glutaminase and Myocardial-Infarction

In experiments on 105 dogs it was found that at the onset and in the course of extensive myocardial infarction there regularly occur a specific set of shifts in the protein and nuclein metabolism in skeletal muscles. Besides changes reflecting a certain decrease in the functional capacity of muscles there also appear metabolic reactions of compensatory nature. Changes in nitrogen metabolism in striated muscles are most pronounced in the formation period of myocardial infarct but partially persist during the organization stages, some of them up to a period of a whole month. The intensities of changes are mostly expressed by values 20-35% higher than the initial ones, but in some indicators the alterations are still more intense.

Topics: Actomyosin; Adenosine Monophosphate; Alanine Transaminase; Amino Acids; Aminohydrolases; Ammonia; Animals; Aspartate Aminotransferases; Deoxyribonucleases; DNA; Dogs; Glutaminase; Hindlimb; Muscle Proteins; Muscles; Myocardial Infarction; Nucleotidases; Nucleotides; Ribonucleases; RNA; Urea

Topics: Adenosine Triphosphatases; Animals; Arginase; Aspartate Aminotransferases; Dogs; Glucose; Glutaminase; Glutamine; Heart; Insulin; Kidney; Liver; Muscle Proteins; Myocardial Infarction; Myocardium; Nitrogen; Proteins; Urea

Topics: Clinical Enzyme Tests; Electron Transport Complex IV; Glutaminase; Histocytochemistry; Hydroxybutyrate Dehydrogenase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Myocardial Infarction; Myocardium; NAD; NADP; Succinate Dehydrogenase