glutamic acid and Schizophrenia

glutamic acid has been researched along with Schizophrenia in 687 studies

Research

Studies (687)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (3.06)	18.7374
1990's	64 (9.32)	18.2507
2000's	207 (30.13)	29.6817
2010's	291 (42.36)	24.3611
2020's	104 (15.14)	2.80

Authors

Authors	Studies
Hung, CC; Lane, HY; Lin, CH	1
de la Fuente-Sandoval, C; Graff-Guerrero, A; Honda, S; Hondo, N; Iwata, Y; Kinjo, M; Mimura, M; Mori, Y; Moriguchi, S; Nakahara, K; Nakahara, T; Nakajima, S; Noda, Y; Plitman, E; Segawa, H; Tarumi, R; Tsugawa, S; Uchida, H; Ueno, F; Wada, M; Watanabe, H; Yoshida, K	1
Danielmeier, C; Dixon, BJ; Kumar, J	1
Chen, X; He, Y; Ma, X; Ouyang, L; Yuan, L; Zheng, W	1
Carter, CS; Maddock, RJ; Smucny, J	2
Abdullah, U; Ali, Z; Asif, M; Baig, SM; Farooq, M; Fatima, A; Mang, Y; Mehrjouy, MM; Tommerup, N	1
Dedic, N; Dworak, H; Howes, OD; Rutigliano, G; Zeni, C	1
Javitt, DC; Kantrowitz, JT	2
Abdullah, M; Chen, KC; Huang, LC; Lin, SH; Tseng, HH; Yang, YK	1
Bansal, S; Corlett, P; Culbreth, A; Dutterer, J; Erickson, M; Gaston, F; Gold, J; Kenney, J; Leptourgos, P; Powers, A; Rowland, LM; Suthaharan, P; Waltz, J; Wijtenburg, SA	1
Conn, PJ; Dogra, S	1
Fujimori, H; Hara, H; Mizoguchi, T; Nakamura, S; Ohba, T; Shimazawa, M; Shinohara, M	1
Buck, SA; Freyberg, Z; Logan, RW; Quincy Erickson-Oberg, M	1
Cai, XL; Chan, RCK; Cheung, EFC; Huang, J; Lui, SSY; Madsen, KH; Møller, A; Pu, CC; Wang, Y; Xue, R; Yu, X; Zhou, SZ	1
Green, MF; Hellemann, G; Lee, J; Maddock, RJ; Marder, SR; Yang, YS; Zhang, H	1
Cieślik, P; Wierońska, JM	1
Bauminger, H; Gaisler-Salomon, I	1
Austin, MC; Barone, A; Ciccarelli, M; de Bartolomeis, A; Iasevoli, F; Mazza, B; Vellucci, L	1
Blazer, A; Calabro, FJ; Ferrarelli, F; Foran, W; Hetherington, HP; Luna, B; Mayeli, A; Perica, M; Sarpal, DK; Sonnenschein, SF; Yushmanov, VE	1
Boksha, IS; Burbaeva, GS; Chen, L; Dai, X; Dong, Y; Hou, Y; Lv, X; Omel'chenko, MA; Prokhorova, TA; Savushkina, OK; Tereshkina, EB; Vorobieva, EA; Wang, L; Zhong, G	1
McCullumsmith, RE; Rowland, LM	1
Alijanpour, S; Ghafouri-Fard, S; Miryounesi, M	1
Ahmad, I; Bhardwaj, T; Somvanshi, P	1
Casetta, C; Deakin, B; Drake, R; Egerton, A; Griffiths, K; Howes, OD; Kassoumeri, L; Khan, S; Lankshear, S; Lees, J; Lewis, S; MacCabe, JH; Mikulskaya, E; Millgate, E; Oloyede, E; Pollard, R; Rich, N; Segev, A; Sendt, KV	1
Bustillo, JR; Kruse, AO	1
Altynbekov, KS; Asadullin, AR; Gayduk, AJ; Khasanova, AK; Markina, EA; Nasyrova, RF; Petrova, MM; Shipulin, GA; Shnayder, NA	1
Egerton, A; Hedges, EP; Modinos, G; Murray, RM; Onwordi, EC; Wall, MB; Zahid, U	1
Blazer, A; Calabro, FJ; Ferrarelli, F; Foran, W; Hetherington, HP; Luna, B; Mayeli, A; Perica, M; Sarpal, DK; Sonnenschein, SF; Wilson, JD; Yushmanov, VE	1
Cheng, MC; Hsu, SH; Hu, TM; Lin, KH; Tsai, HY	1
Simmonite, M; Taylor, SF; Welsh, RC; Yao, B	1
Arbelo, N; García-Rizo, C; Gassó, P; Gómez, M; Madero, S; Martínez-Pinteño, A; Mas, S; Morén, C; Parellada, E; Rodríguez, N; Treder, N	1
Ahmed, S; Anwar, S; Malik, JA; Shaikh, MF; Thotapalli, L; Yaseen, Z	1
Guo, J; Rothman, DL; Small, SA	1
Curic, S; Haaf, M; Leicht, G; Mulert, C; Rauh, J; Steinmann, S	1
Aleman, A; Ashley, S; Beck, K; Block, W; Bloemen, OJN; Borgan, F; Boules, C; Bustillo, JR; Capizzano, AA; Coughlin, JM; David, A; de la Fuente-Sandoval, C; Demjaha, A; Dempster, K; Do, KQ; Du, F; Egerton, A; Falkai, P; Galińska-Skok, B; Gallinat, J; Gasparovic, C; Ginestet, CE; Goto, N; Graff-Guerrero, A; Ho, BC; Howes, O; Jauhar, S; Jeon, P; Kato, T; Kaufmann, CA; Kegeles, LS; Keshavan, MS; Kim, SY; King, B; Kunugi, H; Lauriello, J; León-Ortiz, P; Liemburg, E; McCutcheon, RA; McGuire, P; Mcilwain, ME; Merritt, K; Modinos, G; Mouchlianitis, E; Nakamura, J; Nenadic, I; Öngür, D; Ota, M; Palaniyappan, L; Pantelis, C; Patel, T; Plitman, E; Posporelis, S; Purdon, SE; Reichenbach, JR; Renshaw, PF; Reyes-Madrigal, F; Russell, BR; Sawa, A; Schaefer, M; Shungu, DC; Smesny, S; Stanley, JA; Stone, J; Szulc, A; Taylor, R; Thakkar, KN; Théberge, J; Tibbo, PG; van Amelsvoort, T; Walecki, J; Williamson, PC; Wood, SJ; Xin, L; Yamasue, H	1
Carlson, M; Choo, TH; De Baun, HM; Dias, E; Gangwisch, J; Girgis, RR; Iosifescu, DV; Kantrowitz, JT; Kegeles, LS; Mayer, MR; Medalia, A; Saperstein, AM; Sehatpour, P; Shope, C; Sobeih, T; Wall, MM	1
Amirsadri, A; Chowdury, A; Daugherty, AM; Diwadkar, VA; Haddad, L; Khatib, D; Rajan, U; Richter Gorey, C; Stanley, JA; Thomas, P	1
Bojesen, KB; Glenthøj, BY; Jessen, K; Johansen, LB; Nielsen, MØ; Rostrup, E; Sigvard, A; Tangmose, K	1
Graham, JWC; Jeon, P; Palaniyappan, L; Théberge, J	1
Deakin, B; Drake, R; Egerton, A; Fenn-Moltu, S; Howes, OD; Lawrie, SM; Lewis, S; MacCabe, JH; Mondelli, V; Nikkheslat, N; Walters, JTR	1
Matrisciano, F	1
Anand, R; Chinellato, G; Hartman, RD; Roy, A; Turolla, A	1
Barone, A; Buonaguro, EF; Ciccarelli, M; D'Urso, G; de Bartolomeis, A; De Simone, G; Fornaro, M; Iasevoli, F; Vellucci, L	1
Barker, GJ; Deakin, B; Egerton, A; Griffiths, K; Lawrie, SM; Lewis, S; Lythgoe, DJ; MacCabe, JH; Pardiñas, AF; Semple, S; Singh, K; Smart, SE; Walters, JTR; Williams, SR	1
Garip, B; Kayir, H	1
Gewirtz, JC; Matveeva, TM; Miller, RF; Pisansky, MT; Young, A	1
Fukuda, Y; Gallinat, J; Gleich, T; Heinz, A; Kaminski, J; Katthagen, T; Schlagenhauf, F	1
Chen, H; Gaston, FE; Klingaman, EA; Korenic, SA; Rowland, LM; Wickwire, EM; Wijtenburg, SA	1
Bitzer-Quintero, OK; Domínguez-Díaz, C; Pérez-Carranza, GA; Ramírez-Jirano, LJ; Velasco-Ramírez, SF	1
Bless, JJ; Craven, AR; Ersland, L; Grüner, R; Hjelmervik, H; Hugdahl, K; Johnsen, E; Kompus, K; Kroken, RA; Løberg, EM; Sinceviciute, I	1
Dechent, P; Ertl-Wagner, B; Falkai, P; Ghaseminejad, F; Hasan, A; Helms, G; Karali, T; Keeser, D; Keller-Varady, K; Malchow, B; Maurus, I; Rauchmann, BS; Schmitt, A; Schneider-Axmann, T; Takahashi, S; Wobrock, T	1
Brucato, G; Feng, X; First, MB; Girgis, RR; Guo, J; Lieberman, JA; Provenzano, FA; Rothman, DL; Sigmon, HC; Small, SA; Wall, MM	1
Chakravarty, MM; Chavez, S; Fujii, S; Graff-Guerrero, A; Honda, S; Matsui, M; Matsushita, K; Mimura, M; Miyazaki, T; Nakajima, S; Noda, Y; Plitman, E; Remington, G; Sawada, K; Tarumi, R; Tsugawa, S; Uchida, H; Wada, M	1
Provenzano, FA	1
Benesh, JL; Meador-Woodruff, JH; Mueller, TM	1
Fukuyama, K; Murata, M; Okada, M; Okubo, R; Shiroyama, T	1
Dean, B; Gibbons, A; Parkin, GM; Udawela, M	1
Birur, B; Jindal, RD; Kraguljac, NV; Lahti, AC; Luker, A; Morgan, CJ; Reid, MA; VerHoef, L	1
Kraguljac, NV; Lahti, AC; Reddy-Thootkur, M	1
Brown, EE; Caravaggio, F; Chakravarty, MM; Chan, N; Gerretsen, P; Graff-Guerrero, A; Hahn, M; Iwata, Y; Kim, J; Nakajima, S; Plitman, E; Remington, G; Shah, P; Torres, E	1
Benyamina, A; Martelli, C; Petillion, A; Romeo, B	1
Dempster, K; Jeon, P; MacKinley, M; Palaniyappan, L; Théberge, J; Williamson, P	1
Jacob, A; Kumar, V; Manchegowda, S; Rao, NP	1
Bartha, R; Das, T; Dempster, K; Jeon, P; Limongi, R; Mackinley, M; Palaniyappan, L; Théberge, J; Wong, D	1
Gurler, D; Kraguljac, NV; Lahti, AC; Martin, C; Tennant, B; Ver Hoef, L; White, DM	1
Corcoran, M; Dauvermann, MR; Hall, J; Hawkins, EL; Lawrie, SM; O'Hora, D; Whalley, HC	1
Bustillo, JR; Gasparovic, C; Jones, T; Lenroot, R; Maudsley, AA; Mayer, EG; Tohen, M; Upston, J	1
Kondo, HM; Lin, IF	1
Horita, N; Kubota, M; Moriguchi, S; Nakajima, S; Takahata, K	1
Fan, YY; Sun, LH; Wang, X; Zheng, HB	1
Brown, AM; Dawe-Lane, E; Evans, C; Fowler, M; King, MV; Newton-Mann, E; Shortall, SE	1
de la Fuente-Sandoval, C; Gómez-Cruz, G; Kochunov, P; León-Ortiz, P; Malacara, M; Moncada-Habib, T; Mora-Durán, R; Reyes-Madrigal, F; Rowland, LM	1
Wang, YM; Xiao, YH; Xie, WL	1
Chen, KC; Huang, LC; Lin, SH; Tseng, HH; Yang, YK	1
Haring, L; Kangro, R; Koch, K; Leppik, L; Parksepp, M; Uppin, K; Vasar, E; Zilmer, M	1
Bryll, A; Karcz, P; Kozicz, T; Krzyściak, W; Pilecki, M; Popiela, TJ; Skrzypek, J; Śmierciak, N; Szwajca, M	1
Anton, A; Barker, GJ; Collier, T; Deakin, B; Donocik, J; Drake, R; Egerton, A; Eliasson, E; Emsley, R; Gregory, CJ; Griffiths, K; Howes, OD; Kapur, S; Kassoumeri, L; Knight, L; Lambe, EJB; Lawrie, SM; Lees, J; Lewis, S; Lythgoe, DJ; MacCabe, JH; Matthews, J; McGuire, P; McNamee, L; Murphy, A; Semple, S; Shaw, AD; Singh, KD; Stockton-Powdrell, C; Talbot, PS; Veronese, M; Wagner, E; Walters, JTR; Williams, SR	1
Andersen, GS; Bojesen, KB; Broberg, BV; Edden, RAE; Fagerlund, B; Glenthøj, BY; Jessen, K; Larsson, HBW; Nielsen, MØ; Rostrup, E; Sigvard, A; Tangmose, K; Thomas, MB	1
Aiba, A; Gotoh, Y; Kano, M; Kawaji, K; Kishi, Y; Koebis, M; Nagahama, K; Nakao, K; Sakoori, K; Uesaka, N; Watanabe, T	1
Bhattiprolu, AK; Brzustowicz, LM; Clarke, SG; Crosta, CM; Dudzinski, NR; Firestein, BL; Fu, AY; Hernandez, K; Moore, JC; Paradiso, KG	1
Bossong, MG; Egerton, A; Grace, AA; McGuire, P; Sand, M; Stone, J	1
Ambinder, EB; Barker, PB; Bonekamp, S; Cascella, NG; Coughlin, JM; Edden, RAE; Edwards, JA; Fournier, M; Higgs, CP; Kim, PK; Ma, S; Marsman, A; Pomper, MG; Posporelis, S; Pradhan, S; Sawa, A; Schretlen, DJ; Sedlak, TW; Tsujimura, T; Varvaris, M; Wang, H; Wang, M; Ward, RE; Yang, K	1
Ametamey, SM; Cumming, P; Kim, JH; Marton, J	1
Abani, CP; Beaudreault, CP; Chung, S; Cohen, BM; Coyle, JT; Gonzalez, SZ; Guan, Y; Huang, W; Kim, HY; Lanz, TA; Le, DT; Liu, D; McPhie, DL; Ni, P; Noh, H; Park, GH; Park, JM; Park, JS; Qin, Y; Shao, Z; Xi, HS; Yin, C	1
Fukuda, Y; Heinz, A; Kaminski, J; Katthagen, T; Mascarell-Maricic, L; Schlagenhauf, F	1
Dorner-Ciossek, C; Fischer, S; Gillardon, F; Kizner, V; Naujock, M; Speidel, A	1
Geissah, S; Intson, K; McCullumsmith, RE; Ramsey, AJ	1
Ferrarelli, F; Hetherington, HP; Mayeli, A; Quiñones, GM; Yushmanov, VE	1
Reid, MA	1
Eltokhi, A; Merchan-Perez, A; Santuy, A; Sprengel, R	1
Avila, A; Barker, GJ; Borgan, F; Chang, N; Egerton, A; Ferreira, D; Gillespie, A; Howes, OD; Lally, J; Lythgoe, DJ; MacCabe, JH; McGuire, P; McQueen, G; Sendt, KV; Stone, JM; Vallianatou, K	1
Andrade, YCP; Batista, LA; Del Bel, EA; Fanelli, C; Issy, AC; Liégeois, JF; Minaldi, E; Moreira, FA; Rodrigues, LCM; Ropke, J; Viana, TG	1
Chuchmacz, J; Czarnecka, K; Szymański, P; Wójtowicz, P	1
Benvenutti, R; Gallas-Lopes, M; Herrmann, AP; Marcon, M; Piato, A; Reschke, CR	1
Annibale, L; Bhattacharyya, S; Blest-Hopley, G; Giampietro, V; O'Neill, A; Wilson, R	1
Alves, F; Brzózka, MM; Dullin, C; Fledrich, R; Götze, T; Husseini, H; Linhoff, L; Mießner, H; Nave, KA; Peng, M; Ramos-Gomes, F; Rossner, MJ; Schifferdecker, E; Schwab, MH; Sereda, MW; Soto-Bernardini, MC; Velanac, V; Willig, K; Zhang, M; Zhang, W	1
Aleman, A; Block, W; Bloemen, OJN; Borgan, F; Bustillo, JR; Capizzano, AA; Coughlin, JM; De la Fuente-Sandoval, C; Demjaha, A; Dempster, K; Do, KQ; Du, F; Egerton, A; Falkai, P; Galinska-Skok, B; Gallinat, J; Gasparovic, C; Ginestet, CE; Goto, N; Graff-Guerrero, A; Ho, BC; Howes, OD; Jauhar, S; Jeon, P; Kato, T; Kaufmann, CA; Kegeles, LS; Keshavan, M; Kim, SY; Kunugi, H; Lauriello, J; Liemburg, EJ; McGuire, PK; Mcilwain, ME; Merritt, K; Modinos, G; Mouchlianitis, ED; Nakamura, J; Nenadic, I; Öngür, D; Ota, M; Palaniyappan, L; Pantelis, C; Plitman, E; Posporelis, S; Purdon, SE; Reichenbach, JR; Renshaw, PF; Russell, BR; Sawa, A; Schaefer, M; Shungu, DC; Smesny, S; Stanley, JA; Stone, JM; Szulc, A; Taylor, R; Thakkar, K; Théberge, J; Tibbo, PG; van Amelsvoort, T; Walecki, J; Williamson, PC; Wood, SJ; Xin, L; Yamasue, H	1
Gomes, FV; Grace, AA	1
Gassó, P; Parellada, E	1
Bustillo, J; Howes, OD; McCutcheon, RA; Pillinger, T; Rogdaki, M	1
Chang, CY; Hsieh, YC; Kuo, MC; Lai, WS; Luo, DZ; Pei, JC	1
Allen, P; Diaconescu, AO; Kozhuharova, P	1
Bellomo, A; Borraccino, L; Cuoco, F; De Berardis, D; Delle Monache, S; Fornaro, M; Gianfelice, G; Magnifico, G; Piccininni, C; Ricci, F; Rinaldi, A; Ventriglio, A	1
Akkouh, IA; Andreassen, OA; Budinska, E; Djurovic, S; Grabiec, M; Hribkova, H; Kasparek, T; Sun, YM; Szabo, A	1
Brandão-Teles, C; Cassoli, JS; Guest, PC; Martins-de-Souza, D	1
Barker, GJ; Egerton, A; Keysers, C; Kumari, V; McLaughlin, A; McMullen, K; Modinos, G; Williams, SC	1
Featherstone, R; Lin, R; Mensah-Brown, K; Mihara, T; Siegel, SJ; Sobota, R	1
Aleman, A; Bais, L; Ćurčić-Blake, B; Knegtering, H; Liemburg, E; Pijnenborg, HM; Sibeijn-Kuiper, A	1
Andreou, C; Curic, S; Eichler, I; Eichler, L; Gallinat, J; Hanganu-Opatz, I; Leicht, G; Mulert, C; Polomac, N; Steinmann, S; Thiebes, S; Zöllner, C	1
Hochman, E; Hollander, S; Krivoy, A; Selakovic, M; Sendt, KV; Taler, M; Vilner, Y; Weizman, A	1
Bo-Han He, A; Chen, CC; Huang, ACW	1
Antonucci, LA; Attrotto, M; Bertolino, A; Blasi, G; Di Carlo, P; Fanelli, G; Maddalena, G; Masellis, R; Miccolis, G; Pergola, G; Pignataro, P; Rampino, A; Romano, R; Taurisano, P; Torretta, S; Ursini, G	1
Demro, C; Gold, J; Hong, LE; Kline, E; Reeves, G; Rowland, L; Schiffman, J; Thompson, E; Waltz, J; Wijtenburg, SA	1
Bonvicini, C; Gardella, R; Gennarelli, M; Giacopuzzi, E; Magri, C; Minelli, A; Sacchetti, E; Traversa, M; Valsecchi, P; Vita, A	1
Demjaha, A	1
Nakajima, SL; Tsugawa, S	1
Snyder, GL; Vanover, KE	2
Cohen, BM; Coyle, JT; Du, F; Jensen, JE; Kaufman, MJ; Kim, SY; Öngür, D	1
Chiappelli, J; Gaston, F; Gaudiot, C; Hong, LE; Kochunov, P; Kodi, P; Quiton, R; Rowland, LM; Shi, Q; Wijtenburg, SA; Wisner, K	1
Avissar, M; Javitt, D	1
Carlson, M; Carter, CS; Choo, TH; Corlett, PR; Girgis, RR; Grinband, J; Javitt, DC; Kantrowitz, JT; Kegeles, LS; Krystal, JH; Lesh, TA; Lieberman, JA; Maddock, RJ; Mason, G; Potter, WZ; Qiu, M; Ragland, JD; Robinson, J; Rothman, DL; Tanase, C; Wall, MM	1
Kraguljac, NV; Lahti, AC	1
Bergman, J; Carlezon, WA; Coyle, JT; Desai, RI; Donahue, RJ; Doyle, MR; Landino, SM; Presti, KT; Puhl, MD; Takagi, S	1
Bouchet, D; Dalmau, J; Dupuis, JP; Gréa, H; Groc, L; Hamdani, N; Honnorat, J; Jézéquel, J; Johansson, EM; Kellermayer, B; Le Guen, E; Leboyer, M; Lepleux, M; Mathias, E; Rabu, C; Ramsey, AJ; Rogemond, V; Spatola, M; Tamouza, R; Yolken, RH	1
Bhatia, T; Deshpande, SN; Goyal, S; Khushu, S; Kumar, P; Singh, S	1
Fei, J; Li, J; Shi, J; Wan, Y; Wan, Z; Wang, Y; Wang, Z; Yang, H; Zhang, M; Zhou, Y	1
Bazmi, HH; Chen, K; Dienel, SJ; Hoftman, GD; Lewis, DA; Zhang, Y	1
Jelen, LA; King, S; Mullins, PG; Stone, JM	1
Denney, TS; Gawne, TJ; Lahti, AC; Reid, MA; Salibi, N; White, DM	1
Berquist, MD; Fantegrossi, WE; Wilson, CD	1
Alshehri, Y; Caravaggio, F; Chakravarty, MM; Chavez, S; Chung, JK; De Luca, V; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Nakajima, S; Plitman, E; Remington, G	1
Javitt, DC	7
Arnsten, AFT; Datta, D	1
Barker, PB; Cascella, NG; Coughlin, JM; Edden, RAE; Edwards, JA; Ford, CN; Higgs, C; Kim, PK; Lloyd, AM; Marsman, A; Posporelis, S; Pradhan, S; Sawa, A; Schretlen, DJ; Tanaka, T; Varvaris, M; Wang, H; Ward, R	1
Law, AJ; Paterson, C	1
Duarte, JMN; Xin, L	1
Adham, N; Gyertyán, I; Ichinose, F; Kehr, J; Kiss, B; Yoshitake, S; Yoshitake, T	1
Barry, G; Bitar, M; Brennand, KJ; Guennewig, B; Hanks, J; Hurd, YL; Kaczorowski, DC; O'Brien, EA; Obiorah, I; Roussos, P	1
Chiappelli, J; Hong, LE; Jones, A; Kochunov, P; Notarangelo, FM; Pocivavsek, A; Rowland, LM; Schwarcz, R; Thomas, MAR; Wijtenburg, SA; Wisner, K	1
Chen, H; Cho, KIK; Gaston, FE; Kim, M; Kwon, JS; Lee, J; Lee, TY; Rowland, LM; Song, IC; Wijtenburg, SA; Yoon, YB	1
Baandrup, L; Barker, GJ; Broberg, BV; Dazzan, P; Düring, SW; Egerton, A; Glenthøj, B; Kahn, RS; Lythgoe, DJ; McGuire, P; Merritt, K; Perez-Iglesias, R; Rostrup, E; Sendt, KV; Sommer, IE; Stone, JM; Van Haren, N	1
Chen, H; Chiappelli, JJ; Hong, LE; Kochunov, P; Rowland, LM; Shukla, DK; Wijtenburg, SA	1
Brookes, MJ; Christodoulou, NG; Fernandes, CC; Fiesal, J; Hall, EL; Katshu, MZ; Kumar, J; Liddle, EB; Liddle, PF; Morris, PG; Palaniyappan, L; Qureshi, A; Robson, SE; Simmonite, M; Skelton, M	1
Bertron, JL; Lindsley, CW; Seto, M	1
Stahl, SM	2
Cubała, WJ; Wiglusz, MS; Włodarczyk, A	1
Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E	1
Barker, GJ; Collier, T; Egerton, A; Lally, J; Lythgoe, DJ; MacCabe, JH; McGuire, P; McQueen, G; Stone, JM; Zelaya, F	1
Pilc, A; Wierońska, JM	1
Harrison, PJ	2
Gonzales, SS; Kraguljac, NV; Lahti, AC; Morgan, CJ; Sivaraman, S; White, DM	1
Araki, T; Fujioka, M; Ichikawa, E; Kanehara, A; Kasai, K; Kirihara, K; Koike, S; Koshiyama, D; Matsuoka, J; Morita, K; Nagai, T; Ohta, K; Satomura, Y; Sawada, K; Suga, M; Tada, M; Tani, M; Tsuchiya, M	1
Anhøj, SJ; Broberg, BV; Brouwer, R; Fagerlund, B; Glenthøj, BY; Hilker, R; Jensen, MH; Legind, CS; Mandl, RCW; McGuire, P; Pol, HH; Rostrup, E	1
Barbon, A; Bonini, D; Bresciani, R; Elhussiny, MEA; Gangemi, F; Gennarelli, M; Giacopuzzi, E; La Via, L; Magri, C; Orizio, F; Ravasio, V; Valsecchi, P; Vita, A	1
Caravaggio, F; Chavez, S; De Luca, V; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Mar, W; Mimura, M; Nakajima, S; Plitman, E; Remington, G; Shah, P	1
Bhakoo, KK; Duytschaever, H; Garnell, JF; Grandjean, J; Sekar, S; Seramani, S; Su, H; Ver Donck, L; Willems, R	1
Dwyer, GE; Grüner, R; Hugdahl, K; Specht, K	1
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Geyer, MA; Powell, SB; Zhou, X	1
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Tan, HY	1
Blendy, JA; Brodkin, ES; Christian, EP; Dow, HC; Ehrlichman, RS; Gur, RC; Gur, TL; Halene, TB; Jonak, GJ; Liang, Y; Schneider, F; Siegel, SJ	1
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Fendri, C; Gaha, L; Kerkeni, A; Mechri, A; Othman, LB; Raffa, M	1
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Aboitiz, F; Bustamante, ML; Gaspar, PA; Silva, H	1
Stone, JM	1
Kähkönen, S; Korostenskaja, M	1
Albuquerque, EX; Bruno, JP; Pellicciari, R; Pereira, EF; Schwarcz, R; Wu, HQ	1
Sawa, A	1
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Kristiansen, LV; Pakkenberg, B; Scheel-Krüger, J	1
Gaisler-Salomon, I; Rayport, S; Schobel, SA; Small, SA	1
Aoki, T; Kanuma, K; Shimazaki, Y	1
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Kirby, BP; Moran, PM; O'Tuathaigh, CM; Waddington, JL	1
Boules, M; Li, Z; Peris, J; Richelson, E; Williams, K	1
Davis, GW; Dickman, DK	1
Gordon, JA	1
Bambini-Junior, V; Bobermin, LD; Gottfried, C; Quincozes-Santos, A; Riesgo, R; Tonial, RP	1
Cherlyn, SY; Liu, JJ; Ong, WY; Sim, K; Tsai, GC; Woon, PS	1
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Eastwood, SL; Harrison, PJ	2
O'Tuathaigh, CM; Waddington, JL	1
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Miller, GW; Qi, Z; Voit, EO	1
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Arai, H; Ohnuma, T	1
Choi, YK; Tarazi, FI	1
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Apfeldorf, W; Bustillo, JR; Caprihan, A; Chen, H; Gasparovic, C; Lauriello, J; Mullins, P; Posse, S; Qualls, C	1
Calcagno, E; Carli, M; Invernizzi, RW; Mainini, E; Mainolfi, P	1
Adams-Marriott, AL; Doucette, TA; Gallant, IC; Robbins, MA; Ryan, CL; Smith, MT	1
Fejgin, K; Klamer, D; Pålsson, E; Svensson, L	1
Yan, Z; Yuen, EY; Zhong, P	1
Papaleo, F; Weinberger, DR	1
Chaki, S; Okuyama, S; Yoshida, S	1
Byne, W; Haroutunian, V; Katsel, P; Roussos, P; Siever, L; Tan, W	1
Cadagan, R; García-Sastre, A; González-Maeso, J; Holloway, T; Kurita, M; López, J; Martínez-Sobrido, L; Moreno, JL	1
Labrie, V; Roder, JC; Wong, AH	1
Nabeshima, T	1
Chaki, S; Hikichi, H	1
Abekawa, T; Ito, K; Koyama, T; Nakato, Y	1
Hoftman, GD; Lewis, DA	1
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Meyer-Lindenberg, A; Tost, H	1
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Ahlbrand, R; Bronson, SL; Gudelsky, G; Kern, JR; Richtand, NM; Roenker, NL; Waterman, H	1
Bernstein, HG; Bogerts, B; Gos, T; Myint, AM; Sarnyai, Z; Steiner, J; Walter, M	1
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Lahti, AC; Reid, MA	1
Falkai, P; Gruber, O; Schmitt, A; Yeganeh-Doost, P	1
Motomura, E; Nakagawa, M; Okada, M; Tanahashi, S; Yamamura, S	1
Liu, Y; Pu, W; Tang, Y; Zhang, X; Zhao, J	1
Cuenod, M; das Neves Duarte, JM; Do, KQ; Gholam-Razaee, MM; Gruetter, R; Kulak, A	1
Javitt, D; Moghaddam, B	1
Adell, A; Jiménez-Sánchez, L; López-Gil, X; Romón, T	1
Alexander, KS; Bruno, JP; Schwarcz, R; Wu, HQ	1
Grayson, DR	1
Dome, P; Faludi, G; Lazary, J	1
Abi-Dargham, A; Gil, R; Girgis, R; Kegeles, LS; Lisanby, SH; Mao, X; Ojeil, N; Shungu, DC; Slifstein, M; Stanford, AD; Xu, X	1
Ibi, D; Nabeshima, T; Nagai, T; Yamada, K	1
Egerton, A; Stone, JM	1
Bustamante, ML; Gaspar, PA; Martinez, A; Rojo, LE	1
Funk, A; Hammond, J; McCullumsmith, RE; Meador-Woodruff, JH	1
Javitt, DC; Kantrowitz, J	1
Haroutunian, V; McCullumsmith, RE; Meador-Woodruff, JH; Shan, D	1
Buonocore, MH; Maddock, RJ	1
Bencherif, M; Kucinski, AJ; Lippiello, PM; Stachowiak, MK	1
Chen, YJ; Mei, L; Sathyamurthy, A; Xiong, WC; Yin, DM	1
Gonzalez-Burgos, G; Lewis, DA	2
de Bartolomeis, A; Iasevoli, F; Magara, S; Sarappa, C	1
Arancio, O; Chuhma, N; Gaisler-Salomon, I; Golumbic, YN; Mihali, A; Rayport, S; Sibille, E; Wang, Y; Zhang, H	1
Hattori, K; Hori, H; Ishikawa, M; Kunugi, H; Nakata, Y; Ota, M; Sasayama, D; Sato, N; Teraishi, T	1
Bramon, E; Chaddock, CA; Collier, DA; Ehlert, N; Fu, CH; Georgiades, A; Kalidindi, S; Kane, F; Kravariti, E; McDonald, C; McGuire, P; Mechelli, A; Murray, R; Pauli, A; Picchioni, M; Prata, DP; Toulopoulou, T; Walshe, M	1
Ghose, S; Sacco, C; Southcott, S; Tamminga, CA; Wagner, AD	1
Bzdega, T; Moffett, JR; Neale, JH; Olszewski, RT; Zuo, D	1
Ahlbrand, R; Gudelsky, GA; Horn, PS; Richtand, NM; Roenker, NL	1
Adachi, Y; Aleksic, B; Banno, M; Hashimoto, R; Iidaka, T; Ikeda, M; Inada, T; Iwata, N; Kawano, N; Kikuchi, T; Kohmura, K; Koide, T; Kushima, I; Nakamura, Y; Ohi, K; Okada, T; Ozaki, N; Suzuki, M; Takeda, M; Ujike, H; Yamashita, S; Yasuda, Y	1
Grant, JS; Keltner, NL; Moore, RL; Steele, D; Swan, NA	1
Bechi, M; Benedetti, F; Bosia, M; Bramanti, P; Cavallaro, R; Cocchi, F; Lorenzi, C; Pirovano, A; Smeraldi, E; Spangaro, M; Zanoletti, A	1
Barker, GJ; Brugger, S; Egerton, A; Lythgoe, DJ; McGuire, PK; Raffin, M; Stone, JM	1
den Hollander, J; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM	1
Avsar, KB; Bolding, MS; den Hollander, JA; Hutcheson, NL; Knowlton, RC; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM	1
Gururajan, A; Klug, M; Manning, EE; van den Buuse, M	1
Krystal, JH; Moghaddam, B	1
Buckley, PF; Pillai, A	1
Coyle, JT	1
Diaz, J; Leriche, L; Louvel, J; Pumain, R; Sokoloff, P	1
Balu, D; Basu, A; Benneyworth, M; Coyle, JT; Konopaske, G	1
Amess, B; Bahn, S; Guest, PC; Harris, LW; Ma, D; Oheim, C; Ozanne, SE; Pietsch, S; Stelzhammer, V; Urday, S	1
Barker, PB; Edden, RA; Holcomb, HH; Kontson, K; Rowland, LM; West, J; Wijtenburg, SA; Zhu, H	1
Drummond, JB; Haroutunian, V; Meador-Woodruff, JH; Simmons, M	1
Abi-Dargham, A; Kuepper, R; Skinbjerg, M	1
Ibi, D; Mouri, A; Nagai, T; Yamada, K	1
Abrusán, G	1
Buonaguro, EF; de Bartolomeis, A; Iasevoli, F	1
Conn, PJ; Jones, CK; Noetzel, MJ	1
Boot, E; van Amelsvoort, TA	1
Liddle, PF; Palaniyappan, L; White, TP	1
Cohn, T; Hahn, MK; Remington, G; Teo, C	1
Drummond, JB; Haroutunian, V; Lucas, EK; McCullumsmith, RE; Meador-Woodruff, JH; Shan, D	1
Heckers, S; Konradi, C	1
Magistretti, P; Pralong, E; Stoop, R	1
Kalkman, HO	1
Al-Semaan, Y; Bartha, R; Densmore, M; Drost, DJ; Malla, A; Menon, RS; Neufeld, RW; Pavlosky, W; Rogers, J; Schaefer, B; Takhar, J; Théberge, J; Williamson, PC	1
Bellack, AS; Billingslea, EN; Deutsch, SI; Mastropaolo, J; Rosse, RB	1
Braff, DL; Kelsoe, JR; Schuckit, MA; Wilhelmsen, KC	1
Bedogni, F; Fossati, C; Fumagalli, F; Gennarelli, M; Molteni, R; Racagni, G; Riva, MA; Roceri, M; Santero, R	1
Holden, C	1
Anderson, JJ; Baccei, CS; Bristow, LJ; Campbell, UC; Correa, LD; Lorrain, DS; Pinkerton, AB; Rodriguez, DE; Rowe, B; Schaffhauser, H; Varney, MA; Vernier, JM	1
Caron, MG; Gainetdinov, RR; Gerber, DJ; Leiter, LM; Miyakawa, T; Sotnikova, TD; Tonegawa, S; Zeng, H	1
Herman, MM; Hyde, TM; Kleinman, JE; Lipska, BK; Weickert, CS; Weinberger, DR	1
Akahane, A; Nanko, S	1
Belger, A; D'Souza, DC; Hoffman, R; Krystal, JH; Mathalon, D; Perry, E	1
FOSS, OP	1
COCCONCELLI, C; MASTROBUONO, M; PECORARI, T	1
Fukuda, R; Fukui, T; Iwanami, A; Kasai, K; Kato, N; Kato, T; Yamasue, H	1
Collier, DA; Li, T	1
Takaki, M; Ujike, H	1
Al-Semaan, Y; Densmore, M; Drost, DJ; Menon, RS; Neufeld, RW; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, PC	1
Moghaddam, B	1
Coyle, JT; Javitt, DC	1
Charara, A; Floresco, SB; Grace, AA; Rosenkranz, JA; West, AR	1
Brody, SA; Conquet, F; Geyer, MA	1
Bonta, IL	1
Koch, M; Schwabe, K	1
Itokawa, M; Yoshikawa, T	1
ASTRUP, P; MUNKVAD, I	1
Carlsson, A; Carlsson, ML; Nilsson, M	1
Gulcher, JR; Stefansson, H; Stefansson, K; Steinthorsdottir, V; Thorgeirsson, TE	1
Coyle, JT; Tsai, G	2
O'Donovan, MC; Owen, MJ; Williams, NM	1
Allen, P; Hanstock, C; Tibbo, P; Valiakalayil, A	1
Diaz, J; Leriche, L; Sokoloff, P	1
Castner, SA; Goldman-Rakic, PS; Williams, GV	1
Engberg, G; Erhardt, S; Schwieler, L	1
Carlsson, A; Carlsson, ML; Gullme, M; Markinhuhta, KR; Nilsson, M; Pettersson, F; Sonesson, C	1
Trudeau, LE	1
Baccei, CS; Bristow, LJ; Campbell, UC; Daggett, LP; Lorrain, DS; Pinkerton, AB; Rodriguez, DE; Rowe, BA; Schaffhauser, H; Vernier, JM	1
Holcomb, HH; Tamminga, CA	1
Hashimoto, R; Ishimoto, T; Iwata, N; Kamijima, K; Kunugi, H; Numakawa, T; Okada, T; Ozaki, N; Straub, RE; Suzuki, T; Taguchi, T; Tatsumi, M; Weinberger, DR; Yagasaki, Y	1
Domino, EF; Mirzoyan, D; Tsukada, H	1
RAVN, J	1
Clinton, SM; Meador-Woodruff, JH	1
Jahanshahi, M; Limousin-Dowsey, P; Silberstein, P; Tisch, S	1
Jann, MW	1
Abi-Dargham, A; Laruelle, M	1
Garcia, R; Hunt, MJ; Kessal, K	1
Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pfleiderer, B; Siegmund, A; Spitzberg, K; Suslow, T	1
Engberg, G; Hashimoto, K; Iyo, M; Lindström, LH; Nordin, C; Shimizu, E	1
Rands, GS	1
Aschauer, HN; Schosser, A	1
Boulay, LJ; Chouinard, S; Stip, E	1
Conti, F; Matute, C; Melone, M; Torres-Ramos, M; Vallejo-Illarramendi, A	1
Hinoi, E; Takarada, T; Tsuchihashi, Y; Yoneda, Y	1
Beneyto, M; Dean, B; Meador-Woodruff, JH; Scarr, E	1
Arai, H; Ohnuma, T; Suzuki, T	1
Grace, AA; Pogue-Geile, MF; Thompson, JL	1
Bagorda, F; Lehmann, K; Teuchert-Noodt, G	1
Goff, DC; Large, CH; Webster, EL	1
Dehoff, MH; Kalivas, PW; Kleschen, MJ; Lominac, KD; Oleson, EB; Schwartz, MK; Schwarz, MK; Seeberg, PH; Seeburg, PH; Szumlinski, KK; Worley, PF	1
Bubl, E; Büchert, M; Ebert, D; Hennig, J; Olbrich, HM; Rüsch, N; Thiel, T; Valerius, G; van Elst, LT	1
Atzori, M; Flores-Hernandez, J; Kanold, PO; Paz, RD; Pineda, JC	1
Tsai, SJ	1
Abi-Dargham, A; Frankle, WG; Kegeles, LS; Laruelle, M; Narendran, R	1
Balcar, VJ; Nanitsos, EK; Nguyen, KT; St'astný, F	1
Heresco-Levy, U	1
Tanaka, S	1
Toru, M	2
Brenner, E; Carlsson, ML; Eyjolfsson, EM; Kondziella, D; Markinhuhta, KR; Sonnewald, U	1
Baldeweg, T; Friston, KJ; Stephan, KE	1
Chopra, V; Flibotte, S; Holt, RA; Honer, WG; Melnyk, BL; Wilson, GM	1
Gottesmann, C	1
Giménez-Amaya, JM; Haroutunian, V; Huerta, I; McCullumsmith, RE; Meador-Woodruff, JH	1
Winterer, G	1
Abbott, C; Bustillo, J	1
Keramat Ali, SM; Morshed, NM; Nahar, JS; Shams, M; Sobhan, MA	1
Beauchamp, AS; Lema Tomé, CM; Leung, PW; Nottingham, CU; Smith, CM; Turner, CP	1
Bortolato, M; Casti, A; Fà, M; Fais, N; Frau, R; Gessa, G; Manunta, M; Mereu, G; Orrù, M	1
Bhattacharya, P; Harris, K; Lin, A; Ross, B; Tran, T; Wong, W	1
Del-Favero, J; Van Broeckhoven, C; Van Den Bogaert, A	1
Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pedersen, A; Pfleiderer, B; Rothermundt, M; Siegmund, A; Spitzberg, K; Suslow, T	1
Jensen, JE; Rowland, LM; Théberge, J	1
Beneyto, M; Meador-Woodruff, JH	1
Montes, S; Pérez-Neri, I; Ramírez-Bermúdez, J; Ríos, C	1
Andreasen, NC; Bustillo, J; Conley, R; Daoud, SZ; Paz, RD; Perrone-Bizzozero, NI; Roberts, R	1
Lewis, DA; Moghaddam, B	1
Muller, N; Schwarz, M	1
Brenner, E; Eyjolfsson, EM; Kondziella, D; Sonnewald, U	1
Abekawa, T; Ito, K; Koyama, T	1
Beneyto, M; Dean, B; Kristiansen, LV; McCullumsmith, RE; Meador-Woodruff, JH; Scarr, E	1
Agam, G; Amar, S; Bendikov, I; De Miranda, J; Nadri, C; Panizzutti, R; Wolosker, H	1
Mouri, A; Murai, R; Nabeshima, T; Noda, Y	1
Morrison, PD; Pilowsky, LS	1
Lewis, BL; Lipska, BK; O'Donnell, P; Tseng, KY	1
Fellin, T; Halassa, MM; Haydon, PG	1
Acosta, GB; Scolari, MJ	1
Boks, MP; de Koning, TJ; Kahn, RS; Rietkerk, T; Sommer, IE; van de Beek, MH	1
Balaraman, Y; Edenberg, HJ; Faraone, SV; Geyer, MA; Jerome, RE; Kuczenski, R; Le-Niculescu, H; Niculescu, AB; Nurnberger, JI; Patel, S; Sidhu, K; Tan, J; Tsuang, MT	1
Bar, G; Ebstein, RP; Ermilov, M; Heresco-Levy, U; Javitt, DC; Levin, R	1
Chessel, A; Garcia, R; Krebs, MO; Le Pen, G; Léna, I	1
Bahn, S; Huffaker, SJ; Mimmack, ML; Ryan, M; Tkachev, D	1
Ballmaier, M; Bortolato, M; Gessa, G; Heinz, A; Rizzetti, C; Spano, P; Zoli, M	1
Andrieux, A; Brenner, E; Nehlig, A; Schweitzer, A; Sonnewald, U	1
Ambesi-Impiombato, A; de Bartolomeis, A; Iasevoli, F; Muscettola, G; Polese, D	1
Adell, A; Amargós-Bosch, M; Artigas, F; Babot, Z; López-Gil, X; Suñol, C	1
Harte, MK; Reynolds, GP	1
Albalushi, T; Arinami, T; Horiuchi, Y; Inada, T; Ishiguro, H; Iwata, N; Koga, M; Muratake, T; Ozaki, N; Someya, T; Ujike, H	1
Adell, A; Amargós-Bosch, M; Artigas, F	1
Boksha, IS; Burbaeva, GSh; Mukaetova-Ladinska, E; Savushkina, OK; Starodubtseva, LI; Tereshkina, EB; Turishcheva, MS	1
Archer, T; Beninger, RJ; Kostrzewa, RM; Palomo, T	1
Cilia, J; Hatcher, P; Jones, DN; Reavill, C	1
Enomoto, T; Nabeshima, T; Noda, Y	1
Abe, S; Arai, H; Baba, H; Higashi, M; Ichikawa, A; Ihara, H; Maeshima, H; Nakano, Y; Nozawa, E; Ohkubo, T; Ohnuma, T; Sakai, Y; Shibata, N; Suzuki, T; Utsumi, Y	1
Celikel, T; Daws, LC; Feyder, M; Hefner, K; Holmes, A; Horton, RE; Karlsson, RM; Owens, WA; Sprengel, R; Wiedholz, LM	1
Pilowsky, LS; Stone, JM	1
Chang, L; Davis, K; Ernst, T; Friedman, J; Tsopelas, ND; Zhong, K	1
Baker, DA; Haroutunian, V; Kristiansen, LV; Madayag, A; Meador-Woodruff, JH; Raju, I	1
Ary, AW; Lominac, KD; Szumlinski, KK	1
Buchert, M; Ebert, D; Hennig, J; Olbrich, HM; Rüsch, N; Thiel, T; Valerius, G; Van Elst, LT	1
Hashimoto, K; Koizumi, S; Kudo, Y; Wada, K	1
Aoyama, N; Densmore, M; Drost, DJ; Malla, AK; Manchanda, R; Menon, RS; Neufeld, RW; Northcott, S; Pavlosky, W; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, KE; Williamson, PC	1
Adams, AL; Doucette, TA; Ryan, CL	1
Christensen, BK; Daskalakis, ZJ; Fitzgerald, PB	1
Gallinat, J; Lang, UE; Muller, DJ; Puls, I; Strutz-Seebohm, N	1
ARNOLD, DG; KITZINGER, H	1
Tizabi, Y	1
Hanstock, CC; Purdon, SE; Seres, P; Tibbo, P; Valiakalayil, A	1
Abekawa, T; Ito, K; Koyama, T; Nakagawa, S; Nakato, Y	1
Chen, SH; Chong, SA; Chua, HC; Sim, K; Watis, L	1
Butts, BD; Houde, C; Mehmet, H	1
Brand, U; Kim, JS; Kornhuber, HH; Menge, HG	1
Perry, TL	1
Shen, QJ	1
Simpson, JC	1
Claus, D; Kim, JS; Kornhuber, HH; Schmid-Burgk, W	1
Claus, D; Kim, JS; Kornhuber, HH	1
Kornhuber, HH	1
Wang, RY; White, FJ	1
Kim, JS; Kornhuber, HH; Kornhuber, J; Kornhuber, ME	1
Henn, FA	1
Bustos, G; Jerez, S; Labarca, R; Ogalde, C; Renterías, P; Ruiz, A; Silva, H	1
Deakin, JF	1
Ishimaru, M; Kurumaji, A; Toru, M	1
Stefanis, CN	1
Lajtha, A; Palkovits, M; Saederup, E; Squires, RF	1
Kornhuber, J; Weller, M	1
Williamson, PC	1
Koffel, B; Lahti, AC; LaPorte, D; Tamminga, CA	1
Maes, M; Smith, RS	1
Halberstadt, AL	1
Acosta, GB; Wikinski, SI	1
Banerjee, SP; Lidsky, TI; Yablonsky-Alter, E; Zuck, LG	1
Choe, BY; Lee, C; Lee, CW; Paik, IH; Shinn, KS; Suh, TS	1
Gao, XM; Holcomb, HH; Lahti, AC; Tamminga, CA	1
Carr, TJ; Drost, DJ; Malla, A; Rylett, RJ; Stanley, JA; Thompson, RT; Williamson, PC	1
Tollefson, GD	1
Frusciante, M; Javitt, DC	1
Das, I; de Belleroche, J; Garey, LJ; Hirsch, SR	1
Carlsson, A; Carlsson, ML; Hansson, LO; Waters, N	2
Deakin, FW; Hellewell, JS; Simpson, MD; Slater, P	1
Weinberger, DR	1
Aparicio-Legarza, MI; Cutts, AJ; Davis, B; Reynolds, GP	1
Goldman-Rakic, PS; Selemon, LD	1
Aston-Jones, G; Gerfen, CR; Grace, AA	1
Bartha, R; Canaran, G; Carr, TJ; Cortese, L; Drost, DJ; Malla, A; Neufeld, RW; Rylett, RJ; Williamson, PC	1
Egan, MF; Weinberger, DR	1
Goff, DC; Wine, L	1
Fedtsova, N; Jeste, DV; Turner, EE	1
Tamminga, CA	1
Amico, ET; Evins, AE; Goff, DC; Shih, V	1
Bardgett, ME; Csernansky, JG	1
Geyer, MA; Swerdlow, NR	1
Benes, FM; Deakin, JF; Longson, D	1
Adams, BW; Moghaddam, B	1
Wickelgren, I	1
Chen, S; Coyle, JT; Grier, A; Kelley, ME; Tsai, G; van Kammen, DP	1
Semba, J	1
Dalack, GW; Healy, DJ; Meador-Woodruff, JH	1
Bardgett, M; Csernansky, JG; Faull, KF; Faustman, WO; Pfefferbaum, A	1
Farber, NB; Newcomer, JW; Olney, JW	1
Herrera-Marschitz, M; Hökfelt, T; Koistinaho, J; Rodríguez-Puertas, R	1
Breier, A	1
Tamminga, C	1
Glenthøj, BY; Hemmingsen, R	1
Innis, RB; Soares, JC	1
Carlsson, A; Carlsson, ML; Waters, N	2
Greene, RW; Grunze, H; Hirayasu, Y; McCarley, RW; Nestor, PG; Niznikiewicz, MA; O'Donnell, BF; Salisbury, DF; Shenton, ME	1
Deicken, RF; Johnson, C; Pegues, M	1
Aghajanian, GK; Marek, GJ	1
Sharp, FR; Tolliver, BK; Tomitaka, M; Tomitaka, S	1
Sabel, BA; Schroeder, H; Schroeder, U; Schwegler, H	1
Anjilvel, S; Chan, S; Ellis, SP; Gorman, JM; Kaufmann, CA; Kegeles, LS; Laruelle, M; Malaspina, D; Mann, JJ; Shungu, DC; Xanthopoulos, E	1
Kawaguchi, N; Nishikawa, T; Tsuchida, H; Umino, A; Yamamoto, N	1
Benes, FM; Berretta, S	1
Boulenguez, P; Chauveau, J; Gray, JA; Joseph, MH; Mitchell, SN; Peters, SL	1
Arai, H; Emson, PC; Faull, RL; Kato, H; McKenna, PJ; Ohnuma, T	1
Al-Amin, HA; Lipska, BK; Weinberger, DR	1
Arinami, T; Sakurai, K; Toru, M; Yamakawa-Kobayashi, K	1
Carlsson, A; Carlsson, ML; Holm-Waters, S; Nilsson, M; Tedroff, J; Waters, N	1
Davis, KL; Haroutunian, V; Meador-Woodruff, JH	1
Gaudet, I; Halim, ND; Hanlon, FM; Henning, L; Kim, YK; Swerdlow, NR	1
Belmonte-de-Abreu, P; Brunstein, MG; Lara, DR; Souza, DO	1
Bleich, K; Bleich, S; Kornhuber, J; Maler, JM; Wiltfang, J	1
