glutamic acid and Multiple Sclerosis

glutamic acid has been researched along with Multiple Sclerosis in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.95)	18.7374
1990's	4 (3.81)	18.2507
2000's	37 (35.24)	29.6817
2010's	48 (45.71)	24.3611
2020's	15 (14.29)	2.80

Authors

Authors	Studies
Castañares, C; Cristiano, E; Lopez, PH; Pappolla, A; Patrucco, L; Rojas, JI; Sánchez, F; Varela, L	1
An, J; Chai, Z; Chen, YY; Ding, ZB; Han, QX; He, Y; Ma, CG; Song, LJ; Wang, Q; Xiao, BG; Yin, JJ; Yu, JZ	1
Aharoni, R; Arnon, R; Chapman, J; Dori, A; Eilam, R; Lerner, S; Shavit-Stein, E	1
Lee, HG; Quintana, FJ; Wheeler, MA	1
Basso, PJ; Breda, CNS; Caldini, EG; Câmara, NOS; Cipelli, M; de Lima, J; Ghirotto, B; Hiyane, MI; Kowaltowski, AJ; Nakaya, HI; Oliveira, AER; Oliveira, DF; Oliveira, EML; Ribeiro, HC; Sertié, AL; Silva, CCC; Sussulini, A; Zatz, M	1
Emami Aleagha, MS; Mohammadi, P; Pashaei, S; Yarani, R	1
Akyuz, E; Angelopoulou, E; Aslan, FS; Celik, BR; Sahin, H	1
Dahlmanns, JK; Dahlmanns, M; Savaskan, N; Steiner, HH; Yakubov, E	1
Bassi, MS; Bellingacci, L; Bruno, A; Buttari, F; Centonze, D; Di Filippo, M; Di Maio, A; Dolcetti, E; Errico, F; Finardi, A; Furlan, R; Galifi, G; Gilio, L; Mancini, A; Nuzzo, T; Usiello, A	1
Pukoli, D; Vécsei, L	1
Bar-Or, A; Bueno, M; Charabati, M; de Faria Junior, O; Drake, SS; Dumas, A; Fournier, AE; Galloway, DA; Juźwik, CA; Lécuyer, MA; Moore, C; Morquette, B; Paradis-Isler, N; Prat, A; Rambaldi, I; Vallières, L; Zandee, S; Zhang, Y	1
Bittšanský, M; Čierny, D; Dobrota, D; Grendár, M; Hnilicová, P; Kantorová, E; Kurča, E; Lehotský, J; Poláček, H; Sivák, Š; Zeleňák, K	1
Bakhtiyarova, KZ; Kuzmina, US; Vakhitov, VA; Vakhitova, YV; Zainullina, LF	1
Birkner, K; Bitar, L; Bittner, S; Krämer-Albers, EM; Luchtman, D; Meuth, SG; Pape, K; Ruck, T; Schmaul, S; Stroh, A; Thalman, C; Wasser, B; Zipp, F	1
Abdel Naseer, M; Fouad, AM; Hassan, A; Rabah, AM; Rashed, LA	1
Gupta, R; Khera, R; Kumar, N; Mehan, S; Sharma, N	1
Al-Iedani, O; Arm, J; Lea, R; Lechner-Scott, J; Oeltzschner, G; Ramadan, S	1
Barkhof, F; Eijlers, AJ; Geurts, JJ; Klauser, AM; Pouwels, PJ; Schoonheim, MM; Uitdehaag, BM; Wiebenga, OT	1
Al Gawwam, G; Sharquie, IK	1
Bal, M; Darios, FD; Davletov, B; Flašker, A; García-Martinez, V; Gutiérrez, LM; Jorgacevski, J; Kavalali, ET; Leese, C; Nosyreva, E; Villanueva, J; Zorec, R	1
Bertolino, N; Dwyer, MG; Hagemeier, J; Krawiecki, JC; Modica, CM; Pol, S; Polak, P; Preda, M; Schweser, F; Siebert, DM; Sudyn, ML; Sveinsson, M; Zivadinov, R	1
Grendar, M; Hnilicova, P; Kantorova, E; Kurca, E; Polacek, H; Zelenak, K	1
Acharjee, S; Benediktsson, A; Benoit, L; Bisht, K; Gomez, CD; Lee, B; Pittman, QJ; Sharkey, KA; Tremblay, ME; Verbeek, M	1
Bagnato, F; Box, BA; Conrad, BN; Dula, AN; Landman, BA; Lyttle, BD; McKeithan, LJ; Newhouse, P; O'Grady, KP; Pawate, S; Smith, SA; Thompson, LM	1
Pedraz, B; Sammer, G	1
Alavi, MS; Barzegar, H; Fanoudi, S; Fard, AV; Hosseini, M; Sadeghnia, HR; Soukhtanloo, M	1
Gonzalez-Costa, M; Padron-Gonzalez, AA	1
Bullitta, S; Buttari, F; Centonze, D; Chiurchiù, V; De Vito, F; Fresegna, D; Gentile, A; Guadalupi, L; Leuti, A; Mandolesi, G; Marfia, GA; Musella, A; Rizzo, FR; Stampanoni Bassi, M; Vanni, V	1
Aalto, A; Landtblom, AM; Leinhard, OD; Lundberg, P; Smedby, Ö; Tisell, A; Warntjes, JB	1
Atlasi, MA; Azami Tameh, A; Beyer, C; Clarner, T; Hassanzadeh, G; Naderian, H	1
de Wit, SJ; Hamann, J; Huitinga, I; Melief, J; Swaab, D; Teunissen, C; Uitdehaag, BM; van Eden, CG	1
Arunachalam, P; Bernreuther, C; Daehn, T; Friese, MA; Gelderblom, M; Gerloff, C; Glatzel, M; Ludewig, P; Magnus, T; Matschke, J; Schattling, B	1
Bardelli, D; Bianchi, MG; Bussolati, O; Chiu, M	1
Bressler, J; Kaufmann, W; O'Driscoll, CM; Rojas, CJ; Slusher, BS; Thomas, AG	1
Colic, M; Cvetanovic, A; Dzopalic, T; Kostic, M; Marjanovic, G; Savic, V; Stojanovic, I; Vojinovic, S; Zivanovic, S; Zivkovic, N	1
Kostic, M; Ljubisavljevic, S; Stojanovic, IR	1
Azevedo, CJ; Chu, P; Cree, BA; Hauser, SL; Kornak, J; Nelson, SJ; Okuda, DT; Pelletier, D; Sampat, M	1
Centonze, D; Gentile, A; Mandolesi, G; Musella, A	1
D'Alessandro, M; Del Boccio, P; Di Ilio, C; di Ioia, M; Lugaresi, A; Pieragostino, D; Rossi, C; Sacchetta, P; Urbani, A; Zucchelli, M	1
Cawley, N; Ciccarelli, O; Edden, RA; Miller, DH; Muhlert, N; Solanky, BS; Thompson, AJ; Tur, C; Wheeler-Kingshott, CA	1
Evans, KA; Franklin, RJ; Gautier, HO; James, F; James, R; Káradóttir, RT; Lao-Peregrin, C; Lundgaard, I; Reynolds, R; Sitnikov, S; Volbracht, K	1
Birkenstock, J; Ellwardt, E; Gollan, R; Luchtman, D; Robohm, K; Siffrin, V; Zipp, F	1
LeVine, SM	1
de Graaf, RA; Juchem, C; Mason, GF; Pelletier, D; Prinsen, H	1
Docagne, F; Lipton, SA; Macrez, R; Stys, PK; Vivien, D	1
Colic, M; Cvetanovic, A; Kostic, M; Stojanovic, I; Zivkovic, N	1
Brown, RA; Hoge, RD; Holmes, SA; Koski, L; Nantes, JC; Narayanan, S; Proulx, S; Zhong, J	1
Bende, Z; Majláth, Z; Pukoli, D; Rajda, C; Vécsei, L	1
Levite, M	1
Chalifoux, S; Giesser, BS; Gold, SM; Voskuhl, RR	1
Barkhof, F; Geurts, JJ	1
Suzumura, A	1
Agnati, LF; Fuxe, KG; Goncharova, LB; Tarakanov, AO	1
Campbell, G; Hanson, PS; Lassmann, H; Lax, N; Mahad, DJ; Turnbull, DM; White, K; Ziabreva, I	1
Banker, G; Bourdette, D; Forte, M; Su, KG	1
Bernardi, G; Centonze, D; Furlan, R; Martino, G; Muzio, L; Rossi, S	1
Casaccia, P; Dietz, K; He, Y; Howell, O; Kim, JY; Reynolds, R; Shen, S	1
Carlson, NG; Hill, KE; Redd, JW; Rojas, MA; Rose, JW; Tang, P; Wood, B	1
Battaglia, G; Bicciato, S; Bruno, V; Busceti, C; Di Marco, R; Fallarino, F; Fazio, F; Fioretti, MC; Grohmann, U; Nicoletti, F; Notartomaso, S; Puccetti, P; Vacca, C; Volpi, C	1
Baranzini, SE; Hauser, SL; Khankhanian, P; Matthews, PM; Nelson, SJ; Oksenberg, JR; Okuda, DT; Pelletier, D; Srinivasan, R	1
Domercq, M; Matute, C; Pampliega, O; Rodríguez-Antigüedad, A; Soria, FN; Villoslada, P	1
Bernardi, G; Centonze, D; De Chiara, V; Furlan, R; Lo Giudice, T; Martino, G; Martorana, A; Motta, C; Musella, A; Rossi, S; Studer, V	1
Berman, NE; Buchheit, CL; LeVine, SM; Williams, R	1
Chatterjee, S; Kesavadas, C; Saini, J; Thomas, B	1
Cambron, M; Clinckers, R; D'Haeseleer, M; De Keyser, J; Debruyne, J; Laureys, G	1
Cogo, MG; Frigeni, B; Frigo, M; Fusco, ML; Gardinetti, M	1
Barkhof, F; Geurts, JJ; Inkster, B; Kappos, L; Matthews, PM; Montana, G; Naegelin, Y; Polman, CH; Radue, EW; Strijbis, EM; Uitdehaag, BM; Vounou, M	1
Barabanova, MA; Ivanova, EM; Muzlaev, GG; Petropavlovskaia, TA; Stoianova, OV	1
Kostic, M; Stojanovic, I; Zivkovic, N	1
Ewing, AG; Lapos, JA; Manica, DP	1
Canonico, PL; Comi, C; Lombardi, G; Miglio, G; Monaco, F; Naldi, P	1
Giuliani, F; Imai, Y; Power, C; Takahashi, JL; Yong, VW	1
Archer, T; Beninger, RJ; Kostrzewa, RM; Palomo, T	1
Groom, AJ; Smith, T; Turski, L	1
Floridi, A; Gallai, V; Greco, L; Sarchielli, P	1
ADAMS, JE; BENTINCK, RC; GORDAN, GS; HARPER, HA; HUTCHIN, M	1
Nagelmeier, IE; Pitt, D; Raine, CS; Wilson, HC	1
Ben-Hur, T; Grigoriadis, N; Karussis, D; Milonas, I	1
Hurd, R; Nelson, S; Pelletier, D; Sailasuta, N; Srinivasan, R	1
Kalkers, NF; Killestein, J; Polman, CH	1
Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA	1
Domercq, M; Matute, C; Pérez-Cerdá, F; Ravid, R; Vallejo-Illarramendi, A	1
Domercq, M; Matute, C; Sánchez-Gómez, MV	1
Acheampong, E; Mukhtar, M; Parveen, Z; Pomerantz, RJ	1
Cianfoni, A; Imbesi, SG; Niku, S	1
Bonucci, M; Calabresi, P; Candeliere, A; Chiasserini, D; Di Filippo, M; Mattioni, A; Sarchielli, P; Tenaglia, S	1
Bernardi, G; Centonze, D; Finazzi-Agrò, A; Maccarrone, M; Rossi, S	1
Harzheim, M; Klotz, L; Lutterbey, GG; Schild, HH; Träber, F; Wattjes, MP	1
Capello, E; Cavalla, P; Giordana, MT; Mancardi, GL; Merola, A; Mutani, R; Piacentino, C; Vercellino, M; Votta, B	1
Dove, R; Newcombe, J; Nishizawa, Y; Patel, B; Smith, T; Turski, L; Uddin, A	1
Hatzimanolis, A; Poulopoulou, C	1
Bar-Shir, A; Basso, AS; Costa-Pinto, FA; Engel, Y; Frenkel, D; Gozin, M; Monsonego, A; Petrovic-Stojkovic, S; Puckett, L; Quintana, FJ; Weiner, HL	1
Alferova, VP; Barkhatova, VP; Niiazbekova, AS; Panteleeva, EA; Rebrova, OIu; Zavalishin, IA	1
Butts, BD; Houde, C; Mehmet, H	1
Kempski, OS; Lowitzsch, K; Stover, JF	1
Hokkanen, L; Launes, J; Lindsberg, PJ; Sirén, J; Viinikka, L	1
Gurwitz, D; Kloog, Y	1
Li, SJ; Prost, R; Rand, SD	1
Pitt, D; Raine, CS; Werner, P	3
Barker, GJ; Duncan, JS; McLean, MA; Woermann, FG	1
Barkhatova, BP; Demina, EG; Khaĭdarov, BT; Shavratskiĭ, VKh; Zavalishin, IA	1
Alberdi, E; Domercq, M; Matute, C; Pérez-Cerdá, F; Pérez-Samartín, A; Sánchez-Gómez, MV	1
Hall, SM; Smith, KJ	1

Reviews

30 review(s) available for glutamic acid and Multiple Sclerosis

Article	Year
Function and therapeutic value of astrocytes in neurological diseases. Nature reviews. Drug discovery, 2022, Volume: 21, Issue:5 Topics: Astrocytes; Cell Communication; Glutamic Acid; Humans; Multiple Sclerosis; Nervous System Diseases	2022
The potential roles of amino acids and their major derivatives in the management of multiple sclerosis. Amino acids, 2022, Volume: 54, Issue:6 Topics: Amino Acids; Glutamic Acid; Humans; Multiple Sclerosis; Phenylalanine; Threonine; Tryptophan	2022
Exploring the Role of Neurotransmitters in Multiple Sclerosis: An Expanded Review. ACS chemical neuroscience, 2023, 02-15, Volume: 14, Issue:4 Topics: Glutamic Acid; Humans; Inflammation; Multiple Sclerosis; Neurodegenerative Diseases; Neurotransmitter Agents	2023
Glial Glutamate Transporter-Mediated Plasticity: System x Frontiers in bioscience (Landmark edition), 2023, 03-20, Volume: 28, Issue:3 Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amino Acid Transport System y+; Amyotrophic Lateral Sclerosis; Antioxidants; Cystine; Glioma; Glutamic Acid; Humans; Microglia; Multiple Sclerosis; Parkinson Disease	2023
Smouldering Lesion in MS: Microglia, Lymphocytes and Pathobiochemical Mechanisms. International journal of molecular sciences, 2023, Aug-10, Volume: 24, Issue:16 Topics: Glutamic Acid; Humans; Inflammation; Lymphocytes; Microglia; Multiple Sclerosis; Neurodegenerative Diseases	2023
[The role of glutamate in the pathogenesis of multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2019, Volume: 119, Issue:8 Topics: Demyelinating Diseases; Endothelial Cells; Glutamic Acid; Humans; Multiple Sclerosis; Oligodendroglia	2019
The importance of glutamate in the neuro-endocrinological functions in multiple sclerosis, related to fatigue. Revista de neurologia, 2018, Nov-16, Volume: 67, Issue:10 Topics: Fatigue; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Multiple Sclerosis; Pituitary-Adrenal System	2018
Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease. Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:11 Topics: Animals; Biological Transport; Central Nervous System; Epilepsy; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glutamic Acid; Homeostasis; Humans; Hypoxia; Mice; Multiple Sclerosis; Oxidative Stress; Schizophrenia; Signal Transduction	2014
The role of glutamate and its receptors in multiple sclerosis. Journal of neural transmission (Vienna, Austria : 1996), 2014, Volume: 121, Issue:8 Topics: Animals; Glutamic Acid; Humans; Multiple Sclerosis; Neuroimmunomodulation; Receptors, Glutamate	2014
IL-1β dependent cerebellar synaptopathy in a mouse mode of multiple sclerosis. Cerebellum (London, England), 2015, Volume: 14, Issue:1 Topics: Animals; Cerebellum; Encephalomyelitis, Autoimmune, Experimental; gamma-Aminobutyric Acid; Glutamic Acid; Interleukin-1beta; Mice; Multiple Sclerosis; Synapses; T-Lymphocytes	2015
Albumin and multiple sclerosis. BMC neurology, 2016, Apr-12, Volume: 16 Topics: Albumins; Blood-Brain Barrier; Cytokines; Glutamic Acid; Humans; Microglia; Multiple Sclerosis; Neurons	2016
Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities. The Lancet. Neurology, 2016, Volume: 15, Issue:10 Topics: Biomarkers; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Multiple Sclerosis	2016
Excitotoxins, Mitochondrial and Redox Disturbances in Multiple Sclerosis. International journal of molecular sciences, 2017, Feb-08, Volume: 18, Issue:2 Topics: Animals; Biomarkers; Blood-Brain Barrier; Disease Models, Animal; Disease Progression; Glutamic Acid; Humans; Mitochondria; Multiple Sclerosis; Neurotoxins; Oxidation-Reduction; Oxidative Stress; Receptors, Glutamate	2017
Glutamate, T cells and multiple sclerosis. Journal of neural transmission (Vienna, Austria : 1996), 2017, Volume: 124, Issue:7 Topics: Animals; Glutamic Acid; Humans; Lymphocyte Activation; Multiple Sclerosis; T-Lymphocytes	2017
Grey matter pathology in multiple sclerosis. The Lancet. Neurology, 2008, Volume: 7, Issue:9 Topics: Cerebral Cortex; Encephalitis; Glutamic Acid; Humans; Intercellular Signaling Peptides and Proteins; Meninges; Mitochondria; Multiple Sclerosis; Nerve Degeneration; Neurons	2008
Axonal degeneration in multiple sclerosis: the mitochondrial hypothesis. Current neurology and neuroscience reports, 2009, Volume: 9, Issue:5 Topics: Axonal Transport; Axons; Glutamic Acid; Humans; Mitochondria; Mitochondrial Membranes; Multiple Sclerosis; Nerve Fibers, Myelinated; Nitric Oxide	2009
The link between inflammation, synaptic transmission and neurodegeneration in multiple sclerosis. Cell death and differentiation, 2010, Volume: 17, Issue:7 Topics: Animals; Cytokines; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Inflammation; Multiple Sclerosis; Nerve Degeneration; Synaptic Transmission	2010
Pathogenic implications of iron accumulation in multiple sclerosis. Journal of neurochemistry, 2012, Volume: 120, Issue:1 Topics: Animals; Blood Vessels; Brain Chemistry; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Humans; Iron; Iron, Dietary; Macrophages; Magnetic Resonance Imaging; Microglia; Multiple Sclerosis; Neurodegenerative Diseases; Neurotoxins	2012
White-matter astrocytes, axonal energy metabolism, and axonal degeneration in multiple sclerosis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:3 Topics: Astrocytes; Axons; Brain; Energy Metabolism; Glutamic Acid; Humans; Mitochondria; Multiple Sclerosis; Nerve Degeneration; Phosphocreatine	2012
Glutamate and multiple sclerosis. Current medicinal chemistry, 2012, Volume: 19, Issue:9 Topics: Animals; Central Nervous System; Demyelinating Diseases; Glutamic Acid; Humans; Multiple Sclerosis; Oxidative Stress	2012
Multiple sclerosis and glutamate excitotoxicity. Reviews in the neurosciences, 2013, Volume: 24, Issue:1 Topics: Animals; Central Nervous System; Glutamic Acid; Humans; Multiple Sclerosis; Neurodegenerative Diseases; Receptors, Glutamate	2013
Brain sites of movement disorder: genetic and environmental agents in neurodevelopmental perturbations. Neurotoxicity research, 2003, Volume: 5, Issue:1-2 Topics: Ataxia; Attention Deficit Disorder with Hyperactivity; Environmental Pollutants; Epilepsy; Glutamic Acid; Humans; Infant, Newborn; Iron; Mercury; Movement Disorders; Multiple Sclerosis; Mutagens; Neostriatum; Nerve Growth Factors; Receptors, Dopamine	2003
Axonal damage in multiple sclerosis: a complex issue in a complex disease. Clinical neurology and neurosurgery, 2004, Volume: 106, Issue:3 Topics: Adjuvants, Immunologic; Axons; Brain; Demyelinating Diseases; Diagnosis, Differential; Glutamic Acid; Humans; Interferon-beta; Macrophages; Magnetic Resonance Imaging; Multiple Sclerosis; Myelin Sheath; Nerve Degeneration	2004
Glutamate-mediated glial injury: mechanisms and clinical importance. Glia, 2006, Jan-15, Volume: 53, Issue:2 Topics: Amino Acid Transport System X-AG; Animals; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Multiple Sclerosis; Nervous System Diseases; Neurodegenerative Diseases; Neuroglia; Receptors, Glutamate; Signal Transduction	2006
T-Cells and excitotoxicity: HIV-1 and other neurodegenerative disorders. Neuromolecular medicine, 2005, Volume: 7, Issue:3 Topics: AIDS Dementia Complex; Animals; Brain; CD4-Positive T-Lymphocytes; Excitatory Amino Acids; Glutamic Acid; HIV-1; Humans; Immune Tolerance; Multiple Sclerosis; Neurodegenerative Diseases	2005
The (endo)cannabinoid system in multiple sclerosis and amyotrophic lateral sclerosis. International review of neurobiology, 2007, Volume: 82 Topics: Amyotrophic Lateral Sclerosis; Animals; Cannabinoid Receptor Modulators; Glutamic Acid; Humans; Microglia; Multiple Sclerosis; Neurodegenerative Diseases; Oxidative Stress; Synaptic Transmission	2007
Maturation-dependent sensitivity of oligodendrocyte lineage cells to apoptosis: implications for normal development and disease. Cell death and differentiation, 2008, Volume: 15, Issue:7 Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Brain Diseases; Cell Differentiation; Cell Lineage; Cell Survival; Central Nervous System; Glutamic Acid; Humans; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Reactive Oxygen Species; Schizophrenia	2008
Proton MR spectroscopy of the brain. Neuroimaging clinics of North America, 1999, Volume: 9, Issue:2 Topics: Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Carbon Isotopes; Cerebral Infarction; Demyelinating Diseases; Diagnosis, Differential; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Membrane Lipids; Multiple Sclerosis; Neurotransmitter Agents; Phosphorus Isotopes; Protons; United States; United States Food and Drug Administration	1999
