glutamic acid has been researched along with Injuries, Spinal Cord in 114 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.88) | 18.7374 |
1990's | 14 (12.28) | 18.2507 |
2000's | 54 (47.37) | 29.6817 |
2010's | 39 (34.21) | 24.3611 |
2020's | 6 (5.26) | 2.80 |
Authors | Studies |
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Li, L; Liu, J; Tang, J; Wang, H; Zhou, L | 1 |
Dong, H; Guo, Q; Hu, Y; Huang, Y; Li, X; Tao, G; Wang, D; Wang, J; Wang, R; Wang, T; Yue, C | 1 |
Fehlings, MG; Hachem, LD; Hong, J; Mothe, AJ; Tator, CH; Velumian, A | 1 |
Deng, M; Ding, Z; Guo, Q; Huang, J; Kong, Y; Wang, J; Xu, W; Zou, W | 1 |
Abou-Mrad, Z; Alok, K; Alomari, AO; Alomari, SO; Bsat, S; El Houshiemy, MN; Minassian, GB; Moussalem, CK; Omeis, IA | 1 |
De Swert, K; Gilloteaux, J; Janssen, P; Massie, A; Nicaise, C; Rooman, I; Sprimont, L; Van Bulck, M | 1 |
Alizadeh, A; Karimi-Abdolrezaee, S; Kataria, H; Shahsavani, N | 1 |
Bigler, RL; Frost, SB; Larsen, RS; Nagendran, T; Nudo, RJ; Philpot, BD; Taylor, AM | 1 |
Chen, J; Ding, Q; Fan, J; Huang, Y; Jiang, T; Li, W; Liu, D; Liu, Z; Lu, X; Santos, HA; Yin, G; Zhang, W; Zhou, Z | 1 |
Goldshmit, Y; Jona, G; Pinkas-Kramarski, R; Ruban, A; Schmukler, E; Solomon, S | 1 |
Figueiredo, EG; Welling, LC; Welling, MS | 1 |
Abbaszadeh, F; Dargahi, L; Fakhri, S; Jorjani, M | 1 |
Ampatzis, K; Bertuzzi, M; Chang, W | 1 |
Binda, NS; Da Silva, JF; Gabellini, ELA; Gomez, MV; Lavor, MSL; Melo, EG; Melo, MM; Oliveira, CM; Oliveira, KM; Rosado, IR; Silva, CMO | 1 |
Cantet, RJC; Laurella, SL; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN | 1 |
Pham, MH; Srinivas, S; Wali, AR | 1 |
Cai, W; Chen, J; Fan, J; Kong, F; Li, L; Liu, W; Luo, Y; Rong, Y; Tang, P; Wang, J | 1 |
Bethea, JR; Bracchi-Ricard, V; Jayakumar, AR; Johnstone, JT; Liebl, DJ; Morton, PD; Norenberg, MD; Runko, E | 1 |
Ji, XL; Tian, F; Tian, LJ; Xu, LH; Zhao, W | 1 |
Blaber, M; Blaber, SI; Fehlings, MG; Radulovic, M; Scarisbrick, IA; Wu, J; Yoon, H | 1 |
Ahmed, Z; Bendaoud, S; Delva, S; Hawash, A; Leydeker, M; Mohamed, S; Tserlyuk, I; Wagdy, M; Wieraszko, A; Yau, J | 1 |
Assis, LC; de Bem, AF; de Souza, GV; do Valle, RM; dos Santos, AR; Forner, S; Horst, H; Hort, MA; Koepp, J; Martini, AC; Martins, DF; Pizzolatti, MG; Rae, GA; Silva, JC | 1 |
Fukuyama, R; Hara, M; Natsume, A; Nishimura, Y; Sumiyoshi, N; Takeuchi, H; Umebayashi, D; Wakabayashi, T | 1 |
Barreiro-Iglesias, A; Fernández-López, B; Rodicio, MC; Valle-Maroto, SM | 1 |
Asgari, AR; Ghanbari, A; Jorjani, M; Naderi, A; Samandari, R; Zahed, R | 1 |
Gensel, JC; Guan, Z; Lyman, MS; McTigue, DM; Popovich, PG; Puga, DA; Tovar, CA | 1 |
Gill, LC; Gransee, HM; Mantilla, CB; Sieck, GC | 1 |
Bao, G; Chen, J; Cui, Z; Ding, W; Liu, Y; Sun, Y; Wang, S; Wu, C; Xu, G; Zhang, J | 1 |
Diaz-Ruiz, A; Maldonado, V; Montes, S; Ríos, C; Rivera-Espinosa, L; Salgado-Ceballos, H | 1 |
Barreiro-Iglesias, A; Fernández-López, B; Rodicio, MC | 1 |
Gonzalez-Inchauspe, C; Mazzone, GL; Nistri, A; Uchitel, OD; Veeraraghavan, P | 1 |
Abshire, SM; Cameron, AA; Duale, H; Hou, S; Lyttle, TS; Rabchevsky, AG | 1 |
Casas, C; Guzmán-Lenis, MS; Navarro, X; Vallejo, C | 1 |
Echetebu, C; Hulsebosch, CE; Johnson, KM; Liu, S; McAdoo, DJ; Xu, GY; Ye, ZS | 1 |
Dursun, A; Ofluoglu, E; Ozogul, C; Oztanir, N; Pasaoglu, A; Pasaoglu, H; Tufan, K; Uzum, N | 1 |
Hashimoto, M; Kamada, T; Koda, M; Koshizuka, S; Nishihira, J; Nishio, Y; Okawa, A; Onodera, S; Yamazaki, M; Yoshinaga, K | 1 |
Basak, A; Chen, A; Coderre, E; Hameed, S; Ouardouz, M; Rehak, R; Stys, PK; Trapp, BD; Yin, X; Zamponi, GW | 1 |
Manalo, E; Pietri, T; Ryan, J; Saint-Amant, L; Washbourne, P | 1 |
Blesch, A; Bonner, JF; Fischer, I; Neuhuber, B | 1 |
Chen, MC; Liu, YP; Sun, SH; Tzeng, SF; Yang, CS | 1 |
Coderre, TJ; Kumar, N; Laferriere, A; Leavitt, A; Yu, JS | 1 |
Dijkstra, S; Fischer, DF; Gardener, MJ; Keirstead, HS; Nistor, G; Poole, AJ; Rossi, SL; Weiss, JH; Wyatt, T; Yin, HZ | 1 |
Chen, CH; Chen, JK; Chen, MC; Cheng, H; Fang, KM; Hung, SC; Lin, HI; Tzeng, SF; Wu, TJ; Wu, YT; Yang, CS | 1 |
