glutamic acid and Injuries, Spinal Cord

glutamic acid has been researched along with Injuries, Spinal Cord in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.88)18.7374
1990's14 (12.28)18.2507
2000's54 (47.37)29.6817
2010's39 (34.21)24.3611
2020's6 (5.26)2.80

Authors

AuthorsStudies
Li, L; Liu, J; Tang, J; Wang, H; Zhou, L1
Dong, H; Guo, Q; Hu, Y; Huang, Y; Li, X; Tao, G; Wang, D; Wang, J; Wang, R; Wang, T; Yue, C1
Fehlings, MG; Hachem, LD; Hong, J; Mothe, AJ; Tator, CH; Velumian, A1
Deng, M; Ding, Z; Guo, Q; Huang, J; Kong, Y; Wang, J; Xu, W; Zou, W1
Abou-Mrad, Z; Alok, K; Alomari, AO; Alomari, SO; Bsat, S; El Houshiemy, MN; Minassian, GB; Moussalem, CK; Omeis, IA1
De Swert, K; Gilloteaux, J; Janssen, P; Massie, A; Nicaise, C; Rooman, I; Sprimont, L; Van Bulck, M1
Alizadeh, A; Karimi-Abdolrezaee, S; Kataria, H; Shahsavani, N1
Bigler, RL; Frost, SB; Larsen, RS; Nagendran, T; Nudo, RJ; Philpot, BD; Taylor, AM1
Chen, J; Ding, Q; Fan, J; Huang, Y; Jiang, T; Li, W; Liu, D; Liu, Z; Lu, X; Santos, HA; Yin, G; Zhang, W; Zhou, Z1
Goldshmit, Y; Jona, G; Pinkas-Kramarski, R; Ruban, A; Schmukler, E; Solomon, S1
Figueiredo, EG; Welling, LC; Welling, MS1
Abbaszadeh, F; Dargahi, L; Fakhri, S; Jorjani, M1
Ampatzis, K; Bertuzzi, M; Chang, W1
Binda, NS; Da Silva, JF; Gabellini, ELA; Gomez, MV; Lavor, MSL; Melo, EG; Melo, MM; Oliveira, CM; Oliveira, KM; Rosado, IR; Silva, CMO1
Cantet, RJC; Laurella, SL; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN1
Pham, MH; Srinivas, S; Wali, AR1
Cai, W; Chen, J; Fan, J; Kong, F; Li, L; Liu, W; Luo, Y; Rong, Y; Tang, P; Wang, J1
Bethea, JR; Bracchi-Ricard, V; Jayakumar, AR; Johnstone, JT; Liebl, DJ; Morton, PD; Norenberg, MD; Runko, E1
Ji, XL; Tian, F; Tian, LJ; Xu, LH; Zhao, W1
Blaber, M; Blaber, SI; Fehlings, MG; Radulovic, M; Scarisbrick, IA; Wu, J; Yoon, H1
Ahmed, Z; Bendaoud, S; Delva, S; Hawash, A; Leydeker, M; Mohamed, S; Tserlyuk, I; Wagdy, M; Wieraszko, A; Yau, J1
Assis, LC; de Bem, AF; de Souza, GV; do Valle, RM; dos Santos, AR; Forner, S; Horst, H; Hort, MA; Koepp, J; Martini, AC; Martins, DF; Pizzolatti, MG; Rae, GA; Silva, JC1
Fukuyama, R; Hara, M; Natsume, A; Nishimura, Y; Sumiyoshi, N; Takeuchi, H; Umebayashi, D; Wakabayashi, T1
Barreiro-Iglesias, A; Fernández-López, B; Rodicio, MC; Valle-Maroto, SM1
Asgari, AR; Ghanbari, A; Jorjani, M; Naderi, A; Samandari, R; Zahed, R1
Gensel, JC; Guan, Z; Lyman, MS; McTigue, DM; Popovich, PG; Puga, DA; Tovar, CA1
