glutamine has been researched along with Benign Neoplasms in 485 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (8.66) | 18.7374 |
1990's | 24 (4.95) | 18.2507 |
2000's | 48 (9.90) | 29.6817 |
2010's | 238 (49.07) | 24.3611 |
2020's | 133 (27.42) | 2.80 |
Authors | Studies |
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Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
Aguilar, JMH; Alt, J; Dash, RP; Gori, SS; Lemberg, KM; Majer, P; Pal, A; Rais, R; Slusher, BS; Sun, Q; Tenora, L; Veeravalli, V; Wu, Y | 1 |
Badolati, N; Crescenzi, E; Leonardi, A; Mellone, S; Pacifico, F; Stornaiuolo, M | 1 |
Du, J; Hu, W; Huang, Z; Li, Y; Tong, X; Wang, X; Wang, Y; Xia, J; Zhou, Y | 1 |
Chen, Z; DiGiovanni, J; Wilder, CS | 1 |
Brunner, JS; Finley, LWS | 1 |
Deng, M; Du, K; Guo, R; Li, S; Lin, W; Lu, L; Mei, J; Wei, W; Zou, J | 1 |
Cai, X; Cimino, FV; King, B; Pavlova, NN; Schwörer, S; Sizemore, GM; Thompson, CB | 1 |
Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
Kraft, R; Krumbholz, P; Liebing, AD; Rabe, P; Stäubert, C | 1 |
Cabañas-Alite, L; García-Gozalbo, B | 1 |
Arenholz, E; Cerione, RA; Finke, A; Huang, Q; Katt, WP; Kriksunov, I; McDermott, LA; Milano, SK; Nguyen, TT; Ramachandran, S; Schuller, DJ; Sukumar, N; Szebenyi, DM | 1 |
Ding, M; Dong, R; Fares, HM; Li, X; Lyu, X; Mi, S; Sun, L; Wang, Y; Xu, X; Yuan, S | 1 |
Guo, H; Honda, Y; Matsui, M; Miura, Y; Nishiyama, N; Nomoto, T; Takemoto, H; Taniwaki, K | 1 |
Li, N; Lu, F; Pan, W; Tang, B; Wang, M | 1 |
Agnihotri, N; Kumar, S; Sharma, S | 1 |
Huang, C; Li, G; Li, Y; Suo, M; Tang, BZ; Xia, L; Xu, Y; Zhang, T; Zhu, D | 1 |
Cao, Y; Liao, W; Liu, N; Shi, F; Yang, L | 1 |
Audrito, V; Centonze, G; Coco, M; Cucinelli, S; Dalmasso, A; Defilippi, P; La Vecchia, S; Natalini, D; Orso, F; Paradzik, M; Quirico, L; Riganti, C; Taverna, D | 1 |
Joo, CG; Kang, J; Kim, TI; Seo, Y | 1 |
Le, A; Quinones, A; Zhang, C | 1 |
Madrigal Perez, LA; Nava, GM | 1 |
Bissonnette, MB; Chen, D; Chen, J; DeBerardinis, RJ; Elf, SE; Fan, H; Faubert, B; Gao, X; He, YY; Qu, CK; Tu, J; Wang, M; Wu, R; Zhang, FQ; Zhang, R; Zheng, H | 1 |
Hori, N; Kawamura, T; Takakura, Y; Takano, H; Takehora, Y; Yamaguchi, N | 1 |
Wu, Y; Zhu, L; Zhu, X | 1 |
Cai, Q; Chen, N; Dai, H; Di, C; Feng, J; Feng, R; Gou, X; Huang, J; Huang, M; Li, J; Li, Y; Liang, Z; Liu, J; Liu, S; Liu, X; Liu, Z; Lu, Y; Ma, L; Pan, J; Ruan, P; Su, S; Wang, J; Xia, Q; Ye, Y; Yu, S; Zhang, G; Zhao, Q; Zhou, B | 1 |
Chakravarti, A; Cheng, C; Cheng, X; Duan, W; Geng, F; Guo, D; Horbinski, C; Li, Z; Mo, X; Wang, H; Zhao, Y; Zhong, Y | 1 |
Briot, C; Freidman, NJ; Ryan, RM | 1 |
Aburatani, H; Candeias, MM; Ishiguro, K; Ishikawa, T; Kato, M; Lafontaine, DLJ; Matsumura, Y; Nishida, M; Okamoto, A; Osawa, T; Pan, M; Proud, CG; Sakai, J; Soga, T; Sugaya, M; Suzuki, T; Zhang, HF; Zorbas, C | 1 |
Crescenzi, E; D'Incalci, M; Leonardi, A; Mellone, S; Pacifico, F; Stornaiuolo, M | 1 |
Chen, B; Liu, W; Tang, BZ; Wang, D; Wang, L; Wen, H; Xiao, P; Xie, W | 1 |
Chen, Y; Li, D; Li, P; Liang, Y; Liang, Z; Ma, G; Niu, H; Wang, L; Zeng, M; Zhang, Z | 1 |
Estok, TM; Wild, R; Yokoyama, Y | 1 |
Albertini, E; Damisch, E; Fiegl, H; Guerrero-Navarro, L; Holzknecht, M; Jansen-Duerr, P; Parson, W; Petit, M; Schmitt, F; Simonini, A; Weiss, A | 1 |
Dasgupta, S; Kalhotra, P; Novickis, AT; Sawant Dessai, A | 1 |
DeBerardinis, RJ; Do, D; Faubert, B; Gu, W; Kaushik, AK; Ko, B; LaVigne, CA; Martin-Sandoval, MS; Mathews, TP; Mishra, P; Morrison, SJ; Pachnis, P; Ramesh, V; Rao, AD; Rogers, TJ; Shelton, S; Solmonson, A; Sudderth, J; Tasdogan, A; Ubellacker, JM; Wu, Z; Yang, C; Zacharias, LG; Zhao, Z | 1 |
Calder, PC; Douglas, C; McCullough, FS; Miller, LJ; Stanworth, SJ | 1 |
Chen, M; Li, M; Lin, Z; Qin, X; Shi, J; Xu, F; Ye, J; Zheng, Z | 1 |
Imai, T; Matsuhashi, N; Okumura, N; Sato, Y; Shimokawa, T; Takahashi, T; Tanaka, Y; Yoshida, K | 1 |
Archilla, I; Benítez-Ribas, D; Camps, J; Cascante, M; Castells, A; Cuatrecasas, M; de Herreros, MG; Foguet, C; Maurel, J; Oliveres, H; Pedrosa, L; Postigo, A; Prat, A; Rodríguez, A; Thomson, TM | 1 |
Bai, C; Fang, M; He, Z; Huang, L; Jiang, Q; Jin, C; Lu, S; Qin, F; Sun, J; Wang, Y; Xu, X; Yan, Q; Zhang, T; Zhang, Y; Zhao, C | 1 |
Foster, DA; Frias, MA; Hatipoglu, A; Levy, T; Menon, D | 1 |
Ackermann, T; Allega, MF; Bird, TG; Blancke, G; Bloom, A; Blyth, K; Deshmukh, R; Drake, TM; Huang, DT; Jans, M; Lewis, DY; May, S; Müller, M; Murphy, DJ; Nakasone, MA; Nixon, C; Oetjen, J; Sansom, OJ; Sumpton, D; Tan, EH; Tardito, S; Vande Voorde, J; Vereecke, L; Villar, VH | 1 |
Celiku, O; Friedenberg, MD; Gilbert, MR; Larion, M; Lita, A | 1 |
Aguilar, JMH; Alt, J; Arwood, ML; Dash, RP; Lam, J; Lemberg, KM; Leone, RD; Majer, P; Pal, A; Pandey, R; Peters, DE; Powell, JD; Rais, R; Seiwert, T; Slusher, BS; Tallon, C; Tenora, L; Thomas, AG; Wu, Y; Zhao, L | 1 |
Baek, S; Jang, Y; Joo, S; Kang, J; Kwon, TK; Seo, DS | 1 |
Bajgain, P; Cuttitta, F; Dimitrov, DS; Dunleavey, JM; Emenaker, NJ; Feng, Y; Hilton, MB; Hsu, KS; Koogle, R; Lutz, EM; Morris, K; Rose, J; Saha, S; Seaman, S; St Croix, B; Szot, C; Tessarollo, L; Tomassoni-Ardori, F; Yang, L; Zhang, XM; Zhu, Z; Zudaire, E | 1 |
Barnes, S; Benavides, GA; Darley-Usmar, VM; Johnson, MS; Tian, R; Xing, D | 1 |
Chomiczewska, A; Hallmann, A; Lipiński, M; Michnowska, A; Smolarz, K | 1 |
Li, H; Mao, H; Sun, B; Wang, J; Wen, Y; Yu, Y | 1 |
Chuang, YC; Kao, TW; Kuo, CC; Lee, HL; Shen, YA | 1 |
Peng-Fei, S; Xiao-Xia, Y; Xiao-Yan, W; Xiu-Li, G; Zong-Xue, Z | 1 |
Chae, HS; Hong, ST | 1 |
Bian, J; Chen, R; Gong, G; Guo, Z; Huang, H; Li, X; Li, Z; Lu, Y; Wang, D | 1 |
Amiri Khosroshahi, R; Imani, H; Mohammadi, H; Rashidi, A; Talebi, S; Travica, N; Zeraattalab-Motlagh, S | 1 |
Crescenzi, E; Leonardi, A; Pacifico, F | 1 |
Amere Subbarao, S; Dharaskar, SP | 1 |
Antsaklis, P; Chionis, A; Daskalakis, G; Fasoulakis, Z; Katrachouras, A; Konis, K; Kontomanolis, EN; Koutras, A; Nikolettos, K; Ntounis, T; Pagkalos, A; Palios, VC; Perros, P; Prokopakis, I; Samara, AA; Sapantzoglou, I; Sotiriou, S; Symeonidis, P; Theodora, M; Valsamaki, A | 1 |
de Menêses, AG; Dos Reis, PED; E Vasconcelos, SCCM; Ferreira, EB; Guerra, ENS | 1 |
Byun, JK; Choi, YK; Jin, J; Park, KG | 1 |
Cheng, Z; Han, T; Hu, Q; Li, D; Li, Y; Wang, K; Yao, L; Yuan, Y | 1 |
Li, N; Liu, X; Pan, W; Shi, M; Tang, B; Wang, K; Wang, M; Wei, R; Zhang, H; Zhang, X | 1 |
Aceto, G; Adams, BN; Avizonis, DZ; Chen, SY; Ching, K; Choiniere, L; Foulkes, WD; Fu, L; Fu, Z; Ho, R; Huang, S; Huntsman, DG; Klein Geltink, RI; Li, E; Monast, A; Morin, GB; Negri, GL; Ong, D; Park, M; Pavlakis, K; Pilon, V; Pirrotte, P; Steinberger, J; Ta, M; Trent, J; Wang, Y; Weissman, BE; Zhu, X | 1 |
De, K; Mukhopadhyay, S; Prasad, P; Roy, SS; Sinha, S | 1 |
Dai, L; Du, H; Geng, M; Gong, L; Li, X; Meng, S; Yang, H; Yuan, Z; Zhao, P; Zhao, Y; Zheng, X | 1 |
Bader, JE; Chi, C; Fisher, EL; Hathaway, ES; Karijolich, J; Landis, MD; Madden, MZ; Muka, JE; Needle, GA; O'Neil, RT; Patterson, AR; Philip, M; Rathmell, JC; Reinfeld, BI; Wolf, MM; Ye, X | 1 |
Chapman, NM; Chi, H; Dhungana, Y; Du, X; Guo, C; Guy, C; Lim, SA; Palacios, G; Rankin, S; Saravia, J; Shi, H; Sun, X; Sun, Y; You, Z; Yuan, S | 1 |
Balieiro, JCC; Bonder, BSA; Brunetto, MA; de-Oliveira, CM; Fantoni, DT; Gonçales, LA; Massoco, CO; Nagashima, JK; Pfrimer, K; Pontieri, CFF; Porsani, MYH; Teixeira, FA | 1 |
Ai, C; Guo, L; Li, J; Meng, D; Shang, M; Shi, D; Sun, X; Wang, X; Xiao, S; Zhao, Y | 1 |
Byrne, HJ; Cahill, P; Howe, O; Mirveis, Z; Patil, N | 1 |
Gu, Z; Han, M; Han, Y; Hu, C; Li, Z; Wang, L | 1 |
Arpaci, T; Semerci, R; Yılmaz, P | 1 |
Araújo Júnior, RF; Araújo, AA; Clebis, NK; Fracaro, L; Lacchini, S; Lima, KRA; Lima, MFO; Lins, LAA; Lopes, MLDS; Perles, JVCM; Purificação, NRCD; Souza, SRG; Zanoni, JN | 1 |
Alt, J; Gori, S; Lam, J; Majer, P; Mettu, VS; Novotná, K; Paule, J; Prchalová, E; Rais, R; Slusher, BS; Šnajdr, I; Tenora, L; Tsukamoto, T; Veeravalli, V; Wu, Y | 1 |
Hoang, G; Le, A; Udupa, S | 1 |
Al-Nawas, B; Bache, M; Bull, F; Eckert, AW; Grosse, I; Güttler, A; Kappler, M; Kaune, T; Kotrba, J; Krohn, K; Pabst, U; Porsch, M; Riemann, A; Rot, S; Schubert, J; Seliger, B; Taubert, H; Thews, O; Vordermark, D; Weinholdt, C; Wickenhauser, C | 1 |
Curtin, NJ; Unterlass, JE | 1 |
Lulli, M; Nencioni, D; Papucci, L; Schiavone, N | 1 |
Boroughs, L; Britt, R; Byers, LA; Cai, L; Chen, D; Chen, J; Chen, PH; DeBerardinis, RJ; Faubert, B; Girard, L; Heymach, JV; Huffman, K; Kim, HS; Kim, J; Ko, B; McMillan, EA; Minna, JD; Peyton, M; Sekine, I; Shames, DS; Shields, MD; Sudderth, J; Timmons, B; Weber, S; White, MA; Xiao, G; Yang, C; Yao, B | 1 |
Campos-Sandoval, JA; Márquez, J; Matés, JM; Santos-Jiménez, JL | 1 |
Bordon, Y | 1 |
Brusa, D; Corbet, C; Feron, O; Gallez, B; Joudiou, N; Schoonjans, CA | 1 |
Aranda, E; López-Sánchez, LM; Rodríguez-Ariza, A | 1 |
Dang, CV; Stine, ZE | 2 |
Bang, S; Choi, J; Han, JM; Heo, Y; Hwang, GS; Kang, J; Kang, JS; Kim, JK; Kim, K; Kim, YH; Lee, CW; Lee, HS; Lee, J; Lee, MY; Nam, M; Park, SJ; Yeo, JH; Yoo, HC | 1 |
Huang, H; Li, S; Liu, Y; Luo, Z; Ma, W; Pardeshi, A; Sun, J; Wan, Z; Xu, J; Zhang, Z | 1 |
Bai, C; Chen, C; Chu, Q; Cui, Y; Li, B; Liu, M; Ruan, Y; Wang, Y; Yang, C; Ying, G | 1 |
Diehl, JA; Qie, S | 1 |
DeBerardinis, RJ | 1 |
Chen, CJ; Chen, WY; Ko, CC; Li, JR; Liao, SL; Lin, SY; Wang, JD; Wang, YY; Wu, CC | 1 |
Bamba, T; Izumi, Y; Kodama, M; Matsumoto, M; Nakayama, KI; Oshikawa, K; Shimizu, H; Takahashi, M; Tateishi, C; Tomonaga, T; Yoshioka, S | 1 |
Chevet, E; Eldering, E; Favaro, F; Iurlaro, R; Lucendo, E; Majem, B; Marchetti, S; Muñoz-Pinedo, C; Nadal, E; Püschel, F; Redondo-Pedraza, J; Ricci, JE | 1 |
Chiellini, G | 1 |
Contreras-Paredes, A; Langley, E; Lizano, M; Martínez-Ramírez, I; Muñoz-Bello, JO; Olmedo-Nieva, L; Ortiz-Pedraza, Y | 1 |
Chen, J; Chen, X; Gao, W; Hao, B; Huang, M; Huang, W; Li, K; Liu, J; Liu, Q; Liu, R; Shao, Y; Wang, J; Wang, Q; Wei, Z; Xu, P; Xu, Y; Ye, S; Zeng, S; Zhang, H; Zhang, Q; Zhong, Z | 1 |
Dey, S; Ghosh, P; Vidal, C; Zhang, L | 1 |
Kery, M; Papandreou, I | 1 |
Cocetta, V; Montopoli, M; Ragazzi, E | 1 |
Anderson, PM; Lalla, RV | 1 |
Huo, YY; Li, NY; Liu, M; Pan, YH; Sun, YP; Xu, W | 1 |
Campos-Sandoval, JA; de Los Santos-Jiménez, J; Márquez, J; Matés, JM | 1 |
Bridges, EM; Cunningham, C; Ellis, M; Fan, SJ; Goberdhan, DC; Hamdy, FC; Harris, AL; Johnson, E; Khalid Alham, N; Kroeger, B; Marie, PP; Mason, JD; McCormick, K; Mendes, CC; Morris, JF; Sheldon, H; Stefana, MI; Wainwright, SM; Wilson, C; Zois, CE | 1 |
Théry, C; van Niel, G | 1 |
Endo, H; Inagaki, Y; Owada, S; Shida, Y; Tatemichi, M | 1 |
Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; 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Eremin, O; Gough, DB; Heys, SD; Khan, L | 1 |
Klimberg, VS; McClellan, JL | 1 |
Breitkreutz, R; Drings, P; Dröge, W; Hack, V; Holm, E; Kinscherf, R; Schmid, D; Stahl-Henning, C; Taut, F | 1 |
Dröge, W; Holm, E | 1 |
Boschek, CB; Eigenbrodt, E; Mazurek, S | 1 |
Bunnak, A; Chockvivatanavanit, S; Chuntrasakul, C; Leowattana, W; Sarasombath, S; Siltharm, S; Sittapairochana, C | 1 |
Barber, MD; Delmore, G; Fearon, KC; Loprinzi, CL | 1 |
Brown, T; Hidalgo, M; Kuhn, JG; MacGovren, JP; Rodriguez, G; Rowinsky, EK; Von Hoff, DD; Weiss, G | 1 |
Boucher, J; Corey, B; Savarese, D | 1 |
de Blaauw, I; Deutz, NE; von Meyenfeldt, MF | 1 |
Miller, AL | 1 |
Field, CJ; Johnson, I; Pratt, VC | 1 |
Brand, O; Göbel, U; Klowik, M; Köhler, H; Schroten, H | 1 |
Doi, H; Komatsu, H; Nishihira, T; Satomi, S | 1 |
Baker, SD; Bowling, MK; Carducci, MA; Donehower, RC; Figg, WD; Gilbert, J; Grochow, L; Zabelina, Y | 1 |
Dechelotte, P; Nitenberg, G | 1 |
Karinch, AM; Lin, CM; Pan, M; Souba, WW; Strange, R | 1 |
Medina, MA | 1 |
Ziegler, TR | 1 |
Bowling, MK; Carducci, MA; Chen, TL; Donehower, RC; Eisenberger, MA; Gilbert, J; Grochow, LB; Noe, D; Sinibaldi, V; Zabelina, Y | 1 |
Eigenbrodt, E; Jansen-Dürr, P; Mazurek, S; Zwerschke, W | 1 |
Capria, S; Grieco, G; Iori, AP; Muscaritoli, M; Rossi Fanelli, F | 1 |
Asenjo, M; Márquez, J; Matés, JM; Núñez de Castro, I; Pérez-Gómez, C | 1 |
Abumrad, NN; Barber, A; D'Olimpio, JT; Hourihane, A; May, PE | 1 |
Hasegawa, K; Hiramatsu, Y; Hongo, A; Kodama, J; Kudo, T; Kuramoto, H; Masuyama, H; Mizutani, Y; Nagao, S; Okuda, H; Yoshinouchi, M | 1 |
Borella, LD; Camitta, BM; Holcenberg, JS; Ring, BJ | 1 |
Christie, TR; Clarke, LP; Gelbard, AS; Laughlin, JS | 1 |
Márquez, J; Medina, MA; Núñez de Castro, I; Rodríguez Quesada, A; Sánchez-Jiménez, F | 1 |
Newsholme, EA | 1 |
Medina, MA; Núñez de Castro, I | 1 |
Ollenschläger, G; Roth, E; Simmel, A | 1 |
McKeehan, WL | 1 |
Ardawi, MS; Crabtree, B; Newsholme, EA | 1 |
Hersh, EM | 1 |
Carter, SK; Cooney, DA; Livingston, RB; Venditti, JM | 1 |
Chakraborty, P; Shrivastava, GC | 1 |
Shrivastava, GC | 1 |
van Os, FH | 1 |
Tsuiki, S | 1 |
Balis, ME; Krakoff, IH; Miller, HK; Salser, JS | 1 |
Björnesjö, KB | 1 |
Theimer, W | 1 |
Balis, ME; Miller, HK; Salser, JS | 1 |
214 review(s) available for glutamine and Benign Neoplasms
Article | Year |
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6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
Pharmacologic approaches to amino acid depletion for cancer therapy.
Topics: Amino Acids; Arginine; Glutamine; Humans; Neoplasms; Oxidation-Reduction | 2022 |
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
A Narrative Review about Nutritional Management and Prevention of Oral Mucositis in Haematology and Oncology Cancer Patients Undergoing Antineoplastic Treatments.
Topics: Adult; Antineoplastic Agents; Child; Dietary Supplements; Female; Glutamine; Honey; Humans; Male; Neoplasms; Stomatitis; Treatment Outcome; Vitamins | 2021 |
Autophagy in cancer: The cornerstone during glutamine deprivation.
Topics: Autophagy; Glutamine; Homeostasis; Humans; Neoplasms; Oxidation-Reduction | 2022 |
Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysis.
Topics: Cell Transformation, Neoplastic; Citric Acid Cycle; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Tumor Microenvironment | 2022 |
Oncogenic viral infection and amino acid metabolism in cancer progression: Molecular insights and clinical implications.
Topics: Amino Acids; Glutamine; Humans; Neoplasms; Oncogenic Viruses | 2022 |
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression.
Topics: Cell Adhesion; Cell Movement; Glucose; Glutamine; Humans; MicroRNAs; Neoplasms | 2022 |
Metabolic reservoir cycles in cancer.
Topics: Glutamic Acid; Glutamine; Glycogen; Humans; Lactic Acid; Neoplasms; Triglycerides | 2022 |
Metabolic profile of the Warburg effect as a tool for molecular prognosis and diagnosis of cancer.
Topics: Amino Acids, Branched-Chain; Glucose; Glutamine; Humans; Metabolome; Neoplasms; Proline | 2022 |
Effects of Glucose Metabolism, Lipid Metabolism, and Glutamine Metabolism on Tumor Microenvironment and Clinical Implications.
Topics: Glucose; Glutamine; Humans; Lipid Metabolism; Myeloid-Derived Suppressor Cells; Neoplasms; Tumor Microenvironment | 2022 |
Reprogramming of glutamine metabolism and its impact on immune response in the tumor microenvironment.
Topics: Glutamine; Humans; Immunity; Immunotherapy; Neoplasms; Tumor Microenvironment | 2022 |
Regulation of tumor metabolism by post translational modifications on metabolic enzymes.
Topics: Citric Acid Cycle; Glutamine; Glycolysis; Humans; Neoplasms; Protein Processing, Post-Translational; Tumor Microenvironment | 2023 |
Impact of enteral immunonutrition on infectious complications and immune and inflammatory markers in cancer patients undergoing chemotherapy: A systematic review of randomised controlled trials.
Topics: Adult; Arginine; Biomarkers; Fatty Acids, Omega-3; Glutamine; Humans; Malnutrition; Neoplasms; Nucleotides; Randomized Controlled Trials as Topic; Tumor Necrosis Factor-alpha; Vitamin A; Vitamins | 2022 |
Hormone-Glutamine Metabolism: A Critical Regulatory Axis in Endocrine-Related Cancers.
Topics: Endocrine Gland Neoplasms; Endocrine System; Glutamine; Humans; Insulin; Neoplasms; Thyroid Hormones | 2022 |
Therapeutic Targeting of Glutaminolysis as a Novel Strategy to Combat Cancer Stem Cells.
Topics: Glucose; Glutamic Acid; Glutaminase; Glutamine; Humans; Neoplasms; Neoplastic Stem Cells | 2022 |
Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity.
Topics: Amino Acids; Cell Transformation, Neoplastic; Drug Resistance, Multiple; Glutamine; Humans; Neoplasms | 2023 |
Overview of Cancer Metabolism and Signaling Transduction.
Topics: Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; Neoplasms; Signal Transduction | 2022 |
An updated patent review of glutaminase inhibitors (2019-2022).
Topics: Enzyme Inhibitors; Glutaminase; Glutamine; Humans; Neoplasms; Patents as Topic | 2023 |
Nutritional interventions for the prevention and treatment of cancer therapy-induced oral mucositis: an umbrella review of systematic reviews and meta-analysis.
Topics: Glutamine; Humans; Meta-Analysis as Topic; Neoplasms; Propolis; Stomatitis; Systematic Reviews as Topic | 2023 |
Glutamine Metabolism in Cancer Stem Cells: A Complex Liaison in the Tumor Microenvironment.
Topics: Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Neoplastic Stem Cells; Tumor Microenvironment | 2023 |
Ovarian Cancer and Glutamine Metabolism.
Topics: Energy Metabolism; Female; Glutamine; Glycolysis; Humans; Neoplasms; Ovarian Neoplasms | 2023 |
Effects of oral supplementation to manage radiation dermatitis in cancer patients: a systematic review.
Topics: Dietary Supplements; Glutamine; Humans; Neoplasms; Radiodermatitis | 2023 |
Targeting glutamine metabolism as a therapeutic strategy for cancer.
Topics: Amino Acids; Citric Acid Cycle; Glutamine; Humans; Neoplasms; Oxidation-Reduction; Tumor Microenvironment | 2023 |
Amino acid metabolism regulated by lncRNAs: the propellant behind cancer metabolic reprogramming.
Topics: Epigenesis, Genetic; Glutamine; Humans; Neoplasms; Protein Processing, Post-Translational; RNA, Long Noncoding | 2023 |
Monitoring and modelling the glutamine metabolic pathway: a review and future perspectives.
Topics: Energy Metabolism; Glutamine; Humans; Metabolic Networks and Pathways; Metabolomics; Neoplasms | 2023 |
Warburg and Krebs and related effects in cancer.
Topics: Animals; Glucose; Glutamine; Humans; Neoplasms; Phenotype; Tumor Microenvironment | 2019 |
Zeta-crystallin: a moonlighting player in cancer.
Topics: Acidosis; Ammonia; Animals; Apoptosis; Glutamine; Humans; Neoplasms; Oxidative Stress; Protein Binding; RNA, Messenger; zeta-Crystallins | 2020 |
Dysregulation of glutaminase and glutamine synthetase in cancer.
Topics: Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Glycolysis; Humans; Neoplasms; Tumor Microenvironment | 2019 |
Nitric oxide and tumor metabolic reprogramming.
Topics: Cell Proliferation; Energy Metabolism; Glucose; Glutamine; Humans; Mitochondria; Neoplasms; Nitric Oxide; Signal Transduction; Tumor Microenvironment | 2020 |
Cyclin D degradation by E3 ligases in cancer progression and treatment.
Topics: Cyclin D; Drug Resistance, Neoplasm; F-Box Proteins; Glutamine; Humans; Molecular Targeted Therapy; Neoplasms; Ubiquitin Thiolesterase; Ubiquitin-Protein Ligases; Ubiquitination | 2020 |
Non-Coding RNAs as Key Regulators of Glutaminolysis in Cancer.
Topics: Animals; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Metabolic Networks and Pathways; MicroRNAs; Molecular Targeted Therapy; Neoplasms; RNA Interference; RNA, Circular; RNA, Untranslated | 2020 |
Mitochondria Targeting as an Effective Strategy for Cancer Therapy.
Topics: Antimetabolites, Antineoplastic; Citric Acid Cycle; Drug Resistance, Neoplasm; Dynamins; Energy Metabolism; Glutamine; Glycolysis; GTP Phosphohydrolases; Heme; Humans; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Oxidative Phosphorylation; Oxidative Stress; Tumor Microenvironment | 2020 |
Emerging strategies to target cancer metabolism and improve radiation therapy outcomes.
Topics: Adaptation, Physiological; Animals; Ataxia Telangiectasia Mutated Proteins; DNA; DNA Damage; DNA Repair; Genomic Instability; Glutamine; Glutarates; Glutathione; Humans; Immunotherapy; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lipid Peroxidation; Mice; Neoplasms; Nucleotides; Oxygen Consumption; Phospholipids; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Stress, Physiological; Treatment Outcome; Tumor Microenvironment | 2020 |
Links between cancer metabolism and cisplatin resistance.
Topics: Amino Acids; Animals; Antineoplastic Agents; Cisplatin; Drug Resistance, Neoplasm; Glutamine; Glycolysis; Humans; Mitochondria; Neoplasms | 2020 |
Glutamine for Amelioration of Radiation and Chemotherapy Associated Mucositis during Cancer Therapy.
Topics: Antineoplastic Agents; Diet, High-Protein; Dietary Proteins; Dietary Sucrose; Dietary Supplements; Glutamine; Humans; Malnutrition; Mucositis; Mucous Membrane; Neoplasms; Radiotherapy; Trehalose; Wound Healing | 2020 |
Glutaminases regulate glutathione and oxidative stress in cancer.
Topics: Animals; Antineoplastic Agents; Antioxidants; Energy Metabolism; Enzyme Inhibitors; Glutamic Acid; Glutaminase; Glutamine; Glutathione; Humans; Mitochondria; Neoplasms; Oxidative Stress; Signal Transduction; Tumor Microenvironment | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Glutamine reliance in cell metabolism.
Topics: Animals; Cell Transformation, Neoplastic; Disease Susceptibility; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Metabolic Networks and Pathways; Metabolome; Metabolomics; Neoplasms; Oxidation-Reduction; Signal Transduction | 2020 |
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy.
Topics: Amino Acid Transport System y+; Antineoplastic Agents; Cystine; DNA Methylation; Ferroptosis; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glutathione; Histones; Humans; Molecular Targeted Therapy; Neoplasms; Piperazines; Signal Transduction; Sorafenib; Sulfasalazine | 2021 |
A second Warburg-like effect in cancer metabolism: The metabolic shift of glutamine-derived nitrogen: A shift in glutamine-derived nitrogen metabolism from glutaminolysis to de novo nucleotide biosynthesis contributes to malignant evolution of cancer.
Topics: Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides | 2020 |
Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function.
Topics: Amino Acids, Essential; Animal Proteins, Dietary; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus; Diet, Vegetarian; Fatty Acids; Functional Food; Glutamine; Humans; Metabolic Diseases; Neoplasms; Nutritive Value; Plant Proteins; Risk Factors; Whey Proteins | 2020 |
LKB1 deficiency-induced metabolic reprogramming in tumorigenesis and non-neoplastic diseases.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Apoptosis; Carcinogenesis; Energy Metabolism; Glucose; Glutamine; Humans; Lipid Metabolism; Lipids; Metabolic Engineering; Metabolic Networks and Pathways; Mutation; Neoplasms; Peutz-Jeghers Syndrome; Protein Serine-Threonine Kinases; Serine; Signal Transduction | 2021 |
Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance.
Topics: Amino Acids; Animals; Citric Acid Cycle; Dimerization; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glucose; Glutamine; Humans; Hypoxia; Lactic Acid; Mice; Mitochondria; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen; Phenotype; Reactive Oxygen Species; Tumor Microenvironment | 2020 |
The metabolism of cancer cells during metastasis.
Topics: Acetates; Adenosine Triphosphate; Animals; Cell Plasticity; Fatty Acids; Glutamine; Humans; Lactic Acid; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; Pyruvic Acid | 2021 |
The role of the glutamine transporter ASCT2 in antineoplastic therapy.
Topics: Amino Acid Transport System ASC; Animals; Antibodies, Monoclonal; Glutamine; Humans; Minor Histocompatibility Antigens; Neoplasms; Oxidative Stress | 2021 |
Host cell glutamine metabolism as a potential antiviral target.
Topics: Antiviral Agents; Cell Line, Tumor; Glutamine; Host-Pathogen Interactions; Humans; Metabolic Networks and Pathways; Neoplasms; Virulence; Virus Replication; Viruses | 2021 |
Effectiveness of glutamine in the management of oral mucositis in cancer patients: a meta-analysis of randomized controlled trials.
Topics: Glutamine; Humans; Neoplasms; Prospective Studies; Randomized Controlled Trials as Topic; Stomatitis | 2021 |
Role of Glutamine in the Management of Oral Mucositis in Patients with Cancer: A Meta-Analysis of Randomized Controlled Trials.
Topics: Databases, Factual; Glutamine; Humans; Neoplasms; Randomized Controlled Trials as Topic; Stomatitis | 2022 |
Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis.
Topics: Animals; Carcinogenesis; Citric Acid Cycle; Disease Progression; Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; L-Lactate Dehydrogenase; Neoplasms; Oxygen Consumption | 2021 |
The emerging regulatory roles of long non-coding RNAs implicated in cancer metabolism.
Topics: Animals; Glutamine; Glycolysis; Humans; Lipid Metabolism; Mitochondria; Neoplasms; RNA, Long Noncoding | 2021 |
Glutamine metabolism: from proliferating cells to cardiomyocytes.
Topics: Animals; Cell Differentiation; Cell Proliferation; Glutamine; Humans; Myoblasts, Cardiac; Myocytes, Cardiac; Neoplasms; Stem Cells; Tumor Microenvironment | 2021 |
Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Disease Models, Animal; Drug Resistance, Neoplasm; Glutaminase; Glutamine; Humans; Neoplasms; NF-E2-Related Factor 2; Oxidative Stress; Thiadiazoles; Tumor Escape; Tumor Microenvironment | 2021 |
Targeting GLS1 to cancer therapy through glutamine metabolism.
Topics: Apoptosis; Benzophenanthridines; Cell Proliferation; Diazooxonorleucine; Disease Progression; Drug Resistance, Neoplasm; Genes, myc; Glutaminase; Glutamine; Humans; MicroRNAs; Neoplasm Proteins; Neoplasms; NF-kappa B; Oxidation-Reduction; Phosphates; Prognosis; Retinoblastoma Protein; Sulfides; Thiadiazoles | 2021 |
Metabolomics-guided global pathway analysis reveals better insights into the metabolic alterations of breast cancer.
Topics: Glutamine; Metabolic Networks and Pathways; Metabolome; Metabolomics; Neoplasms; Oxidation-Reduction | 2021 |
Effect of glutamine metabolism on chemoresistance and its mechanism in tumors.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Glutamine; Glycolysis; Humans; Neoplasms; Oxidative Phosphorylation; Tumor Microenvironment | 2021 |
Glutamine Metabolism in Cancer: Understanding the Heterogeneity.
Topics: Glutaminase; Glutamine; Humans; Molecular Targeted Therapy; Neoplasms | 2017 |
Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine.
Topics: Animals; Cell Proliferation; Glutamine; Humans; Neoplasms | 2017 |
Therapeutic role of glutamine in management of radiation enteritis: a meta-analysis of 13 randomized controlled trials.
Topics: Case-Control Studies; Enteritis; Glutamine; Humans; Neoplasms; Odds Ratio; Publication Bias; Radiation Injuries; Radiotherapy; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome | 2017 |
Hopefully devoted to Q: targeting glutamine addiction in cancer.
Topics: Autophagy; Drug Discovery; Glutamine; Glycosylation; Humans; Metabolic Networks and Pathways; Neoplasms; TOR Serine-Threonine Kinases; Tumor Microenvironment | 2017 |
Nutrient acquisition strategies of mammalian cells.
Topics: Animals; Cell Proliferation; Cells; Endocytosis; Glucose; Glutamine; Intercellular Signaling Peptides and Proteins; Lysosomes; Neoplasms; Pinocytosis; Proteins; Tumor Microenvironment | 2017 |
From Prokaryotes to Cancer: Glutamine Flux in Multicellular Units.
Topics: Animals; Biofilms; Biological Transport; Glutamine; Humans; Neoplasms; Prokaryotic Cells; Subcellular Fractions | 2017 |
Drug-induced amino acid deprivation as strategy for cancer therapy.
Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparaginase; Glutamine; Humans; Neoplasms | 2017 |
Targeting Metabolism for Cancer Therapy.
Topics: Antimetabolites; Argininosuccinate Synthase; Carbohydrate Metabolism; Fatty Acids; Glutamine; Glycolysis; Humans; Isocitrate Dehydrogenase; Metabolic Engineering; NAD; Neoplasms | 2017 |
MYC and tumor metabolism: chicken and egg.
Topics: Animals; Apoptosis; Biogenic Polyamines; Forkhead Box Protein O1; Genes, myc; Glucose; Glutamine; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolic Networks and Pathways; Neoplasms; Nucleotides; Proto-Oncogene Proteins c-myc; Stress, Physiological | 2017 |
The diamond anniversary of tissue transglutaminase: a protein of many talents.
Topics: Amines; Animals; Disease Progression; Glutamine; GTP-Binding Proteins; Humans; Neoplasms; Transglutaminases | 2018 |
Impairing energy metabolism in solid tumors through agents targeting oncogenic signaling pathways.
Topics: Antineoplastic Agents; Carcinogens; Energy Metabolism; Glutamine; Glycolysis; Humans; Lipid Metabolism; Neoplasms; Signal Transduction | 2018 |
CNF1-like deamidase domains: common Lego bricks among cancer-promoting immunomodulatory bacterial virulence factors.
Topics: Amidohydrolases; Asparagine; Bacterial Toxins; Computational Biology; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Glutamine; Immunologic Factors; Neoplasms; rac1 GTP-Binding Protein; Virulence Factors | 2018 |
Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer.
Topics: Amino Acid Transport System y+; Antioxidants; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Homeostasis; Humans; Neoplasms; Nutrients; Oxidation-Reduction | 2018 |
Cancer stem cell metabolism: target for cancer therapy.
Topics: Glutamine; Glycolysis; Humans; Lipid Metabolism; Metabolic Networks and Pathways; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Oxidative Phosphorylation; Tumor Microenvironment | 2018 |
Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer.
Topics: Antineoplastic Agents; Drug Discovery; Glutamine; Glycolysis; Humans; Neoplasms | 2018 |
Cancer in the crosshairs: targeting cancer metabolism with hyperpolarized carbon-13 MRI technology.
Topics: Animals; Carbon Isotopes; Glutamine; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Neoplasms | 2019 |
Targeting cancer metabolism through synthetic lethality-based combinatorial treatment strategies.
Topics: Amino Acid Transport System ASC; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Glucose; Glucose Transport Proteins, Facilitative; Glutaminase; Glutamine; Humans; Lactic Acid; Minor Histocompatibility Antigens; Molecular Targeted Therapy; Monocarboxylic Acid Transporters; Neoplasms; Pyruvate Dehydrogenase Complex | 2018 |
We're Not "DON" Yet: Optimal Dosing and Prodrug Delivery of
Topics: Animals; Antimetabolites, Antineoplastic; Diazooxonorleucine; Glutamine; Humans; Molecular Structure; Nausea; Neoplasms; Prodrugs; Vomiting | 2018 |
Discovery and development of small molecule modulators targeting glutamine metabolism.
Topics: Animals; Antineoplastic Agents; Drug Discovery; Energy Metabolism; Glutamine; Humans; Neoplasms | 2019 |
Glutamine as an Essential Amino Acid for KRas-Driven Cancer Cells.
Topics: Amino Acids, Essential; Animals; Glutamine; Humans; Neoplasms; Proto-Oncogene Proteins p21(ras); TOR Serine-Threonine Kinases | 2019 |
Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis.
Topics: ATP Citrate (pro-S)-Lyase; Disease Progression; Energy Metabolism; Fatty Acids; Glucose; Glucose-6-Phosphate Isomerase; Glutaminase; Glutamine; Humans; Isocitrate Dehydrogenase; Neoplasm Metastasis; Neoplasms | 2019 |
Therapeutic targeting of glutaminolysis as an essential strategy to combat cancer.
Topics: Antineoplastic Agents; Cell Proliferation; Cellular Reprogramming; Enzyme Inhibitors; Glutaminase; Glutamine; Humans; Neoplasms | 2020 |
Molecular mechanisms of ferroptosis and its role in cancer therapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cysteine; Endoplasmic Reticulum Stress; Fatty Acids, Unsaturated; Ferroptosis; Glutamine; Humans; Iron; Lipid Peroxidation; Lysosomes; Mitochondria; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Signal Transduction | 2019 |
Systematic review of natural and miscellaneous agents for the management of oral mucositis in cancer patients and clinical practice guidelines-part 1: vitamins, minerals, and nutritional supplements.
Topics: Dietary Supplements; Glutamine; Head and Neck Neoplasms; Humans; Minerals; Mucositis; Neoplasms; Stomatitis; Vitamins | 2019 |
Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines.
Topics: Butyric Acid; Chemoradiotherapy; Fibroblast Growth Factor 7; Glutamine; Humans; Hyperbaric Oxygenation; Mucositis; Neoplasms; Practice Guidelines as Topic; Proctitis; Stomatitis | 2019 |
Integrating dietary supplements into cancer care.
Topics: Camellia sinensis; Curcumin; Dietary Supplements; Fish Oils; Glutamine; Grifola; Humans; Integrative Medicine; Neoplasms; Probiotics; Vitamin D | 2013 |
miRNAs link metabolic reprogramming to oncogenesis.
Topics: Animals; Carcinogenesis; Cell Proliferation; Citric Acid Cycle; Energy Metabolism; Glutamine; Glycolysis; Humans; Lipogenesis; MicroRNAs; Neoplasm Metastasis; Neoplasms; Signal Transduction | 2013 |
Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance.
Topics: Absorption; Animals; Cell Enlargement; Cell Proliferation; Citric Acid Cycle; Drug Resistance, Neoplasm; Fatty Acids; Glucose; Glutamine; Glycolysis; Humans; Lactates; Neoplasms; Signal Transduction; Treatment Outcome | 2013 |
A systems biology road map for the discovery of drugs targeting cancer cell metabolism.
Topics: Drug Discovery; Drug Resistance, Neoplasm; Genomic Instability; Glucose; Glutamine; Humans; Neoplasms; Signal Transduction; Systems Biology | 2014 |
Glutamine, glucose and other fuels for cancer.
Topics: Ammonia; Animals; Citric Acid Cycle; Glucose; Glutaminase; Glutamine; Glycolysis; Humans; Neoplasms; Oxidative Phosphorylation; Retinoblastoma Protein | 2014 |
Glutamine and cancer: cell biology, physiology, and clinical opportunities.
Topics: Animals; Biomarkers, Tumor; Energy Metabolism; Glutamine; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Neoplasms; Organ Specificity | 2013 |
Coordination of nutrient availability and utilization by MAX- and MLX-centered transcription networks.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Food; G1 Phase; Gene Regulatory Networks; Genes, myc; Glucose; Glutamine; Humans; Neoplasms; Tumor Suppressor Proteins | 2013 |
Therapeutic strategies impacting cancer cell glutamine metabolism.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Glutaminase; Glutamine; Humans; Models, Molecular; Molecular Targeted Therapy; Neoplasms; Signal Transduction | 2013 |
How does the metabolism of tumour cells differ from that of normal cells.
Topics: Animals; Antineoplastic Agents; Energy Metabolism; Glutamine; Glycolysis; Humans; Mitochondria; Molecular Targeted Therapy; Neoplasms | 2013 |
Exploiting the bad eating habits of Ras-driven cancers.
Topics: Animals; Autophagy; Glucose; Glutamine; Humans; Lipid Metabolism; Metabolic Networks and Pathways; Neoplasms; Proteins; ras Proteins | 2013 |
Glutaminase regulation in cancer cells: a druggable chain of events.
Topics: Animals; Antineoplastic Agents; Glutaminase; Glutamine; Humans; Neoplasms | 2014 |
Altered glutamine metabolism and therapeutic opportunities for lung cancer.
Topics: Animals; Antineoplastic Agents; Energy Metabolism; Glutamine; Glycolysis; Humans; Neoplasms | 2014 |
Targeting metabolic changes in cancer: novel therapeutic approaches.
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; DNA-Binding Proteins; Fatty Acids; Glutamine; Humans; Isocitrate Dehydrogenase; Methotrexate; NAD; Neoplasms; Phosphopyruvate Hydratase; Signal Transduction; Tumor Suppressor Proteins | 2014 |
Who controls the ATP supply in cancer cells? Biochemistry lessons to understand cancer energy metabolism.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Energy Metabolism; Glutamine; Humans; Neoplasms; Oxidative Phosphorylation | 2014 |
Autophagy and cancer metabolism.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acids; Animals; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Proteins; Beclin-1; Cell Hypoxia; Cell Survival; Class III Phosphatidylinositol 3-Kinases; Glucose; Glutamine; Glycolysis; Humans; Membrane Proteins; Mitochondria; Neoplasms; Reactive Oxygen Species; Sequestosome-1 Protein; Stromal Cells | 2014 |
Impact of MYC in regulation of tumor cell metabolism.
Topics: Cell Proliferation; Genomic Instability; Glutamine; Glycolysis; Humans; Lipid Metabolism; Neoplasms; Proto-Oncogene Proteins c-myc; Tumor Microenvironment | 2015 |
Follow the ATP: tumor energy production: a perspective.
Topics: Adenosine Triphosphate; Autophagy; Carrier Proteins; Energy Metabolism; Glucose; Glucose Transporter Type 1; Glutamine; Hexokinase; Humans; Kidney Neoplasms; Membrane Proteins; NAD; Neoplasms; Pentose Phosphate Pathway; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2014 |
Proline metabolism and cancer: emerging links to glutamine and collagen.
Topics: Animals; Collagen; Glutamine; Humans; Neoplasms; Proline; Proto-Oncogene Mas | 2015 |
Redox control of glutamine utilization in cancer.
Topics: Amino Acids; Antineoplastic Agents; Glutamine; Glycolysis; Humans; Lipids; Mitochondria; Mitochondrial Proteins; NAD; NADP; NADP Transhydrogenase, AB-Specific; Neoplasms; Oxidation-Reduction; Pentose Phosphate Pathway; Reactive Oxygen Species | 2014 |
Mitochondrial sirtuins and their relationships with metabolic disease and cancer.
Topics: Aging; Animals; Carcinogenesis; Glutamine; Homeostasis; Humans; Metabolic Diseases; Mitochondrial Proteins; Neoplasms; Sirtuins | 2015 |
Famine versus feast: understanding the metabolism of tumors in vivo.
Topics: Animals; Energy Metabolism; Food; Glucose; Glutamine; Humans; Neoplasms; Starvation | 2015 |
Amino Acid transporters in cancer and their relevance to "glutamine addiction": novel targets for the design of a new class of anticancer drugs.
Topics: Amino Acid Transport Systems; Animals; Antineoplastic Agents; Glutamine; Humans; Molecular Targeted Therapy; Neoplasms | 2015 |
[Isotopic tracing technique in quantitative analysis of metabolic reprogramming in tumor cells].
Topics: Carbon Isotopes; Cell Line, Tumor; Citric Acid Cycle; Glutamine; Humans; Isotope Labeling; Mass Spectrometry; Neoplasms; Pentose Phosphate Pathway; Serine | 2015 |
Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
Topics: Acetates; Acetyl Coenzyme A; Cell Line, Tumor; Citrates; Citric Acid Cycle; Glucose; Glutamine; Humans; Hypoxia; Ketoglutaric Acids; Lipogenesis; Neoplasms | 2015 |
Glutaminolysis and autophagy in cancer.
Topics: Animals; Autophagy; Cell Proliferation; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Ketoglutaric Acids; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Neoplasm Recurrence, Local; Neoplasms; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases | 2015 |
The role of mammalian sirtuins in cancer metabolism.
Topics: Aging; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Glutamine; Glycolysis; Humans; Mice; Mitochondria; Neoplasms; Signal Transduction; Sirtuins | 2015 |
ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases.
Topics: Amidohydrolases; Animals; Asparagine; Glutamine; Humans; Hyperammonemia; Neoplasms; Nitrogen; Sulfur | 2016 |
Amino acid management in cancer.
Topics: Citric Acid Cycle; Glutamine; Humans; Neoplasms; Protein Biosynthesis; Serine; Signal Transduction; TOR Serine-Threonine Kinases | 2015 |
Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.
Topics: Animals; Apoptosis; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Humans; Hypoxia-Inducible Factor 1; Neoplasms; Proto-Oncogene Proteins c-myc; ras Proteins; Tumor Suppressor Protein p53 | 2015 |
The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism?
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Drug Discovery; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamine; Glycolysis; Humans; Mice; Molecular Targeted Therapy; Mutation; Neoplasm Transplantation; Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; RNA Interference; Signal Transduction | 2016 |
Oral Glutamine in Preventing Treatment-Related Mucositis in Adult Patients With Cancer: A Systematic Review.
Topics: Administration, Oral; Databases, Factual; Glutamine; Humans; Mucositis; Neoplasms; Randomized Controlled Trials as Topic; Risk Factors | 2016 |
Key Roles of Glutamine Pathways in Reprogramming the Cancer Metabolism.
Topics: Glioblastoma; Gluconeogenesis; Glutamine; Glutathione; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ketone Oxidoreductases; Neoplasms; Reactive Oxygen Species | 2015 |
Glutaminolysis as a target for cancer therapy.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Glutamine; Humans; Metabolic Networks and Pathways; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Small Molecule Libraries | 2016 |
Prophylaxis for mucositis induced by ambulatory chemotherapy: systematic review.
Topics: Allopurinol; Ambulatory Care; Anti-Inflammatory Agents; Antineoplastic Agents; Chlorhexidine; Controlled Clinical Trials as Topic; Cryotherapy; Fibroblast Growth Factor 7; Glutamine; Humans; Neoplasms; Oral Hygiene; Stomatitis | 2016 |
Glutamine at focus: versatile roles in cancer.
Topics: Animals; Energy Metabolism; Glutamine; Humans; Neoplasms; Signal Transduction | 2016 |
Glutamine transporters in mammalian cells and their functions in physiology and cancer.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Membrane; Glutamine; Humans; Mammals; Metabolism, Inborn Errors; Mice; Mice, Knockout; Molecular Targeted Therapy; Multigene Family; Neoplasm Proteins; Neoplasms; Substrate Specificity | 2016 |
Prevention and treatment of cancers by immune modulating nutrients.
Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes | 2016 |
Cancer metabolism: a therapeutic perspective.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment | 2017 |
From Krebs to clinic: glutamine metabolism to cancer therapy.
Topics: Adenosine Triphosphate; Citric Acid Cycle; Glutamine; Glutarates; Humans; Neoplasms | 2016 |
Long non-coding RNAs in cancer metabolism.
Topics: Animals; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Glucose; Glutamine; Humans; Neoplasms; RNA, Long Noncoding; Signal Transduction | 2016 |
[Metabolome analysis of solid tumors].
Topics: 4-Aminobutyrate Transaminase; beta-Alanine; Biomarkers, Tumor; Breast; Breast Neoplasms; Colonic Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutaminase; Glutamine; Humans; Metabolome; Neoplasms; Neoplasms, Hormone-Dependent; Ovarian Neoplasms; Ovary | 2016 |
Regional tumour glutamine supply affects chromatin and cell identity.
Topics: Animals; Cell Differentiation; Chromatin; Glutamine; Humans; Ketoglutaric Acids; Neoplasms; Tumor Microenvironment | 2016 |
Nutrients and the microenvironment to feed a T cell army.
Topics: Adaptation, Physiological; Animals; Biological Clocks; Cellular Microenvironment; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation; Glucose; Glutamine; Humans; Lymphocytes, Tumor-Infiltrating; Neoplasms; Signal Transduction; T-Lymphocyte Subsets | 2016 |
Caveolin-1 in the regulation of cell metabolism: a cancer perspective.
Topics: Animals; Autophagy; Caveolin 1; Energy Metabolism; Fatty Acids; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; Humans; Insulin Resistance; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Obesity | 2016 |
A Time for MYC: Metabolism and Therapy.
Topics: Animals; Cell Proliferation; Glucose; Glutamine; Humans; Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc | 2016 |
Metabolic Imaging of Glutamine in Cancer.
Topics: Glutamine; Humans; Molecular Imaging; Neoplasms; Positron-Emission Tomography | 2017 |
Glutaminolysis: A Hallmark of Cancer Metabolism.
Topics: Animals; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Glutamine; Humans; Mitochondria; Models, Biological; Neoplasms; Signal Transduction | 2017 |
Oral glutamine for the prevention of chemotherapy-induced peripheral neuropathy.
Topics: Administration, Oral; Antineoplastic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Glutamine; Humans; Neoplasms; Organoplatinum Compounds; Peripheral Nervous System Diseases; Taxoids; Vinca Alkaloids | 2008 |
The molecular determinants of de novo nucleotide biosynthesis in cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Models, Biological; Neoplasms; Pentose Phosphate Pathway; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Ribosemonophosphates | 2009 |
Dichotomic actions of glutamine in host versus tumour: an emerging concept.
Topics: Animals; Antineoplastic Agents; Glutamine; Glutathione; Humans; Neoplasms; Radiation Injuries | 2009 |
Hot topics in parenteral nutrition. A review of the use of glutamine supplementation in the nutritional support of patients undergoing bone-marrow transplantation and traditional cancer therapy.
Topics: Administration, Oral; Animals; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Dietary Supplements; Glutamine; Humans; Mucositis; Neoplasms; Parenteral Nutrition | 2009 |
Glutamine homeostasis and mitochondrial dynamics.
Topics: Animals; Brain; Glutaminase; Glutamine; Homeostasis; Humans; Mitochondria; Neoplasms; Oxidation-Reduction; Oxidative Stress | 2009 |
Mitochondrial metabolism and cancer.
Topics: Adenosine Triphosphate; Animals; Citric Acid Cycle; Glutamine; Glycolysis; Humans; Mitochondria; Models, Biological; NADP; Neoplasms; Reactive Oxygen Species | 2009 |
MYC-induced cancer cell energy metabolism and therapeutic opportunities.
Topics: Cell Transformation, Neoplastic; Energy Metabolism; Gene Expression Regulation, Neoplastic; Genes, myc; Glucose; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1; Neoplasms; Oxidative Phosphorylation; Proto-Oncogene Proteins c-myc; Signal Transduction | 2009 |
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.
Topics: Cell Proliferation; Cell Survival; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamine; Humans; Models, Biological; Neoplasms; Signal Transduction | 2010 |
Glutamine as indispensable nutrient in oncology: experimental and clinical evidence.
Topics: Administration, Oral; Antineoplastic Agents; Cachexia; Glutamine; Glutathione; Humans; Infusions, Intravenous; Neoplasms; Randomized Controlled Trials as Topic | 2010 |
L-glutamine use in the treatment and prevention of mucositis and cachexia: a naturopathic perspective.
Topics: Administration, Oral; Amino Acids; Animals; Antineoplastic Agents; Cachexia; Glutamine; Humans; Mucositis; Naturopathy; Neoplasms; Radiotherapy, Adjuvant; Stomatitis | 2009 |
Rethinking the Warburg effect with Myc micromanaging glutamine metabolism.
