti, A; Ravnik-Glavač, M; Restuadi, R; Rietschel, M; Ripke, S; Roediger, A; Rogelj, B; Rojas-García, R; Ross, JP; Rouleau, GA; Rowe, DB; Runz, H; Sachdev, PS; Saker-Delye, S; Salachas, F; Sendtner, M; Shatunov, A; Shaw, CE; Shaw, PJ; Shireby, G; Siciliano, G; Silani, V; Singleton, AB; Smith, BN; Sorarù, G; Sproviero, D; Steinbach, R; Stević, Z; Steyn, FJ; Stubendorff, B; Tazelaar, GHP; Theele, E; Ticozzi, N; Tittmann, L; Topp, S; Traynor, BJ; Tsai, E; Uitterlinden, AG; Van Damme, P; van Deerlin, VM; van den Berg, LH; van der Kooi, AJ; van der Spek, RAA; van Eijk, KR; van Es, MA; van Rheenen, W; van Vugt, JJFA; Veldink, JH; Vourc'h, P; Wallace, L; Weber, M; Weishaupt, JH; Westeneng, HJ; Westra, HJ; Whiteman, DC; Wiedau-Pazos, M; Williams, KL; Witte, OW; Wood, NW; Wray, NR; Zabari, M; Zidar, J; Zwamborn, RAJ | 1 |
| Dubey, VK; Ghosh, S; Saha, G; Saudagar, P | 1 |
| Bagautdinova, J; Delavari, F; Eliez, S; Mancini, V; Saleh, MG | 1 |
| Cheng, JY; Deng, YT; Yu, JT | 1 |
| Bornstein, R; Johnson, SC; Morgan, P; Mulholland, MT; Sedensky, M | 1 |
| Butterfield, DA; Hinchie, A; Powell, DK; Ren, X; Swomley, A | 1 |
| Sidoryk-Węgrzynowicz, M; Strużyńska, L | 1 |
| Pandey, UB; Pennuto, M; Polanco, MJ | 1 |
| Chen, Y; Hertz, L | 1 |
| Arslan, F; Barmada, SJ; Kanneganti, V; Liebman, SW; Park, SK; Purushothaman, P; Verma, SC | 1 |
| Cascarina, SM; Machihara, S; Paul, KR; Ross, ED | 1 |
| Chen, Z; Jiang, H; Sequeiros, J; Tang, B | 1 |
| Canneva, F; Dieterich, W; Dobner, J; Schnepf, R; Schulze-Krebs, A; von Hörsten, S | 1 |
| Mishra, R; Mishra, S | 1 |
| Birman, S | 1 |
| De Vivo, G; Gentile, V | 1 |
| André, W; Djian, P; Hoffner, G; Souès, S; Vanhoutteghem, A | 1 |
| Clément, O; Fort, P; Gervasoni, D; Léger, L; Luppi, PH; Peyron, C; Salvert, D; Sapin, E | 1 |
| Collaro, D; De Vivo, G; Gentile, V; Giuliano, A; Martin, A; Sedia, C; Serretiello, E | 1 |
| Nemes, Z | 1 |
| Battaile, K; Cooper, AJ; Jeitner, TM | 1 |
| Chen, J; Herrup, K | 1 |
| Akulov, AE; Koptug, IV; Moshkin, MP; Petrovskiĭ, DV; Petrovskiĭ, ED; Saĭk, OV; Savelov, AA | 1 |
| Hitomi, K | 1 |
| Conrads, TP; Johnson, MD; Kinoshita, Y; McBee, JK; Morrison, RS; Uo, T; Veenstra, TD; Yu, LR | 1 |
| Ben-Zvi, A; Brignull, HR; Gidalevitz, T; Ho, KH; Morimoto, RI | 1 |
| Bates, GP | 1 |
| Harrell, JM; Lieberman, AP; Morishima, Y; Peng, HM; Pratt, WB; Thomas, M | 1 |
| Ahuja, YR; Alluri, RV; Hasan, Q; Rao, P | 1 |
| Jones, BW; Marc, RE; Organisciak, DT; Vaughan, DK; Watt, CB | 1 |
| Gu, Z; Lipton, SA; Nakamura, T | 1 |
| Gendelman, HE; Laurie, C; Mosley, RL; Reynolds, A | 1 |
| Bailey, CK; Fischbeck, KH; Kobayashi, Y; Merry, DE; Taye, AA | 1 |
| Bains, JS; Shaw, CA | 1 |
| Perutz, MF | 1 |
| Orr, HT; Zoghbi, HY | 1 |
| Arai, K; Fujigasaki, H; Fukuda, T; Funata, N; Hattori, T; Takahashi, J; Tanaka, J; Uchihara, T | 1 |
| Perutz, MF; Windle, AH | 1 |
| Akagi, T; Hashikawa, T; Morishima, I; Nukina, N; Tanaka, M | 1 |
| Apostol, BL; Bodai, L; Greenwald, M; Housman, DE; Jackson, GR; Kazantsev, A; Kurokawa, R; Marsh, JL; McCampbell, A; Pallos, J; Poelman, M; Schmidt, E; Steffan, JS; Thompson, LM; Zhu, YZ | 1 |
| Borchelt, DR; Friedlander, RM; Gusella, JF; Gutekunst, CA; Hersch, S; Lebel, LA; MacDonald, ME; Schilling, G; Vonsattel, JP; Vrbanac, V; Wheeler, VC | 1 |
18 review(s) available for glutamine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Topics: Amyotrophic Lateral Sclerosis; Brain; Cholesterol; Disease Progression; Female; Genome-Wide Association Study; Glutamine; Humans; Male; Mendelian Randomization Analysis; Microsatellite Repeats; Mutation; Neurodegenerative Diseases; Neurons; Quantitative Trait Loci; Risk Factors; RNA-Seq | 2021 |
Glutamine metabolism in diseases associated with mitochondrial dysfunction.
