Compounds > glutamine

glutamine and Colonic Neoplasms

glutamine has been researched along with Colonic Neoplasms in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199018 (26.47)18.7374
1990's10 (14.71)18.2507
2000's13 (19.12)29.6817
2010's15 (22.06)24.3611
2020's12 (17.65)2.80

Authors

AuthorsStudies
Almorsy, WA; Arab, HH; Kabel, AM; Khafagy, ES; Naguib, TM; Sabry, NM1
Baiocco, G; Guardamagna, I; Iaria, O; Ivaldi, GB; Liotta, M; Lonati, L; Maggi, M; Mentana, A; Pessino, G; Previtali, A; Scotti, C; Tabarelli de Fatis, P; Uggè, V1
Fan, Q; Hanse, EA; Kong, M; Lowman, XH; Ruiz, BI; Wang, T; Wu, H; Yang, Y1
Arroyo, A; Sánchez-Guillén, L1
Cheng, H; He, W; He, Y; Jie, Q; Li, L; Shen, W; Sun, D; Tan, J; Tao, W; Yang, Y; Zhang, F; Zhu, W1
Gao, M; Han, W; Sun, Y; Wang, K; Wang, X; Wang, Z; Xu, X; Yan, H; Yang, DH; Zhang, H; Zhang, J; Zhou, Y1
Dueñas-Gonzalez, A; Schcolnik-Cabrera, A1
Bajor, DL; Chen, Y; Selfridge, JE; Wang, Z; Zhao, Y1
Board, M; Boultwood, J; Callaghan, R; De Souza, D; McConville, M; Pellagatti, A; Smith, H; Tull, D1
Jia, Z; Li, A; Tian, Q; Wu, H; Xie, Y; Yang, Z; Zhang, H; Zhang, X; Zhang, Z1
Ding, J; Gou, Q; Hou, Y; Jia, X; Jin, J; Liu, Q; Shi, J1
Al-Taie, A; Koseoglu, A1
Aziz, N; Chen, D; Feng, L; Jin, H; Li, J; Song, P; Wang, X; Xu, W; Zhang, Y; Zhou, Q; Zhu, L1
Gendo, Y; Hidano, S; Hirose, H; Kamiyama, N; Kobayashi, T; Mizukami, K; Murakami, K; Noguchi, K; Ozaka, S; Ozaki, T; Sachi, N; Saechue, B; Sakai, K; Sonoda, A1
Fuchs, V; Gebert, J; Katzenmaier, EM; Kopitz, J; Schnölzer, M; Warnken, U1
Bolz, C; Gerhard, M; Javed, S; Kalali, B; Mejías-Luque, R1
Akagi, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H; Ushijima, M1
Cui, Y; Hu, L; Jing, L; Liu, YJ; Wu, YM1
Forbes, NS; Kasinskas, RW; Venkatasubramanian, R1
Fan, Y; Li, Z; Wu, H; Yang, P; Zhang, L1
Boyd, K; Buck, JR; Harris, BK; Hassanein, M; Hight, MR; Hoeksema, MD; Manning, HC; Massion, PP; Nickels, ML; Tantawy, MN1
Bae, DJ; Kim, HJ; Kim, SY; Myung, SJ; Park, S; Ryu, YM1
Budczies, J1
Cai, Z; Li, S; Li, X; Qian, Y; Shen, Y; Tang, Z; Wong, CC; Wu, J; Xu, J; Yang, Z; Yu, J1
Andriamihaja, M; Blachier, F; Chaumontet, C; Tome, D1
Baracos, VE; Dieleman, LA; Field, CJ; Le Roy, S; Sawyer, MB; Xue, H1
Barouki, R; Benelli, C; Blouin, JM; Bortoli, S; Collinet, M; Coumoul, X; Forest, C; Laurent-Puig, P; Nacfer, M; Penot, G1
Cuezva, JM; Sánchez-Aragó, M1
Austin, S; Bazile, M; Blouin, MJ; Javeshghani, S; Pollak, MN; St-Pierre, J; Topisirovic, I; Zakikhani, M1
Boterberg, T; Ceelen, W; Claeys, G; de Hemptinne, B; de Neve, W; El-Malt, M; Pattyn, P1
Cao, J; Chen, Y; Sun, Q; Tang, D; Wei, J; Xiao, L; Zhao, X; Zhu, M1
Blachier, F; Delpal, S; Mayeur, C; Mouillé, B1
Avissar, NE; Ray, EC; Salloum, R; Sax, HC1
Araki, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H1
Alimonti, A; Carver, BS; Chen, Z; Chi, SG; Cordon-Cardo, C; Erdjument-Bromage, H; Jiang, X; Kim, HJ; Misteli, T; Pandolfi, PP; Pavletich, NP; Tempst, P; Teruya-Feldstein, J; Trotman, LC; Wang, X; Yang, H1
Baracos, VE; Dieleman, LA; Field, CJ; Sawyer, MB; Xue, H1
Baracos, VE; Dieleman, LA; Field, CJ; Murray, D; Sawyer, MB; Xue, H1
Arakawa, M; Ardalan, B; Cooney, DA; Jayaram, H; Villacorte, D1
Aoki, T; Morris, HP; Weber, G1
Feuer, L; Gergely, P; Kalmár, L; Láng, I; Nèkám, K; Török, K1
Durrant, L; Ladányi, A; Ma, Y; Price, MR; Sekowski, M; Tendler, SJ; Uray, K1
Blachier, F; Duée, PH; M'Rabet-Touil, H; Robert, V; Selamnia, M1
Basson, MD; Hong, F; Madri, JA; Rashid, Z; Turowski, GA1
Bartolo, DC; Carter, DC; Falconer, JS; Fearon, KC; Garden, OJ; O'Riordain, MG; Rogers, P; Ross, JA1
Bakker, A; Finkelstein, SD; Sayegh, R; Swalsky, P1
Grossie, VB1
Duffy, MM; Fitzpatrick, JM; Harrington, MG; O'Connell, PR; Regan, MC1
Chapkin, RS; Lupton, JR; Wu, G; Zhang, J1
Al-Zoubi, A; Boucher, J; Savarese, D1
Abbiati, R; Barletta, E; D'Agostino, L; Daniele, B; De Martino, S; De Vivo, R; Gallo, C; Perrone, F; Pignata, S; Tambaro, R1
Baumgartner, G; Cosentini, E; Haberl, I; Hamilton, G; Mallinger, R; Pertschy, P; Teleky, B; Wenzl, E1
Pan, M; Souba, WW; Stevens, BR1
Copeland, EM; Souba, WW1
Albers, S; Fürst, P; Stehle, P1
Albers, S; Fürst, P; Lawin, P; Mertes, N; Puchstein, C; Stehle, P; Zander, J1
Schusdziarra, V1
Denis, C; Murat, JC; Trocheris, V; Viallard, V1
Holm, E; Leweling, H; Ritz, R; Saeger, HD; Striebel, JP1
Smith, JP; Solomon, TE1
Clark, CC; Iozzo, RV1
Beauchamp, RD; Glass, EJ; Singh, P; Thompson, JC; Townsend, CM1
Huber, KR; Roberts, J; Rosenfeld, H1
Huber, KR; Mayer, EP; Mitchell, DF; Roberts, J1
Beauchamp, RD; Le, S; Singh, P; Thompson, JC; Townsend, CM1
Bading, JR; Benua, RS; Daly, JM; Gelbard, AS; Ridge, JA1
Alderman, EM; Fett, JW; Lobb, RR1
Aoki, T; Eble, JN; Glover, JL; Sebolt, JS; Weber, G1
Eble, JN; Emrani, J; Faderan, MA; Glover, JL; Lui, MS; Natsumeda, Y; Reardon, MA; Weber, G1

Reviews

2 review(s) available for glutamine and Colonic Neoplasms

ArticleYear
[Metabolome analysis of solid tumors].
    Der Pathologe, 2016, Volume: 37, Issue:Suppl 2

    Topics: 4-Aminobutyrate Transaminase; beta-Alanine; Biomarkers, Tumor; Breast; Breast Neoplasms; Colonic Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutaminase; Glutamine; Humans; Metabolome; Neoplasms; Neoplasms, Hormone-Dependent; Ovarian Neoplasms; Ovary

2016
Evidence for a nutritional need for glutamine in catabolic patients.
    Kidney international. Supplement, 1989, Volume: 27

    Topics: Animals; Carcinoma; Colonic Neoplasms; Dipeptides; Glutamine; Humans; Infusions, Intravenous; Muscles; Nutritional Requirements; Parenteral Nutrition; Reference Values; Stress, Physiological; Wounds and Injuries

1989

Trials

7 trial(s) available for glutamine and Colonic Neoplasms

ArticleYear
Ameliorative Potential of L-Alanyl L-Glutamine Dipeptide in Colon Cancer Patients Receiving Modified FOLFOX-6 Regarding the Incidence of Diarrhea, the Treatment Response, and Patients' Survival: A Randomized Controlled Trial.
    Medicina (Kaunas, Lithuania), 2022, Mar-07, Volume: 58, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Dipeptides; Fluorouracil; Glutamine; Humans; Incidence; Leucovorin; Organoplatinum Compounds; Quality of Life

2022
Potential therapeutic effects of different mouthwashes for alleviation and treatment of oral complications of 5-fluorouracil-based chemotherapy in patients with colon cancer.
    European journal of hospital pharmacy : science and practice, 2023, Volume: 30, Issue:4

    Topics: Benzydamine; Colonic Neoplasms; Fluorouracil; Glutamine; Humans; Mouthwashes; Pain; Prospective Studies; Quality of Life; Sodium Bicarbonate; Stomatitis; Xerostomia

2023
Intravenous alanyl-L-glutamine balances glucose-insulin homeostasis and facilitates recovery in patients undergoing colonic resection: a randomised controlled trial.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:4

    Topics: Adult; Aged; Blood Glucose; Colonic Neoplasms; Dipeptides; Female; Glutamine; Homeostasis; Humans; Insulin; Insulin Resistance; Length of Stay; Male; Middle Aged; Postoperative Period; Prospective Studies

2014
[Impact of glutamine of gut permeability and clinical prognosis on the aging patients undergoing gastric-intestinal operation].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2000, Volume: 22, Issue:5

    Topics: Aged; Aged, 80 and over; Cell Membrane Permeability; Colonic Neoplasms; Digestive System Surgical Procedures; Double-Blind Method; Female; Glutamine; Humans; Intestinal Mucosa; Male; Middle Aged; Parenteral Nutrition, Total; Stomach Neoplasms; Treatment Outcome

2000
Glutamine-supplemented total parenteral nutrition enhances T-lymphocyte response in surgical patients undergoing colorectal resection.
    Annals of surgery, 1994, Volume: 220, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cells, Cultured; Colectomy; Colonic Neoplasms; DNA; Elective Surgical Procedures; Female; Glutamine; Humans; Interleukin-2; Interleukin-6; Lipopolysaccharides; Male; Middle Aged; Nitrogen; Parenteral Nutrition, Total; Phytohemagglutinins; Prospective Studies; T-Lymphocytes; Tumor Necrosis Factor-alpha

1994
Oral glutamine in the prevention of fluorouracil induced intestinal toxicity: a double blind, placebo controlled, randomised trial.
    Gut, 2001, Volume: 48, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Diarrhea; Double-Blind Method; Female; Fluorouracil; Glutamine; Humans; Intestinal Absorption; Male; Middle Aged; Statistics, Nonparametric

2001
Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery.
    Lancet (London, England), 1989, Feb-04, Volume: 1, Issue:8632

    Topics: Clinical Trials as Topic; Colonic Neoplasms; Dipeptides; Female; Glutamine; Humans; Male; Middle Aged; Muscles; Nitrogen; Parenteral Nutrition, Total; Postoperative Period; Random Allocation; Rectal Neoplasms

1989

Other Studies

59 other study(ies) available for glutamine and Colonic Neoplasms

ArticleYear
Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53
    International journal of molecular sciences, 2023, Feb-03, Volume: 24, Issue:3

    Topics: Asparaginase; Asparagine; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Glutamine; Humans; Radiation, Ionizing; Tumor Suppressor Protein p53

2023
Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia.
    Genes, 2023, 09-19, Volume: 14, Issue:9

    Topics: Animals; Cachexia; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Glutamine; Histone Code; Histone Methyltransferases; Histones; Humans; Ketoglutaric Acids; Mice; Tumor Microenvironment; TWEAK Receptor

2023
Immunonutrition in patients with colon cancer.
    Immunotherapy, 2020, Volume: 12, Issue:1

    Topics: Arginine; Colonic Neoplasms; Dietary Supplements; Evidence-Based Medicine; Fatty Acids; Glutamine; Humans; Immunomodulation; Nutritional Physiological Phenomena; Postoperative Complications

2020
Lobetyolin induces apoptosis of colon cancer cells by inhibiting glutamine metabolism.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:6

    Topics: Amino Acid Transport System ASC; Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Cell Line, Tumor; Colonic Neoplasms; Glutamine; HCT116 Cells; Humans; Mice; Mice, Nude; Minor Histocompatibility Antigens; Polyynes; Toluene; Tumor Suppressor Protein p53

2020
Quercetin overcomes colon cancer cells resistance to chemotherapy by inhibiting solute carrier family 1, member 5 transporter.
    European journal of pharmacology, 2020, Aug-15, Volume: 881

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Glutamine; Humans; Metabolomics; Quercetin; Sodium-Glucose Transporter 1

2020
Mouse Model for Efficient Simultaneous Targeting of Glycolysis, Glutaminolysis, and De Novo Synthesis of Fatty Acids in Colon Cancer.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2174

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Diazooxonorleucine; Drug Screening Assays, Antitumor; Fatty Acid Synthase, Type I; Fatty Acids; Female; Glutaminase; Glutamine; Glycolysis; Hexokinase; Indazoles; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Orlistat; Smegmamorpha

2021
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
    Journal of genetics and genomics = Yi chuan xue bao, 2020, 07-20, Volume: 47, Issue:7

    Topics: Animals; Benzeneacetamides; Cell Line, Tumor; Colonic Neoplasms; Glutaminase; Glutamine; Heterografts; Humans; Mice; Thiadiazoles

2020
The utilisation of glutamine and glucose by a 3-D tumour model trapped in quiescence.
    The international journal of biochemistry & cell biology, 2021, Volume: 133

    Topics: Cell Proliferation; Colonic Neoplasms; Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Microenvironment

2021
Integration of transcriptomics and metabolomics reveals anlotinib-induced cytotoxicity in colon cancer cells.
    Gene, 2021, Jun-20, Volume: 786

    Topics: Aspartic Acid; Cell Cycle Proteins; Chondroitin Sulfate Proteoglycans; Chromatography, Liquid; Chromosomal Proteins, Non-Histone; Colonic Neoplasms; DNA Topoisomerases, Type II; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glutamine; Glycogen Phosphorylase; HCT116 Cells; Humans; Indoles; Metabolomics; Poly-ADP-Ribose Binding Proteins; Quinolines; Sequence Analysis, RNA; Tandem Mass Spectrometry

2021
AMPK phosphorylates PPARδ to mediate its stabilization, inhibit glucose and glutamine uptake and colon tumor growth.
    The Journal of biological chemistry, 2021, Volume: 297, Issue:3

    Topics: Adenylate Kinase; Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Glucose; Glutamine; Heterografts; Humans; Mice, Nude; Phosphorylation; PPAR gamma

2021
Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Asparagine; Autophagy; Cell Line, Tumor; Colonic Neoplasms; Glutamine; HEK293 Cells; Humans; Signal Transduction; Sulfides; Thiadiazoles

2017
Oral administration of antibiotics results in fecal occult bleeding due to metabolic disorders and defective proliferation of the gut epithelial cell in mice.
    Genes to cells : devoted to molecular & cellular mechanisms, 2018, Volume: 23, Issue:12

    Topics: Administration, Oral; Ampicillin; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Butyric Acid; Carbohydrate Metabolism; Cecum; Cell Line, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Cytokines; Epithelial Cells; Glutamine; Lipid Metabolism; Macrophages; Metabolic Diseases; Metabolome; Metagenomics; Mice; Microbiota; Occult Blood; RAW 264.7 Cells; Regeneration; Sodium Glutamate; Species Specificity; Vancomycin

2018
Deciphering the galectin-12 protein interactome reveals a major impact of galectin-12 on glutamine anaplerosis in colon cancer cells.
    Experimental cell research, 2019, 06-15, Volume: 379, Issue:2

    Topics: Amino Acid Transport System ASC; Apoptosis; Cell Differentiation; Colon; Colonic Neoplasms; Galectins; Glutamine; Humans; Minor Histocompatibility Antigens; Tumor Cells, Cultured

2019
Helicobacter bilis gamma-glutamyltranspeptidase enhances inflammatory stress response via oxidative stress in colon epithelial cells.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Cell Line, Tumor; Colon; Colonic Neoplasms; Cyclic AMP Response Element-Binding Protein; gamma-Glutamyltransferase; Glutamine; Helicobacter; Helicobacter Infections; Humans; Interleukin-8; Intestinal Mucosa; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Transcription Factor AP-1; Transcriptional Activation

2013
Demethylation effect of the antineoplaston AS2-1 on genes in colon cancer cells.
    Oncology reports, 2014, Volume: 31, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; DNA Methylation; Down-Regulation; Drug Combinations; Estrogen Receptor alpha; Gene Expression; Glutamine; HCT116 Cells; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mucin-2; Phenylacetates; Promoter Regions, Genetic; RNA, Messenger

2014
Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture.
    Integrative biology : quantitative biosciences from nano to macro, 2014, Volume: 6, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypoxia; Kinetics; Lactic Acid; Microscopy, Fluorescence; Models, Theoretical

2014
PKM2 depletion induces the compensation of glutaminolysis through β-catenin/c-Myc pathway in tumor cells.
    Cellular signalling, 2014, Volume: 26, Issue:11

    Topics: Antimetabolites; beta Catenin; Carrier Proteins; Cell Survival; Colonic Neoplasms; Deoxyglucose; Glutamine; Glycolysis; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Membrane Proteins; MicroRNAs; Proto-Oncogene Proteins c-myc; Pyruvate Kinase; RNA, Neoplasm; Signal Transduction; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014
Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer.
    Molecular imaging and biology, 2016, Volume: 18, Issue:1

    Topics: Amino Acid Transport System ASC; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colonic Neoplasms; ErbB Receptors; Female; Glutamine; Humans; Lung Neoplasms; Male; Mice, Nude; Minor Histocompatibility Antigens; Mutation; Positron-Emission Tomography; Xenograft Model Antitumor Assays

2016
Mitochondria-targeting ratiometric fluorescent probe for γ-glutamyltranspeptidase and its application to colon cancer.
    Chemical communications (Cambridge, England), 2016, Aug-16, Volume: 52, Issue:68

    Topics: Animals; Colonic Neoplasms; Fluorescence; Fluorescent Dyes; gamma-Glutamyltransferase; Glutamine; HCT116 Cells; Humans; Hydrolysis; Indoles; Limit of Detection; Mice; Mitochondria

2016
Determination of amino acids in colon cancer cells by using UHPLC-MS/MS and [U-
    Talanta, 2017, Jan-01, Volume: 162

    Topics: Amino Acids; Carbon Isotopes; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colonic Neoplasms; Glutamine; Humans; Radioactive Tracers; Reproducibility of Results; Tandem Mass Spectrometry

2017
Butyrate metabolism in human colon carcinoma cells: implications concerning its growth-inhibitory effect.
    Journal of cellular physiology, 2009, Volume: 218, Issue:1

    Topics: Acetic Acid; Adenine Nucleotides; Adenocarcinoma; Bacteria; Butyrates; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Glutamine; Growth Inhibitors; Histones; Humans; Intestine, Large; Lipid Metabolism; Malates; Nuclear Proteins; Oxidation-Reduction

2009
Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward colo
    The British journal of nutrition, 2009, Volume: 102, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Camptothecin; Colonic Neoplasms; Combined Modality Therapy; Diarrhea; Dietary Supplements; Fatty Acids, Omega-3; Female; Fluorouracil; Glutamine; Immune Tolerance; Irinotecan; Leukocyte Count; Nutritional Status; Rats; Rats, Inbred F344; Treatment Failure; Xenograft Model Antitumor Assays

2009
Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex.
    International journal of cancer, 2011, Jun-01, Volume: 128, Issue:11

    Topics: Adenocarcinoma; Blotting, Western; Butyrates; Cell Differentiation; Cell Proliferation; Chromatin Immunoprecipitation; Colonic Neoplasms; Glucose; Glutamine; Glycolysis; Histone Deacetylases; Histones; Humans; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2011
The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil.
    Journal of translational medicine, 2011, Feb-08, Volume: 9

    Topics: Adenosine Triphosphate; Blotting, Western; Cell Death; Colonic Neoplasms; Energy Metabolism; Fluorouracil; Glutamine; HCT116 Cells; Humans; Iodoacetates; Pyruvates; Remission Induction; Signal Transduction

2011
Carbon source and myc expression influence the antiproliferative actions of metformin.
    Cancer research, 2012, Dec-01, Volume: 72, Issue:23

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Carbon; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Glucose; Glutamine; Hypoglycemic Agents; Metformin; Mice; Mice, Inbred C57BL; Phosphorylation; Proto-Oncogene Proteins c-myc

2012
Does the addition of glutamine to total parenteral nutrition have beneficial effect on the healing of colon anastomosis and bacterial translocation after preoperative radiotherapy?
    American journal of clinical oncology, 2003, Volume: 26, Issue:3

    Topics: Anastomosis, Surgical; Animals; Bacterial Translocation; Colon; Colonic Neoplasms; Glutamine; Male; Parenteral Nutrition, Total; Radiation Injuries, Experimental; Radiotherapy; Rats; Rats, Wistar; Wound Healing

2003
Inhibition of human colon carcinoma cell growth by ammonia: a non-cytotoxic process associated with polyamine synthesis reduction.
    Biochimica et biophysica acta, 2003, Dec-05, Volume: 1624, Issue:1-3

    Topics: Ammonia; Ammonium Chloride; Biogenic Polyamines; Cell Cycle; Cell Differentiation; Cell Division; Colonic Neoplasms; Glutamine; HT29 Cells; Humans; Protein Biosynthesis; Putrescine

2003
Growth hormone and epidermal growth factor upregulate specific sodium-dependent glutamine uptake systems in human intestinal C2BBe1 cells.
    The Journal of nutrition, 2005, Volume: 135, Issue:1

    Topics: Biological Transport; Cell Line; Cell Line, Tumor; Colonic Neoplasms; Epidermal Growth Factor; Glutamine; Human Growth Hormone; Humans; Intestinal Mucosa; Kinetics; Sodium

2005
Effects of antineoplaston AS2-1 against post-operative lung metastasis in orthotopically implanted colon cancer in nude rat.
    Oncology reports, 2005, Volume: 13, Issue:3

    Topics: Animals; Carcinoma; Colonic Neoplasms; Drug Combinations; G1 Phase; Glutamine; In Situ Nick-End Labeling; Lung Neoplasms; Male; Neoplasms, Experimental; Phenylacetates; Rats; Rats, Inbred F344

2005
Ubiquitination regulates PTEN nuclear import and tumor suppression.
    Cell, 2007, Jan-12, Volume: 128, Issue:1

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Cell Nucleus; Colonic Neoplasms; Endosomal Sorting Complexes Required for Transport; Glutamine; Hamartoma Syndrome, Multiple; Humans; Lysine; Mice; Molecular Sequence Data; Mutant Proteins; Mutation; Nedd4 Ubiquitin Protein Ligases; Neoplasm Staging; Polyps; Protein Structure, Secondary; Protein Transport; PTEN Phosphohydrolase; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases

2007
Nutritional modulation of antitumor efficacy and diarrhea toxicity related to irinotecan chemotherapy in rats bearing the ward colon tumor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Dec-01, Volume: 13, Issue:23

    Topics: Animals; Camptothecin; Colonic Neoplasms; Diarrhea; Diet; Fatty Acids, Omega-3; Female; Food-Drug Interactions; Glutamine; Irinotecan; Oligosaccharides; Probiotics; Rats

2007
Bolus oral glutamine protects rats against CPT-11-induced diarrhea and differentially activates cytoprotective mechanisms in host intestine but not tumor.
    The Journal of nutrition, 2008, Volume: 138, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Colon; Colonic Neoplasms; Cytoprotection; Diarrhea; Female; Glutamine; Irinotecan; Neoplasms, Experimental; Rats

2008
Effect of L-glutamine antagonists on 5-phosphoribosyl 1-pyrophosphate levels in P388 leukemia and in murine colon adenocarcinomas in vivo.
    Biochemical pharmacology, 1982, Apr-15, Volume: 31, Issue:8

    Topics: Adenocarcinoma; Animals; Azaserine; Colonic Neoplasms; Diazooxonorleucine; Glutamine; Intestine, Small; Isoxazoles; Leukemia P388; Leukemia, Experimental; Mice; Neoplasms, Experimental; Pentosephosphates; Phosphoribosyl Pyrophosphate

1982
Regulatory properties and behavior of activity of carbamoyl phosphate synthetase II (glutamine-hydrolyzing) in normal and proliferating tissues.
    The Journal of biological chemistry, 1982, Jan-10, Volume: 257, Issue:1

    Topics: Animals; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Colonic Neoplasms; Glutamine; Humans; Hydrogen-Ion Concentration; Kidney Neoplasms; Kinetics; Ligases; Liver; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Rats; Rats, Inbred ACI; Ribonucleotides

1982
Effect of treatment with glutaurine on human antibody-dependent cell-mediated cytotoxicity (ADCC).
    Immunological communications, 1981, Volume: 10, Issue:6

    Topics: Adult; Aged; Animals; Antibody-Dependent Cell Cytotoxicity; Breast Neoplasms; Colonic Neoplasms; Female; Glutamine; Hodgkin Disease; Humans; Immunoglobulin Fc Fragments; Liver Neoplasms; Lymphocytes; Lymphoma; Male; Middle Aged; Multiple Myeloma; Parathyroid Hormone; Taurine; Urinary Bladder Neoplasms

1981
Immune recognition of human colonic-tumour-associated MUC-2 mucins using an anti-peptide antibody.
    International journal of cancer, 1993, Nov-11, Volume: 55, Issue:5

    Topics: Adsorption; Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Chymotrypsin; Colonic Neoplasms; Concanavalin A; Epitopes; Glutamine; Humans; Immunoblotting; Molecular Sequence Data; Mucin-2; Mucins; Neoplasm Proteins; Trypsin

1993
Metabolism of L-arginine through polyamine and nitric oxide synthase pathways in proliferative or differentiated human colon carcinoma cells.
    Biochimica et biophysica acta, 1995, Sep-21, Volume: 1268, Issue:3

    Topics: Adenocarcinoma; Arginine; Cell Differentiation; Cell Division; Colonic Neoplasms; Dipeptidyl Peptidase 4; Glutamine; Humans; Nitric Oxide Synthase; Ornithine; Polyamines; Putrescine; Tumor Cells, Cultured

1995
Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines.
    Cancer research, 1994, Nov-15, Volume: 54, Issue:22

    Topics: Alkaline Phosphatase; beta-Galactosidase; Cathepsin C; Cell Adhesion; Cell Differentiation; Cell Division; Colonic Neoplasms; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Glutamine; Humans; Integrins; Lactase; Oligo-1,6-Glucosidase; Phenotype; Tumor Cells, Cultured

1994
Determination of tumor aggressiveness in colorectal cancer by K-ras-2 analysis.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:5

    Topics: Adenocarcinoma; Aspartic Acid; Biomarkers, Tumor; Codon; Colonic Neoplasms; DNA, Neoplasm; Exons; Follow-Up Studies; Genes, ras; Glutamine; Histidine; Humans; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Retrospective Studies; Survival Rate; Valine

1993
Citrulline and arginine increase the growth of the Ward colon tumor in parenterally fed rats.
    Nutrition and cancer, 1996, Volume: 26, Issue:1

    Topics: Animals; Arginine; Citrulline; Colonic Neoplasms; Glutamine; Male; Ornithine; Parenteral Nutrition; Rats; Rats, Inbred F344; Taurine; Urea

1996
Metabolic substrate utilization differs in ileal faecal and urinary reservoirs.
    The British journal of surgery, 1998, Volume: 85, Issue:6

    Topics: Butyrates; Carbon Dioxide; Colitis, Ulcerative; Colonic Neoplasms; Glutamine; Humans; Ileum; Intestinal Mucosa; Proctocolectomy, Restorative; Urinary Reservoirs, Continent

1998
Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen.
    The Journal of nutrition, 1998, Volume: 128, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Butyrates; Butyric Acid; Carcinogens; Cellulose; Colon; Colonic Neoplasms; Diet; Energy Metabolism; Glucose; Glutamine; Hydroxybutyrates; Ketone Bodies; Kinetics; Lactic Acid; Male; Oxidation-Reduction; Pectins; Rats; Rats, Sprague-Dawley

1998
Glutamine for irinotecan diarrhea.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:2

    Topics: Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Diarrhea; Female; Glutamine; Humans; Irinotecan; Male; Middle Aged; Rectal Neoplasms

2000
The differentiation inducers phenylacetate and phenylbutyrate modulate camptothecin sensitivity in colon carcinoma cells in vitro by intracellular acidification.
    International journal of oncology, 2001, Volume: 19, Issue:5

    Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Bicarbonates; Camptothecin; Cell Cycle; Cell Differentiation; Cell Survival; Colonic Neoplasms; Drug Resistance, Neoplasm; Glutamine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Phenylacetates; Phenylbutyrates; Tumor Cells, Cultured

2001
Kinetics of the sodium-dependent glutamine transporter in human intestinal cell confluent monolayers.
    Biochemical and biophysical research communications, 1992, Oct-30, Volume: 188, Issue:2

    Topics: Adenocarcinoma; Alanine; Amino Acid Transport Systems, Basic; Amino Acids; Analysis of Variance; Biological Transport; Carrier Proteins; Cations, Monovalent; Colonic Neoplasms; Glutamine; Humans; Kinetics; Sodium; Tumor Cells, Cultured

1992
Cytokine modulation of Na(+)-dependent glutamine transport across the brush border membrane of monolayers of human intestinal Caco-2 cells.
    Annals of surgery, 1992, Volume: 215, Issue:5

    Topics: Adenocarcinoma; Biological Transport, Active; Colonic Neoplasms; Cytokines; Dexamethasone; Endotoxins; Glutamine; Humans; In Vitro Techniques; Microvilli; Sodium; Tumor Cells, Cultured

1992
[Gastrointestinal hormones and cancers of the gastrointestinal tract].
    Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Colonic Neoplasms; DNA Replication; Gastrins; Glutamine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Proglumide; Somatostatin; Tumor Cells, Cultured

1989
Effect of glutamine deprivation and glutamate or ammonium chloride addition on growth rate, metabolism and differentiation of human colon cancer cell-line HT29.
    The International journal of biochemistry, 1986, Volume: 18, Issue:3

    Topics: Ammonium Chloride; Cell Differentiation; Cell Division; Cell Line; Colonic Neoplasms; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycogen; Humans; Lactates; Microscopy, Electron

1986
[Amino acid uptake and release by colorectal cancer in man].
    Infusionstherapie und klinische Ernahrung, 1986, Volume: 13, Issue:2

    Topics: Aged; Amino Acids; Colonic Neoplasms; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Ornithine; Rectal Neoplasms; Tyrosine

1986
Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer.
    Gastroenterology, 1988, Volume: 95, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Gastrins; Glutamine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Proglumide; Somatostatin; Tumor Cells, Cultured

1988
Modulation of heparan sulfate biosynthesis. Effects of 6-diazo-5-oxo-L-norleucine and low glutamine on the synthesis of heparan sulfate proteoglycan by human colon carcinoma cells.
    The Journal of biological chemistry, 1987, Aug-15, Volume: 262, Issue:23

    Topics: Azo Compounds; Cell Division; Cells, Cultured; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chondroitin Sulfate Proteoglycans; Colonic Neoplasms; Diazooxonorleucine; Electrophoresis, Polyacrylamide Gel; Glucosamine; Glutamine; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Hexosamines; Microscopy, Electron; Oligosaccharides; Protein Biosynthesis; Proteoglycans; Sulfates

1987
Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice.
    Annals of surgery, 1985, Volume: 202, Issue:3

    Topics: Adenocarcinoma; Animals; Body Weight; Cell Division; Cell Line; Colon; Colonic Neoplasms; Gastric Fundus; Gastrins; Glutamine; Mice; Organ Size; Pancreas; Proglumide; Receptors, Cell Surface

1985
Uptake of glutamine antimetabolites 6-diazo-5-oxo-L-norleucine (DON) and acivicin in sensitive and resistant tumor cell lines.
    International journal of cancer, 1988, May-15, Volume: 41, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Azo Compounds; Biological Transport; Colonic Neoplasms; Diazooxonorleucine; Drug Resistance; Glutamine; Humans; Isoxazoles; Kinetics; Leukemia P388; Lung Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Tumor Cells, Cultured

1988
Cell cycle phase perturbations by 6-diazo-5-oxo-L-norleucine and acivicin in normal and neoplastic human cell lines.
    British journal of cancer, 1987, Volume: 55, Issue:6

    Topics: Antimetabolites; Azo Compounds; Cell Cycle; Cell Line; Colonic Neoplasms; Diazooxonorleucine; Drug Evaluation, Preclinical; Glutaminase; Glutamine; Humans; Isoxazoles; Lung Neoplasms; Neoplasms, Experimental; Oxazoles

1987
Inhibition of pentagastrin-stimulated up-regulation of gastrin receptors and growth of mouse colon tumor in vivo by proglumide, a gastrin receptor antagonist.
    Cancer research, 1987, Oct-01, Volume: 47, Issue:19

    Topics: Animals; Colon; Colonic Neoplasms; Gastrins; Glutamine; Male; Mice; Pentagastrin; Proglumide; Receptors, Cholecystokinin

1987
Perfusion of colorectal hepatic metastases. Relative distribution of flow from the hepatic artery and portal vein.
    Cancer, 1987, May-01, Volume: 59, Issue:9

    Topics: Adult; Aged; Colonic Neoplasms; Female; Glutamine; Humans; Liver Neoplasms; Male; Middle Aged; Radionuclide Imaging; Rectal Neoplasms; Regional Blood Flow; Technetium Tc 99m Aggregated Albumin; Technetium Tc 99m Sulfur Colloid

1987
Isolation of tumor-secreted products from human carcinoma cells maintained in a defined protein-free medium.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:17

    Topics: Carcinoembryonic Antigen; Carcinoma; Cell Line; Colonic Neoplasms; Culture Media; Fibrosarcoma; Glutamine; Growth Substances; Humans; Lung Neoplasms; Muramidase; Proteins

1985
Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma.
    Biochemical pharmacology, 1985, Jan-01, Volume: 34, Issue:1

    Topics: Antibiotics, Antineoplastic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Colon; Colonic Neoplasms; Glutamine; Humans; Isoxazoles; Kinetics; Ligases; Oxazoles

1985
Purine enzymology of human colon carcinomas.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Colon; Colonic Neoplasms; Glutamine; Humans; Intestinal Mucosa; Male; Purines

1985