Davis, KL; Haroutunian, V; Meador-Woodruff, JH; Smith, RE	1
Deakin, JF; Law, AJ	1
Blennow, K; Engberg, G; Erhardt, S; Lindström, LH; Nordin, C; Skogh, E	1
De Luca, L; Fabrazzo, M; Maj, M; Monteleone, P; Tortorella, A; Viggiano, A	1
Kilts, CD	1
Evins, AE; Goff, DC; Hennen, J; Lyoo, IK; Renshaw, PF; Tsai, G; Wald, LL; Yurgelun-Todd, DA	1
Shim, SS	1
Gispen-De Wied, CC; Kahn, RS; Scheepers, FE; Westenberg, HG	1
Davis, KL; Gluck, MR; Haroutunian, V; Thomas, RG	1
Danielczyk, W; Kornhuber, J; Lange, KW; Riederer, P	1
Deakin, JF; Royston, MC; Simpson, MD; Slater, P	2
Baruah, S; Davidson, AT; Hegwood, TS; Sherman, AD; Waziri, R	1
Grace, AA	1
Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R	1
Jellinger, K; Kornhuber, J; Lange, KW; Riederer, P	1
Carlsson, A; Carlsson, M	2
Javitt, DC; Zukin, SR	1
Bracha, HS; Kleinman, JE	1
Cross, AJ; Deakin, JF; Gilchrist, AC; Reynolds, GP; Royston, MC; Simpson, MD; Skan, WJ; Slater, P	1
Voigt, MM; Wang, RY; White, FJ	1
Kaufmann, CA; Korpi, ER; Marnela, KM; Weinberger, DR	1
Javitt, DC; Jotkowitz, A; Sircar, R; Zukin, SR	1
Czudek, C; Kerwin, RW; Meldrum, BS; Patel, S; Reynolds, GP	1

Reviews

252 review(s) available for glutamic acid and Schizophrenia

Article	Year
Cystine/Glutamate Antiporter in Schizophrenia: From Molecular Mechanism to Novel Biomarker and Treatment. International journal of molecular sciences, 2021, Sep-08, Volume: 22, Issue:18 Topics: Animals; Antiporters; Biological Transport; Biomarkers; Cystine; Disease Management; Disease Susceptibility; Glutamic Acid; Humans; Neurons; Neurotransmitter Agents; Oxidative Stress; Precision Medicine; Schizophrenia; Synaptic Transmission	2021
Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of Molecular psychiatry, 2022, Volume: 27, Issue:1 Topics: gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2022
Frontal neural metabolite changes in schizophrenia and their association with cognitive control: A systematic review. Neuroscience and biobehavioral reviews, 2022, Volume: 132 Topics: Brain; Cognition; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Schizophrenia	2022
Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies. International journal of molecular sciences, 2021, Dec-07, Volume: 22, Issue:24 Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Receptors, G-Protein-Coupled; Schizophrenia; Small Molecule Libraries	2021
Metabotropic Glutamate Receptors As Emerging Targets for the Treatment of Schizophrenia. Molecular pharmacology, 2022, Volume: 101, Issue:5 Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Glutamic Acid; Humans; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2022
Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia. Molecular psychiatry, 2022, Volume: 27, Issue:9 Topics: Corpus Striatum; Dopamine; Glutamic Acid; Humans; Schizophrenia; Synaptic Transmission	2022
The mGlu Pharmacology, biochemistry, and behavior, 2022, Volume: 218 Topics: Animals; Antipsychotic Agents; Glutamic Acid; Ligands; Male; Mice; Receptors, Metabotropic Glutamate; Schizophrenia	2022
Beyond NMDA Receptors: Homeostasis at the Glutamate Tripartite Synapse and Its Contributions to Cognitive Dysfunction in Schizophrenia. International journal of molecular sciences, 2022, Aug-03, Volume: 23, Issue:15 Topics: Cognitive Dysfunction; Glutamic Acid; Homeostasis; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses	2022
Linking Inflammation, Aberrant Glutamate-Dopamine Interaction, and Post-synaptic Changes: Translational Relevance for Schizophrenia and Antipsychotic Treatment: a Systematic Review. Molecular neurobiology, 2022, Volume: 59, Issue:10 Topics: Antipsychotic Agents; Dopamine; Glutamic Acid; Humans; Inflammation; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2022
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:8 Topics: Acute Kidney Injury; Adult; Aged; Aortic Dissection; Child; Depression; Glutamate Dehydrogenase; Glutamic Acid; Glutathione; Glutathione Reductase; Glutathione Transferase; Humans; Male; Postoperative Complications; Retrospective Studies; Risk Factors; Schizophrenia; Young Adult	2022
The role of excitatory amino acid transporter 2 (EAAT2) in epilepsy and other neurological disorders. Metabolic brain disease, 2023, Volume: 38, Issue:1 Topics: Animals; Biological Transport; Epilepsy; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Mammals; Schizophrenia	2023
Systematic analysis to identify novel disease indications and plausible potential chemical leads of glutamate ionotropic receptor NMDA type subunit 1, GRIN1. Journal of molecular recognition : JMR, 2023, Volume: 36, Issue:1 Topics: Computer Simulation; Glutamic Acid; Humans; Nerve Tissue Proteins; Rare Diseases; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2023
Glutamatergic dysfunction in Schizophrenia. Translational psychiatry, 2022, 12-03, Volume: 12, Issue:1 Topics: Dopamine; Glutamic Acid; Humans; Ketamine; N-Methylaspartate; Schizophrenia	2022
The Role of D-Serine and D-Aspartate in the Pathogenesis and Therapy of Treatment-Resistant Schizophrenia. Nutrients, 2022, Dec-02, Volume: 14, Issue:23 Topics: Aspartic Acid; D-Aspartic Acid; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenia, Treatment-Resistant; Serine	2022
Neurofunctional correlates of glutamate and GABA imbalance in psychosis: A systematic review. Neuroscience and biobehavioral reviews, 2023, Volume: 144 Topics: gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Psychotic Disorders; Schizophrenia	2023
Understanding translational research in schizophrenia: A novel insight into animal models. Molecular biology reports, 2023, Volume: 50, Issue:4 Topics: Animals; Disease Models, Animal; Dopamine; Glutamic Acid; Schizophrenia; Serotonin; Translational Research, Biomedical	2023
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis. Molecular psychiatry, 2023, Volume: 28, Issue:5 Topics: Brain; Glutamic Acid; Glutamine; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2023
Epigenetic regulation of metabotropic glutamate 2/3 receptors: Potential role for ultra-resistant schizophrenia? Pharmacology, biochemistry, and behavior, 2023, Volume: 229 Topics: Animals; DNA Methylation; Epigenesis, Genetic; Female; Frontal Lobe; Glutamic Acid; Pregnancy; Schizophrenia	2023
The Neurobiological Underpinnings of Obsessive-Compulsive Symptoms in Psychosis, Translational Issues for Treatment-Resistant Schizophrenia. Biomolecules, 2023, 08-05, Volume: 13, Issue:8 Topics: Dopamine; Glutamic Acid; Humans; Neurobiology; Psychotic Disorders; Schizophrenia; Schizophrenia, Treatment-Resistant	2023
Cytokines and nervous system: relationship with schizophrenia Revista medica del Instituto Mexicano del Seguro Social, 2019, Jul-31, Volume: 57, Issue:2 Topics: Cytokines; Dopamine; Gene-Environment Interaction; Glutamic Acid; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Nerve Tissue Proteins; Neuregulin-1; Oxidative Stress; Schizophrenia; Schizophrenic Psychology; Serotonin; Tumor Necrosis Factor-alpha	2019
The role of glutamate and GABA in cognitive dysfunction in schizophrenia and mood disorders - A systematic review of magnetic resonance spectroscopy studies. Schizophrenia research, 2022, Volume: 249 Topics: Brain; Cognitive Dysfunction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Mood Disorders; Schizophrenia	2022
Magnetic resonance spectroscopy studies in subjects with high risk for psychosis: A meta-analysis and review. Journal of psychiatric research, 2020, Volume: 125 Topics: Aspartic Acid; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2020
Glutamate metabolites in treatment resistant schizophrenia: A meta-analysis and systematic review of Psychiatry research. Neuroimaging, 2020, 06-30, Volume: 300 Topics: Antipsychotic Agents; Brain; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2020
Treatment effects on neurometabolite levels in schizophrenia: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies. Schizophrenia research, 2020, Volume: 222 Topics: Aspartic Acid; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Thalamus	2020
Pharmacodynamic elucidation of glutamate & dopamine in ketamine-induced anaesthesia. Chemico-biological interactions, 2020, Aug-25, Volume: 327 Topics: Anesthesia; Anesthetics, Dissociative; Animals; Brain; Dopamine; Dopaminergic Neurons; Glutamic Acid; Humans; Ketamine; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2020
Metabolite abnormalities in psychosis risk: A meta-analysis of proton magnetic resonance spectroscopy studies. Asian journal of psychiatry, 2020, Volume: 54 Topics: gamma-Aminobutyric Acid; Glutamic Acid; Humans; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2020
Glutamate in schizophrenia: Neurodevelopmental perspectives and drug development. Schizophrenia research, 2020, Volume: 223 Topics: Antipsychotic Agents; Drug Development; Glutamic Acid; Humans; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2020
A Review of Molecular Imaging of Glutamate Receptors. Molecules (Basel, Switzerland), 2020, Oct-16, Volume: 25, Issue:20 Topics: Animals; Brain; Epilepsy; Glutamic Acid; Humans; Molecular Imaging; Neurodegenerative Diseases; Receptors, Glutamate; Schizophrenia; Stroke; Tomography, Emission-Computed, Single-Photon	2020
A role for endothelial NMDA receptors in the pathophysiology of schizophrenia. Schizophrenia research, 2022, Volume: 249 Topics: Aspartic Acid; Brain; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2022
Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies. International journal of molecular sciences, 2020, Dec-23, Volume: 22, Issue:1 Topics: Animals; Autism Spectrum Disorder; Biomarkers; Disease Models, Animal; Disease Susceptibility; Glutamic Acid; Humans; Mitochondria; Neuronal Plasticity; Neurons; Receptors, Glutamate; Rodentia; Schizophrenia; Synapses	2020
Memantine in neurological disorders - schizophrenia and depression. Journal of molecular medicine (Berlin, Germany), 2021, Volume: 99, Issue:3 Topics: Alzheimer Disease; Antidepressive Agents; Antipsychotic Agents; Clinical Trials as Topic; Depression; Drug Repositioning; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin 5-HT3 Receptor Antagonists	2021
Glutamate NMDA Receptor Antagonists with Relevance to Schizophrenia: A Review of Zebrafish Behavioral Studies. Current neuropharmacology, 2022, Mar-04, Volume: 20, Issue:3 Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Mammals; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Zebrafish	2022
Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data. JAMA psychiatry, 2021, 06-01, Volume: 78, Issue:6 Topics: Adult; Age Factors; Antipsychotic Agents; Biomarkers; Brain; Female; Glutamic Acid; Glutamine; Humans; Male; Patient Acuity; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2021
Beyond Dopamine Receptor Antagonism: New Targets for Schizophrenia Treatment and Prevention. International journal of molecular sciences, 2021, Apr-25, Volume: 22, Issue:9 Topics: Animals; Antipsychotic Agents; D-Amino-Acid Oxidase; Dopamine Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Molecular Targeted Therapy; Receptors, Cholinergic; Receptors, G-Protein-Coupled; Schizophrenia; Sodium Benzoate	2021
Glutamate and microglia activation as a driver of dendritic apoptosis: a core pathophysiological mechanism to understand schizophrenia. Translational psychiatry, 2021, 05-06, Volume: 11, Issue:1 Topics: Animals; Apoptosis; Dendritic Spines; Glutamic Acid; Microglia; Pyramidal Cells; Schizophrenia	2021
Not Just a Bystander: The Emerging Role of Astrocytes and Research Tools in Studying Cognitive Dysfunctions in Schizophrenia. International journal of molecular sciences, 2021, May-19, Volume: 22, Issue:10 Topics: Animals; Astrocytes; Brain; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Neuroglia; Neurons; Schizophrenia	2021
New Pharmacological Targets for the Treatment of Schizophrenia: A Literature Review. Current topics in medicinal chemistry, 2021, Oct-25, Volume: 21, Issue:16 Topics: Antipsychotic Agents; Cyclooxygenase 2 Inhibitors; Erythropoietin; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Humans; Minocycline; Molecular Targeted Therapy; Oxytocin; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2021
Medial Prefrontal Cortex Glutamate Is Reduced in Schizophrenia and Moderated by Measurement Quality: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies. Biological psychiatry, 2021, 11-01, Volume: 90, Issue:9 Topics: Glutamic Acid; Glutamine; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2021
[To Test Glutamate Hypothesis for Schizophrenia Utilizing Proton Magnetic Resonance Spectroscopy]. Brain and nerve = Shinkei kenkyu no shinpo, 2017, Volume: 69, Issue:9 Topics: Brain; Brain Chemistry; Glutamic Acid; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2017
PDE Inhibitors for the Treatment of Schizophrenia. Advances in neurobiology, 2017, Volume: 17 Topics: Antipsychotic Agents; Cognitive Dysfunction; Dopamine; Dopamine D2 Receptor Antagonists; Glutamic Acid; Humans; Phosphodiesterase Inhibitors; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology	2017
Beyond static measures: A review of functional magnetic resonance spectroscopy and its potential to investigate dynamic glutamatergic abnormalities in schizophrenia. Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:5 Topics: Glutamic Acid; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2018
Pro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin, and glutamate systems. Drug metabolism reviews, 2018, Volume: 50, Issue:1 Topics: Animals; Cannabinoids; Dopamine; Glutamic Acid; Humans; Illicit Drugs; Marijuana Abuse; Psychoses, Substance-Induced; Schizophrenia; Serotonin	2018
Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia. ACS chemical neuroscience, 2018, 09-19, Volume: 9, Issue:9 Topics: Acetylcholine; Animals; Calcium Signaling; Cognitive Dysfunction; Cyclic AMP; GABAergic Neurons; Gene-Environment Interaction; Genetic Predisposition to Disease; Glutamic Acid; Haplorhini; Humans; Interneurons; Memory, Short-Term; Neural Pathways; Prefrontal Cortex; Pyramidal Cells; Schizophrenia; Schizophrenic Psychology; Stress, Psychological	2018
Magnetic Resonance Spectroscopy in Schizophrenia: Evidence for Glutamatergic Dysfunction and Impaired Energy Metabolism. Neurochemical research, 2019, Volume: 44, Issue:1 Topics: Animals; Brain; Energy Metabolism; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Schizophrenia	2019
DARK Classics in Chemical Neuroscience: Phencyclidine (PCP). ACS chemical neuroscience, 2018, 10-17, Volume: 9, Issue:10 Topics: Glutamic Acid; Hallucinogens; History, 20th Century; History, 21st Century; Humans; Phencyclidine; Psychoses, Substance-Induced; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2018
Beyond the dopamine hypothesis of schizophrenia to three neural networks of psychosis: dopamine, serotonin, and glutamate. CNS spectrums, 2018, Volume: 23, Issue:3 Topics: Brain; Dopamine; Glutamic Acid; Humans; Psychotic Disorders; Schizophrenia; Serotonin; Synaptic Transmission	2018
Metabolomics in patients with psychosis: A systematic review. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2018, Volume: 177, Issue:6 Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan	2018
Depression and schizophrenia viewed from the perspective of amino acidergic neurotransmission: Antipodes of psychiatric disorders. Pharmacology & therapeutics, 2019, Volume: 193 Topics: Animals; Antipsychotic Agents; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Receptors, GABA; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Schizophrenia; Synaptic Transmission	2019
Current Practice and New Developments in the Use of In Vivo Magnetic Resonance Spectroscopy for the Assessment of Key Metabolites Implicated in the Pathophysiology of Schizophrenia. Current topics in medicinal chemistry, 2018, Volume: 18, Issue:21 Topics: Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Schizophrenia	2018
Glutamate hypothesis in schizophrenia. Psychiatry and clinical neurosciences, 2019, Volume: 73, Issue:5 Topics: Animals; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2019
Serotonin and Glutamate Interactions in Preclinical Schizophrenia Models. ACS chemical neuroscience, 2019, 07-17, Volume: 10, Issue:7 Topics: Animals; Brain; Disease Models, Animal; Glutamic Acid; Neurons; Schizophrenia; Serotonin	2019
Using proton magnetic resonance spectroscopic imaging to study glutamatergic alterations in patients with schizophrenia: A systematic review. Schizophrenia research, 2019, Volume: 210 Topics: Brain; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2019
Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders. European archives of psychiatry and clinical neuroscience, 2013, Volume: 263, Issue:5 Topics: Excitatory Amino Acid Agents; Glutamic Acid; Humans; Mood Disorders; Schizophrenia	2013
NMDA receptor-dependent function and plasticity in inhibitory circuits. Neuropharmacology, 2013, Volume: 74 Topics: Animals; Brain; GABAergic Neurons; Glutamic Acid; Humans; Interneurons; Models, Neurological; Neural Inhibition; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2013
SLC1 glutamate transporters and diseases: psychiatric diseases and pathological pain. Current molecular pharmacology, 2013, Volume: 6, Issue:2 Topics: Amino Acid Transport System ASC; Animals; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Minor Histocompatibility Antigens; Mood Disorders; Pain; Schizophrenia; Substance-Related Disorders; Synaptic Transmission	2013
Glutamatergic postsynaptic density protein dysfunctions in synaptic plasticity and dendritic spines morphology: relevance to schizophrenia and other behavioral disorders pathophysiology, and implications for novel therapeutic approaches. Molecular neurobiology, 2014, Volume: 49, Issue:1 Topics: Animals; Antipsychotic Agents; Child Development Disorders, Pervasive; Dendritic Spines; Disks Large Homolog 4 Protein; Drug Delivery Systems; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mental Disorders; Nerve Tissue Proteins; Neuronal Plasticity; Schizophrenia; Synapses	2014
Disruption of glutamate-glutamine-GABA cycle significantly impacts on suicidal behaviour: survey of the literature and own findings on glutamine synthetase. CNS & neurological disorders drug targets, 2013, Volume: 12, Issue:7 Topics: Brain; Case-Control Studies; Cell Count; Female; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Neuroglia; Schizophrenia; Suicide; Synaptic Transmission	2013
Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease. Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:11 Topics: Animals; Biological Transport; Central Nervous System; Epilepsy; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glutamic Acid; Homeostasis; Humans; Hypoxia; Mice; Multiple Sclerosis; Oxidative Stress; Schizophrenia; Signal Transduction	2014
Imaging glutamate in schizophrenia: review of findings and implications for drug discovery. Molecular psychiatry, 2014, Volume: 19, Issue:1 Topics: Animals; Drug Discovery; Glutamic Acid; Humans; Neuroimaging; Schizophrenia	2014
The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: further evidence and meta-analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Animals; Computational Biology; Genetic Predisposition to Disease; Glutamic Acid; Humans; Nitric Oxide; Nitric Oxide Synthase Type I; Polymorphism, Single Nucleotide; Prefrontal Cortex; Promoter Regions, Genetic; Schizophrenia; Signal Transduction; Synapses	2014
[Role of glutamate transporters in the pathophysiology of major mental illnesses]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2013, Volume: 142, Issue:6 Topics: Amino Acid Transport System X-AG; Animals; Autistic Disorder; Depressive Disorder; Disease Models, Animal; Drug Discovery; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Mice; Molecular Targeted Therapy; Mutation; Obsessive-Compulsive Disorder; Schizophrenia	2013
Intracellular signaling and approaches to the treatment of schizophrenia and associated cognitive impairment. Current pharmaceutical design, 2014, Volume: 20, Issue:31 Topics: Animals; Antipsychotic Agents; Brain; Cognition Disorders; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Glutamic Acid; Humans; Molecular Targeted Therapy; Nootropic Agents; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Schizophrenia; Schizophrenic Psychology; Signal Transduction	2014
NMDA pathology and treatment of schizophrenia. Current pharmaceutical design, 2014, Volume: 20, Issue:32 Topics: Animals; Antipsychotic Agents; Drug Design; Glutamic Acid; Humans; Molecular Targeted Therapy; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2014
Glutamatergic abnormalities in schizophrenia: a review of proton MRS findings. Schizophrenia research, 2014, Volume: 152, Issue:2-3 Topics: Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Protons; Schizophrenia	2014
The cytokine model of schizophrenia: emerging therapeutic strategies. Biological psychiatry, 2014, Feb-15, Volume: 75, Issue:4 Topics: Animals; Antipsychotic Agents; Brain; Cytokines; Dopamine; Glutamic Acid; Humans; Neuroimmunomodulation; Schizophrenia	2014
Schizophrenia: from dopaminergic to glutamatergic interventions. Current opinion in pharmacology, 2014, Volume: 14 Topics: Animals; Corpus Striatum; Dopamine; Glutamic Acid; Humans; Prefrontal Cortex; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2014
Glutamate and modeling of schizophrenia symptoms: review of our findings: 1990-2014. Pharmacological reports : PR, 2014, Volume: 66, Issue:3 Topics: Animals; Antipsychotic Agents; Cognition Disorders; Dopamine Antagonists; Glutamic Acid; Humans; Nucleus Accumbens; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2014
Clozapine augmented with glutamate modulators in refractory schizophrenia: a review and metaanalysis. Pharmacopsychiatry, 2014, Volume: 47, Issue:6 Topics: Animals; Antipsychotic Agents; Clozapine; Drug Synergism; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Schizophrenia	2014
The glutamate hypothesis: a pathogenic pathway from which pharmacological interventions have emerged. Pharmacopsychiatry, 2014, Volume: 47, Issue:4-5 Topics: Clozapine; Drug Delivery Systems; Drug Therapy, Combination; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2014
New approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways. Drug design, development and therapy, 2014, Volume: 8 Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Cell- and Tissue-Based Therapy; Deep Brain Stimulation; Dopamine; Drug Design; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Rats; Schizophrenia	2014
[NMDA-type glutamate receptor and schizophrenia]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2013, Volume: 33, Issue:5-6 Topics: Animals; Antipsychotic Agents; Brain; Glutamic Acid; Humans; Molecular Targeted Therapy; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2013
[The glutamate hypothesis of schizophrenia]. Fortschritte der Neurologie-Psychiatrie, 2014, Volume: 82, Issue:8 Topics: Dopamine; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2014
Positron emission tomography in CNS drug discovery and drug monitoring. Journal of medicinal chemistry, 2014, Nov-26, Volume: 57, Issue:22 Topics: Animals; Brain; Central Nervous System; Central Nervous System Agents; Dopamine; Drug Discovery; Drug Monitoring; Glutamic Acid; Glycolysis; Humans; Models, Chemical; Permeability; Pharmaceutical Preparations; Positron-Emission Tomography; Radioactive Tracers; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia	2014
Glutamate-mediated excitotoxicity in schizophrenia: a review. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:10 Topics: Animals; Brain; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2014
Imaging-based neurochemistry in schizophrenia: a systematic review and implications for dysfunctional long-term potentiation. Schizophrenia bulletin, 2015, Volume: 41, Issue:1 Topics: Brain; Cognition Disorders; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Long-Term Potentiation; Magnetic Resonance Spectroscopy; Positron-Emission Tomography; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	2015
The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies. Annals of the New York Academy of Sciences, 2015, Volume: 1338 Topics: Brain; Female; Glutamic Acid; Humans; Male; Receptors, Glutamate; RNA, Messenger; Schizophrenia	2015
Peripheral glutamate levels in schizophrenia: evidence from a meta-analysis. Neuropsychobiology, 2014, Volume: 70, Issue:3 Topics: Glutamic Acid; Humans; Schizophrenia	2014
MicroRNAs in Schizophrenia: Implications for Synaptic Plasticity and Dopamine-Glutamate Interaction at the Postsynaptic Density. New Avenues for Antipsychotic Treatment Under a Theranostic Perspective. Molecular neurobiology, 2015, Volume: 52, Issue:3 Topics: Animals; Antipsychotic Agents; Dopamine; Glutamic Acid; Humans; MicroRNAs; Neuronal Plasticity; Schizophrenia	2015
In the grey zone between epilepsy and schizophrenia: alterations in group II metabotropic glutamate receptors. Acta neurologica Belgica, 2015, Volume: 115, Issue:3 Topics: Animals; Brain; Epilepsy; Glutamic Acid; Humans; Receptors, Metabotropic Glutamate; Schizophrenia	2015
Glutamate and dopamine in schizophrenia: an update for the 21st century. Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:2 Topics: Animals; Antipsychotic Agents; Dopamine; Glutamic Acid; Humans; Risk Factors; Schizophrenia	2015
Drug development in schizophrenia: are glutamatergic targets still worth aiming at? Current opinion in psychiatry, 2015, Volume: 28, Issue:3 Topics: Excitatory Amino Acid Agents; Glutamic Acid; Humans; Lamotrigine; Receptors, AMPA; Receptors, Metabotropic Glutamate; Reproducibility of Results; Schizophrenia; Triazines	2015
Neurobiological background of negative symptoms. European archives of psychiatry and clinical neuroscience, 2015, Volume: 265, Issue:7 Topics: Acetylcholine; Brain; Dopamine; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Neuroimaging; Schizophrenia; Schizophrenic Psychology; Serotonin; Synaptic Transmission	2015
Glutamate synapses in human cognitive disorders. Annual review of neuroscience, 2015, Jul-08, Volume: 38 Topics: Animals; Autism Spectrum Disorder; Cognition Disorders; Genetic Predisposition to Disease; Glutamic Acid; Humans; Intellectual Disability; Models, Neurological; Schizophrenia; Synapses	2015
Glutamatergic agents for schizophrenia: current evidence and perspectives. Expert review of clinical pharmacology, 2015, Volume: 8, Issue:3 Topics: Animals; Antipsychotic Agents; Cognition Disorders; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Patient Selection; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	2015
[Role of astrocytes in alterations of glutamatergic neurotransmission in schizophrenia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:1 Topics: Antipsychotic Agents; Astrocytes; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2015
Inhibitors of Glycine Transporter-1: Potential Therapeutics for the Treatment of CNS Disorders. Current topics in medicinal chemistry, 2016, Volume: 16, Issue:29 Topics: Central Nervous System Diseases; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Humans; Schizophrenia	2016
Catatonia. CNS spectrums, 2016, Volume: 21, Issue:4 Topics: Benzodiazepines; Catatonia; Diagnostic and Statistical Manual of Mental Disorders; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Glutamic Acid; Humans; International Classification of Diseases; Mood Disorders; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology	2016
Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: A unique window into the origins of ScZ? Schizophrenia research, 2017, Volume: 180 Topics: Animals; Brain Waves; Cerebral Cortex; Glutamic Acid; Humans; Neural Pathways; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission; Thalamus	2017
Heterogeneity in Dopamine Neuron Synaptic Actions Across the Striatum and Its Relevance for Schizophrenia. Biological psychiatry, 2017, 01-01, Volume: 81, Issue:1 Topics: Animals; Corpus Striatum; Dopamine; Dopaminergic Neurons; GABAergic Neurons; Glutamic Acid; Humans; Mice; Psychotropic Drugs; Receptors, Dopamine; Schizophrenia; Synapses; Synaptic Transmission	2017
Glutamatergic dysfunction in schizophrenia: from basic neuroscience to clinical psychopharmacology. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:11 Topics: Acamprosate; Age of Onset; Antipsychotic Agents; Glutamic Acid; Humans; Neurosciences; Psychopharmacology; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission; Taurine	2008
Capitalizing on extrasynaptic glutamate neurotransmission to treat antipsychotic-resistant symptoms in schizophrenia. Biological psychiatry, 2008, Sep-01, Volume: 64, Issue:5 Topics: Antipsychotic Agents; Drug Resistance; Glutamic Acid; Humans; Schizophrenia; Synaptic Transmission	2008
The acute effects of NMDA antagonism: from the rodent to the human brain. Brain research reviews, 2009, Volume: 60, Issue:2 Topics: Animals; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neuroglia; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2009
Role of glutamate in schizophrenia: integrating excitatory avenues of research. Expert review of neurotherapeutics, 2008, Volume: 8, Issue:9 Topics: Antipsychotic Agents; Brain; Genetic Predisposition to Disease; Glutamic Acid; Humans; Receptors, Metabotropic Glutamate; Schizophrenia	2008
Interaction between N-methyl-D-aspartic acid receptors and D1 dopamine receptors: an important mechanism for brain plasticity. Neuroscience, 2009, Jan-12, Volume: 158, Issue:1 Topics: Animals; Brain; Dopamine; Glutamic Acid; Humans; Neuronal Plasticity; Protein Transport; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses; Synaptic Transmission	2009
Inflammation and the glutamate system in schizophrenia: implications for therapeutic targets and drug development. Expert opinion on therapeutic targets, 2008, Volume: 12, Issue:12 Topics: Antipsychotic Agents; Glutamic Acid; Humans; Inflammation; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2008
Psychedelics and schizophrenia. Trends in neurosciences, 2009, Volume: 32, Issue:4 Topics: Animals; Glutamic Acid; Hallucinogens; Humans; Models, Neurological; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Agonists	2009
Glutamate and dopamine components in schizophrenia. Journal of psychiatry & neuroscience : JPN, 2009, Volume: 34, Issue:2 Topics: Animals; Disease Models, Animal; Dopamine; Dopamine Agonists; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Receptors, Dopamine D2; Receptors, Glutamate; Schizophrenia	2009
When doors of perception close: bottom-up models of disrupted cognition in schizophrenia. Annual review of clinical psychology, 2009, Volume: 5 Topics: Brain; Cognition Disorders; Evoked Potentials, Visual; Glutamic Acid; Humans; Magnetic Resonance Imaging; Memory, Short-Term; Perceptual Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Verbal Behavior	2009
Antipsychotics in the early stage of development. Current opinion in psychiatry, 2009, Volume: 22, Issue:3 Topics: Antipsychotic Agents; Dopamine; Glutamic Acid; Humans; Ketamine; Phencyclidine; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Receptors, Serotonin; Schizophrenia; Serotonin; Severity of Illness Index; Synaptic Transmission	2009
Using the pharmacology of latent inhibition to model domains of pathology in schizophrenia and their treatment. Behavioural brain research, 2009, Dec-07, Volume: 204, Issue:2 Topics: Acetylcholine; Animals; Attention; Disease Models, Animal; Dopamine; Glutamic Acid; Memory; Mice; Neural Inhibition; Rats; Schizophrenia; Schizophrenic Psychology	2009
Cognitive dysfunction in schizophrenia: a perspective from the clinic to genetic brain mechanisms. Annals of the Academy of Medicine, Singapore, 2009, Volume: 38, Issue:5 Topics: Cognition Disorders; Dopamine; Glutamic Acid; Humans; Magnetic Resonance Imaging; Neurosciences; Schizophrenia	2009
Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: therapeutic implications. Journal of neurochemistry, 2009, Volume: 111, Issue:4 Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interneurons; Models, Neurological; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction	2009
Imaging the glutamate system in humans: relevance to drug discovery for schizophrenia. Current pharmaceutical design, 2009, Volume: 15, Issue:22 Topics: Brain; Drug Delivery Systems; Drug Discovery; Glutamic Acid; Humans; Ketamine; Magnetic Resonance Spectroscopy; Models, Neurological; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2009
What do ERPs and ERFs reveal about the effect of antipsychotic treatment on cognition in schizophrenia? Current pharmaceutical design, 2009, Volume: 15, Issue:22 Topics: Antipsychotic Agents; Brain; Cognition; Dopamine; Electroencephalography; Evoked Potentials; Evoked Potentials, Auditory; Glutamic Acid; Humans; Magnetoencephalography; Psychotropic Drugs; Schizophrenia; Schizophrenic Psychology	2009
Epigenetic mediation of environmental influences in major psychotic disorders. Schizophrenia bulletin, 2009, Volume: 35, Issue:6 Topics: Alleles; Bipolar Disorder; Child; Child Abuse; Diseases in Twins; DNA Methylation; Epigenesis, Genetic; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Humans; Illicit Drugs; Parenting; Phenotype; Polymorphism, Genetic; Pregnancy; Prenatal Exposure Delayed Effects; Psychoses, Substance-Induced; Risk Factors; Schizophrenia; Schizophrenic Psychology; Social Environment	2009
Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop. Acta psychiatrica Scandinavica, 2009, Volume: 120, Issue:5 Topics: Cell Count; Glutamic Acid; Humans; Mediodorsal Thalamic Nucleus; Schizophrenia; Synaptic Transmission; Thalamus	2009
Recent patents on positive allosteric modulators of the metabotropic glutamate 5 receptor as a potential treatment for schizophrenia. Recent patents on CNS drug discovery, 2010, Volume: 5, Issue:1 Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Models, Biological; Patents as Topic; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Schizophrenia	2010
Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects. Schizophrenia bulletin, 2010, Volume: 36, Issue:2 Topics: Animals; Brain; Disease Models, Animal; Dopamine; Genetic Association Studies; Glutamic Acid; Humans; Mice; Mice, Mutant Strains; Motor Activity; Phenotype; Psychotropic Drugs; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Sensory Gating	2010
Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: a decade of advance. Neuroscience and biobehavioral reviews, 2010, Volume: 34, Issue:6 Topics: Animals; Bipolar Disorder; gamma-Aminobutyric Acid; Genetic Association Studies; Glutamic Acid; Humans; Schizophrenia; Synaptic Transmission	2010
Mutant mouse models: phenotypic relationships to domains of psychopathology and pathobiology in schizophrenia. Schizophrenia bulletin, 2010, Volume: 36, Issue:2 Topics: Animals; Brain; Cognition Disorders; Disease Models, Animal; DNA Mutational Analysis; Dopamine; Genetic Association Studies; Genetic Linkage; Glutamic Acid; Humans; Mice; Mice, Mutant Strains; Phenotype; Schizophrenia; Schizophrenic Psychology	2010
[Recent discoveries on the function and plasticity of central dopamine pathways]. Medecine sciences : M/S, 2010, Volume: 26, Issue:2 Topics: Animals; Brain; Dopamine; Glutamic Acid; Humans; Models, Neurological; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Neurons; Parkinson Disease; Receptors, Dopamine; Schizophrenia; Signal Transduction; Substantia Nigra; Synaptic Transmission; Ventral Tegmental Area	2010
NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia. Progress in brain research, 2009, Volume: 179 Topics: Animals; Brain Chemistry; Down-Regulation; Glutamic Acid; Mice; Mice, Knockout; Mutation; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2009
Glutamatergic theories of schizophrenia. The Israel journal of psychiatry and related sciences, 2010, Volume: 47, Issue:1 Topics: Animals; Brain; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ketamine; Nerve Net; Phencyclidine; Prefrontal Cortex; Psychological Theory; Receptors, Dopamine D2; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission	2010
Significance of NMDA receptor-related glutamatergic amino acid levels in peripheral blood of patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1 Topics: Amino Acids; Antipsychotic Agents; Glutamic Acid; Humans; MEDLINE; Nutritional Status; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2011
Alterations in dopamine and glutamate neurotransmission in tetrahydrobiopterin deficient spr-/- mice: relevance to schizophrenia. BMB reports, 2010, Volume: 43, Issue:9 Topics: Alcohol Oxidoreductases; Animals; Biopterins; Dopamine; Glutamic Acid; Humans; Mice; Models, Biological; Schizophrenia; Synaptic Transmission	2010
Thinking glutamatergically: changing concepts of schizophrenia based upon changing neurochemical models. Clinical schizophrenia & related psychoses, 2010, Volume: 4, Issue:3 Topics: Brain; Glutamic Acid; Humans; Models, Chemical; Models, Neurological; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2010
[Targeting metabotropic glutamate receptors to develop novel antipsychotics]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2010, Volume: 30, Issue:5-6 Topics: Amino Acids; Animals; Antipsychotic Agents; Clinical Trials, Phase II as Topic; Disease Models, Animal; Dopamine; Drug Design; Glutamic Acid; Humans; Molecular Targeted Therapy; Receptor, Metabotropic Glutamate 5; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; Schizophrenia	2010
Contributions of the D-serine pathway to schizophrenia. Neuropharmacology, 2012, Volume: 62, Issue:3 Topics: Animals; Glutamic Acid; Humans; Mice; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Signal Transduction	2012
Targeting of metabotropic glutamate receptors for the treatment of schizophrenia. Current pharmaceutical design, 2011, Volume: 17, Issue:2 Topics: Animals; Antipsychotic Agents; Brain; Glutamic Acid; Humans; Mice; Molecular Targeted Therapy; Rats; Receptors, Metabotropic Glutamate; Schizophrenia; Synaptic Transmission	2011
Postnatal developmental trajectories of neural circuits in the primate prefrontal cortex: identifying sensitive periods for vulnerability to schizophrenia. Schizophrenia bulletin, 2011, Volume: 37, Issue:3 Topics: Adolescent; Adolescent Development; Age of Onset; Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Macaca; Neural Pathways; Prefrontal Cortex; Risk Factors; Schizophrenia	2011
Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood-brain barrier integrity. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2012, Volume: 13, Issue:7 Topics: Blood-Brain Barrier; Depressive Disorder, Major; Glutamic Acid; Humans; Inflammation; Kynurenine; Neuroglia; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2012
Glutamate in schizophrenia: a focused review and meta-analysis of ¹H-MRS studies. Schizophrenia bulletin, 2013, Volume: 39, Issue:1 Topics: Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Schizophrenia	2013
The role of the cerebellum in schizophrenia: from cognition to molecular pathways. Clinics (Sao Paulo, Brazil), 2011, Volume: 66 Suppl 1 Topics: Animals; Antipsychotic Agents; Cerebellum; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2011
From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:1 Topics: Glutamic Acid; Humans; Neurotransmitter Agents; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2012
Origins and perspectives of schizophrenia research. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2011, Volume: 13, Issue:4 Topics: Biomedical Research; Dopamine; Fetal Development; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Schizophrenia; Serotonin	2011
[PolyI:C-induced neurodevelopmental animal model for schizophrenia]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2011, Volume: 31, Issue:5-6 Topics: Animals; Disease Models, Animal; Gene-Environment Interaction; Glutamic Acid; Hippocampus; Humans; Ligands; Mice; Nerve Tissue Proteins; Neurogenesis; Poly I-C; Schizophrenia; Toll-Like Receptor 3	2011
The glutamate hypothesis of schizophrenia: neuroimaging and drug development. Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:8 Topics: Animals; Diagnostic Imaging; Drug Design; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2012
From glutamatergic dysfunction to cognitive impairment: boundaries in the therapeutic of the schizophrenia. Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:8 Topics: Cognition Disorders; Glutamic Acid; Humans; Receptors, Glutamate; Schizophrenia	2012
Recent advances in targeting the ionotropic glutamate receptors in treating schizophrenia. Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:8 Topics: Antipsychotic Agents; Glutamic Acid; Humans; Receptors, Ionotropic Glutamate; Schizophrenia	2012
Glutamatergic transmission in schizophrenia: from basic research to clinical practice. Current opinion in psychiatry, 2012, Volume: 25, Issue:2 Topics: Animals; Antipsychotic Agents; Biomarkers; Clinical Trials as Topic; Glutamic Acid; Humans; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Thalamus	2012
Synaptic dysfunction in schizophrenia. Advances in experimental medicine and biology, 2012, Volume: 970 Topics: Acetylcholine; Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Glutamic Acid; Humans; Mice; Mutation; Nerve Tissue Proteins; Neuronal Plasticity; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA; Receptors, Glutamate; Schizophrenia; Synapses; Synaptic Transmission	2012
NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia. Schizophrenia bulletin, 2012, Volume: 38, Issue:5 Topics: Animals; Awareness; Cerebral Cortex; Cholecystokinin; Cognition Disorders; Cortical Synchronization; Electroencephalography; Glutamic Acid; Humans; Interneurons; Nerve Net; Neural Inhibition; Neuronal Plasticity; Neurons; Parvalbumins; Pyramidal Cells; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction; Synaptic Transmission	2012
Targeting glutamate system for novel antipsychotic approaches: relevance for residual psychotic symptoms and treatment resistant schizophrenia. European journal of pharmacology, 2012, May-05, Volume: 682, Issue:1-3 Topics: Animals; Antipsychotic Agents; Drug Resistance; Glutamic Acid; Humans; Molecular Targeted Therapy; Psychotic Disorders; Schizophrenia	2012
Glutamate dysfunction in hippocampus: relevance of dentate gyrus and CA3 signaling. Schizophrenia bulletin, 2012, Volume: 38, Issue:5 Topics: Anxiety; Arousal; Association; Brain; CA3 Region, Hippocampal; Dentate Gyrus; Glutamic Acid; Hippocampus; Humans; Memory; Neural Pathways; Neuronal Plasticity; Neurons; Schizophrenia; Schizophrenic Psychology; Signal Transduction; Stress, Psychological; Synapses; Synaptic Transmission	2012
Drugs of abuse and increased risk of psychosis development. The Australian and New Zealand journal of psychiatry, 2012, Volume: 46, Issue:12 Topics: Age of Onset; Animals; Behavioral Symptoms; Brain; Cannabis; Dopamine; Dopamine Uptake Inhibitors; Functional Neuroimaging; Genetic Predisposition to Disease; Glutamic Acid; Humans; Illicit Drugs; Methamphetamine; Models, Animal; Psychoses, Substance-Induced; Risk Factors; Schizophrenia; Substance-Related Disorders	2012
Capturing the angel in "angel dust": twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans. Schizophrenia bulletin, 2012, Volume: 38, Issue:5 Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Brief Psychiatric Rating Scale; Cerebral Cortex; Disease Models, Animal; Dopamine; Emotions; Glutamic Acid; Humans; Ketamine; Neurosciences; Phencyclidine; Psychoses, Substance-Induced; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses; Translational Research, Biomedical	2012
Reliable biomarkers and predictors of schizophrenia and its treatment. The Psychiatric clinics of North America, 2012, Volume: 35, Issue:3 Topics: Biomarkers; Brain-Derived Neurotrophic Factor; Carrier Proteins; Dopamine; Dysbindin; Dystrophin-Associated Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Nerve Tissue Proteins; Neuregulins; Precision Medicine; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins c-akt; Schizophrenia; Signal Transduction	2012
Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications. Handbook of experimental pharmacology, 2012, Issue:213 Topics: Animals; Cognition; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ketamine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses; Synaptic Transmission	2012
The dopamine dysfunction in schizophrenia revisited: new insights into topography and course. Handbook of experimental pharmacology, 2012, Issue:212 Topics: Animals; Cognition; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Receptors, Dopamine D2; Schizophrenia	2012
Animal models of schizophrenia for molecular and pharmacological intervention and potential candidate molecules. Neurobiology of disease, 2013, Volume: 53 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Neuregulin-1; Schizophrenia; Treatment Outcome	2013
Serotonin-glutamate and serotonin-dopamine reciprocal interactions as putative molecular targets for novel antipsychotic treatments: from receptor heterodimers to postsynaptic scaffolding and effector proteins. Psychopharmacology, 2013, Volume: 225, Issue:1 Topics: Animals; Antipsychotic Agents; Dopamine; Glutamic Acid; Humans; Molecular Targeted Therapy; Nerve Tissue Proteins; Receptors, Dopamine; Receptors, Glutamate; Receptors, Serotonin; Schizophrenia; Serotonin; Signal Transduction	2013
Emerging approaches for treatment of schizophrenia: modulation of glutamatergic signaling. Discovery medicine, 2012, Volume: 14, Issue:78 Topics: Antipsychotic Agents; Glutamic Acid; Humans; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction	2012
Neuroimaging correlates of 22q11.2 deletion syndrome: implications for schizophrenia research. Current topics in medicinal chemistry, 2012, Volume: 12, Issue:21 Topics: Brain; Catechol O-Methyltransferase; Diffusion Tensor Imaging; DiGeorge Syndrome; Genetic Predisposition to Disease; Glutamic Acid; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Molecular Imaging; Neuroimaging; Proline Oxidase; Schizophrenia	2012
The concept of salience network dysfunction in schizophrenia: from neuroimaging observations to therapeutic opportunities. Current topics in medicinal chemistry, 2012, Volume: 12, Issue:21 Topics: Cerebral Cortex; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Neuroimaging; Psychotic Disorders; Risk Factors; Schizophrenia; Schizophrenic Psychology	2012
Topiramate in schizophrenia: a review of effects on psychopathology and metabolic parameters. Clinical schizophrenia & related psychoses, 2013, Volume: 6, Issue:4 Topics: Anticonvulsants; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Metabolic Diseases; Neuropsychological Tests; Schizophrenia; Schizophrenic Psychology; Topiramate; Weight Gain	2013
Hippocampal neurons in schizophrenia. Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:5-6 Topics: gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Nerve Tissue Proteins; Neurons; Schizophrenia; Synapses	2002
Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders. Progress in neurobiology, 2002, Volume: 67, Issue:3 Topics: Bipolar Disorder; Brain; Depressive Disorder; Dopamine; Glutamic Acid; Humans; Limbic System; Neurotransmitter Agents; Norepinephrine; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia; Serotonin	2002
Antischizophrenic activity independent of dopamine D2 blockade. Expert opinion on therapeutic targets, 2002, Volume: 6, Issue:5 Topics: Amino Acid Transport System X-AG; Animals; Antipsychotic Agents; Brain Chemistry; Dopamine D2 Receptor Antagonists; Drug Design; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Frontal Lobe; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Interneurons; Ketamine; Lamotrigine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Schizophrenia; Symporters; Triazines	2002
[Pathogenesis and heterogeneity in schizophrenia]. Ryoikibetsu shokogun shirizu, 2003, Issue:38 Topics: Brain; Dopamine; Female; Genetic Heterogeneity; Glutamic Acid; Humans; Influenza, Human; Multifactorial Inheritance; Pregnancy; Pregnancy Complications; Schizophrenia; Seasons; Serotonin	2003
NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology, 2003, Volume: 169, Issue:3-4 Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Cognition; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ketamine; Models, Neurological; Neural Pathways; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2003
The genetics of schizophrenia: glutamate not dopamine? European journal of pharmacology, 2003, Nov-07, Volume: 480, Issue:1-3 Topics: Animals; Dopamine; Genetic Linkage; Genetic Predisposition to Disease; Glutamic Acid; Humans; Schizophrenia	2003
[Sensitization phenomenon]. Ryoikibetsu shokogun shirizu, 2003, Issue:40 Topics: Amphetamine-Related Disorders; Animals; Brain; Chronic Disease; Corpus Striatum; Dopamine; Drug Tolerance; Glutamic Acid; Humans; Neuronal Plasticity; Schizophrenia; Stereotyped Behavior; Stereotypic Movement Disorder	2003
Bringing order to the glutamate chaos in schizophrenia. Neuron, 2003, Dec-04, Volume: 40, Issue:5 Topics: Animals; Antipsychotic Agents; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2003
Electrophysiological interactions between striatal glutamatergic and dopaminergic systems. Annals of the New York Academy of Sciences, 2003, Volume: 1003 Topics: Animals; Dopamine; Electrophysiology; Glutamic Acid; Humans; Mental Processes; Mesencephalon; Neostriatum; Neurons, Afferent; Schizophrenia; Synaptic Transmission	2003
[Hypoglutamatergic hypothesis of schizophrenia: evidence from genetic studies]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2003, Volume: 105, Issue:11 Topics: Genetic Linkage; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2003
Schizophrenia: from dopamine to glutamate and back. Current medicinal chemistry, 2004, Volume: 11, Issue:3 Topics: Animals; Antipsychotic Agents; Aripiprazole; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Mice; Piperazines; Piperidines; Quinolones; Schizophrenia	2004
Neuregulin 1 and schizophrenia. Annals of medicine, 2004, Volume: 36, Issue:1 Topics: Animals; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Glutamic Acid; Humans; Mice; Mice, Knockout; Molecular Sequence Data; Neuregulin-1; Paracrine Communication; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2004
NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia. International review of neurobiology, 2004, Volume: 59 Topics: Anesthetics; Animals; Clinical Trials as Topic; Glutamic Acid; Glycine; Humans; Models, Neurological; Neuronal Plasticity; Postmortem Changes; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2004
Dopamine and glutamate dysfunctions in schizophrenia: role of the dopamine D3 receptor. Neurotoxicity research, 2004, Volume: 6, Issue:1 Topics: Brain Chemistry; Dopamine; Glutamic Acid; Humans; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia	2004
Animal models of working memory: insights for targeting cognitive dysfunction in schizophrenia. Psychopharmacology, 2004, Volume: 174, Issue:1 Topics: Amphetamine; Animals; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Memory, Short-Term; Models, Animal; Phencyclidine; Prefrontal Cortex; Schizophrenia	2004
The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology, 2004, Volume: 174, Issue:1 Topics: Animals; Functional Laterality; Glutamic Acid; Hippocampus; Humans; Neurons; Schizophrenia; Synapses	2004
Glutamate as a therapeutic target in psychiatric disorders. Molecular psychiatry, 2004, Volume: 9, Issue:11 Topics: Animals; Disease Models, Animal; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mental Disorders; Phencyclidine; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2004
Glutamate co-transmission as an emerging concept in monoamine neuron function. Journal of psychiatry & neuroscience : JPN, 2004, Volume: 29, Issue:4 Topics: Biogenic Monoamines; Brain; Dopamine; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neurons; Schizophrenia; Serotonin; Synaptic Transmission	2004
Phenotype of schizophrenia: a review and formulation. Molecular psychiatry, 2005, Volume: 10, Issue:1 Topics: Behavioral Symptoms; Biogenic Monoamines; Brain; Brain Chemistry; Genetic Predisposition to Disease; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Limbic System; Models, Neurological; Phenotype; Schizophrenia; Schizophrenic Psychology	2005
N-methyl-D-aspartate antagonists as drug models of schizophrenia: a surprising link to tobacco smoking. Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:5 Topics: Animals; Brain Chemistry; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Models, Biological; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Smoking	2004
Thalamic dysfunction in schizophrenia: neurochemical, neuropathological, and in vivo imaging abnormalities. Schizophrenia research, 2004, Aug-01, Volume: 69, Issue:2-3 Topics: Animals; Brain Chemistry; Cell Count; Diagnostic Imaging; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; In Situ Hybridization; Models, Neurological; Postmortem Changes; Schizophrenia; Thalamus	2004
The basal ganglia: anatomy, physiology, and pharmacology. The Psychiatric clinics of North America, 2004, Volume: 27, Issue:4 Topics: Acetylcholine; Basal Ganglia; Cognition Disorders; Corpus Striatum; Frontal Lobe; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Humans; Nerve Net; Positron-Emission Tomography; Rest; Schizophrenia; Serotonin; Substantia Nigra; Thalamus	2004
Implications for atypical antipsychotics in the treatment of schizophrenia: neurocognition effects and a neuroprotective hypothesis. Pharmacotherapy, 2004, Volume: 24, Issue:12 Topics: Alzheimer Disease; Animals; Antipsychotic Agents; Apoptosis; Catechol O-Methyltransferase; Cognition; Cognition Disorders; Drug Therapy, Combination; Glutamic Acid; Hippocampus; Humans; Neuroprotective Agents; Prefrontal Cortex; Psychotic Disorders; Schizophrenia	2004
Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. European psychiatry : the journal of the Association of European Psychiatrists, 2005, Volume: 20, Issue:1 Topics: Antipsychotic Agents; Brain; Dopamine; Glutamic Acid; Humans; N-Methylaspartate; Positron-Emission Tomography; Receptors, Dopamine D1; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2005
[In search of susceptibility genes for schizophrenia]. Wiener klinische Wochenschrift, 2004, Dec-30, Volume: 116, Issue:24 Topics: Abnormalities, Multiple; Adult; Animals; Brain; Catechol O-Methyltransferase; Chromosome Aberrations; Chromosomes, Human, Pair 22; Face; Gene Expression; Genetic Linkage; Genetic Predisposition to Disease; Glutamic Acid; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Mice; Mice, Knockout; Neuregulin-1; Palate, Soft; Proline Oxidase; RGS Proteins; Risk Factors; Schizophrenia; Syndrome	2004
On the trail of a cognitive enhancer for the treatment of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:2 Topics: Acetylcholine; Animals; Antipsychotic Agents; Cognition; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Nootropic Agents; Norepinephrine; Psychopharmacology; Schizophrenia	2005
Glutamate transporters as drug targets. Current drug targets. CNS and neurological disorders, 2005, Volume: 4, Issue:2 Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Brain Ischemia; Drug Design; Epilepsy; Glutamic Acid; Humans; Membrane Transport Proteins; Schizophrenia; Transport Vesicles	2005
Hypothesis: minimal changes in neural transmission in schizophrenia: decreased glutamatergic and GABAergic functions in the prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:6 Topics: Animals; Brain Chemistry; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; Prefrontal Cortex; Schizophrenia; Synaptic Transmission	2005
Developmental pathology, dopamine, and stress: a model for the age of onset of schizophrenia symptoms. Schizophrenia bulletin, 2004, Volume: 30, Issue:4 Topics: Adolescent; Age of Onset; Brain; Child; Developmental Disabilities; Dopamine; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Interpersonal Relations; Pituitary-Adrenal System; Schizophrenia; Social Behavior; Stress, Psychological	2004
The potential role of lamotrigine in schizophrenia. Psychopharmacology, 2005, Volume: 181, Issue:3 Topics: Animals; Anticonvulsants; Antipsychotic Agents; Brain; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Glutamic Acid; Humans; Lamotrigine; Rats; Schizophrenia; Schizophrenic Psychology; Triazines	2005
Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia. Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:9 Topics: Animals; Aspartic Acid; Brain; Dipeptides; Glutamic Acid; Humans; Models, Neurological; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2005
Mechanism of action of antipsychotic drugs: from dopamine D(2) receptor antagonism to glutamate NMDA facilitation. Clinical therapeutics, 2005, Volume: 27 Suppl A Topics: Antipsychotic Agents; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2005
Glutamatergic hypothesis of schizophrenia: involvement of Na+/K+-dependent glutamate transport. Journal of biomedical science, 2005, Volume: 12, Issue:6 Topics: Animals; Biological Transport; Central Nervous System; Gene Expression Regulation, Enzymologic; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamic Acid; Glutamine; Humans; Models, Biological; Neurotransmitter Agents; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; Sodium-Potassium-Exchanging ATPase; Synapses	2005
Glutamatergic neurotransmission modulators as emerging new drugs for schizophrenia. Expert opinion on emerging drugs, 2005, Volume: 10, Issue:4 Topics: Animals; Drugs, Investigational; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Receptors, Glutamate; Schizophrenia; Synaptic Transmission	2005
Dopaminergic control of working memory and its relevance to schizophrenia: a circuit dynamics perspective. Neuroscience, 2006, Apr-28, Volume: 139, Issue:1 Topics: Dopamine; Glutamic Acid; Humans; Memory Disorders; Memory, Short-Term; Mesencephalon; Neural Inhibition; Neural Pathways; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission	2006
[Brain of patients with chronic schizophrenia and neurotransmitters]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:10 Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, Dopamine D2; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Substance P; Tyrosine 3-Monooxygenase	2005
Role of central glutamatergic neurotransmission in the pathogenesis of psychiatric and behavioral disorders. Drug news & perspectives, 2005, Volume: 18, Issue:9 Topics: Animals; Antipsychotic Agents; Brain; Dopamine; Glutamic Acid; Humans; Mental Disorders; Receptors, Glutamate; Schizophrenia; Synaptic Transmission	2005
Synaptic plasticity and dysconnection in schizophrenia. Biological psychiatry, 2006, May-15, Volume: 59, Issue:10 Topics: Acetylcholine; Brain; Brain Mapping; Contingent Negative Variation; Dopamine; Electroencephalography; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Nerve Fibers; Nerve Net; Neuronal Plasticity; Schizophrenia; Synapses	2006
[Dreaming and schizophrenia: a common neurobiological background?]. Medecine sciences : M/S, 2006, Volume: 22, Issue:2 Topics: Animals; Dopamine; Dreams; Glutamic Acid; Hallucinations; Humans; Models, Neurological; Models, Psychological; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Serotonin; Sleep Stages; Sleep, REM; Wakefulness	2006
What have we learned from proton magnetic resonance spectroscopy about schizophrenia? A critical update. Current opinion in psychiatry, 2006, Volume: 19, Issue:2 Topics: Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Cross-Over Studies; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Protons; Schizophrenia; Temporal Lobe	2006
Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients. Current opinion in psychiatry, 2006, Volume: 19, Issue:2 Topics: Antimetabolites; Antipsychotic Agents; Clozapine; Cycloserine; Drug Therapy, Combination; Glutamic Acid; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia	2006
Major affective disorders and schizophrenia: a common molecular signature? Human mutation, 2006, Volume: 27, Issue:9 Topics: Dopamine; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Humans; Mood Disorders; Neurons; Risk Factors; Schizophrenia; Serotonin; Signal Transduction	2006
Pathophysiologically based treatment interventions in schizophrenia. Nature medicine, 2006, Volume: 12, Issue:9 Topics: Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Memory Disorders; Models, Neurological; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2006
Possible mechanisms of neurodegeneration in schizophrenia. Neurochemical research, 2006, Volume: 31, Issue:10 Topics: Antipsychotic Agents; Brain; Dopamine; Glutamic Acid; Humans; Neurodegenerative Diseases; Nitric Oxide; Schizophrenia	2006
Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations. Archives of neurology, 2006, Volume: 63, Issue:10 Topics: Animals; Cognition Disorders; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Inhibition; Prefrontal Cortex; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2006
Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission. Neurotoxicity research, 2006, Volume: 10, Issue:2 Topics: Animals; Glutamic Acid; Humans; Immune System; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2006
How do glial-neuronal interactions fit into current neurotransmitter hypotheses of schizophrenia? Neurochemistry international, 2007, Volume: 50, Issue:2 Topics: Animals; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neuroglia; Neurons; Neurotransmitter Agents; Schizophrenia	2007
Animal model of schizophrenia: dysfunction of NMDA receptor-signaling in mice following withdrawal from repeated administration of phencyclidine. Annals of the New York Academy of Sciences, 2006, Volume: 1086 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cognition; Disease Models, Animal; Glutamic Acid; Mice; Motor Activity; Phencyclidine; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Signal Transduction	2006
D-serine: a new word in the glutamatergic neuro-glial language. Amino acids, 2007, Volume: 33, Issue:4 Topics: Alzheimer Disease; Animals; Astrocytes; Cell Death; Cell Movement; Glutamic Acid; Humans; Neuroglia; Neurons; Neurotransmitter Agents; Schizophrenia; Serine; Synapses; Synaptic Transmission	2007
Reviewing the role of the genes G72 and DAAO in glutamate neurotransmission in schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:9 Topics: Carrier Proteins; D-Amino-Acid Oxidase; Genetic Predisposition to Disease; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Models, Biological; Schizophrenia; Synaptic Transmission	2007
Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions. International review of neurobiology, 2007, Volume: 78 Topics: Animals; Antipsychotic Agents; Brain; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Phencyclidine; Psychoses, Substance-Induced; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2007
Comorbidity of substance abuse with other psychiatric disorders. Neurotoxicity research, 2007, Volume: 12, Issue:1 Topics: Cerebral Ventricles; Comorbidity; Glutamic Acid; Humans; Mental Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Substance-Related Disorders; Synaptic Transmission	2007
Phencyclidine and genetic animal models of schizophrenia developed in relation to the glutamate hypothesis. Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:4 Topics: Animals; Behavior, Animal; Calcineurin; Cognition; Disease Models, Animal; Gait; Glutamic Acid; Humans; Inhibition, Psychological; Mice; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Neuregulin-1; Phencyclidine; Receptors, Lysophosphatidic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Social Behavior	2007
Novel targets for drugs in schizophrenia. CNS & neurological disorders drug targets, 2007, Volume: 6, Issue:4 Topics: Animals; Antipsychotic Agents; Brain Chemistry; Dyskinesia, Drug-Induced; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia	2007
Homers regulate drug-induced neuroplasticity: implications for addiction. Biochemical pharmacology, 2008, Jan-01, Volume: 75, Issue:1 Topics: Animals; Carrier Proteins; Cocaine; Ethanol; Glutamic Acid; Homer Scaffolding Proteins; Humans; Methamphetamine; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Schizophrenia; Substance-Related Disorders	2008
[Development of new drugs targeting glial cells]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 130, Issue:3 Topics: Animals; Astrocytes; Central Nervous System Agents; Cytokines; Drug Design; Glutamic Acid; Humans; Neuroglia; Neurotransmitter Agents; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Schizophrenia	2007
The role of cortical inhibition in the pathophysiology and treatment of schizophrenia. Brain research reviews, 2007, Volume: 56, Issue:2 Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interneurons; Schizophrenia	2007
Molecular mechanisms of schizophrenia. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 20, Issue:6 Topics: Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; Phosphatidylinositol 3-Kinases; Reelin Protein; Schizophrenia	2007
Nicotine and nicotinic system in hypoglutamatergic models of schizophrenia. Neurotoxicity research, 2007, Volume: 12, Issue:4 Topics: Animals; Disease Models, Animal; Electrophysiology; Glutamic Acid; Humans; Nicotine; Receptors, Nicotinic; Schizophrenia; Schizophrenic Psychology; Smoking	2007
Glycine transporter inhibitors as therapeutic agents for schizophrenia. Recent patents on CNS drug discovery, 2006, Volume: 1, Issue:1 Topics: Animals; Benzamides; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Piperidines; Schizophrenia	2006
Glutamatergic abnormalities of the thalamus in schizophrenia: a systematic review. Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:3 Topics: Amino Acid Transport System X-AG; Animals; Glutamic Acid; Humans; Receptors, Glutamate; Schizophrenia; Thalamus	2008
Maturation-dependent sensitivity of oligodendrocyte lineage cells to apoptosis: implications for normal development and disease. Cell death and differentiation, 2008, Volume: 15, Issue:7 Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Brain Diseases; Cell Differentiation; Cell Lineage; Cell Survival; Central Nervous System; Glutamic Acid; Humans; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Reactive Oxygen Species; Schizophrenia	2008