Topics: Animals; Glutamine; MELAS Syndrome; Mitochondria; Mitochondrial Diseases; Neurodegenerative Diseases | 2023 |
Astroglial contribution to tau-dependent neurodegeneration.
Topics: Animals; Astrocytes; Glutamic Acid; Glutamine; Humans; Neurodegenerative Diseases; Neurons; tau Proteins | 2019 |
Insulin-like growth factor 1 signaling in motor neuron and polyglutamine diseases: From molecular pathogenesis to therapeutic perspectives.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glutamine; Humans; Insulin-Like Growth Factor I; MAP Kinase Signaling System; Motor Neurons; Muscular Atrophy, Spinal; Neurodegenerative Diseases; Peptides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction | 2020 |
Genetic modifiers of age-at-onset in polyglutamine diseases.
Topics: Age of Onset; Animals; Apoptosis; Gene Regulatory Networks; Glutamine; Humans; Neurodegenerative Diseases; Peptides | 2018 |
Transglutaminase-catalyzed post-translational modifications of proteins in the nervous system and their possible involvement in neurodegenerative diseases.
Topics: Animals; Brain; Brain Chemistry; Genetic Predisposition to Disease; Glutamine; Humans; Inclusion Bodies; Nerve Tissue Proteins; Neurodegenerative Diseases; Protein Processing, Post-Translational; Transglutaminases; Trinucleotide Repeat Expansion | 2008 |
Transglutaminase-catalyzed crosslinking in neurological disease: from experimental evidence to therapeutic inhibition.
Topics: Animals; Brain; Enzyme Inhibitors; Glutamine; Humans; Inclusion Bodies; Neurodegenerative Diseases; Protein Binding; Transglutaminases | 2010 |
The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder.
Topics: Amygdala; Animals; Brain; Brain Mapping; Cataplexy; Emotions; gamma-Aminobutyric Acid; Glutamine; Glycine; Humans; Hypothalamus; Medulla Oblongata; Motor Neurons; Muscle Tonus; Narcolepsy; Nerve Net; Neurodegenerative Diseases; Neurons; Parkinson Disease; Pedunculopontine Tegmental Nucleus; Pons; REM Sleep Behavior Disorder; Sleep, REM; Wakefulness | 2011 |
Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases.
Topics: Animals; Cell Death; Glutamine; Humans; Lysine; Molecular Targeted Therapy; Neurodegenerative Diseases; Peptides; Protein Processing, Post-Translational; Transglutaminases | 2013 |
Effects and analysis of transglutamination on protein aggregation and clearance in neurodegenerative diseases.
Topics: Animals; Chemical Precipitation; Cross-Linking Reagents; Glutamine; Humans; Models, Biological; Molecular Conformation; Neurodegenerative Diseases; Protein Processing, Post-Translational; Proteolysis; Transglutaminases | 2011 |
γ-Glutamylamines and neurodegenerative diseases.
Topics: Amines; Animals; Dipeptides; gamma-Glutamylcyclotransferase; Glutamine; Humans; Lysine; Neurodegenerative Diseases; Protein Processing, Post-Translational; Transglutaminases | 2013 |
[Protein modification by transglutaminase].
Topics: Amines; Animals; Blood Coagulation; Cell Death; Glutamine; Growth Substances; Histones; Humans; Isoenzymes; Neurodegenerative Diseases; Protein Processing, Post-Translational; Proteins; Signal Transduction; Substrate Specificity; Transglutaminases | 2005 |
The proteomics of neurodegeneration.
Topics: Alzheimer Disease; Animals; Down Syndrome; Glutamine; Humans; Motor Neuron Disease; Neurodegenerative Diseases; Parkinson Disease; Proteomics; tau Proteins; Trauma, Nervous System | 2005 |
Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases.
