glutamine has been researched along with Aging in 189 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (25.40) | 18.7374 |
| 1990's | 51 (26.98) | 18.2507 |
| 2000's | 36 (19.05) | 29.6817 |
| 2010's | 43 (22.75) | 24.3611 |
| 2020's | 11 (5.82) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
| Bisbach, CM; Campbell, MD; Cleghorn, WM; Hass, DT; Hurley, JB; Jankowski, CSR; Linton, JD; Marcinek, DJ; Rabinovitch, PS; Robbings, BM; Rountree, AM; Sadilek, M; Sweet, IR; Sweetwyne, MT; Tsantilas, KA; Valencia, AP; Whitson, JA; Zhang, H | 1 |
| Hu, D; Hu, L; Jiao, D; Li, G; Li, X; Li, Z; Liu, S; Qi, L; Wu, H; Zhao, C | 1 |
| Luo, S; Shi, Y; Tan, H; Weng, J; Xu, M; Xu, S; Yue, T | 1 |
| Česnaitienė, VJ; Drozdova-Statkevičienė, M; Dudonienė, V; Gleiznienė, R; Himmelreich, U; Katkutė, G; Kušleikienė, S; Levin, O; Masiulis, N; Pääsuke, M; Sheoran, S; Valatkevičienė, K; Vints, WAJ; Ziv, G | 1 |
| Chen, C; Du, G; Gao, L; Li, M; Qin, X; Yang, L; Zhou, Y | 1 |
| Al-Harthi, L; Gonzalez, H; Podany, A; Wallace, J | 1 |
| Sandireddy, R; Singh, BK; Tikno, K; Tripathi, M; Yen, PM; Zhou, J | 1 |
| Amorim, R; Berardi, E; Cappellesso, F; Carmeliet, P; Carobbio, S; De Bock, K; Di Matteo, M; Eelen, G; Ghesquière, B; Ho, PC; Maechler, P; Mazzone, M; Rincon, MY; Sandri, M; Serneels, J; Shang, M; Virga, F | 1 |
| Delgado, TC; Martínez-Chantar, ML; Simón, J | 1 |
| Nikolova, S; Stark, CEL; Stark, SM | 1 |
| Basu, A; Bloch, W; Geiger, H; Kochanek, S; Krug, L; Maity, P; Meyer, P; Scharffetter-Kochanek, K; Singh, K; Treiber, N; Vander Beken, S; Wlaschek, M | 1 |
| Romanov, GA; Sukhoverov, VS | 1 |
| Asch, RH; Lindquist, DM; McNamara, RK; Schurdak, JD | 1 |
| Drulis-Fajdasz, D; Gizak, A; Rakus, D; Wiśniewski, JR; Wójtowicz, T | 1 |
| Cao, P; Fang, Y; Huang, Y; Lyu, J; Shen, Y; Zhang, J | 1 |
| Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M | 1 |
| Ge, R; Greenway, K; Laule, C; MacMillan, EL; Sporn, L; Vila-Rodriguez, F | 1 |
| Bolo, NR; Fried, PJ; Pascual-Leone, A | 1 |
| Gallinat, J; Hädel, S; Rapp, M; Schubert, F; Wirth, C | 1 |
| Aussel, C; Cynober, L; Deutz, NE; Jourdan, M | 1 |
| Coe, CL; Glei, DA; Goldman, N; Holmes, E; Lewis, M; Nicholson, JK; Ryff, CD; Seeman, TE; Spagou, K; Swann, JR; Weinstein, M | 1 |
| Beaufrère, AM; Meynial-Denis, D; Mignon, M; Patureau Mirand, P | 1 |
| Biolo, G; Cederholm, T; Muscaritoli, M | 1 |
| Coman, D; Hyder, F; Jiang, L; Lin, AL; Rothman, DL | 1 |
| Abdel-Aziz, K; Altmann, DR; Ciccarelli, O; Solanky, BS; Thompson, AJ; Wheeler-Kingshott, CA; Yiannakas, MC | 1 |
| Beaufrère, AM; Buffière, C; Cynober, L; Marceau, G; Meydinal-Denis, D; Neveux, N; Patureau Mirand, P; Sapin, V | 1 |
| Kumar, S; Lombard, DB | 1 |
| Cohen-Gilbert, JE; Crowley, DJ; Jensen, JE; Rosso, IM; Silveri, MM; Sneider, JT | 1 |
| Gong, QY; Quan, H; Sun, HQ; Tan, QY; Tan, ZJ; Xing, HY; Yang, ZY; Yue, Q | 1 |
| Mostoslavsky, R; Sebastián, C | 1 |
| Calhoun, D; Dudenbostel, T; Ellis, AC; Gower, B; Patterson, M | 1 |
| Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC | 1 |
| Blennow, K; Bruno, D; Hashimoto, K; Marmar, CR; Nierenberg, J; Pomara, N; Zetterberg, H | 1 |
| Meynial-Denis, D | 2 |
| Achim, CL; Jeste, DV; Kesby, JP; Kim, JJ; Kisseleva, T; Semenova, S; Soontornniyomkij, B; Soontornniyomkij, V | 1 |
| Fu, X; Guan, M; Huang, T; Liu, Q; Liu, R; Lu, WW; Wu, C; Yang, M; Yao, D | 1 |
| Friedrich, MG; Hancock, SE; Raftery, MJ; Truscott, RJ | 1 |
| Chen, H; Chiappelli, J; Du, X; Gaston, FE; Hong, LE; Kochunov, P; Korenic, SA; McMahon, RP; Ndubuizu, N; Rowland, LM; Savransky, A; Wang, DJ; Wijtenburg, SA; Wright, SN | 1 |
| Kanamatsu, T; Kohsaka, S; Koshimoto, M; Nakajima, K | 1 |
| Huang, D; Liu, D; Ni, H; Qian, T; Shrestha, S; Yin, J | 1 |
| Chang, CH; Ho, CT; Liao, VH | 1 |
| Bu, L; He, J; Hu, L; Jiang, H; Jin, Y; Kong, X; Lu, Y; Miao, A; Shi, X; Shi, Y | 1 |
| Barker, PB; Bibat, G; Farage, L; Horská, A; Kaufmann, WE; Nagae, LM; Naidu, S | 1 |
| Coelho, ZC; de Vasconcelos, PR; de Vasconcelos, RC; Fechine, FV; Galera, SC; Teixeira, MJ | 1 |
| Battu, CE; de Assis, AM; Farina, M; Gonçalves, CA; Hansen, F; Hoefel, AL; Longoni, A; Perry, ML; Rieger, DK; Schmidt, B; Sordi, F; Souza, DO | 1 |
| Hains, PG; Truscott, RJ | 1 |
| Mattsson, P; Raininko, R | 1 |
| Arnaud, E; Cartoni, R; Chrast, R; Courvoisier, DS; Martinou, JC; Médard, JJ; Poirot, O | 1 |
| Calzia, D; Morelli, A; Panfoli, I; Ravera, S | 1 |
| Back, K; Kang, K; Kim, YS; Kweon, SJ; Lee, K; Lee, S; Park, S | 1 |
| Behar, KL; De Feyter, HM; de Graaf, RA; Mason, GF; Rothman, DL | 1 |
| Hooi, MY; Raftery, MJ; Truscott, RJ | 1 |
| Beaufrère, AM; Bielicki, G; Meynial-Denis, D; Mignon, M; Mirand, PP; Renou, JP | 1 |
| Collins, MJ; Hollund, H; Soressi, M; van Doorn, NL; Wilson, J | 1 |
| Behrens, PF; Franz, P; Landwehrmeyer, GB; Lindenberg, KS; Woodman, B | 1 |
| Dziobek, K; Srebro, Z | 1 |
| Aussel, C; Blonde-Cynober, F; Cynober, L | 1 |
| Ariza, A; Beyer, K; Fernández-Figueras, MT; Lao, JI; Latorre, P; Mate, JL; Matute, B; Riutort, N | 1 |
| HUDSON, PB; REINER, JM | 1 |
| VERNADAKIS, A; WOODBURY, DM | 1 |
| KRZALIC, L; MIHAILOVIC, L | 1 |
| BERL, S | 1 |
| Alles, S; Attaix, D; Brajon, B; Leydier, I; Meynial-Denis, D; Mezzarobba, V; Mignon, M; Torrent, A | 1 |
| Chen, S; Kopelen, HA; Lutucuta, S; Marian, AJ; Nagueh, SF; Patel, R; Quiñones, MA; Roberts, R; Tsybouleva, N; Zoghbi, WA | 1 |
| Cynober, L; Minet-Quinard, R; Moinard, C; Vasson, MP; Villie, F | 1 |
| Detrich, HW; Frankfurter, A; Parker, SK; Redeker, V; Rossier, J | 1 |
| Cashdollar, N; Kaiser, LG; Schuff, N; Weiner, MW | 1 |
| Cooper, JD; Griffin, JL; Mitchison, HM; Mortishire-Smith, RJ; Pearce, DA; Pears, MR | 1 |
| Deutz, NE; Engelen, MP; Rutten, EP; Schols, AM; Wouters, EF | 1 |
| Csermely, P; Soti, C | 1 |
| Desmoulin, F; Dumonteil, N; Galinier, M; Harmancey, R; Hennig, S; Malet-Martino, M; Massabuau, P; Pathak, A; Perez, L; Roncalli, J; Rouet, P; Senard, JM; Smih, F | 1 |
| Humphrey, BD; Rudrappa, SG | 1 |
| Franco, JR; Murakami, AE; Natali, MR; Sakamoto, MI; Souza, LM | 1 |
| Huupponen, J; Lauri, SE; Molchanova, SM; Taira, T | 1 |
| Gu, Z; Lipton, SA; Nakamura, T | 1 |
| Roth, E | 1 |
| Bartell, SM; Batal, AB | 1 |
| Bastholm, IA; Melø, TM; Nehlig, A; Sonnewald, U | 1 |
| Bloemendal, H; Boelens, WC; Boros, S; de Jong, WW; Kamps, B; Lampi, K; Wilmarth, PA | 1 |
| Moscona, AA; Piddington, R | 1 |
| Tyce, GM; Wong, KL | 1 |
| Ito, M; Kikuchi, S; Matsumoto, H | 1 |
| Atkinson, DJ; Balázs, R; Brooksbank, BW | 1 |
| Radha, E; Rajeswari, TS | 1 |
| Christensen, HN; Vadgama, JV | 1 |
| Grüttner, R; Held, KR; Koepp, P; Plettner, C | 1 |
| George, JP; Solomon, S | 2 |
| de Koning-Verest, IF | 1 |
| Csaba, G; Feuer, L; Nagy, SU; Sudár, F | 1 |
| Bazer, FW; Tou, W; Wu, G | 1 |
| Dawson, R; Eppler, B; Patterson, TA | 1 |
| Knabe, DA; Wu, G | 1 |
| Chang, C; Jang, T | 1 |
| Dugan, ME; Knabe, DA; Wu, G | 1 |
| Eisemann, JH; Huntington, GB | 1 |
| Flynn, NE; Knabe, DA; Wu, G; Yan, W | 1 |
| Alvarez Gonzalez, ML; Bourguignon, JP; Franchimont, P; Gerard, A; Purnelle, G | 1 |
| Janáky, R; Marnela, KM; Oja, SS; Saransaari, P; Varga, V | 1 |
| Kilberg, MS; Singh, HP; Tamarappoo, BK | 1 |
| Fleming, SE; Kight, CE | 1 |
| Higuchi, K; Naiki, H; Nakakuki, K; Shimada, A; Takeda, T | 1 |
| Mahapatro, N; Patnaik, BK | 1 |
| Arola, LI; Salvadó, MJ | 1 |
| Fitch, MD; Fleming, SE; Hudes, M | 1 |
| Curi, R; De Almeida, AF; Rosa, LF; Safi, DA | 1 |
| Burzynski, SR | 1 |
| Magnusson, KR | 1 |
| Chang, L; Ernst, T; Jenden, DJ; Poland, RE | 1 |
| Griffiths, RD | 1 |
| Dwarte, D; Evans, G; Maxwell, WM; O'Brien, JK; Ryan, JP | 1 |
| Gomez, J; Grove, J; Kentroti, S; Vernadakis, A | 1 |
| Breitkreutz, R; Drings, P; Dröge, W; Hack, V; Holm, E; Kinscherf, R; Schmid, D; Stahl-Henning, C; Taut, F | 1 |
| Flynn, NE; Wu, G | 1 |
| Abe, M; Funaba, M; Iriki, T | 1 |
| Hasebe, K; Hashimoto, T; Ito, H; Miwa, K; Onishi, I; Sakamoto, K; Shimizu, K; Tani, T; Yagi, M | 1 |
| Field, CJ; McBurney, MI; Yoo, SS | 1 |
| Fitch, MD; Fleming, SE; Zambell, KL | 1 |
| Fletcher, EL; Kalloniatis, M | 1 |
| Boyle, D; Takemoto, L | 2 |
| Carroll, PV; Jackson, NC; Russell-Jones, DL; Sönksen, PH; Treacher, DF; Umpleby, AM | 1 |
| Lindberg, JE; Lundh, T; Madej, M | 1 |
| Chopineau, J; Cynober, L; Minet-Quinard, R; Moinard, C; Vasson, MP; Villie, F; Walrand, S | 1 |
| Darmaun, D; Deschamps, JY; Krempf, M; Marchini, JS; Maugère, P; Nguyen, P | 1 |
| Cullen, MJ; Dawson, R; Gollub, M; Liu, S; Pelleymounter, MA | 1 |
| Bérard, MP; Cézard, JP; Cynober, L; Davot, P; Farges, MC; Joly, B; Raul, F; Vasson, MP | 1 |
| Bruunsgaard, H; Hansen, H; Jensen, M; Ostrowski, K; Pedersen, BK; Toft, AD | 1 |
| Arner, EC; Pratta, MA; Tortorella, MD | 1 |
| Apkarian, AV; Grachev, ID | 1 |
| Apkarian, AV; Grachev, ID; Ramachandran, TS; Swarnkar, A; Szeverenyi, NM | 1 |
| Del Arco, A; Mora, F; Prieto, L; Segovia, G | 1 |
| Takemoto, L | 1 |
| Esquifino, AI; Fenández-Rey, E; Lafuente, A; Pérez-Lorenzo, M; Seara, R | 1 |
| Begue, RJ; Boirie, Y; Meynial-Denis, D; Mignon, M; Van Drieesche, S; Verdier, L | 1 |
| Spindler, SR | 1 |
| Choy, HE; Kim, JH; Nam, KH; Park, SC | 1 |
| Braun, K; Gruss, M | 1 |
| Esquifino, AI; Lafuente, A | 1 |
| Chadha, PL; Crandall, SC; Qureshi, T; Sumida, KD | 1 |
| Fonda, ML; Kirzinger, SS | 1 |
| Kern, HL | 1 |
| Leusen, I; Van Leuven, F; Weyne, J | 2 |
| Franklin, C; Goldstein, L | 1 |
| Huang, YZ; Knox, EW | 1 |
| McKerrow, JH | 1 |
| Hertz, L; Kvamme, E; Schousboe, A; Svenneby, G | 1 |
| Robinson, AB; Robinson, LR; Willoughby, R | 1 |
| Ronda, G; Van den Berg, CJ | 1 |
| Abumrad, N; Dykes, W; Ghishan, FK; Shewayhat, W | 1 |
| Bernardi, G; Calabresi, P; De Murtas, M; Mercuri, NB | 1 |
| Yin, DZ | 1 |
| Ball, WD; Hand, AR; Mirels, L; Moreira, JE | 1 |
| Mora, F | 1 |
| Curi, CM; Curi, R; Fernandes, LC; Ursini, F; Vugman, M | 1 |
| Keast, D; Nguyen, DT | 1 |
| Gross, KL; Hartman, WJ; Meydani, SN; Prior, RL; Ronnenberg, AG | 1 |
| Bennett, LE; Keku, EO; Lecce, JG; Quinn, J; Rhoads, JM | 1 |
| D'Agata, V; Drago, F; Freni, V; Grassi, M; Nardo, L; Raffaele, R; Spadaro, F; Valerio, C | 1 |
| Richter, K; Wolf, G | 1 |
| Abumrad, N; al-Mahroos, FT; Bulus, N; Ghishan, FK; Said, H | 1 |
| Abumrad, N; al-Mahroos, FT; Ghishan, FK | 1 |
| Indira, K; Mohan, PK; Reddy, LV; Satyanarayana, N | 1 |
| Keast, D; Newsholme, EA; Nguyen, T | 1 |
| Mandel, ID; Morgan, B; Naini, A | 1 |
| Banay-Schwartz, M; Lajtha, A; Palkovits, M | 1 |
| Ito, M; Matsumoto, H | 1 |
| Gnaedinger, JM; Miller, JC; Rapoport, SI | 1 |
| Bezold, LI; Kimatian, SJ; McKenna, MC; Tildon, JT | 1 |
| Goldman, JE; Peterson, C | 1 |
| Kador, PF; Kinoshita, JH; Shiono, T | 1 |
| Morris, JG | 1 |
| Greengard, O; Richards, TC | 1 |
| Robinson, AB; Rudd, CJ | 1 |
| Armstrong, MD; Stave, U | 1 |
| Bemiller, JN; Hoffmann, WE; Pappelis, AJ | 1 |
| Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
| Corbin, J; Pennington, W; Roach, MK | 1 |
| De Luca, F; Macaione, S; Ruggeri, P; Tucci, G | 1 |
| Balázs, R; Cremer, JE; Michaelson, IA; Patel, AJ | 1 |
| Agrawal, HC; Davis, JM; Himwich, WA | 1 |
| Aga, AE; Beckmann, R; Clotten, R | 1 |
| Fondy, TP; Ross, CR; Solomon, J | 1 |
| Kuttner, RE; Lorincz, AB | 1 |
| Adler, S; Beard, E; Lindeman, RD; Shock, NW; Yiengst, MJ | 1 |
21 review(s) available for glutamine and Aging
| Article | Year |
|---|---|
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
The far-reaching HAND of cART: cART effects on astrocytes.
Topics: Aging; AIDS Dementia Complex; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Calcium; Cellular Senescence; Central Nervous System; Glucose; Glutamic Acid; Glutamine; HIV Infections; HIV-1; Humans; Mitochondria; Neurocognitive Disorders; Oxidative Stress; Phenotype; Prevalence; Rats | 2021 |
Mitochondrial sirtuins and their relationships with metabolic disease and cancer.
Topics: Aging; Animals; Carcinogenesis; Glutamine; Homeostasis; Humans; Metabolic Diseases; Mitochondrial Proteins; Neoplasms; Sirtuins | 2015 |
The role of mammalian sirtuins in cancer metabolism.
Topics: Aging; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Glutamine; Glycolysis; Humans; Mice; Mitochondria; Neoplasms; Signal Transduction; Sirtuins | 2015 |
Glutamine metabolism in advanced age.
Topics: Aging; Animals; Citrulline; Glutamine; Humans; Intestinal Mucosa; Intestines | 2016 |
13C MRS studies of neuroenergetics and neurotransmitter cycling in humans.
Topics: Aging; Alzheimer Disease; Animals; Brain; Carbon Isotopes; Citric Acid Cycle; Energy Metabolism; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neurons; Neurotransmitter Agents | 2011 |
Neuroprotection: the role of neuroglia.
Topics: Aging; Animals; Apoptosis; Astrocytes; Brain; Energy Metabolism; Free Radicals; Glutamine; Humans; Microglia; Neuroglia; Reactive Oxygen Species | 2001 |
Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients.
Topics: Aged; Aged, 80 and over; Aging; Female; Glutamine; Humans; Male; Nutrition Disorders; Nutritional Status; Ornithine | 2003 |
Pharmacological modulation of the heat shock response.
Topics: Aging; Animals; Aspirin; Cytoprotection; Electromagnetic Fields; Glutamine; Heat-Shock Response; HSP90 Heat-Shock Proteins; Humans; Molecular Chaperones; Myocardial Reperfusion Injury; Zinc | 2006 |
Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases.
Topics: Aged; Aging; Animals; Brain; Calcium; Glutamine; Humans; Neurodegenerative Diseases; Nitric Oxide; Nitrogen; Protein Conformation; Protein Denaturation; Protein Disulfide-Isomerases; Protein Folding; Signal Transduction | 2007 |
Immune and cell modulation by amino acids.
Topics: Aging; Cell Physiological Phenomena; Critical Illness; Glutamine; HSP70 Heat-Shock Proteins; Humans; Immunity, Cellular; Muscular Atrophy; Oxidative Stress | 2007 |
Potential of antineoplastons in diseases of old age.
Topics: Aged; Aging; Animals; Antineoplastic Agents; Benzeneacetamides; Drug Combinations; Glutamine; Growth Inhibitors; Humans; Neoplasms; Peptides; Phenylacetates; Piperidones | 1995 |
Muscle mass, survival, and the elderly ICU patient.
Topics: Aged; Aging; Critical Illness; Glutamine; Humans; Intensive Care Units; Muscle, Skeletal; Survival Rate | 1996 |
Exercise and the immune system--influence of nutrition and ageing.
Topics: Aging; Animals; Exercise; Glutamine; Humans; Immunity; Lymphocytes; Nutritional Physiological Phenomena | 1999 |
Calorie restriction enhances the expression of key metabolic enzymes associated with protein renewal during aging.
Topics: Aging; Amino Acids; Animals; Carbon; Energy Intake; Energy Metabolism; Enzyme Induction; Food Deprivation; Gluconeogenesis; Glutaminase; Glutamine; Glycogen; Glycolysis; Hepatocytes; Liver; Mice; Models, Biological; Muscle Proteins; Muscle, Skeletal; Nitrogen; Phosphoenolpyruvate Carboxykinase (GTP); Proteins; RNA, Messenger | 2001 |
Transglutaminase-mediated crosslinking of specific core histone subunits and cellular senescence.
Topics: Aging; Animals; Brain; Cell Nucleus; Cells, Cultured; Cellular Senescence; Cross-Linking Reagents; Cytoplasm; Fibroblasts; Glutamine; Histones; Humans; Isoenzymes; Liver; Lysine; Macromolecular Substances; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Phenotype; Protein Subunits; Rats; Rats, Sprague-Dawley; Transglutaminases | 2001 |
Transport of organic solutes in the lens.
Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Calcium; Carbohydrate Metabolism; Cataract; Cattle; Chick Embryo; Cycloleucine; gamma-Glutamyltransferase; Glutamine; Lens, Crystalline; Peptides; Polymers; Rats; Serine; Sodium | 1979 |
Non-enzymatic, post-translational, amino acid modifications in ageing. A brief review.
Topics: Aging; Amides; Amino Acids; Animals; Asparagine; Aspartic Acid; Glutamine; Half-Life; Isomerism; Models, Biological; Oligopeptides; Proteins; Rats; Structure-Activity Relationship | 1979 |
Energy metabolism and the skin.
Topics: Aging; Animals; Energy Metabolism; Glucose; Glutamine; Glycogen; Skin; Stress, Physiological; Wound Healing | 1991 |
Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.
Topics: Aging; Amides; Amino Acid Sequence; Animals; Ascorbic Acid; Asparagine; Bacterial Proteins; Biological Evolution; Cytochrome c Group; Escherichia coli; Fructose-Bisphosphate Aldolase; Glutamine; Histones; Humans; Hydrogen-Ion Concentration; Hydrolysis; Muramidase; Oxygen; Peptides; Proteins; Temperature | 1974 |
Maturational changes in amino acids in CNS of different mammalian species.
Topics: Aging; Amino Acids; Amino Alcohols; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Cats; Dogs; Glutamates; Glutamine; Guinea Pigs; Phosphates; Rabbits; Rats; Taurine | 1968 |
6 trial(s) available for glutamine and Aging
| Article | Year |
|---|---|
Effects of 6-month supplementation with β-hydroxy-β-methylbutyrate, glutamine and arginine on vascular endothelial function of older adults.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Brachial Artery; C-Reactive Protein; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Fasting; Female; Glutamine; Humans; Male; Tumor Necrosis Factor-alpha; Valerates; Vasodilation | 2016 |
The safety of oral use of L-glutamine in middle-aged and elderly individuals.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Biomarkers; Blood Urea Nitrogen; Caseins; Creatinine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Glomerular Filtration Rate; Glutamine; Humans; Kidney; Liver; Male; Middle Aged | 2010 |
Supplementation of glutamine and vitamin E on the morphometry of the intestinal mucosa in broiler chickens.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Duodenum; Glutamine; Ileum; Intestinal Mucosa; Jejunum; Male; Vitamin E | 2007 |
The effect of supplemental glutamine on growth performance, development of the gastrointestinal tract, and humoral immune response of broilers.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antibody Formation; Bile; Chickens; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Drug Administration Schedule; Gastrointestinal Tract; Glutamine; Immunoglobulins; Intestines; Male; Weight Gain | 2007 |
Aging alters regional multichemical profile of the human brain: an in vivo 1H-MRS study of young versus middle-aged subjects.
Topics: Adult; Age Factors; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values | 2001 |
Aging alters the multichemical networking profile of the human brain: an in vivo (1)H-MRS study of young versus middle-aged subjects.
Topics: Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Net; Organ Specificity | 2001 |
162 other study(ies) available for glutamine and Aging
| Article | Year |
|---|---|
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice.
Topics: Adenosine Triphosphate; Aging; Animals; Color Vision; Electroretinography; Flicker Fusion; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Light; Male; Metabolomics; Mice; Mice, Inbred C57BL; Night Vision; Oxygen Consumption; Photic Stimulation; Retina; Retinal Pigment Epithelium | 2021 |
Changes in aging-induced kidney dysfunction in mice based on a metabolomics analysis.
Topics: Aging; Animals; Biomarkers; Citrates; Glutamic Acid; Glutamine; Glyoxylates; Histidine; Kidney; Male; Mice; Nucleotides; Purines; Pyruvates; Renal Insufficiency; Tricarboxylic Acids | 2022 |
Serum Metabolomic Profiling in Aging Mice Using Liquid Chromatography-Mass Spectrometry.
Topics: Aging; Animals; Biomarkers; Chromatography, Liquid; Glutamine; Mass Spectrometry; Mice; Oleic Acids | 2022 |
Neurometabolic correlates of posturography in normal aging and older adults with mild cognitive impairment: Evidence from a
Topics: Aged; Aging; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Glutamine; Humans; Inositol; Proton Magnetic Resonance Spectroscopy; Receptors, Antigen, T-Cell | 2023 |
Study on the targeted regulation of Scutellaria baicalensis leaf on glutamine-glutamate metabolism and glutathione synthesis in the liver of d-gal ageing rats.
Topics: Aging; Animals; Glutamic Acid; Glutamine; Glutathione; Liver; NF-E2-Related Factor 2; Plant Leaves; Rats; Scutellaria baicalensis | 2023 |
Decreased autophagy and fuel switching occur in a senescent hepatic cell model system.
Topics: Aging; Animals; Autophagy; Cell Line; Cellular Senescence; Energy Metabolism; Gene Expression Regulation; Glutamine; Glycolysis; Hepatitis; Hepatocytes; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Phenotype; TOR Serine-Threonine Kinases | 2020 |
Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
Topics: Aging; Amino Acid Transport System ASC; Animals; Cell Differentiation; Cell Proliferation; Female; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Macrophages; Male; Mice; Minor Histocompatibility Antigens; Muscle, Skeletal; Oxidation-Reduction; Regeneration; Satellite Cells, Skeletal Muscle; TOR Serine-Threonine Kinases | 2020 |
Glutamine, fatty liver disease and aging.
Topics: Aging; Animals; Glutamine; Humans; Liver; Mice; Non-alcoholic Fatty Liver Disease | 2021 |
Glutamine Linked to Cell Senescence and Aging.
Topics: Aging; Cellular Senescence; Glutamine; Humans | 2021 |
3T hippocampal glutamate-glutamine complex reflects verbal memory decline in aging.
Topics: Adult; Aged; Aging; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Memory Disorders; Verbal Behavior | 2017 |
Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction.
Topics: Adipocytes; Aging; Animals; Animals, Newborn; Cell Death; Cell Differentiation; Chondrocytes; Chromatin; Gene Expression Regulation; Glutamine; Histones; Hypoxia-Inducible Factor 1, alpha Subunit; Ketoglutaric Acids; Mesenchymal Stem Cells; Metabolome; Mice; Mice, Knockout; Mitochondria; Osteoblasts; Primary Cell Culture; Pyruvic Acid; Reactive Oxygen Species; Skin; Superoxide Dismutase | 2017 |
Arginine CGA codons as a source of nonsense mutations: a possible role in multivariant gene expression, control of mRNA quality, and aging.
Topics: Aging; Alternative Splicing; Arginine; Catalase; Codon, Nonsense; DNA Methylation; Gene Expression; Glutamine; Humans; Nonsense Mediated mRNA Decay; RNA, Messenger; Selenocysteine; Selenoproteins | 2017 |
Glutamate homeostasis in the adult rat prefrontal cortex is altered by cortical docosahexaenoic acid accrual during adolescence: An in vivo
Topics: Aging; Amino Acid Transport System X-AG; Animals; Astrocytes; Diet; Docosahexaenoic Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Homeostasis; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Long-Evans | 2017 |
Aging-associated changes in hippocampal glycogen metabolism in mice. Evidence for and against astrocyte-to-neuron lactate shuttle.
Topics: Aging; Animals; Astrocytes; Glutamine; Glycogen; Hippocampus; Male; Mice, Inbred C57BL; Mitochondria; Neurons; Proteome | 2018 |
The age-related changes and differences in energy metabolism and glutamate-glutamine recycling in the d-gal-induced and naturally occurring senescent astrocytes in vitro.
Topics: Aging; Animals; Astrocytes; Cells, Cultured; Cellular Senescence; Energy Metabolism; Galactose; Glutamic Acid; Glutamine; Glycolysis; Mitochondria; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2019 |
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome | 2019 |
Longer Repetition Time Proton MR Spectroscopy Shows Increasing Hippocampal and Parahippocampal Metabolite Concentrations with Aging.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Male; Middle Aged; Parahippocampal Gyrus; Proton Magnetic Resonance Spectroscopy; Protons; Young Adult | 2019 |
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Glutamic Acid; Glutamine; Glutathione; Glycerylphosphorylcholine; Humans; Inositol; Insulin Resistance; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Neuronal Plasticity; Phosphocreatine; Phosphorylcholine; Prediabetic State; Theta Rhythm; Transcranial Magnetic Stimulation | 2019 |
Effects of age and sex on the concentrations of glutamate and glutamine in the human brain.
Topics: Adult; Aging; Aspartic Acid; Choline; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Reproducibility of Results; Sensitivity and Specificity; Sex Factors; Young Adult | 2013 |
Consequences of age-related splanchnic sequestration of leucine on interorgan glutamine metabolism in old rats.
Topics: Aging; Amino Acids; Animals; Body Weight; Eating; Glutamine; Homeostasis; Intestinal Mucosa; Intestines; Kidney; Leucine; Liver; Male; Muscles; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Veins | 2013 |
Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations.
Topics: Aged; Aging; Cresols; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Sex Characteristics; Sulfuric Acid Esters; Taiwan; United States | 2013 |
Effect of intermittent glutamine supplementation on skeletal muscle is not long-lasting in very old rats.
Topics: Aging; Animals; Dietary Supplements; Female; Glutamate-Ammonia Ligase; Glutamine; Muscle, Skeletal; Rats; Rats, Wistar | 2013 |
Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia.
Topics: Adipose Tissue; Aged; Aging; Body Composition; Body Mass Index; Cachexia; Chronic Disease; Energy Metabolism; Female; Glutamine; Humans; Male; Malnutrition; Muscle Contraction; Muscle, Skeletal; Nutritional Status; Obesity; Prevalence; Sarcopenia | 2014 |
Caloric restriction impedes age-related decline of mitochondrial function and neuronal activity.
Topics: Aging; Animals; Caloric Restriction; Glutamic Acid; Glutamine; Male; Mitochondria; Rats; Rats, Inbred F344; Synaptic Transmission | 2014 |
Age related changes in metabolite concentrations in the normal spinal cord.
Topics: Adult; Age Factors; Aged; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Healthy Volunteers; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Spinal Cord; Young Adult | 2014 |
Long-term intermittent glutamine supplementation repairs intestinal damage (structure and functional mass) with advanced age: assessment with plasma citrulline in a rodent model.
Topics: Aging; Amino Acids; Animals; Body Weight; Citrulline; Dietary Supplements; Drug Administration Schedule; Female; Glutamine; Glutathione; Intestinal Mucosa; Intestine, Small; Liver; Rats; Rats, Wistar; Time Factors | 2014 |
Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents.
Topics: Adolescent; Aging; Alcoholism; Brain Chemistry; Child; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Young Adult | 2015 |
A quantitative analysis of (1)H-MR spectroscopy at 3.0 T of three brain regions from childhood to middle age.
Topics: Adolescent; Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Child; Creatinine; Female; Glutamic Acid; Glutamine; Healthy Volunteers; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matrix Metalloproteinase 9; Middle Aged; Young Adult | 2015 |
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2016 |
Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study.
Topics: Aged; Aging; Chromatography, High Pressure Liquid; Cognition; Depressive Disorder, Major; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Male; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2016 |
Age and High-Fat Diet Effects on Glutamine Synthetase Immunoreactivity in Liver and Hippocampus and Recognition Memory in Mice.
Topics: Aging; Ammonia; Animals; Diet, High-Fat; Fatty Liver; Glutamate-Ammonia Ligase; Glutamine; Hippocampus; Immunohistochemistry; Liver; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity | 2016 |
Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells.
Topics: Aging; Animals; Bone Resorption; Calcification, Physiologic; Cell Differentiation; Cellular Senescence; ERRalpha Estrogen-Related Receptor; Gene Expression Regulation; Glutaminase; Glutamine; Humans; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Mitochondria; Osteogenesis; Promoter Regions, Genetic; Protein Binding; Receptors, Estrogen; RNA, Messenger | 2017 |
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
Topics: Adult; Aged; Aging; Arginine; Aspartic Acid; Cerebellum; Glutamine; Humans; Isoaspartic Acid; Mass Spectrometry; Middle Aged; Models, Molecular; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Protein Processing, Post-Translational; Proteolysis | 2016 |
Altered Glutamate and Regional Cerebral Blood Flow Levels in Schizophrenia: A
Topics: Adolescent; Adult; Aging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenic Psychology; White Matter; Young Adult | 2017 |
Microglia derived from the axotomized adult rat facial nucleus uptake glutamate and metabolize it to glutamine in vitro.
Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Facial Nucleus; Glutamic Acid; Glutamine; Male; Microglia; Neurons; Rats, Wistar | 2017 |
Glutamate-glutamine and GABA in brain of normal aged and patients with cognitive impairment.
Topics: Adult; Aged; Aging; Alzheimer Disease; Analysis of Variance; Case-Control Studies; Cognitive Dysfunction; Early Diagnosis; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult | 2017 |
N-γ-(L-Glutamyl)-L-selenomethionine enhances stress resistance and ameliorates aging indicators via the selenoprotein TRXR-1 in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Glutamine; Larva; Lipofuscin; Mutation; Reactive Oxygen Species; Selenomethionine; Selenoproteins; Stress, Physiological | 2017 |
Refeeding concomitant with glutamine supplementation only decreases muscle glutamine synthesis without body weight recovery in very old fasted male rats.
Topics: Aging; Animals; Body Weight; Dietary Supplements; Fasting; Female; Glutamate-Ammonia Ligase; Glutamine; Male; Muscle, Skeletal; Nutritional Requirements; Rats; Rats, Wistar; Up-Regulation | 2008 |
Mutation screening of HSF4 in 150 age-related cataract patients.
Topics: Aging; Amino Acid Sequence; Base Sequence; Cataract; DNA Mutational Analysis; DNA-Binding Proteins; Genetic Testing; Glutamine; Heat Shock Transcription Factors; Humans; Molecular Sequence Data; Mutation; Transcription Factors | 2008 |
Brain metabolism in Rett syndrome: age, clinical, and genotype correlations.
Topics: Adolescent; Aging; Analysis of Variance; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Female; Frontal Lobe; Genotype; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Methyl-CpG-Binding Protein 2; Mutation; Protons; Rett Syndrome; Severity of Illness Index | 2009 |
Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats.
Topics: Acetates; Aging; Amino Acids; Animals; Carbon Dioxide; Central Nervous System Agents; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glutamine; Glycine; Glyoxal; Lactic Acid; Lipid Metabolism; Male; Oxidation-Reduction; Protein Biosynthesis; Pyruvaldehyde; Rats; Rats, Wistar | 2010 |
Age-dependent deamidation of lifelong proteins in the human lens.
Topics: Aged; Aged, 80 and over; Aging; Asparagine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Gestational Age; Glutamine; Humans; Lens, Crystalline; Middle Aged; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Metabolite concentrations in supraventricular white matter from teenage to early old age: A short echo time 1H magnetic resonance spectroscopy (MRS) study.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myelin Sheath; Reference Values; Young Adult | 2010 |
Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.
Topics: Aging; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; DNA, Complementary; Glutamine; GTP Phosphohydrolases; Humans; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Electron; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mutation; Nerve Fibers, Myelinated; Neurons; Peripheral Nerves; Phenotype; Sciatic Nerve | 2010 |
Accelerated removal of deamidated proteins and endogenous electric fields: possible implications.
Topics: Aging; Asparagine; Biophysical Phenomena; Electricity; Glutamine; Isoelectric Point; Models, Biological; Peptide Hydrolases; Protein Folding; Proteins | 2010 |
Tryptophan boost caused by senescence occurred independently of cytoplasmic glutamine synthetase.
Topics: Aging; Cytosol; Glutamate-Ammonia Ligase; Glutamine; Oryza; Plants, Genetically Modified; RNA Interference; RNA, Messenger; Tryptophan | 2010 |
Age-dependent deamidation of glutamine residues in human γS crystallin: deamidation and unstructured regions.
Topics: Adolescent; Adult; Aged, 80 and over; Aging; Amides; Amino Acid Sequence; Cataract; Child; gamma-Crystallins; Glutamine; Humans; Infant, Newborn; Lens, Crystalline; Middle Aged; Models, Molecular; Protein Structure, Secondary; Young Adult | 2012 |
Glutamate and CO2 production from glutamine in incubated enterocytes of adult and very old rats.
Topics: Aging; Animals; Carbon Dioxide; Enterocytes; Glutamic Acid; Glutamine; Rats; Rats, Wistar | 2013 |
Site-specific deamidation of glutamine: a new marker of bone collagen deterioration.
Topics: Aging; Amides; Animals; Archaeology; Biomarkers; Collagen Type I; Europe; Glutamine; Humans; Mass Spectrometry; Spectroscopy, Fourier Transform Infrared; Temperature | 2012 |
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation.
Topics: Aging; Animals; Biological Transport; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microdialysis; Mutation; Nerve Tissue Proteins; Nuclear Proteins | 2002 |
Methionine synthase polymorphism is a risk factor for Alzheimer disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Age of Onset; Aged; Aged, 80 and over; Aging; Alanine; Alzheimer Disease; Apolipoproteins E; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Logistic Models; Male; Middle Aged; Mutation; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Sex Characteristics | 2003 |
Effect of age upon glutamine synthesis and glutamine amide exchange of rat liver, kidney and testis.
Topics: Aging; Amides; Animals; Glutamine; Humans; Kidney; Liver; Male; Rats; Testis | 1953 |
Electrolyte and amino acid changes in rat brain during maturation.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Brain; Chlorides; Glutamates; Glutamine; Nitrogen; Potassium; Rats; Sodium; Threonine | 1962 |
CHANGES IN GLUTAMIC ACID, GLUTAMINE, AND GAMMA-AMINOBUTYRIC ACID CONCENTRATIONS DURING POSTNATAL MATURATION OF THE CAT BRAIN.
Topics: Aging; Aminobutyrates; Brain; Brain Chemistry; Cats; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Research | 1964 |
COMPARTMENTATION OF GLUTAMIC ACID METABOLISM IN DEVELOPING CEREBRAL CORTEX.
Topics: Aging; Amino Acids; Aminobutyrates; Animals; Animals, Newborn; Aspartic Acid; Brain Chemistry; Cats; Cerebral Cortex; Glutamates; Glutamine; Glutathione; Growth; Research | 1965 |
The role of adrenal hormones in the response of glutamine synthetase to fasting in adult and old rats.
Topics: Adrenal Glands; Adrenalectomy; Age Factors; Aging; Analysis of Variance; Animals; Blotting, Northern; Fasting; Glucocorticoids; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hormone Antagonists; Male; Mifepristone; Muscle, Skeletal; Rats; Rats, Wistar; RNA, Messenger | 2003 |
Evolution of expression of cardiac phenotypes over a 4-year period in the beta-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy.
Topics: Adenosine Triphosphatases; Aging; Animals; Animals, Genetically Modified; Calcium; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Echocardiography; Glutamine; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myofibrils; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Phenotype; Rabbits; Signal Transduction; Time Factors; Transgenes | 2004 |
Metabolic pathways implicated in the kinetic impairment of muscle glutamine homeostasis in adult and old glucocorticoid-treated rats.
Topics: Aging; Animals; Body Weight; Dexamethasone; Eating; Glucocorticoids; Glutamate-Ammonia Ligase; Glutamine; Homeostasis; Kinetics; Male; Muscle Proteins; Muscle, Skeletal; Organ Size; Rats; Rats, Sprague-Dawley | 2004 |
Posttranslational modification of brain tubulins from the Antarctic fish Notothenia coriiceps: reduced C-terminal glutamylation correlates with efficient microtubule assembly at low temperature.
Topics: Aging; Amino Acid Sequence; Animals; Animals, Newborn; Antarctic Regions; Brain; Chromatography, High Pressure Liquid; Cold Temperature; DNA, Complementary; Glutamine; Microtubules; Molecular Sequence Data; Perciformes; Protein Isoforms; Protein Processing, Post-Translational; Proteomics; Rats; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin | 2004 |
Age-related glutamate and glutamine concentration changes in normal human brain: 1H MR spectroscopy study at 4 T.
Topics: Adult; Aged; Aging; Analysis of Variance; Aspartic Acid; Brain Chemistry; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Protons; Statistics as Topic | 2005 |
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.
Topics: Aging; Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Knockout; Models, Biological; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neurotransmitter Agents; Phenotype; Spectrophotometry; Time Factors | 2005 |
Effect of glutamate ingestion on whole-body glutamate turnover in healthy elderly and patients with chronic obstructive pulmonary disease.
Topics: Aged; Aging; Case-Control Studies; Dietary Supplements; Glutamic Acid; Glutamine; Health Status; Humans; Male; Middle Aged; Nitrogen Isotopes; Postprandial Period; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests | 2006 |
NMR and cDNA array analysis prior to heart failure reveals an increase of unsaturated lipids, a glutamine/glutamate ratio decrease and a specific transcriptome adaptation in obese rat heart.
Topics: Adaptation, Biological; Aging; Animals; Gene Expression Profiling; Glutamates; Glutamine; Heart Failure; Intracellular Membranes; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Multigene Family; Obesity; Oligonucleotide Array Sequence Analysis; Phenotype; Rats; Transcription, Genetic | 2007 |
Energy metabolism in developing chicken lymphocytes is altered during the embryonic to posthatch transition.
Topics: Aging; Animals; Bursa of Fabricius; Chick Embryo; Chickens; Energy Metabolism; Gene Expression Regulation, Developmental; Glucose; Glutamine; Lipid Metabolism; Lymphocytes; RNA, Messenger; Thymus Gland | 2007 |
Susceptibility for homeostatic plasticity is down-regulated in parallel with maturation of the rat hippocampal synaptic circuitry.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Down-Regulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamine; Hippocampus; Homeostasis; Inhibitory Postsynaptic Potentials; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin; Time Factors | 2007 |
Astrocytes may play a role in the etiology of absence epilepsy: a comparison between immature GAERS not yet expressing seizures and adults.
Topics: Acetic Acid; Aging; Animals; Astrocytes; Brain; Cell Communication; Cell Differentiation; Disease Models, Animal; Energy Metabolism; Epilepsy; Epilepsy, Absence; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamine; Magnetic Resonance Spectroscopy; Male; Mitochondria; Neural Inhibition; Neurons; Rats; Up-Regulation | 2007 |
Tissue transglutaminase catalyzes the deamidation of glutamines in lens betaB(2)- and betaB(3)-crystallins.
Topics: Aging; Amides; Animals; beta-Crystallin B Chain; Catalysis; Cattle; Fetus; Glutamine; GTP-Binding Proteins; Humans; In Vitro Techniques; Lens, Crystalline; Middle Aged; Protein Glutamine gamma Glutamyltransferase 2; Proteome; Transglutaminases | 2008 |
Precocious induction of retinal glutamine synthetase by hydrocortisone in the embryo and in culture. Age-dependent differences in tissue response.
Topics: Aging; Animals; Chick Embryo; Culture Techniques; Enzyme Induction; Glutamine; Hydrocortisone; Ligases; Retina | 1967 |
Conversion of glucose to neurotransmitter amino acids in the brains of young and aging rats.
Topics: Age Factors; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Neurotransmitter Agents; Pyridoxal Phosphate; Rats | 1980 |
Age-related changes in the glutamate metabolism of cerebral cortical slices from rats.
Topics: Aging; Animals; Aspartic Acid; Carbon Dioxide; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1982 |
Biochemical development of the human brain. III. Benzodiazepine receptors, free gamma-aminobutyrate (GABA) and other amino acids.
Topics: Adult; Aged; Aging; Amino Acids; Aspartic Acid; Brain; Cerebellum; Female; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Gestational Age; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Kinetics; Middle Aged; Pregnancy; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Metabolism of the glutamate group of amino acids in rat brain as a function of age.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Energy Metabolism; Enzymes; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Male; Rats; Rats, Inbred Strains | 1984 |
Comparison of system N in fetal hepatocytes and in related cell lines.
Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Line; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Lithium; Liver; Liver Neoplasms; Sodium | 1983 |
Plasma amino acid pattern at noon in early treated hyperphenylalaninemic, phenylketonuric, and normal children.
Topics: Adolescent; Aging; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Female; Glutamine; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Time Factors | 1983 |
Effect of acute and chronic acidosis on glutamine uptake in kidney slices of newborn rats.
Topics: Acidosis; Acute Disease; Aging; Ammonium Chloride; Animals; Animals, Newborn; Biological Transport; Chronic Disease; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Rats | 1982 |
Glutamate metabolism in ageing rat brain.
Topics: Acetates; Aging; Animals; Aspartic Acid; Brain; Female; Glucose; Glutamates; Glutamine; Rats | 1980 |
The effect of glutaurine (gamma-L-glutamyl-taurine) on the division of rat thymus cells.
Topics: Aging; Animals; Animals, Newborn; Cattle; Cell Division; Glutamine; Male; Rats; Taurine; Thymus Gland | 1980 |
Developmental changes of free amino acid concentrations in fetal fluids of pigs.
Topics: Aging; Allantois; Amino Acids; Ammonia; Amniotic Fluid; Animals; Arginine; Female; Fetal Blood; Gestational Age; Glutamine; Glycine; Male; Ornithine; Placenta; Pregnancy; Swine; Urea; Uterus | 1995 |
Endogenous excitatory amino acid release from brain slices and astrocyte cultures evoked by trimethyltin and other neurotoxic agents.
Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Neurotoxins; Ouabain; Potassium Chloride; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sodium Glutamate; Taurine; Trimethyltin Compounds; Veratrine | 1995 |
Arginine synthesis in enterocytes of neonatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Body Fluids; Citrulline; DNA; Glutamine; Jejunum; Kidney; Ornithine; Osmolar Concentration; Proline; Swine | 1995 |
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies.
Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Rats; Rats, Sprague-Dawley | 1995 |
The induction of citrulline synthesis from glutamine in enterocytes of weaned pigs is not due primarily to age or change in diet.
Topics: Aging; Animals; Animals, Suckling; Cells, Cultured; Citrulline; Diet; Food Deprivation; Glutamine; Glycine max; Jejunum; Swine; Time Factors; Weaning; Zea mays | 1995 |
Metabolite flux across portal-drained viscera, liver, and hindquarters of hyperinsulinemic, euglycemic beef steers.
Topics: Aging; Alanine; Animals; Biological Transport; Body Weight; Cattle; Glucose; Glucose Clamp Technique; Glutamic Acid; Glutamine; Hyperinsulinism; Insulin; Liver; Male; Muscle, Skeletal; Portal Vein; Random Allocation; Viscera | 1994 |
Glutamine and glucose metabolism in enterocytes of the neonatal pig.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Arginine; Citrulline; Glucose; Glutamine; Jejunum; Oxygen Consumption; Swine | 1995 |
Endogenous glutamate involvement in pulsatile secretion of gonadotropin-releasing hormone: evidence from effect of glutamine and developmental changes.
Topics: Aging; Animals; Diazooxonorleucine; Glutamates; Glutamic Acid; Glutamine; Gonadotropin-Releasing Hormone; Male; Pulsatile Flow; Rats; Rats, Wistar; Veratridine | 1995 |
Interactions of gamma-L-glutamyltaurine with excitatory aminoacidergic neurotransmission.
Topics: Aging; Animals; Aspartic Acid; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclic GMP; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kainic Acid; Mice; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Stereoisomerism; Synaptic Transmission; Synaptosomes; Taurine | 1994 |
Protein modification of glutamine transporters in SV40-transformed hepatocytes and immunodetection of proteins associated with hepatic system N transport activity.
Topics: Aging; Amino Acid Transport Systems, Basic; Animals; Antibodies, Monoclonal; Biological Transport, Active; Carrier Proteins; Cell Line, Transformed; Electrophoresis, Polyacrylamide Gel; Fetus; Glutamine; Hybridomas; Liver; Precipitin Tests; Rats; Simian virus 40 | 1994 |
The TCA cycle as an oxidative and synthetic pathway is suppressed with aging in jejunal epithelial cells.
Topics: Aging; Animals; Cells, Cultured; Citrates; Citric Acid; Citric Acid Cycle; Fasting; Glucose; Glutamine; Jejunum; Kinetics; Male; Oxaloacetates; Oxidation-Reduction; Rats; Rats, Inbred F344 | 1994 |
Genetic analysis of murine senile amyloidosis.
Topics: Aging; Amyloidosis; Animals; Dementia; DNA; Genotype; Glutamine; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Protein Precursors; Serum Amyloid A Protein; Spectrometry, Fluorescence | 1993 |
Age-dependent changes in some aspects of glutamate metabolism in the brain of the teleost, Channa punctatus. I. Ammonia and glutamine contents and glutamate dehydrogenase activity.
Topics: Aging; Ammonia; Animals; Brain; Fishes; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutamine; Male | 1993 |
Glutamine force-feeding effect on plasma amino-acid concentrations in growing rats fed a cafeteria diet.
Topics: Aging; Amino Acids; Animals; Cysteine; Diet; Glutamine; Ornithine; Proline; Rats; Rats, Wistar; Threonine; Tyrosine | 1994 |
Intestinal cell respiration is influenced by animal age, strain, and feeding status.
Topics: 3-Hydroxybutyric Acid; Acetates; Aging; Animals; Butyrates; Cells, Cultured; Colon; Fasting; Food; Glucose; Glutamine; Hydroxybutyrates; Jejunum; Male; Oxidation-Reduction; Rats | 1994 |
Metabolic and functional changes in lymphocytes and macrophages as induced by ageing.
Topics: Aging; Animals; Carcinoma 256, Walker; Citrate (si)-Synthase; Citric Acid Cycle; Energy Metabolism; Glucosephosphate Dehydrogenase; Glutaminase; Glutamine; Glycolysis; Hexokinase; Hydrogen Peroxide; Lymphocyte Activation; Lymphocytes; Macrophages; Male; Neoplasm Transplantation; Pentose Phosphate Pathway; Phagocytosis; Rats | 1993 |
Glycine enhances binding to the NMDA receptor complex in aged mice, but does not correct the aging change.
Topics: Aging; Animals; Glutamine; Glycine; In Vitro Techniques; Mice; Mice, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1996 |
In vivo proton magnetic resonance spectroscopy of the normal aging human brain.
Topics: Adult; Aged; Aging; Body Water; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Middle Aged; Protons | 1996 |
Developmental capacity, energy metabolism and ultrastructure of mature oocytes from prepubertal and adult sheep.
Topics: Aging; Animals; Blastocyst; Cytoplasm; Cytoplasmic Granules; Energy Metabolism; Female; Glucose; Glutamine; Mitochondria; Oocytes; Organelles; Pyruvic Acid; Sexual Maturation; Sheep | 1996 |
Plasticity of astrocytes derived from aged mouse cerebral hemispheres: changes with cell passage and immortalization.
Topics: Aging; Animals; Astrocytes; Blotting, Western; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Glutamine; Mice; Mice, Inbred Strains; Nerve Growth Factors; Neuroglia; Neuronal Plasticity | 1996 |
Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence.
Topics: Adipose Tissue; Adolescent; Adult; Aging; Animals; Cachexia; CD4 Lymphocyte Count; Citrulline; Cystine; Female; Glutamine; HIV Infections; Humans; Macaca; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Neoplasms; Simian Acquired Immunodeficiency Syndrome; Taurine | 1997 |
Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs.
Topics: Aging; Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Cells, Cultured; DNA; Enzyme Induction; Female; Glucocorticoids; Glutamine; Hydrocortisone; Jejunum; Male; Mifepristone; Ornithine; Proline; Receptors, Glucocorticoid; Swine; Urea; Weaning | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
Effect of a glutamine-enriched diet on small bowel allograft during immunosuppressive therapy.
Topics: Aging; Alanine; Alkaline Phosphatase; Ammonia; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Diet; Epithelial Cells; Glutamic Acid; Glutamine; Immunosuppression Therapy; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Random Allocation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tacrolimus; Time Factors; Transplantation, Homologous | 1997 |
Glutamine supplementation maintains intramuscular glutamine concentrations and normalizes lymphocyte function in infected early weaned pigs.
Topics: Aging; Amino Acids; Animals; Body Temperature; Carcinogens; Cell Division; Concanavalin A; Diet; Dietary Supplements; DNA; Escherichia coli; Escherichia coli Infections; Glutamine; Immune System; Injections, Intraperitoneal; Ionomycin; Ionophores; Leukocyte Count; Lymphocytes; Muscle, Skeletal; Swine; Swine Diseases; Tetradecanoylphorbol Acetate; Thymidine; Weaning | 1997 |
Glucose and glutamine provide similar proportions of energy to mucosal cells of rat small intestine.
Topics: Aging; Animals; Carbon Radioisotopes; Energy Metabolism; Glucose; Glutamine; Glycolysis; Intestinal Mucosa; Intestine, Small; Male; Radioisotope Dilution Technique; Rats; Rats, Inbred F344; Reproducibility of Results; Tritium | 1997 |
Neurochemical development of the degenerating rat retina.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamine; Glycine; Immunohistochemistry; Neurotransmitter Agents; Rats; Rats, Inbred BUF; Rats, Mutant Strains; Retina; Retinal Degeneration; Taurine | 1997 |
Determination of the in vivo deamidation rate of asparagine-101 from alpha-A crystallin using microdissected sections of the aging human lens.
Topics: Adolescent; Adult; Aging; Amides; Asparagine; Child; Child, Preschool; Crystallins; Dissection; Glutamine; Half-Life; Humans; Lens, Crystalline | 1998 |
Deamidation of specific glutamine residues from alpha-A crystallin during aging of the human lens.
Topics: Adult; Aging; Amides; Child; Crystallins; Glutamine; Half-Life; Humans; Infant; Lens, Crystalline; Middle Aged; Oxidation-Reduction; Peptides; Trypsin | 1998 |
The metabolic consequences of critical illness: acute effects on glutamine and protein metabolism.
Topics: Adult; Aged; Aged, 80 and over; Aging; Critical Care; Critical Illness; Female; Glutamine; Humans; Kinetics; Leucine; Male; Metabolic Clearance Rate; Middle Aged; Osmolar Concentration; Protein Biosynthesis; Proteins; Reference Values; Time Factors | 1999 |
Activities of enzymes involved in glutamine metabolism in connection with energy production in the gastrointestinal tract epithelium of newborn, suckling and weaned piglets.
Topics: Aging; Animals; Animals, Newborn; Animals, Suckling; Digestive System; Energy Metabolism; Epithelium; Glutamine; Swine; Weaning | 1999 |
Kinetic impairment of nitrogen and muscle glutamine metabolisms in old glucocorticoid-treated rats.
Topics: Aging; Animals; Dexamethasone; Glucocorticoids; Glutamine; Kinetics; Male; Muscle, Skeletal; Nitrogen; Organ Size; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors | 1999 |
Effect of intravenous glutamine on duodenal mucosa protein synthesis in healthy growing dogs.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Carbon Isotopes; Dogs; Duodenum; Glutamine; Glycine; Infusions, Intravenous; Intestinal Mucosa; Kinetics; Leucine; Protein Biosynthesis | 1999 |
An age-related decline in striatal taurine is correlated with a loss of dopaminergic markers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biomarkers; Brain-Derived Neurotrophic Factor; Corpus Striatum; Dopamine; Glutamic Acid; Glutamine; Hippocampus; Male; Maze Learning; Nerve Growth Factors; Rats; Rats, Long-Evans; Reaction Time; Space Perception; Taurine; Temporal Lobe | 1999 |
Oral administration of a glutamine-enriched diet before or after endotoxin challenge in aged rats has limited effects.
Topics: Aging; Amino Acids; Animals; Bacterial Translocation; Body Weight; Diet; Endotoxemia; Glutamine; Intestinal Mucosa; Lipopolysaccharides; Male; Muscle, Skeletal; Organ Size; Rats; Rats, Sprague-Dawley | 1999 |
Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase.
Topics: Age Factors; Aggrecans; Aging; Alanine; Animals; beta-Galactosidase; Blotting, Western; Cattle; Chondroitin Sulfates; Chondroitinases and Chondroitin Lyases; Endopeptidases; Extracellular Matrix Proteins; Freezing; Glutamine; Glycosaminoglycans; Glycoside Hydrolases; Glycosylation; Keratan Sulfate; Lectins, C-Type; Matrix Metalloproteinase 3; Phenylalanine; Proteoglycans; Serine; Time Factors | 2000 |
Glutamate-glutamine cycle and aging in striatum of the awake rat: effects of a glutamate transporter blocker.
Topics: Aging; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Glutamine; Male; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 2001 |
Deamidation of Asn-143 of gamma S crystallin from protein aggregates of the human lens.
Topics: Aging; Asparagine; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Deamination; Glutamine; Humans; Lens, Crystalline; Middle Aged; Molecular Weight | 2001 |
Alternate cadmium exposure differentially affects amino acid metabolism within the hypothalamus, median eminence, striatum and prefrontal cortex of male rats.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Cadmium; Corpus Striatum; Glutamic Acid; Glutamine; Hypothalamus; Male; Median Eminence; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reference Values | 2001 |
Do sex steroids regulate glutamine synthesis with age?
Topics: Adrenalectomy; Aging; Animals; Estradiol; Female; Glutamate-Ammonia Ligase; Glutamine; Muscle, Skeletal; Ovariectomy; Progesterone; Rats; Rats, Wistar; RNA, Messenger | 2002 |
Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Fragile X Mental Retardation Protein; Fragile X Syndrome; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Intellectual Disability; Male; Mice; Mice, Knockout; Models, Animal; Nerve Tissue Proteins; RNA-Binding Proteins; Serotonin; Taurine; Thalamus | 2001 |
Possible role of glutamate, aspartate, glutamine, GABA or taurine on cadmium toxicity on the hypothalamic pituitary axis activity in adult male rats.
Topics: Administration, Oral; Aging; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Cadmium; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hypothalamus; Luteinizing Hormone; Male; Median Eminence; Pituitary Gland; Pituitary Hormones; Prefrontal Cortex; Prolactin; Rats; Rats, Sprague-Dawley; Taurine | 2002 |
Hepatic gluconeogenic capacity from various precursors in young versus old rats.
Topics: Aging; Alanine; Animals; Body Weight; Cell Separation; Cell Survival; Dihydroxyacetone; Fasting; Fructose; Gluconeogenesis; Glucose; Glutamine; Glycerol; Glycogen; Hepatocytes; Lactic Acid; Liver; Male; Oxaloacetates; Pyruvic Acid; Rats; Rats, Inbred F344 | 2002 |
Glutamine and ammonia metabolism in the brains of senescent mice.
Topics: Aging; Ammonia; Animals; Brain; gamma-Glutamyltransferase; Glutamates; Glutaminase; Glutamine; Male; Mice | 1978 |
Glutamate and glutamine in the brain of the neonatal rat during hypercapnia.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Carbon Dioxide; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Hypercapnia; Organ Size; Rats | 1977 |
Renal glutaminase in postnatal and adult rats.
Topics: Aging; Animals; Animals, Newborn; Enzyme Activation; Glutamates; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kidney; Kinetics; Phosphates; Rats | 1975 |
Glutamine-dependent asparagine synthetase in fetal, adult and neoplastic rat tissues.
Topics: Aging; Animals; Animals, Newborn; Aspartate-Ammonia Ligase; Aspartic Acid; Enzyme Activation; Fetus; Glutamine; Hydroxamic Acids; Kinetics; Ligases; Liver; Magnesium; Neoplasms, Experimental; Organ Specificity; Rats | 1975 |
Phosphate activated glutaminase activity and glutamine uptake in primary cultures of astrocytes.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Biological Transport; Brain; Cells, Cultured; Glutaminase; Glutamine; Kinetics; Mice; Phosphates | 1979 |
Dependence of glutamine metabolism and ammonia synthesis on sex in rat kidney slices.
Topics: Aging; Ammonia; Animals; Carbon Dioxide; Castration; Female; Glutamine; In Vitro Techniques; Kidney Cortex; Male; Oxygen Consumption; Rats; Sex Factors | 1978 |
Age dependent amines, amides, and amino acid residues in Drosophila melanogaster.
Topics: Aging; Amides; Amines; Amino Acids; Animals; Chromatography; Drosophila melanogaster; Glutamates; Glutamine; Male; Mathematics | 1976 |
Metabolism of glutamate and related amino acids in the 10-day-old mouse brain: experiments with labelled acetate and beta-hydroxybutyrate.
Topics: Acetates; Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Carbon Radioisotopes; Citric Acid Cycle; Glutamates; Glutamine; Hydroxybutyrates; Mice; Solubility; Tritium | 1976 |
Ontogeny of glutamine transport by rat liver plasma membrane vesicles.
Topics: Aging; Amino Acids; Analysis of Variance; Animals; Animals, Suckling; Biological Transport, Active; Cell Membrane; Choline; Dose-Response Relationship, Drug; Glutamine; Hydrogen-Ion Concentration; Lithium; Liver; Membrane Potentials; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Taurocholic Acid | 1992 |
Chronic neuroleptic treatment: D2 dopamine receptor supersensitivity and striatal glutamatergic transmission.
Topics: Aging; Animals; Antipsychotic Agents; Corpus Striatum; Ergolines; Glutamine; Haloperidol; Parasympathomimetics; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, GABA-A; Receptors, Muscarinic; Synaptic Transmission; Time Factors | 1992 |
Lipofuscin-like fluorophores can result from reactions between oxidized ascorbic acid and glutamine. Carbonyl-protein cross-linking may represent a common reaction in oxygen radical and glycosylation-related ageing processes.
Topics: Aging; Ascorbic Acid; Cross-Linking Reagents; Fluorescent Dyes; Free Radicals; Glutamine; Glycosylation; Hydrogen-Ion Concentration; In Vitro Techniques; Lipofuscin; Oxidation-Reduction; Schiff Bases | 1992 |
Accumulation and localization of two adult acinar cell secretory proteins during development of the rat submandibular gland.
Topics: Aging; Animals; Glutamates; Glutamic Acid; Glutamine; Glycoproteins; Microscopy, Electron; Mucins; Phenotype; Proteins; Rats; Submandibular Gland; Tissue Distribution | 1991 |
[Excitatory amino acids, the cerebral cortex and aging: a new perspective].
Topics: Age Factors; Aging; Amino Acids; Animals; Cerebral Cortex; Glutamine; Humans; Hypoxia, Brain; Nerve Degeneration; Neurochemistry; Neurotransmitter Agents | 1991 |
Metabolic changes of several adipose depots as caused by aging.
Topics: Adipose Tissue; Aging; Animals; Citrate (si)-Synthase; Citric Acid Cycle; Energy Metabolism; Glucosephosphate Dehydrogenase; Glutaminase; Glutamine; Lipid Mobilization; Lipoprotein Lipase; Male; Pentose Phosphate Pathway; Rats | 1991 |
Dietary arginine supplementation does not enhance lymphocyte proliferation or interleukin-2 production in young and aged rats.
Topics: Aging; Alanine; Animals; Arginine; Body Weight; Citrulline; Concanavalin A; Diet; Glutamine; Interleukin-2; Lymphocyte Activation; Male; Organ Size; Ornithine; Phytohemagglutinins; Pokeweed Mitogens; Rats; Rats, Inbred F344; Spleen | 1991 |
Development of L-glutamine-stimulated electroneutral sodium absorption in piglet jejunum.
Topics: Aging; Animals; Animals, Newborn; Chlorides; Electric Conductivity; Electrophysiology; Glutamine; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mannitol; Muscle Development; Muscle, Smooth; Phenylalanine; Sodium; Swine | 1990 |
Memory deficits of aged male rats can be improved by pyrimidine nucleosides and n-acetyl-glutamine.
Topics: Aging; Animals; Behavior, Animal; Cytidine; Glutamine; Male; Memory Disorders; Rats; Rats, Inbred Strains; Uridine | 1990 |
High-affinity glutamine uptake of the rat hippocampus during postnatal development: a quantitative autoradiographic study.
Topics: Aging; Amino Acids, Diamino; Animals; Diazooxonorleucine; Glutamine; Hippocampus; Male; Rats; Rats, Inbred Strains | 1990 |
Maturational changes in glutamine transport by rat jejunal brush border membrane vesicles.
Topics: Aging; Animals; Animals, Newborn; Animals, Suckling; Glutamine; Hydrogen-Ion Concentration; Jejunum; Lithium; Membrane Potentials; Microvilli; Osmolar Concentration; Potassium; Rats; Rats, Inbred Strains; Sodium; Tritium | 1990 |
Developmental changes in glutamine transport by rat jejunal basolateral membrane vesicles.
Topics: Aging; Amino Acids; Animals; Animals, Suckling; Basement Membrane; Biological Transport, Active; Glutamine; Hydrogen-Ion Concentration; Jejunum; Kinetics; Lithium; Male; Membrane Potentials; Osmolar Concentration; Potassium; Rats; Sodium; Temperature; Weaning | 1990 |
Age-related changes in muscle ammonia detoxification potential in exhausted rats.
Topics: Aging; Ammonia; AMP Deaminase; Animals; Glutamate Dehydrogenase; Glutamine; Male; Muscle Contraction; Muscle Proteins; Muscles; Physical Exertion; Rats; Urea | 1987 |
Maximal activities of glutaminase, citrate synthase, hexokinase, phosphofructokinase and lactate dehydrogenase in skin of rats and mice at different ages.
Topics: Aging; Animals; Burns; Citrate (si)-Synthase; DNA Repair; Glutaminase; Glutamine; Glycolysis; Hexokinase; L-Lactate Dehydrogenase; Lymphocytes; Mice; Phosphofructokinase-1; Purines; Pyrimidines; Rats; Skin; Wound Healing | 1989 |
Effect of protein malnutrition on the composition of submandibular glands of aged rats.
Topics: Aging; Animals; DNA; Glutamine; Kallikreins; Male; Mucins; Nutrition Disorders; Nutritional Status; Organ Size; Protein Deficiency; Rats; Rats, Inbred Strains; Salivary Proteins and Peptides; Spectrophotometry; Submandibular Gland | 1989 |
Changes with aging in the levels of amino acids in rat CNS structural elements. I. Glutamate and related amino acids.
Topics: Aging; Animals; Aspartic Acid; Brain; Brain Mapping; Brain Stem; Cerebellar Cortex; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hypothalamus; Limbic System; Male; Rats | 1989 |
Aspartate metabolism in rats during aging.
Topics: Aging; Animals; Aspartic Acid; Brain; Carbon Dioxide; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1985 |
Utilization of plasma fatty acid in rat brain: distribution of [14C]palmitate between oxidative and synthetic pathways.
Topics: Aging; Amino Acids; Animals; Brain; Gangliosides; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lipid Metabolism; Male; Nerve Tissue Proteins; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phospholipids; Rats; Rats, Inbred F344; Tissue Distribution | 1987 |
Competition of glycerol with other oxidizable substrates in rat brain.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Brain; Carbon Dioxide; Female; Glucose; Glutamine; Glycerol; Hydroxybutyrates; In Vitro Techniques; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1986 |
Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors.
Topics: Adult; Aging; Alzheimer Disease; Calcium; Cells, Cultured; DNA; Female; Glucose; Glutamine; Humans; Male; Middle Aged; Mitochondria; Protein Biosynthesis; Skin | 1986 |
Stimulation of the hexose monophosphate pathway by pyrroline-5-carboxylate reductase in the lens.
Topics: Aging; Animals; Female; Glucose; Glutamine; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains | 1985 |
Nutritional and metabolic responses to arginine deficiency in carnivores.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Carnivora; Cats; Citrulline; Dogs; Glutamine; Intestinal Mucosa; Kidney; Liver; Muscles; Nutritional Requirements; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Rats; Species Specificity; Urea | 1985 |
Glutamate and glutamine in the brain of the rat during early postnatal life: influence of hypercapnia.
Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Dioxide; Female; Glutamates; Glutamine; Hypercapnia; Pregnancy; Rats | 1973 |
Distribution of glutamine hexosephosphate aminotransferase in rat tissues; changes with state of differentiation.
Topics: Aging; Animals; Brain; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Cell Differentiation; Female; Fetus; Fructosephosphates; Glucose; Glutamine; Intestines; Kidney; Kidney Neoplasms; Kinetics; Lactation; Liver; Liver Neoplasms; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Muscles; Myocardium; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Salivary Glands; Transaminases | 1973 |
Emergency care for acute poisoning with phosphororganic compounds.
Topics: Adolescent; Adult; Aged; Aging; Alanine; Amino Acids; Child; Cystine; Female; Glutamine; Growth; Humans; Male; Middle Aged; Sex Factors; Statistics as Topic | 1973 |
Relationship of protein metabolism to senescence of corn (Zea mays L.) stalk parenchyma, cob parenchyma and first developed leaf tissues.
Topics: Aging; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cell Count; Chromatography; Dactinomycin; Glutamine; Leucine; Models, Biological; Ornithine; Phenylalanine; Plant Proteins; Plants; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Threonine; Time Factors; Tyrosine | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Effect of undernutrition on amino acid compartimentation in the developing rat brain.
Topics: Aging; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Body Weight; Brain; Carbon Radioisotopes; Chromatography, Ion Exchange; Citric Acid Cycle; Glutamates; Glutamine; Leucine; Organ Size; Protein Deficiency; Rats; Statistics as Topic | 1974 |
Free amino acids in developing rat retina.
Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine | 1974 |
The metabolism of (14C) glucose by the brains of suckling rats intoxicated with inorganic lead.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Body Weight; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Chromatography, Ion Exchange; Female; Glucose; Glutamates; Glutamine; Lactation; Lead Poisoning; Pregnancy; Rats; Statistics as Topic | 1974 |
[Urinary amino acids in children and adults with normal metabolism].
Topics: Adolescent; Aging; Alanine; Amino Acids; Child; Child, Preschool; Chromatography, DEAE-Cellulose; Chromatography, Paper; Circadian Rhythm; Female; Glutamates; Glutamine; Glycine; Humans; Infant; Male; Muscles | 1972 |
Comparison of cytoplasmic glycerol-3-phosphate dehydrogenase from rat liver and muscle.
Topics: Acetates; Acrylamides; Aging; Amino Acids; Animals; Body Weight; Cellulose; Cytoplasm; Electrophoresis; Electrophoresis, Disc; Glutamates; Glutamine; Glycerolphosphate Dehydrogenase; Isoelectric Focusing; Isoenzymes; Liver; Methionine; Muscles; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Time Factors | 1971 |
The effect of catechol amines on free amino acids in rat heart and other organs.
Topics: Aging; Alanine; Amino Acids; Animals; Arginine; Epinephrine; Female; Glutamates; Glutamine; Heart; Liver; Metabolism; Myocardium; Norepinephrine; Ornithine; Rats; Reserpine; Time Factors | 1969 |
Effect of acute acid loading on urinary acid excretion by the aging human kidney.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Aging; Amino Acids; Ammonia; Ammonium Chloride; Bicarbonates; Glomerular Filtration Rate; Glutamine; Humans; Hydrogen-Ion Concentration; Kidney; Kidney Tubules; Male; Middle Aged | 1968 |