Topics: Animals; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Humans; MicroRNAs; Mitochondria; Models, Biological; Neoplasms; Proto-Oncogene Proteins c-myc | 2010 |
Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells.
Topics: Animals; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Isoenzymes; Metabolic Networks and Pathways; Mice; Models, Biological; Neoplasm Proteins; Neoplasms; Octamer Transcription Factor-3; Oncogene Proteins; Protein Interaction Mapping; Protein Serine-Threonine Kinases; Pyruvate Kinase; Rats; Tumor Suppressor Proteins | 2011 |
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells.
Topics: Adaptation, Biological; Cell Hypoxia; Cell Proliferation; Energy Metabolism; Gene Expression Regulation; Genes, myc; Glucose; Glutamine; Humans; Lactic Acid; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phosphatidylinositol 3-Kinase; Protein Serine-Threonine Kinases; Pyruvic Acid | 2011 |
Ammonia: a diffusible factor released by proliferating cells that induces autophagy.
Topics: Ammonia; Animals; Autophagy; Cell Proliferation; Glutamine; Humans; Hydrolases; Lysosomes; Neoplasms | 2010 |
Glutamine addiction: a new therapeutic target in cancer.
Topics: Animals; Glutamine; Humans; Mitochondria; Molecular Targeted Therapy; NADP; Neoplasms; Nucleotides; Protein Biosynthesis; TOR Serine-Threonine Kinases | 2010 |
Balancing biosynthesis and bioenergetics: metabolic programs in oncogenesis.
Topics: Cell Transformation, Neoplastic; Energy Metabolism; Fatty Acids; Glutamine; Glycolysis; Humans; Neoplasms; Signal Transduction | 2010 |
Hypoxia-induced metabolic shifts in cancer cells: moving beyond the Warburg effect.
Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Fatty Acids; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1; Lipid Metabolism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolomics; Mice; Mitochondria; Neoplasms; Oxidative Phosphorylation | 2011 |
Survival of the fittest: metabolic adaptations in cancer.
Topics: Adaptation, Biological; Animals; Cell Proliferation; Glucose; Glutamine; Humans; Mitochondria; Neoplasms | 2011 |
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes.
Topics: Adenosine Triphosphate; Cell Division; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glucose; Glutamine; Glycolysis; Humans; NADP; Neoplasms; Oncogenes; Pentose Phosphate Pathway; Signal Transduction | 2010 |
Regulation of protein metabolism by glutamine: implications for nutrition and health.
Topics: Animals; Burns; Critical Illness; Dietary Supplements; Glutamine; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Malnutrition; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Neoplasms; Nutritional Sciences; Proteins; Rats; Sepsis | 2011 |
Nutrition modulation of gastrointestinal toxicity related to cancer chemotherapy: from preclinical findings to clinical strategy.
Topics: Antineoplastic Agents; Cachexia; Fatty Acids, Omega-3; Gastrointestinal Diseases; Glutamine; Humans; Neoplasms; Nutritional Physiological Phenomena; Probiotics; Randomized Controlled Trials as Topic | 2011 |
Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment.
Topics: Animals; Autophagy; Biomarkers, Tumor; Caveolin 1; Cell Hypoxia; Cell Line, Tumor; Coculture Techniques; Female; Fibroblasts; Glutamine; Glycolysis; Humans; Mice; Mitochondria; Models, Biological; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Stromal Cells; Tumor Microenvironment | 2011 |
Glutamine: pleiotropic roles in tumor growth and stress resistance.
Topics: Autophagy; Glutamine; Models, Biological; Neoplasms; Oxidative Stress | 2011 |
Therapeutic targeting of cancer cell metabolism.
Topics: Animals; Glutamine; Glycolysis; Humans; Models, Biological; Neoplasms | 2011 |
Nutritional intervention for improving treatment tolerance in cancer patients.
Topics: Amino Acids; Arginine; Cachexia; Dietary Supplements; Fatty Acids, Omega-3; Feeding Behavior; Glutamine; Humans; Malnutrition; Neoplasms; Nutritional Status; Nutritional Support; Weight Loss | 2011 |
Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection.
Topics: Carbon; Cells, Cultured; Citric Acid; Citric Acid Cycle; Cytomegalovirus; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Glycolysis; Host-Pathogen Interactions; Humans; Ketoglutaric Acids; Mitochondria; Mitochondrial Membranes; Neoplasms; Phosphorylation | 2011 |
Dynamic nuclear polarization in metabolic imaging of metastasis: common sense, hypersense and compressed sensing.
Topics: Bicarbonates; Diagnostic Imaging; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neoplasm Metastasis; Neoplasms; Pyruvic Acid | 2010 |
An extended Myc network contributes to glucose homeostasis in cancer and diabetes.
Topics: Animals; Arrestins; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carrier Proteins; Cell Proliferation; Diabetes Mellitus; Glucose; Glutamine; Homeostasis; Humans; Insulin Resistance; Metabolic Networks and Pathways; Mice; Models, Biological; Neoplasms; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Thioredoxins; Transcription Factors | 2011 |
The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming.
Topics: Animals; Autophagy; Cell Hypoxia; Glutamine; Glycolysis; Humans; Lipogenesis; Neoplasms; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2011 |
Role of glutamine in cancer: therapeutic and imaging implications.
Topics: Animals; Glutamine; Humans; Molecular Imaging; Neoplasms | 2011 |
The relationships of nutrients, routes of delivery, and immunocompetence.
Topics: Arginine; Dietary Supplements; Enteral Nutrition; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Glutamine; Humans; Immune System; Immune Tolerance; Immunocompetence; Malnutrition; Neoplasms; Nutritional Support; Parenteral Nutrition; Parenteral Nutrition, Total; Perioperative Care; Surgical Procedures, Operative; Wounds and Injuries | 2011 |
Metabolic alterations in cancer cells and therapeutic implications.
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Genes, Tumor Suppressor; Glutamine; Glycolysis; Humans; Mitochondria; Mutation; Neoplasms; Neoplastic Stem Cells; Oncogenes; Oxidative Phosphorylation | 2011 |
Expanding targets for a metabolic therapy of cancer: L-asparaginase.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Drug Delivery Systems; Glutaminase; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
Targeting cancer metabolism: a therapeutic window opens.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Energy Metabolism; Enzymes; Glucose; Glutamine; Humans; Lactates; NAD; Neoplasms; Signal Transduction | 2011 |
[Treatment and prevention of cancer treatment related oral mucositis].
Topics: Antineoplastic Agents; Cryotherapy; Glutamine; Humans; Low-Level Light Therapy; Neoplasms; Oral Hygiene; Practice Guidelines as Topic; Severity of Illness Index; Stomatitis | 2011 |
Therapeutic targeting of Myc-reprogrammed cancer cell metabolism.
Topics: Glucose; Glutamine; Humans; Molecular Targeted Therapy; Neoplasms; Proto-Oncogene Proteins c-myc; Ribosomes | 2011 |
Tumor cell metabolism: an integral view.
Topics: Acidosis; Aerobiosis; Animals; Cell Hypoxia; Cell Proliferation; Glutamine; Glycolysis; Humans; Lipid Metabolism; Neoplasms; Nucleotides | 2011 |
Alterations of metabolic genes and metabolites in cancer.
Topics: Animals; Cell Transformation, Neoplastic; Energy Metabolism; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Glucose; Glutamine; Humans; Metabolic Networks and Pathways; Metabolome; Mutation; Neoplasms | 2012 |
Carbon source metabolism and its regulation in cancer cells.
Topics: Adenosine Triphosphate; Biomarkers, Tumor; Carbon; Cell Proliferation; Energy Metabolism; Gene Expression Regulation; Glucose; Glutamine; Humans; Hypoxia-Inducible Factor 1; MAP Kinase Signaling System; Neoplasms; Nitrogen; Oxygen; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Signal Transduction | 2012 |
Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis.
Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Energy Metabolism; Glucose; Glutamine; Humans; Mutation; Neoplasms; Oxidation-Reduction; Proto-Oncogene Proteins; Signal Transduction | 2012 |
The Xenopus oocyte: a model for studying the metabolic regulation of cancer cell death.
Topics: Animals; Apoptosis; Energy Metabolism; Glutamine; Humans; Lipid Metabolism; Metabolic Networks and Pathways; Neoplasms; Oocytes; Xenopus laevis | 2012 |
Normal and cancer cell metabolism: lymphocytes and lymphoma.
Topics: Animals; Genes, myc; Glucose; Glutamine; Humans; Lymphocyte Activation; Lymphoma; Mutation; Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; T-Lymphocytes | 2012 |
Glutamine for chemotherapy induced diarrhea: a meta-analysis.
Topics: Antidiarrheals; Antineoplastic Agents; Diarrhea; Enteral Nutrition; Glutamine; Humans; Neoplasms; Parenteral Nutrition; Randomized Controlled Trials as Topic | 2012 |
Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells.
Topics: Animals; Biological Transport; Citric Acid Cycle; Glucose; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Oncogenes; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2012 |
ATP-citrate lyase: a key player in cancer metabolism.
Topics: Animals; ATP Citrate (pro-S)-Lyase; Fatty Acids; Glucose; Glutamine; Humans; Metabolic Networks and Pathways; Mevalonic Acid; Models, Biological; Neoplasms | 2012 |
Glutamine as a supplemental treatment in pediatric and adult oncology patients.
Topics: Adult; Animals; Child; Dietary Supplements; Glutamine; Humans; Neoplasms; Parenteral Nutrition | 2012 |
Cancer metabolism: what we can learn from proteomic analysis by mass spectrometry.
Topics: Energy Metabolism; Glutamine; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lysosomes; Mass Spectrometry; Metabolomics; Neoplasms; Oxidative Stress; Proteomics; Pyruvate Kinase; Reactive Oxygen Species | 2012 |
Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.
Topics: Antineoplastic Agents; Energy Metabolism; Glutamine; Glycolysis; Humans; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidative Phosphorylation | 2013 |
Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force.
Topics: Angiogenesis Inhibitors; Endothelial Cells; Endothelium, Vascular; Glucose; Glutamine; Glycolysis; Humans; Hypoxia; Lactic Acid; Neoplasms; Neovascularization, Pathologic; Oxidation-Reduction | 2013 |
Nutrition in oncologic patients during antiblastic treatment.
Topics: Antineoplastic Agents; Cachexia; Complementary Therapies; Dietary Fats, Unsaturated; Dietary Proteins; Dietary Supplements; Glutamine; Hematopoietic Stem Cell Transplantation; Humans; Intestinal Mucosa; Muscle, Skeletal; Neoplasms; Nutritional Status; Proteoglycans; Stomatitis; Trametes | 2013 |
[Nutrition and tumoral growth].
Topics: Animals; Arginine; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Nucleotides; Rats | 2002 |
[Modulation of immunity in cancerous patient : an weapon with double edges?].
Topics: Animals; Arginine; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Nucleotides; Treatment Outcome | 2002 |
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil | 1963 |
Prevention of chemotherapy and radiation toxicity with glutamine.
Topics: Anthracyclines; Antineoplastic Agents; Dietary Supplements; Digestive System; Glutamine; Glutathione; Heart Diseases; Humans; Neoplasms; Paclitaxel; Radiation Injuries | 2003 |
Pathways from glutamine to apoptosis.
Topics: Apoptosis; Cell Proliferation; Glutamic Acid; Glutamine; Humans; Neoplasms; Neurons; Oxidative Stress; Signal Transduction | 2006 |
Cytoprotective agents used in the treatment of patients with cancer.
Topics: Amifostine; Antineoplastic Agents; Cytoprotection; Fibroblast Growth Factors; Glutamine; Humans; Mesna; Neoplasms; Razoxane | 2007 |
Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy.
Topics: Acetylcarnitine; Acupuncture Therapy; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Antioxidants; Calcium; Capsaicin; Evidence-Based Medicine; Exercise Therapy; Glutamine; Glutathione; Humans; Infrared Rays; Magnesium; Neoplasms; Nurse's Role; Nursing Research; Oncology Nursing; Patient Education as Topic; Peripheral Nervous System Diseases; Research Design; Sensory System Agents; Transcutaneous Electric Nerve Stimulation; Vitamin E | 2007 |
Brick by brick: metabolism and tumor cell growth.
Topics: Cell Proliferation; Fatty Acids; Glutamine; Glycolysis; Humans; Lipids; Models, Biological; Neoplasms; Ribosemonophosphates | 2008 |
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties | 1981 |
[Asparagine biosynthesis and tumor growth].
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases | 1982 |
Mitochondrial metabolism of glutamine and glutamate and its physiological significance.
Topics: Acidosis; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Cells, Cultured; Energy Metabolism; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Hepatic Encephalopathy; Humans; Intestine, Small; Intracellular Membranes; Kidney; Liver; Mitochondria; Mitochondria, Liver; Muscles; Neoplasms; Organ Specificity; Oxidation-Reduction; Rats | 1983 |
Current indications for intravenous nutritional support in oncology patients.
Topics: Animals; Arginine; Glutamine; Humans; Neoplasms; Nutrition Assessment; Parenteral Nutrition, Total; Preoperative Care; Randomized Controlled Trials as Topic; Treatment Outcome | 1995 |
Glutamine and cancer.
Topics: Antimetabolites, Antineoplastic; Cell Division; Diazooxonorleucine; Glutamine; Humans; Intestinal Mucosa; Intestines; Isoxazoles; Lymphocytes; Muscles; Neoplasms; Parenteral Nutrition, Total; Randomized Controlled Trials as Topic | 1993 |
Potential of antineoplastons in diseases of old age.
Topics: Aged; Aging; Animals; Antineoplastic Agents; Benzeneacetamides; Drug Combinations; Glutamine; Growth Inhibitors; Humans; Neoplasms; Peptides; Phenylacetates; Piperidones | 1995 |
Nutritional pharmacology and malignant disease: a therapeutic modality in patients with cancer.
Topics: Animals; Arginine; Cell Division; Fatty Acids, Essential; Glutamine; Humans; Immunity; Neoplasms; Nitrogen; Polyribonucleotides; Wound Healing | 1996 |
Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction.
Topics: Animals; CD4-Positive T-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Cysteine; Cystine; Fatigue Syndrome, Chronic; Glutamine; Glutathione; HIV Wasting Syndrome; Humans; Killer Cells, Natural; Models, Biological; Muscle, Skeletal; Muscular Diseases; Neoplasms; Sepsis; Wasting Syndrome; Wounds and Injuries | 1997 |
The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Energy Metabolism; Glutamine; Glycolysis; Humans; Neoplasm Metastasis; Neoplasms; Phosphates | 1997 |
[Cachexia in cancer: disturbances in the protein and aminoacid metabolism].
Topics: Amino Acids; Animals; Cachexia; Glutamine; Humans; Muscle, Skeletal; Neoplasms; Proteins | 1999 |
Therapeutic considerations of L-glutamine: a review of the literature.
Topics: Digestive System; Digestive System Physiological Phenomena; Glutamine; Humans; Neoplasms; Permeability; Wound Healing; Wounds and Injuries | 1999 |
Glutamine and arginine: immunonutrients for improved health.
Topics: Arginine; Burns; Dietary Supplements; Glutamine; Health Status; HIV Infections; Humans; Immunity, Cellular; Immunocompromised Host; Infections; Neoplasms | 2000 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
Is immune nutrition the Holy Grail for cancer patients?
Topics: Arginine; Fatty Acids, Unsaturated; Glutamine; Hospitalization; Humans; Immunotherapy; Length of Stay; Neoplasms; Nutritional Physiological Phenomena; Nutritional Support; Ornithine; Treatment Outcome | 2000 |
Glutamine metabolism in sepsis and infection.
Topics: Animals; Antineoplastic Agents; Bacterial Infections; Biological Transport; Clinical Trials as Topic; Colon; Disease Models, Animal; Forecasting; Glutamine; Humans; Intestine, Small; Liver; Lung; Muscle, Skeletal; Neoplasms; Sepsis; Tumor Cells, Cultured | 2001 |
Glutamine and cancer.
Topics: Biological Transport; Clinical Trials as Topic; Cloning, Molecular; Dietary Supplements; Gene Expression Regulation, Enzymologic; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Neoplasms; Nitrogen; Nutritional Status; Transglutaminases; Tumor Cells, Cultured | 2001 |
Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Diarrhea; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Infusions, Intravenous; Neoplasms; Parenteral Nutrition, Total | 2001 |
Nutritional and metabolic support in patients undergoing bone marrow transplantation.
Topics: Adult; Bone Marrow Transplantation; Child; Fatty Acids; Glutamine; Graft vs Host Disease; Hematologic Diseases; Humans; Liver Diseases; Neoplasms; Nutritional Support | 2002 |
Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death.
Topics: Animals; Antioxidants; Brain; Cell Death; Cell Division; Glutamine; Glutathione; Humans; Models, Biological; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2002 |
Relevance of glutamine metabolism to tumor cell growth.
Topics: Animals; Biological Transport, Active; Glutamine; Humans; Mitochondria; Neoplasms | 1992 |
Application of metabolic-control logic to the requirements for cell division.
Topics: Animals; Antineoplastic Agents; Cachexia; Cell Division; Glutamine; Glycolysis; Humans; Muscle Proteins; Neoplasms | 1990 |
Glutaminolysis and glycolysis interactions in proliferant cells.
Topics: Animals; Cell Division; Drug Interactions; Glucose; Glutamine; Humans; Neoplasms | 1990 |
Metabolic cooperativity within wounded tissue: hormone-nutrient interactions.
Topics: Cell Communication; Cell Division; Cells, Cultured; Fibroblasts; Glucose; Glutamine; Hormones; Humans; Neoplasms; Wound Healing | 1988 |
The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells.
Topics: Animals; Cell Division; Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; Intestinal Mucosa; Kinetics; Lymphocytes; Models, Biological; Neoplasms | 1985 |
Glutamine antagonists in chemotherapy.
Topics: Adult; Aminobutyrates; Animals; Asparaginase; Azaserine; Azo Compounds; Child; Diazooxonorleucine; Drug Combinations; Drug Interactions; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Hydroxylysine; Leukemia; Leukemia L1210; Liver; Methionine Sulfoximine; Mice; Neoplasms; Rats; RNA, Transfer | 1970 |
Hyperglycaemia and malignancy.
Topics: Animals; Glucose; Glutamine; Humans; Hyperglycemia; Neoplasms; Rats | 1968 |
[Plants with cytostatic effect].
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine | 1970 |
[Differentiation anomaly of tumor cells and enzymes].
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Fetus; Glucokinase; Glucosamine; Glutamine; Hexokinase; Isoenzymes; Isomerases; Liver; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases | 1971 |
25 trial(s) available for glutamine and Benign Neoplasms
Article | Year |
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Evaluation of an onco-diet on body composition and inflammatory status of dogs with mammary tumor-Pilot study.
Topics: Animals; Body Composition; C-Reactive Protein; Diet; Docosahexaenoic Acids; Dogs; Fatty Acids, Omega-3; Female; Glutamine; Insulin-Like Growth Factor I; Mastectomy; Neoplasms; Pilot Projects | 2023 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of
Topics: Adult; Aged; Biomarkers, Tumor; Cell Transformation, Neoplastic; Female; Fluorine Radioisotopes; Glutamine; Humans; Male; Middle Aged; Neoplasms; Positron-Emission Tomography; Tissue Distribution; United States; United States Food and Drug Administration | 2018 |
Arginine, glutamine, and fish oil supplementation in cancer patients treated with concurrent chemoradiotherapy: A randomized control study.
Topics: Arginine; Chemoradiotherapy; Dietary Supplements; Female; Fish Oils; Glutamine; Hematologic Diseases; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasms; Patient Compliance; Severity of Illness Index; Treatment Outcome | 2020 |
The impact of microbial immune enteral nutrition on the patients with acute radiation enteritis in bowel function and immune status.
Topics: Acute Disease; Aged; Calcitonin; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chromatography, High Pressure Liquid; Enteral Nutrition; Enteritis; Female; Fish Oils; Glutamine; Humans; Killer Cells, Natural; Lactulose; Male; Mannitol; Middle Aged; Neoplasms; Nutritional Status; Prealbumin; Probiotics; Protein Precursors; Serum Albumin | 2014 |
Effects of oral glutamine during abdominal radiotherapy on chronic radiation enteritis: a randomized controlled trial.
Topics: Administration, Oral; Aged; Chronic Disease; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Double-Blind Method; Enteritis; Female; Gastrointestinal Tract; Glutamine; Humans; Male; Middle Aged; Neoplasms; Nutritional Status; Radiotherapy | 2015 |
Glutamine-enriched nutrition does not reduce mucosal morbidity or complications after stem-cell transplantation for childhood malignancies: a prospective randomized study.
Topics: Adolescent; Analgesia; Child; Child, Preschool; Double-Blind Method; Female; Glutamine; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Mucositis; Mucous Membrane; Neoplasms; Odds Ratio; Parenteral Nutrition; Prospective Studies; Recurrence; Stem Cells; Treatment Outcome | 2011 |
The protective effects of glutamine on radiation-induced diarrhea.
Topics: Aged; Antidiarrheals; Diarrhea; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Turkey | 2013 |
Oral glutamine in paediatric oncology patients: a dose finding study.
Topics: Administration, Oral; Adolescent; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Glutamine; Humans; Inflammation; Infusions, Parenteral; Intestinal Mucosa; Intubation, Gastrointestinal; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Neoplasms; Safety | 2003 |
Pharmacokinetics of phenylacetate administered as a 30-min infusion in children with refractory cancer.
Topics: Adolescent; Adult; Antineoplastic Agents; Biotransformation; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Resistance, Neoplasm; Female; Glutamine; Half-Life; Humans; Infant; Infusions, Intravenous; Male; Models, Biological; Neoplasms; Phenylacetates; Spectrophotometry, Ultraviolet | 2003 |
Effects of oral glutamine supplementation on children with solid tumors receiving chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Body Weights and Measures; Child; Child, Preschool; Female; Glutamine; Humans; Immune System; Immunologic Factors; Infant; Male; Neoplasms; Nutritional Status; Parenteral Nutrition; Treatment Outcome | 2006 |
The effect of oral glutamine on 5-fluorouracil/leucovorin-induced mucositis/stomatitis assessed by intestinal permeability test.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromium Radioisotopes; Edetic Acid; Female; Fluorouracil; Glutamine; Humans; Intestinal Absorption; Leucovorin; Male; Middle Aged; Mucositis; Neoplasms; Permeability; Severity of Illness Index; Stomatitis; Treatment Outcome | 2007 |
The effect of high-dose enteral glutamine on the incidence and severity of mucositis in paediatric oncology patients.
Topics: Administration, Oral; Adolescent; Ammonia; Antineoplastic Agents; Child; Child, Preschool; Enteral Nutrition; Female; Gastrointestinal Tract; Glutamine; Humans; Male; Mucositis; Neoplasms; Parenteral Nutrition; Young Adult | 2009 |
A randomized, double-blind, placebo-controlled trial of a beta-hydroxyl beta-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122).
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Arginine; Cachexia; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Placebos; Plethysmography; Quality of Life; Statistics, Nonparametric; Treatment Outcome; Valerates | 2008 |
Prevention of docetaxel- or paclitaxel-associated taste alterations in cancer patients with oral glutamine: a randomized, placebo-controlled, double-blind study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Docetaxel; Double-Blind Method; Dysgeusia; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Paclitaxel; Risk Factors; Taste; Taxoids; Treatment Outcome | 2008 |
Disposition of phenylbutyrate and its metabolites, phenylacetate and phenylacetylglutamine.
Topics: Adult; Aged; Female; Glutamine; Humans; Male; Middle Aged; Models, Biological; Neoplasms; Phenylacetates; Phenylbutyrates | 1995 |
A phase I and pharmacokinetic study of intravenous phenylacetate in patients with cancer.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Administration Schedule; Female; Glioblastoma; Glutamine; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Neoplasms; Phenylacetates | 1994 |
Oral glutamine to prevent chemotherapy induced stomatitis: a pilot study.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cyclophosphamide; Dacarbazine; Double-Blind Method; Doxorubicin; Etoposide; Female; Fluorouracil; Glutamine; Humans; Ifosfamide; Male; Neoplasms; Pilot Projects; Placebos; Sarcoma, Kaposi; Stomatitis; Vincristine | 1996 |
Toxicological study on antineoplastons A-10 and AS2-1 in cancer patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Child; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Phenylacetates; Piperidones | 1995 |
Metabolic and immune effects of dietary arginine, glutamine and omega-3 fatty acids supplementation in immunocompromised patients.
Topics: Adult; Arginine; Burns; CD4-CD8 Ratio; Dietary Supplements; Enteral Nutrition; Fatty Acids, Omega-3; Female; Glutamine; Humans; Immunocompromised Host; Immunoglobulins; Lymphocyte Count; Male; Middle Aged; Neoplasms; Nutritional Status; Phenotype; Prospective Studies; Treatment Outcome; Wounds and Injuries | 1998 |
A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies.
Topics: Adult; Aged; Amino Acids; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Electrolytes; Female; Glucose; Glutamine; Humans; Isoxazoles; Male; Middle Aged; Neoplasms; Parenteral Nutrition Solutions; Solutions; Thrombocytopenia; Treatment Outcome | 1998 |
A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Edema; Fatigue; Female; Glutamine; Humans; Hypocalcemia; Male; Middle Aged; Nausea; Neoplasms; Nervous System Diseases; Phenylacetates; Phenylbutyrates; Treatment Outcome; Vomiting | 2001 |
A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule.
Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Fatigue; Female; Glutamine; Humans; Hypokalemia; Infusions, Intravenous; Male; Metabolic Clearance Rate; Nausea; Neoplasms; Neutropenia; Patient Dropouts; Phenylacetates; Phenylbutyrates; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors; Tumor Cells, Cultured; Uric Acid | 2001 |
Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.
Topics: Aged; Arginine; Body Composition; Cachexia; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Muscle, Skeletal; Neoplasms; Treatment Outcome; Valerates | 2002 |
Phase I study of succinylated acinetobacter L-glutaminase-L-asparaginase.
Topics: Acinetobacter; Adolescent; Alkalosis, Respiratory; Amidohydrolases; Asparagine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Glutamine; Humans; Hyperglycemia; Leukemia, Lymphoid; Male; Neoplasms | 1979 |
247 other study(ies) available for glutamine and Benign Neoplasms
Article | Year |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement.
Topics: Animals; Biomarkers, Pharmacological; Biomarkers, Tumor; Chromatography, Liquid; Drug Development; Glutamine; Glycine; Mass Spectrometry; Metabolic Networks and Pathways; Mice; Neoplasms; Ribonucleotides | 2021 |
Glutamine promotes escape from therapy-induced senescence in tumor cells.
Topics: A549 Cells; Amino Acid Transport System ASC; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamine; Humans; MCF-7 Cells; Minor Histocompatibility Antigens; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Nitrogen; Nucleotides; Senescence-Associated Secretory Phenotype; Tumor Escape | 2021 |
CISD3 inhibition drives cystine-deprivation induced ferroptosis.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cystine; Disease Progression; Ferroptosis; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutamine; Homeostasis; Humans; Iron; Iron-Sulfur Proteins; Lipid Peroxides; Mice, Nude; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Mitophagy; Neoplasms; Organophosphorus Compounds; Piperazines; Ubiquinone; Xenograft Model Antitumor Assays | 2021 |
SnapShot: Cancer metabolism.
Topics: Amino Acids; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; Metabolic Networks and Pathways; Neoplasms; Nucleotides | 2021 |
Glutamine Metabolism Regulators Associated with Cancer Development and the Tumor Microenvironment: A Pan-Cancer Multi-Omics Analysis.
Topics: Biomarkers, Tumor; Carcinogenesis; Datasets as Topic; DNA Copy Number Variations; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Kaplan-Meier Estimate; Male; Metabolic Networks and Pathways; Neoplasms; Polymorphism, Single Nucleotide; RNA-Seq; Tumor Microenvironment | 2021 |
Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment.
Topics: Animals; Cancer-Associated Fibroblasts; Cell Line; Citric Acid Cycle; Collagen; Disease Susceptibility; Enzyme Activation; Fibrosis; Gene Expression Regulation, Enzymologic; Glutamine; Humans; Lactic Acid; Mice; Neoplasms; Protein Biosynthesis; Pyruvate Carboxylase; Transforming Growth Factor beta; Tumor Microenvironment | 2021 |
Succinate receptor 1 inhibits mitochondrial respiration in cancer cells addicted to glutamine.
Topics: Cell Line, Tumor; Cell Respiration; Glutamine; HEK293 Cells; Humans; Mitochondria; Neoplasms; Receptors, G-Protein-Coupled; Transfection | 2022 |
New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
Topics: Crystallography; Enzyme Inhibitors; Glutaminase; Glutamine; Neoplasms; Sulfides; Temperature; Thiadiazoles | 2022 |
Systemically Applicable Glutamine-Functionalized Polymer Exerting Multivalent Interaction with Tumors Overexpressing ASCT2.
Topics: Amino Acid Transport System ASC; Glutamine; Humans; Minor Histocompatibility Antigens; Neoplasms; Polymers | 2021 |
A biomimetic ZIF nanoagent for synergistic regulation of glutamine metabolism and intracellular acidosis of cancer.
Topics: Animals; Biomimetic Materials; Cell Survival; Enzyme Inhibitors; Glutamine; Humans; Imidazoles; Lactic Acid; MCF-7 Cells; Nanoparticles; Neoplasms; Sulfides; Thiadiazoles; Zeolites | 2022 |
Tumor-derived exosomes co-delivering aggregation-induced emission luminogens and proton pump inhibitors for tumor glutamine starvation therapy and enhanced type-I photodynamic therapy.
Topics: Cell Line, Tumor; Exosomes; Glutamine; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents; Proton Pump Inhibitors | 2022 |
MRI assessment of glutamine uptake correlates with the distribution of glutamine transporters and cancer stem cell markers.
Topics: Amino Acid Transport System ASC; Animals; Glutamine; Humans; Magnetic Resonance Imaging; Mice; Minor Histocompatibility Antigens; Neoplasms; Neoplastic Stem Cells | 2022 |
Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells.
Topics: Cell Line, Tumor; Citric Acid Cycle; Glutamine; Isocitrate Dehydrogenase; Neoplasms; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11 | 2022 |
VGLL3 increases the dependency of cancer cells on de novo nucleotide synthesis through GART expression.
Topics: Carbon-Nitrogen Ligases; Cell Line, Tumor; Glutamine; Humans; Neoplasms; Nucleotides; Phosphoribosylglycinamide Formyltransferase; Transcription Factors | 2022 |
Macrophage mitochondrial fission improves cancer cell phagocytosis induced by therapeutic antibodies and is impaired by glutamine competition.
Topics: Cytophagocytosis; Cytoskeletal Proteins; Glutamine; Humans; Macrophages; Mitochondrial Dynamics; Neoplasms; Phagocytosis; Protein Kinase C-theta; Wiskott-Aldrich Syndrome Protein | 2022 |
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth.
Topics: Ammonia; Glucose; Glutamine; Humans; Insulin; Lipogenesis; Neoplasms; Sterol Regulatory Element Binding Protein 1; Sterols | 2022 |
Characterizing unexpected interactions of a glutamine transporter inhibitor with members of the SLC1A transporter family.
Topics: Amino Acid Transport System ASC; Amino Acid Transport Systems; Amino Acids, Neutral; Glutamine; Humans; Minor Histocompatibility Antigens; Neoplasms | 2022 |
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors.
Topics: Glutamine; Humans; Neoplasms; Nucleic Acid Synthesis Inhibitors; Ribosomes; RNA Precursors; RNA, Ribosomal; Tumor Suppressor Protein p53 | 2022 |
Trabectedin suppresses escape from therapy-induced senescence in tumor cells by interfering with glutamine metabolism.
Topics: Amino Acid Transport System ASC; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; Glutamine; Humans; Minor Histocompatibility Antigens; Neoplasms; Neoplastic Stem Cells; Trabectedin | 2022 |
Biomimetic Nanoplatform Loading Type I Aggregation-Induced Emission Photosensitizer and Glutamine Blockade to Regulate Nutrient Partitioning for Enhancing Antitumor Immunotherapy.
Topics: Biomimetics; Cell Line, Tumor; Glutamine; Humans; Immunologic Factors; Immunotherapy; Neoplasms; Nutrients; Photosensitizing Agents; Tumor Microenvironment | 2022 |
Sirpiglenastat (DRP-104) Induces Antitumor Efficacy through Direct, Broad Antagonism of Glutamine Metabolism and Stimulation of the Innate and Adaptive Immune Systems.
Topics: Amino Acids, Essential; Cell Line, Tumor; Diazooxonorleucine; Glutamine; Humans; Immune System; Neoplasms; Prodrugs; Tumor Microenvironment | 2022 |
The mitochondrial enzyme FAHD1 regulates complex II activity in breast cancer cells and is indispensable for basal BT-20 cells in vitro.
Topics: Apoptosis; Cell Line; Glutamine; Hydrolases; Mitochondria; Neoplasms | 2022 |
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors.
Topics: Animals; Electron Transport; Electron Transport Complex I; Glucose; Glutamine; Humans; Isotopes; Mice; NAD; Neoplasms; Saccharomyces cerevisiae Proteins | 2022 |
Serum diamine oxidase activity derived from response to chemotherapy affects adverse events and serum amino acid levels.
Topics: Amine Oxidase (Copper-Containing); Antineoplastic Agents; Glutamine; Humans; Intestinal Mucosa; Neoplasms; Prospective Studies; Quality of Life | 2022 |
A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes.
Topics: Carbon; Glucose; Glutamine; Hexosamines; Humans; Hypoglycemic Agents; Lactates; Lipids; Neoplasms; Tumor Microenvironment | 2022 |
Inhibition of alanine-serine-cysteine transporter 2-mediated auto-enhanced photodynamic cancer therapy of co-nanoassembly between V-9302 and photosensitizer.
Topics: Animals; Cell Line, Tumor; Cysteine; Glutamine; Mice; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species | 2023 |
Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells.
Topics: Adenosine Diphosphate Ribose; Aminooxyacetic Acid; ATP Citrate (pro-S)-Lyase; Glutamates; Glutamine; Humans; Ketoglutaric Acids; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Neoplasms; Oleic Acids; Oxaloacetates; Phosphatidic Acids; Proto-Oncogene Proteins c-akt; Transaminases | 2022 |
Hepatic glutamine synthetase controls N
Topics: Ammonia; Animals; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Homeostasis; Humans; Liver; Mammals; Mice; Neoplasms | 2023 |
Probabilistic model checking of cancer metabolism.
Topics: Cell Hypoxia; Glucose; Glutamine; Humans; Models, Statistical; Neoplasms | 2022 |
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.
Topics: CD8-Positive T-Lymphocytes; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Humans; Neoplasms; Prodrugs | 2022 |
α-ketoglutarate suppresses immediate early gene expression in cancer cells.
Topics: Citric Acid Cycle; Combined Modality Therapy; Genes, Immediate-Early; Glutamine; Ketoglutaric Acids; Neoplasms | 2022 |
Cancer cell survival depends on collagen uptake into tumor-associated stroma.
Topics: Animals; Cell Survival; Collagen; Glutamine; Humans; Immunoconjugates; Mice; Microfilament Proteins; Neoplasms; Receptors, Cell Surface | 2022 |
Glutamine-dependent effects of nitric oxide on cancer cells subjected to hypoxia-reoxygenation.
Topics: Energy Metabolism; Glutamine; Humans; Hypoxia; Ketoglutaric Acids; Neoplasms; Nitric Oxide | 2023 |
Bivalves Transmissible Neoplasia: Biochemical Aspects of Contagious Cancer in a Clam Macoma Balthica.
Topics: Amino Acids; Animals; Bivalvia; Glutamine; Glutathione; Humans; Hydrocortisone; Neoplasms; Protein Carbonylation; Tandem Mass Spectrometry | 2022 |
Bioinspired nanocatalytic tumor therapy by simultaneous reactive oxygen species generation enhancement and glutamine pathway-mediated glutathione depletion.
Topics: Glutamine; Glutathione; Gold; Humans; Hydrogen Peroxide; Metal Nanoparticles; Neoplasms; Reactive Oxygen Species | 2022 |
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells.
Topics: Adenosine Triphosphate; Amino Acid Transport System ASC; Energy Metabolism; Glucose; Glutamine; Glycolysis; HSP90 Heat-Shock Proteins; Humans; Minor Histocompatibility Antigens; Mitochondria; Molecular Chaperones; Neoplasms | 2023 |
Tumor-targeted nanoflowers regulate glutamine metabolism and amplify oxidative stress for synergistic therapy.
Topics: Cell Line, Tumor; Glutamine; Humans; Neoplasms; Oxidative Stress | 2023 |
Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss.
Topics: Adenosine Triphosphatases; Dietary Supplements; DNA Helicases; Glucose Transporter Type 1; Glutamine; Humans; Neoplasms; Nuclear Proteins; Transcription Factors | 2023 |
Synthesis, Characterization, and Biological Evaluation of Radiolabeled Glutamine Conjugated Polymeric Nanoparticles: A Simple Approach for Tumor Imaging.
Topics: Animals; Glutamine; Nanoparticles; Neoplasms; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Technetium; Tissue Distribution | 2023 |
Detachable MOF-Based Core/Shell Nanoreactor for Cancer Dual-Starvation Therapy With Reversing Glucose and Glutamine Metabolisms.
Topics: Cell Line, Tumor; Glucose; Glucose Oxidase; Glutamine; Humans; Metal-Organic Frameworks; Nanotechnology; Neoplasms; Reactive Oxygen Species; Tumor Microenvironment | 2023 |
Differential Effects of Glutamine Inhibition Strategies on Antitumor CD8 T Cells.
Topics: Animals; CD8-Positive T-Lymphocytes; Diazooxonorleucine; Glutamine; Mice; Neoplasms | 2023 |
SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity.
Topics: Amino Acid Transport System A; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; CD8-Positive T-Lymphocytes; Dendritic Cells; Glutamine; Neoplasms; Proto-Oncogene Proteins; Signal Transduction; Tumor Suppressor Proteins | 2023 |
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Topics: Amino Acid Transport System ASC; Cancer-Associated Fibroblasts; Glutamine; Humans; Melanoma; Minor Histocompatibility Antigens; Neoplasms; Tumor Microenvironment; Ultrasonography | 2023 |
Glutamine Influences Type-1 Conventional Dendritic Cell Antitumor Immunity.
Topics: CD8-Positive T-Lymphocytes; Dendritic Cells; Glutamine; Humans; Neoplasms | 2023 |
Boosting the therapy of glutamine-addiction glioblastoma by combining glutamine metabolism therapy with photo-enhanced chemodynamic therapy.
Topics: Cell Line, Tumor; Cell Membrane; Glioblastoma; Glucose; Glutamine; Glutathione; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Tumor Microenvironment | 2023 |
Nursing care approaches to oral mucositis in pediatric oncology clinics: a cross-sectional study from Türkiye.
Topics: Benzydamine; Child; Chlorhexidine; Cross-Sectional Studies; Glutamine; Humans; Mucositis; Neoplasms; Stomatitis | 2023 |
L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor.
Topics: Animals; Cachexia; Collagen; Dietary Supplements; Fibroblast Growth Factor 2; Glutamine; Neoplasms; Rats; Rats, Wistar | 2023 |
Discovery of
Topics: Diazooxonorleucine; Esters; Glutamine; Humans; Neoplasms; Prodrugs | 2023 |
Application of metabolomics technologies toward cancer prognosis and therapy.
Topics: Animals; Biomarkers, Tumor; Glucose; Glutamine; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Neoplasms | 2019 |
Causes and Consequences of A Glutamine Induced Normoxic HIF1 Activity for the Tumor Metabolism.
Topics: Acetylation; Ascorbic Acid; Carbonic Anhydrase IX; Cell Line, Tumor; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; High-Throughput Nucleotide Sequencing; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Protein Stability; RNA, Small Interfering | 2019 |
Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Humans; Metabolic Networks and Pathways; Metabolome; Metabolomics; Neoplasms | 2019 |
T cell flexibility points to a metabolic checkpoint for cancer therapy.
Topics: Glutamine; Humans; Immunotherapy; Neoplasms; Programmed Cell Death 1 Receptor; T-Lymphocytes; Tumor Escape | 2020 |
Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Drug Synergism; Female; Glutaminase; Glutamine; Glycolysis; Humans; Hydrogen-Ion Concentration; Mice; Neoplasms; Pentose Phosphate Pathway; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sulfides; Thiadiazoles; Xenograft Model Antitumor Assays | 2020 |
Glutamine Skipping the Q into Mitochondria.
Topics: Amino Acid Transport System ASC; Animals; Cell Proliferation; Cytoplasm; Glutaminase; Glutamine; Humans; Mitochondria; Neoplasms | 2020 |
A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells.
Topics: Amino Acid Transport System ASC; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cellular Reprogramming; Female; Glutamine; Humans; Mice; Mice, Inbred BALB C; Minor Histocompatibility Antigens; Mitochondria; Neoplasms; Tumor Hypoxia | 2020 |
Co-delivery of 2-Deoxyglucose and a glutamine metabolism inhibitor V9302 via a prodrug micellar formulation for synergistic targeting of metabolism in cancer.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Drug Liberation; Drug Synergism; Female; Glucose; Glutamine; Humans; Mice, Inbred BALB C; Micelles; Neoplasms; Polyethylene Glycols; Prodrugs; Tissue Distribution | 2020 |
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
Topics: A549 Cells; Animals; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Female; Glutamine; HeLa Cells; Hep G2 Cells; Humans; Lipogenesis; MCF-7 Cells; Metabolic Networks and Pathways; Mice; Mice, Nude; Neoplasms; Proline | 2020 |
Tumor Microenvironment, Metabolism, and Immunotherapy.
Topics: Animals; Azo Compounds; Caproates; Glutamine; Humans; Immunotherapy; Mice; Neoplasms; T-Lymphocytes; Tumor Microenvironment | 2020 |
Aspirin Mitigated Tumor Growth in Obese Mice Involving Metabolic Inhibition.
Topics: Animals; Aspirin; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diet, High-Fat; Feeding Behavior; Glucose; Glutamine; Leukocytes; Male; Mice, Inbred C57BL; Mice, Obese; Neoplasms | 2020 |
A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer.
Topics: Amidophosphoribosyltransferase; Animals; Biosynthetic Pathways; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Humans; Metabolomics; Mice, Nude; Models, Biological; Molecular Targeted Therapy; Neoplasms; Nitrogen; Prognosis | 2020 |
Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells.
Topics: Activating Transcription Factor 4; Antimetabolites; Cell Death; Deoxyglucose; Epithelial Cells; Gene Expression Regulation; Glucose; Glutamine; HeLa Cells; Humans; Inflammation; Interleukin-6; Interleukin-8; Macrophages; Metformin; Neoplasms; NF-kappa B; Promoter Regions, Genetic; Starvation; Stress, Physiological | 2020 |
Metabolic Reprogramming in Health and Disease.
Topics: Cellular Reprogramming; Glutamine; Glycolysis; Humans; Lipid Metabolism; Mitochondria; Neoplasms | 2020 |
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclic N-Oxides; Female; Glutamine; Glycolysis; Heterocyclic Compounds; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Docking Simulation; NAD; Neoplasms; Oxidative Phosphorylation; Pyruvic Acid; Reactive Oxygen Species; Serine; Spin Labels; Xenograft Model Antitumor Assays | 2020 |
[Effects of dynamic nutrition support on energy metabolism, immune function and stress response after oral and maxillofacial tumor surgery].
Topics: Energy Metabolism; Enteral Nutrition; Glutamine; Humans; Neoplasms; Postoperative Period | 2020 |
Glutamine deprivation alters the origin and function of cancer cell exosomes.
Topics: Animals; Cell Proliferation; Drosophila melanogaster; Drosophila Proteins; Exosomes; Glutamine; MAP Kinase Signaling System; Mechanistic Target of Rapamycin Complex 1; Neoplasms; rab GTP-Binding Proteins | 2020 |
Extracellular vesicles: eat glutamine and spit acidic bubbles.
Topics: Cell Communication; Exosomes; Extracellular Vesicles; Glutamine; Neoplasms; Signal Transduction | 2020 |
Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment.
Topics: Cell Survival; Extracellular Matrix; Glutamine; Glycolysis; Humans; Neoplasms | 2020 |
Targeting glutamine metabolism as an effective means to promote allograft acceptance while inhibit tumor growth.
Topics: Allografts; Animals; Antineoplastic Agents; Cell Growth Processes; Cell Line, Tumor; Glutamine; Graft Rejection; Graft Survival; Growth Inhibitors; Humans; Immune Tolerance; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Targeted Therapy; Neoplasms; Transplantation, Homologous | 2020 |
Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity.
Topics: Aged; Animals; Antibodies, Monoclonal; Apoptosis; B7-H1 Antigen; Cell Proliferation; Female; Glutamine; Glutathione; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasms; Sarcoplasmic Reticulum Calcium-Transporting ATPases; T-Lymphocytes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Targeting Glutamine Metabolism and PD-L1: A Novel Anti-tumor Pas de Deux.
Topics: B7-H1 Antigen; Glutamine; Humans; Neoplasms; NF-kappa B | 2020 |
Time-resolved non-invasive metabolomic monitoring of a single cancer spheroid by microfluidic NMR.
Topics: Alanine; Glucose; Glutamine; Humans; Hydrogen-Ion Concentration; Lab-On-A-Chip Devices; Lactic Acid; Magnetic Resonance Spectroscopy; MCF-7 Cells; Metabolomics; Microfluidic Analytical Techniques; Neoplasms; Spheroids, Cellular | 2021 |
Cell-programmed nutrient partitioning in the tumour microenvironment.
Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Female; Glucose; Glutamine; Humans; Lipid Metabolism; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Myeloid Cells; Neoplasms; Nutrients; Tumor Microenvironment | 2021 |
Glutamine Metabolism in Cancer.
Topics: Citric Acid Cycle; Energy Metabolism; Glutamine; Glycolysis; Humans; Metabolic Networks and Pathways; Neoplasms | 2021 |
Bridging the Metabolic Parallels Between Neurological Diseases and Cancer.
Topics: Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Neoplasms; Organophosphorus Compounds | 2021 |
Metabolic Intersection of Cancer and Cardiovascular Diseases: Opportunities for Cancer Therapy.
Topics: Cardiovascular Diseases; Glutamic Acid; Glutaminase; Glutamine; Humans; Neoplasms | 2021 |
Can tumor cells take it all away?
Topics: Cell Proliferation; Citric Acid Cycle; Glucose; Glutamine; Glycolysis; Humans; Neoplasms | 2021 |
DDIT3 Directs a Dual Mechanism to Balance Glycolysis and Oxidative Phosphorylation during Glutamine Deprivation.
Topics: Animals; Apoptosis Regulatory Proteins; Electron Transport Complex IV; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; HCT116 Cells; Humans; Mice; Mice, Knockout; Neoplasms; Oxidative Phosphorylation; Phosphoric Monoester Hydrolases; Transcription Factor CHOP; Ubiquinone | 2021 |
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion.
Topics: Actin Cytoskeleton; Actins; Axl Receptor Tyrosine Kinase; Cell Line, Tumor; Cell Proliferation; Cell Surface Extensions; Enzyme Activation; Focal Adhesions; Glioblastoma; Glutamine; HEK293 Cells; Humans; Intercellular Signaling Peptides and Proteins; Models, Biological; Neoplasm Invasiveness; Neoplasms; Phosphatidylinositol 3-Kinases; Pinocytosis; Protein Binding; Proto-Oncogene Proteins; rac1 GTP-Binding Protein; Receptor Protein-Tyrosine Kinases; Signal Transduction | 2021 |
Is glucose the scapegoat for tumor evasion?
Topics: Glucose; Glutamine; Glycolysis; Humans; Neoplasms; Tumor Microenvironment | 2021 |
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Topics: Animals; Glucose; Glutamine; Lactic Acid; Mice; NADP; Neoplasms; Pentose Phosphate Pathway | 2021 |
Back to the Future: Therapeutic Targeting of Cancer Cell Metabolism.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Oncogenes; Oxidative Phosphorylation; Serine | 2017 |
SNAT7 is the primary lysosomal glutamine exporter required for extracellular protein-dependent growth of cancer cells.
Topics: Amino Acid Transport Systems, Neutral; Glutamine; HeLa Cells; Humans; Intracellular Membranes; Lysosomes; Neoplasm Proteins; Neoplasms; Tumor Microenvironment | 2017 |
Kr-POK (ZBTB7c) regulates cancer cell proliferation through glutamine metabolism.
Topics: Animals; Cell Death; Cell Line; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Proteins; RNA, Small Interfering; STAT1 Transcription Factor; Transcription Factors; Transcription, Genetic | 2017 |
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus.
Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cell Proliferation; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Herpesvirus 8, Human; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides | 2017 |
A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect.
Topics: Animals; Cell Proliferation; Computer Simulation; Glucose; Glutamine; Humans; Lactic Acid; Metabolic Flux Analysis; Metabolic Networks and Pathways; Models, Biological; Neoplasms | 2017 |
Topics: Cell Line, Tumor; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glutamine; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Metabolomics; Neoplasms; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-myc; Pyridines; TOR Serine-Threonine Kinases | 2017 |
Systematic analyses of glutamine and glutamate metabolisms across different cancer types.
Topics: Gene Expression Regulation, Neoplastic; Glutamic Acid; Glutamine; Humans; Neoplasms | 2017 |
Dietary glutamine, glutamate and mortality: two large prospective studies in US men and women.
Topics: Adult; Aged; Cardiovascular Diseases; Dietary Supplements; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Life Style; Male; Middle Aged; Neoplasms; Prospective Studies; Risk Factors; United States | 2018 |
Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Topics: Amino Acid Sequence; Amino Acid Transport System ASC; Amino Acids; Animals; Binding Sites; Escherichia coli; Glutamine; Mutagenesis, Site-Directed; Neoplasms; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Substrate Specificity; Xenopus laevis | 2018 |
Glutamine-derived 2-hydroxyglutarate is associated with disease progression in plasma cell malignancies.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Citric Acid Cycle; Disease Progression; DNA-Binding Proteins; Glucose; Glutamine; Glutarates; Glycolysis; Humans; Lactic Acid; Multiple Myeloma; Multivariate Analysis; Neoplasms; Plasma Cells; Transcription Factors | 2018 |
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Disease Models, Animal; Glutamine; HCT116 Cells; Humans; Mice; Minor Histocompatibility Antigens; Neoplasms; Oxidative Stress; Signal Transduction; Small Molecule Libraries | 2018 |
CHTM1, a novel metabolic marker deregulated in human malignancies.
Topics: Base Sequence; Biomarkers, Tumor; Carcinogenesis; Cytosol; Energy Metabolism; Glucose; Glutamine; HEK293 Cells; Humans; Lipid Metabolism; MCF-7 Cells; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Neoplasms; Nutrients; Signal Transduction; Tumor Cells, Cultured | 2018 |
[Effect of Oral Glutamine on Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: An Evidence-Based Appraisal].
Topics: Administration, Oral; Antineoplastic Agents; Evidence-Based Nursing; Glutamine; Humans; Neoplasms; Peripheral Nervous System Diseases | 2018 |
Rational cell culture optimization enhances experimental reproducibility in cancer cells.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Glutaminase; Glutamine; Humans; Metabolomics; Neoplasms; Reproducibility of Results; Research Design; Thiadiazoles | 2018 |
Inhibition of mTOR complexes protects cancer cells from glutamine starvation induced cell death by restoring Akt stability.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Glutamine; Humans; Mice; Neoplasms; NIH 3T3 Cells; Protein Kinase Inhibitors; Protein Stability; Proteolysis; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Ubiquitination | 2018 |
Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Benzophenanthridines; Cell Line, Tumor; Cell Proliferation; Chloroquine; Glutaminase; Glutamine; Humans; Lipolysis; Metabolomics; Neoplasms; Oxidative Stress | 2018 |
The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Topics: A549 Cells; Animals; Glucose; Glutamine; Glycerol; Heterografts; Humans; Lactic Acid; Male; Mice; Mice, Nude; Neoplasms; Phosphoenolpyruvate Carboxykinase (ATP); Phospholipids | 2018 |
Antineoplastons: when is enough enough?
Topics: Administration, Intravenous; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Evidence-Based Medicine; Glutamine; Humans; Neoplasms; Neurotoxicity Syndromes; Patient Safety; Phenylacetates; Quackery; Risk Assessment; Treatment Outcome | 2018 |
A hypothetical method for controlling highly glycolytic cancers and metastases.
Topics: Blood Glucose; Cell Proliferation; Cerebrovascular Circulation; Deoxyglucose; Diet, Ketogenic; Glutamine; Glycolysis; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Models, Theoretical; Neoplasm Metastasis; Neoplasms | 2018 |
A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3.
Topics: Adaptation, Physiological; Animals; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Excitatory Amino Acid Transporter 1; Female; Glutamine; Humans; Mice, Inbred BALB C; Neoplasms; Starvation; Tumor Suppressor Protein p53 | 2018 |
Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
Topics: Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Cell Line; Cell Proliferation; Cell Survival; Citric Acid Cycle; Cytosol; Female; Glutamine; Humans; Mice, Inbred C57BL; Mitochondria; Neoplasms | 2018 |
Theanine, an antitumor promoter, induces apoptosis of tumor cells via the mitochondrial pathway.
Topics: Apoptosis; Caspase 3; Caspase 8; Cell Proliferation; Cytochromes c; DNA Damage; Gene Expression Regulation, Neoplastic; Glutamates; Glutamine; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neoplasms; Signal Transduction; Tea | 2018 |
Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors.
Topics: Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Glucose; Glutamine; Glycolysis; Humans; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Metabolome; Neoplasms; Oxygen; Tumor Microenvironment | 2018 |
Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer.
Topics: Adolescent; Adult; Animals; Argininosuccinate Synthase; Bone Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Child; Down-Regulation; Gene Expression Profiling; Glutamine; Humans; Hydrogen-Ion Concentration; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, SCID; Neoplasms; Osteosarcoma; Oxidation-Reduction; Young Adult | 2019 |
Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia.
Topics: Acetyl Coenzyme A; Ammonia; Animals; Carbon; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glucose; Glutamine; HEK293 Cells; Humans; Lactic Acid; Lipogenesis; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Nude; Neoplasms; Nitrogen; Nucleotides; Orotic Acid; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2019 |
γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity.
Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Enzyme Activation; gamma-Glutamyltransferase; Glutamine; Humans; Hydrolysis; Metabolic Detoxication, Phase I; Neoplasms; Reactive Oxygen Species | 2019 |
Overview of Glutamine Dependency and Metabolic Rescue Protocols.
Topics: Adaptation, Biological; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Metabolic Networks and Pathways; Neoplasms; Oxygen; Signal Transduction | 2019 |
HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis.
Topics: Adult; Aged; Aged, 80 and over; Aspartate Aminotransferase, Cytoplasmic; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Female; Glutamine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Neoplasms; Male; Middle Aged; Mitochondrial Proteins; Neoplasms; Oxidation-Reduction; Tumor Suppressor Proteins; Von Hippel-Lindau Tumor Suppressor Protein | 2019 |
Enhanced metabolic activities for ATP production and elevated metabolic flux via pentose phosphate pathway contribute for better CIK cells expansion.
Topics: Adenosine Triphosphate; Cell Culture Techniques; Cell Proliferation; Cytokine-Induced Killer Cells; Fetal Blood; Glucose; Glucose Transporter Type 1; Glutamine; Glycolysis; Humans; Immunotherapy, Adoptive; Models, Biological; Neoplasms; Oxygen Consumption; Pentose Phosphate Pathway | 2019 |
Synthesis and preliminary evaluation of a novel glutamine derivative: (2S,4S)4-[
Topics: Apoptosis Regulatory Proteins; Cell Line, Tumor; Crown Ethers; Fluorine Radioisotopes; Glutamine; Humans; Neoplasms; Radiopharmaceuticals; Ribonucleoproteins | 2019 |
Deprivation of glutamine in cell culture reveals its potential for treating cancer.
Topics: Animals; BALB 3T3 Cells; Cell Culture Techniques; Cell Transformation, Neoplastic; Culture Media; Glutamine; Mice; Neoplasms | 2019 |
Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells.
Topics: Animals; Carbon Isotopes; Cell Compartmentation; Cell Hypoxia; Citrate (si)-Synthase; Citric Acid; Citric Acid Cycle; Cytosol; Glutamine; HeLa Cells; Humans; Isocitrate Dehydrogenase; Metabolic Flux Analysis; Metabolome; Mice; Mitochondria; Neoplasms; Subcellular Fractions; Succinate Dehydrogenase | 2019 |
BAG3 promotes autophagy and glutaminolysis via stabilizing glutaminase.
Topics: Adaptor Proteins, Signal Transducing; Ammonia; Apoptosis Regulatory Proteins; Autophagy; Enzyme Stability; Glutaminase; Glutamine; Hep G2 Cells; Humans; MCF-7 Cells; Mitochondria; Neoplasms; Proteasome Endopeptidase Complex; Proteolysis; Sirtuins; Transfection; Ubiquitination | 2019 |
Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth.
Topics: Benzeneacetamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Female; Glucose; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutaminase; Glutamine; Glycolysis; Humans; Male; Neoplasms; Thiadiazoles | 2019 |
Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair.
Topics: Animals; Cell Line, Tumor; DNA Damage; DNA Repair; Glutamate-Ammonia Ligase; Glutamine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasms; Nucleotides; Radiation Tolerance | 2019 |
Immunosuppressive Immature Myeloid Cell Generation Is Controlled by Glutamine Metabolism in Human Cancer.
Topics: Animals; Antigen Presentation; B7-H1 Antigen; Cell Line, Tumor; Cell Proliferation; Female; Glutamine; Glycolysis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Myeloid Cells; Neoplasms; Signal Transduction; T-Lymphocytes; Tumor Microenvironment | 2019 |
The axis of MAPK1/3-XBP1u-FOXO1 controls autophagic dynamics in cancer cells.
Topics: Autophagy; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Forkhead Transcription Factors; Glutamine; HCT116 Cells; Humans; Models, Biological; Neoplasms; Phosphorylation; Proteolysis; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors | 2013 |
Cancer control via glucose and glutamine deprivation.
Topics: Endothelium, Vascular; Glucose; Glutamine; Humans; Lactic Acid; Neoplasms; Neovascularization, Pathologic | 2013 |
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Topics: Activating Transcription Factors; Animals; Cell Proliferation; Embryo, Mammalian; Energy Metabolism; Glutamate Dehydrogenase; Glutamine; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Mitochondrial Proteins; Multiprotein Complexes; Neoplasm Transplantation; Neoplasms; Sirtuins; TOR Serine-Threonine Kinases; Transcription, Genetic; Transplantation, Heterologous; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Ubiquitination | 2013 |
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.
Topics: Animals; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Carbon Isotopes; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Fatty Acids; Glucose; Glutamine; Humans; Lipogenesis; Mice; Mice, Knockout; Neoplasms; Oxygen Consumption; Phospholipids; Pinocytosis; ras Proteins; Stearoyl-CoA Desaturase | 2013 |
Metabolism: Metabolic block.
Topics: Animals; DNA Damage; Female; Glutamine; Humans; Male; Mitochondria; Mitochondrial Proteins; Neoplasms; Neoplasms, Experimental; Sirtuins | 2013 |
Cancer metabolism in breadth and depth.
Topics: Animals; Benzeneacetamides; Cell Differentiation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Glioma; Glutamine; Hematopoiesis; Humans; Imidazoles; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Metabolic Networks and Pathways; Neoplasms; Oncogene Protein p21(ras); Pancreatic Neoplasms; Phenylurea Compounds; Proto-Oncogene Proteins; ras Proteins; Sulfonamides | 2013 |
Synthesis and radiolabelling of DOTA-linked glutamine analogues with ⁶⁷,⁶⁸Ga as markers for increased glutamine metabolism in tumour cells.
Topics: Biomarkers; Cell Line, Tumor; Gallium Radioisotopes; Glutamine; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Neoplasms; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals | 2013 |
Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling.
Topics: Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Respiration; Energy Metabolism; Galactose; Glucose; Glutamine; Glycolysis; HCT116 Cells; Humans; Mice; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxygen Consumption; PC12 Cells; Pyruvic Acid; Rats; Substrate Specificity | 2014 |
MYC, metabolism, cell growth, and tumorigenesis.
Topics: Carcinogenesis; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, p53; Glucose; Glutamine; Humans; Lipid Metabolism; Mitochondria; Neoplasms; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Ribosomes; Signal Transduction; Transcription Factors | 2013 |
Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio.
Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Glutamine; Glycerol; Hepatic Encephalopathy; Humans; Liver; Neoplasms; Phenylacetates; Phenylbutyrates; Randomized Controlled Trials as Topic; Urea Cycle Disorders, Inborn | 2013 |
[Leucine sensing in the regulation of autophagy: glutamate dehydrogenase is on the way].
Topics: Autophagy; Glutamate Dehydrogenase; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Models, Biological; Multiprotein Complexes; Neoplasms; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
Hexokinase 2 as oncotarget.
Topics: Animals; Glucose; Glutamine; Hexokinase; Humans; Mice; Molecular Targeted Therapy; Neoplasms | 2013 |
Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Cell Line, Transformed; Cell Line, Tumor; Glutamine; Humans; Metabolic Networks and Pathways; Mice; Models, Biological; Neoplasms; Oxidative Phosphorylation; Systems Biology | 2013 |
[Efficacy of AboundTM for hand-foot syndrome caused by capecitabine].
Topics: Aged; Antimetabolites, Antineoplastic; Arginine; Butyrates; Capecitabine; Deoxycytidine; Female; Fluorouracil; Glutamine; Hand-Foot Syndrome; Humans; Hydroxy Acids; Male; Middle Aged; Neoplasms | 2013 |
The many faces of sirtuins: Sirtuins and the Warburg effect.
Topics: Antineoplastic Agents; Glutamine; Glycolysis; Humans; Longevity; Metabolic Networks and Pathways; Models, Biological; NAD; Neoplasms; Sirtuins | 2014 |
Transient state microscopy probes patterns of altered oxygen consumption in cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Eosine Yellowish-(YS); Female; Fluorescent Dyes; Glucose; Glutamine; Glycolysis; Humans; MCF-7 Cells; Metabolic Networks and Pathways; Microscopy, Fluorescence; Neoplasms; Oxidative Phosphorylation; Oxygen Consumption | 2014 |
Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques.
Topics: Antimicrobial Cationic Peptides; Cell Line, Tumor; Cell Membrane; Glutamine; Humans; Isotope Labeling; Lipoproteins; Microscopy, Atomic Force; Nanotechnology; Neoplasms; Spectrometry, Mass, Secondary Ion; Tissue Distribution | 2014 |
13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells.
Topics: Biochemistry; Carbon Isotopes; Cell Hypoxia; Cells, Cultured; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Humans; Lipids; Neoplasms | 2014 |
Blocking anaplerotic entry of glutamine into the TCA cycle sensitizes K-Ras mutant cancer cells to cytotoxic drugs.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Capecitabine; Cell Cycle Checkpoints; Cell Line, Tumor; Citric Acid Cycle; Cytotoxins; Deoxycytidine; Fluorouracil; Glutamine; Humans; Mutation; Neoplasms; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins | 2015 |
The SIRT1/HIF2α axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy.
Topics: Acidosis; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Chronic Disease; Glucose; Glutamine; Glycolysis; Humans; Neoplasms; Sirtuin 1 | 2014 |
Gln-362 of angiopoietin-2 mediates migration of tumor and endothelial cells through association with α5β1 integrin.
Topics: Angiopoietin-2; Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Endothelial Cells; Gene Expression Regulation; Glutamine; Humans; Integrin alpha5beta1; Integrins; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Plasmids; Protein Structure, Tertiary; Receptor, TIE-2 | 2014 |
Asparagine protects tumor cells from glutamine depletion-induced cell death.
Topics: Asparagine; Aspartate-Ammonia Ligase; Cell Death; Glutamine; Humans; Neoplasms; Transcription Factor CHOP | 2014 |
Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention.
Topics: Allosteric Site; Ammonia; Antineoplastic Agents; Catalysis; Catalytic Domain; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Glutamic Acid; Glutamine; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kidney; Neoplasm Metastasis; Neoplasms; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases | 2015 |
Is glutamine deficiency the link between inflammation, malnutrition, and fatigue in cancer patients?
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Electric Impedance; Fatigue; Female; Glutamine; Humans; Inflammation; Male; Malnutrition; Middle Aged; Motor Activity; Neoplasms; Nutrition Assessment; Nutritional Status; Prognosis; Surveys and Questionnaires | 2015 |
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.
Topics: Alcohol Oxidoreductases; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Respiration; DNA-Binding Proteins; Glutamine; Glycolysis; Homeostasis; Humans; Hydrogen-Ion Concentration; Methionine; Mice; Mice, Nude; Mitochondrial Proteins; Models, Biological; Neoplasms; Sirtuins; Xenograft Model Antitumor Assays | 2015 |
Evolving paradigms in the nutritional support of critically ill surgical patients.
Topics: Arginine; Burns; Cachexia; Critical Illness; Enteral Nutrition; Fish Oils; Gastrointestinal Tract; Glutamine; Humans; Infusions, Intravenous; Lipids; Microbiota; Multiple Organ Failure; Muscle, Skeletal; Neoplasms; Parenteral Nutrition; Perioperative Care; Protein-Energy Malnutrition; Stress, Physiological | 2015 |
Metabolic reprogramming as a continuous changing behavior of tumor cells.
Topics: Acidosis; Cell Hypoxia; Cell Line, Tumor; Glucose; Glutamine; Glycolysis; Humans; Neoplasms; Tumor Microenvironment | 2015 |
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
Topics: Adaptation, Physiological; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Gluconeogenesis; Glucose; Glutamine; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Mitochondria; Neoplasms; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (ATP); Purines; Pyruvic Acid; Serine | 2015 |
Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.
Topics: Acetylglucosamine; Cellular Senescence; DNA; DNA Repair; Epigenesis, Genetic; Genomic Instability; Glutamine; Glycolysis; Humans; MCF-7 Cells; Neoplasms; RNA Interference | 2016 |
Q-ing tumor glutaminase for therapy.
Topics: Animals; Enzyme Inhibitors; Glutaminase; Glutamine; Humans; Mice; Neoplasms | 2015 |
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Glutaminase; Glutamine; HeLa Cells; Humans; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Monocarboxylic Acid Transporters; Neoplasms; Oxidation-Reduction; Symporters | 2016 |
Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch.
Topics: Adenosine Triphosphate; Apoptosis; Blotting, Western; Cell Proliferation; Chromatin Immunoprecipitation; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Glutaminase; Glutamine; Glycolysis; HeLa Cells; Hep G2 Cells; Homeodomain Proteins; Humans; MCF-7 Cells; Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Transforming Growth Factor beta; Tumor Cells, Cultured | 2016 |
Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis.
Topics: Animals; Anoikis; Autophagy; Cell Line, Tumor; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum Stress; Glucose; Glutamine; Glycolysis; Humans; Mice; Neoplasms; Starvation; Transcriptome | 2016 |
Automated synthesis of [(18)F](2S,4R)-4-fluoroglutamine on a GE TRACERlab™ FX-N Pro module.
Topics: Automation; Chemistry Techniques, Synthetic; Drug Stability; Fluorine Radioisotopes; Glutamine; Humans; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Technology, Radiologic | 2016 |
Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Topics: Cell Adhesion; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Citric Acid; Contact Inhibition; Cytosol; Extracellular Matrix; Glucose; Glutamic Acid; Glutamine; Homeostasis; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spheroids, Cellular | 2016 |
mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells.
Topics: Adenosine Triphosphate; Animals; Carcinoma; Cell Line, Tumor; Citric Acid Cycle; Combined Modality Therapy; Cytokines; Deoxyglucose; Drug Resistance, Neoplasm; Drug Synergism; Energy Metabolism; Everolimus; Female; Glucose-6-Phosphate Isomerase; Glutaminase; Glutamine; Glycolysis; Hep G2 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolomics; Mice; Mice, Nude; Molecular Targeted Therapy; Multiprotein Complexes; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Pentose Phosphate Pathway; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; RNA, Small Interfering; TOR Serine-Threonine Kinases; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2016 |
Glycoholics Anonymous: Cancer Sobers Up with mTORC1.
Topics: Glucose; Glutamine; Glycolysis; Humans; Neoplasms; Pentose Phosphate Pathway | 2016 |
The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy.
Topics: Animals; Base Sequence; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Humans; MCF-7 Cells; Mice; Molecular Sequence Data; Neoplasms; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA Interference | 2016 |
Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation.
Topics: Acetyl Coenzyme A; Acetylation; Acidosis; Animals; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cellular Reprogramming; Electron Transport Complex I; Fatty Acids; Female; Glutamine; Histones; Humans; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Mice, Nude; Mitochondria; Models, Biological; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species | 2016 |
Supplementation with L-glutamine prevents tumor growth and cancer-induced cachexia as well as restores cell proliferation of intestinal mucosa of Walker-256 tumor-bearing rats.
Topics: Animals; Cachexia; Carcinogenesis; Cell Proliferation; Dietary Supplements; Glutamine; Humans; Intestinal Mucosa; Neoplasms; Rats | 2016 |
Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.
Topics: Animals; Cell Line, Tumor; Enzyme Activation; Glutaminase; Glutamine; Humans; Mice; Neoplasm Proteins; Neoplasms; NIH 3T3 Cells; Protein Multimerization; Protein Structure, Secondary | 2016 |
Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine.
Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Glucose; Glutamine; Glutathione; Humans; Neoplasms; Oxidation-Reduction; Pyruvic Acid; Reactive Oxygen Species | 2016 |
Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.
Topics: Animals; DNA Methylation; Glutamine; Histone Demethylases; Histones; Humans; Ketoglutaric Acids; Methylation; Methyltransferases; Neoplasms | 2016 |
Experimental Cancer Cachexia Changes Neuron Numbers and Peptide Levels in the Intestine: Partial Protective Effects after Dietary Supplementation with L-Glutamine.
Topics: Cachexia; Cell Line, Tumor; Dietary Supplements; Glutamine; Humans; Intestinal Mucosa; Neoplasms; Neurons | 2016 |
Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction.
Topics: Animals; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation, Neoplastic; Glutamine; HCT116 Cells; Humans; Mice; Mice, Nude; Mutant Proteins; Mutation; Neoplasms; Stress, Physiological; Tumor Suppressor Protein p53; Up-Regulation | 2017 |
Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells.
Topics: Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Genes, ras; Glutamine; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Mutation; Neoplasms; Phenotype; Transaminases; Tumor Suppressor Protein p53 | 2016 |
The Quid Pro Quo of the Tumor/Stromal Interaction.
Topics: Caveolin 1; Fibroblasts; Glutamine; Humans; Neoplasms; Stromal Cells | 2016 |
Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism.
Topics: Adenosine Triphosphate; Biomass; Cell Line, Tumor; Glucose; Glutamine; Glycolysis; Humans; Metabolic Flux Analysis; Metabolic Networks and Pathways; Metabolome; Neoplasms; Phenotype; Protein Biosynthesis; Systems Biology | 2017 |
Regulation of stem-like cancer cells by glutamine through β-catenin pathway mediated by redox signaling.
Topics: A549 Cells; Animals; Asparaginase; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glutamine; Glutathione; Humans; Mice; Neoplasm Proteins; Neoplasms; Neoplastic Stem Cells; Oxidation-Reduction; Side-Population Cells; Wnt Signaling Pathway | 2017 |
PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Dihydroorotate Dehydrogenase; DNA Damage; DNA Replication; Enzyme Inhibitors; Fibroblasts; Gene Knockout Techniques; Glutamine; Humans; Metabolic Networks and Pathways; Mice; Neoplasms; Oxidoreductases Acting on CH-CH Group Donors; PTEN Phosphohydrolase; Pyrimidines | 2017 |
Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Gene Amplification; Glucose; Glutamine; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lung Neoplasms; Malate Dehydrogenase; Neoplasms | 2017 |
Finding an "Achilles' heel" of cancer: the role of glucose and glutamine metabolism in the survival of transformed cells.
Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Glucose; Glutamine; Humans; Mice; Neoplasms | 2008 |
Effect of added phosphate on glutamine desamidation in tumors.
Topics: Glutamine; Humans; Neoplasms; Phosphates | 1948 |
Tuning glutamine binding modes in Gd-DOTA-based probes for an improved MRI visualization of tumor cells.
Topics: Animals; Contrast Media; Cyclization; Glutamine; Hepatocytes; Heterocyclic Compounds; Magnetic Resonance Imaging; Neoplasms; Organometallic Compounds; Rats; Tumor Cells, Cultured | 2009 |
When good nutrients go bad: can we predict nutrient-drug interactions?
Topics: Cardiovascular Diseases; Complementary Therapies; Dietary Supplements; Fatty Acids, Omega-3; Food-Drug Interactions; Glutamine; Humans; Models, Immunological; Neoplasms | 2009 |
Enteral administration of alanyl-[2-(15)N]glutamine contributes more to the de novo synthesis of arginine than does intravenous infusion of the dipeptide in humans.
Topics: Arginine; Body Mass Index; Citrulline; Dipeptides; Enteral Nutrition; Female; Gastrointestinal Diseases; Glutamine; Humans; Infusions, Intravenous; Isotope Labeling; Male; Middle Aged; Neoplasms; Nitrogen Isotopes | 2009 |
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors | 2010 |
MYC, microRNAs and glutamine addiction in cancers.
Topics: E2F1 Transcription Factor; Glutaminase; Glutamine; Humans; MicroRNAs; Neoplasms; Proto-Oncogene Proteins c-myc; S Phase | 2009 |
PKM2 tyrosine phosphorylation and glutamine metabolism signal a different view of the Warburg effect.
Topics: Animals; Cell Proliferation; Citric Acid Cycle; Glutamine; Glycolysis; Humans; Models, Biological; Neoplasms; Phosphorylation; Protein Multimerization; Pyruvate Kinase; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Tyrosine | 2009 |
High glucose concentrations attenuate hypoxia-inducible factor-1alpha expression and signaling in non-tumor cells.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Glucose; Glutamine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ketoglutaric Acids; Macrophages; Mice; Muscle Development; Myoblasts; Neoplasms; Osmolar Concentration; Signal Transduction | 2010 |
Desamidation of glutamine and asparagine in normal and neoplastic hepatic tissues.
Topics: Amino Acids; Asparagine; Glutamine; Liver Neoplasms; Neoplasms | 1947 |
Q&A: Cancer: clues from cell metabolism.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Lactic Acid; Metabolic Networks and Pathways; Neoplasms; Oxidative Phosphorylation; Oxygen | 2010 |
Oncology's energetic pipeline.
Topics: Animals; Antineoplastic Agents; Dichloroacetic Acid; Drug Industry; Energy Metabolism; Glutamine; Glycolysis; Humans; Neoplasms | 2010 |
Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells.
Topics: Alanine; Ammonia; Aspartic Acid; Carbon; Cell Line, Tumor; Cell Proliferation; Energy Metabolism; Glucose; Glutamine; Humans; Ketoglutaric Acids; Metabolism; Mitochondria; Neoplasms; Nitrogen; Nucleic Acids; Stress, Physiological | 2010 |
Glutaminolysis: supplying carbon or nitrogen or both for cancer cells?
Topics: Amino Acids; Carbon; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycolysis; Humans; Neoplasms; Nitrogen; Proto-Oncogene Proteins c-myc | 2010 |
High-glycolytic cancers and their interplay with the body's glucose demand and supply cycle.
Topics: Animals; Blood Glucose; Brain; Cell Line, Tumor; Fatty Acids; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; Humans; Hypoxia; Immune System; Lactates; Models, Biological; Neoplasms; Treatment Outcome | 2011 |
Synthesis of optically pure 4-fluoro-glutamines as potential metabolic imaging agents for tumors.
Topics: Biological Transport; Cell Line, Tumor; Glutamine; Halogenation; Humans; Isotope Labeling; Molecular Imaging; Neoplasms; Optical Phenomena; Stereoisomerism; Substrate Specificity | 2011 |
Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect.
Topics: Biomass; Cell Proliferation; Energy Metabolism; Gene Expression; Genome, Human; Glutamine; Glycolysis; Humans; Metabolic Networks and Pathways; Neoplasms | 2011 |
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.
Topics: Animals; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Citric Acid Cycle; Fibroblasts; Flow Cytometry; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Isotope Labeling; Mice; Neoplasms; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins p21(ras) | 2011 |
Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Topics: Acetyl Coenzyme A; Animals; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Citric Acid; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Fumarate Hydratase; Glucose; Glutamine; Humans; Isocitrate Dehydrogenase; Kidney Neoplasms; Mice; Mitochondria; NADP; Neoplasms | 2011 |
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
Topics: Carboxylic Acids; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citrates; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypoxia-Inducible Factor 1; Immunoblotting; Isocitrate Dehydrogenase; Ketoglutaric Acids; Neoplasms; Oxidation-Reduction; RNA Interference | 2011 |
Breathless cancer cells get fat on glutamine.
Topics: Glucose; Glutamine; Lipids; Neoplasms | 2012 |
Glutamine and the tumor microenvironment: understanding the mechanisms that fuel cancer progression.
Topics: Autophagy; Glutamine; Humans; Mitochondria; Neoplasms | 2011 |
Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Caveolin 1; Cell Communication; Cell Line, Tumor; Chloroquine; Coculture Techniques; Epithelial Cells; Fibroblasts; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; MCF-7 Cells; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phosphoric Monoester Hydrolases; Stromal Cells; Tamoxifen; Tumor Microenvironment | 2011 |
[Guidelines for specialized nutritional and metabolic support in the critically-ill patient. Update. Consensus of the Spanish Society of Intensive Care Medicine and Coronary Units-Spanish Society of Parenteral and Enteral Nutrition (SEMICYUC-SENPE): oncoh
Topics: Cachexia; Critical Care; Critical Illness; Dietary Fats; Eicosapentaenoic Acid; Energy Intake; Energy Metabolism; Enteral Nutrition; Glutamine; Humans; Inflammation; Neoplasms; Nutritional Requirements; Parenteral Nutrition; Postoperative Care; Societies, Medical; Societies, Scientific; Spain | 2011 |
Complexity of metabolic cancer control: can we exploit the superior metabolic position of glucose?
Topics: Autophagy; Glutamine; Humans; Mitochondria; Neoplasms | 2012 |
Emerging concepts: linking hypoxic signaling and cancer metabolism.
Topics: Cell Hypoxia; Glucose; Glutamine; Humans; Neoplasms; Signal Transduction | 2012 |
Understanding tumor cell metabolism: the secret to winning the war (burg) on cancer?
Topics: Animals; Glucose; Glutamine; Glycolysis; Humans; Neoplasms; Signal Transduction | 2012 |
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Topics: Animals; Cell Division; Glucose; Glutamine; Mice; Mice, Transgenic; Neoplasms; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2012 |
The real face of HIF1α in the tumor process.
Topics: Ammonia; Glucose Transporter Type 1; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Quaternary Ammonium Compounds | 2012 |
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
Topics: Animals; Antineoplastic Agents; Benzamides; Biological Availability; Cell Proliferation; Cytidine Triphosphate; Diphenylamine; Drosophila melanogaster; Drug Screening Assays, Antitumor; Glutamine; Isoxazoles; Neoplasms; Pharmacogenetics; Pilot Projects | 2013 |
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity.
Topics: Amino Acid Transport System ASC; Amino Acid Transport Systems; Animals; Antineoplastic Agents; Binding Sites; Computer Simulation; Cysteine; Dose-Response Relationship, Drug; Glutamine; Kinetics; Minor Histocompatibility Antigens; Neoplasms; Proteolipids; Rats; Structure-Activity Relationship; Thiazoles | 2012 |
Multiple metabolic alterations exist in mutant PI3K cancers, but only glucose is essential as a nutrient source.
Topics: Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Enzyme Activation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Targeting; Glucose; Glutamine; Glycolysis; Humans; Metabolome; Mutant Proteins; Mutation; Neoplasms; Phosphatidylinositol 3-Kinases; Up-Regulation | 2012 |
c-Myc and cancer metabolism.
Topics: Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; Humans; Mitochondria; Molecular Targeted Therapy; Neoplasms; Proto-Oncogene Proteins c-myc | 2012 |
Molecular pathways: regulation of metabolism by RB.
Topics: Animals; Carbohydrate Metabolism; Glucose; Glutamine; Humans; Mitochondria; Molecular Targeted Therapy; Neoplasms; Retinoblastoma Protein | 2012 |
A proposed role for glutamine in cancer cell growth through acid resistance.
Topics: Alkanesulfonic Acids; Ammonia; Cell Proliferation; Glutaminase; Glutamine; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kidney; Liver; MCF-7 Cells; Neoplasms; Piperazines | 2013 |
The growth response of mammalian cells in tissue culture to L-glutamine and L-glutamic acid.
Topics: Animals; Glutamates; Glutamic Acid; Glutamine; Humans; Neoplasms; Tissue Culture Techniques | 1956 |
Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine.
Topics: Animals; Asparagine; Biochemical Phenomena; Carcinoma 256, Walker; Glutamine; Humans; In Vitro Techniques; Neoplasms | 1956 |
8-Hydroxylysine: an inhibitor of glutamine and protein synthesis by the Ehrlich ascites carcinoma cell.
Topics: Ascites; Glutamine; Hydroxylysine; Lysine; Neoplasms; Protein Biosynthesis; Proteins | 1957 |
The inhibition by glutamine of glutamyl transferase formation in cultures of human cells.
Topics: Aminoacyltransferases; Glutamine; Humans; Neoplasms; Transferases | 1958 |
Specific rotation of phenylacetylglutamine excreted by cancer patients and normal subjects.
Topics: Encephalomyelitis; Glutamine; Neoplasms; Rotation | 1958 |
Biochemical changes during experimental carcinogenesis. II. Glutamine and glutamic acid metabolism in perfused livers of azo dye-fed rats.
Topics: Animals; Azo Compounds; Carcinogenesis; Carcinogens; Glutamates; Glutamine; Liver Neoplasms; Neoplasms; Rats | 1959 |
Effect of glutamine analogs on amino acid incorporation into protein of some normal and neoplastic cells in vitro.
Topics: Amino Acids; Glutamine; In Vitro Techniques; Neoplasms; Proteins | 1959 |
Glutamine metabolism of normal and malignant cells cultivated in synthetic media.
Topics: Cell Count; Glutamine; Humans; Neoplasms; Neoplasms, Experimental; Research Design; Tissue Culture Techniques | 1959 |
The effect of glucose on glutamine utilization by Ehrlich ascites tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Glucose; Glutamine; Humans; Neoplasms | 1961 |
Effect of anaerobiosis and addition of keto acids on glutamine utilization by Ehrlich ascites-tumor cells.
Topics: Anaerobiosis; Ascites; Biochemical Phenomena; Glutamine; Kernicterus; Keto Acids; Neoplasms | 1960 |
A study of free amino acids and of glutamine synthesis in tumor-bearing rats.
Topics: Amino Acids; Animals; Glutamine; Neoplasms; Rats | 1960 |
[POTENTIAL ANTICANCER AGENTS. I. SYNTHESIS OF DERIVATIVES OF GLUTAMINE AND RELATED COMPOUNDS].
Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Glutamine; Neoplasms; Neoplasms, Experimental; Research | 1963 |
ASPARAGINE-C14 AND GLUTAMINE-C14 FROM ANIMAL CELL PROTEIN AND THEIR CHEMICAL DEGRADATION.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Glutamine; Ion Exchange Resins; Malates; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Proteins; Research; Sarcoma; Sarcoma, Experimental | 1963 |
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
[INCORPORATION OF FORMATE-C14 IN THE BASES OF THE NUCLEIC ACIDS OF STICKER'S TUMOR IN VIVO AND IN VITRO].
Topics: Adenine; Aspartic Acid; Carbon Isotopes; DNA; DNA, Neoplasm; Dogs; Formates; Glucose; Glutamine; In Vitro Techniques; Metabolism; Neoplasms; Neoplasms, Experimental; Nucleic Acids; Pharmacology; Research; RNA; RNA, Neoplasm; Thymine | 1963 |
[CONDITION OF THE AMMONIA-GLUTAMINE-GLUTAMIC ACID SYSTEM IN THE RAT BRAIN DURING THE DEVELOPMENT OF M-1 SARCOMA].
Topics: Ammonia; Animals; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Glutamine; Metabolism; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental | 1964 |
S-Carbamylcysteine inhibition of protein synthesis by Ehrlich ascites tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cysteine; Glutamine; Humans; Neoplasms; Protein Biosynthesis; Proteins | 1962 |
An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice.
Topics: Amino Acid Substitution; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Collagen; Enzyme Activation; Extracellular Matrix; Female; Genetic Therapy; Genetic Vectors; Glutamine; Hepatocyte Growth Factor; Humans; Lentivirus; Methionine; Mice; Mice, Nude; Mitosis; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Protein Engineering; Protein-Tyrosine Kinases; Recombinant Proteins; Transduction, Genetic; Transplantation, Heterologous; Tumor Burden | 2004 |
Modulation of tumor induced angiogenesis in Ehrlich ascites tumor.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Proliferation; Diazooxonorleucine; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Mice; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Ovarian Neoplasms; Time Factors; Vascular Endothelial Growth Factor A | 2004 |
New strategies for management of oral mucositis in cancer patients.
Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Delivery Systems; Fibroblast Growth Factor 7; Glutamine; Growth Substances; Humans; Mouth Mucosa; Mucositis; Neoplasms; Practice Guidelines as Topic; Radiotherapy; Risk Factors | 2006 |
Acivicin: a new glutamine antagonist in clinical trials.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Dose-Response Relationship, Drug; Drug Evaluation; Female; Glutamine; Half-Life; Humans; Isoxazoles; Kinetics; Leukemia, Experimental; Liver Neoplasms, Experimental; Macaca mulatta; Male; Mice; Neoplasms; Oxazoles; Purines; Pyrimidines; Sarcoma, Experimental | 1984 |
[Effect of Litoralon therapy on the lymphocytotoxicity in patients with malignant tumors].
Topics: Antibody-Dependent Cell Cytotoxicity; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Glutamine; Humans; In Vitro Techniques; Neoplasms; Taurine | 1984 |
Phase I evaluation of AT-125 single dose every three weeks.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Central Nervous System; Drug Administration Schedule; Drug Evaluation; Glutamine; Humans; Isoxazoles; Middle Aged; Neoplasms; Oxazoles | 1984 |
The human hair follicle engages in glutaminolysis and aerobic glycolysis: implications for skin, splanchnic and neoplastic metabolism.
Topics: Adenosine Triphosphate; Aerobiosis; Cells, Cultured; Energy Metabolism; Fatty Acids; Glutamine; Glycolysis; Hair; Humans; Neoplasms; Skin; Viscera | 1994 |
Glutamine and glutamate in ascitic fluid of dogs.
Topics: Amino Acids; Animals; Ascites; Ascitic Fluid; Dog Diseases; Dogs; Glutamates; Glutamic Acid; Glutamine; Heart Failure; Hypoproteinemia; Liver Cirrhosis; Neoplasms; Peritonitis | 1993 |
Glutamine stability in biological tissues evaluated by fluorometric analysis.
Topics: Drug Stability; Glutamine; Humans; Hydrogen-Ion Concentration; Liver; Male; Neoplasms; Solutions; Temperature; Time Factors | 1993 |
Claude H. Organ, Jr. Honorary Lectureship. Glutamine, cancer, and its therapy.
Topics: Clinical Trials as Topic; Combined Modality Therapy; Glutamine; Glutathione; Humans; Immune System; Killer Cells, Natural; Neoplasms; Radiation Injuries | 1996 |
Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence.
Topics: Adipose Tissue; Adolescent; Adult; Aging; Animals; Cachexia; CD4 Lymphocyte Count; Citrulline; Cystine; Female; Glutamine; HIV Infections; Humans; Macaca; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Neoplasms; Simian Acquired Immunodeficiency Syndrome; Taurine | 1997 |
Should cancer patients with incurable disease receive parenteral or enteral nutritional support?
Topics: Arginine; Decision Making; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Parenteral Nutrition; Prognosis; Quality of Life; Terminal Care | 1998 |
Glutamine treatment of paclitaxel-induced myalgias and arthralgias.
Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Arthralgia; Female; Glutamine; Humans; Male; Middle Aged; Muscles; Neoplasms; Paclitaxel; Pain | 1998 |
Cooperative research group members question advertisement.
Topics: Advertising; Clinical Nursing Research; Clinical Trials as Topic; Glutamine; Humans; Interprofessional Relations; Neoplasms; Oncology Nursing; Periodicals as Topic; Truth Disclosure | 2001 |
Influence of glutamine and glycyl-glutamine on in vitro lymphocyte proliferation in children with solid tumors.
Topics: Adolescent; Cells, Cultured; Child; Child, Preschool; Dipeptides; Female; Glutamine; Humans; Immunity, Cellular; Infant; Lymphocyte Activation; Lymphocytes; Male; Neoplasms | 2001 |
L-glutamine.
Topics: Acquired Immunodeficiency Syndrome; Dietary Supplements; Gastrointestinal Diseases; Glutamine; Humans; Neoplasms; Wound Healing | 2001 |
Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7.
Topics: Adenylate Kinase; Animals; Aspartate Aminotransferases; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Glutamine; Glycolysis; Kidney; Models, Biological; Neoplasms; Nucleotides; Oncogene Protein p21(ras); Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Pyruvate Kinase; Rats; Serine; Transfection | 2001 |
[The effect of L-Glutamine and Shakuyaku-Kanzo-to for paclitaxel-induced myalgia/arthralgia].
Topics: Antineoplastic Agents, Phytogenic; Arthralgia; Drug Administration Schedule; Drug Combinations; Drugs, Chinese Herbal; Female; Glutamine; Glycyrrhiza; Humans; Muscle, Skeletal; Neoplasms; Paclitaxel; Paeonia; Pain; Quality of Life | 2002 |
Imaging of spontaneous canine tumours with ammonia and L-glutamine labeled with N-13.
Topics: Ammonia; Animals; Dog Diseases; Dogs; Female; Glutamine; Lymphoma, Non-Hodgkin; Male; Mesothelioma; Neoplasms; Nitrogen Radioisotopes; Radionuclide Imaging; Thoracic Neoplasms | 1977 |
Availability of glutamine from peptides and acetylglutamine for human tumor-cell cultures.
Topics: Breast Neoplasms; Cell Division; Dipeptides; DNA; Glutamine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Tumor Cells, Cultured | 1989 |
Immunosuppressive enzymes.
Topics: Animals; Antigens; Asparaginase; Asparagine; Encephalomyelitis, Autoimmune, Experimental; Erythrocytes; Glutamine; Graft vs Host Reaction; Hemocyanins; Hemolytic Plaque Technique; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Mice; Mitogens; Neoplasms; Sheep; Skin Tests; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous | 1973 |
Survey of two types of glutaminases in plasma of patients suffering from cancer & other diseases.
Topics: Adult; Chronic Disease; Female; Glutaminase; Glutamine; Humans; Male; Middle Aged; Neoplasms; Pregnancy; Transaminases | 1974 |
Sensitivity to L-asparaginase and amino acid metabolism.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium | 1970 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
[The glutamine levels in the serum of tumor patients].
Topics: Ammonia; Chromatography, Paper; Glutamine; Humans; Neoplasms | 1968 |
Amino acid levels following L-asparagine amidohydrolase (EC.3.5.1.1) therapy.
Topics: Amidohydrolases; Amino Acids; Asparaginase; Asparagine; Female; Glutamates; Glutamine; Humans; Male; Neoplasms | 1969 |