Erschbamer, M; Oberg, J; Olson, L; Sitnikov, R; Spenger, C; Westman, E | 1 |
Bonner, JF; Fischer, I; Kushner, RA; Lepore, AC; Maragakis, NJ; Miller, ME; O'Donnell, J; Paul, C; Rauck, B; Rothstein, JD | 1 |
Oyinbo, CA | 1 |
Haidet-Phillips, A; Kim, AS; Lepore, AC; Maragakis, NJ; O'Banion, CP; O'Donnell, J; Tuteja, A; Yang, EJ | 1 |
Cantoria, MJ; de Leon, RD; See, PA; Singh, H | 1 |
Ahmed, Z; Wieraszko, A | 1 |
Han, X; Jiang, L; Liu, X; Liu, Z; Rong, W; Wang, J; Wei, F; Zhou, H | 1 |
Borgens, RB; Liu-Snyder, P | 1 |
Cardenas, DD; Cruz-Almeida, Y; Felix, ER; Martinez-Arizala, A; Pattany, PM; Perez, S; Widerström-Noga, E | 1 |
Gyimesi-Pelczer, K; Kocsis, B | 1 |
Brown, KM; Wolfe, BB; Wrathall, JR; Yasuda, RP | 1 |
Azbill, RD; Mu, X; Springer, JE | 3 |
Chandler, MJ; Farber, JP; Foreman, RD; Qin, C | 1 |
Sharma, HS; Sjöquist, PO | 1 |
Ito, S; Kitano, T; Kojima, H; Mabuchi, T; Matsumura, S; Minami, T; Nagano, T; Okuda-Ashitaka, E | 1 |
Hausmann, ON | 1 |
Ashitomi, K; Hatano, T; Miyazato, M; Nishijima, S; Ogawa, Y; Sugaya, K | 1 |
Eisenberg, M; Hsu, JY; Noble-Haeusslein, LJ; Werb, Z; Whetstone, WD | 1 |
Stys, PK | 1 |
Tseng, GF; Wang, YJ | 1 |
Hughes, MG; Hulsebosch, CE; McAdoo, DJ; Xu, GY; Ye, Z | 1 |
Fehlings, MG; Park, E; Velumian, AA | 1 |
Foreman, RD; Kranenburg, A; Qin, C | 1 |
Ashitomi, K; Miyazato, M; Morozumi, M; Nishijima, S; Ogawa, Y; Sugaya, K | 1 |
Clifton, C; Fullwood, S; Hughes, MG; Hulsebosch, CE; McAdoo, DJ; Nie, L; Shah, B | 1 |
Cain, L; Hughes, MG; McAdoo, DJ; Xu, GY; Zhang, L | 1 |
Boyd, MR; Horinek, DF; Jackson, AW; McClellan, AD | 1 |
Chen, WY; Liang, WM; Tsai, PJ; Tzeng, SF; Yang, CS | 1 |
de Groat, WC; Yoshimura, N | 1 |
Barlati, S; Brunelli, G; Pizzi, M; Spano, P | 1 |
Geuna, S | 1 |
Kitzman, P | 1 |
Alcaraz-Zubeldia, M; Diaz-Ruiz, A; Maldonado, V; Montes, S; Ríos, C; Salgado-Ceballos, H; Tristan, L | 1 |
Fellin, T; Halassa, MM; Haydon, PG | 1 |
Chen, GD; Chen, MJ; Huang, PC; Liao, JM; Lin, TB; Liou, YM; Pan, SF; Peng, HY; Shyu, JC; Tung, KC | 1 |
Cain, LD; Echetebu, C; Hughes, MG; Hulsebosch, CE; Johnson, K; McAdoo, DJ; Nie, L; Xu, GY | 1 |
Aikawa, J; Bonatto, SJ; Brito, G; Fernandes, LC; Lissa, MD; Nogata, C; Nunes, EA; Pchevozniki, AI; Pchevozniki, AM; Tanhoffer, RA; Yamazaki, RK | 1 |
Eisner, F; Engele, J; Lehmann, C | 1 |
Bu, H; Fan, ZL; Guo, YS; Li, B; Li, CY; Li, Z; Liu, XY; Ren, WB; Sun, MM; Wu, DX; Wu, SY; Zhang, L | 1 |
Irani, DN; Prow, NA | 1 |
Hájek, M; Likavcanová, K; Syková, E; Urdzíková, L | 1 |
Ha, KY; Kim, YH; Kwon, SE; Rhyu, KW | 1 |
McAdoo, DJ; Wu, P | 1 |
Calandra, R; Coirini, H; De Nicola, AF; Gonzalez Deniselle, MC; Gonzalez, S | 1 |
Caiozzo, VJ; Gardner, VO; Takeda, H | 1 |
Goshgarian, HG; Tai, Q | 1 |
Shapiro, S | 1 |
Craenen, G; Grants, I; Jeftinija, S; Lucas, JH | 1 |
Azbill, RD; Begley, JG; Mark, RJ; Mattson, MP; Springer, JE; Waeg, G | 1 |
Cassam, AK; Krassioukov, AV; Krenz, NR; Llewellyn-Smith, IJ; Weaver, LC | 1 |
Ishikawa, T; Kawai, S; Marsala, M; Sakabe, T; Taguchi, T; Yamamoto, K | 1 |
de Castro, R; Hughes, MG; McAdoo, DJ; Robak, G; Xu, GY | 1 |
Alessandri, B; Bullock, R | 1 |
Li, S; Mealing, GA; Morley, P; Stys, PK | 1 |
Liu, D; McAdoo, DJ; Pan, E; Xu, GY | 1 |
Hughes, MG; McAdoo, DJ; Robak, G; Xu, GY | 2 |
Muñana, KR; Olby, NJ; Papich, MG; Sharp, NJ | 1 |
Hughes, MG; McAdoo, DJ; Price, EM; Robak, G; Xu, G | 1 |
Cullheim, S; Lindå, H; Ornung, G; Ottersen, OP; Risling, M; Shupliakov, O; Storm-Mathisen, J | 1 |
Choi, D | 1 |
Hulsebosch, CE; Johnson, KM; McAdoo, DJ; Mills, CD; Xu, GY | 1 |
Hauben, E; Kipnis, J; Schori, H; Schwartz, M; Shaked, I; Yoles, E | 1 |
Beattie, MS; Bresnahan, JC; Hermann, GE; Rogers, RC | 1 |
Kiyoshima, T; Matsumoto, M; Nakakimura, K; Ohtake, K; Oka, S; Sakabe, T | 1 |
Hulsebosch, CE; McAdoo, DJ; Mills, CD; Xu, GY | 1 |
Fullwood, SD; Hulsebosch, CE; McAdoo, DJ; Mills, CD; Vera-Portocarrero, LP; Westlund, KN; Ye, Z | 1 |
Bird, ET; Boone, TB; Chancellor, MB; Smith, CP; Somogyi, GT | 1 |
Daly, MP; Demediuk, P; Faden, AI | 1 |
14 review(s) available for glutamic acid and Injuries, Spinal Cord