Chemistry, physiology and neuropsychology of schizophrenia: towards an earlier diagnosis of schizophrenia I. Archiv fur Psychiatrie und Nervenkrankheiten, 1983, Volume: 233, Issue:6 Topics: Child; Dopamine; Electroencephalography; Glutamates; Glutamic Acid; Humans; Reaction Time; Receptors, Dopamine; Saccades; Schizophrenia	1983
Neuropsychological implications of brain changes in schizophrenia: an overview. Psychopathology, 1994, Volume: 27, Issue:3-5 Topics: Awareness; Brain; Brain Damage, Chronic; Dominance, Cerebral; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neurocognitive Disorders; Neuropsychological Tests; Schizophrenia; Schizophrenic Psychology	1994
Schizophrenia: neurobiological perspectives. Progress in brain research, 1994, Volume: 100 Topics: Glutamic Acid; Humans; Neuronal Plasticity; Schizophrenia; Synaptic Transmission	1994
Schizophrenia as a brain disease. Archives of neurology, 1993, Volume: 50, Issue:10 Topics: Brain Diseases; Dopamine; Glutamates; Glutamic Acid; Humans; Magnetic Resonance Imaging; Schizophrenia; Temporal Lobe	1993
The phencyclidine-glutamate model of schizophrenia. Clinical neuropharmacology, 1995, Volume: 18, Issue:3 Topics: Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Phencyclidine; Schizophrenia	1995
[Role of excitatory amino acids in neuropathology]. Medicina, 1995, Volume: 55, Issue:4 Topics: Animals; Epilepsy; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ischemia; Neuroglia; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	1995
Cognitive function in schizophrenic patients. The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 11 Topics: Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Clozapine; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Limbic System; Olanzapine; Pirenzepine; Schizophrenia; Schizophrenic Psychology; Serotonin	1996
A pivotal role for glutamate in the pathogenesis of schizophrenia, and its cognitive dysfunction. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:4 Topics: Animals; Cognition Disorders; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology	1997
Neurotransmitter aberrations in schizophrenia: new perspectives and therapeutic implications. Life sciences, 1997, Volume: 61, Issue:2 Topics: Animals; Antipsychotic Agents; Brain; Corpus Striatum; Dopamine; Glutamic Acid; Humans; Neurotransmitter Agents; Norepinephrine; Schizophrenia; Serotonin; Synaptic Transmission; Thalamus	1997
Familial and developmental abnormalities of front lobe function and neurochemistry in schizophrenia. Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:2 Topics: Antipsychotic Agents; Brain Mapping; Frontal Lobe; Glutamic Acid; Humans; Neural Pathways; Neurotransmitter Agents; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Temporal Lobe	1997
The biological basis of schizophrenia: new directions. The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 10 Topics: Animals; Aspartic Acid; Brain; Cholecystokinin; Disease Models, Animal; Dopamine; Entorhinal Cortex; gamma-Aminobutyric Acid; Genetic Linkage; Genetic Markers; Glutamic Acid; Humans; RNA, Messenger; Rodentia; Schizophrenia	1997
Functional and anatomical aspects of prefrontal pathology in schizophrenia. Schizophrenia bulletin, 1997, Volume: 23, Issue:3 Topics: Attention; Brain Mapping; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interneurons; Mental Recall; Nerve Net; Neurons; Prefrontal Cortex; Psychiatric Status Rating Scales; Pyramidal Cells; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission	1997
Catecholamines in the central nervous system. Overview. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Afferent Pathways; Animals; Attention; Behavior, Animal; Brain; Catecholamines; Dopamine; Glutamic Acid; Humans; Memory; Neurons; Neurotransmitter Agents; Parkinson Disease; Receptors, Adrenergic; Receptors, Dopamine; Schizophrenia	1998
Neurobiology of schizophrenia. Current opinion in neurobiology, 1997, Volume: 7, Issue:5 Topics: Animals; Dopamine; Glutamic Acid; Humans; Phenotype; Schizophrenia	1997
Glutamate in schizophrenia: clinical and research implications. Schizophrenia research, 1997, Oct-30, Volume: 27, Issue:2-3 Topics: Aging; Citric Acid Cycle; Dopamine; Glutamic Acid; Humans; Phencyclidine; Receptors, Amino Acid; Receptors, Glutamate; Schizophrenia	1997
[Biological etiology of schizophrenia]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1997, Volume: 99, Issue:9 Topics: Dopamine; Glutamic Acid; Humans; Neurons; Schizophrenia	1997
Schizophrenia and glutamatergic transmission. Critical reviews in neurobiology, 1998, Volume: 12, Issue:1-2 Topics: Brain Chemistry; Glutamic Acid; Humans; Receptors, Glutamate; Schizophrenia; Synaptic Transmission	1998
Limbic-cortical neuronal damage and the pathophysiology of schizophrenia. Schizophrenia bulletin, 1998, Volume: 24, Issue:2 Topics: Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Drug Resistance; Frontal Lobe; Glutamic Acid; Hippocampus; Humans; Limbic System; Models, Neurological; Neural Pathways; Schizophrenia; Severity of Illness Index	1998
Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophrenia bulletin, 1998, Volume: 24, Issue:2 Topics: Animals; Antipsychotic Agents; Attention; Basal Ganglia; Brain Stem; Disease Models, Animal; Dopamine; Dopamine Agents; Glutamic Acid; Habituation, Psychophysiologic; Humans; Inhibition, Psychological; Limbic System; Mice; Mice, Knockout; Models, Neurological; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Inbred Strains; Reflex, Startle; Schizophrenia	1998
[Glycine therapy of schizophrenia; its rationale and a review of clinical trials]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1998, Volume: 18, Issue:3 Topics: Acetamides; Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cycloserine; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Prodrugs; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine	1998
Nicotine dependence in schizophrenia: clinical phenomena and laboratory findings. The American journal of psychiatry, 1998, Volume: 155, Issue:11 Topics: Adult; Animals; Bungarotoxins; Comorbidity; Dopamine; Drug Interactions; Glutamic Acid; Humans; Ion Channel Gating; Middle Aged; Models, Biological; Models, Neurological; Nicotine; Prevalence; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, Nicotinic; Schizophrenia; Schizophrenic Psychology; Self Medication; Smoking; Tobacco Use Disorder	1998
The glutamate synapse in neuropsychiatric disorders. Focus on schizophrenia and Alzheimer's disease. Progress in brain research, 1998, Volume: 116 Topics: Alzheimer Disease; Animals; Glutamic Acid; Humans; Mental Disorders; Schizophrenia; Synapses	1998
A glutamatergic deficiency model of schizophrenia. The British journal of psychiatry. Supplement, 1999, Issue:37 Topics: Biogenic Monoamines; Cerebral Cortex; Dopamine Antagonists; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia	1999
Cognitive deficit in schizophrenia and its neurochemical basis. The British journal of psychiatry. Supplement, 1999, Issue:37 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; N-Methylaspartate; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology	1999
Glutamatergic aspects of schizophrenia. The British journal of psychiatry. Supplement, 1999, Issue:37 Topics: Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ketamine; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tomography, Emission-Computed	1999
Transmitter dysfunction during the process of schizophrenia. Acta psychiatrica Scandinavica. Supplementum, 1999, Volume: 395 Topics: Animals; Brain; Corpus Striatum; Dopamine; Glutamic Acid; Humans; Limbic System; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Prefrontal Cortex; Repression-Sensitization; Schizophrenia; Sensory Thresholds; Serotonin; Temporal Lobe; Thalamus	1999
Neurochemical brain imaging investigations of schizophrenia. Biological psychiatry, 1999, Sep-01, Volume: 46, Issue:5 Topics: Aspartic Acid; Brain; Corpus Striatum; Dopamine; Glutamic Acid; Homovanillic Acid; Humans; Magnetic Resonance Imaging; Receptors, Dopamine D2; Receptors, GABA; Schizophrenia; Serotonin; Synaptic Transmission; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1999
Neurotransmitter interactions in schizophrenia--therapeutic implications. Biological psychiatry, 1999, Nov-15, Volume: 46, Issue:10 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Glutamic Acid; Humans; Interneurons; Neuroprotective Agents; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin; Thalamus	1999
Cognitive dysfunction in schizophrenia: unifying basic research and clinical aspects. European archives of psychiatry and clinical neuroscience, 1999, Volume: 249 Suppl 4 Topics: Brain; Cognition Disorders; Dopamine; Electroencephalography; Evoked Potentials; Glutamic Acid; Humans; Magnetic Resonance Imaging; Nerve Net; Receptors, N-Methyl-D-Aspartate; Schizophrenia	1999
Proton magnetic resonance spectroscopy of the human brain in schizophrenia. Reviews in the neurosciences, 2000, Volume: 11, Issue:2-3 Topics: Aspartic Acid; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Protons; Schizophrenia	2000
Serotonin model of schizophrenia: emerging role of glutamate mechanisms. Brain research. Brain research reviews, 2000, Volume: 31, Issue:2-3 Topics: Animals; Brain; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, Serotonin; Schizophrenia; Serotonin	2000
[Endogenous D-serine in mammalian brains]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2000, Volume: 20, Issue:1 Topics: Animals; Brain; Glutamic Acid; Glycine; Humans; Racemases and Epimerases; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Spinocerebellar Degenerations; Synaptic Transmission	2000
Amygdalo-entorhinal inputs to the hippocampal formation in relation to schizophrenia. Annals of the New York Academy of Sciences, 2000, Volume: 911 Topics: Afferent Pathways; Amygdala; Animals; Entorhinal Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Schizophrenia	2000
How schizophrenia develops: new evidence and new ideas. The Harvard mental health letter, 2001, Volume: 17, Issue:8 Topics: Cerebral Ventricles; Diagnostic Imaging; Dopamine; Glutamic Acid; Humans; Neurotransmitter Agents; Schizophrenia	2001
Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence. Annual review of pharmacology and toxicology, 2001, Volume: 41 Topics: Animals; Antipsychotic Agents; Biogenic Monoamines; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Schizophrenia	2001
[Glutamatergic neurotransmission in schizophrenics]. Fortschritte der Neurologie-Psychiatrie, 2001, Volume: 69 Suppl 2 Topics: Glutamic Acid; Humans; Schizophrenia; Synaptic Transmission	2001
The changing roles and targets for animal models of schizophrenia. Biological psychiatry, 2001, Dec-01, Volume: 50, Issue:11 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dopamine; Evoked Potentials; Glutamic Acid; Humans; Models, Genetic; Models, Neurological; Neurotensin; Schizophrenia	2001
Glutamatergic mechanisms in schizophrenia. Annual review of pharmacology and toxicology, 2002, Volume: 42 Topics: Animals; Dopamine; Glutamic Acid; Humans; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2002
Glutamatergic-dopaminergic balance in the brain. Its importance in motor disorders and schizophrenia. Arzneimittel-Forschung, 1992, Volume: 42, Issue:2A Topics: Animals; Brain Chemistry; Dopamine; Glutamates; Glutamic Acid; Humans; Parkinson Disease; Schizophrenia	1992
Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. Neuroscience, 1991, Volume: 41, Issue:1 Topics: Afferent Pathways; Animals; Antipsychotic Agents; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Hallucinogens; Homeostasis; Humans; Models, Neurological; Models, Psychological; Neurons; Nucleus Accumbens; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia; Secretory Rate; Stress, Psychological; Synaptic Transmission; Up-Regulation	1991
Glutamate receptor antagonism: neurotoxicity, anti-akinetic effects, and psychosis. Journal of neural transmission. Supplementum, 1991, Volume: 34 Topics: Animals; Glutamates; Glutamic Acid; Humans; Models, Neurological; Models, Psychological; Nerve Degeneration; Neurons; Neurotoxins; Psychotic Disorders; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia	1991
Interactions between glutamatergic and monoaminergic systems within the basal ganglia--implications for schizophrenia and Parkinson's disease. Trends in neurosciences, 1990, Volume: 13, Issue:7 Topics: Animals; Anticonvulsants; Aspartic Acid; Basal Ganglia; Biogenic Amines; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Humans; N-Methylaspartate; Parkinson Disease; Schizophrenia	1990
Schizophrenia: a subcortical neurotransmitter imbalance syndrome? Schizophrenia bulletin, 1990, Volume: 16, Issue:3 Topics: Animals; Arousal; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Humans; Neural Pathways; Receptors, Dopamine; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia; Schizophrenic Psychology	1990
The role of excitatory amino acids in neuropsychiatric illness. The Journal of neuropsychiatry and clinical neurosciences, 1990,Winter, Volume: 2, Issue:1 Topics: Amino Acids; Brain; Glutamates; Glutamic Acid; Humans; Neurocognitive Disorders; Neurons; Receptors, Amino Acid; Receptors, Cell Surface; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission	1990
Postmortem neurochemistry in schizophrenia. The Psychiatric clinics of North America, 1986, Volume: 9, Issue:1 Topics: Acetylcholine; Brain; Brain Chemistry; Cholecystokinin; Dopamine; Endorphins; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neurotensin; Neurotransmitter Agents; Norepinephrine; Peptides; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Dopamine D2; Schizophrenia; Serotonin; Substance P	1986

Trials

17 trial(s) available for glutamic acid and Schizophrenia

Article	Year
N-Acetylcysteine effects on glutathione and glutamate in schizophrenia: A preliminary MRS study. Psychiatry research. Neuroimaging, 2022, Volume: 325 Topics: Acetylcysteine; Glutamic Acid; Glutathione; Humans; Psychotic Disorders; Schizophrenia	2022
Dose-Dependent Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia: A Double-Blind, Placebo-Controlled, Randomized, Target Engagement Clinical Trial of the NMDA Glutamate Receptor Agonist d-serine. Biological psychiatry, 2023, 07-15, Volume: 94, Issue:2 Topics: Antipsychotic Agents; Double-Blind Method; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine	2023
Phase 2 Results Indicate Evenamide, A Selective Modulator of Glutamate Release, Is Associated With Clinically Important Long-Term Efficacy When Added to an Antipsychotic in Patients With Treatment-Resistant Schizophrenia. The international journal of neuropsychopharmacology, 2023, 08-29, Volume: 26, Issue:8 Topics: Antipsychotic Agents; Glutamic Acid; Humans; Schizophrenia; Schizophrenia, Treatment-Resistant	2023
Glutamatergic deficit and schizophrenia-like negative symptoms: new evidence from ketamine-induced mismatch negativity alterations in healthy male humans. Journal of psychiatry & neuroscience : JPN, 2017, Volume: 42, Issue:4 Topics: Adult; Brain; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Glutamic Acid; Healthy Volunteers; Humans; Ketamine; Male; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Single-Blind Method; Young Adult	2017
Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial. JAMA psychiatry, 2018, 01-01, Volume: 75, Issue:1 Topics: Adult; Antipsychotic Agents; Biomarkers; Brain; Drug Development; Female; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance Imaging; Male; Middle Aged; Molecular Targeted Therapy; Neuroimaging; Oxygen; Psychotic Disorders; Receptors, Glutamate; Schizophrenia; Young Adult	2018
Response to initial antipsychotic treatment in first episode psychosis is related to anterior cingulate glutamate levels: a multicentre Molecular psychiatry, 2018, Volume: 23, Issue:11 Topics: Adult; Antipsychotic Agents; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Thalamus; Young Adult	2018
Reduced auditory evoked gamma-band response and schizophrenia-like clinical symptoms under subanesthetic ketamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:7 Topics: Acoustic Stimulation; Adult; Brain; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Gamma Rhythm; Glutamic Acid; Humans; Ketamine; Male; Schizophrenia; Young Adult	2019
Effects of acute N-acetylcysteine challenge on cortical glutathione and glutamate in schizophrenia: A pilot in vivo proton magnetic resonance spectroscopy study. Psychiatry research, 2019, Volume: 275 Topics: Acetylcysteine; Adolescent; Adult; Female; Free Radical Scavengers; Glutamic Acid; Glutathione; Gyrus Cinguli; Humans; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2019
Effect of L-theanine on glutamatergic function in patients with schizophrenia. Acta neuropsychiatrica, 2015, Volume: 27, Issue:5 Topics: Adult; Antipsychotic Agents; Brain; Case-Control Studies; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Sleep; Treatment Outcome	2015
Supplementation of antipsychotic treatment with sarcosine – GlyT1 inhibitor – causes changes of glutamatergic (1)NMR spectroscopy parameters in the left hippocampus in patients with stable schizophrenia. Neuroscience letters, 2015, Oct-08, Volume: 606 Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Double-Blind Method; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Humans; Inositol; Male; Middle Aged; Sarcosine; Schizophrenia; Young Adult	2015
Elevated plasma γ-aminobutyrate/glutamate ratio and responses to risperidone antipsychotic treatment in schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry, 2010, Oct-01, Volume: 34, Issue:7 Topics: Adult; Analysis of Variance; Antipsychotic Agents; Chromatography, Liquid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Risperidone; Schizophrenia; Statistics as Topic; Tandem Mass Spectrometry; Young Adult	2010
Proton magnetic resonance spectroscopy study of brain metabolite changes after antipsychotic treatment. Pharmacopsychiatry, 2011, Volume: 44, Issue:4 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Brain Chemistry; Diagnostic and Statistical Manual of Mental Disorders; Female; Follow-Up Studies; Fourier Analysis; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Schizophrenia; Thalamus; Young Adult	2011
Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 13, Issue:1 Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glutamic Acid; Haloperidol; Humans; Injections, Intravenous; Ketamine; Male; Middle Aged; Psychoses, Substance-Induced; Schizophrenia; Time Factors	1995
Observation of metabolic changes in chronic schizophrenia after neuroleptic treatment by in vivo hydrogen magnetic resonance spectroscopy. Investigative radiology, 1996, Volume: 31, Issue:6 Topics: Adolescent; Adult; Antipsychotic Agents; Chronic Disease; Creatine; Female; Follow-Up Studies; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia	1996
Glutamatergic neurotransmission involves structural and clinical deficits of schizophrenia. Biological psychiatry, 1998, Oct-15, Volume: 44, Issue:8 Topics: Adult; Brain; Brain Chemistry; Glutamic Acid; Humans; Male; Neurotransmitter Agents; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission; Tomography, X-Ray Computed	1998
Cerebrospinal fluid glutamate inversely correlates with positive symptom severity in unmedicated male schizophrenic/schizoaffective patients. Biological psychiatry, 1999, Jan-01, Volume: 45, Issue:1 Topics: Adult; Antipsychotic Agents; Glutamic Acid; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology	1999
Plasma concentrations of amino acids in chronic schizophrenics treated with clozapine. Neuropsychobiology, 2001, Volume: 44, Issue:4 Topics: Adult; Amino Acids; Amino Acids, Neutral; Clozapine; Female; Follow-Up Studies; Glutamic Acid; Humans; Male; Reference Values; Schizophrenia	2001

Other Studies

418 other study(ies) available for glutamic acid and Schizophrenia

Article	Year
Abnormal neurobiochemical metabolites in the first Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021, Oct-28, Volume: 46, Issue:10 Topics: Aspartic Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2021
Magnetic resonance spectroscopic evidence of increased choline in the dorsolateral prefrontal and visual cortices in recent onset schizophrenia. Neuroscience letters, 2022, 01-23, Volume: 770 Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Schizophrenia; Visual Cortex	2022
Rare Pathogenic Variants in Genes Implicated in Glutamatergic Neurotransmission Pathway Segregate with Schizophrenia in Pakistani Families. Genes, 2021, 11-26, Volume: 12, Issue:12 Topics: Adult; Exome; Female; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Glutamic Acid; Humans; Male; Middle Aged; Pakistan; Pedigree; Penetrance; Schizophrenia; Signal Transduction; Synaptic Transmission	2021
The glutamate/N-methyl-d-aspartate receptor (NMDAR) model of schizophrenia at 35: On the path from syndrome to disease. Schizophrenia research, 2022, Volume: 242 Topics: Aspartic Acid; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2022
Altered glutamate level and its association with working memory among patients with treatment-resistant schizophrenia (TRS): a proton magnetic resonance spectroscopy study. Psychological medicine, 2023, Volume: 53, Issue:7 Topics: Adult; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Memory, Short-Term; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenia, Treatment-Resistant	2023
Relating Glutamate, Conditioned, and Clinical Hallucinations via 1H-MR Spectroscopy. Schizophrenia bulletin, 2022, 06-21, Volume: 48, Issue:4 Topics: Glutamic Acid; Hallucinations; Humans; Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2022
Glutamatergic dysfunction is associated with phenotypes of VGF-overexpressing mice. Experimental brain research, 2022, Volume: 240, Issue:7-8 Topics: Animals; Dizocilpine Maleate; Glutamic Acid; Mice; Phenotype; Prefrontal Cortex; Schizophrenia	2022
Anterior cingulate glutamate levels associate with functional activation and connectivity during sensory integration in schizophrenia: a multimodal Psychological medicine, 2023, Volume: 53, Issue:11 Topics: Brain Mapping; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2023
A longitudinal investigation of GABA, glutamate, and glutamine across the insula during antipsychotic treatment of first-episode schizophrenia. Schizophrenia research, 2022, Volume: 248 Topics: Antipsychotic Agents; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Schizophrenia	2022
Postmortem, in silico, and clinical studies focused on perturbations of glutamate neurobiology in schizophrenia. Schizophrenia research, 2022, Volume: 249 Topics: Autopsy; Brain; Glutamic Acid; Humans; Neurobiology; Schizophrenia	2022
Anterior cingulate glutamate metabolites as a predictor of antipsychotic response in first episode psychosis: data from the STRATA collaboration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:3 Topics: Antipsychotic Agents; Glutamic Acid; Gyrus Cinguli; Humans; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2023
Dorsolateral Prefrontal Cortex Glutamate/Gamma-Aminobutyric Acid (GABA) Alterations in Clinical High Risk and First-Episode Schizophrenia: A Preliminary 7-T Magnetic Resonance Spectroscopy Imaging Study. International journal of molecular sciences, 2022, Dec-13, Volume: 23, Issue:24 Topics: Dorsolateral Prefrontal Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Schizophrenia	2022
Identification of rare missense mutations in the glutamate ionotropic receptor AMPA type subunit genes in schizophrenia. Psychiatric genetics, 2023, 02-01, Volume: 33, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Exons; Glutamic Acid; Humans; Mutation, Missense; Schizophrenia	2023
Increased rostral medial frontal GABA+ in early psychosis is obscured by levels of negative affect. Schizophrenia research, 2023, Volume: 252 Topics: Affect; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Psychotic Disorders; Schizophrenia	2023
The Effect of Clozapine and Novel Glutamate Modulator JNJ-46356479 on Nitrosative Stress in a Postnatal Murine Ketamine Model of Schizophrenia. International journal of molecular sciences, 2023, Jan-05, Volume: 24, Issue:2 Topics: Adult; Animals; Clozapine; Glutamic Acid; Humans; Ketamine; Mice; Nitrosative Stress; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2023
Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia. JAMA psychiatry, 2023, 03-01, Volume: 80, Issue:3 Topics: Glutamic Acid; Hippocampus; Humans; Schizophrenia	2023
Opposite Modulation of the NMDA Receptor by Glycine and S-Ketamine and the Effects on Resting State EEG Gamma Activity: New Insights into the Glutamate Hypothesis of Schizophrenia. International journal of molecular sciences, 2023, Jan-18, Volume: 24, Issue:3 Topics: Biomarkers; Electroencephalography; Glutamic Acid; Humans; Ketamine; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2023
Basal glutamate in the hippocampus and the dorsolateral prefrontal cortex in schizophrenia: Relationships to cognitive proficiency investigated with structural equation modelling. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2023, Volume: 24, Issue:8 Topics: Cognition; Dorsolateral Prefrontal Cortex; Glutamic Acid; Hippocampus; Humans; Latent Class Analysis; Magnetic Resonance Imaging; Memory, Short-Term; Prefrontal Cortex; Schizophrenia	2023
Reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels. Psychological medicine, 2023, Volume: 53, Issue:4 Topics: Antipsychotic Agents; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Psychotic Disorders; Reward; Schizophrenia	2023
Non-linear variations in glutamate dynamics during a cognitive task engagement in schizophrenia. Psychiatry research. Neuroimaging, 2023, Volume: 332 Topics: Cognition; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2023
The association between peripheral inflammation, brain glutamate and antipsychotic response in Schizophrenia: Data from the STRATA collaboration. Brain, behavior, and immunity, 2023, Volume: 111 Topics: Antipsychotic Agents; Brain; Encephalitis; Glutamic Acid; Humans; Inflammation; Interleukin-8; Schizophrenia	2023
Treatment resistance NMDA receptor pathway polygenic score is associated with brain glutamate in schizophrenia. Schizophrenia research, 2023, Volume: 260 Topics: Brain; Glutamic Acid; Gyrus Cinguli; Humans; Multifactorial Inheritance; Proton Magnetic Resonance Spectroscopy; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2023
Alteration in NMDAR-related amino acids in first episode psychosis. Synapse (New York, N.Y.), 2019, Volume: 73, Issue:11 Topics: Asparagine; Chromatography, Liquid; Female; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Male; Mass Spectrometry; Proline; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult	2019
Sociality deficits in serine racemase knockout mice. Brain and behavior, 2019, Volume: 9, Issue:10 Topics: Animals; Behavior, Animal; Choice Behavior; Glutamic Acid; Mice; Mice, Knockout; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Vocalization, Animal	2019
Association of Cortical Glutamate and Working Memory Activation in Patients With Schizophrenia: A Multimodal Proton Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study. Biological psychiatry, 2020, 02-01, Volume: 87, Issue:3 Topics: Glutamic Acid; Humans; Magnetic Resonance Imaging; Memory, Short-Term; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2020
Sleep quality is related to brain glutamate and symptom severity in schizophrenia. Journal of psychiatric research, 2020, Volume: 120 Topics: Adult; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Parietal Lobe; Schizophrenia; Severity of Illness Index; Sleep Wake Disorders; Young Adult	2020
Intra-Regional Glu-GABA vs Inter-Regional Glu-Glu Imbalance: A 1H-MRS Study of the Neurochemistry of Auditory Verbal Hallucinations in Schizophrenia. Schizophrenia bulletin, 2020, 04-10, Volume: 46, Issue:3 Topics: Adult; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Hallucinations; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe	2020
The impact of endurance training and table soccer on brain metabolites in schizophrenia. Brain imaging and behavior, 2020, Volume: 14, Issue:2 Topics: Adult; Aspartic Acid; Brain; Cognition; Creatine; Endurance Training; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inpatients; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Schizophrenia; Thalamus	2020
Hippocampal Pathology in Clinical High-Risk Patients and the Onset of Schizophrenia. Biological psychiatry, 2020, 02-01, Volume: 87, Issue:3 Topics: Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Psychotic Disorders; Schizophrenia	2020
Levels of glutamatergic neurometabolites in patients with severe treatment-resistant schizophrenia: a proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:4 Topics: Adult; Antipsychotic Agents; Cross-Sectional Studies; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Severity of Illness Index	2020
Multimodal Magnetic Resonance Imaging as a Compass and Map for Finding Working Memory Relationships in Schizophrenia. Biological psychiatry, 2020, 02-01, Volume: 87, Issue:3 Topics: Glutamic Acid; Humans; Magnetic Resonance Imaging; Memory, Short-Term; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2020
AMPA receptor subunit localization in schizophrenia anterior cingulate cortex. Schizophrenia research, 2022, Volume: 249 Topics: Calcium Channels; Glutamic Acid; Gyrus Cinguli; Humans; Receptors, AMPA; Schizophrenia	2022
Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine. Cells, 2020, 02-11, Volume: 9, Issue:2 Topics: Antipsychotic Agents; Astrocytes; Cell Membrane; Clozapine; Connexin 43; Glutamic Acid; Humans; Myocarditis; Schizophrenia; Serine; Valproic Acid	2020
Excitatory amino acid transporter (EAAT)1 and EAAT2 mRNA levels are altered in the prefrontal cortex of subjects with schizophrenia. Journal of psychiatric research, 2020, Volume: 123 Topics: Amino Acid Transport System X-AG; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Prefrontal Cortex; RNA, Messenger; Schizophrenia	2020
Neurometabolic correlates of 6 and 16 weeks of treatment with risperidone in medication-naive first-episode psychosis patients. Translational psychiatry, 2020, 01-21, Volume: 10, Issue:1 Topics: Antipsychotic Agents; Glutamic Acid; Humans; Psychotic Disorders; Risperidone; Schizophrenia	2020
Glutamatergic neurometabolites and cortical thickness in treatment-resistant schizophrenia: Implications for glutamate-mediated excitotoxicity. Journal of psychiatric research, 2020, Volume: 124 Topics: Antipsychotic Agents; Clozapine; Glutamic Acid; Humans; Magnetic Resonance Imaging; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2020
Early treatment response in first episode psychosis: a 7-T magnetic resonance spectroscopic study of glutathione and glutamate. Molecular psychiatry, 2020, Volume: 25, Issue:8 Topics: Antipsychotic Agents; Female; Glutamic Acid; Glutathione; Gyrus Cinguli; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Prognosis; Psychotic Disorders; Schizophrenia; Time Factors; Young Adult	2020
Glutamate and Dysconnection in the Salience Network: Neurochemical, Effective Connectivity, and Computational Evidence in Schizophrenia. Biological psychiatry, 2020, 08-01, Volume: 88, Issue:3 Topics: Cerebral Cortex; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Schizophrenia	2020
Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic Treatment. Neuropsychobiology, 2021, Volume: 80, Issue:1 Topics: Adult; Antipsychotic Agents; Cognitive Dysfunction; Default Mode Network; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory; Memory, Episodic; Mental Recall; Proton Magnetic Resonance Spectroscopy; Recognition, Psychology; Risperidone; Schizophrenia; Treatment Outcome; Young Adult	2021
Are working memory and glutamate concentrations involved in early-life stress and severity of psychosis? Brain and behavior, 2020, Volume: 10, Issue:6 Topics: Adverse Childhood Experiences; Glutamic Acid; Humans; Magnetic Resonance Imaging; Memory, Short-Term; Prefrontal Cortex; Psychotic Disorders; Schizophrenia	2020
Glutamatergic hypo-function in the left superior and middle temporal gyri in early schizophrenia: a data-driven three-dimensional proton spectroscopic imaging study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:11 Topics: Aspartic Acid; Creatine; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Protons; Schizophrenia	2020
Excitation-inhibition balance and auditory multistable perception are correlated with autistic traits and schizotypy in a non-clinical population. Scientific reports, 2020, 05-18, Volume: 10, Issue:1 Topics: Adolescent; Adult; Auditory Cortex; Auditory Perception; Autism Spectrum Disorder; Child; Female; Glutamic Acid; Glutamine; Humans; Inhibition, Psychological; Male; Schizophrenia; Schizotypal Personality Disorder; Verbal Learning; Young Adult	2020
Calbindin Deficits May Underlie Dissociable Effects of 5-HT Molecular neurobiology, 2020, Volume: 57, Issue:8 Topics: Animals; Behavior, Animal; Calbindins; Cognition; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Phencyclidine; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Schizophrenia; Serotonin	2020