The link between excitotoxic oligodendroglial death and demyelinating diseases. Trends in neurosciences, 2001, Volume: 24, Issue:4 Topics: Animals; Autoimmunity; Cell Death; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; GluK2 Kainate Receptor; Glutamic Acid; Humans; Multiple Sclerosis; Neurotoxins; Oligodendroglia; Optic Nerve; Receptors, AMPA; Receptors, Kainic Acid	2001
Factors directly affecting impulse transmission in inflammatory demyelinating disease: recent advances in our understanding. Current opinion in neurology, 2001, Volume: 14, Issue:3 Topics: Autoantibodies; Axons; Blood-Brain Barrier; Brain; Cytokines; Glutamic Acid; Guillain-Barre Syndrome; Humans; Membrane Potentials; Multiple Sclerosis; Nerve Degeneration; Nitric Oxide; Synaptic Transmission	2001

Trials

3 trial(s) available for glutamic acid and Multiple Sclerosis

Article	Year
Immune modulation and increased neurotrophic factor production in multiple sclerosis patients treated with testosterone. Journal of neuroinflammation, 2008, Jul-31, Volume: 5 Topics: Adult; Animals; Cells, Cultured; Cross-Over Studies; Cytokines; Glutamic Acid; Humans; Immune System; Immunologic Factors; Intercellular Signaling Peptides and Proteins; Lymphocyte Subsets; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Middle Aged; Multiple Sclerosis; Neurons; Testosterone	2008
Glutamate inhibition in MS: the neuroprotective properties of riluzole. Journal of the neurological sciences, 2005, Jun-15, Volume: 233, Issue:1-2 Topics: Adult; Aged; Female; Follow-Up Studies; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Neuroprotective Agents; Riluzole; Spinal Cord	2005
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter. Magnetic resonance in medicine, 2000, Volume: 44, Issue:3 Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phantoms, Imaging; Regression Analysis; Sensitivity and Specificity	2000

Other Studies

72 other study(ies) available for glutamic acid and Multiple Sclerosis

Article	Year
[Prognostic value of cerebrospinal fluid glutamate in multiple sclerosis]. Medicina, 2021, Volume: 81, Issue:5 Topics: Glutamic Acid; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Prognosis	2021
Temporal and spatial evolution of various functional neurons during demyelination induced by cuprizone. Journal of neurophysiology, 2021, 11-01, Volume: 126, Issue:5 Topics: Animals; Astrocytes; Axons; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glutamic Acid; Mice; Monoamine Oxidase Inhibitors; Multiple Sclerosis; Myelin Sheath; Neurons	2021
Neuroprotective Effect of Glatiramer Acetate on Neurofilament Light Chain Leakage and Glutamate Excess in an Animal Model of Multiple Sclerosis. International journal of molecular sciences, 2021, Dec-14, Volume: 22, Issue:24 Topics: Animals; Axons; Cerebrospinal Fluid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Glatiramer Acetate; Glutamic Acid; Intermediate Filaments; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Peptides	2021
MS-Driven Metabolic Alterations Are Recapitulated in iPSC-Derived Astrocytes. Annals of neurology, 2022, Volume: 91, Issue:5 Topics: Animals; Astrocytes; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Mice; Mitochondria; Multiple Sclerosis	2022
Cerebrospinal fluid, brain, and spinal cord levels of L-aspartate signal excitatory neurotransmission abnormalities in multiple sclerosis patients and experimental autoimmune encephalomyelitis mouse model. Journal of neurochemistry, 2023, Volume: 166, Issue:3 Topics: Animals; Aspartic Acid; Brain; Cytokines; D-Aspartic Acid; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acids; Glutamic Acid; Mice; Multiple Sclerosis; Spinal Cord; Synaptic Transmission	2023
MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis. Brain : a journal of neurology, 2019, 10-01, Volume: 142, Issue:10 Topics: Animals; Axons; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Humans; Leukocytes, Mononuclear; Mice; MicroRNAs; Multiple Sclerosis; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Spinal Cord	2019
Altered hypothalamic metabolism in early multiple sclerosis - MR spectroscopy study. Journal of the neurological sciences, 2019, Dec-15, Volume: 407 Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Hypothalamus; Inositol; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis; Young Adult	2019
β1-Integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells. The Journal of clinical investigation, 2020, 02-03, Volume: 130, Issue:2 Topics: Animals; Cell Communication; Glutamic Acid; Humans; Integrin beta1; Kv1.3 Potassium Channel; Mice; Mice, Knockout; Multiple Sclerosis; Signal Transduction; SNARE Proteins; Th17 Cells; Vascular Cell Adhesion Molecule-1	2020
Glutamate and Nitric Oxide as biomarkers for disease activity in patients with multiple sclerosis. Multiple sclerosis and related disorders, 2020, Volume: 38 Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Disease Progression; Female; Glutamic Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nitric Oxide; Recurrence; Young Adult	2020
Guggulsterone ameliorates ethidium bromide-induced experimental model of multiple sclerosis via restoration of behavioral, molecular, neurochemical and morphological alterations in rat brain. Metabolic brain disease, 2021, Volume: 36, Issue:5 Topics: Acetylcholinesterase; Animals; Brain; Disease Models, Animal; Dopamine; Ethidium; Female; Glutamic Acid; Male; Maze Learning; Multiple Sclerosis; Neuroprotective Agents; Oxidative Stress; PPAR gamma; Pregnenediones; Rats; Rats, Wistar; STAT3 Transcription Factor	2021