Article | Year |
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Role of connexins in spinal cord injury: An update.
Topics: Animals; Astrocytes; Axons; Connexins; Gap Junctions; Glutamic Acid; Humans; Spinal Cord; Spinal Cord Injuries | 2020 |
Scavenger and Spinal Cord Injury: Light at the End of the Tunnel.
Topics: Animals; Astrocytes; Glutamic Acid; Humans; Inflammation Mediators; Spinal Cord Injuries | 2018 |
Efficacy of riluzole in the treatment of spinal cord injury: a systematic review of the literature.
Topics: Adolescent; Adult; Aged; Animals; Biological Availability; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Middle Aged; Neuroprotective Agents; Rabbits; Rats; Recovery of Function; Riluzole; Spinal Cord Injuries; Trauma Severity Indices; Treatment Outcome; Young Adult | 2019 |
Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons.
Topics: Animals; Cervical Cord; Glutamic Acid; Humans; Motor Neurons; Nerve Growth Factors; Phrenic Nerve; Recovery of Function; Respiration; Signal Transduction; Spinal Cord Injuries | 2016 |
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade.
Topics: Apoptosis; Calcium; Disease Progression; Glutamic Acid; Humans; Immune System Diseases; Lipid Peroxidation; Nerve Degeneration; Nervous System Diseases; Neuroprotective Agents; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2011 |
Understanding secondary injury.
Topics: Apoptosis; Brain Injuries; Calcium Channels; Cell Death; Edema; Glutamic Acid; Hemorrhage; Humans; Ischemia; Lipid Peroxidation; Neurons; Reperfusion Injury; Sodium Channels; Spinal Cord Injuries; Stroke; Trauma, Nervous System; Wounds and Injuries; Zinc | 2012 |
Post-traumatic inflammation following spinal cord injury.
Topics: Animals; Calcium; Cell Death; Free Radicals; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Inflammation; Mitochondria; Neuroglia; Neurons; Neurotoxins; Nitric Oxide; Spinal Cord Injuries; Wallerian Degeneration | 2003 |
White matter injury mechanisms.
Topics: Adenosine Triphosphate; Animals; Axons; Biological Transport; Brain; Brain Injuries; Calcium; Cytosol; Glutamic Acid; Humans; Hypoxia; Ions; Microscopy, Confocal; Models, Biological; Muscles; Optic Nerve; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Spinal Cord Injuries; Time Factors | 2004 |
The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration.
Topics: Apoptosis; Fatty Acids, Nonesterified; Free Radicals; Glutamic Acid; Humans; Receptors, Glutamate; Retrograde Degeneration; Spinal Cord Injuries | 2004 |
Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury.
Topics: Adrenergic Fibers; Afferent Pathways; Animals; Brain; Efferent Pathways; Glutamic Acid; Humans; Interneurons; Nerve Growth Factors; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels; Reflex; Sodium Channels; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Tachykinins; Urinary Bladder; Urination Disorders; Vasoactive Intestinal Peptide | 2006 |
Glutamatergic innervation of rat skeletal muscle by supraspinal neurons: a new paradigm in spinal cord injury repair.
Topics: Animals; Brain; Disease Models, Animal; Efferent Pathways; Glutamic Acid; Humans; Muscle, Skeletal; Nerve Regeneration; Neuromuscular Junction; Neuronal Plasticity; Peripheral Nerves; Rats; Recovery of Function; Spinal Cord Injuries | 2006 |
Microdialysis in central nervous system disorders and their treatment.
Topics: Animals; Brain Injuries; Calibration; Central Nervous System Diseases; Glutamic Acid; Hydroxyl Radical; Microdialysis; Neurons; Pain; Reactive Oxygen Species; Spinal Cord Injuries; Zinc | 2008 |
Neurotransmission by neurons that use serotonin, noradrenaline, glutamate, glycine, and gamma-aminobutyric acid in the normal and injured spinal cord.
Topics: Animals; Ganglia, Spinal; Glutamic Acid; Glycine; Humans; Interneurons; Motor Neurons; Neural Inhibition; Norepinephrine; Serotonin; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission | 1997 |
Glutamate and its receptors in the pathophysiology of brain and spinal cord injuries.
Topics: Animals; Brain Injuries; Glutamic Acid; Humans; Receptors, Glutamate; Spinal Cord Injuries | 1998 |
100 other study(ies) available for glutamic acid and Injuries, Spinal Cord
Article | Year |
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Effects of C5a and Receptor CD88 on Glutamate and N-Methyl-D-Aspartic Acid Receptor Expression in the Mouse Model of Optic Neuromyelitis.
Topics: Animals; Disease Models, Animal; Glutamic Acid; Humans; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuromyelitis Optica; Receptor, Anaphylatoxin C5a; Spinal Cord Injuries | 2022 |
An In Situ Assembled Trapping Gel Repairs Spinal Cord Injury by Capturing Glutamate and Free Calcium Ions.
Topics: Animals; Calcium; Glutamic Acid; Ions; Neurons; Rats; Spinal Cord Injuries | 2023 |
Excitotoxic glutamate levels drive spinal cord ependymal stem cell proliferation and fate specification through CP-AMPAR signaling.
Topics: Calcium; Cell Proliferation; Glutamic Acid; Humans; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries | 2023 |
SNAP-25 Contributes to Neuropathic Pain by Regulation of VGLuT2 Expression in Rats.
Topics: Animals; Astrocytes; Botulinum Toxins, Type A; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Glutamic Acid; Hyperalgesia; Male; Neuralgia; Protein Kinases; Rats; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Synaptosomal-Associated Protein 25; Up-Regulation; Vesicular Glutamate Transport Protein 2 | 2019 |
Cystine-glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice.
Topics: Amino Acid Transport System y+; Animals; Cystine; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Recovery of Function; Spinal Cord Injuries | 2021 |
Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms.
Topics: Animals; Caspases; Cells, Cultured; Female; Glutamic Acid; Neuregulin-1; Neuroprotection; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2021 |
Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.
Topics: Animals; Axotomy; Dendritic Spines; Embryo, Mammalian; Gene Expression; Glutamic Acid; Microfluidic Analytical Techniques; Motor Cortex; Netrin-1; Neuronal Plasticity; Primary Cell Culture; Pyramidal Cells; Rats, Sprague-Dawley; Spinal Cord Injuries; Synapses | 2017 |
Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity.
Topics: Animals; Apoptosis; Glutamic Acid; Neurons; Rats; Spinal Cord Injuries | 2018 |
Blood Glutamate Scavenger as a Novel Neuroprotective Treatment in Spinal Cord Injury.
Topics: Animals; Aspartate Aminotransferase, Cytoplasmic; Female; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Recombinant Proteins; Spinal Cord Injuries | 2018 |
Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury.
Topics: Animals; Cytokines; Disease Models, Animal; Glutamic Acid; Inflammation; Male; Motor Disorders; Neuralgia; Neuroimmunomodulation; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Recovery of Function; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Xanthophylls | 2018 |
Adult spinal motoneurons change their neurotransmitter phenotype to control locomotion.
Topics: Aging; Animals; Behavior, Animal; Glutamic Acid; Locomotion; Motor Neurons; Neuromuscular Junction; Neurotransmitter Agents; Phenotype; Spinal Cord Injuries; Synapses; Zebrafish | 2018 |
Conotoxin MVIIA improves cell viability and antioxidant system after spinal cord injury in rats.
Topics: Animals; Antioxidants; Cell Survival; Conotoxins; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutamic Acid; Lipid Peroxidation; Locomotion; Mitochondria; Rats; Reactive Oxygen Species; Spinal Cord Injuries; Time Factors | 2018 |
Lidocaine protects neurons of the spinal cord in an excitotoxicity model.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Lidocaine; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2019 |
Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy.
Topics: Animals; Apoptosis; Autophagy; Beclin-1; Cells, Cultured; Cytokines; Disease Models, Animal; Extracellular Vesicles; Fetus; Glutamic Acid; Inflammation; Locomotion; Macrophages; Male; Mice; Microtubule-Associated Proteins; Neural Stem Cells; Neurons; Rats, Sprague-Dawley; Spinal Cord Injuries | 2019 |
Reduced extracellular zinc levels facilitate glutamate-mediated oligodendrocyte death after trauma.
Topics: Animals; Cell Death; Cells, Cultured; Disease Models, Animal; Extracellular Fluid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Transgenic; NF-kappa B; Oligodendroglia; Spinal Cord Injuries; Zinc | 2013 |
The neuroprotective mechanism of puerarin treatment of acute spinal cord injury in rats.
Topics: Acute Disease; Animals; Apoptosis; Glutamic Acid; Isoflavones; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reperfusion Injury; RNA, Messenger; Spinal Cord; Spinal Cord Injuries | 2013 |
Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.
Topics: Animals; Cells, Cultured; Cerebellum; Female; Glutamic Acid; Kallikreins; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Neurons; Neurotoxicity Syndromes; Receptor, PAR-1; Receptor, PAR-2; RNA; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Thrombin | 2013 |
The effects of 15 Hz trans-spinal magnetic stimulation on locomotor control in mice with chronic contusive spinal cord injury.
Topics: Animals; Behavior, Animal; Chronic Disease; D-Aspartic Acid; Glutamic Acid; Locomotion; Magnetic Field Therapy; Male; Mice; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Spine | 2013 |
Neuroprotective effect of the proanthocyanidin-rich fraction in experimental model of spinal cord injury.
Topics: Animals; Antioxidants; Cell Death; Croton; Disease Models, Animal; Ganglia, Spinal; Glutamic Acid; Male; Movement; Muscle Strength; Neuroprotective Agents; Phytotherapy; Plant Bark; Plant Extracts; Proanthocyanidins; Rats, Wistar; Reactive Oxygen Species; Receptors, Glutamate; Spinal Cord Injuries | 2014 |
Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity.
Topics: Animals; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Gap Junctions; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Immunohistochemistry; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord Injuries | 2014 |
Neuronal release and successful astrocyte uptake of aminoacidergic neurotransmitters after spinal cord injury in lampreys.
Topics: Animals; Astrocytes; Axons; Fish Proteins; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; Keratins; Lampreys; Microscopy, Confocal; Neurons; Neurotransmitter Agents; Photomicrography; Spinal Cord Injuries; Spinal Cord Regeneration; Time Factors | 2014 |
Estradiol attenuates spinal cord injury-related central pain by decreasing glutamate levels in thalamic VPL nucleus in male rats.
Topics: Analgesics; Animals; Disease Models, Animal; Estradiol; Glutamic Acid; Hyperalgesia; Male; Neuralgia; Pain Threshold; Rats; Rats, Wistar; Spinal Cord Injuries; Ventral Thalamic Nuclei | 2014 |
Stress exacerbates neuron loss and microglia proliferation in a rat model of excitotoxic lower motor neuron injury.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Microglia; Motor Neurons; Rats; Rats, Sprague-Dawley; Restraint, Physical; Spinal Cord; Spinal Cord Injuries; Stress, Psychological | 2015 |
The importance of EHD1 in neurite outgrowth contributing to the functional recovery after spinal cord injury.
Topics: Animals; Animals, Newborn; Brain; Calcium-Binding Proteins; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Immunoprecipitation; In Vitro Techniques; Male; Microfilament Proteins; Nerve Tissue Proteins; Neuronal Outgrowth; Neurons; Rats; Rats, Sprague-Dawley; Receptor, trkA; Recovery of Function; RNA, Small Interfering; Spinal Cord Injuries; Time Factors; Transfection; Vesicular Transport Proteins | 2016 |
Enzyme activities involved in the glutamate-glutamine cycle are altered to reduce glutamate after spinal cord injury in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme Activation; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors | 2016 |
Anatomical recovery of the spinal glutamatergic system following a complete spinal cord injury in lampreys.
Topics: Animals; Glutamic Acid; Lampreys; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration | 2016 |
ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Animals; Cell Death; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Indoles; Kainic Acid; Mice; Neuroglia; Neurons; Protons; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Tissue Culture Techniques | 2017 |
Plasticity of lumbosacral propriospinal neurons is associated with the development of autonomic dysreflexia after thoracic spinal cord transection.
Topics: Afferent Pathways; Animals; Antibodies; Autonomic Dysreflexia; Biotin; Choline O-Acetyltransferase; Dextrans; Disease Models, Animal; Enkephalins; Female; gamma-Aminobutyric Acid; Glutamic Acid; Lumbosacral Region; Nerve Fibers; Neuronal Plasticity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries | 2008 |
Analysis of FK506-mediated protection in an organotypic model of spinal cord damage: heat shock protein 70 levels are modulated in microglial cells.
Topics: Animals; Animals, Newborn; Calcineurin; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ethidium; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Microglia; Organ Culture Techniques; Rats; Spinal Cord Injuries; Tacrolimus; Time Factors; Tubulin | 2008 |
Regulation of interleukin-1beta by the interleukin-1 receptor antagonist in the glutamate-injured spinal cord: endogenous neuroprotection.
Topics: Animals; Cytoprotection; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gait Disorders, Neurologic; Glutamic Acid; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Male; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Recovery of Function; Spinal Cord Injuries; Up-Regulation | 2008 |
Ultrastructure protection and attenuation of lipid peroxidation after blockade of presynaptic release of glutamate by lamotrigine in experimental spinal cord injury.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Female; Glutamic Acid; Glutathione Peroxidase; Laminectomy; Lamotrigine; Lipid Peroxidation; Malondialdehyde; Microscopy, Electron, Transmission; Presynaptic Terminals; Random Allocation; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase; Triazines | 2008 |
Deletion of macrophage migration inhibitory factor attenuates neuronal death and promotes functional recovery after compression-induced spinal cord injury in mice.
Topics: Analysis of Variance; Animals; Caspase 3; Cell Death; Cells, Cultured; Cerebellum; DNA-Binding Proteins; Extremities; Female; Glutamic Acid; Immunohistochemistry; Locomotion; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred BALB C; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Recovery of Function; Spinal Cord Compression; Spinal Cord Injuries; Time Factors | 2009 |
Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors.
Topics: Animals; Axons; Calcium; Calcium Channels, L-Type; Cysteine; Egtazic Acid; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydroxocobalamin; Male; Microscopy, Confocal; Myoglobin; Nerve Fibers, Myelinated; Nitric Oxide; PDZ Domains; Peptides; Protein Multimerization; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Ryanodine; Spinal Cord Injuries; Spinal Nerve Roots | 2009 |
Glutamate drives the touch response through a rostral loop in the spinal cord of zebrafish embryos.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Electrophysiology; Embryo, Nonmammalian; Escape Reaction; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Neural Pathways; Neurons; Receptors, AMPA; Reflex; Spinal Cord; Spinal Cord Injuries; Swimming; Synapses; Zebrafish | 2009 |
Promoting directional axon growth from neural progenitors grafted into the injured spinal cord.
Topics: Aging; Animals; Axons; Brain-Derived Neurotrophic Factor; Cell Enlargement; Female; gamma-Aminobutyric Acid; Genetic Vectors; Glutamic Acid; Lentivirus; Nerve Regeneration; Neuroglia; Neurons; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Spinal Cord Injuries; Stem Cell Transplantation; Stem Cells | 2010 |
Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Benzoxazoles; Calcium; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Transporter 1; Female; Gene Expression Regulation; Glutamic Acid; Humans; Injections, Spinal; Neurons; Phosphatidylinositol 3-Kinases; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Spinal Cord Injuries; Transfection | 2010 |
Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate.
Topics: Analgesics; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Electrochemistry; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Male; Microdialysis; Pain Measurement; Pain Threshold; Physical Stimulation; Pregabalin; Rats; Rats, Long-Evans; Sciatica; Spinal Cord; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors | 2010 |
Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord.
Topics: Animals; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Female; Glutamic Acid; Humans; Immunohistochemistry; Motor Neurons; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2010 |
Effects of combinatorial treatment with pituitary adenylate cyclase activating peptide and human mesenchymal stem cells on spinal cord tissue repair.
Topics: Animals; Astrocytes; Cell Survival; Cell- and Tissue-Based Therapy; Glutamic Acid; Humans; Mesenchymal Stem Cells; Microglia; Models, Biological; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration; Superoxide Dismutase | 2010 |
1H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord.
Topics: Animals; Brain; Female; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2011 |
Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.
Topics: Animals; Astrocytes; Cell Proliferation; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Mice; Mice, Transgenic; Promoter Regions, Genetic; Spinal Cord; Spinal Cord Injuries; Time Factors | 2011 |
Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury.
Topics: Animals; Astrocytes; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2; Gliosis; Glutamic Acid; Mice; Mice, Knockout; Spinal Cord; Spinal Cord Injuries | 2011 |
Adaptations in glutamate and glycine content within the lumbar spinal cord are associated with the generation of novel gait patterns in rats following neonatal spinal cord transection.
Topics: Animals; Female; Gait; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Locomotion; Lumbar Vertebrae; Motor Activity; Motor Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Vesicular Glutamate Transport Protein 1 | 2011 |
Trans-spinal direct current enhances corticospinal output and stimulation-evoked release of glutamate analog, D-2,3-³H-aspartic acid.
Topics: Animals; Aspartic Acid; Behavior, Animal; Calcium; Cerebral Cortex; Disease Models, Animal; Electric Stimulation Therapy; Evoked Potentials, Motor; Female; Glutamic Acid; Long-Term Potentiation; Male; Mice; Motor Activity; Muscle Contraction; Muscle Strength; Muscle, Skeletal; Pyramidal Tracts; Spinal Cord Injuries; Synaptic Transmission; Time Factors | 2012 |
17β-estradiol attenuates neural cell apoptosis through inhibition of JNK phosphorylation in SCI rats and excitotoxicity induced by glutamate in vitro.
Topics: Analysis of Variance; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Estradiol; Female; Glutamic Acid; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury.
Topics: Adult; Choline; Creatine; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Neuralgia; Pain Management; Pain Measurement; Predictive Value of Tests; Prognosis; Reproducibility of Results; Severity of Illness Index; Spinal Cord Injuries | 2013 |
Coherent sympathetic nerve activity in different postganglionic nerves after spinal cord transection in the cat.
Topics: Animals; Cats; Decerebrate State; Electrophysiology; Glutamic Acid; Heart Conduction System; Kidney; Nerve Net; Spinal Cord Injuries; Spinal Nerves; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System | 2002 |
Quantitative measurement of glutamate receptor subunit protein expression in the postnatal rat spinal cord.
Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Down-Regulation; Glutamic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Up-Regulation | 2002 |
NBQX treatment improves mitochondrial function and reduces oxidative events after spinal cord injury.
Topics: Animals; Dizocilpine Maleate; Female; Glucose; Glutamic Acid; Injections, Spinal; Lipid Peroxidation; Mitochondria; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Synaptosomes; Thiobarbituric Acid Reactive Substances; Thoracic Vertebrae | 2002 |
Chemical activation of C(1)-C(2) spinal neurons modulates activity of thoracic respiratory interneurons in rats.
Topics: Animals; Cervical Vertebrae; Electric Stimulation; Electrophysiology; Glutamic Acid; Interneurons; Male; Rats; Rats, Sprague-Dawley; Respiratory System; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae | 2002 |
A new antioxidant compound H-290/51 modulates glutamate and GABA immunoreactivity in the rat spinal cord following trauma.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Edema; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neuroprotective Agents; Permeability; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2002 |
Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production.
Topics: Aminoquinolines; Animals; Benzamides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluorescein; Fluorescence; Fluorescent Dyes; Functional Laterality; Glutamic Acid; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Knockout; NADPH Dehydrogenase; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nociceptin; Opioid Peptides; Peptide Fragments; Reaction Time; Spinal Cord; Spinal Cord Injuries; Time Factors | 2003 |
Inhibitory effect of intrathecal glycine on the micturition reflex in normal and spinal cord injury rats.
Topics: Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Female; Glutamic Acid; Glycine; Glycine Agents; Injections, Spinal; Lumbosacral Region; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Reflex; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Strychnine; Urinary Bladder; Urination | 2003 |
Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing.
Topics: Animals; Astrocytes; Blood Vessels; Blood-Brain Barrier; Excitatory Amino Acid Transporter 2; Gliosis; Glutamic Acid; Luciferases; Macrophages; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Spinal Cord; Spinal Cord Injuries; Wound Healing | 2003 |
Spinal axonal injury transiently elevates the level of metabotropic glutamate receptor 5, but not 1, in cord-projection central neurons.
Topics: Animals; Axons; Disease Models, Animal; Efferent Pathways; Female; Glutamic Acid; Immunohistochemistry; Neurotoxins; Rats; Rats, Wistar; Reaction Time; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Red Nucleus; Retrograde Degeneration; Spinal Cord Injuries; Synaptic Transmission; Up-Regulation | 2004 |
Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord.
Topics: Animals; Cell Count; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries; Time Factors | 2004 |
Descending modulation of thoracic visceroreceptive transmission by C1-C2 spinal neurons.
Topics: Action Potentials; Afferent Pathways; Animals; Bradykinin; Cervical Vertebrae; Drug Interactions; Esophagus; Glutamic Acid; Male; Neural Inhibition; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2004 |
Dietary glycine inhibits bladder activity in normal rats and rats with spinal cord injury.
