glutamic acid and Necrosis

glutamic acid has been researched along with Necrosis in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (4.42)	18.7374
1990's	28 (24.78)	18.2507
2000's	53 (46.90)	29.6817
2010's	24 (21.24)	24.3611
2020's	3 (2.65)	2.80

Authors

Authors	Studies
Huang, JF; Liao, LS; Liu, SM; Wang, SC	1
Ciric, D; Foretz, M; Isakovic, A; Jovanovic, M; Korolchuk, VI; Markovic, I; Martinovic, T; Misirkic, M; Rabanal-Ruiz, Y; Saponjic, J; Trajkovic, V; Vucicevic, L	1
Idrizi, A; Mano, I; Mendelowitz, ZZ	1
Downing, S; Downing, TG; Scott, LL	1
Li, L; Robinson, HPC	1
Gooz, MA; Gudz, TI; Lemasters, JJ; Li, L; Novgorodov, SA; Voltin, JR	1
Culmsee, C; Diemert, S; Eisenbach, I; Ganjam, GK; Herden, C; Hoffmann, L; Plesnila, N; Reuther, C; Roth, J; Terpolilli, NA	1
Chen, D; Huang, J; Huang, Y; Ji, D; Liao, L; Liu, F; Wang, M; Wang, S; Wang, Z; Xia, X; Xiong, K; Yan, Y; Zhou, H	1
Bronfman, FC; Catalán, RJ; Court, FA; Hernández, DE; Moya-Alvarado, G; Salvadores, NA	1
Ahmed, T; Becker, JL; Chowdhury, A; Diaz, K; Feldmann, KG; Haider, S; Mano, I; McAlpin, N; Mehta, MG; Richard Xia, JX	1
Alvaro, AR; Ambrósio, AF; Cavadas, C; Elvas, F; Santos-Carvalho, A	1
Boćkowski, L; Dąbrowska, M; Iłendo, E; Koput, A; Rusak, M; Sendrowski, K; Sobaniec, P; Sobaniec, W	1
He, Y; Li, F; Liu, J; Liu, K; Shi, W; Wang, Z; Wei, X; Xu, H; Yang, F; Yi, F; Zhang, H; Zhang, X; Zhang, Y; Zhu, T	1
Anastassov, I; Chappell, RL; Ripps, H	1
Koh, PO	1
Aihara, M; Yamagishi, R	1
Cui, Z; Ge, D; Guan, S; Guo, Y; Liu, T; Ma, X; Xu, J	1
Bojarski, B; Budziszewska, B; Detka, J; Głombik, K; Kucharczyk, M; Kurek, A; Lasoń, W; Ludwikowska, A; Ślusarczyk, J; Trojan, E	1
Ben-Arie, G; Benifla, M; Cagnano, E; Ivens, S; Melamed, I; Merkin, V; Serlin, Y; Shelef, I	1
Florkowski, A; Gałecka, E; Gałecki, P; Mrowicka, M; Pietras, T	1
Akaike, A; Fujii, T; Izumi, Y; Kume, T; Niidome, T; Ohgi, Y; Sugimoto, H; Takada-Takatori, Y	1
Antonov, SM; Dvoretskova, EA; Evstratova, AA; Mironova, EV	2
Braz, MH; Chatterjee, S; Figueiredo, C; Pais, TF; Peixoto, R	1
Baik, EJ; Jung, YS; Kim, YS; Lee, BK; Lee, DH; Lee, KH; Lee, MG; Lee, S; Lee, SH; Moon, CH; Park, S; Park, SL; Yi, KY; Yoo, SE; Yoon, JS	1
Allen, S; Lopez-Meraz, ML; Niquet, J; Seo, DW; Wasterlain, CG	1
Choi, HJ; Choi, J; Fukui, M; Song, JH; Zhu, BT	1
Hisano, K; Morimoto, Y; Watanabe, M	1
Desfeux, A; El Ghazi, F; Gonzalez, BJ; Jégou, S; Laudenbach, V; Legros, H; Marret, S	1
Baumgartner, WA; Blue, ME; Brock, MV; Johnston, MV; Lange, MS; Lowenstein, CJ; Troncoso, JC; Tseng, EE	1
Chua, BH; Chua, CC; Geng, D; Hamdy, RC; Liu, CF; Xu, X; Zhang, M	1
Hisano, K; Hua, Y; Morimoto, Y	1
Andriessen, TM; Jacobs, B; Vos, PE	1
Crema, LM; da Rocha, ER; Dalmaz, C; de Vasconcellos-Bittencourt, AP; Frozza, R; Nassif, M; Nieto, FB; Salbego, C; Thomazi, AP; Vendite, DA; Wofchuk, S	1
Armstead, WM; Cines, DB; Higazi, AA; Riley, J; Smith, DH; Yarovoi, S	1
Li, CY; Shi, HB; Song, NY; Ye, HB; Yin, SK	1
Fujikawa, DG; Wu, A	1
Allen, NJ; Attwell, D	1
Eşrefoğlu, M; Gepdiremen, A; Kuruş, M	1
Bondada, V; Geddes, JW; Pang, Z; Sengoku, T; Siman, R	1
SCHON, H; STEIDL, E	1
Daval, JL; Grojean, S; Pourié, G; Vert, P	1
Nicholls, DG	1
Bernal, F; Fredriksson, K; Mahy, N; Ramonet, D; Rodríguez, MJ	1
Brazel, CY; Levison, SW; Nuñez, JL; Yang, Z	1
Monaco, EA; Vallano, ML	1
Andrade, AL; Attwell, D; Hamann, M; Mohr, C; Rossi, DJ	1
Brites, D; Brito, MA; Falcão, AS; Fernandes, A; Silva, RF	1
Auberson, YP; DeRidder, MN; Meaney, DF; Raghupathi, R; Siman, R; Simon, MJ	1
Billiards, SS; Folkerth, RD; Haynes, RL; Kinney, HC; Pierson, CR	1
Henshall, DC	1
Arthur, PG; Bogoyevitch, MA; Matich, GP; Pang, WW; Yu, DY	1
Brorson, JR; Li, D; Shao, Z; Vanden Hoek, TL	1
Bähr, M; Dietz, B; Dietz, GP	1
Chiulli, N; Codazzi, F; Di Cesare, A; Gravaghi, C; Grohovaz, F; Zacchetti, D	1
Düssmann, H; Huber, HJ; Nicholls, DG; Prehn, JH; Ward, MW; Weisová, P	1
Sapolsky, RM; Steinberg, GK; Zhao, H	1
Xu, X; Zheng, X	1
Fatokun, AA; Smith, RA; Stone, TW	1
Dethloff, TJ; Knudsen, GM; Larsen, FS	1
Caccia, S; Garattini, S; Ghezzi, P; Salmona, M; Takasaki, Y; Torii, K	1
Barke, KE; Hough, LB; Langlais, PJ; Weilersbacher, G; Zhang, SX	1
Ankarcrona, M; Bonfoco, E; Dypbukt, JM; Lipton, SA; Nicotera, P; Orrenius, S; Zhivotovsky, B	1
Fink, SL; Ho, DY; Lawrence, MS; Sapolsky, RM; Saydam, TC	1
Gaspary, HL; Graham, SH; Simon, RP	1
Dietrich, WD; Ginsberg, MD; Markgraf, CG; Prado, R; Watson, BD; Yao, H	1
Li, LX; Wang, ZC; Xu, CQ	1
Ferriero, DM; Kim, YS; Leib, SL; Täuber, MG	1
Dunn, D; Farnworth, M; Gyte, A; Lock, EA; Moore, RB; Simpson, MG; Widdowson, PS; Wyatt, I	1
Armato, U; Carcereri de Prati, A; Mariotto, S; Menegazzi, M; Suzuki, H	1
Ankarcrona, M; Dypbukt, JM; Nicotera, P; Orrenius, S	1
Aja, TJ; Alnemri, ES; Armstrong, RC; Bai, X; Fritz, LC; Gaur, S; Hoang, KD; Karanewsky, DS; Litwack, G; Tomaselli, KJ	1
Ankarcrona, M; Bonfoco, E; Lipton, SA; Nicotera, P; Orrenius, S	1
Coutts, CT; Foster, J; Gyte, A; Upton, R; Widdowson, PS; Wyatt, I	1
Huerbin, M; Kawaguchi, K; Simon, RP	1
De Weille, JR; Lauritzen, I; Lazdunski, M	1
Alcantara, F; Kirchgessner, AL; Liu, MT	1
Aggarwal, N; Baethmann, A; Eriskat, J; Plesnila, M; Stoffel, M	1
Gwag, BJ; Kim, EY; Sohn, S	1
Basile, AS; Fossom, L; Goping, G; Sei, Y; Skolnick, P	1
Fuse, T; Klein, ML; Nguyen, S; Shah, PT; Yoon, KW	1
Leist, M; Nicotera, P	1
Bossenmeyer, C; Chihab, R; Daval, JL; Oillet, J	2
Maher, P; Tan, S; Wood, M	1
Barger, SW; Hutchins, JB	1
Fernstrom, JD; Goldsmith, PC; Hu, L	1
Ankarcrona, M	1
Comas, T; Fournier, M; Monette, R; Morley, P; Small, DL	1
Fern, R; Möller, T	1
Glazner, GW; Mattson, MP	1
Beart, PM; Bernard, O; Cheung, NS; John, CA; Pascoe, CJ	1
DeGregorio-Rocasolano, N; Gasull, T; Trullas, R; Zapata, A	1
Beesley, J; Hirose, G; Kanemoto, M; Pleasure, D; Saiki, S; Yamaya, Y; Yoshioka, A	1
Chan, SL; Glazner, GW; Lu, C; Mattson, MP	1
Choi, D	1
Babcock, DJ; Choi, DW; Lee, JM; Zipfel, GJ	1
Favalli, L; Frattini, P; Govoni, S; Masoero, E; Rozza, A; Scelsi, R	1
Sapolsky, RM	1
Almeida, A; Bolaños, JP	1
Bergk, A; Dirnagl, U; Freyer, D; Harms, C; Herwig, U; Hörtnagl, H; Kapinya, K; Katchanov, J; Lautenschlager, M; Megow, D; Weber, JR	1
Igarashi, H; Katayama, Y; Kwee, IL; Nakada, T; Terashi, A	1
Griffin, JL; Nicholson, JK; Shore, RF; Walker, L	1
Bal-Price, A; Brown, GC	1
Dammaschk, T; Kaup, M; Mokrys, K; Ott, KH; Stratmann, U	1
Jevtovic-Todorovic, V; Olney, JW; Powell, S; Wozniak, DF	1
Li, Q; Miyashita, H; Shuaib, A; Yang, T; Yang, Y	1
Ferrer, I; Puig, B	1
Kim, J; Kim, SR; Kim, SY; Kim, YC; Lee, MK; Markelonis, GJ; Oh, TH; Park, EJ; Park, MJ; Sung, SH	1
Baethmann, A; Eriskat, J; Fürst, M; Plesnila, N; Stoffel, M	1
Labruyere, J; Olney, JW; Price, MT; Samson, L	2
Beart, PM; Christie, MJ; James, LB	1

Reviews

13 review(s) available for glutamic acid and Necrosis

Article	Year
[Calcium ions, glutaminate acid, hypothalamic-pituitary-adrenal axis, calcium dependent ATP-ase as causes of oxidative damage in depression patients (part II)]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 24, Issue:139 Topics: Apoptosis; Calcium; Calcium-Transporting ATPases; Depressive Disorder; Glutamic Acid; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Mitochondria; Necrosis; Neurons; Oxidative Phosphorylation; Reactive Oxygen Species; Tricarboxylic Acids	2008
Clinical characteristics and pathophysiological mechanisms of focal and diffuse traumatic brain injury. Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:10 Topics: Brain Edema; Brain Injuries; Calpain; Caspases; Diffuse Axonal Injury; Excitatory Amino Acids; Glasgow Coma Scale; Glutamic Acid; Humans; Injury Severity Score; Magnetic Resonance Imaging; Mitochondria; Necrosis; Neurotransmitter Agents	2010
Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures. Current molecular medicine, 2004, Volume: 4, Issue:2 Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Cell Death; Cells, Cultured; Electron Transport; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Membrane Potentials; Mitochondria; Mitochondrial Proton-Translocating ATPases; Models, Biological; Necrosis; Neurons; Nitric Oxide; Oxidative Stress; Oxygen; Reactive Oxygen Species; Superoxides; Synapses	2004
Is the late preterm infant more vulnerable to gray matter injury than the term infant? Clinics in perinatology, 2006, Volume: 33, Issue:4 Topics: Apoptosis; Brain; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Necrosis; Neurons	2006
General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:12 Topics: Animals; Apoptosis; Brain; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Glutamic Acid; Humans; Hypothermia, Induced; Hypoxia; Necrosis; Signal Transduction; Stroke	2007
[Effect of excitatory amino acids, Ca2+ on delayed neuronal death in hippocampus following transient forebrain ischemia]. Sheng li ke xue jin zhan [Progress in physiology], 1993, Volume: 24, Issue:2 Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Calcium-Transporting ATPases; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Necrosis; Neurons	1993
Nitric oxide in the liver: physiopathological roles. Advances in neuroimmunology, 1995, Volume: 5, Issue:4 Topics: Animals; Apoptosis; Brain; DNA Damage; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Free Radicals; Genes, p53; Glutamic Acid; Macrophages; Mice; Necrosis; Neurons; Nitric Oxide; Nitric Oxide Synthase; Pancreas; Receptors, N-Methyl-D-Aspartate; Signal Transduction	1995
Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress. Advances in neurology, 1997, Volume: 72 Topics: Animals; Apoptosis; Glutamic Acid; Humans; Mitochondria; Necrosis; Neurons; Nitric Oxide; Oxidative Stress	1997
Calcium and neuronal death. Reviews of physiology, biochemistry and pharmacology, 1998, Volume: 132 Topics: Animals; Apoptosis; Calcium; Glutamic Acid; Homeostasis; Humans; Intracellular Membranes; Necrosis; Neurodegenerative Diseases; Neurons; Nitric Oxide Synthase; Phosphorylation; Signal Transduction	1998
Why neurons die: cell death in the nervous system. The Anatomical record, 1998, Volume: 253, Issue:3 Topics: Animals; Apoptosis; Calcium; Cell Death; Free Radicals; Glutamic Acid; Humans; Immunohistochemistry; Microscopy, Phase-Contrast; Necrosis; Neurons	1998
Glutamate induced cell death: apoptosis or necrosis? Progress in brain research, 1998, Volume: 116 Topics: Animals; Apoptosis; Cell Death; Glutamic Acid; Humans; Necrosis; Neurons; Neurotoxins	1998
Neuronal apoptosis after CNS injury: the roles of glutamate and calcium. Journal of neurotrauma, 2000, Volume: 17, Issue:10 Topics: Animals; Apoptosis; Brain Injuries; Brain Ischemia; Calcium; Calcium Signaling; Glutamic Acid; Humans; Necrosis; Nerve Degeneration; Neuroprotective Agents; Neurotoxins	2000
Cellular defenses against excitotoxic insults. Journal of neurochemistry, 2001, Volume: 76, Issue:6 Topics: Animals; Apoptosis; Brain; Calcium Signaling; Glutamic Acid; Models, Neurological; Necrosis; Neurons; Neurotoxins	2001

Other Studies

100 other study(ies) available for glutamic acid and Necrosis

Article	Year
Role of CAST-Drp1 Pathway in Retinal Neuron-Regulated Necrosis in Experimental Glaucoma. Current medical science, 2023, Volume: 43, Issue:1 Topics: Animals; Calpain; Dynamins; Glaucoma; Glutamic Acid; Necrosis; Rats; Retinal Neurons	2023
Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells. Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:17 Topics: AMP-Activated Protein Kinases; Autophagosomes; Autophagy; Autophagy-Related Protein-1 Homolog; Beclin-1; Cell Line, Tumor; Energy Metabolism; Forkhead Box Protein O3; Glutamic Acid; Humans; Ibotenic Acid; Intracellular Signaling Peptides and Proteins; Mechanistic Target of Rapamycin Complex 1; Memantine; Microtubule-Associated Proteins; Necrosis; Neuroblastoma; Nutrients; Receptors, N-Methyl-D-Aspartate; Sequestosome-1 Protein; Transcription, Genetic	2020
Live Animal Imaging and Cell Sorting Methods for Investigating Neurodegeneration in a C. elegans Excitotoxic Necrosis Model. Journal of visualized experiments : JoVE, 2021, 01-22, Issue:167 Topics: Aging; Animal Husbandry; Animals; Apoptosis; Buffers; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Flow Cytometry; Glutamic Acid; Imaging, Three-Dimensional; Mitochondria; Necrosis; Nerve Degeneration; Neurons; Neuroprotection; Neurotoxins; Risk Factors; RNA; Transcriptome	2021
The Evaluation of BMAA Inhalation as a Potential Exposure Route Using a rat Model. Neurotoxicity research, 2018, Volume: 33, Issue:1 Topics: Amino Acids, Diamino; Animals; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Inhalation Exposure; Male; Necrosis; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Tritium	2018
Autocrine, paracrine and necrotic NMDA receptor signalling in mouse pancreatic neuroendocrine tumour cells. Open biology, 2017, Volume: 7, Issue:12 Topics: Action Potentials; Animals; Autocrine Communication; Calcium Signaling; Cell Line; Glutamic Acid; Mice; Mice, Inbred C57BL; Necrosis; Neuroendocrine Tumors; Pancreatic Neoplasms; Paracrine Communication; Receptors, N-Methyl-D-Aspartate	2017
Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis. Journal of lipid research, 2018, Volume: 59, Issue:2 Topics: Animals; Cells, Cultured; Female; Glutamic Acid; Mice; Mitochondria; Necrosis; Oligodendroglia; Pregnancy; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase	2018
Cylindromatosis mediates neuronal cell death in vitro and in vivo. Cell death and differentiation, 2018, Volume: 25, Issue:8 Topics: Animals; Apoptosis; Benzoquinones; Brain Injuries, Traumatic; Cell Line; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Glutamic Acid; GTPase-Activating Proteins; Imidazoles; Indoles; Lactams, Macrocyclic; Mice; Mice, Knockout; Necrosis; Neurons; NF-kappa B; Receptor-Interacting Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Ubiquitination	2018
Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2019, Volume: 221 Topics: Animals; Calpain; Disease Models, Animal; Glutamic Acid; Necrosis; Rats; Rats, Sprague-Dawley; Retinal Neurons	2019
Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis. Journal of cell science, 2018, 11-19, Volume: 131, Issue:22 Topics: Axons; Glutamic Acid; Humans; Necrosis; Nerve Degeneration	2018
Non-canonical activation of CREB mediates neuroprotection in a Caenorhabditis elegans model of excitotoxic necrosis. Journal of neurochemistry, 2019, Volume: 148, Issue:4 Topics: Animals; Caenorhabditis elegans; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Glutamic Acid; Necrosis; Nerve Degeneration; Neuroprotection; Neurotoxins	2019
Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate. Cell death & disease, 2013, May-16, Volume: 4 Topics: Animals; Apoptosis; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Male; Necrosis; Neurons; Neuropeptide Y; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Retina	2013
Study of the protective effect of calcium channel blockers against neuronal damage induced by glutamate in cultured hippocampal neurons. Pharmacological reports : PR, 2013, Volume: 65, Issue:3 Topics: Animals; Apoptosis; Calcium Channel Blockers; Cell Death; Cells, Cultured; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Necrosis; Nervous System Diseases; Neurons; Rats; Rats, Sprague-Dawley	2013
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke. Free radical biology & medicine, 2013, Volume: 65 Topics: Adaptor Proteins, Vesicular Transport; Animals; Astrocytes; Cells, Cultured; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Male; Membrane Glycoproteins; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Necrosis; Nerve Tissue Proteins; Oxidative Stress; Reactive Oxygen Species	2013
Cytoprotection by endogenous zinc in the vertebrate retina. Journal of neurochemistry, 2014, Volume: 129, Issue:2 Topics: Animals; Cell Survival; Chelating Agents; Dark Adaptation; Data Interpretation, Statistical; Excitatory Amino Acid Agonists; Eye; Glutamic Acid; Histidine; Kainic Acid; Necrosis; Photoreceptor Cells, Vertebrate; Retina; Skates, Fish; Zinc	2014
Estradiol alleviates the ischemic brain injury-induced decrease of neuronal calcium sensor protein hippocalcin. Neuroscience letters, 2014, Oct-17, Volume: 582 Topics: Animals; Apoptosis; Brain Ischemia; Calcium; Cells, Cultured; Cerebral Cortex; Estradiol; Female; Glutamic Acid; Hippocalcin; Hippocampus; Infarction, Middle Cerebral Artery; Mice; Necrosis; Neurons; Proteome; Rats, Sprague-Dawley	2014
Neuroprotective effect of astaxanthin against rat retinal ganglion cell death under various stresses that induce apoptosis and necrosis. Molecular vision, 2014, Volume: 20 Topics: Animals; Antioxidants; Apoptosis; Cell Hypoxia; Cell Survival; Cells, Cultured; Glutamic Acid; Necrosis; Neuroprotective Agents; Oxidative Stress; Rats; Retinal Ganglion Cells; Xanthophylls	2014
Pyrroloquinoline quinone against glutamate-induced neurotoxicity in cultured neural stem and progenitor cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015, Volume: 42 Topics: Animals; Annexin A5; Anthracenes; Apoptosis; Bromodeoxyuridine; Caspase 3; Cell Nucleus Size; Cell Survival; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glutamic Acid; Glutathione; Glutathione Peroxidase; Hippocampus; Necrosis; Neurons; PQQ Cofactor; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sincalide; Stem Cells	2015
Pro-apoptotic Action of Corticosterone in Hippocampal Organotypic Cultures. Neurotoxicity research, 2016, Volume: 30, Issue:2 Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Cell Survival; Cells, Cultured; Corticosterone; Disease Models, Animal; Female; Glutamic Acid; Hippocampus; Male; Necrosis; Nerve Growth Factor; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Tumor Necrosis Factor-alpha	2016
Diagnosing necrotic meningioma: a distinctive imaging pattern in diffusion MRI and MR spectroscopy. The neuroradiology journal, 2017, Volume: 30, Issue:1 Topics: Choline; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Necrosis; Tritium	2017
Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil. Journal of neuroscience research, 2008, Volume: 86, Issue:16 Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Cytoprotection; Donepezil; Enzyme Inhibitors; Glutamic Acid; Indans; Ionomycin; Ionophores; MAP Kinase Signaling System; Necrosis; Nerve Degeneration; Neurons; Neuroprotective Agents; Nicotinic Antagonists; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Nicotinic; Signal Transduction	2008
[Apoptosis and its receptor selective pathways during neurotoxic action of glutamate]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2008, Volume: 94, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Active Transport, Cell Nucleus; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Tumor Suppressor Protein p53	2008
Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. Journal of neuroinflammation, 2008, Oct-09, Volume: 5 Topics: Animals; Cells, Cultured; Culture Media, Conditioned; Cytokines; Encephalitis; Gliosis; Glutamic Acid; Glutaminase; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Myeloid Differentiation Factor 88; Necrosis; Nerve Degeneration; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Toll-Like Receptors; Up-Regulation	2008
Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct. Brain research, 2009, Jan-12, Volume: 1248 Topics: Animals; Apoptosis; Brain Ischemia; Caspase 3; Cells, Cultured; Cerebral Cortex; Cerebral Infarction; Enzyme Activation; Glutamic Acid; Guanidines; In Situ Nick-End Labeling; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Necrosis; Neurons; Neuroprotective Agents; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Thiophenes	2009
Contribution of a mitochondrial pathway to excitotoxic neuronal necrosis. Journal of neuroscience research, 2009, Volume: 87, Issue:9 Topics: Animals; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cytochromes c; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Microscopy, Electron, Transmission; Mitochondria; Necrosis; Neurons; Neurotoxins; Rats; Rats, Wistar; Signal Transduction	2009
Apoptosis and the receptor specificity of its mechanisms during the neurotoxic action of glutamate. Neuroscience and behavioral physiology, 2009, Volume: 39, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Active Transport, Cell Nucleus; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Tumor Suppressor Protein p53	2009
Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells. European journal of pharmacology, 2009, Sep-01, Volume: 617, Issue:1-3 Topics: Animals; Apoptosis; Cell Line; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitochondria; Necrosis; Neurotoxins; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Time Factors	2009
Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal culture. Journal of anesthesia, 2009, Volume: 23, Issue:3 Topics: Animals; Antipyrine; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Edaravone; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Free Radical Scavengers; Glutamic Acid; Necrosis; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reactive Oxygen Species	2009
Dual effect of glutamate on GABAergic interneuron survival during cerebral cortex development in mice neonates. Cerebral cortex (New York, N.Y. : 1991), 2010, Volume: 20, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Calcium; Caspase 3; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; N-Methylaspartate; Necrosis; RNA, Small Interfering	2010
Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest. The Annals of thoracic surgery, 2010, Volume: 89, Issue:2 Topics: Animals; Apoptosis; Brain; Circulatory Arrest, Deep Hypothermia Induced; Citrulline; Dizocilpine Maleate; DNA Fragmentation; Dogs; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Glycine; In Situ Nick-End Labeling; Microdialysis; Microscopy, Electron; Necrosis; Neurons; Nitric Oxide; Reperfusion Injury	2010
The role of PARP activation in glutamate-induced necroptosis in HT-22 cells. Brain research, 2010, Jul-09, Volume: 1343 Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Cell Line, Transformed; Enzyme Inhibitors; Glutamic Acid; Imidazoles; Indoles; Methylnitronitrosoguanidine; Mice; Necrosis; Nerve Degeneration; Neurotoxins; Oxidative Stress; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases	2010
Effect of mild and moderate hypothermia on hypoxic injury in nearly pure neuronal culture. Journal of anesthesia, 2010, Volume: 24, Issue:5 Topics: Animals; Apoptosis; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Electrochemistry; Female; Glutamic Acid; Hypothermia, Induced; Mitochondria; Necrosis; Neurons; Pregnancy; Rats; Rats, Wistar	2010
Chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation. Neurochemical research, 2011, Volume: 36, Issue:5 Topics: Animals; Cell Death; Chronic Disease; Glucose; Glutamic Acid; Hippocampus; Hypoxia; L-Lactate Dehydrogenase; Lithium Compounds; Male; Necrosis; Rats; Rats, Wistar; Stress, Physiological	2011
tPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury. Journal of neurotrauma, 2012, Jun-10, Volume: 29, Issue:9 Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cerebral Arteries; Cerebrovascular Circulation; Enzyme-Linked Immunosorbent Assay; Female; Glutamic Acid; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Necrosis; Polymerase Chain Reaction; Prostaglandins; Receptors, N-Methyl-D-Aspartate; Swine; Tissue Plasminogen Activator	2012
Minocycline cannot protect neurons against bilirubin-induced hyperexcitation in the ventral cochlear nucleus. Experimental neurology, 2012, Volume: 237, Issue:1 Topics: Animals; Apoptosis; Bilirubin; Excitatory Amino Acids; Glutamic Acid; Minocycline; Necrosis; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Ventral Thalamic Nuclei	2012
Effects of AMPA-receptor and voltage-sensitive sodium channel blockade on high potassium-induced glutamate release and neuronal death in vivo. Brain research, 2002, Aug-09, Volume: 946, Issue:1 Topics: Amygdala; Animals; Cell Death; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Male; Necrosis; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin	2002
Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals. The Journal of physiology, 2002, Sep-01, Volume: 543, Issue:Pt 2 Topics: Acid Sensing Ion Channels; Acidosis; Animals; Arachidonic Acid; Brain Ischemia; Cations; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen-Ion Concentration; Lactic Acid; Membrane Potentials; Membrane Proteins; Necrosis; Nerve Tissue Proteins; Purkinje Cells; Rats; Signal Transduction; Sodium; Sodium Channels	2002
Ultrastructural clues for glutamate-induced necrosis in parietal and cerebellar neurons. Fundamental & clinical pharmacology, 2003, Volume: 17, Issue:3 Topics: Animals; Cerebellar Cortex; Glutamic Acid; In Vitro Techniques; Male; Necrosis; Neurons; Parietal Lobe; Rats; Rats, Sprague-Dawley	2003
Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology. Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calpain; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Drug Synergism; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Immunoblotting; Immunohistochemistry; Necrosis; Neurons; Neurotoxins; Nitro Compounds; Oligopeptides; Propionates; Rats; Spectrin; Time Factors	2003
[Behavior of serum transaminase activity (glutamic acid-ox-alacetic acid transaminase) in allyl alcohol necrosis of rat liver]. Klinische Wochenschrift, 1957, Apr-01, Volume: 35, Issue:7 Topics: Alcohols; Animals; Glutamic Acid; Liver; Necrosis; Propanols; Rats; Transaminases	1957
Differential neuronal fates in the CA1 hippocampus after hypoxia in newborn and 7-day-old rats: effects of pre-treatment with MK-801. Hippocampus, 2003, Volume: 13, Issue:8 Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Cell Death; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hypoxia, Brain; Necrosis; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2003
In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death. Hippocampus, 2004, Volume: 14, Issue:5 Topics: Animals; Apoptosis; Brain; Brain Injuries; Cell Death; Cell Survival; Denervation; Disease Models, Animal; Energy Metabolism; Fornix, Brain; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hippocampus; L-Lactate Dehydrogenase; Lactic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley	2004
Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone. Neuroscience, 2005, Volume: 131, Issue:1 Topics: Animals; Animals, Newborn; Calcium; Cell Division; Cell Survival; Cerebral Ventricles; Fibroblast Growth Factor 2; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; L-Lactate Dehydrogenase; Necrosis; Nerve Growth Factor; Nerve Growth Factors; Neurons; Oligodendroglia; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells	2005
Roscovitine triggers excitotoxicity in cultured granule neurons by enhancing glutamate release. Molecular pharmacology, 2005, Volume: 68, Issue:5 Topics: Action Potentials; Animals; Calcium; Calcium Channels, L-Type; Calcium Channels, N-Type; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Glutamic Acid; Necrosis; Neurons; Potassium Channel Blockers; Potassium Chloride; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Roscovitine; Synaptic Transmission	2005
The electrical response of cerebellar Purkinje neurons to simulated ischaemia. Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 10 Topics: Action Potentials; Amino Acid Transport System X-AG; Animals; Calcium; Cerebellum; Excitatory Amino Acid Transporter 2; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia; Ischemia; Mice; Mice, Transgenic; Necrosis; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA	2005
Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells. Neurobiology of disease, 2005, Volume: 20, Issue:2 Topics: Age Factors; Animals; Animals, Newborn; Astrocytes; Bilirubin; Causality; Cell Death; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Cytokines; Encephalitis; Glutamic Acid; Humans; Infant, Newborn; Inflammation Mediators; Kernicterus; Lipopolysaccharides; Necrosis; Premature Birth; Rats; Rats, Wistar	2005
Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition. Neurobiology of disease, 2006, Volume: 22, Issue:1 Topics: Animals; Animals, Newborn; Apoptosis; Biomarkers; Brain Injuries; Calpain; Caspase 3; Caspases; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mechanotransduction, Cellular; Necrosis; Neurons; Organ Culture Techniques; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spectrin; Synaptic Transmission; Up-Regulation	2006
Apoptosis signalling pathways in seizure-induced neuronal death and epilepsy. Biochemical Society transactions, 2007, Volume: 35, Issue:Pt 2 Topics: Apoptosis; Brain; Caspases; Cell Death; Endoplasmic Reticulum; Epilepsy; Glutamic Acid; Humans; Necrosis; Neurons; Proto-Oncogene Proteins c-bcl-2; Seizures; Signal Transduction	2007
Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase. Journal of neurochemistry, 2007, Volume: 102, Issue:1 Topics: Animals; Apoptosis; Blotting, Western; Calcium; Caspase 3; Cytosol; Enzyme Inhibitors; Excitatory Amino Acids; Fluorescent Dyes; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondrial Membranes; Necrosis; Neurons; Oxygen Consumption; Peptides; Phosphorylation; Rats; Reactive Oxygen Species; Superoxides	2007
Reperfusion accelerates acute neuronal death induced by simulated ischemia. Experimental neurology, 2007, Volume: 206, Issue:2 Topics: Acidosis, Respiratory; Animals; Apoptosis; Cell Death; Cell Membrane; Cells, Cultured; Cytoskeleton; Glucose; Glutamic Acid; Hypercapnia; Hypoxia-Ischemia, Brain; Mice; Mice, Inbred C57BL; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Potassium; Reperfusion Injury; Time Factors	2007
Bcl-xL protects cerebellar granule neurons against the late phase, but not against the early phase of glutamate-induced cell death. Brain research, 2007, Aug-20, Volume: 1164 Topics: Animals; Animals, Newborn; Apoptosis; bcl-X Protein; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cerebellar Cortex; Cytoprotection; Glutamic Acid; Necrosis; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley	2007
Sphingosylphosphocholine effects on cultured astrocytes reveal mechanisms potentially involved in neurotoxicity in Niemann-Pick type A disease. The European journal of neuroscience, 2007, Volume: 26, Issue:4 Topics: Animals; Apoptosis; Astrocytes; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Fluorescent Dyes; Fura-2; Glutamic Acid; Hippocampus; Microscopy, Video; Necrosis; Nerve Degeneration; Neurotoxicity Syndromes; Niemann-Pick Disease, Type A; Phenotype; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Sphingosine	2007
Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Aug-01, Volume: 27, Issue:31 Topics: Animals; Apoptosis; Cell Membrane; Cells, Cultured; Cerebellum; Drug Tolerance; Female; Glutamic Acid; Male; Membrane Potentials; Mitochondrial Membranes; Necrosis; Neurons; Rats; Rats, Wistar	2007
Potential involvement of calcium and nitric oxide in protective effects of puerarin on oxygen-glucose deprivation in cultured hippocampal neurons. Journal of ethnopharmacology, 2007, Sep-25, Volume: 113, Issue:3 Topics: Animals; Apoptosis; Calcium; Cell Hypoxia; Cells, Cultured; Glucose; Glutamic Acid; Hippocampus; Isoflavones; Necrosis; Neurons; Nitric Oxide; Protective Agents; Rats; Rats, Sprague-Dawley	2007
Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons. Experimental brain research, 2008, Volume: 186, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cytarabine; Glutamic Acid; Kynurenic Acid; Necrosis; Neurons; Rats; Rats, Sprague-Dawley; Xanthines	2008
Cerebral blood flow autoregulation in experimental liver failure. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:5 Topics: Ammonia; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Glutamic Acid; Glutamine; Homeostasis; Intracranial Hypertension; Intracranial Pressure; Laser-Doppler Flowmetry; Liver Failure, Acute; Male; Models, Cardiovascular; Necrosis; Rats; Rats, Wistar; Water	2008
Pyroglutamate kinetics and neurotoxicity studies in mice. Toxicology letters, 1983, Volume: 16, Issue:3-4 Topics: Animals; Arcuate Nucleus of Hypothalamus; Brain; Brain Diseases; Female; Glutamates; Glutamic Acid; Kinetics; Male; Mice; Mice, Inbred ICR; Necrosis; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Sodium Glutamate	1983
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy. Journal of neuroscience research, 1994, Aug-01, Volume: 38, Issue:5 Topics: Animals; Cell Death; Disease Models, Animal; Gliosis; Glutamic Acid; Glutamine; Hippocampus; Histamine; Histamine Release; Male; Methylhistidines; Microdialysis; Necrosis; Nerve Degeneration; Neuroglia; Pyrithiamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy	1994
Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron, 1995, Volume: 15, Issue:4 Topics: Animals; Apoptosis; Cerebellum; Chromatin; DNA; Glutamic Acid; Membrane Potentials; Mitochondria; Molecular Weight; Necrosis; Neurons; Rats; Rats, Sprague-Dawley	1995
Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults. Journal of neurochemistry, 1995, Volume: 65, Issue:2 Topics: Animals; Brain; Chlorocebus aethiops; Defective Viruses; Gene Expression; Genetic Vectors; Glutamic Acid; Hypoglycemia; Monosaccharide Transport Proteins; Necrosis; Neurons; Neurotoxins; Nitro Compounds; Promoter Regions, Genetic; Propionates; Rats; Rats, Sprague-Dawley; Simplexvirus; Vero Cells	1995
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury	1994
Glutamate antagonist MK-801 attenuates incomplete but not complete infarction in thrombotic distal middle cerebral artery occlusion in Wistar rats. Brain research, 1994, Apr-11, Volume: 642, Issue:1-2 Topics: Animals; Cerebral Infarction; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Intracranial Embolism and Thrombosis; Male; Necrosis; Neurons; Neurotransmitter Agents; Rats; Rats, Wistar	1994
Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis. The Journal of infectious diseases, 1996, Volume: 173, Issue:1 Topics: Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Cerebral Cortex; Cerebrospinal Fluid; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Meningitis, Bacterial; Necrosis; Neurons; Rats; Rats, Sprague-Dawley; Streptococcal Infections; Streptococcus agalactiae	1996
Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis. British journal of pharmacology, 1996, Volume: 117, Issue:8 Topics: Animals; Aspartic Acid; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrocarbons, Chlorinated; In Vitro Techniques; Indazoles; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Propionates; Rats	1996
Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEBS letters, 1996, Oct-07, Volume: 394, Issue:3 Topics: Animals; Apoptosis; Calcineurin; Calmodulin-Binding Proteins; Cells, Cultured; Cerebellum; Cyclosporine; Glutamic Acid; Membrane Potentials; Mitochondria; Necrosis; Neurons; Phosphoprotein Phosphatases; Rats; Tacrolimus	1996
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebellar Cortex; Coumarins; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Enzyme Precursors; Glutamic Acid; Ketones; Mice; Mice, Inbred C57BL; Necrosis; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Potassium; Protein Synthesis Inhibitors	1997
Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis. Toxicology and applied pharmacology, 1997, Volume: 142, Issue:2 Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Aspartic Acid; Blotting, Western; Calpain; Cerebellum; Free Radicals; Glutamic Acid; Hydrocarbons, Chlorinated; Lipid Peroxidation; Male; Necrosis; Nervous System Diseases; Neurons; Oxidative Stress; Propionates; Rats; Spectrin	1997
Lesioning of deep prepiriform cortex protects against ischemic neuronal necrosis by attenuating extracellular glutamate concentrations. Journal of neurochemistry, 1997, Volume: 69, Issue:1 Topics: Animals; Brain Ischemia; Cell Death; Cerebral Cortex; Cyclooxygenase 2; Extracellular Space; Gene Expression Regulation, Enzymologic; Glutamic Acid; Hippocampus; In Situ Hybridization; Isoenzymes; Male; Microdialysis; Necrosis; Neurons; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures	1997
The potassium channel opener (-)-cromakalim prevents glutamate-induced cell death in hippocampal neurons. Journal of neurochemistry, 1997, Volume: 69, Issue:4 Topics: Animals; Apoptosis; Calcium; Cell Death; Cells, Cultured; Cromakalim; Glutamic Acid; Glyburide; Hippocampus; Necrosis; Neurons; Osmolar Concentration; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Stereoisomerism	1997
Excitotoxicity in the enteric nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-15, Volume: 17, Issue:22 Topics: Animals; Antibody Specificity; Apoptosis; Cells, Cultured; Enteric Nervous System; Excitatory Amino Acid Agonists; Ganglia; Glutamic Acid; Guinea Pigs; Kainic Acid; Male; Membrane Potentials; Mitochondria; N-Methylaspartate; Necrosis; Neurites; Neurons; Neurotoxins; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate	1997
The penumbra zone of a traumatic cortical lesion: a microdialysis study of excitatory amino acid release. Acta neurochirurgica. Supplement, 1997, Volume: 70 Topics: Animals; Aspartic Acid; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Male; Microdialysis; Necrosis; Rats; Rats, Sprague-Dawley	1997
Glutamate neurotoxicity in mouse cortical neurons: atypical necrosis with DNA ladders and chromatin condensation. Neuroscience letters, 1998, Jan-16, Volume: 240, Issue:3 Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Chromatin; DNA Fragmentation; Fetus; Glutamic Acid; Mice; Microscopy, Electron; Necrosis	1998
Quinolinic acid protects rat cerebellar granule cells from glutamate-induced apoptosis. Neuroscience letters, 1998, Jan-30, Volume: 241, Issue:2-3 Topics: Animals; Apoptosis; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Logistic Models; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Quinolinic Acid; Rats; Rats, Sprague-Dawley	1998
Indirect glutamate neurotoxicity. Journal of neurotrauma, 1998, Volume: 15, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Apoptosis; Cell Death; Culture Techniques; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Necrosis; Neuroglia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley	1998
Glutamate triggers cell death specifically in mature central neurons through a necrotic process. Molecular genetics and metabolism, 1998, Volume: 63, Issue:2 Topics: Animals; Cell Death; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glutamic Acid; N-Methylaspartate; Necrosis; Nerve Tissue Proteins; Neurons; Prosencephalon; Rats; Rats, Sprague-Dawley; Time Factors	1998
Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. Journal of neurochemistry, 1998, Volume: 71, Issue:1 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Aurintricarboxylic Acid; Buthionine Sulfoximine; Cell Line, Transformed; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Glutamic Acid; Glutathione Synthase; Hippocampus; Mice; Microscopy, Electron; Necrosis; Neurons; Oxidative Stress; Protein Kinase C; Protein Synthesis Inhibitors; RNA; Sulfones; Trypsin Inhibitors	1998
Exogenous glutamate enhances glutamate receptor subunit expression during selective neuronal injury in the ventral arcuate nucleus of postnatal mice. Neuroendocrinology, 1998, Volume: 68, Issue:2 Topics: Animals; Animals, Suckling; Apoptosis; Arcuate Nucleus of Hypothalamus; Brain Chemistry; Cerebral Ventricles; Dose-Response Relationship, Drug; Female; Food Additives; Glutamic Acid; Immunohistochemistry; Median Eminence; Mice; Mice, Inbred Strains; Microscopy, Electron; Necrosis; Nerve Degeneration; Neurons; Receptors, Glutamate; Sodium Glutamate; Tyrosine 3-Monooxygenase	1998
Lack of correlation between the effects of transient exposure to glutamate and those of hypoxia/reoxygenation in immature neurons in vitro. Journal of neurochemistry, 1998, Volume: 71, Issue:3 Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cellular Senescence; Energy Metabolism; Glutamic Acid; Hypoxia; Necrosis; Neurons; Oxygen; Rats; Time Factors	1998
Loss of cyclin D1 in necrotic and apoptotic models of cortical neuronal degeneration. Brain research, 1999, Sep-25, Volume: 842, Issue:2 Topics: Animals; Apoptosis; Cell Cycle; Cells, Cultured; Cerebral Cortex; Cyclin D1; Fetus; G1 Phase; Glutamic Acid; Kinetics; Models, Neurological; Necrosis; Nerve Degeneration; Neurons; Rats; Resting Phase, Cell Cycle; S Phase; Staurosporine	1999
Rapid ischemic cell death in immature oligodendrocytes: a fatal glutamate release feedback loop. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jan-01, Volume: 20, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Brain Ischemia; Calcium; Cell Death; Cell Size; Cells, Cultured; Cellular Senescence; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Feedback; Glutamic Acid; Necrosis; Oligodendroglia; Rats; Rats, Long-Evans; Receptors, Glutamate	2000
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity. Experimental neurology, 2000, Volume: 161, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Calcium; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Embryo, Mammalian; Glutamic Acid; Homeostasis; Kinetics; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha	2000
Human Bcl-2 protects against AMPA receptor-mediated apoptosis. Journal of neurochemistry, 2000, Volume: 74, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; DNA; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Genotype; Glutamic Acid; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Microscopy, Fluorescence; Necrosis; Neocortex; Neurons; Neurotoxins; Oxidants; Proto-Oncogene Proteins c-bcl-2; Receptors, AMPA; Staurosporine	2000
Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation. The Journal of biological chemistry, 2000, Jun-16, Volume: 275, Issue:24 Topics: Animals; Blood; Cell Death; Cells, Cultured; Cerebellum; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Glutamic Acid; Hydrolysis; Membrane Lipids; N-Methylaspartate; Necrosis; Neurons; Phosphatidylcholines; Phospholipids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2000
Non-N-methyl-D-aspartate glutamate receptors mediate oxygen--glucose deprivation-induced oligodendroglial injury. Brain research, 2000, Jan-31, Volume: 854, Issue:1-2 Topics: Animals; Calcium; Cell Line; Culture Media; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia; Necrosis; Oligodendroglia; Osmolar Concentration; Rats; Receptors, Glutamate	2000
Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, May-15, Volume: 20, Issue:10 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calcium; Caspases; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; N-Methylaspartate; Necrosis; Neocortex; Nerve Degeneration; Nerve Growth Factors; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptosomes	2000
Stroke. Neurobiology of disease, 2000, Volume: 7, Issue:5 Topics: Animals; Apoptosis; Cycloheximide; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Intracranial Embolism; Necrosis; Neuroprotective Agents; Plasminogen Activators; Spinal Cord Injuries; Stroke; Tissue Plasminogen Activator	2000
Effect of acute alcohol on ischemia-induced glutamate release and brain damage. Alcohol (Fayetteville, N.Y.), 2000, Volume: 22, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Ethanol; Frontal Lobe; Glutamic Acid; Kinetics; Male; Necrosis; Rats; Rats, Wistar; Rose Bengal	2000
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons. Journal of neurochemistry, 2001, Volume: 77, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Cyclosporine; Electron Transport; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Membrane Potentials; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligomycins; omega-N-Methylarginine; Permeability; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Single-Blind Method; Succinate Cytochrome c Oxidoreductase	2001
Differential mechanisms of neuroprotection by 17 beta-estradiol in apoptotic versus necrotic neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-15, Volume: 21, Issue:8 Topics: Animals; Apoptosis; Aziridines; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Choline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Glucose; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Necrosis; Neurons; Neuroprotective Agents; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Receptors, Estrogen; Septum of Brain; Staurosporine; Time Factors	2001
1H magnetic resonance spectroscopic imaging of permanent focal cerebral ischemia in rat: longitudinal metabolic changes in ischemic core and rim. Brain research, 2001, Jul-13, Volume: 907, Issue:1-2 Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Caudate Nucleus; Circle of Willis; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Ligation; Magnetic Resonance Imaging; Male; Necrosis; Putamen; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Time Factors	2001
High-resolution magic angle spinning 1H-NMR spectroscopy studies on the renal biochemistry in the bank vole (Clethrionomys glareolus) and the effects of arsenic (As3+) toxicity. Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:6 Topics: Alanine; Animals; Arsenic; Arvicolinae; Creatine; Glutamic Acid; Glutamine; Kidney; Kidney Diseases; Magnetic Resonance Spectroscopy; Male; Muridae; Necrosis; Phosphorylcholine; Species Specificity	2001
Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Sep-01, Volume: 21, Issue:17 Topics: Adenosine Triphosphate; Animals; Cell Death; Cell Respiration; Cell Survival; Cells, Cultured; Cerebellum; Coculture Techniques; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Inflammation; Interferon-gamma; Lactic Acid; Lipopolysaccharides; Necrosis; Neuroglia; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Oxygen; Rats; Rats, Wistar	2001
Histocytological evaluation of the reaction of rat pulp tissue to Carisolv. Journal of dentistry, 2001, Volume: 29, Issue:4 Topics: Animals; Collagen; Dental Cavity Preparation; Dental Pulp; Erythrocytes; Glutamic Acid; Leucine; Lysine; Male; Microscopy, Electron, Scanning; Necrosis; Odontoblasts; Rats; Rats, Wistar	2001
Propofol and sodium thiopental protect against MK-801-induced neuronal necrosis in the posterior cingulate/retrosplenial cortex. Brain research, 2001, Sep-21, Volume: 913, Issue:2 Topics: Anesthetics, Intravenous; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Necrosis; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thiopental	2001
Different dynamic patterns of extracellular glutamate release in rat hippocampus after permanent or 30-min transient cerebral ischemia and histological correlation. Neuropathology : official journal of the Japanese Society of Neuropathology, 2001, Volume: 21, Issue:3 Topics: Animals; Astrocytes; Brain; Brain Ischemia; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Necrosis; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Reperfusion Injury; Up-Regulation	2001
Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat. Neuroscience letters, 2002, Mar-22, Volume: 321, Issue:3 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cytochrome c Group; Entorhinal Cortex; Fas Ligand Protein; Female; Glutamic Acid; Kainic Acid; Membrane Glycoproteins; Mitochondria; Necrosis; Neurons; Neurotoxins; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction	2002
Flavonoids of Inula britannica protect cultured cortical cells from necrotic cell death induced by glutamate. Free radical biology & medicine, 2002, Apr-01, Volume: 32, Issue:7 Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Cerebral Cortex; Flavonoids; Glutamic Acid; Glutathione; Inula; Necrosis; Neuroglia; Neurons; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2002
Release of excitatory amino acids in the penumbra of a focal cortical necrosis. Journal of neurotrauma, 2002, Volume: 19, Issue:4 Topics: Alanine; Animals; Aspartic Acid; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Glycine; Male; Microdialysis; Necrosis; Rats; Serine	2002
Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina. Brain research bulletin, 1985, Volume: 14, Issue:4 Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; Calcium; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Necrosis; Nicotinic Acids; Nimodipine; Pyrrolidines; Retina	1985
An excitatory amino acid projection from rat prefrontal cortex to periaqueductal gray. Brain research bulletin, 1986, Volume: 16, Issue:1 Topics: Animals; Aspartic Acid; Frontal Lobe; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Necrosis; Neurotransmitter Agents; Periaqueductal Gray; Rats; Rats, Inbred Strains; Synaptosomes	1986
The role of specific ions in glutamate neurotoxicity. Neuroscience letters, 1986, Mar-28, Volume: 65, Issue:1 Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Drug Synergism; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Necrosis; Retinal Degeneration; Sodium	1986