glutamine has been researched along with Acute Lymphoid Leukemia in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 12 (40.00) | 24.3611 |
| 2020's | 7 (23.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bakkali, A; Brigitha, LJ; Pieters, R; Struys, EA; van der Sluis, IM | 1 |
| Dzharov, V; Petrie, K; Sarafian, V; Sbirkov, Y; Schenk, T; Vergov, B | 1 |
| Aguera, K; Andrivon, A; Blachier, J; Châlons-Cottavoz, M; Cleret, A; Fanjat, JM; Gallix, F; Gay, F; Gil, C; Guerin, N; Horand, F; Laperrousaz, B; Piedrahita, D; Rama, N; Rossignol, R; Tavernier, F; Vidault, L | 1 |
| Altintas, B; Eldem, I; Langley, R; Lee, A; Nguyen, H; Shinawi, M; Willis, D | 1 |
| Irawan, R; Pratama, A; Prihaningtyas, R; Ugrasena, I; Widjaja, NA | 1 |
| Bodineau, C; Bouchecareilh, M; Calvo, J; Durán, RV; Falcon-Perez, JM; Fuentes, P; Galmar, O; Khatib, AM; Murdoch, PDS; Muzotte, E; Nguyen, TL; Nokin, MJ; Pasquet, JM; Pflumio, F; Priault, M; Redonnet-Vernhet, I; Rezvani, HR; Richard, E; Rousseau, B; Soubeyran, P; Terés, S; Tomé, M; Toribio, ML; Uzan, B; van Liempd, S | 1 |
| Bielawski, JP; Cohen, A; Connors, J; Dunn, KA; Forbrigger, Z; Kulkarni, K; Langille, MGI; MacDonald, T; Penny, SL; Rahman, M; Stadnyk, AW; Van Limbergen, J | 1 |
| Chang, YH; Chao, YH; Chiou, YH; Hsu, MC; Peng, CT; Wu, HP; Wu, KH; Yu, MS | 1 |
| Ardalan, N; Khavari-Nejad, RA; Mirzaie, S; Sepahi, AA | 1 |
| Björklund, AC; Daskalaki, E; Dyczynski, M; Gallart-Ayala, H; Grandér, D; Janssen, J; Lehtiö, J; Nilsson, R; Tamm, KP; Vesterlund, M; Wheelock, CE; Zachariadis, V | 1 |
| Almeida, RV; Bon, EPDS; Ferrara, MA; Gregório Alves Fontão, AP; Jurgilas, PB; Lopes, W; Nascimento, HJ; Sampaio, ALF; Santos, BAFD; Torres, FAG | 1 |
| Al-Abodi, HR; Al-Marzoqi, AH; Alghanimi, YK; Fattahi, A; Ghasemian, A; Kadhum, SA; Shokouhi Mostafavi, SK | 1 |
| Albertsen, BK; Frandsen, TL; Henriksen, LT; Nersting, J; Raja, RA; Rosthøj, S; Schrøder, H | 1 |
| Asselin, B; Rizzari, C | 1 |
| Fujimura, T; Isobe, Y; Kaga, N; Komatsu, N; Miyazono, K; Ono, A; Sasaki, M; Sugimoto, K; Suzuki, HI; Taka, H | 1 |
| Bu, Y; Dai, J; Han, Y; Sun, X; Wang, J; Xiao, Y; Yang, Q; Zhang, F; Zhu, Y | 1 |
| Carr, D; Dallapozza, L; Earl, JW; Eslick, AE; Misra, A; Nath, CE | 1 |
| Bussolati, O; Chiarelli, LR; Covini, D; Digilio, R; Pasquetto, MV; Scotti, C; Tardito, S; Valentini, G | 1 |
| Doble, M; Ln, R; Pulicherla, KK; Rekha, VP | 1 |
| Attarbaschi, A; Dworzak, MN; Haas, OA; Hochreiter, D; Hutter, C; Kasper, DC; Kornmüller, R; Mann, G; Pichler, H; Pötschger, U; Steiner, M | 1 |
| Halonen, P; Mäkipernaa, A; Salo, MK; Schmiegelow, K | 1 |
| Avramis, VI; Felgenhauer, JL; Hawkins, DS; Holcenberg, JS; Panosyan, EH; Park, JR; Thomson, BG | 1 |
| Bukac, J; Horacek, J; Kmonicek, M; Maly, J; Sykorova, A; Zak, P | 1 |
| Sugimura, K; Sukemori, S | 2 |
| Boehlein, SK; Dribben, AB; Parr, IB; Richards, NG; Schuster, SM | 1 |
| Ahlke, E; Boos, J; Jürgens, H; Nowak-Göttl, U; Ritter, J; Schulze-Westhoff, P; Verspohl, EJ; Werber, G; Würthwein, G | 1 |
| Aslanian, AM; Kilberg, MS | 1 |
| Catovsky, D; Gill, R; Levi, S; Marshall, CJ; Matutes, E; Urbano-Ispizua, A; Wiedemann, LM | 1 |
| Jansen, S; Linkesch, W; Mödder, B; Ollenschläger, G; Roth, E; Simmel, A | 1 |
3 review(s) available for glutamine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Bacterial l-asparaginases for cancer therapy: Current knowledge and future perspectives.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Glutamine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombination, Genetic | 2019 |
Asparaginase pharmacokinetics and implications of therapeutic drug monitoring.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Clinical Trials as Topic; Drug Monitoring; Enzyme Activation; Glutamine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2015 |
Expanding targets for a metabolic therapy of cancer: L-asparaginase.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Drug Delivery Systems; Glutaminase; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