Topics: Animals; Blood-Brain Barrier; Body Weight; Female; Glutamic Acid; Glycine; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Reflex; Spinal Cord; Spinal Cord Injuries; Urinary Bladder; Urine | 2005 |
The effect of glutamate receptor blockers on glutamate release following spinal cord injury. Lack of evidence for an ongoing feedback cascade of damage --> glutamate release --> damage --> glutamate release --> etc.
Topics: Animals; Excitatory Amino Acid Antagonists; Feedback, Physiological; Glutamic Acid; Male; Neurons; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Single-Blind Method; Sodium Channel Blockers; Spinal Cord; Spinal Cord Injuries | 2005 |
Administration of glutamate into the spinal cord at extracellular concentrations reached post-injury causes functional impairments.
Topics: Animals; Dose-Response Relationship, Drug; Extracellular Fluid; Gait Disorders, Neurologic; Glutamic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2005 |
Disruption of left-right reciprocal coupling in the spinal cord of larval lamprey abolishes brain-initiated locomotor activity.
Topics: Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Brain; Electromyography; Escape Reaction; Evoked Potentials, Motor; Functional Laterality; Glutamic Acid; In Vitro Techniques; Interneurons; Larva; Motor Activity; Muscles; Neural Inhibition; Periodicity; Petromyzon; Physical Stimulation; Psychomotor Performance; Pyramidal Tracts; Spinal Cord; Spinal Cord Injuries | 2005 |
Experimental spinal cord injury induced an increase of extracellular ascorbic acid concentration in anesthetized rats: a microdialysis study.
Topics: Anesthesia; Animals; Ascorbic Acid; Extracellular Space; Glutamic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2005 |
Spinal cord injury treatment by induction of a shift from cholinergic to glutamatergic innervation of muscle fibers.
Topics: Acetylcholine; Animals; Efferent Pathways; Glutamic Acid; Humans; Muscle, Skeletal; Nerve Regeneration; Neuromuscular Junction; Peripheral Nerves; Phenotype; Spinal Cord Injuries; Tissue Transplantation | 2007 |
VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat.
Topics: Animals; Behavior, Animal; Disease Progression; Female; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Immunohistochemistry; Microscopy, Confocal; Motor Neurons; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Sacrococcygeal Region; Spinal Cord Injuries; Tail; Vesicular Glutamate Transport Protein 1 | 2007 |
Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats.
Topics: Animals; Aspartic Acid; Citrulline; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Rats; Rats, Wistar; Spinal Cord Injuries; Taurine | 2007 |
The tripartite synapse: roles for gliotransmission in health and disease.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium Signaling; Epilepsy; Glutamic Acid; Humans; Models, Neurological; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Spinal Cord Injuries; Synapses; Synaptic Transmission | 2007 |
Spinal glutamatergic NMDA-dependent pelvic nerve-to-external urethra sphincter reflex potentiation caused by a mechanical stimulation in anesthetized rats.
Topics: Action Potentials; Anesthesia; Animals; Dilatation; Electromyography; Female; GABA Agonists; GABA Antagonists; Glutamic Acid; Injections, Spinal; Muscle, Skeletal; Pelvis; Peripheral Nerves; Physical Stimulation; Pressure; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord Injuries; Urethra | 2007 |
Serum albumin improves recovery from spinal cord injury.
Topics: Animals; Cells, Cultured; Glutamic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Recovery of Function; Serum Albumin; Spinal Cord Injuries | 2007 |
Glutamine concentration and immune response of spinal cord-injured rats.
Topics: Animals; Bacterial Infections; Biomarkers; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Lymphocyte Activation; Macrophages; Male; Metabolism; Muscle, Skeletal; Muscular Atrophy; Paralysis; Peptide Hydrolases; Predictive Value of Tests; Rats; Rats, Wistar; Sepsis; Spinal Cord Injuries; T-Lymphocytes | 2007 |
Role of endothelins as mediators of injury-induced alterations of glial glutamate turnover.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Brain; Brain Injuries; Bucladesine; Cells, Cultured; Cerebral Cortex; Endothelins; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glutamate-Ammonia Ligase; Glutamic Acid; In Vitro Techniques; Neuroglia; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2008 |
The neuroprotective potential of phase II enzyme inducer on motor neuron survival in traumatic spinal cord injury in vitro.
Topics: Animals; Animals, Newborn; Cell Survival; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Glutamic Acid; Heme Oxygenase (Decyclizing); Hydroquinones; Mitochondria; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; NF-E2-Related Factor 2; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Sulfhydryl Compounds; Thiones | 2008 |
The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis.
Topics: Acute Disease; Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport, Active; Cell Survival; Cytokines; Encephalitis, Viral; Glutamic Acid; Inflammation Mediators; Interleukin-1beta; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Neurons; Spinal Cord Injuries | 2008 |
Metabolic changes in the thalamus after spinal cord injury followed by proton MR spectroscopy.
Topics: Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Glutamic Acid; Hindlimb; Hot Temperature; Inositol; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Wistar; Spinal Cord Injuries; Thalamus | 2008 |
Pregabalin as a neuroprotector after spinal cord injury in rats.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Apoptosis; gamma-Aminobutyric Acid; Glutamic Acid; Inflammation; Male; Methylprednisolone; Microglia; Minocycline; Models, Animal; Pregabalin; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2008 |
Time-dependent effects of dexamethasone on glutamate binding, ornithine decarboxylase activity and polyamine levels in the transected spinal cord.
Topics: Animals; Dexamethasone; Glucocorticoids; Glutamic Acid; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Time Factors | 1995 |
A functional in vitro model for studying the cellular and molecular basis of spinal cord injury.
Topics: Animals; Animals, Newborn; Brain Stem; Cell Death; Glutamates; Glutamic Acid; Hindlimb; Locomotion; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries | 1993 |
Ultrastructural quantitative analysis of glutamatergic and GABAergic synaptic terminals in the phrenic nucleus after spinal cord injury.
Topics: Animals; Female; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Microscopy, Electron; Motor Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 1996 |
The role of excitatory amino acids in hypothermic injury to mammalian spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cell Death; Cells, Cultured; Cold Temperature; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Mice; Neurons; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord; Spinal Cord Injuries | 1996 |
4-hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake.
Topics: Aldehydes; Amino Acid Transport System X-AG; Animals; Antibody Specificity; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Western; Cell Death; Cross-Linking Reagents; Female; Free Radicals; Glutamic Acid; Immunohistochemistry; Lipid Peroxidation; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Spinal Cord Injuries; Wounds and Injuries | 1997 |
Glutamate- and GABA-immunoreactive synapses on sympathetic preganglionic neurons caudal to a spinal cord transection in rats.
Topics: Adrenal Medulla; Animals; Axonal Transport; Dendrites; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Glutamic Acid; Male; Microscopy, Immunoelectron; Neurons; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Synapses | 1997 |
The hydroxyl radical scavenger Nicaraven inhibits glutamate release after spinal injury in rats.
Topics: Animals; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Hypothermia, Induced; Male; Niacinamide; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord; Spinal Cord Injuries; Time Factors | 1998 |
Considerations in the determination by microdialysis of resting extracellular amino acid concentrations and release upon spinal cord injury.
Topics: Amino Acids; Animals; Blood-Brain Barrier; Evans Blue; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Fibers; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 1998 |
Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport.
Topics: Action Potentials; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Axons; Carrier Proteins; Cell Hypoxia; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Myelin Sheath; Patch-Clamp Techniques; Pressure; Rats; Rats, Long-Evans; Receptors, AMPA; Sodium; Spinal Cord; Spinal Cord Injuries; Stress, Mechanical; Symporters | 1999 |
Neurotoxicity of glutamate at the concentration released upon spinal cord injury.
Topics: Animals; Aspartic Acid; Contusions; Glutamic Acid; Male; Microdialysis; Nerve Degeneration; Neurotoxins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 1999 |
Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Citrulline; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine; Time Factors | 1999 |
Chronic and acute compressive spinal cord lesions in dogs due to intervertebral disc herniation are associated with elevation in lumbar cerebrospinal fluid glutamate concentration.
Topics: Acute Disease; Animals; Chronic Disease; Dogs; Glutamic Acid; Intervertebral Disc Displacement; Lumbar Vertebrae; Lumbosacral Region; Osmolar Concentration; Reference Values; Spinal Cord Injuries; Thoracic Vertebrae | 1999 |
Adenosine release upon spinal cord injury.
Topics: Adenosine; Animals; Glutamic Acid; Microdialysis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Theophylline | 2000 |
Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord.
Topics: Animals; Glutamic Acid; Kainic Acid; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2000 |
Riluzole improves measures of oxidative stress following traumatic spinal cord injury.
Topics: Animals; Female; Glutamic Acid; Mitochondria; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Long-Evans; Rhodamines; Riluzole; Spinal Cord Injuries; Synaptosomes; Thiobarbituric Acid Reactive Substances | 2000 |
Ultrastructural evidence for a preferential elimination of glutamate-immunoreactive synaptic terminals from spinal motoneurons after intramedullary axotomy.
Topics: Animals; Axotomy; Cats; Dendrites; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Microscopy, Electron; Microtomy; Motor Neurons; Nerve Regeneration; Neuronal Plasticity; Neurotoxins; Presynaptic Terminals; Spinal Cord; Spinal Cord Injuries | 2000 |
Riluzole and methylprednisolone combined treatment improves functional recovery in traumatic spinal cord injury.
Topics: Animals; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Gait Disorders, Neurologic; Glucocorticoids; Glutamic Acid; Locomotion; Methylprednisolone; Myelin Sheath; Rats; Rats, Long-Evans; Recovery of Function; Riluzole; Spinal Cord; Spinal Cord Injuries | 2000 |
Stroke.
Topics: Animals; Apoptosis; Cycloheximide; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Intracranial Embolism; Necrosis; Neuroprotective Agents; Plasminogen Activators; Spinal Cord Injuries; Stroke; Tissue Plasminogen Activator | 2000 |
AIDA reduces glutamate release and attenuates mechanical allodynia after spinal cord injury.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperalgesia; Indans; Male; Mechanoreceptors; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord Injuries | 2000 |
Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response.
Topics: Animals; Autoimmunity; Cell Count; Cell Survival; Central Nervous System; Disease Models, Animal; Drug Administration Routes; Encephalomyelitis, Autoimmune, Experimental; Female; Genetic Predisposition to Disease; Glutamic Acid; Immunity, Cellular; Injections; Male; Mice; Mice, Inbred Strains; Mice, Nude; Nerve Crush; Neurons; Optic Nerve Injuries; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Retinal Ganglion Cells; Species Specificity; Spinal Cord Injuries; T-Lymphocytes; Wounds, Nonpenetrating | 2001 |
Tumor necrosis factor-alpha induces cFOS and strongly potentiates glutamate-mediated cell death in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Death; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microglia; Neurons; Neurotoxins; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2001 |
The addition of epinephrine to tetracaine injected intrathecally sustains an increase in glutamate concentrations in the cerebrospinal fluid and worsens neuronal injury.
Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Epinephrine; Glutamic Acid; Hemodynamics; Injections, Spinal; Microdialysis; Neurons; Rabbits; Spinal Cord Injuries; Tetracaine; Vasoconstrictor Agents | 2001 |
Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat.
Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Cord Injuries | 2001 |
Rapid changes in expression of glutamate transporters after spinal cord injury.
Topics: Amino Acid Transport System X-AG; Animals; Blotting, Western; Carrier Proteins; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Homeostasis; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Symporters | 2002 |
Neurogenic bladder model for spinal cord injury: spinal cord microdialysis and chronic urodynamics.
Topics: Animals; Catheters, Indwelling; Disease Models, Animal; Female; Glutamic Acid; Glycine; Microdialysis; Neurochemistry; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Urinary Bladder; Urinary Bladder, Neurogenic | 2002 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |