glutamine has been researched along with Anoxemia in 84 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (25.00) | 18.7374 |
| 1990's | 17 (20.24) | 18.2507 |
| 2000's | 7 (8.33) | 29.6817 |
| 2010's | 20 (23.81) | 24.3611 |
| 2020's | 19 (22.62) | 2.80 |
| Authors | Studies |
|---|---|
| Alam, K; Bastani, NE; Chowdhury, A; Grimolizzi, F; Kolan, S; Li, G; Skålhegg, BS; Wik, JA | 1 |
| Hu, M; Huang, P; Kong, B; Li, Y; Ling, S; Liu, H; Ma, Y | 1 |
| Drlica, K; Jiang, Q; Kurland, IJ; Qiu, Y; Shi, L; Subbian, S; Tyagi, S | 1 |
| He, QQ; Huang, J; Li, T; Liang, Y; Lu, P; Ou, W; Tang, K; Wu, W; Xie, M; Yang, M; Yu, H; Zhang, Y; Zhou, J; Zuo, Y | 1 |
| Germán-Acacio, JM; Gómez-Martín, D; Maravillas-Montero, JL; Mejía-Domínguez, NR; Páez-Franco, JC; Pérez-Fragoso, A; Ponce-de-León, A; Tamez-Torres, KM; Torres-Ruiz, J; Ulloa-Aguirre, A | 1 |
| Huerta, L; Martínez-Méndez, D; Villarreal, C | 1 |
| Barnes, S; Benavides, GA; Darley-Usmar, VM; Johnson, MS; Tian, R; Xing, D | 1 |
| Ahn, E; Ahn, T; Bang, S; Choi, J; Han, JM; Hwang, GS; Kim, K; Kim, Y; Lee, HS; Luo, E; Min, DS; Park, SJ; Sung, Y; Yoo, HC; Yu, YC | 1 |
| Antoniewicz, MR; Oates, EH | 1 |
| Jiang, S; Wang, X; Yu, Z; Zhang, L; Zhao, R; Zhou, X | 1 |
| Awrey, SJ; Brown, WS; Chafe, SC; Dedhar, S; Gerbec, ZJ; McDonald, PC; Parker, SJ; Venkateswaran, G | 1 |
| Chen, S; Hou, C; Lin, Q; Lin, S; Liu, W; Qiu, Q; Xiao, T; Xie, L; Yang, Y; Zong, Y | 1 |
| Al-Nawas, B; Bache, M; Bull, F; Eckert, AW; Grosse, I; Güttler, A; Kappler, M; Kaune, T; Kotrba, J; Krohn, K; Pabst, U; Porsch, M; Riemann, A; Rot, S; Schubert, J; Seliger, B; Taubert, H; Thews, O; Vordermark, D; Weinholdt, C; Wickenhauser, C | 1 |
| Gao, Y; Guo, Y; Liu, Y; Lu, F; Piao, Y; Tan, S; Tang, Y | 1 |
| Caris, AV; Tavares-Silva, E; Thomatieli-Santos, RV | 1 |
| Arts, M; Cramer, T; Heeren, RMA; Olde Damink, SW; Peter Neumann, U; Röth, A; Soons, Z; Wappler, J | 1 |
| Aragonés, J; Bouthelier, A | 1 |
| Arif, HM; Fu, M; Jin, Z; Shuang, T; Verma, R; Wang, R; Wondimu, E; Wu, L; Zhang, Q | 1 |
| Caris, AV; Dos Santos Quaresma, M; Lemos, VA; Souza, W; Thomatieli-Santos, RV | 1 |
| Akman, M; Belisario, DC; De Smaele, E; Donadelli, M; Kopecka, J; Pasino, M; Riganti, C | 1 |
| Johansson, ME; Mohlin, S; Munksgaard Thorén, M; Påhlman, S; Planck, M; Staaf, J; Vaapil, M | 1 |
| Barkhuizen, M; Cleutjens, JPM; Engelbertink, I; Gavilanes, AWD; Gussenhoven, R; Jellema, RK; Kramer, BW; Seehase, M; Steinbusch, HWM; van Dijck, FJP; van Mechelen, R; Zimmermann, LJ | 1 |
| Caris, AV; Lira, FS; Oyama, LM; Santos, SA; Silva, ET; Thomatieli-Santos, RV | 1 |
| Berthezène, P; Calvo, E; Dusetti, NJ; Guillaumond, F; Iovanna, JL; Lavaut, MN; Leca, J; Loncle, C; Olivares, O; Tomasini, R; Turrini, O; Vasseur, S; Vidal, N | 1 |
| Archer, SL; Fang, YH; Parikh, K; Piao, L; Ryan, JJ; Toth, PT | 1 |
| Forbes, NS; Kasinskas, RW; Venkatasubramanian, R | 1 |
| Niu, WN; Qiao, XJ; Shang, XY; Sun, R; Xu, CC; Xu, CL | 1 |
| Hankins, GD; Ramadoss, J; Sawant, OB; Washburn, SE; Wu, G | 1 |
| Corbet, C; Feron, O | 1 |
| Khairova, VR; Safarov, MI | 1 |
| Coelho, V; Dal-Cim, T; Lanznaster, D; Martins, WC; Poluceno, GG; Tasca, CI; Thomaz, DT; Vandresen-Filho, S | 1 |
| Bache, M; Eckert, AW; Grosse, I; Immel, UD; Kappler, M; Pabst, U; Rot, S; Schubert, J; Taubert, H; Vordermark, D; Weinholdt, C; Wichmann, H | 1 |
| Handrick, R; Jendrossek, V; Klein, D; Lüdemann, L; Matschke, J; Metzen, E; Riffkin, H; Shlomi, T; Stuschke, M | 1 |
| Brouwers-Vos, AZ; Günther, UL; Jaques, J; Koczula, KM; Pruis, M; Schuringa, JJ; Sontakke, P; Vellenga, E; Wierenga, AT | 1 |
| Liebenberg, L; Mathews, EH; Pelzer, R | 1 |
| Li, SZ; Liu, FY; Luo, YJ; Wang, GS; Yang, DZ; Zhou, QQ | 1 |
| Chiang, GG; Filipp, FV; Knutzen, CA; Osterman, AL; Richardson, AD; Ronai, ZA; Scott, DA; Smith, JW | 1 |
| Buck, LT; Dhiyebi, H; Duquette, S; Pamenter, ME; Sangha, N; Skelton, G; Smith, MD; Wilkie, MP | 1 |
| Feron, O; Polet, F | 1 |
| Kles, KA; Tappenden, KA | 1 |
| Bui, BV; Kalloniatis, M; Vingrys, AJ | 1 |
| Akisu, M; Baka, M; Huseyinov, A; Kultursay, N | 1 |
| FERDMAN, DL; SILAKOVA, AI | 1 |
| Gerich, FJ; Hepp, S; Müller, M | 1 |
| Bijlsma, PB; Koffeman, GI; Schoots, IG; van Gulik, TM | 1 |
| Fukuzawa, M; Soh, H; Wasa, M | 1 |
| Lopes-Vieira, O; Walker, B; Williamson, DH | 1 |
| Koudelová, J; Trojan, S | 1 |
| Ivanov, VE; Kapelko, VI; Pisarenko, OI; Smirnov, VN; Solomatina, ES; Studneva, IM | 1 |
| Block, ER; Su, Y | 1 |
| Brusilow, SW; Hirata, T; Koehler, RC; Traystman, RJ | 1 |
| Hertz, L; Huang, R | 3 |
| Aquila, WJ; Donnelly, DF; During, MJ; Haddad, GG; Perry, VL; Young, RS | 1 |
| Aas, JE; Berg-Johnsen, J; Hegstad, E; Laake, JH; Langmoen, IA; Ottersen, OP | 1 |
| Curzon, G; Obrenovitch, TP; Richards, DA; Symon, L; Ueda, Y; Urenjak, J | 1 |
| Bigard, AX; Douce, P; Guezennec, CY; Lienhard, F; Merino, D | 1 |
| Hadjiconstantinou, M; Krajnc, D; Neff, NH | 1 |
| Honda, Y; Kimura, H; Kobayashi, T; Kuriyama, T; Masuda, A; Masuyama, S; Nishino, T; Tani, H | 2 |
| Dixon, RM; Griffin, JL; Matthews, PM; Radda, GK; Rae, C | 1 |
| Fassnacht, D; Pörtner, R | 1 |
| Bailey, DM; Castell, LM; Davies, B; Newsholme, EA | 1 |
| Leusen, I; Van Leuven, F; Weyne, J | 2 |
| Goodman, MN; Lowenstein, JM | 1 |
| Ostrovskaia, RU; Safronova, MI; Tsybina, NM; Zubovskaia, AM | 1 |
| Erecińska, M; Silver, IA | 1 |
| Juanes, MC; Martín-Barrientos, J; Medina, JM; Vicario, C | 1 |
| Krützfeldt, A; Mertens, S; Noll, T; Piper, HM; Spahr, R | 1 |
| Lisý, V; Stastný, F; Tomásová, H; Trojan, S | 1 |
| Choi, DW; Goldberg, MP; Monyer, H | 1 |
| Changaris, DG; Rigor, BM; Schurr, A | 1 |
| Alonso, S; Jofre, R; Junco, E; Lemieux, G; Perez, R; Rengel, M; Valderrabano, F; Vinay, P | 1 |
| Menis, LS; Tsvelev, IuV | 1 |
| Fixter, LM; Phizackerley, PJ | 1 |
| Baev, VI; Brattseva, SA; Korostovtseva, NV; Valeeva, GA | 1 |
| Holmin, T; Siesjö, BK | 1 |
| Pfleiderer, T | 1 |
| Elliott, KA; Yoshino, Y | 1 |
| Aoki, VS; Davidson, MB | 1 |
| Arnfred, T; Hertz, L | 1 |
| Okunev, VN; Prokhorenko, LG | 1 |
7 review(s) available for glutamine and Anoxemia
| Article | Year |
|---|---|
Role of the HIF oxygen sensing pathway in cell defense and proliferation through the control of amino acid metabolism.
Topics: Amino Acids; Animals; Cell Proliferation; Citric Acid Cycle; Collagen; Glutamine; Glutathione; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Oxidation-Reduction; Oxidative Stress; Oxygen; Signal Transduction | 2020 |
The Possible Importance of Glutamine Supplementation to Mood and Cognition in Hypoxia from High Altitude.
Topics: Affect; Altitude; Cognition; Dietary Supplements; Glutamine; Humans; Hypoxia | 2020 |
Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance.
Topics: Amino Acids; Animals; Citric Acid Cycle; Dimerization; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glucose; Glutamine; Humans; Hypoxia; Lactic Acid; Mice; Mitochondria; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen; Phenotype; Reactive Oxygen Species; Tumor Microenvironment | 2020 |
Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
Topics: Acetates; Acetyl Coenzyme A; Cell Line, Tumor; Citrates; Citric Acid Cycle; Glucose; Glutamine; Humans; Hypoxia; Ketoglutaric Acids; Lipogenesis; Neoplasms | 2015 |
Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force.
Topics: Angiogenesis Inhibitors; Endothelial Cells; Endothelium, Vascular; Glucose; Glutamine; Glycolysis; Humans; Hypoxia; Lactic Acid; Neoplasms; Neovascularization, Pathologic; Oxidation-Reduction | 2013 |
Metabolism and role of glutamate in mammalian brain.
Topics: Animals; Astrocytes; Biological Transport; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glutamine; Glutathione; Hypoglycemia; Hypoxia; Mammals; Neurons; Synaptosomes | 1990 |
[Hepatic coma--clinical aspects and biochemistry].
Topics: Alkalosis; Ammonia; Glucose; Glutamine; Hepatic Encephalopathy; Humans; Hydrogen-Ion Concentration; Hypokalemia; Hypoxia; Kidney; Liver; Liver Function Tests | 1968 |
3 trial(s) available for glutamine and Anoxemia
| Article | Year |
|---|---|
Effects of carbohydrate and glutamine supplementation on cytokine production by monocytes after exercise in hypoxia: A crossover, randomized, double-blind pilot study.
Topics: Adult; Cross-Over Studies; Cytokines; Dietary Carbohydrates; Dietary Supplements; Double-Blind Method; Exercise; Glutamine; Healthy Volunteers; Humans; Hypoxia; Male; Monocytes; Oxygen Consumption; Physical Exertion; Pilot Projects | 2020 |
Effect of prior O2 breathing on ventilatory response to sustained isocapnic hypoxia in adult humans.
Topics: Administration, Inhalation; Adult; Carbon Dioxide; Female; Glutamic Acid; Glutamine; Hormones; Humans; Hypoxia; Male; Neurotransmitter Agents; Oxygen; Plasma; Respiratory Function Tests; Respiratory Mechanics | 1996 |
Continuous and intermittent exposure to the hypoxia of altitude: implications for glutamine metabolism and exercise performance.
Topics: Adaptation, Physiological; Altitude; Analysis of Variance; Double-Blind Method; Exercise; Glutamine; Humans; Hypoxia; Immunosuppression Therapy; Inspiratory Capacity; Oxygen; Partial Pressure; Physical Endurance; South Africa; Statistics, Nonparametric; United Kingdom | 2000 |
74 other study(ies) available for glutamine and Anoxemia
| Article | Year |
|---|---|
Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4+ T-cell proliferation and glycolytic activity under hypoxia and normoxia.
Topics: Amino Acids; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Proliferation; Glucose; Glutamic Acid; Glutaminase; Glutamine; Humans; Hypoxia; Oxygen; Pyruvic Acid | 2022 |
Loss of Heterozygosity for
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Glutamine; Humans; Hypoxia; Loss of Heterozygosity; Mice; Pancreatic Neoplasms; Phenotype; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras) | 2022 |
Glutamine Is Required for M1-like Polarization of Macrophages in Response to Mycobacterium tuberculosis Infection.
Topics: Aspartic Acid; Carbon; Glucose; Glutamine; Glycolysis; Humans; Hypoxia; Macrophages; Mycobacterium tuberculosis; Nitrogen; Tuberculosis | 2022 |
Hypoxia-triggered O-GlcNAcylation in the brain drives the glutamate-glutamine cycle and reduces sensitivity to sevoflurane in mice.
Topics: Acetylglucosamine; Anesthetics, General; Animals; Brain; Diazooxonorleucine; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hypoxia; Mice; Oxygen; Sevoflurane | 2022 |
Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology.
Topics: Amino Acids; COVID-19; Cystine; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Homeostasis; Humans; Hypoxia; Male; Oxidation-Reduction; Oxygen; Proline; Reactive Oxygen Species; SARS-CoV-2 | 2022 |
Modeling the effect of environmental cytokines, nutrient conditions and hypoxia on CD4
Topics: Cell Differentiation; Cytokines; Glutamine; Humans; Hypoxia; Interleukin-4; Lymphocyte Activation; Nutrients; Oxygen; Th1 Cells; Th2 Cells; Tryptophan | 2022 |
Glutamine-dependent effects of nitric oxide on cancer cells subjected to hypoxia-reoxygenation.
Topics: Energy Metabolism; Glutamine; Humans; Hypoxia; Ketoglutaric Acids; Neoplasms; Nitric Oxide | 2023 |
Enhanced Glutaminolysis Drives Hypoxia-Induced Chemoresistance in Pancreatic Cancer.
Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Glutamine; Humans; Hypoxia; Pancreatic Neoplasms | 2023 |
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Diabetes Mellitus, Type 2; Glutamine; Hypoxia; Lipid Metabolism; Metabolic Flux Analysis; Mice; Obesity | 2023 |
Metabolites and gene expression in the myocardium of fasting rats in an acute hypoxic environment.
Topics: Animals; Fasting; Gene Expression; Glutamine; Hypoxia; Lipids; Myocardium; Rats; Rats, Sprague-Dawley | 2023 |
A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells.
Topics: Amino Acid Transport System ASC; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line, Tumor; Ferroptosis; Glutamine; Humans; Hypoxia; Minor Histocompatibility Antigens | 2023 |
Serum Metabolomic Profile in Hypoxia-Induced Pulmonary Hypertension Mice after C75 Treatment.
Topics: Animals; Child; China; Glutamine; Humans; Hypertension, Pulmonary; Hypoxia; Lipids; Mice; Polyamines | 2023 |
Causes and Consequences of A Glutamine Induced Normoxic HIF1 Activity for the Tumor Metabolism.
Topics: Acetylation; Ascorbic Acid; Carbonic Anhydrase IX; Cell Line, Tumor; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; High-Throughput Nucleotide Sequencing; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Protein Stability; RNA, Small Interfering | 2019 |
Metabolomic changes of blood plasma associated with two phases of rat OIR.
Topics: Animals; Animals, Newborn; Biomarkers; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamine; Hyperoxia; Hypoxia; Metabolome; Metabolomics; Ornithine; Oxidative Stress; Oxygen; Proline; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinopathy of Prematurity | 2020 |
Glutamine deprivation counteracts hypoxia-induced chemoresistance.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Energy Metabolism; Female; Glutamine; Humans; Hypoxia; Male; Middle Aged; Oxygen Consumption; Proto-Oncogene Proteins c-myc; Tumor Microenvironment | 2020 |
H
Topics: Adenosine Triphosphate; Animals; Chickens; Electron Transport; Energy Metabolism; Erythrocytes; Female; Glucose; Glutamine; Hydrogen Sulfide; Hypoxia; Mitochondria; Succinic Acid; Sulfurtransferases | 2020 |
Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells.
Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Female; Gene Amplification; Gene Expression; Gene Knockdown Techniques; Genes, myc; Glutamine; Glycolysis; Heterografts; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Models, Biological; Small Cell Lung Carcinoma | 2017 |
The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb.
Topics: Anesthetics; Animals; Animals, Newborn; Brain Mapping; Dopamine; Dopaminergic Neurons; Female; Glutamine; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Inflammation; Isoflurane; Male; Mesencephalon; Microglia; Neurotransmitter Agents; Phosphorylation; Propofol; Sheep; Substantia Nigra; Synaptic Transmission; tau Proteins; Tyrosine 3-Monooxygenase; Umbilical Cord | 2018 |
Effect of moderate exercise under hypoxia on Th1/Th2 cytokine balance.
Topics: Adult; Altitude Sickness; Cytokines; Exercise; Exercise Test; Glutamine; Humans; Hypoxia; Immunomodulation; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-10; Interleukin-2; Interleukin-4; Interleukin-6; Male; Oxygen Consumption; Tumor Necrosis Factor-alpha | 2019 |
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glutamine; Glycolysis; Hexosamines; Humans; Hypoxia; Lactic Acid; Male; Metabolic Networks and Pathways; Mice; Mice, Nude; Mice, Transgenic; Models, Biological; Pancreatic Neoplasms; Transplantation, Heterologous | 2013 |
Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Diazooxonorleucine; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Glucose; Glutamine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Models, Biological; Oxidation-Reduction; Proto-Oncogene Proteins c-myc; Rats | 2013 |
Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypoxia; Kinetics; Lactic Acid; Microscopy, Fluorescence; Models, Theoretical | 2014 |
Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment.
Topics: Animals; Bacteria; Cytokines; Cytoprotection; Disease Models, Animal; Glutamine; Hypoxia; Inflammation Mediators; Intestinal Mucosa; Intestines; Male; Malondialdehyde; Myeloid Differentiation Factor 88; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Time Factors; Toll-Like Receptor 4; Transcription Factor RelA | 2014 |
Effects of L-glutamine supplementation on maternal and fetal hemodynamics in gestating ewes exposed to alcohol.
Topics: Alcohol Drinking; Alcoholic Beverages; Animals; Binge Drinking; Blood Pressure; Brain; Dietary Supplements; Ethanol; Female; Fetal Blood; Fetus; Glutamine; Heart Rate; Hemodynamics; Hypercapnia; Hypoxia; Pregnancy; Regional Blood Flow; Sheep; Uterus | 2014 |
[DYNAMICS OF GLUTAMINE SYNTHASE ACTIVITY IN RAT BRAIN IN PRENATAL HYPOXIA MODEL].
Topics: Ammonia; Animals; Apoptosis; Brain Chemistry; Cerebellum; Cerebral Cortex; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hypothalamus; Hypoxia; Maternal Exposure; Medulla Oblongata; Organogenesis; Oxygen; Rats; Rats, Wistar; Stress, Physiological | 2015 |
Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glutamate-Ammonia Ligase; Glutamine; Guanosine; Hippocampus; Hypoxia; In Vitro Techniques; Male; Rats; Rats, Wistar; Tritium | 2016 |
Normoxic accumulation of HIF1α is associated with glutaminolysis.
Topics: Ammonia; Blotting, Western; Carbonic Anhydrase IX; Cell Line, Tumor; Cell Proliferation; Glutamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger | 2017 |
Targeted Inhibition of Glutamine-Dependent Glutathione Metabolism Overcomes Death Resistance Induced by Chronic Cycling Hypoxia.
Topics: Adaptation, Biological; Animals; Antioxidants; Aspartate Aminotransferase, Cytoplasmic; Cell Death; Cell Hypoxia; Cell Line, Tumor; Dioxolanes; Gene Expression Regulation, Neoplastic; Glutamine; Glutathione; Humans; Hypoxia; Mice; Oxidation-Reduction; Oxidative Stress; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2016 |
Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation.
Topics: Antigens, CD34; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cells, Cultured; Fetal Blood; Fusion Proteins, bcr-abl; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Hypoxia; Immunoenzyme Techniques; Infant, Newborn; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Magnetic Resonance Spectroscopy; Metabolomics; Neoplasm Proteins; Oxidative Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2016 |
High-glycolytic cancers and their interplay with the body's glucose demand and supply cycle.
Topics: Animals; Blood Glucose; Brain; Cell Line, Tumor; Fatty Acids; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; Humans; Hypoxia; Immune System; Lactates; Models, Biological; Neoplasms; Treatment Outcome | 2011 |
Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation under high-altitude hypoxic environment.
Topics: Altitude; Amine Oxidase (Copper-Containing); Animals; Apoptosis; Bacterial Translocation; Disease Models, Animal; Endotoxins; Glutamine; Hypoxia; In Situ Nick-End Labeling; Intestinal Diseases; Intestinal Mucosa; Intestines; Lymph Nodes; Male; Malondialdehyde; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spleen; Starvation; Superoxide Dismutase; Time Factors | 2011 |
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.
Topics: Cell Line, Tumor; Citric Acid Cycle; Fermentation; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Glycolysis; Humans; Hypoxia; Ketoglutaric Acids; Lactic Acid; Melanocytes; Melanoma; Models, Biological; Skin Neoplasms | 2011 |
The relationship between NMDA receptor function and the high ammonia tolerance of anoxia-tolerant goldfish.
Topics: Ammonia; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamine; Goldfish; Hypoxia; Nitrogen; Oncorhynchus mykiss; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Toxicity Tests, Acute; Urea; Water Pollutants, Chemical | 2011 |
Hypoxia differentially regulates nutrient transport in rat jejunum regardless of luminal nutrient present.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Transport System ASC; Animals; Biological Transport; Glucose; Glutamine; Hypoxia; Intestinal Absorption; Jejunum; Male; Mannitol; Membrane Glycoproteins; Minor Histocompatibility Antigens; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Glucose Transporter 1 | 2002 |
The contribution of glycolytic and oxidative pathways to retinal photoreceptor function.
Topics: Aerobiosis; Anaerobiosis; Animals; Dark Adaptation; Drug Combinations; Electroretinography; Glucose; Glutamine; Glycolysis; Hypoglycemia; Hypoxia; Lactic Acid; Oxidative Stress; Oxygen; Photoreceptor Cells, Vertebrate; Rats; Rats, Long-Evans; Vision, Ocular; Vitreous Body | 2003 |
The role of dietary supplementation with L-glutamine in inflammatory mediator release and intestinal injury in hypoxia/reoxygenation-induced experimental necrotizing enterocolitis.
Topics: Administration, Oral; Animals; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocolitis, Necrotizing; Glutamine; Hypoxia; Intestinal Mucosa; Intestines; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Random Allocation; Tumor Necrosis Factor-alpha | 2003 |
[Ammonium, glutamine and glutamic acid in the skeletal muscles in hypoxemia].
Topics: Ammonium Compounds; Central Nervous System; Glutamic Acid; Glutamine; Hypoxia; Muscle, Skeletal; Muscles; Nervous System; Nervous System Physiological Phenomena | 1951 |
Sulfhydryl oxidation reduces hippocampal susceptibility to hypoxia-induced spreading depression by activating BK channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aniline Compounds; Animals; Calcium; Charybdotoxin; Cortical Spreading Depression; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamine; Hippocampus; Hypoxia; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Neurons; Nickel; Oxidation-Reduction; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Tolbutamide; Valine; Xanthenes | 2005 |
Hypoxia/reoxygenation impairs glucose absorption and cAMP-mediated secretion more profoundly than glutamine absorption and Ca2+/PKC-mediated secretion in rat ileum in vitro.
Topics: Absorption; Animals; Cyclic AMP; Electrophysiology; Glucose; Glutamine; Hypoxia; Ileum; Ischemia; Male; Protein Kinases; Rats; Rats, Wistar; Reperfusion Injury | 2006 |
Hypoxia upregulates amino acid transport in a human neuroblastoma cell line.
Topics: Amino Acids; Biological Transport; Cell Hypoxia; Cycloheximide; Dactinomycin; Glutamic Acid; Glutamine; Humans; Hypoxia; Leucine; Neuroblastoma; Protein Synthesis Inhibitors; Tumor Cells, Cultured; Up-Regulation | 2007 |
Concentrations of free glucogenic amino acids in livers of rats subjected to various metabolic stresses.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Gluconeogenesis; Glutamates; Glutamine; Hypoxia; Insulin; Liver; Male; Phlorhizin; Rats; Serine; Starvation; Threonine; Transaminases | 1967 |
Effect of single and repeated aerogenic hypoxia on the content of amino acids in the rat brain.
Topics: Age Factors; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hypoxia; Male; Rats | 1980 |
Effect of exogenous amino acids on the contractility and nitrogenous metabolism of anoxic heart.
Topics: Alanine; Ammonia; Animals; Arginine; Glutamates; Glutamine; Hypoxia; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains | 1983 |
Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Citrulline; Culture Techniques; Endothelium, Vascular; Glutamine; Hypoxia; Pulmonary Artery; Swine | 1995 |
Preservation of cerebral blood flow responses to hypoxia and arterial pressure alterations in hyperammonemic rats.
Topics: Ammonia; Animals; Blood Pressure; Brain; Cerebrovascular Circulation; Glutamine; Hemorrhage; Homeostasis; Hypertension; Hypoxia; Male; Phenylephrine; Rats; Rats, Wistar | 1995 |
Neuroprotective effect of phenylsuccinate, an inhibitor of cytosolic glutamate formation from glutamine, under anoxic conditions but not during exposure to exogenous glutamate.
Topics: Animals; Cell Death; Cerebellum; Glutamic Acid; Glutamine; Hypoxia; L-Lactate Dehydrogenase; Mice; Succinates | 1995 |
Effect of anoxia on glutamate formation from glutamine in cultured neurons: dependence on neuronal subtype.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Extracellular Space; Glutamic Acid; Glutamine; Granulocytes; Hypoxia; Intracellular Membranes; Mice; Neurons | 1994 |
Effect of anoxia on excitatory amino acids in brain slices of rats and turtles: in vitro microdialysis.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Stem; Dialysis; Glutamates; Glutamic Acid; Glutamine; Glycine; Hypoxia; Rats; Rats, Sprague-Dawley; Time Factors; Turtles | 1993 |
Redistribution of glutamate and glutamine in slices of human neocortex exposed to combined hypoxia and glucose deprivation in vitro.
Topics: Brain Ischemia; Cerebral Cortex; Glucose; Glutamates; Glutamic Acid; Glutamine; Humans; Hypoxia; Immunohistochemistry; In Vitro Techniques; Microscopy, Electron; Tissue Distribution | 1993 |
Extracellular neuroactive amino acids in the rat striatum during ischaemia: comparison between penumbral conditions and ischaemia with sustained anoxic depolarisation.
Topics: Alanine; Amino Acids; Animals; Brain Ischemia; Corpus Striatum; Dialysis; Electroencephalography; Electrophysiology; Extracellular Space; Glutamine; Glycine; Hypoxia; Male; Nervous System Physiological Phenomena; Rats; Rats, Sprague-Dawley | 1993 |
Potentiation by K+ of anoxic release of newly synthesized neuronal glutamate.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Extracellular Space; Glutamic Acid; Glutamine; Hypoxia; L-Lactate Dehydrogenase; Mice; Neurons; Potassium | 1995 |
Changes in dietary protein intake fail to prevent decrease in muscle growth induced by severe hypoxia in rats.
Topics: Altitude; Animals; Body Weight; Diet; Dietary Proteins; Eating; Glutamic Acid; Glutamine; Histocytochemistry; Hypoxia; Liver Glycogen; Male; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; Organ Size; Rats; Rats, Wistar | 1996 |
Glutamate, glutamine and glutamine synthetase in the neonatal rat brain following hypoxia.
Topics: Animals; Animals, Newborn; Brain; Corpus Striatum; Female; Frontal Lobe; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hippocampus; Hypoxia; Pregnancy; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Augmented ventilatory response to sustained normocapnic hypoxia following 100% O2 breathing in humans.
Topics: beta-Endorphin; Catecholamines; Glutamine; Humans; Hyperventilation; Hypoventilation; Hypoxia; Male; Neurotransmitter Agents; Oxygen; Respiration; Single-Blind Method | 1996 |
Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia?
Topics: Alanine; Animals; Brain; Carbon; Excitatory Amino Acids; Glutamic Acid; Glutamine; Guinea Pigs; Hypoxia; In Vitro Techniques; Intracellular Membranes; Osmolar Concentration; Perfusion; Pyruvic Acid; Reference Values; Substrate Specificity | 1998 |
Experimental and theoretical considerations on oxygen supply for animal cell growth in fixed-bed reactors.
Topics: Animals; Bioreactors; Biotechnology; Glucose; Glutamine; Hybridomas; Hypoxia; Kinetics; Mice; Models, Theoretical; Oxygen; Time Factors; Tumor Cells, Cultured | 1999 |
Organic acids in the brain in hypoxemia.
Topics: Ammonia; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hypoxia; Ketoglutaric Acids; Lactates; Rats | 1976 |
The purine nucleotide cycle. Studies of ammonia production by skeletal muscle in situ and in perfused preparations.
Topics: Adenosine Monophosphate; Alanine; Ammonia; Animals; Citrates; Cyanides; Epinephrine; Glutamine; Glycolysis; Hypoxanthines; Hypoxia; Inosine Nucleotides; Malates; Male; Muscles; Perfusion; Physical Exertion; Purine Nucleotides; Rats; Succinates | 1977 |
Brain amino acids in conscious rats in chronic normocapnic and hypocapnic hypoxemia.
Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Brain Chemistry; Carbon Dioxide; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hypoxia; Ketoglutaric Acids; Lactates; Rats | 1977 |
[Effect of succinic semialdehyde on nitrogen metabolism of animal brain tissue during hypoxia].
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hypoxia; Mice; Succinates | 1976 |
Effect of postnatal hypoxia on ammonia metabolism during the early neonatal period in the rat.
Topics: Allantoin; Ammonia; Animals; Animals, Newborn; Blood Gas Analysis; Glutamates; Glutamine; Hypoxia; Lactates; Rats; Rats, Inbred Strains; Urea; Xanthines | 1990 |
Energetic response of coronary endothelial cells to hypoxia.
Topics: Animals; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Energy Metabolism; Glucose; Glutamine; Hypoxia; Oxygen Consumption; Palmitic Acid; Palmitic Acids | 1990 |
Effects of short-term and prolonged aerogenic hypoxia on gamma-glutamyl transpeptidase activity in the brain, liver, and biological fluids of young rats.
Topics: Altitude; Animals; Aspartic Acid; Body Fluids; Brain; Female; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutamine; Hypoxia; Liver; Male; Rats; Rats, Inbred Strains | 1985 |
Hypoxic neuronal injury in vitro depends on extracellular glutamine.
Topics: Anaerobiosis; Animals; Cells, Cultured; Cerebral Cortex; Fetus; Glutamine; Hypoxia; L-Lactate Dehydrogenase; Mice; Neurons; Reference Values | 1988 |
Glutamine protects neuronal function against cerebral hypoxia: a study using the in vitro hippocampal slice preparation.
Topics: Animals; Brain Diseases; Glutamine; Hippocampus; Hypoxia; In Vitro Techniques; Male; Neurons; Rats; Synapses | 1987 |
Renal ammoniagenesis during acute hypoxic lactic acidosis in the dog.
Topics: Acidosis; Adenosine Triphosphate; Ammonia; Animals; Dogs; Glutamine; Hypoxia; Kidney; Lactates; Oxygen Consumption | 1985 |
[Use of glutamine for increasing the resistance to hypoxia of the intra-uterine fetus and for intensifying labor].
Topics: Animals; Female; Fetal Diseases; Fetus; Glutamine; Humans; Hypoxia; Isoenzymes; L-Lactate Dehydrogenase; Labor, Induced; Myocardium; Pregnancy; Rabbits; Rats | 1972 |
Effects of anoxia in vitro on cellular respiration of brain cortex.
Topics: Age Factors; Amino Acids; Anaerobiosis; Animals; Aspartic Acid; Cerebral Cortex; Chromatography, Gel; Female; Glucose; Glutamine; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Male; Oxaloacetates; Oxygen Consumption; Rats; Temperature; Time Factors; Tissue Extracts; Water | 1973 |
[Ammonia and glutamine concentrations in the brain of mice subjected to chilling, hypercapnia and hypoxia].
Topics: Adaptation, Physiological; Ammonia; Animals; Brain; Brain Chemistry; Cerebellum; Glutamine; Hypercapnia; Hypothermia, Induced; Hypoxia; Male; Mice; Recurrence; Time Factors | 1973 |
Influence of hypoxia on cerebral energy state in rats with porta-caval anastomosis.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Blood Glucose; Brain; Creatine; Glucose; Glucosephosphates; Glutamates; Glutamine; Hydrogen-Ion Concentration; Hypoxia; Lactates; Malates; Male; Oxygen; Phosphocreatine; Portacaval Shunt, Surgical; Pyruvates; Rats; Temperature; Time Factors | 1974 |
Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes; Depression, Chemical; Glucose; Glutamates; Glutamine; Glycolates; Hypoxia; Injections, Intravenous; Lactates; Male; Metabolism; Methods; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stimulation, Chemical; Time Factors | 1970 |
Fasting glucose homeostasis in rats after chronic exposure to hypoxia.
Topics: Altitude; Amino Acids; Animals; Blood Glucose; Carboxy-Lyases; Erythrocytes; Fasting; Gluconeogenesis; Glutamine; Glycerol; Glycogen; Homeostasis; Hypoxia; Insulin; Lactates; Liver; Male; Muscles; Pyruvate Kinase; Rats | 1970 |
Effects of potassium and glutamate on brain cortex slices: uptake and release of glutamic and other amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Carbon Isotopes; Cerebral Cortex; Chromatography, Paper; Glutamates; Glutamine; Hypoxia; In Vitro Techniques; Leucine; Lysine; Potassium; Rats; Tritium; Water-Electrolyte Balance | 1971 |
[Some peculiarities of nitrogen metabolism in the rat brain on detonating gas poisoning].
Topics: Adenosine Triphosphate; Aminobutyrates; Ammonia; Animals; Brain; Carbon Monoxide Poisoning; Explosions; Gas Poisoning; Glutamates; Glutamine; Hypoxia; Nitrogen; Rats | 1966 |