Topics: Aged; Aging; Animals; Brain; Calcium; Glutamine; Humans; Neurodegenerative Diseases; Nitric Oxide; Nitrogen; Protein Conformation; Protein Denaturation; Protein Disulfide-Isomerases; Protein Folding; Signal Transduction | 2007 |
Oxidative stress and the pathogenesis of neurodegenerative disorders.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Free Radicals; Glutamic Acid; Glutamine; Glutathione; Humans; Immunologic Factors; Intercellular Signaling Peptides and Proteins; Macrophage Activation; Microglia; Neurodegenerative Diseases; Oxidative Stress | 2007 |
Glutamine repeats and neurodegenerative diseases: molecular aspects.
Topics: Amino Acid Sequence; Animals; Glutamine; Humans; Huntingtin Protein; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; Peptides; Plant Proteins; Repetitive Sequences, Amino Acid | 1999 |
Glutamine repeats and neurodegeneration.
Topics: Animals; Glutamine; Humans; Huntington Disease; Muscular Disorders, Atrophic; Neurodegenerative Diseases; Peptides; Repetitive Sequences, Amino Acid; Spinocerebellar Ataxias | 2000 |
24 other study(ies) available for glutamine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Gene Alterations Induced by Glutamine (Q) Encoding CAG Repeats Associated with Neurodegeneration.
Topics: Epigenesis, Genetic; Glutamine; Histones; Humans; Neurodegenerative Diseases; Protein Structure, Secondary; Trinucleotide Repeat Expansion; Trinucleotide Repeats | 2023 |
Excitatory/Inhibitory Imbalance Underlies Hippocampal Atrophy in Individuals With 22q11.2 Deletion Syndrome With Psychotic Symptoms.
Topics: Atrophy; DiGeorge Syndrome; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; Neurodegenerative Diseases; Psychotic Disorders | 2023 |
The causal role of circulating amino acids on neurodegenerative disorders: A two-sample Mendelian randomization study.
Topics: Alzheimer Disease; Amino Acids; Causality; Genome-Wide Association Study; Glutamine; Humans; Lewy Body Disease; Mendelian Randomization Analysis; Neurodegenerative Diseases; Parkinson Disease | 2023 |
Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease.
Topics: Animals; Aspartic Acid; Biomarkers; Brain; Corpus Striatum; Disease Models, Animal; Female; Gene Knockout Techniques; Glutamine; Glutathione; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Protein Kinases; Rats; Taurine | 2019 |
Additional mechanisms for brain activation failure due to reduced glucose metabolism-a commentary on Zilberter and Zilberter: The vicious circle of hypometabolism in neurodegenerative diseases.
Topics: Brain; Glucose; Glutamine; Humans; Neurodegenerative Diseases | 2018 |
Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.
Topics: Animals; Asparagine; DNA-Binding Proteins; Glutamine; HEK293 Cells; HSP40 Heat-Shock Proteins; Humans; Neurodegenerative Diseases; Neurons; Peptides; Prions; Protein Aggregates; RNA-Binding Protein FUS; Ubiquitin; Yeasts | 2018 |
Sequence features governing aggregation or degradation of prion-like proteins.
Topics: Amino Acid Sequence; Asparagine; Glutamine; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Neurodegenerative Diseases; Peptide Termination Factors; Prions; Protein Aggregation, Pathological; Protein Domains; Proteolysis; Saccharomyces cerevisiae Proteins | 2018 |
In situ enzymatic activity of transglutaminase isoforms on brain tissue sections of rodents: A new approach to monitor differences in post-translational protein modifications during neurodegeneration.
Topics: Animals; Brain; Glutamine; Humans; Isoenzymes; Male; Mice; Mice, Inbred BALB C; Neurodegenerative Diseases; Peptides; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transglutaminases | 2016 |
Tolerance of hyperammonemia in brain of Heteropneustes fossilis is supported by glutamate-glutamine cycle.
Topics: Animals; Arginase; Brain; Brain Chemistry; Catfishes; Encephalitis; Gene Expression; Glutamic Acid; Glutamine; Hyperammonemia; Myelin Sheath; Neurodegenerative Diseases; Neuroglia; Neurons; RNA | 2017 |
Neurodegeneration: RNA turns number one suspect in polyglutamine diseases.
Topics: Animals; Base Sequence; Drosophila; Drosophila Proteins; Glutamine; Molecular Sequence Data; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Peptides; RNA; Trinucleotide Repeat Expansion | 2008 |
Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Cell Survival; Disease Models, Animal; DNA Damage; Gene Expression; Glutamate-Ammonia Ligase; Glutamine; Hippocampus; Humans; Hydrogen Peroxide; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Stress, Physiological | 2012 |
[Magnetic resonance spectroscopy of metabolic changes in mice brain after 2-deoxy-D-glucose injection].
Topics: Animals; Aspartic Acid; Brain; Choline; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycolysis; Humans; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mice; Neurodegenerative Diseases; Radiography | 2012 |
Progressive disruption of cellular protein folding in models of polyglutamine diseases.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dynamin I; Glutamine; Humans; Mutation; Neurodegenerative Diseases; Peptides; Protein Folding; Temperature; Tropomyosin | 2006 |
BIOMEDICINE: One Misfolded Protein Allows Others to Sneak By.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Glutamine; Humans; Huntington Disease; Mutation; Neurodegenerative Diseases; Peptides; Protein Conformation; Protein Folding; Temperature | 2006 |
Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction.
Topics: Animals; DNA-Binding Proteins; Glutamine; Heat Shock Transcription Factors; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Transgenic; Models, Biological; Neurodegenerative Diseases; NIH 3T3 Cells; Peptides; Protein Transport; Receptors, Androgen; Transcription Factors | 2006 |
Role of glutamine deamidation in neurodegenerative diseases associated with triplet repeat expansions: a hypothesis.
Topics: Amides; Diagnosis, Differential; Glutamine; Humans; Neurodegenerative Diseases; Neurons; Signal Transduction; Trinucleotide Repeat Expansion | 2006 |
Neural plasticity revealed by light-induced photoreceptor lesions.
Topics: Animals; Circadian Rhythm; Glutamine; Humans; Light; Microscopy, Electron; Neurodegenerative Diseases; Neurons; Photoreceptor Cells, Vertebrate; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Time Factors | 2006 |
Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy.
Topics: Animals; Blotting, Western; Cell Line; Cell Nucleus; COS Cells; Cytoplasm; Genetic Linkage; Glutamine; Muscular Atrophy, Spinal; Neurodegenerative Diseases; Protein Processing, Post-Translational; Receptor Aggregation; Receptors, Androgen; Recombinant Fusion Proteins; Repetitive Sequences, Nucleic Acid; Transfection; X Chromosome | 1998 |
Did consumption of flour bleached by the agene process contribute to the incidence of neurological disease?
Topics: Buthionine Sulfoximine; Chlorides; Flour; Food Contamination; Food Handling; Glutamine; Glutathione; Humans; Methionine Sulfoximine; Models, Neurological; Nervous System; Neurodegenerative Diseases; Nitrogen Compounds; Oxidative Stress | 1998 |
Recruitment of nonexpanded polyglutamine proteins to intranuclear aggregates in neuronal intranuclear hyaline inclusion disease.
Topics: Adult; Ataxin-3; Ataxins; Cell Nucleus; Disease Progression; DNA-Binding Proteins; Fatal Outcome; Female; Glutamine; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Macromolecular Substances; Male; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Proteins; Repressor Proteins; TATA-Box Binding Protein; Transcription Factors; Trinucleotide Repeats; Ubiquitins | 2001 |
Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats.
Topics: Age of Onset; Animals; Cell Death; Cell Nucleus; Glutamine; Humans; Huntington Disease; Neurodegenerative Diseases; Neurons; Repetitive Sequences, Amino Acid | 2001 |
Intra- and intermolecular beta-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Circular Dichroism; Congo Red; Dose-Response Relationship, Drug; Escherichia coli; Glutamine; Immunoblotting; Magnetic Resonance Spectroscopy; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutation; Myoglobin; Neurodegenerative Diseases; Peptides; Plasmids; Protein Conformation; Protein Folding; Protein Structure, Secondary; Sequence Homology, Amino Acid; Spectrophotometry, Infrared; Time Factors; Trinucleotide Repeat Expansion; Ultraviolet Rays; Whales | 2001 |
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
Topics: Acetylation; Acetyltransferases; Animals; Animals, Genetically Modified; CREB-Binding Protein; Disease Models, Animal; Drosophila; Drosophila Proteins; E1A-Associated p300 Protein; Enzyme Inhibitors; Gene Expression Regulation; Glutamine; Glutathione Transferase; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Huntingtin Protein; Huntington Disease; Nerve Degeneration; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; PC12 Cells; Peptides; Protein Structure, Tertiary; Rats; Repetitive Sequences, Amino Acid; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sin3 Histone Deacetylase and Corepressor Complex; Trans-Activators | 2001 |
Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice.
Topics: Animals; Caspase 1; Cell Nucleus; Corpus Striatum; Gait; Genes, Dominant; Glutamine; Huntingtin Protein; Huntington Disease; Immunologic Factors; Mice; Mice, Knockout; Mice, Transgenic; Mutagenesis, Insertional; Nerve Tissue Proteins; Neurodegenerative Diseases; Nuclear Proteins; Phenotype; Time Factors; Trinucleotide Repeats | 2002 |