glutamic acid has been researched along with Rett Syndrome in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 15 (57.69) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Alt, J; Blue, ME; Fowler, A; Kannan, RM; Kannan, S; Khoury, ES; Rais, R; Ramireddy, RR; Sharma, A; Slusher, B; Thomas, AG; Tsukamoto, T | 1 |
| de Bari, L; De Filippis, B; Lacivita, E; Laviola, G; Leopoldo, M; Vacca, RA; Valenti, D; Vigli, D | 1 |
| Blue, ME; Johnston, MV; Kambhampati, SP; Kannan, RM; Kannan, S; Nance, E; Singh, S; Smith, ES; Zhang, F; Zhang, Z | 1 |
| Balakrishnan, S; Mironov, SL | 2 |
| Berry-Kravis, E; Condon, S; Della Pasqua, O; Glass, L; Glaze, DG; Jones, NE; Kaufmann, WE; Neul, JL; Oosterholt, S; Percy, AK; Stoms, G | 1 |
| Bissonnette, JM; Hunnicutt, BJ; Knopp, SJ; Levitt, ES; Williams, JT | 1 |
| El-Khoury, R; Ghata, A; Matagne, V; Panayotis, N; Roux, JC; Villard, L | 1 |
| Gao, M; Jentarra, G; Jin, Y; Li, GH; Ma, LY; Narayanan, V; Shen, JX; Turner, D; Wu, C; Wu, J; Zhang, SJ | 1 |
| Cui, N; Jiang, C; Johnson, CM; Oginsky, MF; Zhong, W | 1 |
| Cortopassi, GA; Erickson, JD; Horiuchi, M; Jin, LW; Liu, XB; Maezawa, I; Wulff, H | 1 |
| Bedogni, F; Cobolli Gigli, C; Kilstrup-Nielsen, C; Landsberger, N; Matteoli, M; Pagani, M; Pozzi, D; Rossetti, G; Rossi, RL; Scaramuzza, L | 1 |
| Berger-Sweeney, JE; Kolodny, NH; Nag, N; Ward, BC | 1 |
| Barker, PB; Bibat, G; Farage, L; Horská, A; Kaufmann, WE; Nagae, LM; Naidu, S | 1 |
| Jin, LW; Maezawa, I | 1 |
| Ellis, J; Eubanks, JH; Farra, N; Pasceri, P; Salter, MW; Zhang, WB | 1 |
| Kosai, K; Matsuishi, T; Mitsumasu, C; Okabe, Y; Takahashi, T; Tanaka, E | 1 |
| Bachi, A; Brambilla, D; Broccoli, V; Giarda, E; Hambrock, M; Kalscheuer, VM; Kilstrup-Nielsen, C; Magagnotti, C; Rademacher, N; Ricciardi, S; Sala, C; Sessa, A; Stefanelli, G; Ungaro, F; Verpelli, C | 1 |
| Blue, ME; Johnston, MV; Mullaney, B | 1 |
| Riikonen, R | 1 |
| Brendel, C; Dutschmann, M; Gärtner, J; Huppke, P; Richter, DW; Stettner, GM | 1 |
| Eubanks, JH; He, J; Jugloff, DG; Zhang, L | 1 |
| Lappalainen, R; Riikonen, RS | 1 |
| Hetherington, H; Lane, JB; Pan, JW; Percy, AK | 1 |
| Gillberg, C; Hagberg, B; Hamberger, A; Palm, A | 1 |
1 review(s) available for glutamic acid and Rett Syndrome
| Article | Year |
|---|---|
Neurobiology of Rett syndrome.
Topics: Animals; Basal Nucleus of Meynert; Brain; Cerebellum; Cerebral Cortex; Cholinergic Fibers; Chromosomal Proteins, Non-Histone; Dendrites; DNA-Binding Proteins; Glutamic Acid; Humans; Immunohistochemistry; Methyl-CpG-Binding Protein 2; Presynaptic Terminals; Purkinje Cells; Receptors, Glutamate; Repressor Proteins; Rett Syndrome; Rodentia; Synapses | 2003 |
1 trial(s) available for glutamic acid and Rett Syndrome
| Article | Year |
|---|---|
Double-blind, randomized, placebo-controlled study of trofinetide in pediatric Rett syndrome.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Double-Blind Method; Female; Glutamates; Glutamic Acid; Humans; Rett Syndrome; Treatment Outcome | 2019 |
24 other study(ies) available for glutamic acid and Rett Syndrome
| Article | Year |
|---|---|
Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome.
Topics: Animals; Dendrimers; Disease Models, Animal; Female; Glutamic Acid; Glutaminase; Glutamine; Male; Mice; Mice, Knockout; Microglia; Neuroglia; Neuroimmunomodulation; Oxidative Stress; Rett Syndrome | 2020 |
Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome.
Topics: Adenosine Triphosphate; Animals; Brain; Disease Models, Animal; Female; Glucosephosphate Dehydrogenase; Glutamic Acid; Histocompatibility Antigens; Horseradish Peroxidase; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Diseases; NADP; Piperazines; Reactive Oxygen Species; Receptors, Serotonin; Rett Syndrome; Serotonin Receptor Agonists; Superoxide Dismutase | 2017 |
Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome.
Topics: Acetylcysteine; Animals; Brain; Cytokines; Dendrimers; Disease Models, Animal; Free Radical Scavengers; Gene Expression Regulation; Glutamic Acid; Glutathione; Lipopolysaccharides; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mutation; Rett Syndrome; Tissue Distribution | 2017 |
Rescue of hyperexcitability in hippocampal CA1 neurons from Mecp2 (-/y) mouse through surface potential neutralization.
Topics: Action Potentials; Animals; Biomarkers; CA1 Region, Hippocampal; Extracellular Space; Glutamic Acid; Hydrogen-Ion Concentration; Magnesium; Methyl-CpG-Binding Protein 2; Mice; Molecular Imaging; Pyramidal Cells; Rett Syndrome; Synaptic Potentials | 2018 |
Regenerative glutamate release in the hippocampus of Rett syndrome model mice.
Topics: Action Potentials; Animals; Calcium Channels; Disease Models, Animal; Gene Knockout Techniques; Glutamic Acid; Hippocampus; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Methyl-CpG-Binding Protein 2; Mice; Neurons; Rett Syndrome | 2018 |
A selective 5-HT1a receptor agonist improves respiration in a mouse model of Rett syndrome.
Topics: Action Potentials; Animals; Apnea; Brain; Disease Models, Animal; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Piperidines; Potassium; Pyrimidines; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Respiration; Rett Syndrome; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Synaptic Transmission | 2013 |
GABA and glutamate pathways are spatially and developmentally affected in the brain of Mecp2-deficient mice.
Topics: Animals; Blotting, Western; Brain; Cells, Cultured; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamic Acid; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Nipecotic Acids; Real-Time Polymerase Chain Reaction; Rett Syndrome; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Synaptic Transmission; Tiagabine | 2014 |
Electrophysiological phenotypes of MeCP2 A140V mutant mouse model.
Topics: Action Potentials; Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Membrane Potentials; Methyl-CpG-Binding Protein 2; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neuronal Plasticity; Patch-Clamp Techniques; Phenotype; Rett Syndrome; Synaptic Transmission; Tissue Culture Techniques | 2014 |
Alterations in the cholinergic system of brain stem neurons in a mouse model of Rett syndrome.
Topics: Acetylcholine; Adaptation, Physiological; Animals; Cholinergic Neurons; Disease Models, Animal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Kinetics; Locus Coeruleus; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, Nicotinic; Receptors, Presynaptic; Rett Syndrome | 2014 |
Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity.
Topics: Adenosine Triphosphate; Amino Acid Transport System A; Animals; Glutamic Acid; Glycine; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Mitochondrial Diseases; Neurotoxicity Syndromes; Oxygen Consumption; Primary Cell Culture; Rett Syndrome | 2015 |
Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.
Topics: Animals; Calcium; Cell Movement; Cells, Cultured; Cerebral Cortex; Disease Progression; Electric Stimulation; Fluorescent Antibody Technique; Glutamic Acid; Methyl-CpG-Binding Protein 2; Mice, Knockout; Neurons; Rett Syndrome; Time Factors; Transcription, Genetic; Voltage-Sensitive Dye Imaging | 2016 |
Neurochemical changes in a mouse model of Rett syndrome: changes over time and in response to perinatal choline nutritional supplementation.
Topics: Age Factors; Animals; Animals, Newborn; Aspartic Acid; Brain; Choline; Creatine; Dietary Supplements; Disease Models, Animal; DNA-Binding Proteins; Glutamic Acid; Glutamine; Histone Deacetylases; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Nootropic Agents; Rett Syndrome; Spectrum Analysis | 2009 |
Brain metabolism in Rett syndrome: age, clinical, and genotype correlations.
Topics: Adolescent; Aging; Analysis of Variance; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Female; Frontal Lobe; Genotype; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Magnetic Resonance Spectroscopy; Methyl-CpG-Binding Protein 2; Mutation; Protons; Rett Syndrome; Severity of Illness Index | 2009 |
Rare diseases offer insights into autism spectrum disorders. Preliminary laboratory studies suggest new biological targets for intervention.
Topics: Animals; Autistic Disorder; Drosophila; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glutamic Acid; Humans; Immunosuppressive Agents; Methyl-CpG-Binding Protein 2; Mice; Protein Kinases; Rett Syndrome; Sirolimus; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2009 |
Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Connexins; Culture Media, Conditioned; Dendrites; Disease Models, Animal; Gap Junction beta-1 Protein; Glutamic Acid; Glutaminase; Hippocampus; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Neurons; Receptors, Glutamate; Rett Syndrome; Synapses | 2010 |
Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations.
Topics: Action Potentials; Animals; Cell Differentiation; Cell Line; Disease Models, Animal; Glutamic Acid; Induced Pluripotent Stem Cells; Methyl-CpG-Binding Protein 2; Mice; Mice, Mutant Strains; Miniature Postsynaptic Potentials; Neurons; Phenotype; Rett Syndrome; Synaptic Transmission | 2012 |
Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Brain; Cells, Cultured; Gene Expression; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Methyl-CpG-Binding Protein 2; Mice; Mice, Knockout; Nerve Growth Factors; Neurons; Rett Syndrome; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2012 |
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.
Topics: Amino Acid Sequence; Animals; Cell Adhesion; Cells, Cultured; Chlorocebus aethiops; COS Cells; Dendritic Spines; Disks Large Homolog 4 Protein; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Cell Surface; Rett Syndrome; Spine; Synapses | 2012 |
Neurotrophic factors in the pathogenesis of Rett syndrome.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acids; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Humans; Infant; Insulin-Like Growth Factor I; Nerve Growth Factor; Nerve Growth Factors; Rett Syndrome | 2003 |
Breathing dysfunctions associated with impaired control of postinspiratory activity in Mecp2-/y knockout mice.
Topics: Animals; Electric Stimulation; Exhalation; Genotype; Glutamic Acid; Inhalation; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Phenotype; Pons; Respiratory Insufficiency; Rett Syndrome; Vagus Nerve; X Chromosome | 2007 |
The MeCP2-null mouse hippocampus displays altered basal inhibitory rhythms and is prone to hyperexcitability.
Topics: Action Potentials; Animals; Biological Clocks; Cortical Synchronization; DNA-Binding Proteins; Electric Stimulation; Female; Glutamic Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Knockout; Nerve Net; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Periodicity; Rett Syndrome; Synaptic Transmission | 2008 |
High levels of cerebrospinal fluid glutamate in Rett syndrome.
Topics: Adolescent; Amino Acids; Aspartic Acid; Child; Child, Preschool; Female; Glutamic Acid; Humans; Infant; Rett Syndrome | 1996 |
Rett syndrome: 1H spectroscopic imaging at 4.1 Tesla.
Topics: Aspartic Acid; Brain; Child; Child, Preschool; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Reference Values; Rett Syndrome | 1999 |
Elevated CSF glutamate in Rett syndrome.
Topics: Adult; Amino Acids; Autistic Disorder; Child; Diagnosis, Differential; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Humans; Rett Syndrome | 1992 |