Gill, LC; Gransee, HM; Mantilla, CB; Sieck, GC1
Bao, G; Chen, J; Cui, Z; Ding, W; Liu, Y; Sun, Y; Wang, S; Wu, C; Xu, G; Zhang, J1
Diaz-Ruiz, A; Maldonado, V; Montes, S; Ríos, C; Rivera-Espinosa, L; Salgado-Ceballos, H1
Barreiro-Iglesias, A; Fernández-López, B; Rodicio, MC1
Gonzalez-Inchauspe, C; Mazzone, GL; Nistri, A; Uchitel, OD; Veeraraghavan, P1
Abshire, SM; Cameron, AA; Duale, H; Hou, S; Lyttle, TS; Rabchevsky, AG1
Casas, C; Guzmán-Lenis, MS; Navarro, X; Vallejo, C1
Echetebu, C; Hulsebosch, CE; Johnson, KM; Liu, S; McAdoo, DJ; Xu, GY; Ye, ZS1
Dursun, A; Ofluoglu, E; Ozogul, C; Oztanir, N; Pasaoglu, A; Pasaoglu, H; Tufan, K; Uzum, N1
Hashimoto, M; Kamada, T; Koda, M; Koshizuka, S; Nishihira, J; Nishio, Y; Okawa, A; Onodera, S; Yamazaki, M; Yoshinaga, K1
Basak, A; Chen, A; Coderre, E; Hameed, S; Ouardouz, M; Rehak, R; Stys, PK; Trapp, BD; Yin, X; Zamponi, GW1
Manalo, E; Pietri, T; Ryan, J; Saint-Amant, L; Washbourne, P1
Blesch, A; Bonner, JF; Fischer, I; Neuhuber, B1
Chen, MC; Liu, YP; Sun, SH; Tzeng, SF; Yang, CS1
Coderre, TJ; Kumar, N; Laferriere, A; Leavitt, A; Yu, JS1
Dijkstra, S; Fischer, DF; Gardener, MJ; Keirstead, HS; Nistor, G; Poole, AJ; Rossi, SL; Weiss, JH; Wyatt, T; Yin, HZ1
Chen, CH; Chen, JK; Chen, MC; Cheng, H; Fang, KM; Hung, SC; Lin, HI; Tzeng, SF; Wu, TJ; Wu, YT; Yang, CS1
Erschbamer, M; Oberg, J; Olson, L; Sitnikov, R; Spenger, C; Westman, E1
Bonner, JF; Fischer, I; Kushner, RA; Lepore, AC; Maragakis, NJ; Miller, ME; O'Donnell, J; Paul, C; Rauck, B; Rothstein, JD1
Oyinbo, CA1
Haidet-Phillips, A; Kim, AS; Lepore, AC; Maragakis, NJ; O'Banion, CP; O'Donnell, J; Tuteja, A; Yang, EJ1
Cantoria, MJ; de Leon, RD; See, PA; Singh, H1
Ahmed, Z; Wieraszko, A1
Han, X; Jiang, L; Liu, X; Liu, Z; Rong, W; Wang, J; Wei, F; Zhou, H1
Borgens, RB; Liu-Snyder, P1
Cardenas, DD; Cruz-Almeida, Y; Felix, ER; Martinez-Arizala, A; Pattany, PM; Perez, S; Widerström-Noga, E1
Gyimesi-Pelczer, K; Kocsis, B1
Brown, KM; Wolfe, BB; Wrathall, JR; Yasuda, RP1
Azbill, RD; Mu, X; Springer, JE3
Chandler, MJ; Farber, JP; Foreman, RD; Qin, C1
Sharma, HS; Sjöquist, PO1
Ito, S; Kitano, T; Kojima, H; Mabuchi, T; Matsumura, S; Minami, T; Nagano, T; Okuda-Ashitaka, E1
Hausmann, ON1
Ashitomi, K; Hatano, T; Miyazato, M; Nishijima, S; Ogawa, Y; Sugaya, K1
Eisenberg, M; Hsu, JY; Noble-Haeusslein, LJ; Werb, Z; Whetstone, WD1
Stys, PK1
Tseng, GF; Wang, YJ1
Hughes, MG; Hulsebosch, CE; McAdoo, DJ; Xu, GY; Ye, Z1
Fehlings, MG; Park, E; Velumian, AA1
Foreman, RD; Kranenburg, A; Qin, C1
Ashitomi, K; Miyazato, M; Morozumi, M; Nishijima, S; Ogawa, Y; Sugaya, K1
Clifton, C; Fullwood, S; Hughes, MG; Hulsebosch, CE; McAdoo, DJ; Nie, L; Shah, B1
Cain, L; Hughes, MG; McAdoo, DJ; Xu, GY; Zhang, L1
Boyd, MR; Horinek, DF; Jackson, AW; McClellan, AD1
Chen, WY; Liang, WM; Tsai, PJ; Tzeng, SF; Yang, CS1
de Groat, WC; Yoshimura, N1
Barlati, S; Brunelli, G; Pizzi, M; Spano, P1
Geuna, S1
Kitzman, P1
Alcaraz-Zubeldia, M; Diaz-Ruiz, A; Maldonado, V; Montes, S; Ríos, C; Salgado-Ceballos, H; Tristan, L1
Fellin, T; Halassa, MM; Haydon, PG1
Chen, GD; Chen, MJ; Huang, PC; Liao, JM; Lin, TB; Liou, YM; Pan, SF; Peng, HY; Shyu, JC; Tung, KC1
Cain, LD; Echetebu, C; Hughes, MG; Hulsebosch, CE; Johnson, K; McAdoo, DJ; Nie, L; Xu, GY1
Aikawa, J; Bonatto, SJ; Brito, G; Fernandes, LC; Lissa, MD; Nogata, C; Nunes, EA; Pchevozniki, AI; Pchevozniki, AM; Tanhoffer, RA; Yamazaki, RK1
Eisner, F; Engele, J; Lehmann, C1
Bu, H; Fan, ZL; Guo, YS; Li, B; Li, CY; Li, Z; Liu, XY; Ren, WB; Sun, MM; Wu, DX; Wu, SY; Zhang, L1
Irani, DN; Prow, NA1
Hájek, M; Likavcanová, K; Syková, E; Urdzíková, L1
Ha, KY; Kim, YH; Kwon, SE; Rhyu, KW1
McAdoo, DJ; Wu, P1
Calandra, R; Coirini, H; De Nicola, AF; Gonzalez Deniselle, MC; Gonzalez, S1
Caiozzo, VJ; Gardner, VO; Takeda, H1
Goshgarian, HG; Tai, Q1
Shapiro, S1
Craenen, G; Grants, I; Jeftinija, S; Lucas, JH1
Azbill, RD; Begley, JG; Mark, RJ; Mattson, MP; Springer, JE; Waeg, G1
Cassam, AK; Krassioukov, AV; Krenz, NR; Llewellyn-Smith, IJ; Weaver, LC1
Ishikawa, T; Kawai, S; Marsala, M; Sakabe, T; Taguchi, T; Yamamoto, K1
de Castro, R; Hughes, MG; McAdoo, DJ; Robak, G; Xu, GY1
Alessandri, B; Bullock, R1
Li, S; Mealing, GA; Morley, P; Stys, PK1
Liu, D; McAdoo, DJ; Pan, E; Xu, GY1
Hughes, MG; McAdoo, DJ; Robak, G; Xu, GY2
Muñana, KR; Olby, NJ; Papich, MG; Sharp, NJ1
Hughes, MG; McAdoo, DJ; Price, EM; Robak, G; Xu, G1
Cullheim, S; Lindå, H; Ornung, G; Ottersen, OP; Risling, M; Shupliakov, O; Storm-Mathisen, J1
Choi, D1
Hulsebosch, CE; Johnson, KM; McAdoo, DJ; Mills, CD; Xu, GY1
Hauben, E; Kipnis, J; Schori, H; Schwartz, M; Shaked, I; Yoles, E1
Beattie, MS; Bresnahan, JC; Hermann, GE; Rogers, RC1
Kiyoshima, T; Matsumoto, M; Nakakimura, K; Ohtake, K; Oka, S; Sakabe, T1
Hulsebosch, CE; McAdoo, DJ; Mills, CD; Xu, GY1
Fullwood, SD; Hulsebosch, CE; McAdoo, DJ; Mills, CD; Vera-Portocarrero, LP; Westlund, KN; Ye, Z1
Bird, ET; Boone, TB; Chancellor, MB; Smith, CP; Somogyi, GT1
Daly, MP; Demediuk, P; Faden, AI1

