Compounds > glutamic acid

glutamic acid and Retinal Degeneration

glutamic acid has been researched along with Retinal Degeneration in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19908 (14.55)18.7374
1990's5 (9.09)18.2507
2000's21 (38.18)29.6817
2010's17 (30.91)24.3611
2020's4 (7.27)2.80

Authors

AuthorsStudies
Bansal, PK; Guo, H; Morgan, JI; Rong, Y; Wei, P; Wu, HY1
Aldana, BI; Bergersen, LH; Freude, KK; Hannibal, J; Kolko, M; Mouhammad, ZA; Sanz-Morello, B; Tams, ALM; Vohra, R1
Arai, S; Gonome, T; Kudo, T; Maeda-Monai, N; Nakazawa, M; Tanabu, R; Xie, Y; Yamauchi, K1
Augustin, S; Barmo, N; Beguier, F; Blot, G; Charles-Messance, H; Couturier, A; Forster, V; Grosche, A; Guillonneau, X; Picaud, S; Rendon, A; Sahel, JA; Sennlaub, F; Siqueiros, L; Tadayoni, R; Touhami, S; Vignaud, L1
Ai, LQ; Chen, C; Gao, L; Lin, S; Liu, W; Xiao, H; Ye, J; Zhou, Y1
Rountree, CM; Saggere, L; Troy, JB2
Ivanova, E; Sagdullaev, BT; Toychiev, AH; Willis, DE; Yee, CW1
Allemandi, DA; Carpentieri, AR; de Barboza, GED; Del Valle Bessone, C; Fajreldines, HD; Quinteros, DA; Tolosa de Talamoni, NG1
Liu, K; Wang, Y; Weng, C; Yin, Z; Zeng, Y1
Guo, X; Harada, C; Harada, T; Kawamura, K; Kimura, A; Namekata, K; Tanaka, K1
Adler, L; Chen, C; Koutalos, Y1
Ju, WK; Kim, H; Kim, KY; Kim, SY; Lee, D; Noh, YH; Shim, MS; Weinreb, RN1
Bagg, EE; Britt, SG; Farrell, DM; Fulton, RM; Manino, M; Salcedo, E; Zheng, L1
Bieche, I; Bosch Grau, M; Gadadhar, S; Janke, C; Marques Sousa, P; Masson, C; Rocha, C; Tort, O; Vacher, S1
Izawa, T; Kuwamura, M; Matsumoto, M; Mitori, H; Yamate, J1
Barhoum, R; Corrochano, S; Cuenca, N; de la Rosa, EJ; de la Villa, P; Fernandez-Sanchez, L; Germain, F; Martínez-Navarrete, G1
Chua, J; Fletcher, EL; Kalloniatis, M1
Ishii, K; Ishii, T; Kuroki, T; Mori, A; Nakahara, T; Sakamoto, K; Shigeta, N1
Fuse, N; Guo, X; Harada, C; Harada, T; Kikushima, K; Kimura, A; Kohyama, K; Matsumoto, Y; Mitamura, Y; Namekata, K; Tanaka, K1
Finlayson, PG; Iezzi, R1
Guo, X; Harada, C; Harada, T; Kimura, A; Nakamura, K; Namekata, K; Parada, LF; Tanaka, K1
Menzler, J; Zeck, G1
Anderson, J; Jones, BW; Kondo, M; Lin, Y; Marc, RE; Rapp, K; Shaw, MV; Terasaki, H; Watt, CB; Yang, JH1
Ishikawa, M; Izumi, Y; Yoshitomi, T; Zorumski, CF1
Goto, W; Hara, H; Kawazu, K; Miyawaki, N; Morikawa, N; Ota, T; Otori, Y; Tano, Y1
CASIMIR, J; JADOT, J; RENARD, M1
EMMRICH, R; ZIMMERMANN, S1
Sauer, MW; Starnes, CA; Winkler, BS1
Ruiz, G; Wijono, M; Woldemussie, E1
Isenoumi, K; Kitaoka, Y; Kobayashi, S; Kumai, T; Kuribayashi, K; Lam, TT; Motoki, M; Munemasa, Y; Ueno, S1
Barkis, WB; Barres, BA; Chen, S; Diamond, JS; Ullian, EM1
Machida, S; Masuda, T; Mukaida, Y; Takahashi, T; Tazawa, Y1
Biedermann, B; Bringmann, A; Iandiev, I; Pannicke, T; Reichel, MB; Reichenbach, A1
Delyfer, MN; Léveillard, T; Neveux, N; Sahel, JA; Simonutti, M1
Delyfer, MN; Forster, V; Léveillard, T; Neveux, N; Picaud, S; Sahel, JA1
Atlasz, T; Babai, N; Gábriel, R; Kiss, P; Reglödi, D; Tamás, A; Tóth, G1
Bottrell, AR; Dang, L; Fariss, RN; Goldberg, AF; Khattree, N; Peachey, NS; Ritter, LM; Yu, M1
Harada, C; Harada, T; Kohyama, K; Matsumoto, Y; Namekata, K1
Casper, DS; Reif-Lehrer, L; Trelstad, RL1
Hiraiwa, N; Inagaki, E; Ishiguro, I; Iwasaki, K; Matsuzawa, T1
Kamada, Y; Matsuda, M; Miyazaki, H; Mizuno, A; Tsuneoka, H1
Bush, RA; Hawks, KW; Sieving, PA1
Bae, JH; Chidlow, G; Melena, J; Nash, MS; Osborne, NN; Wood, JP1
Aaberg, TM1
Duda, T; Koch, KW; Krishnan, A; Lange, C; Sharma, RK; Venkataraman, V1
Fletcher, EL1
D'Anna, SA; Kerrigan, D; Kerrigan-Baumrind, LA; Levkovitch-Verbin, H; Pease, ME; Quigley, HA1
Barouch, R; Friedmann, I; Schwartz, M; Shani, Y; Yoles, E1
Callebert, J; Ferrari, P; Morice, C; Versaux-Botteri, C; Wasowicz, M1
Chorich, L; Fan, K; Moshfeghi, DM; Peachey, NS; Shugart, YY; Thirumalaichary, S; Yang, Z; Zhang, K1
Dawson, R; Sherry, DM; Ulshafer, RJ; Wallace, DR1
Olney, JW; Rothman, SM1
Jones, ME1
Labruyere, J; Olney, JW; Price, MT; Samson, L1