White matter alterations and the conversion to psychosis: A combined diffusion tensor imaging and glutamate Schizophrenia research, 2022, Volume: 249 Topics: Adult; Anisotropy; Brain; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Female; Glutamic Acid; Humans; Male; Psychotic Disorders; Schizophrenia; White Matter; Young Adult	2022
The integrated model of glutamate and dopamine hypothesis for schizophrenia: Prediction and personalized medicine for prevent potential treatment-resistant patients. Medical hypotheses, 2020, Volume: 143 Topics: Dopamine; Glutamic Acid; Humans; Precision Medicine; Psychotic Disorders; Schizophrenia	2020
Metabolomics approach revealed robust changes in amino acid and biogenic amine signatures in patients with schizophrenia in the early course of the disease. Scientific reports, 2020, 08-19, Volume: 10, Issue:1 Topics: Adult; Amino Acids; Antipsychotic Agents; Asparagine; Aspartic Acid; Biogenic Amines; Chromatography, Liquid; Early Diagnosis; Female; Glutamic Acid; Glutamine; Humans; Male; Metabolome; Metabolomics; Proline; Schizophrenia; Tandem Mass Spectrometry; Taurine; Young Adult	2020
The Relationship between the Level of Anterior Cingulate Cortex Metabolites, Brain-Periphery Redox Imbalance, and the Clinical State of Patients with Schizophrenia and Personality Disorders. Biomolecules, 2020, 09-03, Volume: 10, Issue:9 Topics: Adult; Antioxidants; Aspartic Acid; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Personality Disorders; Prognosis; Psychotic Disorders; Schizophrenia; Young Adult	2020
Dopamine and Glutamate in Antipsychotic-Responsive Compared With Antipsychotic-Nonresponsive Psychosis: A Multicenter Positron Emission Tomography and Magnetic Resonance Spectroscopy Study (STRATA). Schizophrenia bulletin, 2021, 03-16, Volume: 47, Issue:2 Topics: Adult; Antipsychotic Agents; Corpus Striatum; Cross-Sectional Studies; Dopamine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult	2021
Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis. Biological psychiatry, 2021, 02-01, Volume: 89, Issue:3 Topics: Antipsychotic Agents; Cognition; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Psychotic Disorders; Schizophrenia	2021
Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities. Cell reports, 2020, 09-15, Volume: 32, Issue:11 Topics: Amino Acid Sequence; Animals; Base Sequence; Behavior, Animal; CRISPR-Cas Systems; Excitatory Postsynaptic Potentials; Female; Gene Deletion; Gene Expression Regulation; Glutamic Acid; Histone-Lysine N-Methyltransferase; Humans; Male; Mice, Inbred ICR; Mutation; Neurodevelopmental Disorders; Prefrontal Cortex; Presynaptic Terminals; Pyramidal Cells; Schizophrenia; Social Behavior; Synapses	2020
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis. Molecular and cellular neurosciences, 2020, Volume: 109 Topics: Adaptor Proteins, Signal Transducing; Cells, Cultured; Clozapine; Dendrites; Drug Evaluation, Preclinical; Fluphenazine; Gene Expression Regulation; Glutamic Acid; Haloperidol; Humans; Induced Pluripotent Stem Cells; Ion Channels; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Oligopeptides; Patch-Clamp Techniques; Protein Isoforms; Schizophrenia; Serine	2020
A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia. Molecular psychiatry, 2021, Volume: 26, Issue:7 Topics: Brain; Cognition; Glutamic Acid; Glutathione; Gyrus Cinguli; Humans; Schizophrenia	2021
Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia. Nature neuroscience, 2020, Volume: 23, Issue:11 Topics: Adult; Cerebral Cortex; Coculture Techniques; Encephalitis; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Interneurons; Male; Microglia; Middle Aged; Mitochondria; Schizophrenia; Young Adult	2020
Glutamate in the Dorsolateral Prefrontal Cortex in Patients With Schizophrenia: A Meta-analysis of Biological psychiatry, 2021, 02-01, Volume: 89, Issue:3 Topics: Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2021
Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity. Stem cells and development, 2020, Volume: 29, Issue:24 Topics: Calcium; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; GABAergic Neurons; Gene Expression Regulation; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Potassium Channels; Protein Subunits; RNA, Messenger; Schizophrenia; Shal Potassium Channels; Spheroids, Cellular; Synapses; Tissue Donors	2020
Reduced GABA/glutamate in the thalamus of individuals at clinical high risk for psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021, Volume: 46, Issue:6 Topics: Adolescent; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Psychotic Disorders; Schizophrenia; Thalamus	2021
Glutamate and Gamma-Aminobutyric Acid Abnormalities in Antipsychotic-Naïve Patients With Schizophrenia: Evidence From Empirical and Meta-analytic Studies Using Magnetic Resonance Spectroscopy. Biological psychiatry, 2021, 02-01, Volume: 89, Issue:3 Topics: Antipsychotic Agents; Cognition; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2021
Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia. Schizophrenia bulletin, 2021, 04-29, Volume: 47, Issue:3 Topics: Adult; Antipsychotic Agents; Caudate Nucleus; Clozapine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Longitudinal Studies; Male; Middle Aged; Outcome Assessment, Health Care; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2021
Effects of JL13, a pyridobenzoxazepine compound, in dopaminergic and glutamatergic models of antipsychotic activity. Behavioural pharmacology, 2021, 02-01, Volume: 32, Issue:1 Topics: Animals; Antipsychotic Agents; Cocaine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Ketamine; Locomotion; Male; Mice; Oxazepines; Piperazines; Pyridines; Reflex, Startle; Schizophrenia	2021
Cannabidiol modulation of hippocampal glutamate in early psychosis. Journal of psychopharmacology (Oxford, England), 2021, Volume: 35, Issue:7 Topics: Adult; Antipsychotic Agents; Cannabidiol; Female; Glutamic Acid; Hippocampus; Humans; Male; Outcome Assessment, Health Care; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Severity of Illness Index; Young Adult	2021
Hyperactivity is a Core Endophenotype of Elevated Neuregulin-1 Signaling in Embryonic Glutamatergic Networks. Schizophrenia bulletin, 2021, 08-21, Volume: 47, Issue:5 Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Embryo, Mammalian; Endophenotypes; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neuregulin-1; Psychomotor Agitation; Receptor, ErbB-4; Schizophrenia; Signal Transduction	2021
Glutamate connectivity associations converge upon the salience network in schizophrenia and healthy controls. Translational psychiatry, 2021, 05-27, Volume: 11, Issue:1 Topics: Brain; Brain Mapping; Glutamic Acid; Humans; Magnetic Resonance Imaging; Nerve Net; Schizophrenia	2021
Reduced cortical GABA and glutamate in high schizotypy. Psychopharmacology, 2021, Volume: 238, Issue:9 Topics: Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Schizophrenia; Schizotypal Personality Disorder	2021
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response. Schizophrenia bulletin, 2022, 01-21, Volume: 48, Issue:1 Topics: Adult; Antipsychotic Agents; Astrocytes; Clozapine; Female; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Male; Middle Aged; Schizophrenia; Serine	2022
MK-801-Treated Oligodendrocytes as a Cellular Model to Study Schizophrenia. Advances in experimental medicine and biology, 2017, Volume: 974 Topics: Cell Fractionation; Cell Line; Chromatography, Liquid; Dizocilpine Maleate; Electronic Data Processing; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hybrid Cells; Nanotechnology; Oligodendroglia; Schizophrenia; Spectrometry, Mass, Electrospray Ionization; Synaptic Transmission; Tandem Mass Spectrometry	2017
Corticolimbic hyper-response to emotion and glutamatergic function in people with high schizotypy: a multimodal fMRI-MRS study. Translational psychiatry, 2017, 04-04, Volume: 7, Issue:4 Topics: Adolescent; Adult; Animals; Brain; Cerebral Cortex; Emotions; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Limbic System; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Models, Animal; Multimodal Imaging; Neuroimaging; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; Schizotypal Personality Disorder; Young Adult	2017
Amygdala activity associated with social choice in mice. Behavioural brain research, 2017, 08-14, Volume: 332 Topics: Amygdala; Animals; Choice Behavior; Electrocorticography; Excitatory Amino Acid Antagonists; Gamma Rhythm; Glutamic Acid; Ketamine; Male; Mice, Inbred C57BL; Psychological Tests; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Social Behavior; Theta Rhythm	2017
Glutamate in dorsolateral prefrontal cortex and auditory verbal hallucinations in patients with schizophrenia: A Progress in neuro-psychopharmacology & biological psychiatry, 2017, 08-01, Volume: 78 Topics: Adult; Case-Control Studies; Female; Glutamic Acid; Glutamine; Hallucinations; Humans; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult	2017
Association between serum levels of glutamate and neurotrophic factors and response to clozapine treatment. Schizophrenia research, 2018, Volume: 192 Topics: Adult; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Glutamic Acid; Humans; Male; Middle Aged; Nerve Growth Factors; Psychiatric Status Rating Scales; Schizophrenia; Statistics, Nonparametric	2018
An examination of the roles of glutamate and sex in latent inhibition: Relevance to the glutamate hypothesis of schizophrenia? Psychiatry research, 2017, Volume: 256 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Inhibition, Psychological; Male; N-Methylaspartate; Rats; Rats, Wistar; Schizophrenia; Schizophrenic Psychology; Sex Characteristics	2017
A Polygenic Risk Score of glutamatergic SNPs associated with schizophrenia predicts attentional behavior and related brain activity in healthy humans. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:9 Topics: Adult; Attention; Brain; Brain Mapping; Factor Analysis, Statistical; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Memory, Short-Term; Multifactorial Inheritance; Neuropsychological Tests; Polymorphism, Single Nucleotide; Schizophrenia; Schizophrenic Psychology; Thinking; White People	2017
Glutamatergic metabolites among adolescents at risk for psychosis. Psychiatry research, 2017, Volume: 257 Topics: Adolescent; Adolescent Behavior; Corpus Striatum; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Neostriatum; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Risk Factors; Schizophrenia	2017
Exome sequencing in schizophrenic patients with high levels of homozygosity identifies novel and extremely rare mutations in the GABA/glutamatergic pathways. PloS one, 2017, Volume: 12, Issue:8 Topics: Adolescent; Adult; Aged; DNA Mutational Analysis; Exome; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Homozygote; Humans; Inbreeding; Male; Middle Aged; Mutation; Schizophrenia; Young Adult	2017
On the brink of precision medicine for psychosis: Treating the patient, not the disease: A commentary on: Association between serum levels of glutamate and neurotrophic factors and response to clozapine treatment by Krivoy et al. 2017. Schizophrenia research, 2018, Volume: 193 Topics: Antipsychotic Agents; Clozapine; Glutamic Acid; Humans; Nerve Growth Factors; Precision Medicine; Psychotic Disorders; Schizophrenia	2018
In Vivo Brain Glycine and Glutamate Concentrations in Patients With First-Episode Psychosis Measured by Echo Time-Averaged Proton Magnetic Resonance Spectroscopy at 4T. Biological psychiatry, 2018, 03-15, Volume: 83, Issue:6 Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Female; Glutamic Acid; Glycine; Humans; Image Processing, Computer-Assisted; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2018
Glutamatergic Response to Heat Pain Stress in Schizophrenia. Schizophrenia bulletin, 2018, 06-06, Volume: 44, Issue:4 Topics: Adult; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hot Temperature; Humans; Male; Middle Aged; Nociceptive Pain; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Stress, Physiological; Young Adult	2018
Mismatch negativity: A simple and useful biomarker of N-methyl-d-aspartate receptor (NMDAR)-type glutamate dysfunction in schizophrenia. Schizophrenia research, 2018, Volume: 191 Topics: Animals; Contingent Negative Variation; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2018
Paving the Way for Targeted Drug Development in Schizophrenia. JAMA psychiatry, 2018, 01-01, Volume: 75, Issue:1 Topics: Biomarkers; Drug Development; Glutamic Acid; Humans; Psychotic Disorders; Schizophrenia	2018
N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse. Addiction biology, 2019, Volume: 24, Issue:1 Topics: Animals; Cocaine; Comorbidity; Dopamine; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Knockout; Microdialysis; Nucleus Accumbens; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Self Stimulation; Serine; Substance-Related Disorders	2019
Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients. Nature communications, 2017, 11-27, Volume: 8, Issue:1 Topics: Adult; Animals; Autoantibodies; Calcium; Ephrin-B2; Female; Glutamic Acid; HEK293 Cells; Hippocampus; Humans; Long-Term Potentiation; Male; Mice; Middle Aged; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Single Molecule Imaging; Synapses; Synaptic Transmission; Young Adult	2017
Evidence for regional hippocampal damage in patients with schizophrenia. Neuroradiology, 2018, Volume: 60, Issue:2 Topics: Adult; Case-Control Studies; Female; Glutamic Acid; Gray Matter; Hippocampus; Humans; Image Interpretation, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Software	2018
Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice. Neural plasticity, 2017, Volume: 2017 Topics: Animals; Behavior, Animal; Cerebral Cortex; Glutamic Acid; Mice; Mice, Knockout; Neurons; Schizophrenia; Synaptic Transmission; Synaptosomal-Associated Protein 25; Syntaxin 1; Vesicle-Associated Membrane Protein 2	2017
Altered Gradients of Glutamate and Gamma-Aminobutyric Acid Transcripts in the Cortical Visuospatial Working Memory Network in Schizophrenia. Biological psychiatry, 2018, 04-15, Volume: 83, Issue:8 Topics: Adult; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Memory, Short-Term; Middle Aged; Nerve Net; Prefrontal Cortex; Schizophrenia; Space Perception; Visual Cortex; Visual Perception	2018
7T Proton Magnetic Resonance Spectroscopy of the Anterior Cingulate Cortex in First-Episode Schizophrenia. Schizophrenia bulletin, 2019, 01-01, Volume: 45, Issue:1 Topics: Adult; Aspartic Acid; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult	2019
Striatal neurometabolite levels in patients with schizophrenia undergoing long-term antipsychotic treatment: A proton magnetic resonance spectroscopy and reliability study. Psychiatry research. Neuroimaging, 2018, 03-30, Volume: 273 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Schizophrenia	2018
Excitatory Amino Acids in Schizophrenia: Both What You Have, and What You Do With Them. Biological psychiatry, 2018, 03-15, Volume: 83, Issue:6 Topics: Brain; Excitatory Amino Acids; Glutamic Acid; Glycine; Humans; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2018
Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study. Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018, Volume: 3, Issue:3 Topics: Adult; Body Temperature; Brain; Female; Glutamic Acid; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2018
Toward Better Strategies for Understanding Disrupted Cortical Excitatory/Inhibitory Balance in Schizophrenia. Biological psychiatry, 2018, 04-15, Volume: 83, Issue:8 Topics: gamma-Aminobutyric Acid; Glutamic Acid; Humans; Memory, Short-Term; Schizophrenia	2018
Effects of cariprazine on extracellular levels of glutamate, GABA, dopamine, noradrenaline and serotonin in the medial prefrontal cortex in the rat phencyclidine model of schizophrenia studied by microdialysis and simultaneous recordings of locomotor acti Psychopharmacology, 2018, Volume: 235, Issue:5 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Locomotion; Male; Microdialysis; Norepinephrine; Phencyclidine; Piperazines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin	2018
THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders. Translational psychiatry, 2018, 04-25, Volume: 8, Issue:1 Topics: Autistic Disorder; Base Sequence; Dronabinol; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Intellectual Disability; Mental Disorders; Mitochondria; Neurons; Post-Synaptic Density; Schizophrenia; Transcriptome	2018
Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:8 Topics: Adult; Female; Glutamic Acid; Gyrus Cinguli; Humans; Kynurenic Acid; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Saliva; Schizophrenia; Stress, Psychological	2018
Lower glutamate level in temporo-parietal junction may predict a better response to tDCS in schizophrenia. Schizophrenia research, 2018, Volume: 201 Topics: Adult; Glutamic Acid; Hallucinations; Humans; Outcome Assessment, Health Care; Parietal Lobe; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe; Transcranial Direct Current Stimulation	2018
Anterior Cingulate Glutamate and GABA Associations on Functional Connectivity in Schizophrenia. Schizophrenia bulletin, 2019, 04-25, Volume: 45, Issue:3 Topics: Adult; Connectome; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe; Young Adult	2019
Glutathione and glutamate in schizophrenia: a 7T MRS study. Molecular psychiatry, 2020, Volume: 25, Issue:4 Topics: Adult; Aspartic Acid; Brain; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2020
Ketogenic diet for schizophrenia: Nutritional approach to antipsychotic treatment. Medical hypotheses, 2018, Volume: 118 Topics: Antipsychotic Agents; Brain; Diet; Diet, Ketogenic; Dietary Fats; Energy Intake; Energy Metabolism; Fasting; Glutamic Acid; Humans; Ketone Bodies; Ketosis; Models, Theoretical; Schizophrenia	2018
Effects of N-acetylcysteine on brain glutamate levels and resting perfusion in schizophrenia. Psychopharmacology, 2018, Volume: 235, Issue:10 Topics: Acetylcysteine; Adult; Brain; Caudate Nucleus; Cerebrovascular Circulation; Creatine; Cross-Over Studies; Double-Blind Method; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Regional Blood Flow; Rest; Schizophrenia	2018
D-Amino Acid Oxidase Inhibition: A New Glutamate Twist for Clozapine Augmentation in Schizophrenia? Biological psychiatry, 2018, 09-15, Volume: 84, Issue:6 Topics: Antipsychotic Agents; Clozapine; Double-Blind Method; Glutamic Acid; Humans; Oxidoreductases; Schizophrenia; Sodium Benzoate	2018
Neurometabolic abnormalities in the associative striatum in antipsychotic-naïve first episode psychosis patients. Psychiatry research. Neuroimaging, 2018, 11-30, Volume: 281 Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Corpus Striatum; Disease Progression; Dopamine; Female; Glutamic Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult	2018
Electrophysiological evidence for abnormal glutamate-GABA association following psychosis onset. Translational psychiatry, 2018, 10-08, Volume: 8, Issue:1 Topics: Acoustic Stimulation; Adult; Brain; Electroencephalography; Evoked Potentials, Auditory; Female; Gamma Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Psychotic Disorders; Schizophrenia; Young Adult	2018
Heritability of cerebral glutamate levels and their association with schizophrenia spectrum disorders: a Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:3 Topics: Adult; Denmark; Female; Genetic Predisposition to Disease; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Registries; Schizophrenia; Thalamus	2019
A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme. Scientific reports, 2018, 10-19, Volume: 8, Issue:1 Topics: Adult; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Homozygote; Humans; Male; Mutant Proteins; Mutation, Missense; Protein Multimerization; Schizophrenia	2018
Glutamatergic Neurometabolite Levels in Patients With Ultra-Treatment-Resistant Schizophrenia: A Cross-Sectional 3T Proton Magnetic Resonance Spectroscopy Study. Biological psychiatry, 2019, 04-01, Volume: 85, Issue:7 Topics: Adult; Antipsychotic Agents; Caudate Nucleus; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2019
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy. Neuropharmacology, 2019, 03-01, Volume: 146 Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Memantine; Motor Activity; Rats; Rats, Wistar; Schizophrenia; Stress, Psychological; Sucrose; Taurine	2019
Functional magnetic resonance spectroscopy in patients with schizophrenia and bipolar affective disorder: Glutamate dynamics in the anterior cingulate cortex during a working memory task. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019, Volume: 29, Issue:2 Topics: Adult; Analysis of Variance; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Schizophrenia; Young Adult	2019
A longitudinal magnetic resonance spectroscopy study investigating effects of risperidone in the anterior cingulate cortex and hippocampus in schizophrenia. Schizophrenia research, 2019, Volume: 210 Topics: Adult; Antipsychotic Agents; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Risperidone; Schizophrenia; Young Adult	2019
Gamma-band auditory steady-state response is associated with plasma levels of d-serine in schizophrenia: An exploratory study. Schizophrenia research, 2019, Volume: 208 Topics: Adolescent; Adult; Case-Control Studies; Electroencephalography; Evoked Potentials, Auditory; Female; GABAergic Neurons; Gamma Rhythm; Glutamic Acid; Glutamine; Glycine; Humans; Male; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Young Adult	2019
Altered glutamatergic response and functional connectivity in treatment resistant schizophrenia: the effect of riluzole and therapeutic implications. Psychopharmacology, 2019, Volume: 236, Issue:7 Topics: Adult; Cerebrovascular Circulation; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Net; Riluzole; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult	2019
Genetic variability of glutamate reuptake: Effect on white matter integrity and working memory in schizophrenia. Schizophrenia research, 2019, Volume: 208 Topics: Adult; Diffusion Tensor Imaging; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Humans; Male; Memory, Short-Term; Middle Aged; Polymorphism, Single Nucleotide; Schizophrenia; Schizophrenic Psychology; White Matter	2019
Elucidating the glutamatergic processes underlying mismatch negativity deficits in early stage bipolar disorder and schizophrenia: A combined Journal of psychiatric research, 2019, Volume: 113 Topics: Adolescent; Adult; Bipolar Disorder; Electroencephalography; Evoked Potentials, Auditory; Female; Glutamic Acid; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2019
Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry, 2019, 12-20, Volume: 95 Topics: Animals; Cannabidiol; Disease Models, Animal; Endocannabinoids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Neurons; Poly I-C; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia; Signal Transduction	2019
Markers of glutamate and GABA neurotransmission in the prefrontal cortex of schizophrenia subjects: Disease effects differ across anatomical levels of resolution. Schizophrenia research, 2020, Volume: 217 Topics: gamma-Aminobutyric Acid; Glutamic Acid; Humans; Prefrontal Cortex; Schizophrenia; Synaptic Transmission	2020
Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain. Psychopharmacology, 2013, Volume: 230, Issue:1 Topics: Animals; Antipsychotic Agents; Astrocytes; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Haloperidol; Homeostasis; Magnetic Resonance Spectroscopy; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Schizophrenia; Time Factors	2013
In vivo neurometabolic profiling to characterize the effects of social isolation and ketamine-induced NMDA antagonism: a rodent study at 7.0 T. Schizophrenia bulletin, 2014, Volume: 40, Issue:3 Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Ketamine; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Social Isolation	2014
Proton magnetic resonance spectroscopy of the substantia nigra in schizophrenia. Schizophrenia research, 2013, Volume: 147, Issue:2-3 Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Protons; Schizophrenia; Substantia Nigra; Young Adult	2013
A new beginning for a broken mind: balancing neuregulin 1 reverses synaptic dysfunction. Neuron, 2013, May-22, Volume: 78, Issue:4 Topics: Animals; Female; Glutamic Acid; Humans; Male; Neuregulin-1; Prosencephalon; Schizophrenia; Synaptic Transmission	2013
Reversal of behavioral deficits and synaptic dysfunction in mice overexpressing neuregulin 1. Neuron, 2013, May-22, Volume: 78, Issue:4 Topics: Age Factors; Animals; Disease Models, Animal; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Neuregulin-1; Neurons; Prosencephalon; Schizophrenia; Synaptic Transmission; Tissue Distribution	2013
Brain metabolite alterations in young adults at familial high risk for schizophrenia using proton magnetic resonance spectroscopy. Schizophrenia research, 2013, Volume: 148, Issue:1-3 Topics: Adolescent; Analysis of Variance; Aspartic Acid; Brain; Cognition Disorders; Family Health; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Young Adult	2013
Glutamatergic dysbalance and oxidative stress in in vivo and in vitro models of psychosis based on chronic NMDA receptor antagonism. PloS one, 2013, Volume: 8, Issue:7 Topics: Animals; Antipsychotic Agents; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Hippocampus; Male; Oxidative Stress; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tyrosine	2013
Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function. Biological psychiatry, 2014, Mar-01, Volume: 75, Issue:5 Topics: Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Dihydroxyphenylalanine; Dopamine; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Positron-Emission Tomography; Protons; Schizophrenia	2014
Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia. Schizophrenia bulletin, 2014, Volume: 40, Issue:5 Topics: Adolescent; Adult; Aspartic Acid; Chronic Disease; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prodromal Symptoms; Psychotic Disorders; Risk; Schizophrenia; Young Adult	2014
Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia. JAMA psychiatry, 2013, Volume: 70, Issue:12 Topics: Adult; Aspartic Acid; Biomarkers; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multimodal Imaging; Schizophrenia; Young Adult	2013
The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice. Molecular and cellular neurosciences, 2014, Volume: 58 Topics: Animals; Carrier Proteins; Cells, Cultured; Dysbindin; Dystrophin-Associated Proteins; Glutamic Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred DBA; Neurons; Receptors, AMPA; Schizophrenia; Synaptic Transmission	2014
Increased glutamine in patients undergoing long-term treatment for schizophrenia: a proton magnetic resonance spectroscopy study at 3 T. JAMA psychiatry, 2014, Volume: 71, Issue:3 Topics: Adult; Choline; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Severity of Illness Index; Time Factors	2014
The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:12 Topics: Animals; Cannabinoids; Cells, Cultured; Cerebral Cortex; CHO Cells; Cricetulus; Glutamic Acid; Male; Mice, Knockout; Nerve Tissue Proteins; Nociception; Psychotic Disorders; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Schizophrenia	2014
Pathway analyses implicate glial cells in schizophrenia. PloS one, 2014, Volume: 9, Issue:2 Topics: Bipolar Disorder; Case-Control Studies; Genetic Predisposition to Disease; Genome-Wide Association Study; Glutamic Acid; Humans; Mitochondria; Neuroglia; Polymorphism, Single Nucleotide; Schizophrenia; Signal Transduction	2014
The problem of spurious correlations between pairs of brain metabolite values measured in the same voxel with magnetic resonance spectroscopy. JAMA psychiatry, 2014, Volume: 71, Issue:3 Topics: Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia	2014
In reply. JAMA psychiatry, 2014, Volume: 71, Issue:3 Topics: Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia	2014
Therapeutics: Negative feedback. Nature, 2014, Apr-03, Volume: 508, Issue:7494 Topics: Affect; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Controlled Clinical Trials as Topic; Electric Stimulation Therapy; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Happiness; Humans; Piperazines; Pleasure; Risperidone; Schizophrenia; Schizophrenic Psychology; Sulfones; Treatment Failure	2014
Aetiology: Searching for schizophrenia's roots. Nature, 2014, Apr-03, Volume: 508, Issue:7494 Topics: Antipsychotic Agents; Clinical Trials as Topic; Dopamine; Drug Discovery; England; Glutamic Acid; Humans; Schizophrenia	2014
Transient inactivation of the ventral hippocampus in neonatal rats impairs the mesolimbic regulation of prefrontal glutamate release in adulthood. Neuropharmacology, 2014, Volume: 84 Topics: Animals; Animals, Newborn; Catheters, Indwelling; Disease Models, Animal; Electrodes, Implanted; Glutamic Acid; Hippocampus; Male; Microelectrodes; N-Methylaspartate; Nucleus Accumbens; Prefrontal Cortex; Rats, Wistar; Schizophrenia; Sodium Channel Blockers; Tetrodotoxin	2014
Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia. NeuroImage. Clinical, 2014, Volume: 4 Topics: Adult; Cognition; Cognition Disorders; Executive Function; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Nerve Net; Neurons; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2014
Abnormalities of the glutamine-glutamate-GABA cycle in the schizophrenia brain. Schizophrenia research, 2014, Volume: 156, Issue:2-3 Topics: Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia	2014
The role of GluN2A and GluN2B subunits on the effects of NMDA receptor antagonists in modeling schizophrenia and treating refractory depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:11 Topics: Animals; Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Phenols; Piperidines; Prefrontal Cortex; Quinoxalines; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin; Stereotyped Behavior	2014
Reduced microglial immunoreactivity for endogenous NMDA receptor agonist quinolinic acid in the hippocampus of schizophrenia patients. Brain, behavior, and immunity, 2014, Volume: 41 Topics: Adult; CA1 Region, Hippocampal; Cell Count; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; HLA-DR Antigens; Humans; Male; Microglia; Middle Aged; Neuroimmunomodulation; Organ Specificity; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2014
Prefrontal glutamate levels differentiate early phase schizophrenia and methamphetamine addiction: a (1)H MRS study at 3Tesla. Schizophrenia research, 2014, Volume: 157, Issue:1-3 Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Glutamic Acid; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Young Adult	2014
Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry, 2015, Volume: 20, Issue:4 Topics: Adolescent; Adult; Animals; Aspartic Acid; Dentate Gyrus; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Middle Aged; Nerve Tissue Proteins; Postmortem Changes; Protons; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction; Young Adult	2015
Hippocampal-parietal dysconnectivity and glutamate abnormalities in unmedicated patients with schizophrenia. Hippocampus, 2014, Volume: 24, Issue:12 Topics: Adult; Brain Mapping; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neural Pathways; Parietal Lobe; Proton Magnetic Resonance Spectroscopy; Rest; Schizophrenia	2014
Biological insights from 108 schizophrenia-associated genetic loci. Nature, 2014, Jul-24, Volume: 511, Issue:7510 Topics: Alleles; Brain; Enhancer Elements, Genetic; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Glutamic Acid; Humans; Immunity; Multifactorial Inheritance; Mutation; Odds Ratio; Polymorphism, Single Nucleotide; Schizophrenia; Synaptic Transmission	2014
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics. ACS chemical biology, 2014, Oct-17, Volume: 9, Issue:10 Topics: Allosteric Regulation; Animals; Calcium; Chromatography, Liquid; Genome-Wide Association Study; Glutamic Acid; HEK293 Cells; Humans; Locomotion; Male; Microsomes, Liver; Molecular Structure; Mutation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schizophrenia; Small Molecule Libraries; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Changes in plasma D-serine, L-serine, and glycine levels in treatment-resistant schizophrenia before and after clozapine treatment. Neuroscience letters, 2014, Oct-17, Volume: 582 Topics: Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Schizophrenia; Serine; Stereoisomerism; Treatment Failure	2014
Neonatal NMDA receptor blockade disrupts spike timing and glutamatergic synapses in fast spiking interneurons in a NMDA receptor hypofunction model of schizophrenia. PloS one, 2014, Volume: 9, Issue:10 Topics: Action Potentials; Animals; Animals, Newborn; Bacterial Proteins; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, Reporter; Glutamic Acid; Injections, Subcutaneous; Interneurons; Kv1.1 Potassium Channel; Luminescent Proteins; Mice; Mice, Transgenic; Neocortex; Parvalbumins; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction; Synapses	2014