Reviews

14 review(s) available for glutamic acid and Injuries, Spinal Cord

ArticleYear
Role of connexins in spinal cord injury: An update.
    Clinical neurology and neurosurgery, 2020, Volume: 197

    Topics: Animals; Astrocytes; Axons; Connexins; Gap Junctions; Glutamic Acid; Humans; Spinal Cord; Spinal Cord Injuries

2020
Scavenger and Spinal Cord Injury: Light at the End of the Tunnel.
    World neurosurgery, 2018, Volume: 114

    Topics: Animals; Astrocytes; Glutamic Acid; Humans; Inflammation Mediators; Spinal Cord Injuries

2018
Efficacy of riluzole in the treatment of spinal cord injury: a systematic review of the literature.
    Neurosurgical focus, 2019, 03-01, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Biological Availability; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Middle Aged; Neuroprotective Agents; Rabbits; Rats; Recovery of Function; Riluzole; Spinal Cord Injuries; Trauma Severity Indices; Treatment Outcome; Young Adult

2019
Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons.
    Respiratory physiology & neurobiology, 2016, Volume: 226

    Topics: Animals; Cervical Cord; Glutamic Acid; Humans; Motor Neurons; Nerve Growth Factors; Phrenic Nerve; Recovery of Function; Respiration; Signal Transduction; Spinal Cord Injuries

2016
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade.
    Acta neurobiologiae experimentalis, 2011, Volume: 71, Issue:2

    Topics: Apoptosis; Calcium; Disease Progression; Glutamic Acid; Humans; Immune System Diseases; Lipid Peroxidation; Nerve Degeneration; Nervous System Diseases; Neuroprotective Agents; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2011
Understanding secondary injury.
    The Quarterly review of biology, 2012, Volume: 87, Issue:2

    Topics: Apoptosis; Brain Injuries; Calcium Channels; Cell Death; Edema; Glutamic Acid; Hemorrhage; Humans; Ischemia; Lipid Peroxidation; Neurons; Reperfusion Injury; Sodium Channels; Spinal Cord Injuries; Stroke; Trauma, Nervous System; Wounds and Injuries; Zinc

2012
Post-traumatic inflammation following spinal cord injury.
    Spinal cord, 2003, Volume: 41, Issue:7

    Topics: Animals; Calcium; Cell Death; Free Radicals; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Inflammation; Mitochondria; Neuroglia; Neurons; Neurotoxins; Nitric Oxide; Spinal Cord Injuries; Wallerian Degeneration

2003
White matter injury mechanisms.
    Current molecular medicine, 2004, Volume: 4, Issue:2

    Topics: Adenosine Triphosphate; Animals; Axons; Biological Transport; Brain; Brain Injuries; Calcium; Cytosol; Glutamic Acid; Humans; Hypoxia; Ions; Microscopy, Confocal; Models, Biological; Muscles; Optic Nerve; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Spinal Cord Injuries; Time Factors

2004
The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration.
    Journal of neurotrauma, 2004, Volume: 21, Issue:6

    Topics: Apoptosis; Fatty Acids, Nonesterified; Free Radicals; Glutamic Acid; Humans; Receptors, Glutamate; Retrograde Degeneration; Spinal Cord Injuries

2004
Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury.
    Progress in brain research, 2006, Volume: 152

    Topics: Adrenergic Fibers; Afferent Pathways; Animals; Brain; Efferent Pathways; Glutamic Acid; Humans; Interneurons; Nerve Growth Factors; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channels; Reflex; Sodium Channels; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Tachykinins; Urinary Bladder; Urination Disorders; Vasoactive Intestinal Peptide

2006
Glutamatergic innervation of rat skeletal muscle by supraspinal neurons: a new paradigm in spinal cord injury repair.
    Current opinion in neurobiology, 2006, Volume: 16, Issue:3

    Topics: Animals; Brain; Disease Models, Animal; Efferent Pathways; Glutamic Acid; Humans; Muscle, Skeletal; Nerve Regeneration; Neuromuscular Junction; Neuronal Plasticity; Peripheral Nerves; Rats; Recovery of Function; Spinal Cord Injuries

2006
Microdialysis in central nervous system disorders and their treatment.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:2

    Topics: Animals; Brain Injuries; Calibration; Central Nervous System Diseases; Glutamic Acid; Hydroxyl Radical; Microdialysis; Neurons; Pain; Reactive Oxygen Species; Spinal Cord Injuries; Zinc

2008
Neurotransmission by neurons that use serotonin, noradrenaline, glutamate, glycine, and gamma-aminobutyric acid in the normal and injured spinal cord.
    Neurosurgery, 1997, Volume: 40, Issue:1

    Topics: Animals; Ganglia, Spinal; Glutamic Acid; Glycine; Humans; Interneurons; Motor Neurons; Neural Inhibition; Norepinephrine; Serotonin; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission

1997
Glutamate and its receptors in the pathophysiology of brain and spinal cord injuries.
    Progress in brain research, 1998, Volume: 116

    Topics: Animals; Brain Injuries; Glutamic Acid; Humans; Receptors, Glutamate; Spinal Cord Injuries

1998

Other Studies

100 other study(ies) available for glutamic acid and Injuries, Spinal Cord

ArticleYear
Effects of C5a and Receptor CD88 on Glutamate and N-Methyl-D-Aspartic Acid Receptor Expression in the Mouse Model of Optic Neuromyelitis.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Animals; Disease Models, Animal; Glutamic Acid; Humans; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuromyelitis Optica; Receptor, Anaphylatoxin C5a; Spinal Cord Injuries