3 trial(s) available for glutamine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Efficacy Oral Glutamine to Prevent Oral Mucositis and Reduce Hospital Costs During Chemotherapy in Children with Acute Lymphoblastic Leukemia.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Child; Child, Preschool; Female; Follow-Up Studies; Glutamine; Hospital Costs; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Stomatitis | 2020 |
Application of Glutamine-enriched nutrition therapy in childhood acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Weight; Child; Child, Preschool; Creatinine; Female; Glutamine; Humans; Hydroxyproline; Infant; Killer Cells, Natural; Male; Nutritional Status; Nutritional Support; Prealbumin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinol-Binding Proteins; Serum Albumin | 2016 |
A randomized, double blind comparative study of prophylactic parenteral nutritional support with or without glutamine in autologous stem cell transplantation for hematological malignancies -- three years' follow-up.
Topics: Adolescent; Adult; Aged; Diet; Dietary Supplements; Disease-Free Survival; Double-Blind Method; Female; Glutamine; Hematologic Neoplasms; Hodgkin Disease; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Parenteral Nutrition; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Transplantation; Survival Rate; Transplantation, Autologous | 2005 |
24 other study(ies) available for glutamine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Depletion of d- and l-asparagine in cerebrospinal fluid in acute lymphoblastic leukemia during PEGasparaginase therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Child; Child, Preschool; Glutamine; Humans; Infant; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Targeting Glutaminolysis Shows Efficacy in Both Prednisolone-Sensitive and in Metabolically Rewired Prednisolone-Resistant B-Cell Childhood Acute Lymphoblastic Leukaemia Cells.
Topics: Child; Drug Resistance, Neoplasm; Glucocorticoids; Glutamine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone | 2023 |
L-asparaginase anti-tumor activity in pancreatic cancer is dependent on its glutaminase activity and resistance is mediated by glutamine synthetase.
Topics: Asparaginase; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2023 |
Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Glutamine; Humans; Hyperammonemia; Phenylbutyrates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sodium Benzoate; Treatment Outcome | 2023 |
Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia.
Topics: Animals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Glutamate-Ammonia Ligase; Glutamine; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred NOD; Mice, Transgenic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptor, Notch1; Signal Transduction | 2021 |
Gut bacterial gene changes following pegaspargase treatment in pediatric patients with acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Genes, Bacterial; Glutamic Acid; Glutamine; Humans; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2021 |
Effectiveness of Parenteral Glutamine on Methotrexate-induced Oral Mucositis in Children with Acute Lymphoblastic Leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Glutamine; Humans; Male; Methotrexate; Parenteral Nutrition; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stomatitis | 2017 |
Novel mutant of Escherichia coli asparaginase II to reduction of the glutaminase activity in treatment of acute lymphocytic leukemia by molecular dynamics simulations and QM-MM studies.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Catalytic Domain; Drug Design; Escherichia coli Proteins; Glutamine; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation, Missense; Point Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Protein Conformation; Quantum Theory; Substrate Specificity; Thermodynamics | 2018 |
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Glucocorticoids; Glutamine; Glycolysis; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2018 |
Expression, purification, and characterization of asparaginase II from Saccharomyces cerevisiae in Escherichia coli.
Topics: Antineoplastic Agents; Asparaginase; Asparagine; Bacterial Proteins; Cell Line, Tumor; Cloning, Molecular; Escherichia coli; Gene Expression; Glutamine; Humans; Molecular Weight; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Saccharomyces cerevisiae | 2019 |
Cerebrospinal fluid asparagine depletion during pegylated asparaginase therapy in children with acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Child; Child, Preschool; Drug Administration Schedule; Drug Monitoring; Female; Glutamine; Humans; Infant; Injections, Intramuscular; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Specimen Handling | 2014 |
A clinically attainable dose of L-asparaginase targets glutamine addiction in lymphoid cell lines.
Topics: Antineoplastic Agents; Asparaginase; Cell Line, Tumor; Chromatography, Gas; Flow Cytometry; Glutamine; Humans; Jurkat Cells; Lymphoma, Mantle-Cell; Mass Spectrometry; Membrane Potential, Mitochondrial; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2015 |
An isocratic fluorescence HPLC assay for the monitoring of l-asparaginase activity and l-asparagine depletion in children receiving E. colil-asparaginase for the treatment of acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli Proteins; Fluorescence; Glutamic Acid; Glutamine; Homoserine; Humans; Least-Squares Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2009 |
In silico engineering of L-asparaginase to have reduced glutaminase side activity for effective treatment of acute lymphoblastic leukemia.
Topics: Asparaginase; Asparagine; Catalytic Domain; Child; Computer Simulation; Drug Design; Glutaminase; Glutamine; Humans; Ligands; Mutagenesis, Site-Directed; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Engineering | 2011 |
Asparagine and aspartic acid concentrations in bone marrow versus peripheral blood during Berlin-Frankfurt-Münster-based induction therapy for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Child; Child, Preschool; Daunorubicin; Drug Administration Schedule; Female; Glutamic Acid; Glutamine; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Time Factors; Treatment Outcome; Vincristine | 2012 |
Investigation of the mechanisms of therapy-related hypoglycaemia in children with acute lymphoblastic leukaemia.
Topics: Adolescent; Alanine; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Carnitine; Child; Child, Preschool; Female; Glutamine; Humans; Hypoglycemia; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Child; Child, Preschool; Delayed-Action Preparations; Female; Glutamine; Humans; Immunophenotyping; Male; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2004 |
Inhibition of cultured leukemia cell growth by enhanced adriamycin cytotoxicity with reduction of glutamine or asparagine level in medium.
Topics: Animals; Asparagine; Cell Division; Culture Media; Doxorubicin; Glutamine; Humans; Leukemia P388; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proline; Tumor Cells, Cultured | 1994 |
Mapping the aspartic acid binding site of Escherichia coli asparagine synthetase B using substrate analogs.
Topics: Alkylation; Antineoplastic Agents; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Bacterial Proteins; Binding Sites; Drug Design; Enzyme Inhibitors; Escherichia coli; Glutamine; Humans; Isoenzymes; Kinetics; Molecular Conformation; Molecular Structure; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 1996 |
Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Child, Preschool; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1996 |
Extracellular glutamine level reduction enhances 5-fluorouracil cytotoxicity.
Topics: Amino Acids; Animals; Asparagine; Cell Count; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Humans; Leukemia; Leukemia P388; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1998 |
Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells.
Topics: Amino Acids; Asparaginase; Aspartate-Ammonia Ligase; Aspartic Acid; Biological Transport; Cell Division; Cell Membrane; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Flow Cytometry; Glutamate-Ammonia Ligase; Glutamine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA; RNA, Messenger; Substrate Specificity; Tumor Cells, Cultured | 2001 |
Low frequency of ras oncogene mutations in Philadelphia-positive acute leukemia and report of a novel mutation H61 Leu in a single case.
Topics: Codon; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamine; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Mutation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transcriptional Activation | 1992 |
Asparaginase-induced derangements of glutamine metabolism: the pathogenetic basis for some drug-related side-effects.
Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Cell Count; Blood Chemical Analysis; Female; Glutamine; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1988 |