Compounds > glutamine

glutamine and Bipolar Disorder

glutamine has been researched along with Bipolar Disorder in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.04)18.7374
1990's1 (2.04)18.2507
2000's23 (46.94)29.6817
2010's17 (34.69)24.3611
2020's7 (14.29)2.80

Authors

AuthorsStudies
Barbini, B; Benedetti, F; Bravi, B; Dallaspezia, S; Melloni, EMT; Poletti, S; Zanardi, R1
Allauze, E; Chabert, J; Chassain, C; De Chazeron, I; Fossati, P; Llorca, PM; Pereira, B; Rotgé, JY; Samalin, L1
Bhargava, R; Chadda, RK; Gupta, R; Jagannathan, NR; Sharma, U; Sood, M1
Honda, S; Horita, N; Ino, H; Meyer, JH; Mimura, M; Moriguchi, S; Nakajima, S; Noda, Y; Tsugawa, S; Yamada, K; Yoshida, K1
Andrews, HF; Baldinger, A; Casadei, S; Fader, KM; Feng, M; Gibbs, RA; Gulsuner, S; Gur, RC; King, MC; Korchina, V; Majara, L; Malan, M; McClellan, JM; Mndini, MM; Mqulwana, SG; Muzny, D; Nagdee, M; Ngqengelele, LL; Ntola, OA; Pretorius, A; Ramesar, RS; Sibeko, G; Stein, DJ; Susser, ES; van der Merwe, C; Walsh, T; Willoughby, E; Zingela, Z1
Alvarez-Vazquez, C; Gonzalez-Blanco, L; Jimenez-Trevino, L; Rodriguez-Revuelta, J; Saiz Martinez, PA1
Aryutova, K; Kandilarova, S; Paunova, R; Stoyanov, D; Todeva-Radneva, A1
Galińska-Skok, B; Gierus, J; Marcinowicz, P; Mosiolek, A; Szulc, A; Waszkiewicz, N; Wiedlocha, M1
Horne, CM; Jelen, LA; King, S; Lythgoe, DJ; Stone, JM; Young, AH1
Bustillo, JR; Chavez, L; Gasparovic, C; Jones, T; Lenroot, RK; Lin, D; Qualls, C1
Chavez, S; Kolla, NJ; Lobaugh, NJ; Meyer, JH; Smaragdi, A1
Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M1
Chitty, KM; Hermens, DF; Hickie, IB; Lagopoulos, J; Lee, RS1
Gigante, AD; Lafer, B; Yatham, LN1
Taylor, MJ1
Ågren, H; Ekman, CJ; Fujita, Y; Hashimoto, K; Jakobsson, J; Landén, M; Pålsson, E; Sellgren, C; Södersten, K1
Carvalho, AF; De Sousa, RT; Gattaz, WF; Leite, CC; Machado-Vieira, R; Otaduy, MC; Soeiro-de-Souza, MG; Zanetti, MV1
da Costa Leite, C; Henning, A; Machado-Vieira, R; Moreno, RA; Otaduy, MC; Pastorello, BF; Soeiro-de-Souza, MG; Vallada, H1
Bond, DJ; da Silveira, LE; Honer, WG; Lam, RW; Lang, DJ; MacMillan, EL; Su, W; Torres, IJ; Yatham, LN1
Bond, DJ; Bücker, J; Kapczinski, F; Kozicky, JM; MacMillan, EL; Muralidharan, K; Rosa, AR; Silveira, LE; Yatham, LN1
Funakoshi, Y; Harada, M; Iga, JI; Inoshita, M; Kameoka, N; Kinoshita, M; Kubo, H; Nakataki, M; Nakayama-Yamauchi, C; Numata, S; Ohmori, T; Ohta, M; Sumitani, S; Tamaru, M; Umehara, H; Watanabe, SY1
Guan, JT; Guo, XB; Li, H; Liu, CF; Ou, SM; Shen, ZW; Tan, HZ; Wang, XQ; Wen, CH; Wu, RH; Xu, CT; Zhang, J; Zhang, YN1
Cohen, BM; Jensen, JE; Lundy, M; Öngür, D; Prescot, AP; Renshaw, PF; Stork, C1
Adler, CM; Cecil, KM; DelBello, MP; Patel, NC; Strakowski, SM1
Jensen, JE; Kaufman, RE; Marks, EH; Ostacher, MJ; Pollack, MH; Renshaw, PF; Sachs, GS; Simon, NM1
Cohen, BM; Haws, C; Kim, TS; Lyoo, IK; Renshaw, PF; Yoon, SJ1
Brotman, MA; Dickstein, DP; Knopf, L; Leibenluft, E; Onelio, L; Pine, DS; Rich, BA; Towbin, KE; Van Der Veen, JW1
Erfurth, A; Michael, N; Pfleiderer, B1
Renshaw, PF1
Hall, GB; MacQueen, GM; Milne, AM; Senaratne, R1
Ghanizadeh, A; Mohammadynejad, P; Saadat, I; Saadat, M1
Bond, DJ; Gigante, AD; Lafer, B; Lam, RW; Yatham, LN; Young, LT1
Arolt, V; Erfurth, A; Gössling, M; Heindel, W; Michael, N; Ohrmann, P; Pfleiderer, B1
Dager, SR; Demopulos, C; Dunner, DL; Friedman, SD; Hirashima, F; Lyoo, IK; Parow, A; Renshaw, PF; Stoll, AL1
Barden, N; Gagné, B; Harvey, M; Labbé, M; Raymond, C; Shink, E; Tremblay, M1
Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J1
Ankerst, DP; Yildiz-Yesiloglu, A1
Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Lyoo, IK; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J1
Ashworth, F; Bhagwagar, Z; Cowen, PJ; Evans, J; Jezzard, P; Matthews, PM; Sule, A; Wylezinska, M1
Breeze, JL; Dieterich, M; Finn, CT; Frazier, JA; Frederick, Bd; Glod, CA; Moore, CM; Renshaw, PF1
Marcus, SM; Mrazek, DA; Port, JD; Unal, SS1
Bahn, S; Griffin, JL; Holmes, E; Huang, JT; Lan, MJ; Manji, H; McLoughlin, GA; Tsang, TM; Yuan, P1
Bass, NJ; Choudhury, K; Curtis, D; Gurling, HM; Kosmin, M; Lawrence, J; McQuillin, A; Puri, V1
Dickstein, DP; Knopf, L; Leibenluft, E; Pine, DS; Towbin, KE; van der Veen, JW1
Kloos, A; Weller, EB; Weller, RA1
Mebane, AH1
Crow, TJ; DeLisi, LE; Jain, S; Leggo, J; Paykel, ES; Rubinsztein, DC; Walsh, C1
Gershon, S; Levine, J; McClure, RJ; Panchalingam, K; Pettegrew, JW; Rapoport, A1
Castillo, M; Courvoisie, H; Hooper, SR; Kwock, L1

Reviews

10 review(s) available for glutamine and Bipolar Disorder

ArticleYear
Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies.
    International journal of molecular sciences, 2022, Aug-11, Volume: 23, Issue:16

    Topics: Aspartic Acid; Bipolar Disorder; Depressive Disorder, Major; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy

2022
Glutamatergic Neurometabolite Levels in Bipolar Disorder: A Systematic Review and Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies.
    Biological psychiatry. Cognitive neuroscience and neuroimaging, 2023, Volume: 8, Issue:2

    Topics: Adult; Bipolar Disorder; Child; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Proton Magnetic Resonance Spectroscopy

2023
The Translational Potential of Non-coding RNAs and Multimodal MRI Data Sets as Diagnostic and Differential Diagnostic Biomarkers for Mood Disorders.
    Current topics in medicinal chemistry, 2021, Volume: 21, Issue:11

    Topics: Biomarkers; Bipolar Disorder; Brain; Depressive Disorder, Major; Gene Expression Regulation; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; MicroRNAs; Mood Disorders; RNA, Untranslated

2021
Proton magnetic resonance spectroscopy changes after lithium treatment. Systematic review.
    Psychiatry research. Neuroimaging, 2018, 03-30, Volume: 273

    Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Cross-Sectional Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Lithium Compounds; Proton Magnetic Resonance Spectroscopy; Treatment Outcome

2018
A systematic review and meta-analysis of proton magnetic resonance spectroscopy and mismatch negativity in bipolar disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:11

    Topics: Bipolar Disorder; Evoked Potentials; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Protons

2013
Could glutamate spectroscopy differentiate bipolar depression from unipolar?
    Journal of affective disorders, 2014, Volume: 167

    Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Diagnosis, Differential; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity

2014
Applications for magnetic resonance imaging in bipolar disorder.
    CNS spectrums, 2007, Volume: 12, Issue:6 Suppl 8

    Topics: Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2007
Brain glutamate levels measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta-analysis.
    Bipolar disorders, 2012, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Bipolar Disorder; Brain; Child; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy

2012
Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: a systematic review of the in vivo proton magnetic resonance spectroscopy findings.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy

2006
Biologic basis of bipolar disorder in children and adolescents.
    Current psychiatry reports, 2008, Volume: 10, Issue:2

    Topics: Adolescent; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Child; Energy Metabolism; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Lithium Compounds; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuropsychological Tests

2008

Trials

5 trial(s) available for glutamine and Bipolar Disorder

ArticleYear
1H-magnetic resonance spectroscopy study of glutamate-related abnormality in bipolar disorder.
    Journal of affective disorders, 2017, Jan-15, Volume: 208

    Topics: Adult; Basal Ganglia; Biomarkers; Bipolar Disorder; Case-Control Studies; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged

2017
Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:7

    Topics: Administration, Oral; Adult; Antidepressive Agents; Bipolar Disorder; Brain; Chi-Square Distribution; Cytidine; Double-Blind Method; Glutamic Acid; Glutamine; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Protons; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome; Young Adult

2009
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.
    Journal of child and adolescent psychopharmacology, 2009, Volume: 19, Issue:1

    Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Creatine; Diagnosis, Differential; Double-Blind Method; Female; Glutamine; Humans; Inositol; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Mood Disorders; Single-Blind Method

2009
Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder.
    Biological psychiatry, 2004, Sep-01, Volume: 56, Issue:5

    Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Brain Mapping; Case-Control Studies; Echo-Planar Imaging; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Valproic Acid

2004
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation.
    Psychiatry research, 2008, May-30, Volume: 163, Issue:1

    Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Mapping; Cerebral Cortex; Chronic Disease; Creatine; Diagnosis, Differential; Dominance, Cerebral; Double-Blind Method; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Irritable Mood; Lithium Compounds; Magnetic Resonance Spectroscopy; Mood Disorders; Phosphocreatine

2008

Other Studies

34 other study(ies) available for glutamine and Bipolar Disorder

ArticleYear
Antidepressant chronotherapeutics normalizes prefrontal
    Progress in neuro-psychopharmacology & biological psychiatry, 2022, 12-20, Volume: 119

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Drug Chronotherapy; Glutamic Acid; Glutamine; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy

2022
Neurochemical correlates of cognitive functions in euthymic patients with bipolar disorder:
    Asian journal of psychiatry, 2022, Volume: 78

    Topics: Bipolar Disorder; Cognition; Glutamates; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy

2022
Genetics of schizophrenia in the South African Xhosa.
    Science (New York, N.Y.), 2020, 01-31, Volume: 367, Issue:6477

    Topics: Age Factors; Autistic Disorder; Bipolar Disorder; Dopamine; Female; gamma-Aminobutyric Acid; Genetic Variation; Glutamine; Humans; Male; Mutation; Neural Pathways; Schizophrenia; Sex Factors; South Africa; Synapses; Synaptic Transmission

2020
Glutamine and New Pharmacological Targets to Treat Suicidal Ideation.
    Current topics in behavioral neurosciences, 2020, Volume: 46

    Topics: Bipolar Disorder; Depressive Disorder, Major; Glutamine; Humans; Suicidal Ideation; Suicide

2020
Functional magnetic resonance spectroscopy in patients with schizophrenia and bipolar affective disorder: Glutamate dynamics in the anterior cingulate cortex during a working memory task.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019, Volume: 29, Issue:2

    Topics: Adult; Analysis of Variance; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Schizophrenia; Young Adult

2019
Proton magnetic resonance spectroscopic imaging of gray and white matter in bipolar-I and schizophrenia.
    Journal of affective disorders, 2019, 03-01, Volume: 246

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult

2019
Differential levels of prefrontal cortex glutamate+glutamine in adults with antisocial personality disorder and bipolar disorder: A proton magnetic resonance spectroscopy study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2019, 07-13, Volume: 93

    Topics: Adult; Antisocial Personality Disorder; Bipolar Disorder; Brain; Case-Control Studies; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Neuroimaging; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy

2019
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:8

    Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome

2019
(1)H-MRS of hippocampus in patients after first manic episode.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2014, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Neurons; Prospective Studies; Time Factors; Young Adult

2014
Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:1

    Topics: Adult; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Serine

2015
A Longitudinal (6-week) 3T (1)H-MRS Study on the Effects of Lithium Treatment on Anterior Cingulate Cortex Metabolites in Bipolar Depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:12

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Imaging, Three-Dimensional; Inositol; Lithium Compounds; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Protons; Statistics, Nonparametric; Young Adult

2015
Anterior cingulate Glutamate-Glutamine cycle metabolites are altered in euthymic bipolar I disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Analysis of Variance; Antidepressive Agents; Bipolar Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Mass Spectrometry; Middle Aged; Young Adult

2015
Relationship between body mass index and hippocampal glutamate/glutamine in bipolar disorder.
    The British journal of psychiatry : the journal of mental science, 2016, Volume: 208, Issue:2

    Topics: Adolescent; Adult; Bipolar Disorder; Body Mass Index; Body Weight; Case-Control Studies; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Young Adult

2016
Hippocampal neurochemical markers in bipolar disorder patients following the first-manic episode: A prospective 12-month proton magnetic resonance spectroscopy study.
    The Australian and New Zealand journal of psychiatry, 2017, Volume: 51, Issue:1

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Prospective Studies; Proton Magnetic Resonance Spectroscopy; Young Adult

2017
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders.
    Scientific reports, 2016, 11-21, Volume: 6

    Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Glutamine; Gray Matter; Humans; Inositol; Organ Specificity

2016
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania.
    Biological psychiatry, 2008, Oct-15, Volume: 64, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult

2008
Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex.
    Journal of child and adolescent psychopharmacology, 2008, Volume: 18, Issue:6

    Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Prefrontal Cortex

2008
Brain GABA levels in patients with bipolar disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Apr-30, Volume: 33, Issue:3

    Topics: Adult; Bipolar Disorder; Brain; Brain Mapping; Case-Control Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Spectrum Analysis

2009
Elevated metabolites within dorsolateral prefrontal cortex in rapid cycling bipolar disorder.
    Psychiatry research, 2009, Apr-30, Volume: 172, Issue:1

    Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex

2009
Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study.
    Psychiatry research, 2009, Jun-30, Volume: 172, Issue:3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Female; Frontal Lobe; Functional Laterality; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphorylcholine; Psychiatric Status Rating Scales; Severity of Illness Index

2009
Genetic polymorphisms (at codons 194 and 399) in the DNA repair gene XRCC1 and susceptibility to bipolar disorder.
    Psychiatry research, 2012, Jun-30, Volume: 198, Issue:1

    Topics: Bipolar Disorder; Case-Control Studies; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Linkage Disequilibrium; Male; Polymorphism, Genetic; Tryptophan; X-ray Repair Cross Complementing Protein 1

2012
Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex.
    Psychopharmacology, 2003, Volume: 168, Issue:3

    Topics: Acute Disease; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Receptors, Glutamate

2003
Exclusion of non-synonymous SNPs and a polyglutamine tract in SMRT/N-CoR2 as common deleterious mutation for bipolar disorder in the Sagnenay-Lac-St-Jean population.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2005, Apr-05, Volume: 134B, Issue:1

    Topics: Alleles; Bipolar Disorder; DNA-Binding Proteins; Gene Frequency; Genotype; Glutamine; Haplotypes; Humans; Mutation; Nuclear Receptor Co-Repressor 2; Peptides; Phenotype; Polymorphism, Single Nucleotide; Quebec; Repressor Proteins; Trinucleotide Repeats

2005
Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study.
    The American journal of psychiatry, 2006, Volume: 163, Issue:2

    Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Chemistry; Child; Comorbidity; Creatine; Dopamine; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Phosphocreatine; Protons; Serotonin; Tissue Distribution

2006
Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex.
    Journal of affective disorders, 2007, Volume: 99, Issue:1-3

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Comorbidity; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Risperidone

2007
Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects.
    Biological psychiatry, 2007, Mar-15, Volume: 61, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Occipital Lobe; Reference Values

2007
Glutamine and glutamate levels in children and adolescents with bipolar disorder: a 4.0-T proton magnetic resonance spectroscopy study of the anterior cingulate cortex.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2007, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Bipolar Disorder; Child; Child, Preschool; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neuroglia; Occipital Lobe; Protons; Psychotropic Drugs

2007
Metabolic alterations in medication-free patients with bipolar disorder: a 3T CSF-corrected magnetic resonance spectroscopic imaging study.
    Psychiatry research, 2008, Feb-28, Volume: 162, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain; Case-Control Studies; Caudate Nucleus; Corpus Striatum; Creatine; Cross-Sectional Studies; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values

2008
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder.
    Molecular psychiatry, 2009, Volume: 14, Issue:3

    Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Metabolomics; Middle Aged; Prefrontal Cortex; Rats; Rats, Inbred WKY; Reference Values

2009
Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders.
    Molecular psychiatry, 2009, Volume: 14, Issue:6

    Topics: Amino Acid Substitution; Arginine; Bipolar Disorder; Case-Control Studies; Chromosomes, Human, Pair 12; Depressive Disorder; Gene Frequency; Genes, Dominant; Genetic Predisposition to Disease; Glutamine; Haplotypes; Heterozygote; Homozygote; Humans; Linkage Disequilibrium; Microsatellite Repeats; Receptors, Purinergic P2; Receptors, Purinergic P2X7

2009
L-Glutamine and mania.
    The American journal of psychiatry, 1984, Volume: 141, Issue:10

    Topics: Bipolar Disorder; Food, Formulated; Glutamine; Humans; Male

1984
Analysis of polyglutamine-coding repeats in the TATA-binding protein in different human populations and in patients with schizophrenia and bipolar affective disorder.
    American journal of medical genetics, 1996, Sep-20, Volume: 67, Issue:5

    Topics: Africa; Bipolar Disorder; Cerebellar Ataxia; DNA-Binding Proteins; England; Ethnicity; Glutamine; Humans; Huntington Disease; India; Muscular Atrophy, Spinal; Peptides; Polymorphism, Genetic; Racial Groups; Schizophrenia; TATA-Box Binding Protein; Transcription Factors; Trinucleotide Repeats

1996
Increased cerebrospinal fluid glutamine levels in depressed patients.
    Biological psychiatry, 2000, Apr-01, Volume: 47, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Bipolar Disorder; Case-Control Studies; Creatine; Depressive Disorder; Female; Glutamine; Humans; Hydroxybutyrates; Magnesium; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sex Factors

2000
Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:5

    Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Child; Choline; Creatine; Energy Metabolism; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Reference Values; Temporal Lobe

2000