glutaminase has been researched along with DNA-Virus-Infections* in 1 studies
1 other study(ies) available for glutaminase and DNA-Virus-Infections
| Article | Year |
|---|---|
Glutamine Metabolism in Both the Oxidative and Reductive Directions Is Triggered in Shrimp Immune Cells (Hemocytes) at the WSSV Genome Replication Stage to Benefit Virus Replication.
White spot syndrome virus (WSSV) is the causative agent of a shrimp disease that has caused huge global economic losses. Although its pathogenesis remains poorly understood, it has been reported that in the shrimp immune cells (hemocytes) targeted by WSSV, the virus triggers both the Warburg effect and glutamine metabolism at the WSSV genome replication stage (12 h post infection). Glutamine metabolism follows two pathways: an oxidative pathway mediated by α-KGDH (α-ketoglutarate dehydrogenase) and an alternative reductive pathway mediated by IDH1 and IDH2 (isocitrate dehydrogenase 1 and 2). Here we used isotopically labeled glutamine ([U- Topics: Animals; DNA Virus Infections; Genome, Viral; Glutaminase; Glutamine; Hemocytes; Isocitrate Dehydrogenase; Ketoglutarate Dehydrogenase Complex; Oxidation-Reduction; Penaeidae; Virus Replication; White spot syndrome virus 1 | 2019 |