GABA and glutamate in schizophrenia: a 7 T ¹H-MRS study. NeuroImage. Clinical, 2014, Volume: 6 Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Intelligence; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult	2014
Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia. Biological psychiatry, 2015, Jun-01, Volume: 77, Issue:11 Topics: Adult; Aged; Analysis of Variance; Animals; Antipsychotic Agents; Auditory Cortex; Case-Control Studies; Dendritic Spines; Female; Gene Expression Regulation; Glutamic Acid; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Macaca mulatta; Male; Middle Aged; Postmortem Changes; Protein Interaction Maps; Schizophrenia; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Young Adult	2015
Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia. Neuropharmacology, 2015, Volume: 90 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention; Brain; Cognition; Dendritic Spines; Diet; Female; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Receptors, Metabotropic Glutamate; Reversal Learning; RNA, Messenger; Schizophrenia	2015
α₄β₂ Nicotinic receptor stimulation of the GABAergic system within the orbitofrontal cortex ameliorates the severe crossmodal object recognition impairment in ketamine-treated rats: implications for cognitive dysfunction in schizophrenia. Neuropharmacology, 2015, Volume: 90 Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Ketamine; Male; Neuropsychological Tests; Prefrontal Cortex; Random Allocation; Rats, Long-Evans; Receptors, Nicotinic; Recognition, Psychology; Schizophrenia; Schizophrenic Psychology	2015
Glutamate as a mediating transmitter for auditory hallucinations in schizophrenia: a (1)H MRS study. Schizophrenia research, 2015, Volume: 161, Issue:2-3 Topics: Analysis of Variance; Brain; Brain Mapping; Female; Glutamic Acid; Hallucinations; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Psychiatric Status Rating Scales; Schizophrenia	2015
Is the vigilance regulation model of affective disorders and ADHD also appropriate for other psychiatric disorders (schizophrenia, autism) and is it associated with glutamate? Medical hypotheses, 2015, Volume: 84, Issue:3 Topics: Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Central Nervous System Stimulants; Glutamic Acid; Humans; Models, Psychological; Mood Disorders; Schizophrenia	2015
Glutamatergic neurometabolites in clozapine-responsive and -resistant schizophrenia. The international journal of neuropsychopharmacology, 2015, Jan-20, Volume: 18, Issue:6 Topics: Adult; Antipsychotic Agents; Biomarkers; Brain; Case-Control Studies; Clozapine; Creatine; Drug Resistance; Drug Therapy, Combination; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult	2015
S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Feb-04, Volume: 35, Issue:5 Topics: Adaptor Proteins, Signal Transducing; Amino Acids; Animals; Anxiety; Bridged Bicyclo Compounds, Heterocyclic; DNA Copy Number Variations; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Guanylate Kinases; Locomotion; Long-Term Potentiation; Male; Maze Learning; Memory, Short-Term; Mice; Neurons; Parvalbumins; Phenotype; Prosencephalon; Receptors, AMPA; Schizophrenia; Sex Factors; Social Behavior; Up-Regulation	2015
Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia. Current molecular medicine, 2015, Volume: 15, Issue:2 Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Neuropsychological Tests; Oxidative Stress; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2015
Prolidase activity and oxidative stress in patients with schizophrenia: a preliminary study. JPMA. The Journal of the Pakistan Medical Association, 2015, Volume: 65, Issue:2 Topics: Adult; Case-Control Studies; Dipeptidases; Female; Glutamic Acid; Humans; Male; Oxidative Stress; Schizophrenia; Synaptic Transmission; Young Adult	2015
Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation. Translational psychiatry, 2015, Apr-14, Volume: 5 Topics: Adult; Age Factors; Anisotropy; Aspartic Acid; Case-Control Studies; Choline; Creatine; Diffusion Tensor Imaging; Female; Frontal Lobe; Glutamic Acid; Humans; Inflammation; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Schizophrenia; White Matter; Young Adult	2015
Possible compensatory mechanisms for glutamatergic disconnection found in the auditory cortex in schizophrenia. Biological psychiatry, 2015, Jun-01, Volume: 77, Issue:11 Topics: Animals; Auditory Cortex; Dendritic Spines; Female; Gene Expression Regulation; Glutamic Acid; Humans; Male; Schizophrenia; Signal Transduction	2015
Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:10 Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Female; Frontal Lobe; Glutamic Acid; Gray Matter; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Risk; Schizophrenia; Young Adult	2015
Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:3 Topics: Animals; Antipsychotic Agents; Arrestins; beta-Arrestins; Catalepsy; Disease Models, Animal; Dopamine Agents; Drug Evaluation, Preclinical; Female; Glutamic Acid; Male; Mice, 129 Strain; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Phencyclidine; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Social Behavior	2016
Glutamatergic metabolite correlations with neuropsychological tests in first episode schizophrenia. Psychiatry research, 2015, Aug-30, Volume: 233, Issue:2 Topics: Adolescent; Adult; Female; Follow-Up Studies; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Schizophrenia; Schizophrenic Psychology; Social Adjustment; Statistics as Topic; Thalamus; Young Adult	2015
Glutamatergic dysfunction linked to energy and membrane lipid metabolism in frontal and anterior cingulate cortices of never treated first-episode schizophrenia patients. Schizophrenia research, 2015, Volume: 168, Issue:1-2 Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Membrane Lipids; Phospholipids; Phosphorus Isotopes; Protons; Psychiatric Status Rating Scales; Schizophrenia; Young Adult	2015
Apoptotic markers in cultured fibroblasts correlate with brain metabolites and regional brain volume in antipsychotic-naive first-episode schizophrenia and healthy controls. Translational psychiatry, 2015, Aug-25, Volume: 5 Topics: Adult; Apoptosis; Brain; Caspase 3; Cell Culture Techniques; Female; Fibroblasts; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Male; Organ Size; Schizophrenia; Young Adult	2015
Elevated Myo-Inositol, Choline, and Glutamate Levels in the Associative Striatum of Antipsychotic-Naive Patients With First-Episode Psychosis: A Proton Magnetic Resonance Spectroscopy Study With Implications for Glial Dysfunction. Schizophrenia bulletin, 2016, Volume: 42, Issue:2 Topics: Adult; Aspartic Acid; Choline; Corpus Striatum; Glutamic Acid; Glutamine; Humans; Inositol; Neuroglia; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2016
Cross-sectional Study of Glutamate in the Anterior Cingulate and Hippocampus in Schizophrenia. Schizophrenia bulletin, 2016, Volume: 42, Issue:2 Topics: Adult; Cross-Sectional Studies; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Severity of Illness Index	2016
Cortico-Striatal GABAergic and Glutamatergic Dysregulations in Subjects at Ultra-High Risk for Psychosis Investigated with Proton Magnetic Resonance Spectroscopy. The international journal of neuropsychopharmacology, 2015, Sep-12, Volume: 19, Issue:3 Topics: Corpus Striatum; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Humans; Interview, Psychological; Linear Models; Male; Prefrontal Cortex; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Risk; Schizophrenia; Young Adult	2015
Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons? Molecular psychiatry, 2016, Volume: 21, Issue:6 Topics: Aged; Amino Acid Transport System X-AG; Animals; Astrocytes; Carrier Proteins; Female; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Mediodorsal Thalamic Nucleus; Mice; Middle Aged; Neurons; RNA, Messenger; Schizophrenia; Thalamus	2016
Decreased mRNA expression for the two subunits of system xc(-), SLC3A2 and SLC7A11, in WBC in patients with schizophrenia: Evidence in support of the hypo-glutamatergic hypothesis of schizophrenia. Journal of psychiatric research, 2016, Volume: 72 Topics: Adolescent; Adult; Amino Acid Transport System y+; Antipsychotic Agents; Area Under Curve; Female; Fusion Regulatory Protein 1, Heavy Chain; Glutamic Acid; Humans; Leukocytes; Male; Middle Aged; RNA, Messenger; ROC Curve; Schizophrenia; Sensitivity and Specificity; Young Adult	2016
Substantial DNA methylation differences between two major neuronal subtypes in human brain. Nucleic acids research, 2016, Apr-07, Volume: 44, Issue:6 Topics: Adult; Autopsy; Brain Mapping; CpG Islands; DNA Methylation; Epigenesis, Genetic; GABAergic Neurons; Genetic Loci; Glutamic Acid; Humans; Male; Microtomy; Middle Aged; Neurons; Organ Specificity; Prefrontal Cortex; Risk Factors; Schizophrenia	2016
Treatment-Resistant Schizophrenia Patients Show Elevated Anterior Cingulate Cortex Glutamate Compared to Treatment-Responsive. Schizophrenia bulletin, 2016, Volume: 42, Issue:3 Topics: Adult; Antipsychotic Agents; Chronic Disease; Drug Resistance; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia	2016
Higher serum concentrations of tyrosine and glutamate in schizophrenia patients treated with clozapine, compared to in those treated with conventional antipsychotics. Neuro endocrinology letters, 2015, Volume: 36, Issue:5 Topics: Adult; Amino Acids; Antipsychotic Agents; Chromatography, Ion Exchange; Clopenthixol; Clozapine; Cohort Studies; Female; Glutamic Acid; Haloperidol; Humans; Insulin Resistance; Male; Middle Aged; Perphenazine; Prospective Studies; Psychotic Disorders; Schizophrenia; Thioridazine; Tyrosine	2015
A combined diffusion tensor imaging and magnetic resonance spectroscopy study of patients with schizophrenia. Schizophrenia research, 2016, Volume: 170, Issue:2-3 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Creatine; Diffusion Tensor Imaging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Multimodal Imaging; Myelin Sheath; Psychotic Disorders; Schizophrenia; White Matter	2016
Frontal Glutamate and γ-Aminobutyric Acid Levels and Their Associations With Mismatch Negativity and Digit Sequencing Task Performance in Schizophrenia. JAMA psychiatry, 2016, Volume: 73, Issue:2 Topics: Adult; Auditory Cortex; Auditory Perception; Electroencephalography; Evoked Potentials; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Psychomotor Performance; Schizophrenia; Young Adult	2016
Multiprobe molecular imaging of an NMDA receptor hypofunction rat model for glutamatergic dysfunction. Psychiatry research. Neuroimaging, 2016, Feb-28, Volume: 248 Topics: Animals; Brain; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenine; Male; Molecular Imaging; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tryptophan	2016
An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors. Journal of biomolecular screening, 2016, Volume: 21, Issue:5 Topics: Allosteric Regulation; Alzheimer Disease; Calcium; Drug Discovery; Glutamic Acid; HEK293 Cells; High-Throughput Screening Assays; Humans; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Small Molecule Libraries	2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla. Schizophrenia research, 2016, Volume: 172, Issue:1-3 Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia	2016
Tryptophan Metabolism and White Matter Integrity in Schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:10 Topics: Adult; Analysis of Variance; Anisotropy; Diffusion Tensor Imaging; Female; Glutamic Acid; Humans; Kynurenine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan; White Matter; Young Adult	2016
A heuristic model for working memory deficit in schizophrenia. Biochimica et biophysica acta, 2016, Volume: 1860, Issue:11 Pt B Topics: Brain; Computer Simulation; gamma-Aminobutyric Acid; Glutamic Acid; Heuristics; Humans; Ketamine; Memory Disorders; Memory, Short-Term; Models, Biological; Neurons; Neurotransmitter Agents; Schizophrenia	2016
Targeting glutamate to treat schizophrenia: lessons from recent clinical studies. Psychopharmacology, 2016, Volume: 233, Issue:13 Topics: Antipsychotic Agents; Glutamic Acid; Humans; Schizophrenia	2016
Nature of Glutamate Alterations in Schizophrenia: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies. JAMA psychiatry, 2016, 07-01, Volume: 73, Issue:7 Topics: Brain; Brain Mapping; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Reference Values; Risk Factors; Schizophrenia; Synaptic Transmission	2016
Glutamatergic Dysfunction in Schizophrenia Evaluated With Magnetic Resonance Spectroscopy. JAMA psychiatry, 2016, 07-01, Volume: 73, Issue:7 Topics: Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Schizophrenia	2016
7T Proton Magnetic Resonance Spectroscopy of Gamma-Aminobutyric Acid, Glutamate, and Glutamine Reveals Altered Concentrations in Patients With Schizophrenia and Healthy Siblings. Biological psychiatry, 2017, 03-15, Volume: 81, Issue:6 Topics: Adult; Brain; Female; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Siblings	2017
Down-Regulation of Hippocampal Genes Regulating Dopaminergic, GABAergic, and Glutamatergic Function Following Combined Neonatal Phencyclidine and Post-Weaning Social Isolation of Rats as a Neurodevelopmental Model for Schizophrenia. The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:11 Topics: Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; GABAergic Neurons; Gene Expression Profiling; Gene Expression Regulation; Genetic Predisposition to Disease; Glutamic Acid; Hippocampus; Lamotrigine; Locomotion; Male; Oligonucleotide Array Sequence Analysis; Phencyclidine; Phenotype; Prepulse Inhibition; Rats, Inbred Strains; Recognition, Psychology; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Social Isolation; Sodium Channel Blockers; Synaptic Transmission; Time Factors; Triazines; Weaning	2016
(1)H-MRS and MEGA-PRESS pulse sequence in the study of balance of inhibitory and excitatory neurotransmitters in the human brain of ultra-high risk of schizophrenia patients. Doklady. Biochemistry and biophysics, 2016, Volume: 468, Issue:1 Topics: Adolescent; Adult; Creatine; Frontal Lobe; Functional Laterality; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Male; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Risk; Schizophrenia; Young Adult	2016
Altered brain arginine metabolism in schizophrenia. Translational psychiatry, 2016, 08-16, Volume: 6 Topics: Agmatine; Arginase; Arginine; Autopsy; Blotting, Western; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citrulline; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide Synthase Type III; Ornithine; Regression Analysis; Schizophrenia	2016
Protein Markers of Neurotransmitter Synthesis and Release in Postmortem Schizophrenia Substantia Nigra. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:2 Topics: Dopamine; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2	2017
Glutamatergic and Neuronal Dysfunction in Gray and White Matter: A Spectroscopic Imaging Study in a Large Schizophrenia Sample. Schizophrenia bulletin, 2017, 05-01, Volume: 43, Issue:3 Topics: Adolescent; Adult; Aged; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult	2017
Altered Glutamate and Regional Cerebral Blood Flow Levels in Schizophrenia: A Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:2 Topics: Adolescent; Adult; Aging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenic Psychology; White Matter; Young Adult	2017
Reduced Neural plasticity, 2016, Volume: 2016 Topics: Adolescent; Adult; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Risk; Schizophrenia; Young Adult	2016
The Glutamate Model of Schizophrenia: It's All About Signal Muscarinic Connections. The Journal of pharmacology and experimental therapeutics, 2017, Volume: 360, Issue:2 Topics: Allosteric Regulation; Animals; Disease Models, Animal; Glutamic Acid; Mice; Receptors, Muscarinic; Schizophrenia; Signal Transduction	2017
Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America, 2017, 01-31, Volume: 114, Issue:5 Topics: Animals; Animals, Newborn; Cognition Disorders; Dentate Gyrus; Disease Models, Animal; Electroporation; Excitatory Postsynaptic Potentials; Fear; Genes, Reporter; Glutamic Acid; HEK293 Cells; Humans; Male; Maze Learning; Mice; Mice, Knockout; Neurons; Post-Synaptic Density; Receptors, AMPA; RNA Interference; RNA, Small Interfering; Schizophrenia; Sensory Gating; Synaptic Transmission; Vesicular Transport Proteins	2017
Glutamate imaging (GluCEST) reveals lower brain GluCEST contrast in patients on the psychosis spectrum. Molecular psychiatry, 2017, Volume: 22, Issue:9 Topics: Adolescent; Brain; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Psychotic Disorders; Risk Factors; Schizophrenia	2017
Trans-generation enrichment of clozapine-responsiveness trait in mice using a subchronic hypo-glutamatergic model of schizophrenia:A preliminary study. Behavioural brain research, 2017, 04-14, Volume: 323 Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Female; Frontal Lobe; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Phencyclidine; Schizophrenia; Selective Breeding; Social Behavior	2017
Nardostachys jatamansi Targets BDNF-TrkB to Alleviate Ketamine-Induced Schizophrenia-Like Symptoms in Rats. Neuropsychobiology, 2016, Volume: 74, Issue:2 Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopamine; Glutamic Acid; Ketamine; Male; Nardostachys; Phytotherapy; Plant Extracts; Plant Roots; Rats; Receptor, trkB; Schizophrenia	2016
Differential synaptic changes in the striatum of subjects with undifferentiated versus paranoid schizophrenia. Synapse (New York, N.Y.), 2008, Volume: 62, Issue:8 Topics: Adult; Aged; Calbindins; Corpus Striatum; Dendritic Spines; Female; Glutamic Acid; Humans; Male; Microscopy, Immunoelectron; Middle Aged; Neural Inhibition; Neuropil; Presynaptic Terminals; S100 Calcium Binding Protein G; Schizophrenia; Schizophrenia, Paranoid; Synapses	2008
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania. Biological psychiatry, 2008, Oct-15, Volume: 64, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult	2008
Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophrenia. Journal of chemical neuroanatomy, 2008, Volume: 36, Issue:2 Topics: Amygdala; Animals; Cerebral Cortex; Dentate Gyrus; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Limbic System; Muscarinic Antagonists; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptor Aggregation; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Time Factors	2008
Proton MRS in twin pairs discordant for schizophrenia. Molecular psychiatry, 2010, Volume: 15, Issue:3 Topics: Aspartic Acid; Creatine; Female; Glutamic Acid; Glycerylphosphorylcholine; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex; Protons; Schizophrenia; Twins, Dizygotic; Twins, Monozygotic	2010
Induction of the kynurenine pathway by neurotropic influenza A virus infection. Journal of neuroscience research, 2008, Volume: 86, Issue:16 Topics: Animals; Brain; Cells, Cultured; Chemotaxis, Leukocyte; Coculture Techniques; Encephalitis, Viral; Glutamic Acid; Influenza A virus; Kynurenic Acid; Mice; Mice, Inbred C57BL; Neurons; Orthomyxoviridae Infections; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin; T-Lymphocytes	2008
Implication of neuronal Ca2+ -sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia. Neurobiology of disease, 2008, Volume: 32, Issue:1 Topics: Animals; Calcium; Cells, Cultured; Dentate Gyrus; Female; Glutamic Acid; Hippocampus; Humans; Interneurons; Intracellular Calcium-Sensing Proteins; Ketamine; Male; Neurocalcin; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Nicotinic; Schizophrenia	2008
Aripiprazole and its human metabolite OPC14857 reduce, through a presynaptic mechanism, glutamate release in rat prefrontal cortex: possible relevance to neuroprotective interventions in schizophrenia. Synapse (New York, N.Y.), 2008, Volume: 62, Issue:11 Topics: Animals; Aripiprazole; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Male; Neuroprotective Agents; Piperazines; Prefrontal Cortex; Presynaptic Terminals; Quinolones; Rats; Rats, Sprague-Dawley; Schizophrenia	2008
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia. The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Pressure Liquid; Dopamine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Immunity; Interferon Inducers; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Schizophrenia; Serotonin; Taurine	2009
British Association for Psychopharmacology--2008 Summer Meeting. IDrugs : the investigational drugs journal, 2008, Volume: 11, Issue:10 Topics: Animals; Antipsychotic Agents; Cognition; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Psychopharmacology; Schizophrenia; Schizophrenic Psychology; Serotonin; Serotonin Agents; Substance-Related Disorders	2008
Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia. The International journal of neuroscience, 2008, Volume: 118, Issue:11 Topics: Adolescent; Adult; Aged; Corpus Striatum; Dopamine; Female; Gene Expression Regulation; Glutamic Acid; Humans; Male; Mesencephalon; Middle Aged; Neural Pathways; Prefrontal Cortex; Receptors, Metabotropic Glutamate; RNA, Messenger; Schizophrenia; Substantia Nigra; Ventral Tegmental Area; Young Adult	2008
Investigation of G72 (DAOA) expression in the human brain. BMC psychiatry, 2008, Dec-11, Volume: 8 Topics: Bipolar Disorder; Brain; Carrier Proteins; Cell Line; Chromosome Mapping; Chromosomes, Human, Pair 13; D-Amino-Acid Oxidase; Enzyme Activation; Genetic Predisposition to Disease; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Molecular Probe Techniques; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Interaction Domains and Motifs; RNA, Messenger; Schizophrenia	2008
Metabolite changes and gender differences in schizophrenia using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS). Schizophrenia research, 2009, Volume: 108, Issue:1-3 Topics: Adult; Analysis of Variance; Aspartic Acid; Basal Ganglia; Choline; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Schizophrenia; Sex Characteristics; Young Adult	2009
Neural basis of psychosis-related behaviour in the infection model of schizophrenia. Behavioural brain research, 2009, Dec-07, Volume: 204, Issue:2 Topics: Animals; Avoidance Learning; Brain; Disease Models, Animal; Dopamine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Neurons; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Psychotic Disorders; Rats; Schizophrenia; Schizophrenic Psychology; Sensory Gating; Serotonin	2009
Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Feb-18, Volume: 29, Issue:7 Topics: Aging; Amygdala; Animals; Antipsychotic Agents; Behavior, Animal; Cell Differentiation; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamic Acid; Hippocampus; Male; Mice; Mice, Knockout; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Schizophrenia; Sensory Gating; Synaptic Transmission; Vesicular Glutamate Transport Protein 2	2009
Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8 Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Shape; Dendrites; Epigenesis, Genetic; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Interneurons; Lysine; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Staining and Labeling; Synaptic Transmission	2009
Dopamine-glutamate abnormalities in the frontal cortex associated with the catechol-O-methyltransferase (COMT) in schizophrenia. Brain research, 2009, May-07, Volume: 1269 Topics: Biological Specimen Banks; Catechol O-Methyltransferase; Cell Communication; Dopamine; Female; Frontal Lobe; Glutamic Acid; Humans; Immunohistochemistry; Male; Middle Aged; Neuroglia; Neurons; Paraffin Embedding; Schizophrenia; Time Factors	2009
Effects of theta burst stimulation on glutamate levels in a patient with negative symptoms of schizophrenia. Schizophrenia research, 2009, Volume: 111, Issue:1-3 Topics: Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Transcranial Magnetic Stimulation	2009
Prepulse inhibition and genetic mouse models of schizophrenia. Behavioural brain research, 2009, Dec-07, Volume: 204, Issue:2 Topics: Animals; Brain; Disease Models, Animal; Environment; Genetic Predisposition to Disease; Glutamic Acid; Glycine; Mice; Mice, Transgenic; Nerve Net; Phenotype; Schizophrenia; Sensory Gating	2009
Neurophysiological and neurochemical animal models of schizophrenia: focus on glutamate. Behavioural brain research, 2009, Dec-07, Volume: 204, Issue:2 Topics: Acoustic Stimulation; Amphetamine; Animals; Brain; Disease Models, Animal; Dopamine; Electroencephalography; Evoked Potentials, Auditory; Glutamic Acid; Haplorhini; Humans; Microdialysis; N-Methylaspartate; Rats; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission	2009
Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood. Neuroscience research, 2009, Volume: 64, Issue:3 Topics: Animals; Animals, Newborn; Anxiety; Brain; Disease Models, Animal; Female; Gene Expression; Glutamic Acid; Humans; Memory; Mice; Motor Activity; Polynucleotides; Pregnancy; Prenatal Exposure Delayed Effects; Schizophrenia; Sensory Gating; Social Behavior	2009
Neural circuitry models of schizophrenia: is it dopamine, GABA, glutamate, or something else? Biological psychiatry, 2009, Jun-15, Volume: 65, Issue:12 Topics: Brain; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Pathways; Neurons; Schizophrenia	2009
The glutamate hypothesis for schizophrenia. Early studies produced mixed results, but new approaches are promising. The Harvard mental health letter, 2009, Volume: 25, Issue:11 Topics: Drug Delivery Systems; Glutamic Acid; Humans; Schizophrenia	2009
Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia. Genes, brain, and behavior, 2009, Volume: 8, Issue:7 Topics: Animals; Anxiety; Auditory Diseases, Central; Behavior, Animal; Brain; Brain Chemistry; Disease Models, Animal; Evoked Potentials; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Inhibition; Perceptual Disorders; Phenotype; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Social Behavior; Visual Pathways	2009
MR spectroscopic evaluation of N-acetylaspartate's T2 relaxation time and concentration corroborates white matter abnormalities in schizophrenia. NeuroImage, 2009, Nov-15, Volume: 48, Issue:3 Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Dipeptides; Female; Frontal Lobe; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Phosphocreatine; Protons; Schizophrenia; Water	2009
Decreased glutathione levels and antioxidant enzyme activities in untreated and treated schizophrenic patients. Progress in neuro-psychopharmacology & biological psychiatry, 2009, Oct-01, Volume: 33, Issue:7 Topics: Adolescent; Adult; Analysis of Variance; Antioxidants; Antipsychotic Agents; Case-Control Studies; Catalase; Female; Glutamic Acid; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Humans; Male; Middle Aged; Schizophrenia; Spectrophotometry; Superoxide Dismutase; Young Adult	2009
PIP5K2A-dependent regulation of excitatory amino acid transporter EAAT3. Psychopharmacology, 2009, Volume: 206, Issue:3 Topics: Animals; Blotting, Western; Cell Line; Cell Membrane; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Humans; Kidney; Microscopy, Confocal; Mutation; Oocytes; Patch-Clamp Techniques; Phosphotransferases (Alcohol Group Acceptor); Schizophrenia; Xenopus	2009
The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex. Journal of molecular neuroscience : MN, 2010, Volume: 40, Issue:1-2 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Cholinesterase Inhibitors; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Fluid; Galantamine; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Microdialysis; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Schizophrenia	2010
Cortical development and glutamatergic dysregulation in schizophrenia. Biological psychiatry, 2009, Sep-15, Volume: 66, Issue:6 Topics: Cerebral Cortex; Glutamic Acid; Humans; Schizophrenia	2009
Striatal metabolic alterations in non-psychotic adolescent offspring at risk for schizophrenia: a (1)H spectroscopy study. Schizophrenia research, 2009, Volume: 115, Issue:1 Topics: Adolescent; Aspartic Acid; Chi-Square Distribution; Child; Cohort Studies; Corpus Striatum; Creatine; Energy Metabolism; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Psychiatric Status Rating Scales; Schizophrenia; Sex Factors; Siblings; Young Adult	2009
How high-resolution basal-state functional imaging can guide the development of new pharmacotherapies for schizophrenia. Schizophrenia bulletin, 2009, Volume: 35, Issue:6 Topics: Animals; Blood Volume; CA1 Region, Hippocampal; Cerebrovascular Circulation; Disease Models, Animal; Drug Discovery; Glutamic Acid; Glutaminase; Humans; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Nerve Net; Psychotropic Drugs; Receptors, Glutamate; Schizophrenia; Synaptic Transmission	2009
1H-MRS at 4 tesla in minimally treated early schizophrenia. Molecular psychiatry, 2010, Volume: 15, Issue:6 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Female; Frontal Lobe; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Protons; Schizophrenia; Thalamus; Time Factors	2010
Mutant mouse models: genotype-phenotype relationships to negative symptoms in schizophrenia. Schizophrenia bulletin, 2010, Volume: 36, Issue:2 Topics: Affective Symptoms; Animals; Brain; Disease Models, Animal; DNA Mutational Analysis; Dopamine; Genetic Association Studies; Genotype; Glutamic Acid; Humans; Mice; Mice, Mutant Strains; Motivation; Phenotype; Schizophrenia; Schizophrenic Psychology; Social Behavior	2010
The novel neurotensin analog NT69L blocks phencyclidine (PCP)-induced increases in locomotor activity and PCP-induced increases in monoamine and amino acids levels in the medial prefrontal cortex. Brain research, 2010, Jan-22, Volume: 1311 Topics: Amino Acids; Animals; Antipsychotic Agents; Biogenic Monoamines; Central Nervous System Agents; Disease Models, Animal; Dopamine; Extracellular Space; Glutamic Acid; Glycine; Male; Motor Activity; Neurotensin; Norepinephrine; Peptide Fragments; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin	2010
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis. Science (New York, N.Y.), 2009, Nov-20, Volume: 326, Issue:5956 Topics: Animals; Calcium; Calcium Channels; Carrier Proteins; Drosophila melanogaster; Drosophila Proteins; Dysbindin; Dystrophin-Associated Proteins; Genes, Insect; Glutamic Acid; Homeostasis; Humans; Mutation; Neuromuscular Junction; Neuronal Plasticity; Schizophrenia; Synapses; Synaptic Transmission; Synaptic Vesicles; Transgenes	2009
Testing the glutamate hypothesis of schizophrenia. Nature neuroscience, 2010, Volume: 13, Issue:1 Topics: Animals; Disease Models, Animal; Glutamic Acid; Humans; Interneurons; Mice; Models, Biological; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2010
Effects of atypical (risperidone) and typical (haloperidol) antipsychotic agents on astroglial functions. European archives of psychiatry and clinical neuroscience, 2010, Volume: 260, Issue:6 Topics: Animals; Antipsychotic Agents; Astrocytes; Brain Chemistry; Cell Line; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Haloperidol; Humans; Reactive Oxygen Species; Risperidone; Schizophrenia	2010
Schizophrenia-related endophenotypes in heterozygous neuregulin-1 'knockout' mice. The European journal of neuroscience, 2010, Volume: 31, Issue:2 Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuregulin-1; Phencyclidine; Phenotype; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Sex Factors; Social Behavior	2010
Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder. Biological psychiatry, 2010, Jun-01, Volume: 67, Issue:11 Topics: Adult; Aged; Analysis of Variance; Bipolar Disorder; Female; Functional Laterality; Genotype; Glutamic Acid; Glycoproteins; GPI-Linked Proteins; Gyrus Cinguli; Humans; In Situ Hybridization; Male; Middle Aged; Nerve Tissue Proteins; Netrins; Neuronal Plasticity; Neurons; Presynaptic Terminals; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Synaptic Transmission; Vesicular Glutamate Transport Protein 1	2010
Effect of amphetamine on extracellular concentrations of amino acids in striatum in neurotensin subtype 1 and 2 receptor null mice: a possible interaction between neurotensin receptors and amino acid systems for study of schizophrenia. Neuropharmacology, 2010, Volume: 58, Issue:7 Topics: Amino Acids; Amphetamine; Animals; Central Nervous System Stimulants; Corpus Striatum; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Receptors, Neurotensin; Schizophrenia; Serine	2010
Computational modeling of synaptic neurotransmission as a tool for assessing dopamine hypotheses of schizophrenia. Pharmacopsychiatry, 2010, Volume: 43 Suppl 1 Topics: Animals; Computer Simulation; Corpus Striatum; Dopamine; Glutamic Acid; Humans; Models, Neurological; Presynaptic Terminals; Reproducibility of Results; Schizophrenia; Synaptic Transmission	2010
Thalamic neurochemical abnormalities in individuals with prodromal symptoms of schizophrenia - relationship to auditory event-related potentials. Psychiatry research, 2010, Aug-30, Volume: 183, Issue:2 Topics: Acoustic Stimulation; Adult; Aspartic Acid; Electroencephalography; Evoked Potentials, Auditory; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Neurochemistry; Protons; Radionuclide Imaging; Schizophrenia; Thalamus; Young Adult	2010
Similarities in the behavior and molecular deficits in the frontal cortex between the neurotensin receptor subtype 1 knockout mice and chronic phencyclidine-treated mice: relevance to schizophrenia. Neurobiology of disease, 2010, Volume: 40, Issue:2 Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Down-Regulation; Glutamic Acid; Immobility Response, Tonic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phencyclidine; Polymerase Chain Reaction; Prefrontal Cortex; Receptors, Neurotensin; RNA, Messenger; Schizophrenia; Schizophrenic Psychology; Swimming; Up-Regulation	2010
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Schizophrenia research, 2010, Volume: 122, Issue:1-3 Topics: Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Glutamic Acid; Humans; Schizophrenia; Signal Transduction	2010
Editorial: Etiological hypotheses of mental disorders at the molecular level. The Israel journal of psychiatry and related sciences, 2010, Volume: 47, Issue:1 Topics: Bipolar Disorder; Circadian Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mental Disorders; Receptors, N-Methyl-D-Aspartate; Risk Factors; Schizophrenia; Sleep	2010
D2 and D4 dopamine receptor mRNA distribution in pyramidal neurons and GABAergic subpopulations in monkey prefrontal cortex: implications for schizophrenia treatment. Neuroscience, 2010, Nov-10, Volume: 170, Issue:4 Topics: Animals; Calbindins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; In Situ Hybridization; Interneurons; Macaca fascicularis; Parvalbumins; Prefrontal Cortex; Pyramidal Cells; Receptors, Dopamine D2; Receptors, Dopamine D4; RNA, Messenger; S100 Calcium Binding Protein G; Schizophrenia	2010
Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:12 Topics: Animals; Behavior, Animal; Central Nervous System Viral Diseases; Disease Models, Animal; Dopamine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Mice, Inbred C57BL; Poly I-C; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Schizophrenia; Schizophrenic Psychology; Sex Characteristics	2010
A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression. Neuroscience research, 2011, Volume: 69, Issue:2 Topics: Age of Onset; Animals; Astrocytes; Blotting, Western; Chromatography, High Pressure Liquid; Chromosomes, Human, Pair 9; Female; Gene Expression; Gene Knockdown Techniques; Glutamic Acid; Humans; Male; Middle Aged; Pedigree; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Serine; Transaminases; Translocation, Genetic; Young Adult	2011
Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla. Biological psychiatry, 2011, Jan-01, Volume: 69, Issue:1 Topics: Adult; Age Factors; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuropsychological Tests; Protons; Schizophrenia; Schizophrenic Psychology	2011
Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex. Psychopharmacology, 2011, Volume: 214, Issue:3 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Benzodiazepines; Choice Behavior; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Impulsive Behavior; Male; Microdialysis; Neuropsychological Tests; Olanzapine; Piperazines; Prefrontal Cortex; Quinolones; Rats; Reaction Time; Schizophrenia; Serotonin; Time Factors	2011
Altered social interaction in adult rats following neonatal treatment with domoic acid. Physiology & behavior, 2011, Mar-01, Volume: 102, Issue:3-4 Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Critical Period, Psychological; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Kainic Acid; Male; Rats; Rats, Sprague-Dawley; Schizophrenia; Social Behavior	2011
Prefrontal NMDA receptor antagonism reduces impairments in pre-attentive information processing. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011, Volume: 21, Issue:3 Topics: Animals; Cognition; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Intraperitoneal; Male; Mice; Phencyclidine; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Sensory Gating; Signal Transduction	2011
Homeostatic regulation of glutamatergic transmission by dopamine D4 receptors. Proceedings of the National Academy of Sciences of the United States of America, 2010, Dec-21, Volume: 107, Issue:51 Topics: Animals; Attention Deficit Disorder with Hyperactivity; Glutamic Acid; Homeostasis; Humans; Protein Transport; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Schizophrenia; Synapses; Synaptic Transmission	2010
Dysbindin and Schizophrenia: it's dopamine and glutamate all over again. Biological psychiatry, 2011, Jan-01, Volume: 69, Issue:1 Topics: Animals; Brain; Carrier Proteins; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamic Acid; Humans; Schizophrenia	2011
Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:6 Topics: Aged; Aged, 80 and over; Astrocytes; Biomarkers; Female; Glutamic Acid; Gyrus Cinguli; Humans; Lasers; Male; Microdissection; Nerve Fibers, Myelinated; Schizophrenia	2011
Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT₂A and mGlu₂ receptors in the adult offspring. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-02, Volume: 31, Issue:5 Topics: Adult Children; Animals; Antipsychotic Agents; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Early Growth Response Protein 1; Early Growth Response Protein 2; Female; Frontal Lobe; Glutamic Acid; Hallucinogens; Influenza A Virus, H1N1 Subtype; Maternal-Fetal Exchange; Mice; Neural Pathways; Orthomyxoviridae Infections; Pregnancy; Proto-Oncogene Proteins c-fos; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; Schizophrenia; Up-Regulation	2011
[Development of animal models, and drug discovery for schizophrenia based on the glutamate hypothesis]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2010, Volume: 30, Issue:5-6 Topics: Animals; Disease Models, Animal; Drug Discovery; Glutamic Acid; Humans; Mice; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2010
Developmental GABAergic deficit enhances methamphetamine-induced apoptosis. Psychopharmacology, 2011, Volume: 215, Issue:3 Topics: Animals; Apoptosis; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Situ Nick-End Labeling; Male; Methamphetamine; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Sensory Gating; Time Factors	2011
Higher levels of glutamate in the associative-striatum of subjects with prodromal symptoms of schizophrenia and patients with first-episode psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:9 Topics: Adolescent; Adult; Age of Onset; Caudate Nucleus; Disease Progression; Female; Glutamic Acid; Humans; Male; Psychotic Disorders; Risk Factors; Schizophrenia; Up-Regulation; Young Adult	2011
Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:8 Topics: Adult; Arginine; Carrier Proteins; Cerebral Cortex; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Male; Polymorphism, Genetic; Schizophrenia; Young Adult	2011
Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience, 2012, Volume: 262, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Female; Genetic Association Studies; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Methionine; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Protons; Schizophrenia; Valine; Verbal Learning	2012
Dopamine-glutamate interactions: a neural convergence mechanism of common schizophrenia risk variants. Biological psychiatry, 2011, May-15, Volume: 69, Issue:10 Topics: Dopamine; Glutamic Acid; Humans; Risk Factors; Schizophrenia	2011
In vivo and ex vivo evidence for ketamine-induced hyperglutamatergic activity in the cerebral cortex of the rat: Potential relevance to schizophrenia. NMR in biomedicine, 2011, Volume: 24, Issue:10 Topics: Animals; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Ketamine; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Schizophrenia	2011
Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition. BMC systems biology, 2011, May-16, Volume: 5 Topics: Algorithms; Animals; Cluster Analysis; Cognition; Disease Models, Animal; Gene Expression Regulation; Genome; Glutamic Acid; Humans; Ligands; Models, Biological; Models, Statistical; Phencyclidine; Principal Component Analysis; Rats; Schizophrenia; Software; Systems Biology	2011
Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia. The British journal of psychiatry : the journal of mental science, 2011, Volume: 198, Issue:6 Topics: Activities of Daily Living; Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Brain Mapping; Case-Control Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Participation; Thalamus; Time Factors	2011
[About the NMDA-system again]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2011, Volume: 13, Issue:1 Topics: Alcoholism; Alzheimer Disease; Animals; Antipsychotic Agents; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses	2011
Effect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801. Neuroscience letters, 2011, Aug-18, Volume: 500, Issue:3 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Extracellular Space; Female; Glutamic Acid; Isoxazoles; Male; Maternal Exposure; Paliperidone Palmitate; Poly I-C; Prefrontal Cortex; Pregnancy; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone; Schizophrenia	2011
Is there evidence for neurotoxicity in the prodromal and early stages of schizophrenia? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:9 Topics: Caudate Nucleus; Disease Progression; Glutamic Acid; Humans; Neurotoxins; Schizophrenia	2011
Clozapine, but not haloperidol, enhances glial D-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes. British journal of pharmacology, 2012, Volume: 165, Issue:5 Topics: Animals; Antipsychotic Agents; Astrocytes; Cells, Cultured; Citrates; Clozapine; Glutamic Acid; Haloperidol; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Tetanus Toxin; Tetrodotoxin	2012
Concentration change of DA, DOPAC, Glu and GABA in brain tissues in schizophrenia developmental model rats induced by MK-801. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Dizocilpine Maleate; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Schizophrenia	2011
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development. Biological psychiatry, 2012, Jun-01, Volume: 71, Issue:11 Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia	2012
Is the acute NMDA receptor hypofunction a valid model of schizophrenia? Schizophrenia bulletin, 2012, Volume: 38, Issue:1 Topics: Animals; Corpus Callosum; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Ketamine; Parvalbumins; Phencyclidine; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Rodentia; Schizophrenia; Serotonin	2012
Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine. Psychopharmacology, 2012, Volume: 220, Issue:3 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Cognition; Cognition Disorders; Disease Models, Animal; Galantamine; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Nootropic Agents; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Nicotinic; Schizophrenia	2012
Schizophrenia and the epigenetic hypothesis. Epigenomics, 2010, Volume: 2, Issue:3 Topics: DNA Methylation; Epigenesis, Genetic; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Humans; Interneurons; Pyramidal Cells; Schizophrenia	2010
Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. Archives of general psychiatry, 2012, Volume: 69, Issue:5 Topics: Adult; Case-Control Studies; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Neuroimaging; Prefrontal Cortex; Schizophrenia	2012
Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia. Neuroreport, 2012, Mar-07, Volume: 23, Issue:4 Topics: Aged; Aged, 80 and over; Aging; Equilibrative Nucleoside Transporter 1; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia; Temporal Lobe	2012
Comment regarding increased striatal glutamate in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:4 Topics: Caudate Nucleus; Female; Glutamic Acid; Humans; Male; Psychotic Disorders; Schizophrenia	2012
Alpha7 nicotinic cholinergic neuromodulation may reconcile multiple neurotransmitter hypotheses of schizophrenia. Medical hypotheses, 2012, Volume: 78, Issue:5 Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Cholinergic Agonists; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; Receptors, Nicotinic; Schizophrenia	2012
Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation. Hippocampus, 2012, Volume: 22, Issue:5 Topics: Age Factors; Animals; Conditioning, Psychological; Fear; Female; Gene Expression; Glutamic Acid; Glutaminase; Hippocampus; Inhibition, Psychological; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses; Synaptic Transmission	2012
Glutamatergic changes in the cerebral white matter associated with schizophrenic exacerbation. Acta psychiatrica Scandinavica, 2012, Volume: 126, Issue:1 Topics: Adult; Brain; Brain Chemistry; Case-Control Studies; Disease Progression; Excitatory Amino Acids; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroimaging; Parietal Lobe; Schizophrenia	2012
Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function. Human brain mapping, 2013, Volume: 34, Issue:9 Topics: Adult; Brain; Brain Mapping; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Epistasis, Genetic; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Healthy Volunteers; Humans; Image Processing, Computer-Assisted; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Imaging; Male; Polymorphism, Single Nucleotide; Psychotic Disorders; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Synaptic Transmission; Verbal Learning	2013
Effects of N-acetylaspartylglutamate (NAAG) peptidase inhibition on release of glutamate and dopamine in prefrontal cortex and nucleus accumbens in phencyclidine model of schizophrenia. The Journal of biological chemistry, 2012, Jun-22, Volume: 287, Issue:26 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dopamine; Glutamate Carboxypeptidase II; Glutamic Acid; Male; Neurotransmitter Agents; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia	2012
Evidence for involvement of nitric oxide and GABA(B) receptors in MK-801- stimulated release of glutamate in rat prefrontal cortex. Neuropharmacology, 2012, Volume: 63, Issue:4 Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA-B Receptor Agonists; Glutamic Acid; Male; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2012
Common variants in MAGI2 gene are associated with increased risk for cognitive impairment in schizophrenic patients. PloS one, 2012, Volume: 7, Issue:5 Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Case-Control Studies; Cognition Disorders; Genetic Association Studies; Genetic Predisposition to Disease; Glutamic Acid; Guanylate Kinases; Humans; Japan; Neuropsychological Tests; Polymorphism, Single Nucleotide; Schizophrenia	2012
Biological perspectives: the role of glutamate in schizophrenia and its treatment. Perspectives in psychiatric care, 2012, Volume: 48, Issue:3 Topics: Antipsychotic Agents; Dopamine; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Receptors, Glycine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2012
Cognitive dysfunction and glutamate reuptake: effect of EAAT2 polymorphism in schizophrenia. Neuroscience letters, 2012, Aug-01, Volume: 522, Issue:2 Topics: Adolescent; Adult; Cognition Disorders; Excitatory Amino Acid Transporter 2; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Memory, Short-Term; Middle Aged; Polymorphism, Genetic; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Young Adult	2012
Anterior cingulate glutamate levels related to clinical status following treatment in first-episode schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11 Topics: Adult; Antipsychotic Agents; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Protons; Psychiatric Status Rating Scales; Radionuclide Imaging; Schizophrenia; Young Adult	2012
Regional decoupling of N-acetyl-aspartate and glutamate in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:12 Topics: Adult; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Female; Glutamic Acid; Hippocampus; Homeostasis; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	2012
Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging. Schizophrenia research, 2012, Volume: 140, Issue:1-3 Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxygen; Protons; Schizophrenia; Young Adult	2012
Twenty-five years of glutamate in schizophrenia: are we there yet? Schizophrenia bulletin, 2012, Volume: 38, Issue:5 Topics: Antipsychotic Agents; Glutamic Acid; History, 20th Century; History, 21st Century; Humans; Phencyclidine; Psychoses, Substance-Induced; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2012
NMDA receptor and schizophrenia: a brief history. Schizophrenia bulletin, 2012, Volume: 38, Issue:5 Topics: Anesthetics, Dissociative; Animals; Antipsychotic Agents; Disease Models, Animal; Glutamic Acid; History, 20th Century; History, 21st Century; Humans; Neurosciences; Phencyclidine Abuse; Psychopharmacology; Psychoses, Substance-Induced; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Translational Research, Biomedical	2012
Direct and indirect interactions of the dopamine D₃ receptor with glutamate pathways: implications for the treatment of schizophrenia. Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:2 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Mice; Motor Activity; Nucleus Accumbens; Piperazines; Rats; Receptors, Dopamine D3; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2013
Proteomic analysis of the maternal protein restriction rat model for schizophrenia: identification of translational changes in hormonal signaling pathways and glutamate neurotransmission. Proteomics, 2012, Volume: 12, Issue:23-24 Topics: Animals; Blood Glucose; Brain; Female; Fetal Nutrition Disorders; Gene Expression Profiling; Glutamic Acid; Humans; Insulin; Pregnancy; Protein Deficiency; Proteome; Proteomics; Rats; Rats, Wistar; Schizophrenia; Serum; Signal Transduction; Synaptic Transmission	2012
In vivo measurements of glutamate, GABA, and NAAG in schizophrenia. Schizophrenia bulletin, 2013, Volume: 39, Issue:5 Topics: Adult; Age Factors; Attention; Cerebrum; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Severity of Illness Index; Young Adult	2013
Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia. Neuroreport, 2012, Dec-05, Volume: 23, Issue:17 Topics: Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Egg Proteins; Female; Frontal Lobe; Gene Expression Regulation; Genetic Markers; Genetic Predisposition to Disease; Glutamic Acid; Haloperidol; Humans; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Prefrontal Cortex; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Schizophrenia; Synaptic Transmission; Up-Regulation	2012
Somatic transposition in the brain has the potential to influence the biosynthesis of metabolites involved in Parkinson's disease and schizophrenia. Biology direct, 2012, Nov-23, Volume: 7 Topics: Brain; Computational Biology; DNA Transposable Elements; Dopamine; Glutamic Acid; Humans; Neurotransmitter Agents; Organ Specificity; Parkinson Disease; Schizophrenia; Serotonin	2012
Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia. Schizophrenia research, 2013, Volume: 144, Issue:1-3 Topics: Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Haloperidol; Hippocampus; Humans; Male; Rats; Rats, Sprague-Dawley; Schizophrenia; Temporal Lobe; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2; Vesicular Glutamate Transport Proteins	2013
Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers. The American journal of psychiatry, 2002, Volume: 159, Issue:11 Topics: Adult; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Schizophrenic Psychology; Thalamus	2002
Interaction of stress and strain on glutamatergic neurotransmission: relevance to schizophrenia. Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2 Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Mice; Mice, Inbred BALB C; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Species Specificity; Stress, Psychological; Synaptic Transmission	2003
Some possible genetic parallels across alcoholism, bipolar disorder and schizophrenia. Journal of studies on alcohol, 2003, Volume: 64, Issue:2 Topics: Alcoholism; Bipolar Disorder; Catecholamines; Chromosome Deletion; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 22; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Schizophrenia	2003
Effect of antipsychotic drugs on brain-derived neurotrophic factor expression under reduced N-methyl-D-aspartate receptor activity. Journal of neuroscience research, 2003, Jun-01, Volume: 72, Issue:5 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Brain-Derived Neurotrophic Factor; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Male; Neuronal Plasticity; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Synaptic Transmission	2003
Psychiatric drugs. Excited by glutamate. Science (New York, N.Y.), 2003, Jun-20, Volume: 300, Issue:5627 Topics: Animals; Anxiety Disorders; Brain; Brain Diseases; Bridged Bicyclo Compounds; Clinical Trials as Topic; Depressive Disorder; Dopamine; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mental Disorders; Neurons; Pain; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Substance-Related Disorders; Synaptic Transmission	2003
Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:9 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Analysis of Variance; Animals; Area Under Curve; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Hyperkinesis; In Vitro Techniques; Ketamine; Male; Microdialysis; Motor Activity; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Metabotropic Glutamate; Schizophrenia; Serotonin; Sulfur Isotopes; Time Factors; Trifluoroethanol; Xanthenes	2003
Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America, 2003, Jul-22, Volume: 100, Issue:15 Topics: Amphetamine; Animals; Behavior, Animal; Calcineurin; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Schizophrenia; Signal Transduction; Social Behavior	2003
Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Molecular psychiatry, 2003, Volume: 8, Issue:6 Topics: Adolescent; Adult; Aged; Blotting, Northern; Blotting, Western; Brain-Derived Neurotrophic Factor; Cohort Studies; Female; Glutamic Acid; Humans; In Situ Hybridization; Male; Middle Aged; Prefrontal Cortex; RNA, Messenger; Schizophrenia	2003
The urinary excretion of glutamine and glutamic acid in normals and in a group of psychiatric patients. Scandinavian journal of clinical and laboratory investigation, 1954, Volume: 6, Issue:2 Topics: Glutamates; Glutamic Acid; Glutamine; Humans; Schizophrenia; Urine	1954
[METABOLIC EFFECTS OF THE GAMMA-ETHYLESTER OF 1-GLUTAMIC ACID IN SAKEL'S HYPOGLYCEMIC COMA]. Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1964, Mar-31, Volume: 88 Topics: Coma; Convulsive Therapy; Gamma Rays; Glutamates; Glutamic Acid; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Schizophrenia	1964
Drug-induced parkinsonism in relation to choline-containing compounds measured by 1H-MR spectroscopy in putamen of chronically medicated patients with schizophrenia. The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:4 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia Diseases; Choline; Chronic Disease; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurologic Examination; Parkinson Disease, Secondary; Phosphocreatine; Putamen; Reference Values; Schizophrenia; Schizophrenic Psychology	2003
Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. The American journal of psychiatry, 2003, Volume: 160, Issue:12 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Thalamus	2003
Decoding schizophrenia. Scientific American, 2004, Volume: 290, Issue:1 Topics: Antipsychotic Agents; Brain; Clozapine; Dopamine; Glutamic Acid; Humans; Neurotransmitter Agents; Perception; Phencyclidine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction	2004
Disruption of prepulse inhibition in mice lacking mGluR1. The European journal of neuroscience, 2003, Volume: 18, Issue:12 Topics: Acoustic Stimulation; Animals; Antimanic Agents; Brain; Disease Models, Animal; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Lamotrigine; Male; Mice; Mice, Knockout; Neural Inhibition; Receptors, Metabotropic Glutamate; Reflex, Startle; Schizophrenia; Synaptic Transmission; Triazines	2003
Schizophrenia, dissociative anaesthesia and near-death experience; three events meeting at the NMDA receptor. Medical hypotheses, 2004, Volume: 62, Issue:1 Topics: Anesthetics, Dissociative; Animals; Brain; Death; Glutamic Acid; Glycine; Humans; Models, Biological; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Statistics as Topic	2004
Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats. Neuroscience letters, 2004, Jan-23, Volume: 355, Issue:1-2 Topics: Animals; Apomorphine; Denervation; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ibotenic Acid; Male; Neural Inhibition; Neural Pathways; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Synaptic Transmission	2004
[Glutamine and glutamic acid metabolism, with special reference to nervous tissue and psychiatric disease]. Nordisk medicin, 1951, Jan-24, Volume: 45, Issue:4 Topics: Glutamic Acid; Glutamine; Humans; Nerve Tissue; Psychotic Disorders; Schizophrenia	1951
Dysbindin-1 and schizophrenia: from genetics to neuropathology. The Journal of clinical investigation, 2004, Volume: 113, Issue:9 Topics: Brain; Carrier Proteins; Dysbindin; Dystrophin-Associated Proteins; Genetic Predisposition to Disease; Glutamic Acid; Hippocampus; Humans; Membrane Transport Proteins; Models, Biological; Neurons; Presynaptic Terminals; Schizophrenia; Tissue Distribution; Vesicular Glutamate Transport Protein 1; Vesicular Transport Proteins	2004
3-T proton MRS investigation of glutamate and glutamine in adolescents at high genetic risk for schizophrenia. The American journal of psychiatry, 2004, Volume: 161, Issue:6 Topics: Adolescent; Child of Impaired Parents; Cohort Studies; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Social Class	2004
Kynurenic acid and schizophrenia. Advances in experimental medicine and biology, 2003, Volume: 527 Topics: Animals; Antipsychotic Agents; Dopamine; Glutamic Acid; Humans; Kynurenic Acid; Male; Models, Neurological; Phencyclidine; Psychoses, Substance-Induced; Rats; Rats, Sprague-Dawley; Schizophrenia; Ventral Tegmental Area	2003
The dopaminergic stabiliser ACR16 counteracts the behavioural primitivization induced by the NMDA receptor antagonist MK-801 in mice: implications for cognition. Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:4 Topics: Animals; Autistic Disorder; Behavior, Animal; Cognition; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Grooming; Haloperidol; Hyperkinesis; Male; Mice; Motor Activity; Piperidines; Schizophrenia	2004
Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor. Journal of medicinal chemistry, 2004, Aug-26, Volume: 47, Issue:18 Topics: Acetophenones; Allosteric Regulation; Animals; Behavior; Brain; Dose-Response Relationship, Drug; Glutamic Acid; Hyperkinesis; Norepinephrine; Rats; Receptors, Metabotropic Glutamate; Schizophrenia; Structure-Activity Relationship	2004
Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Human molecular genetics, 2004, Nov-01, Volume: 13, Issue:21 Topics: Adult; Alleles; Animals; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Chromones; Chromosomes, Human, Pair 6; Dysbindin; Dystrophin-Associated Proteins; Enzyme Inhibitors; Female; Gene Frequency; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Glutamic Acid; Haplotypes; Humans; Linkage Disequilibrium; Male; Membrane Proteins; Morpholines; Nerve Tissue Proteins; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Strains; RNA, Small Interfering; Schizophrenia; Synapsins; Synaptosomal-Associated Protein 25	2004
[Glutamic acid therapy of schizophrenia]. Ugeskrift for laeger, 1950, Apr-06, Volume: 112, Issue:14 Topics: Glutamic Acid; Humans; Schizophrenia	1950
Ketamine induces dopamine-dependent depression of evoked hippocampal activity in the nucleus accumbens in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jan-12, Volume: 25, Issue:2 Topics: Animals; Disease Models, Animal; Dopamine; Electric Stimulation; Evoked Potentials; Fornix, Brain; Glutamic Acid; Hippocampus; Ketamine; Male; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission	2005
Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study. Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3 Topics: Adult; Aspartic Acid; Chronic Disease; Diagnostic and Statistical Manual of Mental Disorders; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Protons; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Synaptic Transmission	2005
Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophrenia research, 2005, Mar-01, Volume: 73, Issue:2-3 Topics: Adaptor Proteins, Vesicular Transport; Adult; Aged; Aged, 80 and over; Female; Gene Expression; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; In Situ Hybridization; Male; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neurons; Prefrontal Cortex; RNA, Messenger; Schizophrenia; Synapses; Synaptic Transmission; Temporal Lobe; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2	2005
Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients. BMC psychiatry, 2005, Jan-31, Volume: 5 Topics: Adolescent; Adult; Brain Chemistry; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Humans; Male; Reference Values; Schizophrenia	2005
Memantine as a neuroprotective treatment in schizophrenia. The British journal of psychiatry : the journal of mental science, 2005, Volume: 186 Topics: Calcium; Glutamic Acid; Humans; Memantine; Neurons; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2005
Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures. Glia, 2005, Volume: 50, Issue:3 Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Antipsychotic Agents; Astrocytes; Cells, Cultured; Cerebral Cortex; Clozapine; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Rats; Rats, Sprague-Dawley; Schizophrenia; Symporters; Synaptic Transmission	2005
Cortical glutamatergic markers in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:8 Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; In Situ Hybridization; Kainic Acid; Male; Middle Aged; Postmortem Changes; Radioligand Assay; Receptors, Glutamate; Schizophrenia; Tritium	2005
Isolation rearing or methamphetamine traumatisation induce a "dysconnection" of prefrontal efferents in gerbils: implications for schizophrenia. Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:3 Topics: Animals; Central Nervous System Stimulants; Cerebral Cortex; Disease Models, Animal; Dopamine; Efferent Pathways; Gerbillinae; Glutamic Acid; Lysine; Male; Methamphetamine; Models, Neurological; Parietal Lobe; Prefrontal Cortex; Presynaptic Terminals; Schizophrenia; Social Isolation; Synaptic Transmission	2006
Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia. Genes, brain, and behavior, 2005, Volume: 4, Issue:5 Topics: Animals; Behavior, Animal; Carrier Proteins; Conditioning, Operant; Exploratory Behavior; Female; Frontal Lobe; Gene Deletion; Glutamic Acid; Homer Scaffolding Proteins; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Nucleus Accumbens; Phenotype; Polymorphism, Single Nucleotide; Schizophrenia	2005
Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study. Biological psychiatry, 2005, Nov-01, Volume: 58, Issue:9 Topics: Adult; Analysis of Variance; Chronic Disease; Electroencephalography; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Synapses	2005
Dopamine prevents muscarinic-induced decrease of glutamate release in the auditory cortex. Neuroscience, 2005, Volume: 134, Issue:4 Topics: Animals; Antipsychotic Agents; Auditory Cortex; Dopamine; Excitatory Postsynaptic Potentials; Glutamic Acid; Muscarinic Agonists; Neurons; Organ Culture Techniques; Oxotremorine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Muscarinic; Schizophrenia	2005
Glial-neuronal interactions are impaired in the schizophrenia model of repeated MK801 exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:9 Topics: Acetates; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Glucose; Glutamic Acid; Glutamine; Isotope Labeling; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Schizophrenia	2006
DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling. Human molecular genetics, 2006, Mar-01, Volume: 15, Issue:5 Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Bipolar Disorder; Calcium Channels; Chromosome Aberrations; Chromosomes, Artificial, Bacterial; Cohort Studies; DNA Primers; Frontal Lobe; Gene Dosage; Genetic Variation; Genome, Human; GluK3 Kainate Receptor; Glutamic Acid; Humans; Nucleic Acid Hybridization; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Signal Transduction	2006
Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophrenia. Synapse (New York, N.Y.), 2006, Jun-01, Volume: 59, Issue:7 Topics: Aged; Aged, 80 and over; Animals; Antipsychotic Agents; Clozapine; COP9 Signalosome Complex; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Guanine Nucleotide Exchange Factors; Haloperidol; Heat-Shock Proteins; Humans; Image Processing, Computer-Assisted; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Male; Membrane Transport Proteins; Middle Aged; Rats; Rats, Sprague-Dawley; Rho Guanine Nucleotide Exchange Factors; RNA, Messenger; Schizophrenia; Thalamus; Transcription, Genetic	2006
Cortical microcircuits in schizophrenia--the dopamine hypothesis revisited. Pharmacopsychiatry, 2006, Volume: 39 Suppl 1 Topics: Cerebral Cortex; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Internal-External Control; Nerve Net; Neural Inhibition; Prefrontal Cortex; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Synapses	2006
Excitatory aminoacid neurotransmitters in schizophrenia. Bangladesh Medical Research Council bulletin, 2005, Volume: 31, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Bangladesh; Case-Control Studies; Disease Progression; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia	2005
Neonatal exposure to MK801 induces structural reorganization of the central nervous system. Neuroreport, 2006, May-29, Volume: 17, Issue:8 Topics: Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Caspases; Cytoskeleton; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Microtubule-Associated Proteins; Nerve Net; Neural Pathways; Neuronal Plasticity; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Somatosensory Cortex; Synaptosomal-Associated Protein 25; tau Proteins	2006
Effects of topiramate on the prepulse inhibition of the acoustic startle in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2 Topics: Animals; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Brain; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Fructose; Glutamic Acid; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Synaptic Transmission; Topiramate	2007
Regulation of NAA-synthesis in the human brain in vivo: Canavan's disease, Alzheimer's disease and schizophrenia. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Alzheimer Disease; Aspartic Acid; Brain; Canavan Disease; Child; Glutamic Acid; Humans; Magnetic Resonance Imaging; Molecular Structure; Schizophrenia	2006
Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study. Journal of psychiatric research, 2007, Volume: 41, Issue:8 Topics: Adult; Aged; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Cognition Disorders; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Recall; Middle Aged; Neurons; Phosphocreatine; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Verbal Learning	2007
Regarding "Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study". Biological psychiatry, 2007, May-15, Volume: 61, Issue:10 Topics: Aspartic Acid; Choline; Creatine; Dominance, Cerebral; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Phosphocreatine; Prefrontal Cortex; Reference Values; Schizophrenia; Thalamus	2007
Lamina-specific abnormalities of AMPA receptor trafficking and signaling molecule transcripts in the prefrontal cortex in schizophrenia. Synapse (New York, N.Y.), 2006, Dec-15, Volume: 60, Issue:8 Topics: Adult; Aged; Binding, Competitive; Calcium Channels; Carrier Proteins; Female; Glutamic Acid; Humans; Male; Membrane Proteins; Middle Aged; Nuclear Proteins; Prefrontal Cortex; Protein Transport; Radioligand Assay; Receptor Aggregation; Receptors, AMPA; RNA, Messenger; Schizophrenia; Signal Transduction; Synaptic Membranes; Synaptic Transmission	2006
Increased expression of activity-dependent genes in cerebellar glutamatergic neurons of patients with schizophrenia. The American journal of psychiatry, 2006, Volume: 163, Issue:10 Topics: Adult; Aged; Brain-Derived Neurotrophic Factor; Cerebellar Cortex; Cerebellum; Female; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation; Glutamic Acid; Humans; Male; Middle Aged; Neurons; Receptors, GABA-A; RNA, Messenger; Schizophrenia	2006
Role of the simultaneous enhancement of NMDA and dopamine D1 receptor-mediated neurotransmission in the effects of clozapine on phencyclidine-induced acute increases in glutamate levels in the rat medial prefrontal cortex. Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:3 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Drug Resistance; Glutamic Acid; Haloperidol; Humans; Male; Microdialysis; Motor Activity; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2006
Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder. Brain research, 2007, Jan-05, Volume: 1127, Issue:1 Topics: Binding Sites; Binding, Competitive; Biomarkers; Bipolar Disorder; Down-Regulation; Female; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Male; Nuclear Proteins; Predictive Value of Tests; Presynaptic Terminals; Protein Transport; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Synaptic Transmission; Transcription Factors	2007
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophrenia research, 2007, Volume: 90, Issue:1-3 Topics: Adolescent; Adult; Aged; Brain; D-Amino-Acid Oxidase; Female; Frontal Lobe; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Middle Aged; Parietal Lobe; Racemases and Epimerases; Reference Values; Schizophrenia; Serine	2007
Schizophrenia: more evidence for less glutamate. Expert review of neurotherapeutics, 2007, Volume: 7, Issue:1 Topics: Animals; Brain; Cadaver; Disease Models, Animal; ErbB Receptors; Evidence-Based Medicine; Glutamic Acid; Humans; Mice; Mice, Inbred C3H; Neuregulin-1; Prefrontal Cortex; Receptor, ErbB-4; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction	2007
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia. Biological psychiatry, 2007, Oct-01, Volume: 62, Issue:7 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia	2007
The tripartite synapse: roles for gliotransmission in health and disease. Trends in molecular medicine, 2007, Volume: 13, Issue:2 Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium Signaling; Epilepsy; Glutamic Acid; Humans; Models, Neurological; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Spinal Cord Injuries; Synapses; Synaptic Transmission	2007
Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2007, Mar-05, Volume: 144B, Issue:2 Topics: Animals; Behavior, Animal; Biomarkers; Clozapine; gamma-Aminobutyric Acid; Gene Expression Regulation; Genetic Linkage; Genomics; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Myelin Sheath; Neurotransmitter Agents; Phencyclidine; Reproducibility of Results; Schizophrenia	2007
High glycine levels are associated with prepulse inhibition deficits in chronic schizophrenia patients. Schizophrenia research, 2007, Volume: 91, Issue:1-3 Topics: Adult; Blinking; Chronic Disease; Electromyography; Female; Glutamic Acid; Glycine; Humans; Inhibition, Psychological; Ketamine; Male; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Severity of Illness Index	2007
Alterations in prefrontal glutamatergic and noradrenergic systems following MK-801 administration in rats prenatally exposed to methylazoxymethanol at gestational day 17. Psychopharmacology, 2007, Volume: 192, Issue:3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Male; Methylazoxymethanol Acetate; Microdialysis; Motor Activity; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2007
Further evidence for altered myelin biosynthesis and glutamatergic dysfunction in schizophrenia. The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:4 Topics: Adult; Aged; Amidohydrolases; Aspartic Acid; Cadaver; Case-Control Studies; Fatty Acids; Female; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Male; Middle Aged; Myelin Sheath; Oligodendroglia; Prefrontal Cortex; Receptors, Metabotropic Glutamate; RNA, Messenger; Schizophrenia; Synaptic Transmission	2007
Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:10 Topics: Animals; Brain; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Phencyclidine; Piperidines; Psychoses, Substance-Induced; Pyrazoles; Rats; Receptors, Cannabinoid; Reflex, Startle; Rimonabant; Schizophrenia; Sensation Disorders; Synaptic Transmission	2007
Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia. Journal of neuroscience research, 2007, Nov-15, Volume: 85, Issue:15 Topics: Animals; Astrocytes; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Dopamine; Energy Metabolism; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neurons; Schizophrenia; Synaptic Vesicles	2007
Ketamine-related expression of glutamatergic postsynaptic density genes: possible implications in psychosis. Neuroscience letters, 2007, Apr-06, Volume: 416, Issue:1 Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cerebral Cortex; Dopamine Plasma Membrane Transport Proteins; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Homer Scaffolding Proteins; Ketamine; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; RNA, Messenger; Schizophrenia; Synapses	2007
Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:10 Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Haloperidol; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Schizophrenia; Serotonin; Synaptic Transmission	2007
The neuronal pathology of schizophrenia: molecules and mechanisms. Biochemical Society transactions, 2007, Volume: 35, Issue:Pt 2 Topics: Animals; Aspartic Acid; Brain; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Neurons; Phencyclidine; Schizophrenia	2007
Failure to confirm the association between the FEZ1 gene and schizophrenia in a Japanese population. Neuroscience letters, 2007, May-07, Volume: 417, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Adult; Amino Acid Substitution; Asian People; Aspartic Acid; Brain; Brain Chemistry; DNA Mutational Analysis; DNA-Binding Proteins; Female; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glutamic Acid; Humans; Japan; Male; Middle Aged; Mutation; Mutation, Missense; Nerve Tissue Proteins; Polymorphism, Genetic; Schizophrenia; Tumor Suppressor Proteins	2007
Antipsychotic drugs reverse the AMPA receptor-stimulated release of 5-HT in the medial prefrontal cortex. Journal of neurochemistry, 2007, Volume: 102, Issue:2 Topics: Adrenergic alpha-1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Male; Microdialysis; Neural Inhibition; Norepinephrine; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Synaptic Transmission; Thalamus	2007
Systemic neurochemical alterations in schizophrenic brain: glutamate metabolism in focus. Neurochemical research, 2007, Volume: 32, Issue:9 Topics: Adult; Age Factors; Aged; Brain; Caudate Nucleus; Cerebellar Cortex; Creatine Kinase, BB Form; Energy Metabolism; Glial Fibrillary Acidic Protein; Glutamate Dehydrogenase (NADP+); Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Middle Aged; Myelin Basic Protein; Prefrontal Cortex; Schizophrenia	2007
(+/-) Ketamine-induced prepulse inhibition deficits of an acoustic startle response in rats are not reversed by antipsychotics. Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:3 Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Ketamine; Lamotrigine; Male; Pyridines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone; Schizophrenia; Sulfonamides; Thiophenes; Triazines	2007
The genetics of schizophrenia converge upon the NMDA glutamate receptor. CNS spectrums, 2007, Volume: 12, Issue:8 Topics: Brain; Genetic Predisposition to Disease; Glutamic Acid; Humans; Long-Term Potentiation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses	2007
Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia -- Juntendo University Schizophrenia Projects (JUSP). Progress in neuro-psychopharmacology & biological psychiatry, 2007, Oct-01, Volume: 31, Issue:7 Topics: Adult; Antipsychotic Agents; DNA; Female; Genotype; Glutamic Acid; Glutaminase; Haplotypes; Humans; Isoenzymes; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Schizophrenia	2007
Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors. Molecular psychiatry, 2008, Volume: 13, Issue:6 Topics: Acclimatization; Animals; Corpus Striatum; Crosses, Genetic; Disease Models, Animal; Dopamine; Female; Glutamic Acid; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptors, AMPA; Schizophrenia; Social Behavior	2008
Brain metabolite abnormalities in the white matter of elderly schizophrenic subjects: implication for glial dysfunction. Biological psychiatry, 2007, Dec-15, Volume: 62, Issue:12 Topics: Aged; Alanine; Brain; Brain Mapping; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Protons; Schizophrenia	2007
Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:7 Topics: Acetylcysteine; Aged; Aged, 80 and over; Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Fluid; Female; Free Radical Scavengers; Glutamic Acid; Glycine; Humans; Interpersonal Relations; Male; Maze Learning; Microdialysis; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Xanthenes	2008
Frontolimbic glutamate alterations in first episode schizophrenia: evidence from a magnetic resonance spectroscopy study. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2008, Volume: 9, Issue:1 Topics: Adult; Amygdala; Brief Psychiatric Rating Scale; Female; Frontal Lobe; Functional Laterality; Glutamic Acid; Hippocampus; Humans; Limbic System; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Schizophrenia; Time Factors	2008
Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia. The British journal of psychiatry : the journal of mental science, 2007, Volume: 191 Topics: Adult; Case-Control Studies; Female; Functional Laterality; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Thalamus; Time Factors	2007
Altered pre-pulse inhibition in adult rats treated neonatally with domoic acid. Amino acids, 2008, Volume: 35, Issue:1 Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Glutamic Acid; Humans; Kainic Acid; Male; Neuromuscular Depolarizing Agents; Rats; Reflex, Acoustic; Reflex, Startle; Schizophrenia; Sex Factors; Time Factors	2008
A preliminary study of the effects of glutamic acid on catatonic schizophrenics. Rorschach research exchange and journal of projective techniques, 1949, Volume: 13, Issue:2 Topics: Catatonia; Glutamic Acid; Humans; Schizophrenia	1949
Elevated 3T proton MRS glutamate levels associated with poor Continuous Performance Test (CPT-0X) scores and genetic risk for schizophrenia. Schizophrenia research, 2008, Volume: 99, Issue:1-3 Topics: Adult; Attention; Cognition Disorders; Creatine; Discrimination, Psychological; Female; Frontal Lobe; Genetic Predisposition to Disease; Glutamic Acid; Humans; Inhibition, Psychological; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Pattern Recognition, Visual; Psychomotor Performance; Reaction Time; Risk; Schizophrenia; Schizophrenic Psychology; Schizotypal Personality Disorder; Siblings	2008
Olanzapine and risperidone block a high dose of methamphetamine-induced schizophrenia-like behavioral abnormalities and accompanied apoptosis in the medial prefrontal cortex. Schizophrenia research, 2008, Volume: 101, Issue:1-3 Topics: Animals; Antipsychotic Agents; Apoptosis; Behavior, Animal; Benzodiazepines; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; In Situ Nick-End Labeling; Male; Methamphetamine; Motor Activity; Neural Inhibition; Neuroprotective Agents; Olanzapine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Time Factors	2008
Effects of chronic amphetamine treatment on the glutamate concentration in cerebrospinal fluid and brain: implications for a theory of schizophrenia. Neuroscience letters, 1981, Jun-12, Volume: 24, Issue:1 Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dextroamphetamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Humans; Male; Rats; Schizophrenia; Tissue Distribution	1981
Normal cerebrospinal fluid and brain glutamate levels in schizophrenia do not support the hypothesis of glutamatergic neuronal dysfunction. Neuroscience letters, 1982, Jan-22, Volume: 28, Issue:1 Topics: Adult; Brain; Glutamates; Glutamic Acid; Humans; Huntington Disease; Middle Aged; Schizophrenia	1982
[Quantitative analysis of gamma-aminobutyric acid and glutamic acid in the cerebrospinal fluid of schizophrenics]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1982, Volume: 15, Issue:2 Topics: Adolescent; Adult; Age Factors; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia	1982
Amino acid levels in schizophrenia and celiac disease: another look. Biological psychiatry, 1982, Volume: 17, Issue:11 Topics: Amino Acids; Celiac Disease; Glutamates; Glutamic Acid; Humans; Schizophrenia	1982
Increased serum glutamate in depressed patients. Archiv fur Psychiatrie und Nervenkrankheiten, 1982, Volume: 232, Issue:4 Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia	1982
Cerebral glutamate, neuroleptic drugs and schizophrenia: increase of cerebrospinal fluid glutamate levels and decrease of striate body glutamate levels following sulpiride treatment in rats. European neurology, 1983, Volume: 22, Issue:5 Topics: Animals; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Hippocampus; Humans; Male; Muridae; Receptors, Dopamine; Schizophrenia; Substantia Nigra; Sulpiride	1983
Interactions of cholecystokinin octapeptide and dopamine on nucleus accumbens neurons. Brain research, 1984, May-21, Volume: 300, Issue:1 Topics: Animals; Antipsychotic Agents; Dopamine; Drug Interactions; Glutamates; Glutamic Acid; Humans; Male; Nucleus Accumbens; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholecystokinin; Schizophrenia; Septal Nuclei; Sincalide	1984
[A biochemical theory of schizophrenia]. Der Nervenarzt, 1984, Volume: 55, Issue:11 Topics: Animals; Antipsychotic Agents; Brain; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neurocognitive Disorders; Neurotransmitter Agents; Rats; Receptors, Dopamine; Schizophrenia	1984
The NMDA receptor as a site for psychopathology. Primary or secondary role? Archives of general psychiatry, 1995, Volume: 52, Issue:12 Topics: Glutamic Acid; Humans; Psychopathology; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia	1995
Effects of haloperidol on CSF glutamate levels in drug-naive schizophrenic patients. Schizophrenia research, 1995, Volume: 16, Issue:1 Topics: Adolescent; Adult; Dopamine Antagonists; Female; Glutamic Acid; Haloperidol; Humans; Male; Schizophrenia	1995
Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: evidence for glutamate hypothesis. Biological psychiatry, 1994, Jan-15, Volume: 35, Issue:2 Topics: Adult; Aged; Brain Mapping; Cerebral Cortex; Chronic Disease; Female; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Radioligand Assay; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Strychnine; Up-Regulation	1994
Reduced [3H]flunitrazepam binding in cingulate cortex and hippocampus of postmortem schizophrenic brains: is selective loss of glutamatergic neurons associated with major psychoses? Neurochemical research, 1993, Volume: 18, Issue:2 Topics: Adult; Autopsy; Brain; Cell Count; Female; Flunitrazepam; Glutamates; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Male; Membranes; Middle Aged; Neurons; Receptors, GABA-A; Schizophrenia; Tritium	1993
Amantadine and the glutamate hypothesis of schizophrenia. Experiences in the treatment of neuroleptic malignant syndrome. Journal of neural transmission. General section, 1993, Volume: 92, Issue:1 Topics: Adult; Amantadine; Antipsychotic Agents; Depressive Disorder; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Schizophrenia; Schizophrenic Psychology	1993
The macrophage-T-lymphocyte theory of schizophrenia: additional evidence. Medical hypotheses, 1995, Volume: 45, Issue:2 Topics: Acetylcholine; Animals; Cytokines; Evoked Potentials, Auditory; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Interleukin-2; Locus Coeruleus; Lymphocyte Activation; Macrophage Activation; Macrophages; Models, Immunological; Models, Neurological; Nitric Oxide; Norepinephrine; Schizophrenia; Serotonin; T-Lymphocytes	1995
Glutamate agonist activity: implications for antipsychotic drug action and schizophrenia. Neuroreport, 1995, Dec-15, Volume: 6, Issue:18 Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Schizophrenia	1995
Development of the glutamate, GABA, and dopamine systems in relation to NRH-induced neurotoxicity. Biological psychiatry, 1995, Dec-15, Volume: 38, Issue:12 Topics: Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Limbic System; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia	1995
Glutamate pharmacology and the treatment of schizophrenia: current status and future directions. International clinical psychopharmacology, 1995, Volume: 10 Suppl 3 Topics: Autoradiography; Blood Flow Velocity; Cerebrovascular Circulation; Glutamic Acid; Hippocampus; Humans; Ketamine; Neurotransmitter Agents; RNA, Messenger; Schizophrenia	1995
An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients. Schizophrenia bulletin, 1996, Volume: 22, Issue:4 Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	1996
Glycyldodecylamide, a phencyclidine behavioral antagonist, blocks cortical glycine uptake: implications for schizophrenia and substance abuse. Psychopharmacology, 1997, Volume: 129, Issue:1 Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Phencyclidine; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Schizophrenia; Substance-Related Disorders; Synaptosomes	1997
Deficits of [3H]D-aspartate binding to glutamate uptake sites in striatal and accumbens tissue in patients with schizophrenia. Neuroscience letters, 1997, Aug-22, Volume: 232, Issue:1 Topics: Aged; Animals; Aspartic Acid; Corpus Striatum; Female; Frontal Lobe; Glutamic Acid; Humans; Male; Middle Aged; Nucleus Accumbens; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glutamate; Schizophrenia; Synaptic Membranes; Tritium	1997
Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy. Archives of general psychiatry, 1997, Volume: 54, Issue:10 Topics: Adolescent; Adult; Aspartic Acid; Educational Status; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Schizophrenia; Sex Factors; Tomography, Emission-Computed	1997
Cellular and molecular neuropathology of schizophrenia: new directions from developmental neurobiology. Schizophrenia research, 1997, Oct-30, Volume: 27, Issue:2-3 Topics: Biomarkers; Brain; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Nerve Growth Factors; Neurotransmitter Agents; Neurotrophin 3; Schizophrenia; Transcription Factors	1997
Clozapine treatment increases serum glutamate and aspartate compared to conventional neuroleptics. Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:6-7 Topics: Adult; Antipsychotic Agents; Aspartic Acid; Clozapine; Female; Glutamic Acid; Humans; Linear Models; Male; Middle Aged; Schizophrenia	1997
Increased density of entorhinal glutamate-immunoreactive vertical fibers in schizophrenia. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:4 Topics: Cadaver; Entorhinal Cortex; Glutamic Acid; Humans; Immunohistochemistry; Nerve Fibers; Reference Values; Regression Analysis; Schizophrenia	1996
Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science (New York, N.Y.), 1998, Aug-28, Volume: 281, Issue:5381 Topics: Animals; Bridged Bicyclo Compounds; Disease Models, Animal; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Memory; Motor Activity; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Schizophrenia; Stereotyped Behavior; Synaptic Transmission	1998
A new route to treating schizophrenia? Science (New York, N.Y.), 1998, Aug-28, Volume: 281, Issue:5381 Topics: Animals; Bridged Bicyclo Compounds; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Maze Learning; Memory; Phencyclidine; Prefrontal Cortex; Rats; Receptors, Metabotropic Glutamate; Schizophrenia	1998
What is the role of glutamate in schizophrenia? The Harvard mental health letter, 1999, Volume: 15, Issue:10 Topics: Cycloserine; Glutamic Acid; Glycine; Humans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia	1999
Dopamine D1 receptor modulation of glutamate receptor messenger RNA levels in the neocortex and neostriatum of unilaterally 6-hydroxydopamine-lesioned rats. Neuroscience, 1999, Volume: 89, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Drug Design; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; Male; Motor Activity; Neocortex; Nerve Tissue Proteins; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; RNA, Messenger; Schizophrenia; Stereotyped Behavior; Sympatholytics; Tegmentum Mesencephali	1999
Neurotransmitter interactions in schizophrenia-therapeutic implications. European archives of psychiatry and clinical neuroscience, 1999, Volume: 249 Suppl 4 Topics: Brain; Dopamine; Dopamine Agents; Glutamic Acid; Humans; N-Methylaspartate; Neuroprotective Agents; Receptors, GABA; Schizophrenia; Synaptic Transmission	1999
Bilateral blockade of NMDA receptors in anterior thalamus by dizocilpine (MK-801) injures pyramidal neurons in rat retrosplenial cortex. The European journal of neuroscience, 2000, Volume: 12, Issue:4 Topics: Animals; Anterior Thalamic Nuclei; Baclofen; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; HSP70 Heat-Shock Proteins; Muscimol; Nerve Degeneration; Neural Pathways; Phytohemagglutinins; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2000
Neuroleptics ameliorate phencyclidine-induced impairments of short-term memory. British journal of pharmacology, 2000, Volume: 130, Issue:1 Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Interneurons; Male; Memory Disorders; Memory, Short-Term; Phencyclidine; Rats; Risperidone; Schizophrenia; Spiperone	2000
Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies. Psychiatry research, 2000, May-15, Volume: 98, Issue:3 Topics: Adult; Aspartic Acid; Case-Control Studies; Dominance, Cerebral; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia	2000
Dopamine release in the nucleus accumbens and latent inhibition in the rat following microinjections of a 5-HT1B agonist into the dorsal subiculum: implications for schizophrenia. Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:3 Topics: Animals; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Indoles; Male; Microdialysis; Microinjections; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Schizophrenia; Serotonin; Serotonin Receptor Agonists	1998
Gene expression of PSD95 in prefrontal cortex and hippocampus in schizophrenia. Neuroreport, 2000, Sep-28, Volume: 11, Issue:14 Topics: Aged; Cerebellum; Disks Large Homolog 4 Protein; Female; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Synaptic Membranes; Synaptic Transmission	2000
Exaggerated MK-801-induced motor hyperactivity in rats with the neonatal lesion of the ventral hippocampus. Behavioural pharmacology, 2000, Volume: 11, Issue:3-4 Topics: Animals; Animals, Newborn; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Locomotion; Male; Rats; Rats, Sprague-Dawley; Schizophrenia	2000
Mutation analysis of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) in schizophrenia. Neuroscience letters, 2000, Dec-22, Volume: 296, Issue:2-3 Topics: Adult; Alleles; Brain; Brain Chemistry; DNA Mutational Analysis; Female; Genetic Testing; Genotype; Glutamic Acid; Humans; Male; Middle Aged; Mutation; Neurons; Polymorphism, Genetic; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2000
Abnormal kainate receptor expression in prefrontal cortex in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:5 Topics: Aged; Aged, 80 and over; Brain Chemistry; Female; GluK3 Kainate Receptor; Glutamic Acid; Humans; Kainic Acid; Male; Neurons; Prefrontal Cortex; Radioligand Assay; Receptors, Kainic Acid; RNA, Messenger; Schizophrenia; Tritium	2001
Regulation of sensorimotor gating in rats by hippocampal NMDA: anatomical localization. Brain research, 2001, Apr-20, Volume: 898, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia	2001
Therapeutic benefit of adjunctive dipyridamole in schizophrenia is probably due to adenosine-glutamate interactions. Journal of clinical pharmacy and therapeutics, 2001, Volume: 26, Issue:2 Topics: Adenosine; Dipyridamole; Glutamic Acid; Humans; Phosphodiesterase Inhibitors; Receptors, Dopamine D2; Schizophrenia	2001
Vesicular glutamate transporter transcript expression in the thalamus in schizophrenia. Neuroreport, 2001, Sep-17, Volume: 12, Issue:13 Topics: Aged; Carrier Proteins; Female; Gene Expression; Glutamic Acid; Humans; Male; Membrane Transport Proteins; RNA, Messenger; Schizophrenia; Synapses; Thalamus; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins	2001
Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport, 2001, Sep-17, Volume: 12, Issue:13 Topics: Bipolar Disorder; Depression; Down-Regulation; Female; Functional Laterality; Glutamic Acid; Hippocampus; Humans; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Sex Characteristics	2001
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neuroscience letters, 2001, Nov-02, Volume: 313, Issue:1-2 Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Glutamic Acid; Humans; Kynurenic Acid; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2001
Modulation of brain and serum glutamatergic concentrations following a switch from conventional neuroleptics to olanzapine. Biological psychiatry, 2002, Mar-15, Volume: 51, Issue:6 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Treatment Outcome	2002
Is NMDA receptor hypofunction in schizophrenia associated with a primary hyperglutamatergic state? Archives of general psychiatry, 2002, Volume: 59, Issue:5 Topics: Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ketamine; Lamotrigine; Models, Biological; Neurons; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission; Triazines	2002
Effect of olanzapine on glutamate levels in cerebrospinal fluid of patients with schizophrenia. Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:3 Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Glutamic Acid; Humans; Male; Olanzapine; Pirenzepine; Schizophrenia	2002
Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. The American journal of psychiatry, 2002, Volume: 159, Issue:7 Topics: Age Factors; Aged; Citrate (si)-Synthase; Female; Functional Laterality; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glutaminase; Humans; Male; Postmortem Changes; Prefrontal Cortex; Schizophrenia; Synaptic Transmission	2002
Regionally selective deficits in uptake sites for glutamate and gamma-aminobutyric acid in the basal ganglia in schizophrenia. Psychiatry research, 1992, Volume: 42, Issue:3 Topics: Aspartic Acid; Brain; Caudate Nucleus; Dominance, Cerebral; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glutamic Acid; Humans; Nipecotic Acids; Nucleus Accumbens; Proline; Putamen; Radioligand Assay; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia; Schizophrenic Psychology	1992
Evidence of glutamatergic deficiency in schizophrenia. Neuroscience letters, 1991, Jan-02, Volume: 121, Issue:1-2 Topics: Aged; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Haloperidol; Humans; In Vitro Techniques; Male; Middle Aged; Schizophrenia; Synaptosomes; Veratridine	1991
Deficient NMDA-mediated glutamate release from synaptosomes of schizophrenics. Biological psychiatry, 1991, Dec-15, Volume: 30, Issue:12 Topics: Brain; Culture Techniques; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Male; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Schizophrenia; Schizophrenic Psychology; Synaptosomes; Temporal Lobe	1991
Hyperinnervation of orbital frontal cortex in schizophrenia. The British journal of psychiatry : the journal of mental science, 1990, Volume: 157 Topics: Frontal Lobe; Glutamates; Glutamic Acid; Humans; Neurocognitive Disorders; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia; Synapses	1990
[The neurochemistry of schizophrenia]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1989, Volume: 91, Issue:8 Topics: Adult; Aged; Brain; Choline O-Acetyltransferase; Enkephalin, Methionine; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia; Substance P; Tyrosine 3-Monooxygenase	1989
Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. Journal of neurochemistry, 1989, Volume: 52, Issue:6 Topics: Aspartic Acid; Dopamine; Frontal Lobe; Glutamates; Glutamic Acid; Humans; Schizophrenia; Temporal Lobe	1989
Interactions of cholecystokinin and dopamine in the nucleus accumbens. Annals of the New York Academy of Sciences, 1985, Volume: 448 Topics: Animals; Cholecystokinin; Dopamine; Glutamates; Glutamic Acid; Humans; Nucleus Accumbens; Perfusion; Potassium; Proglumide; Receptors, Dopamine; Schizophrenia; Septal Nuclei	1985
Cerebrospinal fluid amino acid concentrations in chronic schizophrenia. Psychiatry research, 1987, Volume: 20, Issue:4 Topics: Adult; Aged; Alanine; Amino Acids; Chronic Disease; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Schizophrenia; Taurine	1987
Non-competitive regulation of phencyclidine/sigma-receptors by the N-methyl-D-aspartate receptor antagonist D-(-)-2-amino-5-phosphonovaleric acid. Neuroscience letters, 1987, Jul-22, Volume: 78, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Glutamates; Glutamic Acid; Humans; Male; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Schizophrenia; Valine	1987
Asymmetrical loss of glutamate receptor subtype in left hippocampus in schizophrenia. Lancet (London, England), 1988, Mar-12, Volume: 1, Issue:8585 Topics: Aged; Aged, 80 and over; Glutamates; Glutamic Acid; Hippocampus; Humans; Middle Aged; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Schizophrenia	1988