Altered in vivo brain GABA and glutamate levels are associated with multiple sclerosis central fatigue. European journal of radiology, 2021, Volume: 137 Topics: Brain; Fatigue; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Multiple Sclerosis	2021
Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2018, Volume: 24, Issue:4 Topics: Adult; Brain; Choline; Diffusion Tensor Imaging; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Young Adult	2018
Serum Glutamate Is a Predictor for the Diagnosis of Multiple Sclerosis. TheScientificWorldJournal, 2017, Volume: 2017 Topics: Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Humans; Multiple Sclerosis; ROC Curve	2017
Sphingomimetic multiple sclerosis drug FTY720 activates vesicular synaptobrevin and augments neuroendocrine secretion. Scientific reports, 2017, 07-20, Volume: 7, Issue:1 Topics: Animals; Cytosol; Excitatory Postsynaptic Potentials; Exocytosis; Fingolimod Hydrochloride; Glutamic Acid; Hippocampus; Male; Multiple Sclerosis; Neurons; Neurosecretory Systems; R-SNARE Proteins; Rats, Wistar; SNARE Proteins; Sphingosine; Synaptic Vesicles; Synaptosomes	2017
Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis. PloS one, 2017, Volume: 12, Issue:8 Topics: Animals; Basal Ganglia; Cell Line; Corpus Callosum; Crotonates; Disease Models, Animal; Drug Evaluation, Preclinical; Excitatory Amino Acid Agents; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hydroxybutyrates; Mesocricetus; Mice; Multiple Sclerosis; Myelitis; Nitriles; Thalamus; Toluidines	2017
Increased glutamate and deep brain atrophy can predict the severity of multiple sclerosis. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2019, Volume: 163, Issue:1 Topics: Adult; Aspartic Acid; Atrophy; Disease Progression; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Predictive Value of Tests; Severity of Illness Index; Thalamus; Young Adult	2019
Reduced Microglial Activity and Enhanced Glutamate Transmission in the Basolateral Amygdala in Early CNS Autoimmunity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 10-17, Volume: 38, Issue:42 Topics: Animals; Basolateral Nuclear Complex; Complement System Proteins; Cytokines; Dendritic Spines; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Mice, Inbred C57BL; Microglia; Miniature Postsynaptic Potentials; Multiple Sclerosis; Neurons; Receptors, AMPA; Synaptic Transmission	2018
Glutamate-sensitive imaging and evaluation of cognitive impairment in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2019, Volume: 25, Issue:12 Topics: Adult; Cerebral Cortex; Cognitive Dysfunction; Female; Glutamic Acid; Gray Matter; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; White Matter	2019
Safranal Attenuates Excitotoxin-Induced Oxidative OLN-93 Cells Injury. Drug research, 2019, Volume: 69, Issue:6 Topics: Animals; Antioxidants; Cell Survival; Cyclohexenes; Glutamic Acid; Multiple Sclerosis; Neurotoxins; Oligodendroglia; Oxidative Stress; Quinolinic Acid; Rats; Reactive Oxygen Species; Terpenes	2019
[Glutamate, hypothalamus-hypophysis-adrenal axis and clinical manifestations in multiple sclerosis]. Revista de neurologia, 2019, 02-01, Volume: 68, Issue:3 Topics: Fatigue; Glutamic Acid; Humans; Hypothalamus; Multiple Sclerosis; Pituitary Gland	2019
Peripheral T cells from multiple sclerosis patients trigger synaptotoxic alterations in central neurons. Neuropathology and applied neurobiology, 2020, Volume: 46, Issue:2 Topics: Adult; Animals; Brain; Female; Glutamic Acid; Humans; Male; Mice, Inbred C57BL; Multiple Sclerosis; Neurons; Synapses; Synaptic Transmission; T-Lymphocytes	2020
Increased concentrations of glutamate and glutamine in normal-appearing white matter of patients with multiple sclerosis and normal MR imaging brain scans. PloS one, 2013, Volume: 8, Issue:4 Topics: Adult; Aged; Aspartic Acid; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis	2013
Regional regulation of glutamate signaling during cuprizone-induced demyelination in the brain. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2013, Volume: 195, Issue:5 Topics: Amino Acid Transport System X-AG; Animals; Blotting, Western; Brain; Cells, Cultured; Chelating Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Fluorescent Antibody Technique; Glutamic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Protein Array Analysis; Real-Time Polymerase Chain Reaction; Receptors, Glutamate; Signal Transduction	2013
HPA axis activity in multiple sclerosis correlates with disease severity, lesion type and gene expression in normal-appearing white matter. Acta neuropathologica, 2013, Volume: 126, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Cerebrospinal Fluid; Corticotropin-Releasing Hormone; Female; Gene Expression; Glutamic Acid; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Mood Disorders; Multiple Sclerosis; Nerve Degeneration; Nerve Fibers, Myelinated; Neurofilament Proteins; Neurons; Pituitary-Adrenal System; Severity of Illness Index; tau Proteins; Tissue Banks; Transcriptome	2013
Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis. Neurobiology of disease, 2013, Volume: 59 Topics: Amyloid beta-Protein Precursor; Animals; Brain; Brain Infarction; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Glutamic Acid; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neurons; Peptide Fragments; Phosphopyruvate Hydratase; Time Factors	2013
Small molecule glutaminase inhibitors block glutamate release from stimulated microglia. Biochemical and biophysical research communications, 2014, Jan-03, Volume: 443, Issue:1 Topics: AIDS Dementia Complex; Animals; Biological Assay; Brain Ischemia; Cells, Cultured; Drug Evaluation, Preclinical; Glutamic Acid; Glutaminase; Mice; Microglia; Multiple Sclerosis; Neuroprotective Agents; Small Molecule Libraries; Tetradecanoylphorbol Acetate; Toll-Like Receptors; Tumor Necrosis Factor-alpha	2014
IL-17 and glutamate excitotoxicity in the pathogenesis of multiple sclerosis. Scandinavian journal of immunology, 2014, Volume: 79, Issue:3 Topics: Adolescent; Adult; Aged; Blood-Brain Barrier; Female; Glutamic Acid; Humans; Inflammation; Interleukin-17; Male; Middle Aged; Multiple Sclerosis; Neutrophils; Th17 Cells; Young Adult	2014
In vivo evidence of glutamate toxicity in multiple sclerosis. Annals of neurology, 2014, Volume: 76, Issue:2 Topics: Adult; Aspartic Acid; Brain; Female; Follow-Up Studies; Glutamic Acid; History, Ancient; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis	2014
An integrated metabolomics approach for the research of new cerebrospinal fluid biomarkers of multiple sclerosis. Molecular bioSystems, 2015, Volume: 11, Issue:6 Topics: Biomarkers; Carnitine; Glutamic Acid; Humans; Lipids; Metabolome; Metabolomics; Multiple Sclerosis	2015
Reduced gamma-aminobutyric acid concentration is associated with physical disability in progressive multiple sclerosis. Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 9 Topics: Adult; Aspartic Acid; Brain; Disability Evaluation; Disabled Persons; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Neuropsychological Tests; Severity of Illness Index	2015
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors. Nature communications, 2015, Oct-06, Volume: 6 Topics: Action Potentials; Adult; Animals; Axons; Brain; Female; Glutamic Acid; Humans; Immunohistochemistry; Male; Microscopy, Electron; Middle Aged; Multiple Sclerosis; Myelin Sheath; Neurons; Oligodendroglia; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Regeneration; Stem Cells; Vesicular Glutamate Transport Protein 2	2015
In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity. Journal of neurochemistry, 2016, Volume: 136, Issue:5 Topics: Animals; Brain; Cell Death; Cells, Cultured; Glutamic Acid; Immunomodulation; Kainic Acid; Multiple Sclerosis; Neurons; Neuroprotective Agents; Signal Transduction; Up-Regulation	2016
Reproducibility measurement of glutathione, GABA, and glutamate: Towards in vivo neurochemical profiling of multiple sclerosis with MR spectroscopy at 7T. Journal of magnetic resonance imaging : JMRI, 2017, Volume: 45, Issue:1 Topics: Adult; Biomarkers; Brain; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Imaging; Male; Molecular Imaging; Multiple Sclerosis; Neurotransmitter Agents; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity	2017
IL-17 signalling in astrocytes promotes glutamate excitotoxicity: Indications for the link between inflammatory and neurodegenerative events in multiple sclerosis. Multiple sclerosis and related disorders, 2017, Volume: 11 Topics: Animals; Astrocytes; Calcium; Cations, Divalent; Cells, Cultured; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Multiple Sclerosis; Nerve Degeneration; Rats; Recombinant Proteins	2017
GABA and glutamate levels correlate with MTR and clinical disability: Insights from multiple sclerosis. NeuroImage, 2017, 08-15, Volume: 157 Topics: Adult; Disabled Persons; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gray Matter; Humans; Male; Middle Aged; Multiple Sclerosis; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; White Matter	2017
[Therapeutic strategy against multiple sclerosis]. Rinsho shinkeigaku = Clinical neurology, 2008, Volume: 48, Issue:11 Topics: Animals; Aptamers, Nucleotide; Autoimmunity; Axons; Cytokines; Enzyme Inhibitors; Gap Junctions; Glutamic Acid; Glutaminase; Humans; Interferon-beta; Macrophages; Microglia; Midkine; Multiple Sclerosis; Nerve Degeneration; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells	2008
Possible role of receptor heteromers in multiple sclerosis. Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:8 Topics: Animals; Glutamic Acid; Humans; Microglia; Models, Neurological; Multiple Sclerosis; Protein Multimerization; Receptors, Cytokine; Receptors, Glutamate	2009
Mitochondrial changes within axons in multiple sclerosis. Brain : a journal of neurology, 2009, Volume: 132, Issue:Pt 5 Topics: Adult; Aged; Aged, 80 and over; Animals; Autopsy; Axons; Blotting, Western; Brain; Cells, Cultured; Chronic Disease; Electron Transport Complex II; Electron Transport Complex IV; Female; Glutamic Acid; Humans; Immunohistochemistry; Male; Mice; Microscopy, Electron; Middle Aged; Mitochondria; Multiple Sclerosis; Sodium Azide; Spinal Cord	2009
HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Nature neuroscience, 2010, Volume: 13, Issue:2 Topics: Active Transport, Cell Nucleus; Animals; Axons; Brain; Cell Nucleus; Cells, Cultured; Cuprizone; Demyelinating Diseases; Exportin 1 Protein; Glutamic Acid; Histone Deacetylase 1; Humans; Karyopherins; Mice; Mice, Inbred C57BL; Mitochondria; Multiple Sclerosis; Neurons; Rats; Receptors, Cytoplasmic and Nuclear; Time Factors; Tumor Necrosis Factor-alpha	2010
Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death. Journal of neuroinflammation, 2010, Apr-13, Volume: 7 Topics: Animals; Cardiovirus Infections; Cell Death; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Demyelinating Diseases; Fluorescent Antibody Technique; Glutamic Acid; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Microscopy, Confocal; Multiple Sclerosis; Oligodendroglia; Organ Culture Techniques; Spinal Cord; Theilovirus	2010
Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation. Nature medicine, 2010, Volume: 16, Issue:8 Topics: Adaptive Immunity; Animals; Cell Differentiation; Cytokines; Dendritic Cells; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Glutamic Acid; Mice; Mice, Knockout; Multiple Sclerosis; Nerve Degeneration; Neuroimmunomodulation; Receptors, Metabotropic Glutamate; Signal Transduction; T-Lymphocytes, Helper-Inducer	2010
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain : a journal of neurology, 2010, Volume: 133, Issue:9 Topics: Adult; Aspartic Acid; Brain; Computer Simulation; Female; Follow-Up Studies; Gene Frequency; Genetic Variation; Genome-Wide Association Study; Genotype; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Models, Genetic; Multiple Sclerosis; Oxidoreductases Acting on Sulfur Group Donors; Polymorphism, Single Nucleotide; Statistics as Topic; Sulfatases	2010
Increased expression of cystine/glutamate antiporter in multiple sclerosis. Journal of neuroinflammation, 2011, Jun-03, Volume: 8 Topics: Adult; Aged; Aged, 80 and over; Amino Acid Transport System y+; Amino Acid Transport Systems, Acidic; Animals; Cell Line; Cystine; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamic Acid; Glutathione; Homeostasis; Humans; Inflammation; Male; Middle Aged; Multiple Sclerosis; Optic Nerve; Rats; Rats, Inbred Lew; Spinal Cord; Young Adult	2011
Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis. British journal of pharmacology, 2012, Volume: 165, Issue:4 Topics: Animals; Dendritic Spines; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; Fingolimod Hydrochloride; Glutamic Acid; Glycoproteins; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Propylene Glycols; Sphingosine; Synapses; Synaptic Transmission	2012
Conventional and advanced magnetic resonance imaging in tumefactive demyelination. Acta radiologica (Stockholm, Sweden : 1987), 2011, Dec-01, Volume: 52, Issue:10 Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Contrast Media; Demyelinating Diseases; Diffusion Magnetic Resonance Imaging; Female; Follow-Up Studies; Gadolinium DTPA; Glutamic Acid; Glutamine; Humans; Image Enhancement; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Young Adult	2011
Glutamate gene polymorphisms predict brain volumes in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2013, Volume: 19, Issue:3 Topics: Adult; Aged; Brain Chemistry; Endophenotypes; Female; Genotyping Techniques; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Models, Statistical; Multiple Sclerosis; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Young Adult	2013
[Amino acids content in the blood serum of patients with multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:6 Topics: Adult; Aspartic Acid; Chromatography, Ion Exchange; Female; Glutamic Acid; Glycine; Humans; Male; Multiple Sclerosis; Severity of Illness Index	2012
Dual fluorescence and electrochemical detection on an electrophoresis microchip. Analytical chemistry, 2002, Jul-15, Volume: 74, Issue:14 Topics: 4-Chloro-7-nitrobenzofurazan; Arginine; Catechols; Dopamine; Electrochemistry; Electrophoresis, Capillary; Fluorescence; Glutamic Acid; Humans; Indicators and Reagents; Multiple Sclerosis; Phenylalanine	2002
Abnormal response to glutamate of T lymphocytes from multiple sclerosis patients. Neuroscience letters, 2003, Apr-03, Volume: 340, Issue:1 Topics: Adult; Female; Glutamic Acid; Humans; Male; Multiple Sclerosis; Statistics, Nonparametric; T-Lymphocytes	2003
Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity. Annals of neurology, 2003, Volume: 53, Issue:5 Topics: Apoptosis; Cell Culture Techniques; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-1; Microglia; Multiple Sclerosis; Oligodendroglia; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Tumor Necrosis Factor-alpha	2003
Multiple sclerosis and glutamate. Annals of the New York Academy of Sciences, 2003, Volume: 993 Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Receptors, AMPA; Spinal Cord	2003
Excitatory amino acids and multiple sclerosis: evidence from cerebrospinal fluid. Archives of neurology, 2003, Volume: 60, Issue:8 Topics: Adult; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Disability Evaluation; Gadolinium DTPA; Glutamic Acid; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Multiple Sclerosis; Spinal Cord	2003
Cerebral metabolism of glutamic acid in multiple sclerosis. Neurology, 1955, Volume: 5, Issue:2 Topics: Brain; Glutamates; Glutamic Acid; Humans; Multiple Sclerosis	1955
Glutamate uptake by oligodendrocytes: Implications for excitotoxicity in multiple sclerosis. Neurology, 2003, Oct-28, Volume: 61, Issue:8 Topics: Adult; Aged; Astrocytes; Autoradiography; Biological Transport; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Gene Expression; Glutamic Acid; Humans; In Situ Hybridization; Male; Middle Aged; Multiple Sclerosis; Neurotoxins; Oligodendroglia; RNA, Messenger; Spinal Cord; Tritium; Tumor Necrosis Factor-alpha	2003
Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 5 Topics: Acute Disease; Adult; Brain; Choline; Chronic Disease; Female; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis	2005
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase	2006
Increased expression and function of glutamate transporters in multiple sclerosis. Neurobiology of disease, 2006, Volume: 21, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nerve Degeneration; Neurotoxins; Oligodendroglia; Oligonucleotide Array Sequence Analysis; Optic Nerve; RNA, Messenger	2006
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy. AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases; Diagnosis, Differential; Echo-Planar Imaging; Female; Glutamic Acid; Humans; Lactic Acid; Male; Middle Aged; Multiple Sclerosis; Protons	2007
Expression of ionotropic glutamate receptor GLUR3 and effects of glutamate on MBP- and MOG-specific lymphocyte activation and chemotactic migration in multiple sclerosis patients. Journal of neuroimmunology, 2007, Volume: 188, Issue:1-2 Topics: Adult; Case-Control Studies; Cell Movement; Chemokine CCL5; Chemokine CXCL12; Chemokines, CXC; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Drug Interactions; Female; Gene Expression Regulation; Glutamic Acid; Humans; Lymphocytes; Magnetic Resonance Imaging; Male; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Receptors, AMPA	2007
Axonal damage but no increased glial cell activity in the normal-appearing white matter of patients with clinically isolated syndromes suggestive of multiple sclerosis using high-field magnetic resonance spectroscopy. AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:8 Topics: Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Neuroglia; Osmolar Concentration	2007
Altered glutamate reuptake in relapsing-remitting and secondary progressive multiple sclerosis cortex: correlation with microglia infiltration, demyelination, and neuronal and synaptic damage. Journal of neuropathology and experimental neurology, 2007, Volume: 66, Issue:8 Topics: Adult; Aged; Cerebral Cortex; Demyelinating Diseases; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glial Fibrillary Acidic Protein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Microglia; Middle Aged; Multiple Sclerosis; Neurons; Postmortem Changes; Synapses	2007
Glutamate receptor expression in multiple sclerosis lesions. Brain pathology (Zurich, Switzerland), 2008, Volume: 18, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Central Nervous System; Excitatory Amino Acid Transporter 3; Female; Gliosis; Glutamic Acid; Humans; Macrophages; Male; Middle Aged; Multiple Sclerosis; Nerve Fibers, Myelinated; Neuroglia; Neurotoxins; Oligodendroglia; Protein Subunits; Receptors, AMPA; Receptors, Kainic Acid; Vesicular Glutamate Transport Proteins	2008
Expression of ionotropic glutamate receptor GLUR3 and effects of glutamate on MBP- and MOG-specific lymphocyte activation and chemotactic migration in multiple sclerosis patients. Journal of neuroimmunology, 2008, Volume: 194, Issue:1-2 Topics: Chemotaxis, Leukocyte; Culture Media; DNA Primers; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Humans; Lymphocyte Activation; Multiple Sclerosis; Polymerase Chain Reaction; Receptors, AMPA; Receptors, Metabotropic Glutamate; Research Design; RNA, Messenger	2008
Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis. The Journal of clinical investigation, 2008, Volume: 118, Issue:4 Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Axons; B-Lymphocytes; CD11b Antigen; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Disease Progression; Fullerenes; Glutamic Acid; Memory; Mice; Molecular Structure; Multiple Sclerosis; Oxidative Stress; T-Lymphocytes	2008
[Neurotransmission mechanism of movement disorders in multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2007, Volume: 107, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Disease Progression; Female; Glutamic Acid; Humans; Male; Middle Aged; Motor Activity; Movement Disorders; Multiple Sclerosis; Neuromuscular Junction; Severity of Illness Index; Synaptic Transmission	2007
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. Neuroscience letters, 1997, Nov-28, Volume: 238, Issue:1-2 Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Epilepsy; Female; Glutamic Acid; Humans; Hypoxanthine; L-Lactate Dehydrogenase; Lactic Acid; Male; Meningitis, Viral; Middle Aged; Multiple Sclerosis; Serum Albumin; Spinal Cord Diseases; Uric Acid; Xanthine	1997
Does glutamate mediate brain damage in acute encephalitis? Neuroreport, 1998, Mar-09, Volume: 9, Issue:4 Topics: Adult; Aged; Amino Acids; Brain; Cerebral Infarction; Encephalitis; Encephalitis, Viral; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Multiple Sclerosis; Multivariate Analysis; Neurons; Reference Values; Taurine	1998
Peroxynitrite generation might explain elevated glutamate and aspartate levels in multiple sclerosis cerebrospinal fluid. European journal of clinical investigation, 1998, Volume: 28, Issue:9 Topics: Animals; Aspartic Acid; Glutamic Acid; Humans; Models, Biological; Multiple Sclerosis; Neurodegenerative Diseases; Nitrates; Nitric Oxide; Receptors, N-Methyl-D-Aspartate	1998
Glutamate excitotoxicity in a model of multiple sclerosis. Nature medicine, 2000, Volume: 6, Issue:1 Topics: Animals; Axons; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred Strains; Multiple Sclerosis; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; T-Lymphocytes	2000
Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis? Journal of neural transmission. Supplementum, 2000, Issue:60 Topics: Animals; Axons; Cell Death; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutaminase; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Myelitis; Neuroprotective Agents; Neurotoxins; Oligodendroglia; Quinoxalines; Receptors, AMPA	2000
[Biochemical mechanisms of impaired neuroimmune interaction in multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2000, Volume: 100, Issue:11 Topics: Adult; Aspartic Acid; Biomarkers; Brain; Cell Death; Female; Glutamic Acid; Humans; Interferon-alpha; Interferon-gamma; Male; Multiple Sclerosis; Oligodendroglia; T-Lymphocytes, Regulatory; Time Factors; Tumor Necrosis Factor-alpha	2000
Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Annals of neurology, 2001, Volume: 50, Issue:2 Topics: Adult; Aged; Axons; Brain; Female; Glutamic Acid; Humans; Immunohistochemistry; Male; Middle Aged; Multiple Sclerosis; Oligodendroglia	2001