Reviews

3 review(s) available for glutamic acid and Retinal Degeneration

ArticleYear
Ganglion cell death in glaucoma: what do we really know?
    The British journal of ophthalmology, 1999, Volume: 83, Issue:8

    Topics: Apoptosis; Axons; Cell Death; Ganglia, Sensory; Glaucoma; Glutamic Acid; Humans; Receptors, Cell Surface; Retinal Degeneration; Vitreous Body

1999
Alterations in neurochemistry during retinal degeneration.
    Microscopy research and technique, 2000, Jul-15, Volume: 50, Issue:2

    Topics: Animals; Animals, Newborn; Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Immunohistochemistry; Neurotransmitter Agents; Photoreceptor Cells, Vertebrate; Rats; Retina; Retinal Degeneration; Retinitis Pigmentosa; Time Factors

2000
Glutamate and the pathophysiology of hypoxic--ischemic brain damage.
    Annals of neurology, 1986, Volume: 19, Issue:2

    Topics: Animals; Baclofen; Brain; Brain Ischemia; Calcium Channel Blockers; Cats; Cells, Cultured; Cerebral Cortex; Cortical Spreading Depression; Dipeptides; Glutamates; Glutamic Acid; Hippocampus; Hypothalamic Diseases; Hypoxia, Brain; Ion Channels; Mice; Rabbits; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Retinal Degeneration; Synaptic Transmission

1986

Other Studies

52 other study(ies) available for glutamic acid and Retinal Degeneration

ArticleYear
TTLL1 and TTLL4 polyglutamylases are required for the neurodegenerative phenotypes in pcd mice.
    PLoS genetics, 2022, Volume: 18, Issue:4

    Topics: Animals; Glutamic Acid; GTP-Binding Proteins; Male; Phenotype; Purkinje Cells; Retinal Degeneration; Rhodopsin

2022
Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants.
    Cells, 2022, 07-02, Volume: 11, Issue:13

    Topics: Adenosine Triphosphate; Animals; Cell Death; Glutamic Acid; Lactic Acid; Mice; Nitric Oxide; Receptors, G-Protein-Coupled; Retinal Degeneration

2022
Excess Glutamate May Cause Dilation of Retinal Blood Vessels in Glutamate/Aspartate Transporter-Deficient Mice.
    BioMed research international, 2019, Volume: 2019

    Topics: Amino Acid Transport System X-AG; Animals; Disease Models, Animal; Electroretinography; Fundus Oculi; Glutamic Acid; Humans; Mice; Mice, Knockout; Photoreceptor Cells, Vertebrate; Retina; Retinal Degeneration; Retinal Vessels; Tomography, Optical Coherence

2019
IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis.
    Journal of neuroinflammation, 2020, Jan-03, Volume: 17, Issue:1

    Topics: Animals; Coculture Techniques; Glutamic Acid; Homeostasis; Humans; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocytes; Retinal Degeneration; Retinal Rod Photoreceptor Cells

2020
Vps35 Deficiency Impairs Cdk5/p35 Degradation and Promotes the Hyperphosphorylation of Tau Protein in Retinal Ganglion Cells.
    Investigative ophthalmology & visual science, 2020, Jan-23, Volume: 61, Issue:1

    Topics: Animals; Blotting, Western; Cells, Cultured; Cyclin-Dependent Kinase 5; Down-Regulation; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Lysosomal Membrane Proteins; Male; Mice; Phosphorylation; Phosphotransferases; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Retinal Degeneration; Retinal Ganglion Cells; Roscovitine; tau Proteins; Transfection; Ubiquitin-Activating Enzymes; Vesicular Transport Proteins

2020
Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro.
    Journal of visualized experiments : JoVE, 2017, 12-19, Issue:130

    Topics: Animals; Biomimetics; Glutamic Acid; Humans; Neurotransmitter Agents; Photoreceptor Cells; Photoreceptor Cells, Vertebrate; Rats; Rats, Long-Evans; Retina; Retinal Degeneration

2017
Microfluidics-Based Subretinal Chemical Neuromodulation of Photoreceptor Degenerated Retinas.
    Investigative ophthalmology & visual science, 2018, 01-01, Volume: 59, Issue:1

    Topics: Action Potentials; Animals; Biomimetics; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Male; Microfluidics; Neurotransmitter Agents; Photic Stimulation; Rats; Rats, Long-Evans; Rats, Transgenic; Retinal Degeneration; Retinal Ganglion Cells; Tissue Array Analysis

2018
Atypical Expression and Activation of GluN2A- and GluN2B-Containing NMDA Receptors at Ganglion Cells during Retinal Degeneration.
    Neuroscience, 2018, 11-21, Volume: 393

    Topics: Animals; Excitatory Postsynaptic Potentials; Ganglia, Invertebrate; Glutamic Acid; Mice; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Degeneration; Retinal Ganglion Cells; Synapses

2018
Protective role of melatonin on retinal ganglionar cell: In vitro an in vivo evidences.
    Life sciences, 2019, Feb-01, Volume: 218

    Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Chick Embryo; Glutamic Acid; In Vitro Techniques; Melatonin; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Rabbits; Retinal Degeneration; Retinal Ganglion Cells

2019
Changes in glutamate homeostasis cause retinal degeneration in Royal College of Surgeons rats.
    International journal of molecular medicine, 2013, Volume: 31, Issue:5

    Topics: Animals; Biological Transport; Blotting, Western; Densitometry; Excitatory Amino Acid Transporter 1; Fluorescent Antibody Technique; Glutamate-Ammonia Ligase; Glutamic Acid; Homeostasis; Protein Kinase C-alpha; Rats; Retinal Degeneration; RNA, Messenger; Vesicular Glutamate Transport Protein 1

2013
Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma.
    Cell death and differentiation, 2013, Volume: 20, Issue:9

    Topics: Animals; Apoptosis; Binding Sites; Carrier Proteins; Cell Line; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Glutamic Acid; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Low Tension Glaucoma; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Oxidative Stress; Phosphorylation; Protein Binding; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Degeneration; Retinal Ganglion Cells; Signal Transduction

2013
Mitochondria contribute to NADPH generation in mouse rod photoreceptors.
    The Journal of biological chemistry, 2014, Jan-17, Volume: 289, Issue:3

    Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Glutamic Acid; Mice; Mice, Knockout; Mitochondria; NADP; Pyruvic Acid; Retinal Degeneration; Retinal Rod Photoreceptor Cells

2014
Coenzyme Q10 inhibits glutamate excitotoxicity and oxidative stress-mediated mitochondrial alteration in a mouse model of glaucoma.
    Investigative ophthalmology & visual science, 2014, Feb-18, Volume: 55, Issue:2

    Topics: Animals; Axons; bcl-Associated Death Protein; Blotting, Western; Disease Models, Animal; Female; Glaucoma; Glial Fibrillary Acidic Protein; Glutamic Acid; Heme Oxygenase-1; In Situ Nick-End Labeling; Membrane Proteins; Mice; Mice, Inbred DBA; Mitochondria; Nerve Tissue Proteins; Oxidative Stress; Real-Time Polymerase Chain Reaction; Receptors, N-Methyl-D-Aspartate; Retinal Degeneration; Retinal Ganglion Cells; Superoxide Dismutase; Ubiquinone; Vitamins

2014
Analysis of Conserved Glutamate and Aspartate Residues in Drosophila Rhodopsin 1 and Their Influence on Spectral Tuning.
    The Journal of biological chemistry, 2015, Sep-04, Volume: 290, Issue:36

    Topics: Animals; Aspartic Acid; Blotting, Western; Conserved Sequence; Drosophila melanogaster; Drosophila Proteins; Glutamic Acid; Microspectrophotometry; Mutation; Opsins; Phylogeny; Protein Structure, Secondary; Retinal Degeneration; Rhodopsin

2015
Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.
    Journal of cell science, 2017, 03-01, Volume: 130, Issue:5

    Topics: Animals; Apoptosis; Cilia; Glutamic Acid; Glycosylation; Mice, Inbred C57BL; Neuroglia; Peptide Synthases; Phenotype; Photoreceptor Cells, Vertebrate; Purkinje Cells; Retina; Retinal Degeneration; Rhodopsin; Time Factors; Tubulin

2017
Developing Stage-dependent Retinal Toxicity Induced by l-glutamate in Neonatal Rats.
    Toxicologic pathology, 2016, Volume: 44, Issue:8

    Topics: Animals; Animals, Newborn; Apoptosis; Glutamic Acid; Injections, Subcutaneous; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Retinal Photoreceptor Cell Inner Segment

2016
Functional and structural modifications during retinal degeneration in the rd10 mouse.
    Neuroscience, 2008, Aug-26, Volume: 155, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Cell Death; Disease Models, Animal; Electroretinography; Glutamic Acid; In Situ Nick-End Labeling; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nerve Tissue Proteins; Retina; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Time Factors

2008
Functional remodeling of glutamate receptors by inner retinal neurons occurs from an early stage of retinal degeneration.
    The Journal of comparative neurology, 2009, Jun-10, Volume: 514, Issue:5

    Topics: Agmatine; Animals; Calbindin 2; Cell Count; Glutamic Acid; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Confocal; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retinal Degeneration; Retinal Neurons; Retinitis Pigmentosa; S100 Calcium Binding Protein G; Synapses; Vesicular Glutamate Transport Protein 1

2009
The prostanoid EP(2) receptor agonist ONO-AE1-259-01 protects against glutamate-induced neurotoxicity in rat retina.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Animals; Cell Count; Dinoprostone; Glutamic Acid; Injections; Male; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Retina; Retinal Degeneration; Retinal Ganglion Cells

2009
Interleukin-1 attenuates normal tension glaucoma-like retinal degeneration in EAAC1-deficient mice.
    Neuroscience letters, 2009, Nov-13, Volume: 465, Issue:2

    Topics: Animals; Cell Death; Cell Survival; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Glaucoma; Glutamic Acid; Interleukin-1; Intracellular Space; Intraocular Pressure; Mice; Mice, Knockout; Neuroglia; Retina; Retinal Degeneration; Retinal Ganglion Cells; Sodium

2009
Glutamate stimulation of retinal ganglion cells in normal and s334ter-4 rat retinas: a candidate for a neurotransmitter-based retinal prosthesis.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:7

    Topics: Action Potentials; Animals; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Photic Stimulation; Photoreceptor Cells, Vertebrate; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Ganglion Cells

2010
Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration.
    Nature communications, 2011, Feb-08, Volume: 2

    Topics: Animals; beta-Galactosidase; Brain-Derived Neurotrophic Factor; Cells, Cultured; Glutamic Acid; Immunoblotting; Immunohistochemistry; Mice; Mice, Knockout; Neuroglia; Neurons; Receptor, trkB; Regeneration; Retinal Degeneration; Signal Transduction

2011
Network oscillations in rod-degenerated mouse retinas.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-09, Volume: 31, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Carbenoxolone; Cyclooxygenase Inhibitors; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Glycine; In Vitro Techniques; Light; Male; Meclofenamic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Net; Neural Inhibition; Periodicity; Pyridazines; Quinoxalines; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Sodium Channel Blockers; Statistics as Topic; Tetrodotoxin

2011
Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration.
    The Journal of comparative neurology, 2011, Oct-01, Volume: 519, Issue:14

    Topics: Adult; Animals; Animals, Genetically Modified; Disease Models, Animal; Disease Progression; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Opsins; Rabbits; Retina; Retinal Degeneration; Retinitis Pigmentosa; Taurine

2011
Downregulation of glutamine synthetase via GLAST suppression induces retinal axonal swelling in a rat ex vivo hydrostatic pressure model.
    Investigative ophthalmology & visual science, 2011, Aug-22, Volume: 52, Issue:9

    Topics: Animals; Aspartic Acid; Axons; Blotting, Western; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Fluorescent Antibody Technique, Indirect; Glutamate-Ammonia Ligase; Glutamic Acid; Hydrostatic Pressure; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2011
Protective effects of timolol against the neuronal damage induced by glutamate and ischemia in the rat retina.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Action Potentials; Acute Disease; Animals; Cell Death; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Excitatory Amino Acid Antagonists; Fetus; Glaucoma; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Retinal Degeneration; Retinal Ganglion Cells; Timolol

2002
[Separation and characterization of the L-gamma-(p-hydroxy)-anilide of glutamic acid from Agaricus hortensis].
    Biochimica et biophysica acta, 1960, Sep-23, Volume: 43

    Topics: Agaricales; Agaricus; Anilides; Gamma Rays; Glutamates; Glutamic Acid; Retinal Degeneration

1960
[On the behavior of glutamic acid transaminase in the electrophoretic separation of serum proteins].
    Klinische Wochenschrift, 1959, Sep-01, Volume: 37

    Topics: Blood Proteins; Electrophoresis; Glutamic Acid; Retinal Degeneration; Retinal Detachment; Transaminases

1959
Effects of L-glutamate/D-aspartate and monensin on lactic acid production in retina and cultured retinal Müller cells.
    Journal of neurochemistry, 2004, Volume: 89, Issue:2

    Topics: Animals; Antimycin A; Cells, Cultured; D-Aspartic Acid; Enzyme Inhibitors; Glutamic Acid; Ionophores; Lactic Acid; Monensin; Neuroglia; Ouabain; Rats; Rats, Mutant Strains; Retina; Retinal Degeneration; Sodium

2004
Müller cell response to laser-induced increase in intraocular pressure in rats.
    Glia, 2004, Aug-01, Volume: 47, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Cell Count; Disease Models, Animal; Down-Regulation; Glaucoma; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Homeostasis; Intraocular Pressure; Lasers; Male; Neuroglia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reaction Time; Retina; Retinal Degeneration; Retinal Ganglion Cells

2004
Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retina.
    Brain research, 2004, Aug-20, Volume: 1018, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Count; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Degeneration; Retinal Ganglion Cells; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Thy-1 Antigens; Up-Regulation

2004
Invulnerability of retinal ganglion cells to NMDA excitotoxicity.
    Molecular and cellular neurosciences, 2004, Volume: 26, Issue:4

    Topics: Amacrine Cells; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Fluorescent Dyes; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate; Retinal Degeneration; Retinal Ganglion Cells; Stilbamidines; Synaptic Transmission

2004
Functional changes in rod and cone pathways after photoreceptor loss in light-damaged rats.
    Current eye research, 2005, Volume: 30, Issue:8

    Topics: Animals; Cell Count; Cell Death; Electroretinography; Glutamic Acid; Interneurons; Light; Male; Photoreceptor Cells, Vertebrate; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Visual Pathways; Vitreous Body

2005
Atypical gliosis in Müller cells of the slowly degenerating rds mutant mouse retina.
    Experimental eye research, 2006, Volume: 82, Issue:3

    Topics: Animals; Biomarkers; Electrophysiology; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Retina; Retinal Degeneration; Sodium Channels; Time Factors

2006
Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?
    Molecular vision, 2005, Sep-01, Volume: 11

    Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glutamic Acid; Glutamine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Confocal; Neuroprotective Agents; Organ Culture Techniques; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina.
    Molecular vision, 2005, Sep-01, Volume: 11

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Blotting, Western; Cell Survival; Chromatography, Ion Exchange; Electroretinography; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Injections, Intraperitoneal; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vimentin

2005
Degree of damage compensation by various PACAP treatments in monosodium glutamate-induced retinal degeneration.
    Neurotoxicity research, 2005, Volume: 8, Issue:3-4

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Glutamic Acid; Male; Neuroprotective Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Retinal Degeneration; Time Factors

2005
An intramembrane glutamic acid governs peripherin/rds function for photoreceptor disk morphogenesis.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:7

    Topics: Amino Acid Substitution; Animals; Blotting, Western; Chlorocebus aethiops; COS Cells; Electroretinography; Gene Expression Regulation; Genotype; Glutamic Acid; Immunoprecipitation; Intermediate Filament Proteins; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Morphogenesis; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Peripherins; Photoreceptor Cells, Vertebrate; Retina; Retinal Degeneration; Transgenes

2007
Interleukin-1 stimulates glutamate uptake in glial cells by accelerating membrane trafficking of Na+/K+-ATPase via actin depolymerization.
    Molecular and cellular biology, 2008, Volume: 28, Issue:10

    Topics: Actins; Animals; Base Sequence; Biological Transport, Active; Caspase Inhibitors; Caspases; Caspases, Initiator; Cells, Cultured; Glutamic Acid; Interleukin-1; Mice; Mice, Inbred C57BL; Neuroglia; Receptors, Interleukin-1; Retina; Retinal Degeneration; Retinal Ganglion Cells; RNA Interference; Sodium; Sodium-Potassium-Exchanging ATPase

2008
Glutamate-induced cellular injury in isolated chick embryo retina: Müller cell localization of initial effects.
    The Journal of comparative neurology, 1982, Jul-20, Volume: 209, Issue:1

    Topics: Animals; Chick Embryo; Glutamates; Glutamic Acid; In Vitro Techniques; Neuroglia; Neurons; Retina; Retinal Degeneration

1982
Disease of ornithine-proline pathway: a delta 1-pyrroline-5-carboxylate reductase deficiency in the retina or retinal degeneration mice.
    Advances in experimental medicine and biology, 1982, Volume: 153

    Topics: Animals; Arginase; Cattle; Cornea; Female; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred C3H; Ornithine; Ornithine Carbamoyltransferase; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroline Carboxylate Reductases; Retina; Retinal Degeneration

1982
Effects of glutamic acid, kainic acid and aspartic acid on GABA release from rat retina degenerated by kainic acid.
    Japanese journal of ophthalmology, 1984, Volume: 28, Issue:1

    Topics: Animals; Aspartic Acid; Depression, Chemical; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; Pyrrolidines; Rats; Retina; Retinal Degeneration; Stimulation, Chemical

1984
Preservation of inner retinal responses in the aged Royal College of Surgeons rat. Evidence against glutamate excitotoxicity in photoreceptor degeneration.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:10

    Topics: Aging; Animals; Dark Adaptation; Electroretinography; Female; Glutamic Acid; Male; Neurons; Photoreceptor Cells; Rats; Rats, Mutant Strains; Retina; Retinal Degeneration; Sensory Thresholds; Signal Transduction

1995
Does hyperoxygenation limit retinal degeneration after retinal detachment?
    American journal of ophthalmology, 1999, Volume: 128, Issue:2

    Topics: Animals; Cell Death; Cell Division; Disease Models, Animal; Fibroblast Growth Factor 2; Glutamate Synthase; Glutamic Acid; Neuroglia; Oxygen Inhalation Therapy; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Retinal Detachment

1999
Mutations in the rod outer segment membrane guanylate cyclase in a cone-rod dystrophy cause defects in calcium signaling.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Animals; Arginine; Aspartic Acid; Calcium Signaling; Calcium-Binding Proteins; Cattle; Cysteine; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Guanylate Cyclase-Activating Proteins; Humans; Mutagenesis, Insertional; Protein Binding; Receptors, Cell Surface; Retinal Degeneration; Rod Cell Outer Segment; S100 Proteins

1999
Optic nerve transection in monkeys may result in secondary degeneration of retinal ganglion cells.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:5

    Topics: Animals; Axons; Cell Count; Cell Death; Fluorescein Angiography; Glutamic Acid; Macaca fascicularis; Nerve Fibers; Optic Nerve; Optic Nerve Injuries; Retinal Degeneration; Retinal Ganglion Cells

2001
Self-Protective mechanism awakened by glutamate in retinal ganglion cells.
    Journal of neurotrauma, 2001, Volume: 18, Issue:3

    Topics: Animals; Aqueous Humor; Cell Survival; Free Radicals; Glutamic Acid; Male; Nerve Growth Factors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Ganglion Cells

2001
Long-term effects of light damage on the retina of albino and pigmented rats.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:3

    Topics: Animals; Apoptosis; Aspartic Acid; Chromatography, High Pressure Liquid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; In Situ Nick-End Labeling; Light; Longitudinal Studies; Male; Radiation Injuries, Experimental; Rats; Rats, Long-Evans; Rats, Wistar; Retina; Retinal Degeneration; Taurine; Vitreous Body

2002
Mutations in the RPGR gene cause X-linked cone dystrophy.
    Human molecular genetics, 2002, Mar-01, Volume: 11, Issue:5

    Topics: Amino Acid Sequence; Base Sequence; Carrier Proteins; Color Vision Defects; Eye Proteins; Glutamic Acid; Heterozygote; Humans; Male; Mutation; Open Reading Frames; Pedigree; Photophobia; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Sequence Deletion; Visual Fields; X Chromosome

2002
Excitatory amino acid involvement in retinal degeneration.
    Brain research, 1990, Oct-29, Volume: 531, Issue:1-2

    Topics: Animals; Aspartic Acid; Blindness; Chickens; Crosses, Genetic; Female; Glutamates; Glutamic Acid; Male; Mutation; Reference Values; Retina; Retinal Degeneration

1990
Conversion of glutamate to ornithine and proline: pyrroline-5-carboxylate, a possible modulator of arginine requirements.
    The Journal of nutrition, 1985, Volume: 115, Issue:4

    Topics: Amino Acids; Animals; Arginine; Biotransformation; Glutamates; Glutamic Acid; Humans; Intestinal Mucosa; Kidney; Liver; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Retinal Degeneration; Spleen

1985
The role of specific ions in glutamate neurotoxicity.
    Neuroscience letters, 1986, Mar-28, Volume: 65, Issue:1

    Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Drug Synergism; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Necrosis; Retinal Degeneration; Sodium

1986