glutamic acid has been researched along with Motor Neuron Disease in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 15 (50.00) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grieb, P; Matyja, E; Nagańska, E; Rafałowska, J; Taraszewska, A | 1 |
| Harwood, CA; McDermott, CJ; Shaw, PJ | 1 |
| Brunet, N; Calderó, J; Esquerda, JE; Tarabal, O | 1 |
| Amalric, M; Blobaum, AL; Bode, J; Bridges, TM; Bubser, M; Conn, PJ; Daniels, JS; Dickerson, JW; Engers, DW; Hopkins, CR; Italiano, K; Jadhav, S; Jones, CK; Lindsley, CW; Morrison, RD; Niswender, CM; Thompson, AD; Turle-Lorenzo, N | 1 |
| Ankulu, M; Aparna, N; Khandare, AL | 1 |
| Alcazar, A; Alvarez-Cermeño, JC; Cid, C; Regidor, I; Salinas, M | 1 |
| Angelov, DN; Guntinas-Lichius, O; Kipnis, J; Lenzen, M; Ludolph, A; Neiss, WF; Reuter, A; Schori, H; Schwartz, M; Tomov, TL; Waibel, S; Yoles, E | 1 |
| Aoyagi, J; Ichikawa, Y; Igarashi, O; Ikeda, K; Iwasaki, Y; Kinoshita, M; Konno, S | 1 |
| Boulis, NM; Garrity-Moses, ME; Liu, J; Tanase, D; Teng, Q | 1 |
| Haque, A; Khan, JK; Kuo, YH; Lambein, F | 1 |
| Forrest, V; Ince, PG; Richardson, JP; Shaw, PJ; Wastell, HJ | 1 |
| Kuncl, RW; Rothstein, JD | 1 |
| Battaglioli, G; Martin, DL; Messer, A; Plummer, J | 1 |
| Andjus, PR; Cherubini, E; Stevic-Marinkovic, Z | 1 |
| Maruri, A; Olivera, S; Rodríguez-Ithurralde, D; Vincent, O | 1 |
| Ince, PG; Lowe, J; Shaw, PJ | 1 |
| Babu, GN; Bawari, M; Kalita, J; Mathur, VN; Misra, UK | 1 |
| Miller, RG | 1 |
| Shaw, PJ | 2 |
| Ludolph, AC; Münch, C | 1 |
| Kruman, II; Mattson, MP; Pedersen, WA; Springer, JE | 1 |
| Abe, K; Kashihara, K; Manabe, Y; Shiro, Y; Wang, JM; Warita, H | 1 |
| Akaike, A; Honda, K; Inoue, R; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Andreassen, OA; Beal, MF; Bogdanov, MB; Dedeoglu, A; Ferrante, KL; Jenkins, BG; Kaddurah-Daouk, R | 1 |
| Bastone, A; Bigini, P; Mennini, T | 1 |
| Eisen, A; Weber, M | 1 |
| Han, JS; Tang, XQ; Wan, Y; Wang, Y | 1 |
| Banner, SJ; Cookson, MR; Fray, AE; Ince, PG; Shaw, PJ; Steward, M | 1 |
| Andersen, PM; Goldsteins, G; Koistinaho, J; Marklund, SL; Oja, SS; Tikka, TM; Vartiainen, NE | 1 |
8 review(s) available for glutamic acid and Motor Neuron Disease
| Article | Year |
|---|---|
Physical activity as an exogenous risk factor in motor neuron disease (MND): a review of the evidence.
Topics: Age of Onset; Animals; Genetic Predisposition to Disease; Glutamic Acid; Humans; Motor Activity; Motor Neuron Disease; Nerve Growth Factors; Oxidative Stress; Reproducibility of Results; Risk Factors; Sports | 2009 |
Role of glutamate and nitric oxide in onset of motor neuron degeneration in neurolathyrism.
Topics: Animals; Estrogens; Glutamate-Cysteine Ligase; Glutamic Acid; Humans; Lathyrism; Mitochondria; Motor Cortex; Motor Neuron Disease; Motor Neurons; Nerve Degeneration; Nitric Oxide; Vascular Endothelial Growth Factor A | 2013 |
Amyotrophic lateral sclerosis: current issues in classification, pathogenesis and molecular pathology.
Topics: Amyotrophic Lateral Sclerosis; Animals; Diagnosis, Differential; Free Radicals; Glutamic Acid; Humans; Mice; Mice, Transgenic; Motor Neuron Disease; Ubiquitins | 1998 |
Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases.
Topics: Acetates; Adolescent; Adult; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Guidelines as Topic; Humans; Infant; Insulin-Like Growth Factor I; Male; Mice; Middle Aged; Motor Neuron Disease; Muscular Atrophy, Spinal; Nerve Growth Factors; Outcome Assessment, Health Care; Postpoliomyelitis Syndrome; Riluzole | 1999 |
Motor neurone disease.
Topics: Clinical Trials as Topic; Glutamic Acid; Humans; Motor Neuron Disease; Nerve Degeneration; Oxidative Stress | 1999 |
Neurotoxic mechanisms of degeneration in motor neuron diseases.
Topics: Excitatory Amino Acid Agents; Glutamic Acid; Humans; Mitochondria; Motor Neuron Disease; Neurotoxins; Receptors, Glutamate | 1999 |
Calcium, glutamate, and amyotrophic lateral sclerosis: more evidence but no certainties.
Topics: Calcium; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Motor Neuron Disease; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter | 1999 |
Neurophysiological evaluation of cortical function in the early diagnosis of ALS.
Topics: Anterior Horn Cells; Electroencephalography; Electromyography; Glutamic Acid; Humans; Interneurons; Motor Neuron Disease; Motor Neurons; Muscle, Skeletal; Synaptic Transmission | 2000 |
22 other study(ies) available for glutamic acid and Motor Neuron Disease
| Article | Year |
|---|---|
CDP-choline protects motor neurons against apoptotic changes in a model of chronic glutamate excitotoxicity in vitro.
Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Regulatory Proteins; Cytidine Diphosphate Choline; Glutamic Acid; In Vitro Techniques; Motor Neuron Disease; Nerve Degeneration; Neuroglia; Neurotoxins; Rats; Spinal Cord | 2008 |
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
Topics: Animals; Calcium Signaling; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Malonates; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Organ Culture Techniques; Propionates; Riluzole; Spinal Cord | 2009 |
The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Brain; Calcium Signaling; Catalepsy; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Haloperidol; HEK293 Cells; Humans; Levodopa; Male; Monoamine Oxidase; Motor Neuron Disease; Oxidopamine; Parkinson Disease; Picolinic Acids; Protein Binding; Psychomotor Performance; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Substantia Nigra; Thallium; Transfection; Triazoles; Tyrosine 3-Monooxygenase | 2012 |
Low concentrations of glutamate induce apoptosis in cultured neurons: implications for amyotrophic lateral sclerosis.
Topics: Aged; Apoptosis; Cells, Cultured; Female; Glutamic Acid; Headache; Humans; Immunoglobulin G; Male; Models, Biological; Motor Neuron Disease; Neurons; Neurotoxins; Reference Values; Serum Albumin | 2003 |
Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis.
Topics: Acute Disease; Amyotrophic Lateral Sclerosis; Animals; Axotomy; Cell Death; Chronic Disease; Disease Models, Animal; Facial Nerve; Female; Glatiramer Acetate; Glutamic Acid; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Neuron Disease; Motor Neurons; Nerve Degeneration; Peptides; Superoxide Dismutase; Superoxide Dismutase-1; Vaccines | 2003 |
Temocapril prevents motor neuron damage and upregulation of cyclooxygenase-II in glutamate-induced neurotoxicity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Death; Choline O-Acetyltransferase; Cyclooxygenase 2; Glutamic Acid; Isoenzymes; Motor Neuron Disease; Motor Neurons; Organ Culture Techniques; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Thiazepines; Up-Regulation | 2003 |
Neuroprotective adeno-associated virus Bcl-xL gene transfer in models of motor neuron disease.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; bcl-X Protein; Blotting, Western; Caspase 3; Caspases; Cell Count; Cells, Cultured; Dependovirus; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Gene Expression Regulation; Gene Transfer Techniques; Genetic Vectors; Glutamic Acid; Green Fluorescent Proteins; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Motor Neuron Disease; Neuroblastoma; Rats; Rats, Sprague-Dawley; Time Factors; Transfection | 2005 |
Inhibitory and excitatory amino acids in cerebrospinal fluid of neurolathyrism patients, a highly prevalent motorneurone disease.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Eating; Excitatory Amino Acids; Fabaceae; Glutamic Acid; Glycine; Humans; Isoleucine; Middle Aged; Motor Neuron Disease; Neurotoxins; Plants, Medicinal; Taurine; Threonine | 1995 |
CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients.
Topics: Adult; Aged; Amino Acids; Analysis of Variance; Case-Control Studies; Female; Glutamic Acid; Humans; Male; Middle Aged; Motor Neuron Disease | 1995 |
Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity.
Topics: Animals; Cells, Cultured; Chronic Disease; Drug Resistance; Glutamic Acid; Motor Neuron Disease; Motor Neurons; Neuroprotective Agents; Rats | 1995 |
Synaptosomal glutamate uptake declines progressively in the spinal cord of a mutant mouse with motor neuron disease.
Topics: Animals; Corpus Striatum; Glutamates; Glutamic Acid; Mice; Mice, Mutant Strains; Motor Neuron Disease; Spinal Cord; Synaptosomes | 1993 |
Immunoglobulins from motoneurone disease patients enhance glutamate release from rat hippocampal neurones in culture.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Electric Stimulation; Electrophysiology; Female; Glutamic Acid; Hippocampus; Humans; Immunoglobulins; Male; Membrane Potentials; Middle Aged; Motor Neuron Disease; Neurons; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Synapses | 1997 |
In vivo and in vitro studies of glycine- and glutamate-evoked acetylcholinesterase release from spinal motor neurones: implications for amyotrophic lateral sclerosis/motor neurone disease pathogenesis.
Topics: Acetylcholinesterase; Amyotrophic Lateral Sclerosis; Animals; Calcium; Glutamic Acid; Glycine; Histocytochemistry; Male; Mice; Motor Neuron Disease; Motor Neurons; Receptors, AMPA; Spinal Cord | 1997 |
Blood glutamate levels in patients with motor neuron disease.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Bulbar Palsy, Progressive; Female; Glutamic Acid; Humans; Male; Middle Aged; Motor Neuron Disease | 1998 |
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Calcium; Cells, Cultured; Cyclic N-Oxides; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Free Radicals; Glutamic Acid; Homeostasis; Humans; Imidazoles; Lipid Peroxidation; Mice; Mice, Transgenic; Mitochondria; Motor Neuron Disease; Motor Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Oxidative Stress; Rhodamine 123; Spinal Cord; Superoxide Dismutase; Superoxides; Vitamin E | 1999 |
Glutamate enhances DNA fragmentation in cultured spinal motor neurons of rat.
Topics: Animals; Animals, Newborn; Cell Count; Cells, Cultured; Disease Models, Animal; DNA Fragmentation; Glutamic Acid; In Situ Nick-End Labeling; Motor Neuron Disease; Motor Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases | 2001 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Body Weight; Brain Chemistry; Creatine; Dicarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Microdialysis; Motor Activity; Motor Neuron Disease; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Oxidative Stress; Psychomotor Performance; Pyrrolidines; Superoxide Dismutase | 2001 |
Glutamate transporters in the spinal cord of the wobbler mouse.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Carrier Proteins; Choline O-Acetyltransferase; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Glial Fibrillary Acidic Protein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Motor Neuron Disease; Muscle, Skeletal; Neuroglia; Neurons; Spinal Cord; Symporters | 2001 |
Adenovirus-mediated GDNF protects cultured motoneurons from glutamate injury.
Topics: Adenoviridae; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fetus; Gene Expression Regulation, Viral; Genes, Reporter; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Motor Neuron Disease; Motor Neurons; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Rats; RNA, Messenger | 2001 |
The expression of the glutamate re-uptake transporter excitatory amino acid transporter 1 (EAAT1) in the normal human CNS and in motor neurone disease: an immunohistochemical study.
Topics: Aged; Animals; Antibody Specificity; Astrocytes; Brain; Central Nervous System; Cervical Vertebrae; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Gene Expression; Glutamic Acid; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Middle Aged; Motor Cortex; Motor Neuron Disease; Neurons; Spinal Cord | 2002 |
Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease.
Topics: Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Apoptosis; Cells, Cultured; Cerebrospinal Fluid Proteins; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Microglia; Middle Aged; Minocycline; Motor Neuron Disease; Motor Neurons; Mutation; Neuroprotective Agents; Neurotoxins; Rats; Spinal Cord; Superoxide Dismutase | 2002 |