glutamic acid has been researched along with Leukemia L 1210 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Forsch, R; Rosowsky, A | 1 |
| Forsch, R; Freisheim, JH; Kumar, AA; Rosowsky, A; Uren, J; Wick, M | 1 |
| Lehninger, AL; Moreadith, RW | 1 |
| Barker, AJ; Boyle, FT; Calvert, AH; Hughes, LR; Jackman, AL; Kimbell, R; Marsham, PR; O'Connor, BM; Pegg, SJ; Wardleworth, JM | 1 |
| Bavetsias, V; Bisset, GM; Calvert, AH; Hughes, LR; Jackman, AL; Pawelczak, K; Thornton, TJ | 1 |
| Assaraf, YG; Goldman, ID; Zhao, R | 1 |
| Gao, F; Goldman, ID; Wang, PJ; Zhao, R | 1 |
| Bannai, S; Hishinuma, I; Ishii, T; Watanabe, H | 1 |
| Bader, H; Freisheim, JH; Moran, RG; Radike-Smith, M; Rosowsky, A; Solan, VC; Wright, JE | 1 |
| Bader, H; Freisheim, JH; Kohler, W; Moran, RG; Rosowsky, A | 1 |
10 other study(ies) available for glutamic acid and Leukemia L 1210
| Article | Year |
|---|---|
Methotrexate analogues. 16. Importance of the side-chain amide carbonyl group as a structural determinant of biological activity.
Topics: Animals; Binding, Competitive; Cell Survival; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Lacticaseibacillus casei; Leukemia L1210; Methotrexate; Mice; Structure-Activity Relationship | 1982 |
Methotrexate analogues. 20. Replacement of glutamate by longer-chain amino diacids: effects on dihydrofolate reductase inhibition, cytotoxicity, and in vivo antitumor activity.
Topics: Animals; Antineoplastic Agents; Folic Acid Antagonists; Glutamates; Glutamic Acid; Lacticaseibacillus casei; Leukemia L1210; Methotrexate; Mice | 1983 |
The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.
Topics: Animals; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glutamic Acid; Glutamine; Kidney; Kinetics; Leukemia L1210; Liver Neoplasms, Experimental; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mitochondria; Mitochondria, Liver; NAD; NADP; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymoma; Thymus Neoplasms | 1984 |
Quinazoline antifolate thymidylate synthase inhibitors: replacement of glutamic acid in the C2-methyl series.
Topics: Animals; Antineoplastic Agents; Folic Acid; Folic Acid Antagonists; Glutamic Acid; Leukemia L1210; Mice; Quinazolines; Structure-Activity Relationship; Thymidylate Synthase; Tumor Cells, Cultured | 1995 |
The synthesis and thymidylate synthase inhibitory activity of L-gamma-L-linked dipeptide and L-gamma-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
Topics: 2-Aminoadipic Acid; Animals; Binding Sites; Cell Division; Dipeptides; Drug Stability; Folic Acid; Glutamic Acid; Hydrolases; Hydrolysis; Leukemia L1210; Mice; Structure-Activity Relationship; Thymidylate Synthase | 1994 |
A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.
Topics: Amino Acid Substitution; Animals; Anions; Binding Sites; Biological Transport, Active; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Glutamic Acid; Kinetics; Leukemia L1210; Lysine; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Mutagenesis, Site-Directed; Protein Structure, Secondary; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Role of the amino acid 45 residue in reduced folate carrier function and ion-dependent transport as characterized by site-directed mutagenesis.
Topics: Amino Acid Substitution; Animals; Anions; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Folic Acid; Glutamic Acid; Leucovorin; Leukemia L1210; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Mutagenesis, Site-Directed; Reduced Folate Carrier Protein; Tetrahydrofolates; Transfection; Tumor Cells, Cultured | 2000 |
Mouse lymphoma L1210 cells acquire a new cystine transport activity upon adaptation in vitro.
Topics: Amino Acids; Animals; Biological Transport; Cells, Cultured; Culture Media; Cystine; Ethylmaleimide; Glutamates; Glutamic Acid; Leukemia L1210; Mercaptoethanol; Mice; Sodium; Sulfhydryl Compounds | 1986 |
Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
Topics: Aminobutyrates; Aminopterin; Animals; beta-Alanine; Cell Division; Folic Acid Antagonists; Glutamates; Glutamic Acid; Kinetics; Leukemia L1210; Methotrexate; Mice; Molecular Weight; Ornithine; Peptide Synthases | 1986 |
Methotrexate analogues. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acids.
Topics: Amino Acids, Dicarboxylic; Aminopterin; Animals; Cell Division; Chemical Phenomena; Chemistry; Drug Resistance; Folic Acid Antagonists; Glutamates; Glutamic Acid; Humans; Leukemia L1210; Liver; Methotrexate; Mice; Peptide Synthases; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |