Compounds > glutamic acid

glutamic acid and Ischemia

glutamic acid has been researched along with Ischemia in 146 studies

Research

Studies (146)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.37)18.7374
1990's45 (30.82)18.2507
2000's59 (40.41)29.6817
2010's25 (17.12)24.3611
2020's15 (10.27)2.80

Authors

AuthorsStudies
Andrew, RD; Ayata, C; Brennan, KC; Dawson-Scully, KD; Dreier, JP; Farkas, E; Hartings, JA; Herreras, O; Kirov, SA; Müller, M; Ollen-Bittle, N; Reiffurth, C; Revah, O; Robertson, RM; Ullah, G1
Azami Tameh, A; Karimian, M; Khassafi, N; Vahidinia, Z; Zahraei, Z1
Chen, Y; Du, J; Hou, ST; Li, X; Lu, S; Wang, Y; Yuan, C1
Sharma, DJ; Sultana, J1
Cui, M; Li, K; Lu, M; Wang, X; Zheng, Y1
Coppi, E; Gibb, AJ1
Li, ZQ; Liu, BH; Pu, J; Zhang, XR1
Abdallah, DM; Mohammed, RA; Nassar, NN; Safar, MM; Zaki, OS1
Chu, A; Featherstone, DE; Heit, BS; Larson, J; Park, TJ; Sane, A1
Blixt, J; Gunnarson, E; Song, Y; Wanecek, M1
Andrade, GB; Butt, AM; Costa, SL; da Silva, VDA; de Almeida, MMA; de Assis, AM; de Fátima Dias Costa, M; de Lima Ferreira, BC; de Souza, SB; Ferdandez, LG; Ferreira, RS; Hoppe, JB; Longoni, A; Moreira, JCF; Pieropan, F; Ribeiro, PR; Rivera, AD; Salbego, CG; Silva, JHCE1
Almeida, RD; Neves, D; Salazar, IL; Silva, RM1
Bona, M; Bonova, P; Gottlieb, M; Končekova, J; Kotorova, K1
Fushimi, M; Kawase, H; Mizoue, R; Morimatsu, H; Murai, S; Sato, S; Takeda, Y1
Bayer, KU; Buonarati, OR; Chalmers, NE; Cook, SG; Coultrap, SJ; Goodell, DJ; Herson, PS; Quillinan, N; Restrepo, S; Rumian, NL; Tullis, JE1
Egger, V; Frommherz, I; Grosche, A; Haydon, PG; Hirrlinger, J; Illes, P; Jägle, H; Pannicke, T; Pfrieger, FW; Rupprecht, V; Volz, C; Wagner, L1
Bond, P; Doyle, S; Fern, R; Hansen, DB; Harper, G; Valentino, M; Vella, J; Zammit, C1
Adam, AP; Ashkavand, Z; Bach, MD; Martino, N; Mongin, AA; Norman, KR; Wilson, CS1
Bona, M; Bonova, P; Gottlieb, M; Jachova, J; Macakova, L; Nemethova, M1
Gu, S; Li, M; Ma, T; Sun, XJ; Wang, Y; Wang, YG; Zhou, L1
Adornetto, A; Bagetta, G; Bonanno, G; Cavaliere, F; Corasaniti, MT; Milanese, M; Morrone, LA; Nucci, C; Russo, R; Varano, GP1
Craig, AJ; Hopkins, RM; Knuckey, NW; Meloni, BP; Milech, N; Watt, PM1
Casini, G; Catalani, E; Cervia, D; D'Alessandro, A; Gevi, F; Zolla, L1
Barnstable, CJ; Huang, P; Li, W; Lu, J; Yang, C; Zhang, C; Zhang, SS1
Ganev, EG; Hiruma-Lima, CA; Martins, DF; Mazzardo-Martins, L; Nishijima, CM; Rocha, LR; Santos, AR1
Ambrósio, AF; Coreixas, VS; Domith, I; Loiola, EC; Martins, T; Oliveira, NA; Paes-de-Carvalho, R; Portugal, CC; Relvas, JB; Santiago, AR; Socodato, R1
Acosta, ML; Guo, CX; Kalloniatis, M; Nivison-Smith, L; O'Brien, BJ; Truong, M1
Abbruscato, TJ; Islam, MR; Karamyan, VT; Yang, L1
Shoji, A; Sugawara, M; Tanaka, K1
Ding, X; Dong, X; Song, C; Wu, X; Zheng, L1
Chen, J; Cheng, Z; Guo, L; He, Z; Huang, L; Li, H; Li, Q1
Bouitbir, J; Chakfe, N; Di Marco, P; Geny, B; Kretz, JG; Piquard, F; Ribera, F; Thaveau, F; Zoll, J1
Batista, MC; Cordeiro, Mdo N; da Silva, AJ; de Castro Junior, CJ; Gomez, MV; Guatimosim, C; Kushmerick, C; Massensini, AR; Pinheiro, AC; Prado, MA; Richardson, M; Romano-Silva, MA1
Ma, N; Sasoh, M; Uji, Y1
Barabás, P; Dobolyi, A; Héja, L; Kardos, J; Kékesi, KA; Lasztóczi, B; Madsen, K; Nyitrai, G; Palkovits, M; Schousboe, A; Tárkányi, G; Toke, O1
Chae, SJ; Choi, S; Choi, SK; Kang, SW; Lee, GJ; Pak, YK; Park, E; Park, HK1
Kostandy, BB1
Du, G; He, X; Qin, H; Wang, Y1
Hara, A; Matsubara, A; Namba, A; Sasaki, A; Shinkawa, H; Tabuchi, K; Yamamoto, Y1
Aylsworth, A; Brunette, E; Hewitt, M; Mealing, GA; Tauskela, JS1
Borgens, RB; Liu-Snyder, P1
Chen, X; Liu, Y; Sun, Q; Tang, R; Wang, W; Wu, X; Xie, M; Yu, Z1
Chai, S; Ellisman, MH; Ju, WK; Kim, KY; Lee, D; Lindsey, JD; Noh, YH; Weinreb, RN1
Bibby, BM; Jespersen, B; Jørgensen, TM; Keller, AK; Kjerkegaard, UK; Krag, SR; Stolle, LB; Vittrup, DM1
Acosta, ML; de Souza, CF; Kalloniatis, M; McGhee, CN; Polkinghorne, PJ1
Bert, L; Robert, F; Stoppini, L1
Röhrborn, HJ; Scheufler, KM; Zentner, J1
Furue, H; Kumamoto, E; Matsumoto, N; Yoshimura, M1
Trotti, D1
Deng, J; Gao, R; Wu, DZ1
Nau, R1
Bui, BV; Kalloniatis, M; Vingrys, AJ1
Bertsch, T; Denz, C; Ellinger, K; Henn, C; Janke, C; Klein, J; Korth, U; Krieter, H1
Anagnostopoulos, PV; Filis, KA; Katsamouris, A; Pipinos, II; Sabbah, HN; Sharov, VG; Shepard, AD; Todor, A1
King, N; Lin, H; McGivan, JD; Suleiman, MS1
Bonne, C; D'Aldin, C; Maurin, L; Muller, A; Payet, O1
Dikranian, K; Olney, JW; Tenkova, T; Young, C1
Kauppinen, TM; Swanson, RA; Ying, W1
Büyükuysal, RL1
Barnett, NL; Bull, ND1
Bringmann, A; Klaus, C; Reichenbach, A; Rillich, K; Syková, E; Uckermann, O; Ulbricht, E; Vargová, L; Weick, M; Wiedemann, P1
Ballanyi, K; Klapproth, N; Kulik, A; Metzger, F; Sendtner, M1
Long, JB; Meyerhoff, JL; Robinson, MB; Slusher, BS; Yourick, DL1
Lu, YF; Matsui, H; Matsushita, M; Tomizawa, K; Wu, HY; Yan, Z; Yuen, EY1
Gao, CJ; Li, WX; Lin, MT; Niu, KC; Tsai, HM1
Hara, H; Morimoto, N; Nagai, H; Shimazawa, M; Yamashima, T1
Andrade, AL; Attwell, D; Hamann, M; Mohr, C; Rossi, DJ1
Hirano, A; Nakamura, N; Negishi, K; Sugawara, M1
Cia, D; Dreyfus, H; Fuchs, C; Picaud, S; Sahel, JA; Tessier, LH; Vallazza-Deschamps, G1
Attwell, D; Bergersen, LH; Cavelier, P; Káradóttir, R1
Beck-Sickinger, AG; Bringmann, A; Kalisch, F; Kutzera, F; Reichenbach, A; Uckermann, O; Wiedemann, P; Wolf, A1
Di Luca, M; Gardoni, F1
Bicker, G; Gierse, A; Paquet-Durand, F1
Assmann, G; Berger, K; Cheng, S; Funke, H; Huge, A; John, U; Kessler, C; Ringelstein, EB; Stögbauer, F; Stoll, M; Wellmann, J1
Barnett, NL; Bull, ND; Takamoto, K1
Cao, J; Coffey, ET; Courtney, MJ; Forsberg, KM; Koistinaho, M; Komarovski, V; Mäki-Hokkonen, AM; Semenova, MM1
Chen, M; Gu, JG; Tao, YX1
Fagioni, M; Grandinetti, F; Timperio, AM; Zolla, L1
Arthur, PG; Bojarski, C; Boulos, S; Knuckey, NW; Meloni, BP1
Bagetta, G; Cavaliere, F; Cerulli, A; Corasaniti, MT; Mancino, R; Morrone, LA; Nucci, C; Rombolà, L; Spanò, A; Tartaglione, R1
Baranyi, M; Illes, P; Sperlágh, B; Vizi, ES; Zsilla, G1
Bagnoli, P; Casini, G; Cervia, D1
Cunarro, JA; Johnson, WA; Schultz, SE; Weiner, MW1
Herrera, AJ; Osborne, NN1
Choi, DW; Cronin, CS; Helfrich, LR; Kouchoukos, NT; Lobner, DC; Nitta, T; Rokkas, CK1
Ichihara, K; Nakai, T; Satoh, K1
Calinon, F; Delbarre, B; Delbarre, G1
Backhauss, C; Krieglstein, J; Peruche, B; Prehn, JH1
Allen, BT; Davis, CG; Karl, I; Osborne, D1
Ball, SG; O'Neill, CM; Vaughan, PF1
Choi, DW; Helfrich, LR; Kouchoukos, NT; Lobner, DC; Rokkas, CK1
Eybalin, M; Gervais d'Aldin, C; Puel, JL; Pujol, R1
Ho, XP; Lu, BF; Lu, YM; Yan, YL; Zhao, FQ1
Jung, JS; Kim, BS; Kim, YH; Kim, YK; Lee, SH; Woo, JS1
Chang, CJ; Lam, TT; McCole, SM; Perlman, JI; Pulluru, P; Tso, MO1
Acosta, GB; Wikinski, SI1
Malmberg, AB; Marsala, M; Yaksh, TL1
Cornell-Bell, A; Kim, WT; Madden, KS1
Larsen, AK; Osborne, NN1
Ball, R; Durkin, JP; Stanimirovic, DB1
Chamuleau, RA; Daalhuisen, J; Maas, MA; Quack, G; Vogels, BA1
Aeba, R; Ito, T; Kawada, S; Koto, A; Mitsumaru, A; Mori, A; Nakamichi, T; Odaguchi, H; Ueda, T; Yasudo, M; Yozu, R1
Bonne, C; Muller, A; Villain, M1
Ungerstedt, U1
Kawada, S; Nakamichi, T1
Oliveira, C; Pereira, C; Santos, MS1
Katayama, K; Kimura, M; Kuwada, M; Miyagawa, T; Nishizawa, Y; Sawada, K1
Defraigne, JO; Limet, R1
Bach, M; Feuerstein, TJ; Knörle, R; Lagrèze, WA1
Nakamichi, T1
Adachi, K; Akaike, A; Honda, Y; Kaneda, K; Kashii, S; Kume, T; Masai, H; Morizane, C; Ueda, M1
Matsumoto, M; Nakakimura, K; Sakabe, T; Wakamatsu, H1
Baranyi, M; Milusheva, E; Nakai, T; Satoh, T; Uchihashi, Y; Vizi, ES1
Haruta, A; Komune, S; Matsubara, A; Matsuda, K; Tono, T; Usami, S1
Haruta, A; Kawabata, Y; Matsubara, A; Matsuda, K; Shinkawa, H; Takumi, Y; Tono, T; Usami, S1
Ishiguro, S; Kobayashi, N; Nishikawa, S; Tamai, M; Tomita, H1
Eppinger, M; Lemmon, G; Miller, S; Nolan, D; Peoples, J; Prem, JT1
Kawazura, H; Matsuoka, T; Morikawa, M; Morikawa, O; Nishizaki, T; Saito, N; Shiga, Y; Shimada, F1
Kvrivishvili, GI; Mitagvariia, NP1
Cousins, MJ; Edwards, SR; Lin, Y; Mather, LE; Power, I1
Huster, D; Reichelt, W; Reichenbach, A1
Tobinaga, S1
Agostinho, P; Cunha, RA; Melo, J; Oliveira, CR; Rego, AC1
Blauth, E; Feuerstein, TJ; Jehle, T; Knörle, R; Lagrèze, WA; Lücking, CH; Schnierle, P1
Donello, JE; Gil, DW; Padillo, EU; Webster, ML; Wheeler, LA1
Drago, F; Emmi, I; Marino, A; Marino, V; Scalia, CC; Valzelli, S1
Fukumori, R; Goshima, Y; Hagiwara, Y; Kubo, T; Misu, Y; Yokoi, T1
Danbolt, NC1
Jackson, PF; Slusher, BS1
Sarthy, VP1
Kawakami, M; Kozaki, S; Sato, K; Sekiguchi, M; Takahashi, M1
Kuriyama, H; Nakagawa, M; Tsuda, M1
Amemiya, H; Enosawa, S; Fujita, Y; Hiramatsu, S; Matsumura, T; Miyashita, T; Omasa, T; Suga, K; Suzuki, S1
Barnett, NL; Bull, ND; Pow, DV1
Hicks, D; Lambrou, GN; Luo, X; Sahel, JA1
Patzke, H; Tsai, LH1
Dejong, CH; Deutz, NE; Kampman, MT; Soeters, PB1
Bradford, HF; Coutinho-Netto, J; Dias, JJ; Lachat, JJ; Louzada-Júnior, P; Santos, WF1
Code, WE; Hertz, L; Huang, R; Juurlink, BH; Peng, L; Sochocka, E; Yu, AC; Zhong, Z1
Kalloniatis, M; Robin, LN1
Badía, A; López-Farré, A; López-Novoa, JM; Montañés, I; Rengel, MA1
Bosman, DK; Bovée, WM; Chamuleau, RA; De Graaf, AA; Deutz, NE; Jörning, GG; Maas, MA; Van Eijk, HM; vd Hulst, RW1
Bovée, WM; de Graaf, AA1
Goodman, JC; Robertson, CS; Simpson, RK1
Eybalin, M; Lenoir, M; Puel, JL; Pujol, R; Rebillard, G; Recasens, M1
Bengtsson, F; Grampp, W; Siesjö, BK; Theander, S1

Reviews

13 review(s) available for glutamic acid and Ischemia

ArticleYear
Molecular mechanisms of ischemia and glutamate excitotoxicity.
    Life sciences, 2023, Sep-01, Volume: 328

    Topics: Animals; Cell Death; Glutamic Acid; Humans; Ischemia; Mammals; Receptors, Glutamate; Stroke

2023
The role of glutamate in neuronal ischemic injury: the role of spark in fire.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:2

    Topics: Animals; Brain Injuries; Cell Death; Glutamic Acid; Humans; Ischemia; Neurons; Reactive Oxygen Species; Receptors, Glutamate

2012
Understanding secondary injury.
    The Quarterly review of biology, 2012, Volume: 87, Issue:2

    Topics: Apoptosis; Brain Injuries; Calcium Channels; Cell Death; Edema; Glutamic Acid; Hemorrhage; Humans; Ischemia; Lipid Peroxidation; Neurons; Reperfusion Injury; Sodium Channels; Spinal Cord Injuries; Stroke; Trauma, Nervous System; Wounds and Injuries; Zinc

2012
A role for glutamate transporters in neurodegenerative diseases.
    Advances in experimental medicine and biology, 2002, Volume: 513

    Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Glutamic Acid; Humans; Ischemia; Mercury; Neurodegenerative Diseases; Synaptic Transmission

2002
Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia.
    Current molecular medicine, 2004, Volume: 4, Issue:2

    Topics: Animals; Animals, Newborn; Apoptosis; Brain; Cell Death; Central Nervous System; Glutamic Acid; Hypoxia; Hypoxia-Ischemia, Brain; Immunohistochemistry; Ischemia; Microscopy, Electron; Nerve Degeneration; Neurons; Rats; Silver Staining; Synapses; Time Factors

2004
Astrocyte influences on ischemic neuronal death.
    Current molecular medicine, 2004, Volume: 4, Issue:2

    Topics: Animals; Astrocytes; Brain; Cell Death; Cytokines; Edema; Gap Junctions; Glutamic Acid; Humans; Ischemia; Models, Biological; Neovascularization, Pathologic; Neurons; Oxidants; Oxygen; Potassium; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2004
New targets for pharmacological intervention in the glutamatergic synapse.
    European journal of pharmacology, 2006, Sep-01, Volume: 545, Issue:1

    Topics: Alzheimer Disease; Animals; Epilepsy; Glutamic Acid; Humans; Huntington Disease; Ischemia; Parkinson Disease; Protein Kinases; Receptors, N-Methyl-D-Aspartate; Synapses

2006
Physiology and pathology of somatostatin in the mammalian retina: a current view.
    Molecular and cellular endocrinology, 2008, May-14, Volume: 286, Issue:1-2

    Topics: Amacrine Cells; Animals; Diabetic Retinopathy; Glutamic Acid; Humans; Ischemia; Receptors, Somatostatin; Retinal Ganglion Cells; Retinal Neurons; Retinal Vessels; Signal Transduction; Somatostatin

2008
[Role of excitatory amino acids in neuropathology].
    Medicina, 1995, Volume: 55, Issue:4

    Topics: Animals; Epilepsy; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ischemia; Neuroglia; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia

1995
[Current concepts of involvement of glutamate in ischemic damage of the brain tissue].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 1999, Volume: 85, Issue:12

    Topics: Animals; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ischemia; Receptors, N-Methyl-D-Aspartate

1999
Glutamate uptake.
    Progress in neurobiology, 2001, Volume: 65, Issue:1

    Topics: Amino Acid Transport System X-AG; Anesthetics; Animals; ATP-Binding Cassette Transporters; Bone and Bones; Brain; Carrier Proteins; Ethanol; Extracellular Space; Female; Gene Expression Regulation; Glutamic Acid; Glutamine; Hepatic Encephalopathy; HIV Infections; Humans; Intracellular Fluid; Ion Channel Gating; Ion Channels; Ion Transport; Ischemia; Male; Mammals; Mercury Poisoning; Monocarboxylic Acid Transporters; Nerve Tissue Proteins; Nervous System Diseases; Neuroglia; Neurons; Neurotransmitter Agents; Organ Specificity; Placenta; Potassium; Pregnancy; Protein Conformation; Rats; Receptors, Glutamate; Sodium; Synapses; Synaptic Transmission; Viscera

2001
Interrelationship between retinal ischaemic damage and turnover and metabolism of putative amino acid neurotransmitters, glutamate and GABA.
    Documenta ophthalmologica. Advances in ophthalmology, 1992, Volume: 80, Issue:4

    Topics: Amino Acids; Animals; Biological Transport; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ischemia; Macaca; Neurotransmitter Agents; Oxygen Consumption; Retina; Retinal Vessels

1992
Calcium, excitotoxins, and neuronal death in the brain.
    Annals of the New York Academy of Sciences, 1989, Volume: 568

    Topics: Animals; Brain; Calcium; Calcium Channels; Cell Survival; Depression; Glutamates; Glutamic Acid; Homeostasis; Humans; Hypoglycemia; Hypoxia; Ischemia; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1989

Other Studies

133 other study(ies) available for glutamic acid and Ischemia

ArticleYear
Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization.
    Neurocritical care, 2022, Volume: 37, Issue:Suppl 1

    Topics: Brain; Brain Injuries; Brain Ischemia; Cortical Spreading Depression; Glutamic Acid; Humans; Ischemia

2022
Calcitriol Pretreatment Attenuates Glutamate Neurotoxicity by Regulating NMDAR and CYP46A1 Gene Expression in Rats Subjected to Transient Middle Cerebral Artery Occlusion.
    Journal of neuropathology and experimental neurology, 2022, 03-29, Volume: 81, Issue:4

    Topics: Animals; Brain Ischemia; Calcitriol; Cholesterol 24-Hydroxylase; Disease Models, Animal; Gene Expression; Glutamic Acid; Infarction, Middle Cerebral Artery; Ischemia; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Stroke

2022
PKCα phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice.
    Signal transduction and targeted therapy, 2022, 03-23, Volume: 7, Issue:1

    Topics: Animals; Brain Ischemia; Excitatory Amino Acid Transporter 2; Glutamic Acid; Ischemia; Mice; Phosphorylation; Protein Kinase C-alpha

2022
Evaluation of Serum Ferritin as a Prognostic Marker in Acute Ischemic Stroke Patients-A Prospective Cohort Study.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Brain Ischemia; Cross-Sectional Studies; Ferritins; Glutamic Acid; Humans; Ischemia; Ischemic Stroke; Prognosis; Prospective Studies; Severity of Illness Index; Stroke; Treatment Outcome

2022
The regulatory role of NAAG-mGluR3 signaling on cortical synaptic plasticity after hypoxic ischemia.
    Cell communication and signaling : CCS, 2022, 04-20, Volume: 20, Issue:1

    Topics: Animals; Cerebral Cortex; Dipeptides; Glutamic Acid; Ischemia; Male; Neuronal Plasticity; Neurotransmitter Agents; Receptors, Metabotropic Glutamate; Swine

2022
Selective block of adenosine A
    British journal of pharmacology, 2022, Volume: 179, Issue:20

    Topics: Adenosine; Animals; Glucose; Glutamic Acid; Ion Channels; Ischemia; Ligands; Neurons; Oxygen; Rats; Rats, Wistar; Receptor, Adenosine A2A; Tetrodotoxin

2022
The effects of hypothermia on glutamate and γ-aminobutyric acid metabolism during ischemia in monkeys: a repeated-measures ANOVA study.
    Scientific reports, 2022, 08-25, Volume: 12, Issue:1

    Topics: Amino Acids; Analysis of Variance; Animals; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid; Hypothermia; Ischemia; Ischemic Stroke; Neurotransmitter Agents

2022
Cilostazol Alleviates NLRP3 Inflammasome-Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories.
    Molecular neurobiology, 2022, Volume: 59, Issue:12

    Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cerebral Cortex; Cilostazol; Dopamine; Glutamic Acid; Hyperalgesia; Inflammasomes; Ischemia; Mice; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley

2022
Tonic extracellular glutamate and ischaemia: glutamate antiporter system x
    The Journal of physiology, 2023, Volume: 601, Issue:3

    Topics: Animals; Antiporters; Brain Ischemia; Glutamic Acid; Hippocampus; Hypoxia; Ischemia; Mice; Mice, Transgenic; Oxygen; Stroke

2023
EPO has multiple positive effects on astrocytes in an experimental model of ischemia.
    Brain research, 2023, Mar-01, Volume: 1802

    Topics: Astrocytes; Brain Injuries, Traumatic; Erythropoietin; Glutamic Acid; Humans; Ischemia; Ischemic Stroke; Models, Theoretical; NAD; Sodium-Potassium-Exchanging ATPase

2023
Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia.
    BMC complementary medicine and therapies, 2023, May-11, Volume: 23, Issue:1

    Topics: Animals; Astrocytes; Glutamic Acid; Hippocampus; Homeostasis; Ischemia; Methylene Chloride; Mice; Mice, Transgenic; Oligodendroglia; Oxygen; Plant Extracts; Rats; Rats, Wistar; Seeds

2023
Remote Ischaemic Preconditioning Accelerates Brain to Blood Glutamate Efflux via EAATs-mediated Transport.
    Neurochemical research, 2023, Volume: 48, Issue:12

    Topics: Animals; Brain; Glutamic Acid; Glutathione; Humans; Ischemia; Ischemic Preconditioning

2023
Extracellular Glutamate Concentration Increases Linearly in Proportion to Decreases in Residual Cerebral Blood Flow After the Loss of Membrane Potential in a Rat Model of Ischemia.
    Journal of neurosurgical anesthesiology, 2021, Oct-01, Volume: 33, Issue:4

    Topics: Animals; Cerebrovascular Circulation; Glutamic Acid; Ischemia; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley

2021
CaMKII versus DAPK1 Binding to GluN2B in Ischemic Neuronal Cell Death after Resuscitation from Cardiac Arrest.
    Cell reports, 2020, 01-07, Volume: 30, Issue:1

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Death-Associated Protein Kinases; Dendritic Spines; Female; Glutamic Acid; Heart Arrest; HEK293 Cells; Humans; Ischemia; Male; Mice; Mice, Inbred C57BL; Mutation; Neuroprotection; Neuroprotective Agents; Neurotoxins; Protein Binding; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Resuscitation

2020
Suppression of SNARE-dependent exocytosis in retinal glial cells and its effect on ischemia-induced neurodegeneration.
    Glia, 2017, Volume: 65, Issue:7

    Topics: Animals; Calcium-Binding Proteins; Disease Models, Animal; Doxycycline; Ependymoglial Cells; Exocytosis; Glial Fibrillary Acidic Protein; Glutamic Acid; Intermediate Filaments; Ischemia; Light; Mice; Mice, Transgenic; Microfilament Proteins; Nerve Degeneration; Protein Kinase C-alpha; Receptors, Purinergic P2Y1; Retina; Retinal Ganglion Cells; SNARE Proteins; Vascular Endothelial Growth Factor A

2017
Vesicular glutamate release from central axons contributes to myelin damage.
    Nature communications, 2018, 03-12, Volume: 9, Issue:1

    Topics: Animals; Axons; Cytoplasmic Vesicles; Female; Glutamic Acid; Humans; Ischemia; Male; Mice; Mice, Inbred C57BL; Myelin Sheath; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2018
Metabolic constraints of swelling-activated glutamate release in astrocytes and their implication for ischemic tissue damage.
    Journal of neurochemistry, 2019, Volume: 151, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glucose; Glutamic Acid; Ischemia; Male; Rats; Rats, Sprague-Dawley

2019
Neuroprotection mediated by remote preconditioning is associated with a decrease in systemic oxidative stress and changes in brain and blood glutamate concentration.
    Neurochemistry international, 2019, Volume: 129

    Topics: Animals; Brain; Glutamic Acid; Ischemia; Ischemic Preconditioning; Male; Neuroprotection; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase

2019
Penehyclidine hydrochloride protects against oxygen and glucose deprivation injury by modulating amino acid neurotransmitters release.
    Neurological research, 2013, Volume: 35, Issue:10

    Topics: Amino Acids; Animals; Glucose; Glutamic Acid; Hippocampus; Ischemia; Male; Neurons; Oxygen; Quinuclidines; Rats; Rats, Sprague-Dawley

2013
Impairment of neuronal glutamate uptake and modulation of the glutamate transporter GLT-1 induced by retinal ischemia.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Animals; Aspartic Acid; Biological Transport; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Intraocular Pressure; Ischemia; Male; Neurons; Rats; Rats, Wistar; Retina; Synaptosomes

2013
The neuroprotective efficacy of cell-penetrating peptides TAT, penetratin, Arg-9, and Pep-1 in glutamic acid, kainic acid, and in vitro ischemia injury models using primary cortical neuronal cultures.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:2

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Survival; Cell-Penetrating Peptides; Cells, Cultured; Cerebral Cortex; Cysteamine; Gene Products, tat; Glutamic Acid; Inhibitory Concentration 50; Ischemia; Kainic Acid; Models, Biological; Molecular Sequence Data; Neurons; Neuroprotective Agents; Neurotoxins; Oligopeptides; Peptides; Rats; Rats, Sprague-Dawley

2014
Protective effects of the neuropeptides PACAP, substance P and the somatostatin analogue octreotide in retinal ischemia: a metabolomic analysis.
    Molecular bioSystems, 2014, Volume: 10, Issue:6

    Topics: Animals; Cell Death; Female; Gene Expression Regulation; Glutamic Acid; Ischemia; Male; Metabolomics; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Octreotide; Pituitary Adenylate Cyclase-Activating Polypeptide; Retina; Substance P; Vascular Endothelial Growth Factor A

2014
Tetrandrine protects mouse retinal ganglion cells from ischemic injury.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Animals; Benzylisoquinolines; Caspase 3; Cell Line; Cell Survival; Ciliary Neurotrophic Factor; Cytoprotection; Glutamic Acid; Humans; Ischemia; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Oxidative Stress; Rats; Retinal Ganglion Cells

2014
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
    European journal of pharmacology, 2014, Aug-05, Volume: 736

    Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Hyperalgesia; Ischemia; Ketanserin; Male; Mice; Monoterpenes; Neuralgia; Pain, Postoperative; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2014
c-Src function is necessary and sufficient for triggering microglial cell activation.
    Glia, 2015, Volume: 63, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Cells, Cultured; Chickens; CSK Tyrosine-Protein Kinase; Gliosis; Glutamic Acid; HEK293 Cells; Humans; Inflammation; Ischemia; Lipopolysaccharides; Male; Mice; Microglia; Neurons; Phagocytosis; Proto-Oncogene Proteins pp60(c-src); Rats, Wistar; Reperfusion Injury; Retinal Neurons; src-Family Kinases; Tumor Necrosis Factor-alpha

2015
Vinpocetine modulates metabolic activity and function during retinal ischemia.
    American journal of physiology. Cell physiology, 2015, May-01, Volume: 308, Issue:9

    Topics: Animals; Cell Death; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Energy Metabolism; Ependymoglial Cells; Evoked Potentials; Glucose; Glutamic Acid; Ischemia; L-Lactate Dehydrogenase; Neuroprotective Agents; Rats, Sprague-Dawley; Retinal Diseases; Tissue Culture Techniques; Vinca Alkaloids

2015
In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment.
    Brain research, 2015, Jun-03, Volume: 1609

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Brain Edema; Brain Infarction; Brain Ischemia; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glutamic Acid; Ischemia; Motor Activity; Neurons; Neuroprotective Agents; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reperfusion Injury; Severity of Illness Index; Stroke

2015
An enzyme-entrapped agarose gel for visualization of ischemia-induced L-glutamate fluxes in hippocampal slices in a flow system.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2015, Volume: 31, Issue:4

    Topics: Amino Acid Oxidoreductases; Enzymes, Immobilized; Gels; Glutamic Acid; Hippocampus; Horseradish Peroxidase; Ischemia; L-Lactate Dehydrogenase; Molecular Imaging; Sepharose

2015
Effects of Chronic Alcohol Exposure on the Modulation of Ischemia-Induced Glutamate Release via Cannabinoid Receptors in the Dorsal Hippocampus.
    Alcoholism, clinical and experimental research, 2015, Volume: 39, Issue:10

    Topics: Animals; Arachidonic Acids; Cannabinoids; Dose-Response Relationship, Drug; Ethanol; Glutamic Acid; Hippocampus; Indoles; Infarction, Middle Cerebral Artery; Ischemia; Male; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant

2015
Inhibition of intracellular Ca2+ release by a Rho-kinase inhibitor for the treatment of ischemic damage in primary cultured rat hippocampal neurons.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; Intracellular Space; Ischemia; Neurons; Potassium Chloride; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; rho-Associated Kinases

2009
Contralateral leg as a control during skeletal muscle ischemia-reperfusion.
    The Journal of surgical research, 2009, Volume: 155, Issue:1

    Topics: Animals; Ascorbic Acid; Cell Respiration; Electron Transport Chain Complex Proteins; Glutamic Acid; Ischemia; Lower Extremity; Malates; Male; Mitochondria, Muscle; Mitochondrial Diseases; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury; Succinic Acid; Tetramethylphenylenediamine

2009
Phoneutria spider toxins block ischemia-induced glutamate release, neuronal death, and loss of neurotransmission in hippocampus.
    Hippocampus, 2009, Volume: 19, Issue:11

    Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cell Death; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; In Vitro Techniques; Ischemia; Neurons; Neuropeptides; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Rats; Rats, Wistar; Spider Venoms; Synaptic Transmission; Time Factors

2009
Preservation of glutamate immunoreactivity and ischemic change in photoreceptor inner segments in the retina after different protocols of perfusion fixation.
    Ophthalmic research, 2009, Volume: 42, Issue:1

    Topics: Animals; Cats; Glutamic Acid; Immunoenzyme Techniques; Ischemia; Reperfusion Injury; Retinal Photoreceptor Cell Inner Segment; Retinal Vessels; Tissue Fixation

2009
Glutamate uptake triggers transporter-mediated GABA release from astrocytes.
    PloS one, 2009, Sep-24, Volume: 4, Issue:9

    Topics: Animals; Astrocytes; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Humans; Ischemia; Mice; Models, Biological; Neurons; Rats

2009
The role of glutamate release on voltage-dependent anion channels (VDAC)-mediated apoptosis in an eleven vessel occlusion model in rats.
    PloS one, 2010, Dec-21, Volume: 5, Issue:12

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Biosensing Techniques; Caspase 3; Glutamic Acid; Ischemia; Laser-Doppler Flowmetry; Male; Microscopy, Atomic Force; Mitochondria; Neurons; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Voltage-Dependent Anion Channels

2010
[Activity evaluation of components and preparation of effective components group of xiaoxuming decoction for anti-cerebral ischemic].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:15

    Topics: Animals; Brain; Cell Survival; Drugs, Chinese Herbal; Free Radical Scavengers; Glutamic Acid; Hydrogen Peroxide; Ischemia; Male; Mitochondria; PC12 Cells; Rats; Rats, Wistar

2011
Immunoelectron microscopic analysis of neurotoxic effect of glutamate in the vestibular end organs during ischemia.
    Acta oto-laryngologica, 2012, Volume: 132, Issue:7

    Topics: Animals; Disease Models, Animal; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Ischemia; Microscopy, Immunoelectron; Presynaptic Terminals; Risk Factors; Time Factors; Vestibule, Labyrinth

2012
Preconditioning induces tolerance by suppressing glutamate release in neuron culture ischemia models.
    Journal of neurochemistry, 2012, Volume: 122, Issue:2

    Topics: Animals; Calcium; Calcium Signaling; Cell Hypoxia; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Ischemia; Ischemic Preconditioning; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, GABA; Receptors, Presynaptic; Sodium; Sodium-Potassium-Exchanging ATPase; Vesicular Glutamate Transport Proteins; Zinc

2012
Involvement of TREK-1 activity in astrocyte function and neuroprotection under simulated ischemia conditions.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Bupivacaine; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Culture Media, Serum-Free; Gene Expression Regulation; Glutamic Acid; Homeostasis; Ischemia; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Potassium Channels, Tandem Pore Domain; Quinine; Rats; S100 Calcium Binding Protein beta Subunit; S100 Proteins

2013
Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; bcl-2-Associated X Protein; bcl-Associated Death Protein; Brimonidine Tartrate; DNA-Binding Proteins; Glutamic Acid; Ischemia; Mitochondrial Proteins; Oxidative Phosphorylation; Oxidative Stress; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Diseases; Retinal Ganglion Cells; Superoxide Dismutase; Transcription Factors

2012
Fast detection of renal ischemia in transplanted kidneys with delayed graft function-an experimental study.
    Transplantation, 2013, Jan-27, Volume: 95, Issue:2

    Topics: Animals; Biomarkers; Catheters; Cold Ischemia; Constriction; Delayed Graft Function; Disease Models, Animal; Diuresis; Early Diagnosis; Glomerular Filtration Rate; Glutamic Acid; Glycerol; Ischemia; Kidney Cortex; Kidney Transplantation; Lipocalins; Microdialysis; Predictive Value of Tests; Renal Artery Obstruction; Swine; Time Factors

2013
Amino acid immunoreactivity in normal human retina and after brachytherapy.
    Clinical & experimental optometry, 2013, Volume: 96, Issue:5

    Topics: Aged; Amino Acids; Brachytherapy; Eye Banks; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Ischemia; Male; Retina; Retinal Diseases; Taurine

2013
Blockade of NMDA-receptors or calcium-channels attenuates the ischaemia-evoked efflux of glutamate and phosphoethanolamine and depression of neuronal activity in rat organotypic hippocampal slice cultures.
    Comptes rendus biologies, 2002, Volume: 325, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium Channel Blockers; Cell Hypoxia; Deoxyglucose; Diltiazem; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Ischemia; Kinetics; Neurons; Organ Culture Techniques; Phosphatidylethanolamines; Potassium Cyanide; Rats; Receptors, N-Methyl-D-Aspartate

2002
Does tissue oxygen-tension reliably reflect cerebral oxygen delivery and consumption?
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Animals; Blood Gas Analysis; Brain; Brain Chemistry; Cerebrovascular Circulation; Electron Transport Complex IV; Electrophysiology; Glutamic Acid; Ischemia; Kinetics; Lactic Acid; Male; Oxidation-Reduction; Oxygen; Oxygen Consumption; Pyruvic Acid; Rabbits; Spectroscopy, Near-Infrared

2002
GABA-mediated inhibition of glutamate release during ischemia in substantia gelatinosa of the adult rat.
    Journal of neurophysiology, 2003, Volume: 89, Issue:1

    Topics: Age Factors; Anesthetics, Local; Animals; Bicuculline; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glycine Agents; Ischemia; Male; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Strychnine; Substantia Gelatinosa; Tetrodotoxin

2003
Detection of glutamate and gamma-aminobutyric acid in vitreous of patients with proliferative diabetic retinopathy.
    Yan ke xue bao = Eye science, 2000, Volume: 16, Issue:3

    Topics: Diabetic Retinopathy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ischemia; Male; Middle Aged; Retinal Neovascularization; Retinal Perforations; Retinal Vessels; Vitreous Body

2000
[Pathophysiology of neuronal injury in bacterial meningitis: concepts and implications].
    Neurologia (Barcelona, Spain), 2003, Volume: 18, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Caspases; Glutamic Acid; Humans; Ischemia; Leukocytes; Meningitis, Bacterial; Neurons; Reactive Oxygen Species

2003
Correlating retinal function and amino acid immunocytochemistry following post-mortem ischemia.
    Experimental eye research, 2003, Volume: 77, Issue:2

    Topics: Animals; Aspartic Acid; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; Ischemia; Rats; Rats, Sprague-Dawley; Retinal Vessels; Time Factors; Vision, Ocular

2003
Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis.
    Resuscitation, 2003, Volume: 58, Issue:2

    Topics: Animals; Brain; Cardiopulmonary Resuscitation; Choline; Extracellular Space; Glucose; Glutamic Acid; Heart Arrest; Intestinal Mucosa; Intestines; Ischemia; Lactic Acid; Microdialysis; Muscle, Skeletal; Peritoneum; Swine; Time Factors

2003
Abnormal mitochondrial respiration in skeletal muscle in patients with peripheral arterial disease.
    Journal of vascular surgery, 2003, Volume: 38, Issue:4

    Topics: Adenosine Diphosphate; Aged; Atractyloside; Biopsy; Enzyme Inhibitors; Female; Glutamic Acid; Humans; In Vitro Techniques; Intermittent Claudication; Ischemia; Malates; Male; Middle Aged; Mitochondria, Muscle; Mitochondrial ADP, ATP Translocases; Muscle, Skeletal; Oxygen Consumption

2003
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Cardiomegaly; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Glutamate Dehydrogenase; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Heart; Heart Rate; Ischemia; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardium; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Sarcolemma; Symporters; Ventricular Pressure

2004
Anti-excitotoxic activity of trimetazidine in the retina.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2004, Volume: 20, Issue:1

    Topics: Administration, Oral; Animals; Cell Line; Disease Models, Animal; Electroretinography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; Rats; Rats, Wistar; Retina; Retinal Diseases; Trimetazidine

2004
Ischemia and reoxygenation induced amino acid release release and tissue damage in the slices of rat corpus striatum.
    Amino acids, 2004, Volume: 27, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Citrulline; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia; Ions; Ischemia; L-Lactate Dehydrogenase; Male; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; Taurine; Tetrodotoxin; Time Factors

2004
Retinal glutamate transporter activity persists under simulated ischemic conditions.
    Journal of neuroscience research, 2004, Nov-15, Volume: 78, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; D-Aspartic Acid; Enzyme Inhibitors; Eye Diseases; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Ischemia; Protein Kinase C; Rats; Retina

2004
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Nov-10, Volume: 24, Issue:45

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cell Size; Circadian Rhythm; Cytochalasin D; Cytoskeleton; Dicarboxylic Acids; Dopamine; Eye Proteins; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; N-Methylaspartate; Neuroglia; Neurons; Nocodazole; Potassium; Pyrrolidines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Xanthenes

2004
Optical assessment of motoneuron function in a "twenty-four-hour" acute spinal cord slice model from fetal rats.
    Journal of neuroscience methods, 2005, Feb-15, Volume: 141, Issue:2

    Topics: Action Potentials; Analysis of Variance; Animals; Calcium; Cell Death; Cell Survival; Cyanides; Diagnostic Imaging; Drug Interactions; Embryo, Mammalian; Fura-2; Glutamic Acid; In Vitro Techniques; Iodoacetates; Ischemia; Mitochondria; Motor Neurons; Propidium; Rats; Rats, Wistar; Rhodamine 123; Spinal Cord; Time Factors

2005
Inhibition of glutamate carboxypeptidase II (NAALADase) protects against dynorphin A-induced ischemic spinal cord injury in rats.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Animals; Anterior Horn Cells; Cell Count; Dose-Response Relationship, Drug; Dynorphins; Glutamate Carboxypeptidase II; Glutamic Acid; Ischemia; Male; Motor Activity; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors

2005
Regulation of N-methyl-D-aspartate receptors by calpain in cortical neurons.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Animals; Blotting, Western; Calcium; Calpain; Down-Regulation; Dynamins; Endocytosis; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Ischemia; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Peptides; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors

2005
Resuscitation from experimental heatstroke by hyperbaric oxygen therapy.
    Critical care medicine, 2005, Volume: 33, Issue:4

    Topics: Animals; Biomarkers; Brain Diseases; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; Hyperbaric Oxygenation; Ischemia; Lactic Acid; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Resuscitation; Survival Analysis; Treatment Outcome; Tumor Necrosis Factor-alpha

2005
Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage.
    Brain research, 2005, May-17, Volume: 1044, Issue:1

    Topics: Animals; Antioxidants; Benzimidazoles; Benzoxazoles; Biphenyl Compounds; Brain Edema; Brain Infarction; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Fluorescent Dyes; Glutamic Acid; Hydrazines; Infarction, Middle Cerebral Artery; Inhibitory Concentration 50; Ischemia; Lipid Peroxidation; Male; Mice; Minocycline; Neurons; Neuroprotective Agents; Oxidative Stress; Picrates; Quinolinium Compounds; Saponins; Tetrazolium Salts; Time Factors

2005
The electrical response of cerebellar Purkinje neurons to simulated ischaemia.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 10

    Topics: Action Potentials; Amino Acid Transport System X-AG; Animals; Calcium; Cerebellum; Excitatory Amino Acid Transporter 2; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia; Ischemia; Mice; Mice, Transgenic; Necrosis; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA

2005
Real-time monitoring of L-glutamate release from mouse brain slices under ischemia with a glass capillary-based enzyme electrode.
    Analytical and bioanalytical chemistry, 2005, Volume: 383, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Biosensing Techniques; Brain; Glass; Glutamic Acid; Ischemia; Male; Mice; Sensitivity and Specificity; Streptomyces; Time Factors

2005
Diltiazem-induced neuroprotection in glutamate excitotoxicity and ischemic insult of retinal neurons.
    Documenta ophthalmologica. Advances in ophthalmology, 2005, Volume: 110, Issue:1

    Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Diltiazem; Glutamic Acid; In Vitro Techniques; Ischemia; Neurons; Neurotoxins; Rats; Rats, Wistar; Retina; Swine

2005
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia.
    Nature, 2005, Dec-22, Volume: 438, Issue:7071

    Topics: Animals; Electric Conductivity; Gene Expression; Glutamic Acid; In Vitro Techniques; Ischemia; Magnesium; Oligodendroglia; Rats; Receptors, N-Methyl-D-Aspartate

2005
Glutamate release by neurons evokes a purinergic inhibitory mechanism of osmotic glial cell swelling in the rat retina: activation by neuropeptide Y.
    Journal of neuroscience research, 2006, Volume: 83, Issue:4

    Topics: Animals; Calcium; Cell Size; Data Interpretation, Statistical; Glutamic Acid; Ischemia; Neuroglia; Neurons; Neuropeptide Y; Rats; Rats, Long-Evans; Receptors, Glutamate; Receptors, Purinergic; Retina; Retinal Vessels; Signal Transduction; Transcriptional Activation

2006
Diltiazem protects human NT-2 neurons against excitotoxic damage in a model of simulated ischemia.
    Brain research, 2006, Dec-08, Volume: 1124, Issue:1

    Topics: Animals; Animals, Newborn; Calcium; Cell Differentiation; Cell Hypoxia; Cell Survival; Cells, Cultured; Diltiazem; Drug Interactions; Glutamic Acid; Humans; Ischemia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Teratocarcinoma; Time Factors

2006
The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies.
    Human genetics, 2007, Volume: 121, Issue:2

    Topics: Aged; Aspartic Acid; Case-Control Studies; Female; Glutamic Acid; Humans; Integrin alpha2; Interleukin-13; Ischemia; Male; Middle Aged; Nitric Oxide Synthase Type III; P-Selectin; Polymorphism, Single Nucleotide; Receptors, CCR2; Receptors, Chemokine; Stroke

2007
Glutamate transport modulation: a possible role in retinal neuroprotection.
    Advances in experimental medicine and biology, 2006, Volume: 572

    Topics: Amino Acid Transport System X-AG; Animals; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electroretinography; Glutamic Acid; Humans; Ischemia; Neuroprotective Agents; Protein Kinase C; Rats; Retina; Retinal Ganglion Cells

2006
Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death.
    Nature neuroscience, 2007, Volume: 10, Issue:4

    Topics: ADP Ribose Transferases; Animals; Animals, Newborn; Botulinum Toxins; Brain; Calcium; cdc42 GTP-Binding Protein; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Functional Laterality; Glutamic Acid; Ischemia; Mice; Mitogen-Activated Protein Kinase 14; Models, Molecular; N-Methylaspartate; Neurons; rhoA GTP-Binding Protein; Transfection

2007
Inward currents induced by ischemia in rat spinal cord dorsal horn neurons.
    Molecular pain, 2007, Apr-25, Volume: 3

    Topics: Age Factors; Animals; Animals, Newborn; Capsaicin; Electric Stimulation; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ischemia; Organ Culture Techniques; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord

2007
Chemically enhanced liquid chromatography/tandem mass spectrometry determination of glutamic acid in the diffusion medium of retinal cells.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:10

    Topics: Animals; Calibration; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Dansyl Compounds; Glutamic Acid; Ischemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Reference Standards; Reproducibility of Results; Retina; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Peroxiredoxin 2 overexpression protects cortical neuronal cultures from ischemic and oxidative injury but not glutamate excitotoxicity, whereas Cu/Zn superoxide dismutase 1 overexpression protects only against oxidative injury.
    Journal of neuroscience research, 2007, Nov-01, Volume: 85, Issue:14

    Topics: Adenoviridae; Analysis of Variance; Animals; Benzene Derivatives; Cell Count; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Ischemia; Ischemic Preconditioning; Neurons; Oxidants; Oxidation-Reduction; Peroxiredoxins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Transduction, Genetic

2007
Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat.
    International review of neurobiology, 2007, Volume: 82

    Topics: Administration, Topical; Animals; Coenzymes; Glutamic Acid; In Situ Nick-End Labeling; Intraocular Pressure; Ischemia; Male; Microdialysis; Rats; Rats, Wistar; Retinal Diseases; Retinal Ganglion Cells; Ubiquinone

2007
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
    Neuroscience, 2007, Oct-12, Volume: 149, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Ischemia; Male; Phenethylamines; Purinergic Agonists; Purinergic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Purinergic; Sodium Channel Blockers; Tetrodotoxin; Triazines; Triazoles; Xanthines

2007
Effects of ischemia on metabolite concentrations in dog renal cortex.
    Renal physiology, 1982, Volume: 5, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Female; Glutamates; Glutamic Acid; Hydroxybutyrates; Ischemia; Keto Acids; Ketoglutaric Acids; Kidney; Kidney Cortex; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats

1982
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
    Neuroscience, 1994, Volume: 59, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin

1994
Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:1

    Topics: Analysis of Variance; Animals; Aspartic Acid; Cardiopulmonary Bypass; Disease Models, Animal; Evoked Potentials, Somatosensory; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypothermia, Induced; Ischemia; Microdialysis; Neurotransmitter Agents; Spinal Cord; Swine; Thoracotomy

1995
Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on mitochondrial respiration in rat liver during ischemia.
    European journal of pharmacology, 1994, Aug-03, Volume: 270, Issue:4

    Topics: Adenosine Diphosphate; Animals; Cell Fractionation; Glutamic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Liver; Lovastatin; Male; Mitochondria, Liver; Oxygen Consumption; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Succinates

1994
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisates; Gerbillinae; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemia; Male; Reperfusion Injury; Retina; Retinal Vessels; Trimetazidine

1994
Protective effects of 5-HT1A receptor agonists against neuronal damage demonstrated in vivo and in vitro.
    Journal of neural transmission. Parkinson's disease and dementia section, 1994, Volume: 8, Issue:1-2

    Topics: Animals; Cell Hypoxia; Cells, Cultured; Chick Embryo; Glutamic Acid; In Vitro Techniques; Ischemia; Male; Neuroprotective Agents; Piperazines; Pyridines; Rats; Receptors, Serotonin; Serotonin Receptor Agonists

1994
Spinal cord ischemia and reperfusion metabolism: the effect of hypothermia.
    Journal of vascular surgery, 1994, Volume: 19, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Body Temperature; Combined Modality Therapy; Energy Metabolism; Glucose; Glutamates; Glutamic Acid; Heparin; Hypothermia, Induced; Intracellular Fluid; Ischemia; Lactates; Lactic Acid; Neurologic Examination; Neurotransmitter Agents; Rabbits; Reperfusion Injury; Sodium Chloride; Spinal Cord

1994
Effects of ischaemic conditions on uptake of glutamate, aspartate, and noradrenaline by cell lines derived from the human nervous system.
    Journal of neurochemistry, 1994, Volume: 63, Issue:2

    Topics: Aspartic Acid; Astrocytoma; Biological Transport; Cell Hypoxia; Cell Line; Glutamates; Glutamic Acid; Humans; Hypoglycemia; Ischemia; Kinetics; Models, Neurological; Neuroblastoma; Norepinephrine; Tritium; Tumor Cells, Cultured

1994
Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia.
    The Annals of thoracic surgery, 1994, Volume: 58, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Dextrorphan; Evoked Potentials; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ischemia; Microdialysis; Motor Cortex; Neurotransmitter Agents; Receptors, Amino Acid; Serine; Spinal Cord; Swine

1994
Pathophysiology of the glutamatergic synapses in the cochlea.
    Acta oto-laryngologica, 1993, Volume: 113, Issue:3

    Topics: Animals; Cochlea; Dendrites; Dopamine; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Ischemia; Piribedil; Quinoxalines; Receptors, Glutamate; Synapses; Vestibulocochlear Nerve

1993
Accumulation of glutamate is regulated by calcium and protein kinase C in rat hippocampal slices exposed to ischemic states.
    Hippocampus, 1993, Volume: 3, Issue:2

    Topics: Alkaloids; Amino Acids; Animals; Benzylisoquinolines; Calcium; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Ischemia; Male; Protein Kinase C; Rats; Synaptosomes

1993
Effect of renal ischaemia on organic compound transport in rabbit kidney proximal tubule.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biological Transport, Active; Cell Membrane; Female; Glomerular Filtration Rate; Glucose; Glutamic Acid; Ischemia; Kidney Tubules, Proximal; Male; Microscopy, Electron; Microvilli; Oxygen Consumption; Rabbits; Sodium-Potassium-Exchanging ATPase; Succinates; Succinic Acid; Tetraethylammonium; Tetraethylammonium Compounds

1995
Disturbances in the distribution of neurotransmitters in the rat retina after ischemia.
    Current eye research, 1996, Volume: 15, Issue:6

    Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Intraocular Pressure; Ischemia; Nerve Degeneration; Neuroglia; Neurotransmitter Agents; Rats; Rats, Inbred Lew; Reperfusion Injury; Retina; Retinal Vessels; Tissue Distribution

1996
The spinal loop dialysis catheter: characterization of use in the unanesthetized rat.
    Journal of neuroscience methods, 1995, Volume: 62, Issue:1-2

    Topics: Alfentanil; Amino Acids; Animals; Arterial Occlusive Diseases; Behavior, Animal; Consciousness; Dinoprostone; Epoxy Compounds; Formaldehyde; Glucose; Glutamic Acid; Heart Arrest; Injections, Spinal; Ischemia; Kainic Acid; Lumbosacral Region; Microdialysis; Pain Measurement; Rats; Spinal Cord Compression; Spine; Time Factors

1995
Glutamate, arachidonic acid, and calcium regulation in cultured hippocampal astrocytes: involvement in ischemia?
    Advances in neurology, 1996, Volume: 71

    Topics: Animals; Arachidonic Acid; Astrocytes; Calcium; Cells, Cultured; Glutamic Acid; Hippocampus; Ischemia; Time Factors

1996
Antigens associated with specific retinal cells are affected by ischaemia caused by raised intraocular pressure: effect of glutamate antagonists.
    Neurochemistry international, 1996, Volume: 29, Issue:3

    Topics: Animals; Antigens; Calbindin 2; Electroretinography; Excitatory Amino Acid Antagonists; Eye Proteins; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; Intraocular Pressure; Ischemia; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Retina; Retinal Vessels; S100 Calcium Binding Protein G; Thy-1 Antigens

1996
Stimulation of glutamate uptake and Na,K-ATPase activity in rat astrocytes exposed to ischemia-like insults.
    Glia, 1997, Volume: 19, Issue:2

    Topics: Animals; Astrocytes; Cell Hypoxia; Cell Survival; Cells, Cultured; Glucose; Glutamic Acid; Ischemia; Oxygen; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Tritium

1997
Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:4

    Topics: Ammonia; Animals; Body Water; Brain; Disease Models, Animal; Electroencephalography; Glutamic Acid; Hepatic Encephalopathy; Intracranial Pressure; Ischemia; Liver; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1997
Detrimental effects of exogenous glutamate on spinal cord neurons during brief ischemia in vivo.
    The Annals of thoracic surgery, 1997, Volume: 63, Issue:4

    Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Ischemia; Neurons; Paraplegia; Paresis; Quinoxalines; Rabbits; Spinal Cord

1997
The release of amino acids from ischemic retina.
    Experimental eye research, 1997, Volume: 64, Issue:2

    Topics: Alanine; Amino Acids; Animals; Glutamic Acid; Glycine; Ischemia; Male; Ocular Hypertension; Rabbits; Retinal Vessels; Taurine

1997
Microdialysis--a new technique for monitoring local tissue events in the clinic.
    Acta anaesthesiologica Scandinavica. Supplementum, 1997, Volume: 110

    Topics: Animals; Brain; Critical Care; Diabetes Mellitus; Equipment Design; Glucose; Glutamic Acid; Glycerol; Humans; Hypoxia; Infant, Newborn; Intensive Care, Neonatal; Ischemia; Lactates; Microdialysis; Monitoring, Physiologic; Pyruvates; Skin; Urea

1997
[Glutamate neurotoxicity during spinal cord ischemia--development of a delayed-onset paraplegia model].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1997, Volume: 45, Issue:10

    Topics: Animals; Disease Models, Animal; Female; Glutamic Acid; Ischemia; Neurons; Paraplegia; Rabbits; Spinal Cord

1997
Metabolic inhibition increases glutamate susceptibility on a PC12 cell line.
    Journal of neuroscience research, 1998, Feb-01, Volume: 51, Issue:3

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzoquinones; Cell Hypoxia; Disease Susceptibility; Energy Metabolism; Glutamic Acid; Hypoglycemia; Ischemia; Mitochondria; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles; Ubiquinone; Vitamin E

1998
Role of glutamate receptors and voltage-dependent calcium and sodium channels in the extracellular glutamate/aspartate accumulation and subsequent neuronal injury induced by oxygen/glucose deprivation in cultured hippocampal neurons.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1

    Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acid Agonists; Glucose; Glutamic Acid; Hippocampus; Ischemia; L-Lactate Dehydrogenase; Neurons; Oxygen; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Agonists; Sodium Channels

1998
[From the study of biochemical changes in ischemic and reperfused skeletal muscle to the controlled reperfusion of limbs in patients with acute severe ischemia].
    Revue medicale de Liege, 1998, Volume: 53, Issue:2

    Topics: Acute Disease; Aged; Aged, 80 and over; Alkalies; Aspartic Acid; Biochemical Phenomena; Biochemistry; Calcium; Catheterization; Crystalloid Solutions; Embolectomy; Embolism; Female; Femoral Artery; Glutamic Acid; Humans; Infusions, Intra-Arterial; Ischemia; Isotonic Solutions; Leg; Movement; Muscle, Skeletal; Osmolar Concentration; Plasma Substitutes; Pressure; Rehydration Solutions; Reperfusion; Rheology; Sensation; Temperature

1998
Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:6

    Topics: Animals; Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Intraocular Pressure; Ischemia; Male; Memantine; N-Methylaspartate; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Retinal Vessels; Vitreous Body

1998
[Glutamate neurotoxicity during spinal cord ischemia--the neuroprotective effects of adenosine].
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 1998, Volume: 46, Issue:4

    Topics: Adenosine; Animals; Female; Glutamic Acid; Ischemia; Neuroprotective Agents; Rabbits; Spinal Cord

1998
Mechanism of the pathogenesis of glutamate neurotoxicity in retinal ischemia.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:10

    Topics: Animals; Cats; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Intraocular Pressure; Ischemia; Male; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Retina; Retinal Vessels

1998
The effects of moderate hypothermia and intrathecal tetracaine on glutamate concentrations of intrathecal dialysate and neurologic and histopathologic outcome in transient spinal cord ischemia in rabbits.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:1

    Topics: Anesthetics, Local; Animals; Glutamic Acid; Hypothermia, Induced; Injections, Spinal; Ischemia; Rabbits; Reperfusion; Spinal Cord; Tetracaine

1999
Excessive release of [3H]noradrenaline and glutamate in response to simulation of ischemic conditions in rat spinal cord slice preparation: effect of NMDA and AMPA receptor antagonists.
    European journal of pharmacology, 1999, Feb-05, Volume: 366, Issue:2-3

    Topics: Animals; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia; In Vitro Techniques; Ischemia; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stereoisomerism; Tritium

1999
Changes of perilymphatic glutamate and cochlear blood flow following ischemia.
    Acta oto-laryngologica. Supplementum, 1998, Volume: 539

    Topics: Animals; Blood Flow Velocity; Cochlea; Glutamic Acid; Guinea Pigs; Ischemia; Laser-Doppler Flowmetry; Microdialysis; Perilymph; Scala Tympani

1998
Quantitative immunogold cytochemistry reveals sources of glutamate release in inner ear ischemia.
    Acta oto-laryngologica. Supplementum, 1998, Volume: 539

    Topics: Animals; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Immunohistochemistry; Ischemia

1998
Changes of GABA metabolic enzymes in acute retinal ischemia.
    Experimental eye research, 1999, Volume: 69, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Acute Disease; Animals; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Ischemia; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Vessels; Time Factors

1999
The role of glutamine in skeletal muscle ischemia/reperfusion injury in the rat hind limb model.
    American journal of surgery, 1999, Volume: 178, Issue:2

    Topics: Animals; Creatine Kinase; Disease Models, Animal; Glutamic Acid; Glutamine; Glutathione; Hindlimb; Injections, Intraperitoneal; Ischemia; Lipid Peroxidation; Male; Muscle, Skeletal; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Random Allocation; Rats; Rats, Inbred Strains; Reperfusion Injury; Single-Blind Method; Time Factors

1999
The neuroprotective agent MS-153 stimulates glutamate uptake.
    European journal of pharmacology, 1999, Dec-15, Volume: 386, Issue:2-3

    Topics: Amino Acid Transport System X-AG; Amino Acids; Animals; ATP-Binding Cassette Transporters; Biological Transport; COS Cells; Glutamic Acid; Hippocampus; Hypoxia; Ischemia; Male; Neuroprotective Agents; Nicotinic Acids; Oocytes; Potassium; Rats; Rats, Sprague-Dawley; Sodium Channels; Xenopus laevis

1999
Glutamate and kynurenate in the rat central nervous system following treatments with tail ischaemia or diclofenac.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Chromatography, High Pressure Liquid; Diclofenac; Excitatory Amino Acid Antagonists; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Injections, Subcutaneous; Ischemia; Kynurenic Acid; Male; Pain; Rats; Rats, Sprague-Dawley; Tail; Tissue Distribution

2000
The glutathione content of retinal Müller (glial) cells: effect of pathological conditions.
    Neurochemistry international, 2000, Volume: 36, Issue:4-5

    Topics: Animals; Binding, Competitive; Electrophysiology; Glutamic Acid; Glutathione; Guinea Pigs; Hypoxia; Intracellular Membranes; Ischemia; Reference Values; Retina; Retinal Vessels

2000
Spinal cord protection: effect of N-methyl-D-aspartate receptor antagonist MK-801 for spinal cord ischemia in a rabbit model.
    The Kurume medical journal, 2000, Volume: 47, Issue:1

    Topics: Animals; Aspartic Acid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Ischemia; Rabbits; Receptors, N-Methyl-D-Aspartate; Spinal Cord

2000
Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.
    Experimental eye research, 2000, Volume: 70, Issue:5

    Topics: Adenosine; Analysis of Variance; Animals; Aspartic Acid; Bicuculline; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Excitatory Amino Acids; Extracellular Space; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycolysis; Humans; Ischemia; Organophosphorus Compounds; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Retina; Triazines; Triazoles; Xanthines

2000
Gabapentin-lactam (8-aza-spiro[5,4]decan-9-on; GBP-L) inhibits oxygen glucose deprivation-induced [3H]glutmate release and is a neuroprotective agent in amodel of acute retinal ischemia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:1

    Topics: Algorithms; Animals; Aza Compounds; Convulsants; Glucose; Glutamic Acid; Ischemia; Male; Neuroprotective Agents; Oxygen; Rats; Rats, Wistar; Regional Blood Flow; Retina; Retinal Ganglion Cells; Retinal Vessels; Spiro Compounds

2000
alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Brimonidine Tartrate; Chromatography, Liquid; Electroretinography; Extracellular Space; Glutamic Acid; Ischemia; Male; Mass Spectrometry; Quinoxalines; Rats; Rats, Inbred BN; Retina; Retinal Ganglion Cells; Retinal Vessels; Vitreous Body; Yohimbine

2001
Latanoprost exerts neuroprotective activity in vitro and in vivo.
    Experimental eye research, 2001, Volume: 72, Issue:4

    Topics: Analysis of Variance; Animals; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Humans; Ischemia; L-Lactate Dehydrogenase; Latanoprost; Male; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Prostaglandins F, Synthetic; Rats; Rats, Sprague-Dawley; Retina; Spectrophotometry

2001
Characteristics of protective effects of NMDA antagonist and calcium channel antagonist on ischemic calcium accumulation in rat hippocampal CA1 region.
    Brain research bulletin, 2001, Mar-01, Volume: 54, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Hypoxia; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Ischemia; Male; Nifedipine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2001
Design of NAALADase inhibitors: a novel neuroprotective strategy.
    Current medicinal chemistry, 2001, Volume: 8, Issue:8

    Topics: Animals; Carboxylic Acids; Carboxypeptidases; Dipeptides; Drug Design; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Ischemia; Neuroprotective Agents; Phosphinic Acids; Phosphorus; Receptors, Metabotropic Glutamate; Structure-Activity Relationship

2001
Müller cells in retinal health and disease.
    Archivos de la Sociedad Espanola de Oftalmologia, 2000, Volume: 75, Issue:6

    Topics: Ciliary Neurotrophic Factor; Extracellular Matrix; Glutamic Acid; Humans; Ischemia; Neuroglia; Retina; Retinal Vessels

2000
Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia.
    The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42

    Topics: Animals; Botulinum Toxins; Botulinum Toxins, Type A; Cell Death; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Exocytosis; Glutamic Acid; Hippocampus; Immunoblotting; Ischemia; Janus Kinase 2; Neurons; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Erythropoietin; Time Factors; Tyrosine

2001
Intracellular Ca(2+) changes induced by in vitro ischemia in rat retinal slices.
    Experimental eye research, 2001, Volume: 73, Issue:3

    Topics: Animals; Calcium; Cells, Cultured; Female; Fura-2; Glutamic Acid; Ischemia; Male; Microscopy, Fluorescence; Potassium; Rats; Retina; Temperature

2001
In vivo estimation of bioartificial liver with recombinant HepG2 cells using pigs with ischemic liver failure.
    Cell transplantation, 2001, Volume: 10, Issue:4-5

    Topics: Ammonia; Animals; Blood Coagulation; Disease Models, Animal; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Hepatocytes; Humans; Ischemia; Liver; Liver Failure; Liver, Artificial; Recombinant Proteins; Survival Rate; Swine; Transfection; Tumor Cells, Cultured

2001
Differential perturbation of neuronal and glial glutamate transport systems in retinal ischaemia.
    Neurochemistry international, 2001, Volume: 39, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport, Active; Electroretinography; Female; Glutamic Acid; Immunohistochemistry; Ischemia; Neuroglia; Neurons; Perfusion; Rats; Retina; Retinal Vessels

2001
Hypoglycemia induces general neuronal death, whereas hypoxia and glutamate transport blockade lead to selective retinal ganglion cell death in vitro.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:11

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Cell Death; Cells, Cultured; Enzyme Inhibitors; Eye Proteins; Fluorescent Antibody Technique, Indirect; Glutamate-Ammonia Ligase; Glutamic Acid; Hypoglycemia; Hypoxia; Ischemia; Nerve Tissue Proteins; Neurons; Neurotransmitter Uptake Inhibitors; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; Swine

2001
Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29.
    The Journal of biological chemistry, 2002, Mar-08, Volume: 277, Issue:10

    Topics: Animals; Blotting, Western; Brain; Calcium; Calpain; Carrier Proteins; COS Cells; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; DNA; Dose-Response Relationship, Drug; Glutamic Acid; Histidine; Humans; Ionomycin; Ionophores; Ischemia; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Plasmids; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Rats; Sequence Analysis, DNA; Time Factors; Transcription, Genetic; Transfection

2002
Altered glutamine metabolism in rat portal drained viscera and hindquarter during hyperammonemia.
    Gastroenterology, 1992, Volume: 102, Issue:3

    Topics: Amino Acids; Ammonia; Analysis of Variance; Animals; Blood Glucose; Glutamates; Glutamic Acid; Glutamine; Hindlimb; Intestinal Mucosa; Ischemia; Lactates; Lactic Acid; Liver; Male; Muscle Contraction; Muscles; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Regional Blood Flow; Urea; Viscera

1992
Glutamate release in experimental ischaemia of the retina: an approach using microdialysis.
    Journal of neurochemistry, 1992, Volume: 59, Issue:1

    Topics: Amino Acids; Animals; Dialysis; Glutamates; Glutamic Acid; Ischemia; Ketamine; Male; Rabbits; Reperfusion; Retina; Retinal Diseases; Retinal Vessels

1992
Glutamate and anoxic-ischemic cell death in neurons and astrocytes.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Astrocytes; Cell Death; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Humans; Hypoxia; Interneurons; Ischemia; L-Lactate Dehydrogenase; Neurons; Receptors, N-Methyl-D-Aspartate

1992
Intermediary metabolism in renal proximal tubules in the recovery phase of experimental renal ischemia in dogs.
    Renal failure, 1991, Volume: 13, Issue:2-3

    Topics: Alanine; Ammonia; Analysis of Variance; Animals; Dogs; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Ischemia; Ketoglutaric Acids; Kidney; Kidney Tubules, Proximal; Lactates; Lactic Acid; Oxygen Consumption; Rats

1991
Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:2

    Topics: Acute Disease; Ammonia; Animals; Brain; Brain Diseases; Electroencephalography; Glutamates; Glutamic Acid; Ischemia; Lactates; Lactic Acid; Liver Circulation; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Methionine Sulfoximine; Protons; Rats; Rats, Inbred Strains; Urease

1990
Improved quantification of in vivo 1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting.
    Magnetic resonance in medicine, 1990, Volume: 15, Issue:2

    Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Image Enhancement; Ischemia; Liver; Magnetic Resonance Spectroscopy; Rats

1990
Spinal cord ischemia-induced elevation of amino acids: extracellular measurement with microdialysis.
    Neurochemical research, 1990, Volume: 15, Issue:6

    Topics: Amino Acids; Animals; Asparagine; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; Glutamates; Glutamic Acid; Glycine; Ischemia; Kinetics; Rabbits; Spinal Cord; Taurine; Valine

1990
Glutamate neurotoxicity in the cochlea: a possible consequence of ischaemic or anoxic conditions occurring in ageing.
    Acta oto-laryngologica. Supplementum, 1990, Volume: 476

    Topics: Aging; Animals; Cell Hypoxia; Cochlea; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Humans; Ischemia; Kainic Acid; Neurotransmitter Agents; Presbycusis; Vestibulocochlear Nerve

1990