glutamine and Colorectal Cancer

glutamine has been researched along with Colorectal Cancer in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.45)18.7374
1990's3 (4.35)18.2507
2000's12 (17.39)29.6817
2010's31 (44.93)24.3611
2020's22 (31.88)2.80

Authors

AuthorsStudies
Hua, Q; Lin, Z; Ren, J; Wang, H; Wang, L; Xu, G; Yu, D; Zhang, B; Zhang, D; Zhang, T; Zhao, L1
Liu, J; Song, M1
Cong, X; Liu, C; Sun, H; Wang, X; Zhang, C; Zheng, Y1
Inoue, H; Kageyama, S; Kawauchi, A; Kim, CJ; Minami, K; Shirasawa, S; Tambe, Y; Tanaka, H; Terado, T; Tsunoda, T; Ushio, A1
Kong, P; Liu, F; Tang, S; Wang, Q; Wu, R1
Chen, B; Fu, W; Gaiddon, C; Gross, I; Han, X; Hou, L; Hou, Y; Li, L; Liang, Y; Long, B; Meng, X; Pang, W; Wang, L; Wang, Y; Xu, C; Yao, H; Zhang, X; Zhong, T; Zhou, K1
Chen, JK; Huang, CY; Kuo, WT1
Baiocco, G; Guardamagna, I; Iaria, O; Ivaldi, GB; Liotta, M; Lonati, L; Maggi, M; Mentana, A; Pessino, G; Previtali, A; Scotti, C; Tabarelli de Fatis, P; Uggè, V1
Achaintre, D; Adamski, J; Amiano, P; Ardanaz, E; Bešević, J; Boutron-Ruault, MC; Breeur, M; Bueno-de-Mesquita, B; Chadeau-Hyam, M; Colorado-Yohar, S; Cross, AJ; Dahm, CC; Derksen, JWG; Dimou, N; Eichelmann, F; Eriksen, AK; Ferrari, P; Gicquiau, A; Gunter, MJ; Huybrechts, I; Jenab, M; Kaaks, R; Katzke, V; Keun, H; Murphy, N; Nøst, TH; Overvad, K; Palli, D; Pasanisi, F; Prehn, C; Rinaldi, S; Rothwell, JA; Sánchez, MJ; Sandanger, TM; Scalbert, A; Schulze, MB; Severi, G; Skeie, G; Smith-Byrne, K; Tjønneland, A; Travis, R; Tsilidis, KK; Tumino, R; van Guelpen, B; Viallon, V; Vidman, L; Vineis, P; Wedekind, R; Zamora-Ros, R1
Bae, SW; Cohen, AS; Geng, L; Georgiou, DK; Manning, HC; Tantawy, MN; Wang, J; Wen, X1
Chen, B; Li, Y; Lu, W; Luan, T; Sun, J; Tu, L; Zhang, R1
Chang, C; Chen, X; Hu, Y; Li, K; Ye, J1
Bao, T; Chen, J; Li, G; Li, P; Xiong, K; Yang, X; Zhang, Y1
Dai, W; Han, D; Mo, W; Xu, W; Xu, X1
Chen, H; Ding, YQ; Gao, JW; Han, Y; Hu, SS; Tan, TY; Wang, L; Wang, S; Wang, YQ; Yang, MH; Zhao, L1
Hara, Y; Hayashi, N; Masuko, K; Masuko, T; Minami, Y; Ueda, S; Yamasaki, A; Yoshimoto, S1
Brunengraber, H; Chen, V; Conlon, RA; Croniger, C; Fearon, E; Feng, Y; Hao, Y; Markowitz, S; Puchowicz, M; Wang, L; Wang, Z; Zhao, X; Zhao, Y1
Kang, MJ; Kim, MJ; Lee, SG; Noh, JY; Park, JM; Pyun, JC; Yoo, BC; Yun, TG1
Chou, YJ; Kober, KM; Kuo, CH; Kuo, TC; Liang, JT; Miaskowski, C; Shun, SC; Tseng, YJ; Yeh, KH1
Bian, X; Chan, LS; Chen, H; Gou, H; Ji, F; Kang, W; Li, W; Liu, D; Qian, Y; Shirasawa, S; Sung, JJ; Wong, CC; Wu, JL; Xu, J; Yat Luk, ST; Yu, J; Zhou, Q1
Edwards, RA; Habowski, AN; Hanse, EA; Ishak Gabra, MB; Kong, M; Li, H; Liao, SY; Lowman, XH; Ooi, AM; Tran, TQ; Waterman, ML; Yang, Y1
Barry, ST; Brown, G; Bunch, J; Bushell, M; Campbell, AD; Ceteci, F; Clark, W; Critchlow, SE; Dexter, A; Dunne, PD; Fey, SK; Gay, DM; Gilroy, K; Goodwin, RJA; Gottlieb, E; Hall, H; Hamm, G; Hedley, A; Jackstadt, R; Johnson, ER; Knight, JRP; Leach, JDG; Lewis, DY; Mackay, GM; Malla, SB; Malviya, G; Mrowinska, A; Murta, T; Najumudeen, AK; Nikula, CJ; Nixon, C; Race, AM; Ridgway, RA; Rodriguez-Blanco, G; Sansom, OJ; Solovyev, D; Steven, RT; Strathdee, D; Sumpton, D; Takats, Z; Tardito, S; Vlahov, N1
Cai, C; Tang, C; Xin, H; Zeng, B; Zeng, J1
Cheon, JH; Hong, SP; Il Kim, T; Kang, JY; Kim, JH; Kim, WH; Kwon, JH; Lee, HJ; Lee, KJ; Park, SJ; Seo, Y; Yoon, JP1
Chin, KF; Golkhalkhali, B; Paliany, AS; Rajandram, R1
Chen, YX; Fang, JY; Fu, LN; Gao, QY; Sun, DF; Tan, J; Wang, HL; Wang, JL; Wang, YQ; Xu, J; Zou, TH1
Hu, M; Liu, L; Yao, W1
Baumann, J; Baumann, M; Brockmeier, U; Classen, F; Göpelt, K; Kranz, P; Metzen, E; Pompsch, M; Riffkin, H; Wolf, A1
Lai, M; Li, J; Qi, LW; Wang, H; Zhu, Y1
Chang, PH; Chou, WC; Fan, CW; Huang, JS; Ling, HH; Pan, YP; Tseng, WK; Wang, CH; Wu, TH; Yeh, KY1
Wang, G; Wang, JJ; Wang, YZ; Xu, K; Yin, PH; Yu, Y1
Ji, G; Li, N; Tian, Y; Wang, K; Wang, Z1
Cai, G; Cai, S; Chen, T; Cheng, Y; Dong, T; Feng, B; Hu, X; Jia, W; Qiu, Y; Tan, B; Xie, G; Xu, LX; Zhang, M; Zhang, Y; Zhao, A; Zhao, L; Zheng, M; Zhou, Z; Zou, X1
Chihara, Y; Eto, S; Kato, Y; Kobayashi, T; Kuniyasu, H; Luo, Y; Miyano, H; Ohmori, H; Sasahira, T; Sasaki, T; Shimbo, K; Yoneda, J1
Li, Z; Wang, Y; Wu, H; Yang, P; Zhang, L1
Akagi, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H; Uchida, S; Ushijima, M1
Cai, C; Chen, R; Fu, Z; Gong, Y; Han, F; Li, Y; Li, Z; Lin, Q; Liu, G; Tang, C; Yang, B; Ye, H; Ye, L; Yu, M; Zeng, B; Zhao, X; Zhou, Q; Zhou, Y; Zhu, J1
Colvin, H; Doki, Y; Hamabe, A; Hata, T; Ishii, H; Kawamoto, K; Konno, M; Koseki, J; Miyo, M; Mizushima, T; Mori, M; Nishida, N; Nishimura, J; Ogawa, H; Takemasa, I; Uemura, M; Yamamoto, H1
Chu, D; Guo, Y; Li, J; Li, X; Liu, X; Shen, L; Sun, X; Wei, L; Xu, X; Yang, G; Yao, L; Zhang, J1
Bhalla, K; Boros, LG; Boxer, MB; DeBerardinis, RJ; Dewi, R; Drapkin, R; Duraisamy, S; Girnun, GD; Gordon, C; Hwang, BJ; Liu, WJ; Montal, ED; Ou, L; Powers, RS; Rohde, JM; Ropell, AE; Shroyer, KR; Sudderth, J; Twaddel, W; Wong, KK1
Chang, PH; Chen, CH; Chou, WC; Fan, CW; Huang, JS; Pan, YP; Tseng, WK; Wang, CH; Yeh, KY1
Chen, XP; Huang, JP; Jiang, XW; Wang, QZ1
Chiang, BH; Chiu, HM; Huang, YT; Lin, YW1
Chen, X; Cheng, J; Huang, G; Liu, C; Liu, X; Peng, Z; Yu, F; Yuan, C1
Fan, Y; Ji, G; Li, J; Sun, L; Tian, Y; Wang, J; Wang, K; Wang, L; Wang, Y; Wang, Z; Ye, Y1
Brunengraber, H; Cao, B; Conlon, RA; Dong, B; Feng, X; Fink, S; Guan, BJ; Hao, Y; Hatzoglou, M; Jin, Z; Kinzler, KW; Krokowski, D; LaFramboise, T; Li, Q; Markowitz, S; Meropol, NJ; Samuels, Y; Velculescu, VE; Vogelstein, B; Wang, C; Wang, Z; Willis, JE; Xiang, M; Xu, C; Xu, Y; Zhang, GF1
Hasegawa, S; Inamoto, S; Iwamoto, M; Kawada, K; Sakai, Y; Sasazuki, T; Shirasawa, S; Toda, K1
Asai, A; Colvin, H; Doki, Y; Haraguchi, N; Hata, T; Ishii, H; Kawamoto, K; Konno, M; Koseki, J; Mizushima, T; Mori, M; Nishida, N; Nishimura, J; Satoh, T; Takahashi, H; Tsunekuni, K1
Ci, Y; Hu, Y; Huang, F; Hui, K; Shi, L; Xu, C; Yang, Y; Zhang, Q; Zhao, J; Zhou, R1
Busch, EL; Fargo, DC; Huang, W; Ji, M; Jin, A; Keku, TO; Lewis, D; Li, L; Li, X; Ren, NSX; Sandler, RS; Tokar, EJ; Wu, WKK; Xu, X; Zhang, Y1
Inoue, N; Kasahara, M; Miyaishi, A; Osawa, K; Osawa, Y; Shimada, E; Tabuchi, Y; Takahashi, J; Tanaka, K; Tsutou, A; Yamamoto, M; Yoshida, K1
Li, J; Li, Y; Liu, F; Ni, X; Ping, X; Yu, B1
Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y1
Engin, A; Engin, AB; Karahalil, B; Karakaya, AE1
Aghasadeghi, MR; Amanlou, M; Ardestani, MS; Ebrahimi, SE; Mehravi, B; Nourmohammadi, Z; Omoomi, FD; Pourhosseini, S; Rahimi, P; Siadat, SD; Tabasi, MA1
Matono, K; Ogata, Y; Shirouzu, K1
Ansari, R; Cheng, L; Helft, P; Juliar, B; Loehrer, P; Pan, CX; Pletcher, W; Seitz, D; Sweeney, C; Vinson, J1
Cai, JL; Chen, R; Jiang, AF; Zhou, B1
Antonione, R; Barazzoni, R; Biolo, G; Ciocchi, B; Dal Mas, V; De Cicco, M; Dore, F; Guarnieri, G; Lorenzon, S; Zanetti, M1
Boelens, PG; Dejong, CH; Deutz, NE; Melis, GC; Siroen, MP; Soeters, PB; van de Poll, MC; van Leeuwen, PA1
Chen, PM; Chen, WS; Chiou, TJ; Jiang, JK; Lin, JK; Lin, TC; Liu, JH; Wang, HS; Wang, WS; Yen, CC1
Benais-Pont, G; Buchegger, F; Dupertuis, YM; Pichard, C1
O'Dwyer, ST1
Halliday, MI; Hamilton, PW; Rowlands, BJ; Williamson, KE1
Powell-Tuck, J1
Buhl, K; Decker-Baumann, C; Dueck, M; Frohmüller, S; Schlag, PM; von Herbay, A1
Bode, BP; Pawlik, TM; Souba, WW; Sweeney, TJ1
Abdel-Rahman, SZ; Bondy, ML; El-Badawy, SA; Khaled, HM; Levin, B; Omar, S; Seifeldin, IA; Soliman, AS1
Crone, C; Eggstein, S; Farthmann, EH; Imdahl, A1

Reviews

3 review(s) available for glutamine and Colorectal Cancer

ArticleYear
Comparative Effects of Different Nutritional Supplements on Inflammation, Nutritional Status, and Clinical Outcomes in Colorectal Cancer Patients: A Systematic Review and Network Meta-Analysis.
    Nutrients, 2023, Jun-16, Volume: 15, Issue:12

    Topics: Arginine; Colorectal Neoplasms; Dietary Supplements; Fatty Acids, Omega-3; Glutamine; Humans; Inflammation; Network Meta-Analysis; Nutritional Status

2023
Effects of glutamine on plasma protein and inflammation in postoperative patients with colorectal cancer: a meta-analysis of randomized controlled trials.
    International journal of colorectal disease, 2023, Aug-11, Volume: 38, Issue:1

    Topics: Albumins; Colorectal Neoplasms; Glutamine; Humans; Inflammation; Randomized Controlled Trials as Topic; Tumor Necrosis Factor-alpha

2023
The Roles of Adjuvant Supplements in Colorectal Cancer Patients on Chemotherapy - Reaping Benefits from Metabolic Crosstalk.
    Nutrition and cancer, 2018, 01-11, Volume: 70, Issue:2

    Topics: Antineoplastic Agents; Colorectal Neoplasms; Dietary Supplements; Fatty Acids, Omega-3; Glutamine; Humans; Probiotics

2018

Trials

9 trial(s) available for glutamine and Colorectal Cancer

ArticleYear
Randomized phase II study of 5-fluorouracil hepatic arterial infusion with or without antineoplastons as an adjuvant therapy after hepatectomy for liver metastases from colorectal cancer.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Glutamine; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2015
[Effects of Couplet Medicines (Astragalus Membranaceus and Jiaozhen) on Intestinal Barrier in Postoperative Colorectal Cancer Patients].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2015, Volume: 35, Issue:11

    Topics: Amine Oxidase (Copper-Containing); Antineoplastic Combined Chemotherapy Protocols; Astragalus propinquus; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drugs, Chinese Herbal; Glutamine; Humans; Intestinal Mucosa; Intestines; Lactic Acid; Tumor Necrosis Factor-alpha

2015
Clinical trial: prophylactic intravenous alanyl-glutamine reduces the severity of gastrointestinal toxicity induced by chemotherapy--a randomized crossover study.
    Alimentary pharmacology & therapeutics, 2009, Sep-01, Volume: 30, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dipeptides; Double-Blind Method; Female; Glutamine; Humans; Infusions, Intravenous; Male; Middle Aged; Stomach Neoplasms

2009
A phase II trial of irinotecan, 5-fluorouracil and leucovorin combined with celecoxib and glutamine as first-line therapy for advanced colorectal cancer.
    Oncology, 2005, Volume: 69, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Celecoxib; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Glutamine; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Pyrazoles; Sulfonamides; Treatment Outcome

2005
[Effect of immune-enhanced enteral diet on postoperative immunological function in patients with colorectal cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2005, Volume: 8, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Colorectal Neoplasms; Enteral Nutrition; Fatty Acids, Omega-3; Female; Glutamine; Humans; Male; Middle Aged; Postoperative Period

2005
Response of muscle protein and glutamine kinetics to branched-chain-enriched amino acids in intensive care patients after radical cancer surgery.
    Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:5

    Topics: Amino Acids, Branched-Chain; Blood Glucose; Colorectal Neoplasms; Colorectal Surgery; Critical Care; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Glutamine; Humans; Infusions, Intravenous; Insulin; Leg; Leucine; Male; Middle Aged; Muscle Proteins; Plethysmography; Uterine Cervical Neoplasms

2006
Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients.
    The oncologist, 2007, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Colorectal Neoplasms; Female; Fluorouracil; Glutamine; Humans; Leucovorin; Male; Middle Aged; Nervous System Diseases; Neuroprotective Agents; Organoplatinum Compounds; Oxaliplatin; Pilot Projects; Treatment Outcome

2007
Total parenteral nutrition with glutamine dipeptide shortened hospital stays and improved immune status and nitrogen economy after major abdominal surgery.
    Gut, 1999, Volume: 44, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Female; Glutamine; Humans; Male; Middle Aged; Parenteral Nutrition, Total; Postoperative Care; Randomized Controlled Trials as Topic; Treatment Outcome

1999
Reduction of chemotherapy-induced side-effects by parenteral glutamine supplementation in patients with metastatic colorectal cancer.
    European journal of cancer (Oxford, England : 1990), 1999, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Glutamine; Humans; Infusions, Parenteral; Intestinal Mucosa; Leucovorin; Male; Middle Aged; Prospective Studies

1999

Other Studies

57 other study(ies) available for glutamine and Colorectal Cancer

ArticleYear
CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin.
    Oncogene, 2021, Volume: 40, Issue:46

    Topics: Amino Acid Transport System A; Amino Acid Transport System ASC; Animals; beta Catenin; Cell Line, Tumor; Cell Nucleus; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glutamine; HCT116 Cells; Humans; Hyaluronoglucosaminidase; Mice; Minor Histocompatibility Antigens; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Neoplasm Transplantation; Transcription, Genetic

2021
Circ_0067717 promotes colorectal cancer cell growth, invasion and glutamine metabolism by serving as a miR-497-5p sponge to upregulate SLC7A5.
    Histology and histopathology, 2023, Volume: 38, Issue:1

    Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Glutamine; Humans; Large Neutral Amino Acid-Transporter 1; MicroRNAs

2023
Glutamine deficiency promotes recurrence and metastasis in colorectal cancer through enhancing epithelial-mesenchymal transition.
    Journal of translational medicine, 2022, 07-22, Volume: 20, Issue:1

    Topics: Carcinoembryonic Antigen; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Glutamine; Humans; Prognosis

2022
Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells.
    International journal of oncology, 2022, Volume: 61, Issue:3

    Topics: Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Glutamine; Humans; Lipids; Lipogenesis; Pancreatic Neoplasms; Phenanthrenes; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; Signal Transduction

2022
Hsa_circ_0003602 Contributes to the Progression of Colorectal Cancer by Mediating the miR-149-5p/SLC38A1 Axis.
    Gut and liver, 2023, 03-15, Volume: 17, Issue:2

    Topics: Amino Acid Transport System A; Animals; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Glutamine; Humans; MicroRNAs

2023
Anti-tumor effects of P-LPK-CPT, a peptide-camptothecin conjugate, in colorectal cancer.
    Communications biology, 2022, 11-14, Volume: 5, Issue:1

    Topics: Amino Acid Transport System ASC; Camptothecin; Colorectal Neoplasms; Glutamine; Humans; Minor Histocompatibility Antigens; Molecular Docking Simulation; Peptides

2022
Glutamine induces remodeling of tight junctions in Caco-2 colorectal cancer cell.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Caco-2 Cells; Colorectal Neoplasms; Glucose; Glutamine; Humans; Tight Junctions

2022
Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53
    International journal of molecular sciences, 2023, Feb-03, Volume: 24, Issue:3

    Topics: Asparaginase; Asparagine; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Glutamine; Humans; Radiation, Ionizing; Tumor Suppressor Protein p53

2023
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts.
    BMC medicine, 2023, 02-28, Volume: 21, Issue:1

    Topics: Amino Acids; Biological Specimen Banks; Colorectal Neoplasms; Glutamine; Histidine; Humans; Prospective Studies; United Kingdom

2023
Feasibility of [
    Tomography (Ann Arbor, Mich.), 2023, 02-24, Volume: 9, Issue:2

    Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; ErbB Receptors; Feasibility Studies; Glutamates; Glutaminase; Glutamine; Humans; Mice; Positron-Emission Tomography; Proto-Oncogene Proteins p21(ras)

2023
Constructing interactive networks of functional genes and metabolites to uncover the cellular events related to colorectal cancer cell migration induced by arsenite.
    Environment international, 2023, Volume: 174

    Topics: Arsenites; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Glutamine; Humans

2023
Systematic analysis of glutamine metabolism family genes and exploration of the biological role of GPT in colorectal cancer.
    Aging, 2023, 10-17, Volume: 15, Issue:21

    Topics: Colorectal Neoplasms; Databases, Factual; Epithelial Cells; Glutamine; Humans; Oncogenes; Prognosis; Tumor Microenvironment

2023
SLC25A21 downregulation promotes KRAS-mutant colorectal cancer progression by increasing glutamine anaplerosis.
    JCI insight, 2023, Nov-08, Volume: 8, Issue:21

    Topics: Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Glutamine; Guanosine Triphosphate; Humans; Proto-Oncogene Proteins p21(ras)

2023
Anti-tumor effects of an antagonistic mAb against the ASCT2 amino acid transporter on KRAS-mutated human colorectal cancer cells.
    Cancer medicine, 2020, Volume: 9, Issue:1

    Topics: Amino Acid Transport System ASC; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Female; Gene Knockout Techniques; Glutamine; HEK293 Cells; Humans; Mice; Minor Histocompatibility Antigens; Molecular Targeted Therapy; Mutation; Proto-Oncogene Proteins p21(ras); Xenograft Model Antitumor Assays

2020
Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo.
    Scientific reports, 2019, 12-16, Volume: 9, Issue:1

    Topics: Animals; Carbon Isotopes; Citric Acid Cycle; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Female; Glutamine; HCT116 Cells; Humans; Kinetics; Mice, Nude; Mutation; Subcutaneous Tissue; Substrate Specificity; Xenograft Model Antitumor Assays

2019
Simultaneous Analysis of Multiple Cancer Biomarkers Using MALDI-TOF Mass Spectrometry Based on a Parylene-Matrix Chip.
    Journal of the American Society for Mass Spectrometry, 2020, Apr-01, Volume: 31, Issue:4

    Topics: Bile Duct Neoplasms; Biomarkers, Tumor; Cholangiocarcinoma; Colorectal Neoplasms; Equipment Design; Glutamine; Humans; Limit of Detection; Lysophosphatidylcholines; Polymers; Pyridones; Reproducibility of Results; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xylenes

2020
A Pilot Study of Metabolomic Pathways Associated With Fatigue in Survivors of Colorectal Cancer.
    Biological research for nursing, 2021, Volume: 23, Issue:1

    Topics: Aged; Cancer Survivors; Colorectal Neoplasms; Fatigue; Female; Glutamic Acid; Glutamine; Glutathione; Humans; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Pilot Projects; Surveys and Questionnaires; Taiwan

2021
In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance.
    Gastroenterology, 2020, Volume: 159, Issue:6

    Topics: Animals; Colon; Colorectal Neoplasms; DNA Demethylation; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutamine; Hong Kong; Humans; Intestinal Mucosa; Kaplan-Meier Estimate; Ketoglutaric Acids; Male; Mice, Knockout; Mitochondrial Membrane Transport Proteins; Neoplastic Stem Cells; Proto-Oncogene Proteins p21(ras); Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2020
α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer.
    Nature cancer, 2020, Volume: 1, Issue:3

    Topics: Colorectal Neoplasms; Glutamine; Humans; Ketoglutaric Acids; Organoids; Tumor Microenvironment; Wnt Signaling Pathway

2020
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
    Nature genetics, 2021, Volume: 53, Issue:1

    Topics: 5' Untranslated Regions; Amino Acid Transport System ASC; Animals; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Intestinal Mucosa; Kaplan-Meier Estimate; Large Neutral Amino Acid-Transporter 1; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Mutation; Neoplasm Metastasis; Oncogenes; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases

2021
[Effect of ASCT2 gene knock-down by shRNA on biological behaviors of colorectal cancer cells].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2017, Apr-25, Volume: 20, Issue:4

    Topics: Amino Acid Transport System ASC; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Gene Knockdown Techniques; Glutamine; Humans; Minor Histocompatibility Antigens; Neoplasm Invasiveness; Oncogenes; RNA, Messenger; RNA, Small Interfering; Transfection

2017
Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism.
    Scientific reports, 2018, 01-11, Volume: 8, Issue:1

    Topics: Adenylate Kinase; Animals; Benzophenanthridines; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; HT29 Cells; Humans; Metformin; Mice; Neoplasm Transplantation; Neoplastic Stem Cells; Oxygen Consumption; Ribosomal Protein S6 Kinases

2018
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
    Nature communications, 2018, 02-07, Volume: 9, Issue:1

    Topics: Carcinogenesis; Cell Proliferation; Citric Acid Cycle; Colorectal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutamate Dehydrogenase; Glutamine; HCT116 Cells; Humans; RNA Interference; Sirtuins

2018
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
    Gene, 2018, Dec-15, Volume: 678

    Topics: Antineoplastic Agents, Phytogenic; Cell Nucleus; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; HCT116 Cells; Humans; Phosphorylation; Protein Transport; Sesquiterpenes; Time Factors; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2018
Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells.
    Experimental cell research, 2019, 01-01, Volume: 374, Issue:1

    Topics: Apoptosis; Autophagy; Autophagy-Related Protein 7; Beclin-1; Cell Hypoxia; Cell Line, Tumor; Colorectal Neoplasms; Glutamine; Humans; Oxygen; Radiation, Ionizing

2019
Tyrosine and Glutamine-Leucine Are Metabolic Markers of Early-Stage Colorectal Cancers.
    Gastroenterology, 2019, Volume: 157, Issue:1

    Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Dipeptides; Female; Glutamine; Humans; Leucine; Male; Metabolic Syndrome; Metabolomics; Middle Aged; Neoplasm Staging; Principal Component Analysis; Spectrometry, Mass, Electrospray Ionization; Tyrosine

2019
Clinical Significance of Serum Glutamine Level in Patients with Colorectal Cancer.
    Nutrients, 2019, Apr-21, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Biomarkers, Tumor; C-Reactive Protein; Carcinoembryonic Antigen; Colorectal Neoplasms; Cytokines; Disease Progression; Female; Glutamine; Humans; Inflammation; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Analysis; Young Adult

2019
Triterpenoids Extracted from
    Nutrition and cancer, 2020, Volume: 72, Issue:2

    Topics: Animals; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Colorectal Neoplasms; Flavonoids; Gene Regulatory Networks; Glutamine; Glycolysis; Humans; Male; Metabolome; Mice; Mice, Inbred BALB C; Mice, Nude; Pentacyclic Triterpenes; Plant Extracts; Rhus; Tandem Mass Spectrometry; Triterpenes; Validation Studies as Topic; Xenograft Model Antitumor Assays

2020
Chemopreventive effect of dietary glutamine on colitis-associated colon tumorigenesis in mice.
    Carcinogenesis, 2013, Volume: 34, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Biomarkers, Tumor; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colitis; Colon; Colorectal Neoplasms; Cyclooxygenase 2; Dextran Sulfate; Dietary Supplements; Enzyme-Linked Immunosorbent Assay; Female; Glutamine; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Real-Time Polymerase Chain Reaction; Rectum; Severity of Illness Index

2013
Metabonomics identifies serum metabolite markers of colorectal cancer.
    Journal of proteome research, 2013, Jun-07, Volume: 12, Issue:6

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoembryonic Antigen; Case-Control Studies; Citric Acid Cycle; Colorectal Neoplasms; Discriminant Analysis; Fatty Acids; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Least-Squares Analysis; Male; Metabolomics; Microbiota; Middle Aged; Neoplasm Staging; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics, Nonparametric; Urea

2013
Cancer usurps skeletal muscle as an energy repository.
    Cancer research, 2014, Jan-01, Volume: 74, Issue:1

    Topics: Amino Acids; Animals; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Energy Metabolism; Glutamine; Heterografts; HMGB1 Protein; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mitochondria, Muscle; Muscle, Skeletal; Recombinant Proteins

2014
GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the β-catenin signaling.
    Oncotarget, 2014, Jul-30, Volume: 5, Issue:14

    Topics: Animals; beta Catenin; Cadherins; Cell Survival; Colorectal Neoplasms; Dogs; Down-Regulation; Endoplasmic Reticulum Chaperone BiP; Glucose; Glutamine; Heat-Shock Proteins; HT29 Cells; Humans; Madin Darby Canine Kidney Cells; Proto-Oncogene Proteins c-myc; Signal Transduction; Transfection

2014
Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients.
    Journal of translational medicine, 2015, May-07, Volume: 13

    Topics: Aged; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Glutamate Dehydrogenase; Glutamine; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Proportional Hazards Models; Up-Regulation

2015
Tumour-suppressive function of SIRT4 in human colorectal cancer.
    British journal of cancer, 2015, Jul-28, Volume: 113, Issue:3

    Topics: Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Genes, Tumor Suppressor; Glutamine; HCT116 Cells; HT29 Cells; Humans; Mitochondrial Proteins; Neoplasm Invasiveness; Prognosis; Sirtuins; Tumor Cells, Cultured

2015
Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression.
    Oncotarget, 2015, Sep-22, Volume: 6, Issue:28

    Topics: Amino Acid Transport System ASC; Animals; beta Catenin; Caco-2 Cells; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucose; Glutaminase; Glutamine; Glycolysis; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Lactic Acid; Male; Mice, Nude; Middle Aged; Minor Histocompatibility Antigens; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; Time Factors; Transcription, Genetic; Transfection; Tumor Burden; Tumor Suppressor Proteins

2015
PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth.
    Molecular cell, 2015, Nov-19, Volume: 60, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Glucose; Glutamine; Glycolysis; HT29 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Neoplasm Transplantation; Phosphoenolpyruvate Carboxykinase (ATP); TOR Serine-Threonine Kinases

2015
Relationship between pre-treatment nutritional status, serum glutamine, arginine levels and clinicopathological features in Taiwan colorectal cancer patients.
    Asia Pacific journal of clinical nutrition, 2015, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Arginine; Body Mass Index; C-Reactive Protein; Colorectal Neoplasms; Disease-Free Survival; Female; Glutamine; Humans; Hypoalbuminemia; Length of Stay; Male; Malnutrition; Middle Aged; Neoplasm Staging; Nutrition Assessment; Nutritional Status; Taiwan; Weight Loss

2015
Curcumin Induces Apoptosis of Colorectal Cancer Stem Cells by Coupling with CD44 Marker.
    Journal of agricultural and food chemistry, 2016, Mar-23, Volume: 64, Issue:11

    Topics: Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Curcumin; Glutamine; Humans; Hyaluronan Receptors; Metabolome; Neoplastic Stem Cells

2016
Clinical and therapeutic significance of sirtuin-4 expression in colorectal cancer.
    Oncology reports, 2016, Volume: 35, Issue:5

    Topics: Aged; Animals; Antimetabolites, Antineoplastic; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Gene Expression; Glutamine; HT29 Cells; Humans; Inhibitory Concentration 50; Kaplan-Meier Estimate; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mitochondrial Proteins; Multivariate Analysis; Neoplasm Transplantation; Prognosis; Proportional Hazards Models; Sirtuins

2016
Chemopreventive Effect of Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with Modulation of the DEPTOR/mTOR Signaling Pathway.
    Nutrients, 2016, May-02, Volume: 8, Issue:5

    Topics: Animals; Colitis; Colorectal Neoplasms; Diet; Gene Expression Regulation; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Mice; Signal Transduction; TOR Serine-Threonine Kinases

2016
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
    Nature communications, 2016, 06-20, Volume: 7

    Topics: Activating Transcription Factor 4; Adenocarcinoma; Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Citric Acid Cycle; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glutamine; HCT116 Cells; HT29 Cells; Humans; Ketoglutaric Acids; Mice; Mice, Nude; Mutation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction; Transaminases; Tumor Burden; Xenograft Model Antitumor Assays

2016
Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
    Neoplasia (New York, N.Y.), 2016, Volume: 18, Issue:11

    Topics: Adaptation, Biological; Amino Acids; Animals; Aspartate-Ammonia Ligase; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Female; Glutamine; Heterografts; Humans; Mice; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Burden

2016
Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer.
    Scientific reports, 2016, 11-08, Volume: 6

    Topics: Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Glutamine; Glutarates; HCT116 Cells; HEK293 Cells; Histones; HT29 Cells; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasm Metastasis; Promoter Regions, Genetic; Zinc Finger E-box-Binding Homeobox 1

2016
Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells.
    Oncotarget, 2017, Mar-21, Volume: 8, Issue:12

    Topics: Adenomatous Polyposis Coli Protein; Antigens, CD; Antineoplastic Agents; Apoptosis; Blotting, Western; Cadherins; Cell Line, Tumor; Colorectal Neoplasms; Fluorescent Antibody Technique; Gene Knockdown Techniques; Glutaminase; Glutamine; Humans; Immunohistochemistry; Immunoprecipitation; Real-Time Polymerase Chain Reaction; Selenious Acid; Signal Transduction

2017
Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development.
    Current biology : CB, 2017, Feb-20, Volume: 27, Issue:4

    Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Glutamine; Haploinsufficiency; Humans; Mice; Mice, Knockout; Sirtuin 1

2017
Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.
    Journal of experimental & clinical cancer research : CR, 2008, Sep-30, Volume: 27

    Topics: Aged; Asian People; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Genetic; Smoking

2008
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
    Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors

2010
Oxidative stress, Helicobacter pylori, and OGG1 Ser326Cys, XPC Lys939Gln, and XPD Lys751Gln polymorphisms in a Turkish population with colorectal carcinoma.
    Genetic testing and molecular biomarkers, 2010, Volume: 14, Issue:4

    Topics: Adult; Aged; Amino Acid Substitution; Colorectal Neoplasms; Cysteine; DNA Glycosylases; DNA-Binding Proteins; Genetics, Population; Glutamine; Helicobacter Infections; Helicobacter pylori; Humans; Lysine; Middle Aged; Mutation, Missense; Oxidative Stress; Polymorphism, Single Nucleotide; Serine; Turkey; Xeroderma Pigmentosum Group D Protein

2010
Novel molecular anti-colorectalcancer conjugate:chlorambucil-adipic acid dihydrizide-glutamine.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:9

    Topics: Adipates; Animals; Antineoplastic Agents; Cell Death; Cell Proliferation; Cell Survival; Chlorambucil; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glutamine; HT29 Cells; Humans; Mice; Molecular Structure; Molecular Targeted Therapy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tumor Cells, Cultured

2013
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured

2003
Interorgan amino acid exchange in humans: consequences for arginine and citrulline metabolism.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:1

    Topics: Adult; Aged; Arginine; Blood Flow Velocity; Citrulline; Colorectal Neoplasms; Female; Glutamine; Hepatectomy; Humans; Intestine, Small; Kidney; Liver; Male; Middle Aged; Organ Specificity; Ornithine

2007
Effect of an immunonutrient mix on human colorectal adenocarcinoma cell growth and viability.
    Nutrition (Burbank, Los Angeles County, Calif.), 2007, Volume: 23, Issue:9

    Topics: Adenocarcinoma; Analysis of Variance; Apoptosis; Arginine; Caco-2 Cells; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fatty Acids, Omega-3; Flow Cytometry; Glutamine; Growth Inhibitors; Humans; RNA

2007
Glutamine supplementation in colorectal cancer.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2007, Volume: 9, Issue:9

    Topics: Colorectal Neoplasms; Food, Formulated; Glutamine; Humans; Postoperative Complications; Time Factors; Treatment Outcome

2007
Are bioavailable glutamine and sensitivity to hydrochloric acid DNA denaturation important colorectal tumour characteristics?
    Biochemical Society transactions, 1994, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Adenoma, Villous; Bromodeoxyuridine; Cell Differentiation; Colorectal Neoplasms; DNA, Neoplasm; Glutamine; Humans; Tumor Cells, Cultured

1994
Phorbol esters rapidly attenuate glutamine uptake and growth in human colon carcinoma cells.
    The Journal of surgical research, 2000, May-15, Volume: 90, Issue:2

    Topics: Arginine; beta-Alanine; Biological Transport; Carcinogens; Cell Division; Colorectal Neoplasms; Glutamine; HT29 Cells; Humans; Intestinal Mucosa; Leucine; Protein Kinase C; Tetradecanoylphorbol Acetate

2000
Inheritance of the 194Trp and the 399Gln variant alleles of the DNA repair gene XRCC1 are associated with increased risk of early-onset colorectal carcinoma in Egypt.
    Cancer letters, 2000, Oct-16, Volume: 159, Issue:1

    Topics: Adult; Age of Onset; Alleles; Amino Acid Sequence; Case-Control Studies; Colorectal Neoplasms; DNA; DNA Repair; DNA-Binding Proteins; Egypt; Female; Gene Frequency; Genetic Variation; Genotype; Glutamine; Humans; Male; Middle Aged; Odds Ratio; Pilot Projects; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors; Rural Population; Tryptophan; Urban Population; X-ray Repair Cross Complementing Protein 1

2000
Growth of colorectal carcinoma cells: regulation in vitro by gastrin, pentagastrin and the gastrin-receptor antagonist proglumide.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:4

    Topics: Animals; Carcinoembryonic Antigen; Carcinoma; Cell Division; Colorectal Neoplasms; Gastrins; Glutamine; Humans; Mice; Pentagastrin; Proglumide; Receptors, Cholecystokinin; Tumor Cells, Cultured

1989