glutaminase and Colitis

glutaminase has been researched along with Colitis* in 2 studies

Other Studies

2 other study(ies) available for glutaminase and Colitis

Article	Year
Spontaneous colitis in IL-10-deficient mice was ameliorated via inhibiting glutaminase1. Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8 Topics: Adult; Animals; Colitis; Crohn Disease; Female; Glutaminase; Humans; Interleukin-10; Intestines; Lymphocyte Subsets; Male; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Sulfides; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thiadiazoles	2019
Pathological features of glutaminase toxicity. British journal of experimental pathology, 1980, Volume: 61, Issue:2 In an investigation of the toxicity of the anti-tumour enzyme glutaminase Rhesus monkeys, marmosets, rabbits and mice were given various doses of chemically modified glutaminase parenterally. The enzyme induced diarrhoea and dysentery and at all but the lowest doses caused illness which was fatal within 10 days. Pathological lesions produced were hepatic lipidosis and glycogen accumulation, and, in the primates, acute necrotizing colitis. Topics: Animals; Callitrichinae; Chemical and Drug Induced Liver Injury; Colitis; Diarrhea; Female; Glutaminase; Haplorhini; Intestines; Lipidoses; Liver; Macaca mulatta; Male; Mice; Rabbits	1980

Article

Year

Spontaneous colitis in IL-10-deficient mice was ameliorated via inhibiting glutaminase1.

Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8

Topics: Adult; Animals; Colitis; Crohn Disease; Female; Glutaminase; Humans; Interleukin-10; Intestines; Lymphocyte Subsets; Male; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Sulfides; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thiadiazoles

2019

Pathological features of glutaminase toxicity.

British journal of experimental pathology, 1980, Volume: 61, Issue:2

In an investigation of the toxicity of the anti-tumour enzyme glutaminase Rhesus monkeys, marmosets, rabbits and mice were given various doses of chemically modified glutaminase parenterally. The enzyme induced diarrhoea and dysentery and at all but the lowest doses caused illness which was fatal within 10 days. Pathological lesions produced were hepatic lipidosis and glycogen accumulation, and, in the primates, acute necrotizing colitis.

Topics: Animals; Callitrichinae; Chemical and Drug Induced Liver Injury; Colitis; Diarrhea; Female; Glutaminase; Haplorhini; Intestines; Lipidoses; Liver; Macaca mulatta; Male; Mice; Rabbits

1980