2022
An In Situ Assembled Trapping Gel Repairs Spinal Cord Injury by Capturing Glutamate and Free Calcium Ions.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:16

    Topics: Animals; Calcium; Glutamic Acid; Ions; Neurons; Rats; Spinal Cord Injuries

2023
Excitotoxic glutamate levels drive spinal cord ependymal stem cell proliferation and fate specification through CP-AMPAR signaling.
    Stem cell reports, 2023, 03-14, Volume: 18, Issue:3

    Topics: Calcium; Cell Proliferation; Glutamic Acid; Humans; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries

2023
SNAP-25 Contributes to Neuropathic Pain by Regulation of VGLuT2 Expression in Rats.
    Neuroscience, 2019, 12-15, Volume: 423

    Topics: Animals; Astrocytes; Botulinum Toxins, Type A; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Glutamic Acid; Hyperalgesia; Male; Neuralgia; Protein Kinases; Rats; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Synaptosomal-Associated Protein 25; Up-Regulation; Vesicular Glutamate Transport Protein 2

2019
Cystine-glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice.
    Scientific reports, 2021, 06-09, Volume: 11, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Cystine; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Recovery of Function; Spinal Cord Injuries

2021
Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms.
    Experimental neurology, 2021, Volume: 345

    Topics: Animals; Caspases; Cells, Cultured; Female; Glutamic Acid; Neuregulin-1; Neuroprotection; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2021
Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.
    Nature communications, 2017, 09-20, Volume: 8, Issue:1

    Topics: Animals; Axotomy; Dendritic Spines; Embryo, Mammalian; Gene Expression; Glutamic Acid; Microfluidic Analytical Techniques; Motor Cortex; Netrin-1; Neuronal Plasticity; Primary Cell Culture; Pyramidal Cells; Rats, Sprague-Dawley; Spinal Cord Injuries; Synapses

2017
Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity.
    Advanced materials (Deerfield Beach, Fla.), 2018, Volume: 30, Issue:14

    Topics: Animals; Apoptosis; Glutamic Acid; Neurons; Rats; Spinal Cord Injuries

2018
Blood Glutamate Scavenger as a Novel Neuroprotective Treatment in Spinal Cord Injury.
    Journal of neurotrauma, 2018, 11-01, Volume: 35, Issue:21

    Topics: Animals; Aspartate Aminotransferase, Cytoplasmic; Female; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Recombinant Proteins; Spinal Cord Injuries

2018
Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury.
    Brain research bulletin, 2018, Volume: 143

    Topics: Animals; Cytokines; Disease Models, Animal; Glutamic Acid; Inflammation; Male; Motor Disorders; Neuralgia; Neuroimmunomodulation; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Recovery of Function; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Xanthophylls

2018
Adult spinal motoneurons change their neurotransmitter phenotype to control locomotion.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-16, Volume: 115, Issue:42

    Topics: Aging; Animals; Behavior, Animal; Glutamic Acid; Locomotion; Motor Neurons; Neuromuscular Junction; Neurotransmitter Agents; Phenotype; Spinal Cord Injuries; Synapses; Zebrafish

2018
Conotoxin MVIIA improves cell viability and antioxidant system after spinal cord injury in rats.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Animals; Antioxidants; Cell Survival; Conotoxins; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutamic Acid; Lipid Peroxidation; Locomotion; Mitochondria; Rats; Reactive Oxygen Species; Spinal Cord Injuries; Time Factors

2018
Lidocaine protects neurons of the spinal cord in an excitotoxicity model.
    Neuroscience letters, 2019, 04-17, Volume: 698

    Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Lidocaine; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2019
Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy.
    Cell death & disease, 2019, 04-18, Volume: 10, Issue:5

    Topics: Animals; Apoptosis; Autophagy; Beclin-1; Cells, Cultured; Cytokines; Disease Models, Animal; Extracellular Vesicles; Fetus; Glutamic Acid; Inflammation; Locomotion; Macrophages; Male; Mice; Microtubule-Associated Proteins; Neural Stem Cells; Neurons; Rats, Sprague-Dawley; Spinal Cord Injuries

2019
Reduced extracellular zinc levels facilitate glutamate-mediated oligodendrocyte death after trauma.
    Journal of neuroscience research, 2013, Volume: 91, Issue:6

    Topics: Animals; Cell Death; Cells, Cultured; Disease Models, Animal; Extracellular Fluid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Transgenic; NF-kappa B; Oligodendroglia; Spinal Cord Injuries; Zinc

2013
The neuroprotective mechanism of puerarin treatment of acute spinal cord injury in rats.
    Neuroscience letters, 2013, May-24, Volume: 543

    Topics: Acute Disease; Animals; Apoptosis; Glutamic Acid; Isoflavones; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reperfusion Injury; RNA, Messenger; Spinal Cord; Spinal Cord Injuries

2013
Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.
    Journal of neurochemistry, 2013, Volume: 127, Issue:2

    Topics: Animals; Cells, Cultured; Cerebellum; Female; Glutamic Acid; Kallikreins; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Neurons; Neurotoxicity Syndromes; Receptor, PAR-1; Receptor, PAR-2; RNA; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Thrombin

2013
The effects of 15 Hz trans-spinal magnetic stimulation on locomotor control in mice with chronic contusive spinal cord injury.
    Electromagnetic biology and medicine, 2013, Volume: 32, Issue:2

    Topics: Animals; Behavior, Animal; Chronic Disease; D-Aspartic Acid; Glutamic Acid; Locomotion; Magnetic Field Therapy; Male; Mice; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Spine

2013
Neuroprotective effect of the proanthocyanidin-rich fraction in experimental model of spinal cord injury.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:5

    Topics: Animals; Antioxidants; Cell Death; Croton; Disease Models, Animal; Ganglia, Spinal; Glutamic Acid; Male; Movement; Muscle Strength; Neuroprotective Agents; Phytotherapy; Plant Bark; Plant Extracts; Proanthocyanidins; Rats, Wistar; Reactive Oxygen Species; Receptors, Glutamate; Spinal Cord Injuries

2014
Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity.
    Journal of neurotrauma, 2014, Dec-15, Volume: 31, Issue:24

    Topics: Animals; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Gap Junctions; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Immunohistochemistry; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord Injuries

2014
Neuronal release and successful astrocyte uptake of aminoacidergic neurotransmitters after spinal cord injury in lampreys.
    Glia, 2014, Volume: 62, Issue:8

    Topics: Animals; Astrocytes; Axons; Fish Proteins; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; Keratins; Lampreys; Microscopy, Confocal; Neurons; Neurotransmitter Agents; Photomicrography; Spinal Cord Injuries; Spinal Cord Regeneration; Time Factors

2014
Estradiol attenuates spinal cord injury-related central pain by decreasing glutamate levels in thalamic VPL nucleus in male rats.
    Metabolic brain disease, 2014, Volume: 29, Issue:3

    Topics: Analgesics; Animals; Disease Models, Animal; Estradiol; Glutamic Acid; Hyperalgesia; Male; Neuralgia; Pain Threshold; Rats; Rats, Wistar; Spinal Cord Injuries; Ventral Thalamic Nuclei

2014
Stress exacerbates neuron loss and microglia proliferation in a rat model of excitotoxic lower motor neuron injury.
    Brain, behavior, and immunity, 2015, Volume: 49

    Topics: Animals; Cell Proliferation; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Microglia; Motor Neurons; Rats; Rats, Sprague-Dawley; Restraint, Physical; Spinal Cord; Spinal Cord Injuries; Stress, Psychological

2015
The importance of EHD1 in neurite outgrowth contributing to the functional recovery after spinal cord injury.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2016, Volume: 52

    Topics: Animals; Animals, Newborn; Brain; Calcium-Binding Proteins; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Immunoprecipitation; In Vitro Techniques; Male; Microfilament Proteins; Nerve Tissue Proteins; Neuronal Outgrowth; Neurons; Rats; Rats, Sprague-Dawley; Receptor, trkA; Recovery of Function; RNA, Small Interfering; Spinal Cord Injuries; Time Factors; Transfection; Vesicular Transport Proteins

2016
Enzyme activities involved in the glutamate-glutamine cycle are altered to reduce glutamate after spinal cord injury in rats.
    Neuroreport, 2016, Dec-14, Volume: 27, Issue:18

    Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme Activation; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors

2016
Anatomical recovery of the spinal glutamatergic system following a complete spinal cord injury in lampreys.
    Scientific reports, 2016, 11-25, Volume: 6

    Topics: Animals; Glutamic Acid; Lampreys; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration

2016
ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury.
    Neuroscience, 2017, 02-20, Volume: 343

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Animals; Cell Death; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Indoles; Kainic Acid; Mice; Neuroglia; Neurons; Protons; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Tissue Culture Techniques

2017
Plasticity of lumbosacral propriospinal neurons is associated with the development of autonomic dysreflexia after thoracic spinal cord transection.
    The Journal of comparative neurology, 2008, Aug-01, Volume: 509, Issue:4

    Topics: Afferent Pathways; Animals; Antibodies; Autonomic Dysreflexia; Biotin; Choline O-Acetyltransferase; Dextrans; Disease Models, Animal; Enkephalins; Female; gamma-Aminobutyric Acid; Glutamic Acid; Lumbosacral Region; Nerve Fibers; Neuronal Plasticity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

2008
Analysis of FK506-mediated protection in an organotypic model of spinal cord damage: heat shock protein 70 levels are modulated in microglial cells.
    Neuroscience, 2008, Jul-31, Volume: 155, Issue:1

    Topics: Animals; Animals, Newborn; Calcineurin; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ethidium; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Microglia; Organ Culture Techniques; Rats; Spinal Cord Injuries; Tacrolimus; Time Factors; Tubulin

2008
Regulation of interleukin-1beta by the interleukin-1 receptor antagonist in the glutamate-injured spinal cord: endogenous neuroprotection.
    Brain research, 2008, Sep-22, Volume: 1231

    Topics: Animals; Cytoprotection; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gait Disorders, Neurologic; Glutamic Acid; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Male; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Recovery of Function; Spinal Cord Injuries; Up-Regulation

2008
Ultrastructure protection and attenuation of lipid peroxidation after blockade of presynaptic release of glutamate by lamotrigine in experimental spinal cord injury.
    Neurosurgical focus, 2008, Volume: 25, Issue:5

    Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Female; Glutamic Acid; Glutathione Peroxidase; Laminectomy; Lamotrigine; Lipid Peroxidation; Malondialdehyde; Microscopy, Electron, Transmission; Presynaptic Terminals; Random Allocation; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase; Triazines

2008
Deletion of macrophage migration inhibitory factor attenuates neuronal death and promotes functional recovery after compression-induced spinal cord injury in mice.
    Acta neuropathologica, 2009, Volume: 117, Issue:3

    Topics: Analysis of Variance; Animals; Caspase 3; Cell Death; Cells, Cultured; Cerebellum; DNA-Binding Proteins; Extremities; Female; Glutamic Acid; Immunohistochemistry; Locomotion; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred BALB C; Mice, Knockout; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Recovery of Function; Spinal Cord Compression; Spinal Cord Injuries; Time Factors

2009
Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors.
    Annals of neurology, 2009, Volume: 65, Issue:2

    Topics: Animals; Axons; Calcium; Calcium Channels, L-Type; Cysteine; Egtazic Acid; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydroxocobalamin; Male; Microscopy, Confocal; Myoglobin; Nerve Fibers, Myelinated; Nitric Oxide; PDZ Domains; Peptides; Protein Multimerization; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Ryanodine; Spinal Cord Injuries; Spinal Nerve Roots

2009
Glutamate drives the touch response through a rostral loop in the spinal cord of zebrafish embryos.
    Developmental neurobiology, 2009, Volume: 69, Issue:12

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Electrophysiology; Embryo, Nonmammalian; Escape Reaction; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Neural Pathways; Neurons; Receptors, AMPA; Reflex; Spinal Cord; Spinal Cord Injuries; Swimming; Synapses; Zebrafish

2009
Promoting directional axon growth from neural progenitors grafted into the injured spinal cord.
    Journal of neuroscience research, 2010, May-01, Volume: 88, Issue:6

    Topics: Aging; Animals; Axons; Brain-Derived Neurotrophic Factor; Cell Enlargement; Female; gamma-Aminobutyric Acid; Genetic Vectors; Glutamic Acid; Lentivirus; Nerve Regeneration; Neuroglia; Neurons; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Spinal Cord Injuries; Stem Cell Transplantation; Stem Cells

2010
Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling.
    Journal of neurochemistry, 2010, Volume: 113, Issue:1

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Benzoxazoles; Calcium; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Transporter 1; Female; Gene Expression Regulation; Glutamic Acid; Humans; Injections, Spinal; Neurons; Phosphatidylinositol 3-Kinases; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Spinal Cord Injuries; Transfection

2010
Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate.
    Journal of neurochemistry, 2010, Volume: 113, Issue:2

    Topics: Analgesics; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Electrochemistry; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Male; Microdialysis; Pain Measurement; Pain Threshold; Physical Stimulation; Pregabalin; Rats; Rats, Long-Evans; Sciatica; Spinal Cord; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors

2010
Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord.
    PloS one, 2010, Jul-29, Volume: 5, Issue:7

    Topics: Animals; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Female; Glutamic Acid; Humans; Immunohistochemistry; Motor Neurons; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2010
Effects of combinatorial treatment with pituitary adenylate cyclase activating peptide and human mesenchymal stem cells on spinal cord tissue repair.
    PloS one, 2010, Dec-20, Volume: 5, Issue:12

    Topics: Animals; Astrocytes; Cell Survival; Cell- and Tissue-Based Therapy; Glutamic Acid; Humans; Mesenchymal Stem Cells; Microglia; Models, Biological; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration; Superoxide Dismutase

2010
1H-MRS in spinal cord injury: acute and chronic metabolite alterations in rat brain and lumbar spinal cord.
    The European journal of neuroscience, 2011, Volume: 33, Issue:4

    Topics: Animals; Brain; Female; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2011
Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.
    Journal of neuroscience research, 2011, Volume: 89, Issue:7

    Topics: Animals; Astrocytes; Cell Proliferation; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Mice; Mice, Transgenic; Promoter Regions, Genetic; Spinal Cord; Spinal Cord Injuries; Time Factors

2011
Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury.
    Glia, 2011, Volume: 59, Issue:12

    Topics: Animals; Astrocytes; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 2; Gliosis; Glutamic Acid; Mice; Mice, Knockout; Spinal Cord; Spinal Cord Injuries

2011
Adaptations in glutamate and glycine content within the lumbar spinal cord are associated with the generation of novel gait patterns in rats following neonatal spinal cord transection.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Dec-14, Volume: 31, Issue:50

    Topics: Animals; Female; Gait; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Locomotion; Lumbar Vertebrae; Motor Activity; Motor Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Vesicular Glutamate Transport Protein 1

2011
Trans-spinal direct current enhances corticospinal output and stimulation-evoked release of glutamate analog, D-2,3-³H-aspartic acid.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:9

    Topics: Animals; Aspartic Acid; Behavior, Animal; Calcium; Cerebral Cortex; Disease Models, Animal; Electric Stimulation Therapy; Evoked Potentials, Motor; Female; Glutamic Acid; Long-Term Potentiation; Male; Mice; Motor Activity; Muscle Contraction; Muscle Strength; Muscle, Skeletal; Pyramidal Tracts; Spinal Cord Injuries; Synaptic Transmission; Time Factors

2012
17β-estradiol attenuates neural cell apoptosis through inhibition of JNK phosphorylation in SCI rats and excitotoxicity induced by glutamate in vitro.
    The International journal of neuroscience, 2012, Volume: 122, Issue:7

    Topics: Analysis of Variance; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Estradiol; Female; Glutamic Acid; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tetrazolium Salts; Thiazoles; Time Factors

2012
Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury.
    Pain, 2013, Volume: 154, Issue:2

    Topics: Adult; Choline; Creatine; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Neuralgia; Pain Management; Pain Measurement; Predictive Value of Tests; Prognosis; Reproducibility of Results; Severity of Illness Index; Spinal Cord Injuries

2013
Coherent sympathetic nerve activity in different postganglionic nerves after spinal cord transection in the cat.
    Autonomic neuroscience : basic & clinical, 2002, Jun-28, Volume: 98, Issue:1-2

    Topics: Animals; Cats; Decerebrate State; Electrophysiology; Glutamic Acid; Heart Conduction System; Kidney; Nerve Net; Spinal Cord Injuries; Spinal Nerves; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System

2002
Quantitative measurement of glutamate receptor subunit protein expression in the postnatal rat spinal cord.
    Brain research. Developmental brain research, 2002, Aug-30, Volume: 137, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Down-Regulation; Glutamic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Up-Regulation

2002
NBQX treatment improves mitochondrial function and reduces oxidative events after spinal cord injury.
    Journal of neurotrauma, 2002, Volume: 19, Issue:8

    Topics: Animals; Dizocilpine Maleate; Female; Glucose; Glutamic Acid; Injections, Spinal; Lipid Peroxidation; Mitochondria; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Synaptosomes; Thiobarbituric Acid Reactive Substances; Thoracic Vertebrae

2002
Chemical activation of C(1)-C(2) spinal neurons modulates activity of thoracic respiratory interneurons in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:4

    Topics: Animals; Cervical Vertebrae; Electric Stimulation; Electrophysiology; Glutamic Acid; Interneurons; Male; Rats; Rats, Sprague-Dawley; Respiratory System; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae

2002
A new antioxidant compound H-290/51 modulates glutamate and GABA immunoreactivity in the rat spinal cord following trauma.
    Amino acids, 2002, Volume: 23, Issue:1-3

    Topics: Animals; Antioxidants; Blood-Brain Barrier; Edema; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neuroprotective Agents; Permeability; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2002
Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production.
    The European journal of neuroscience, 2003, Volume: 17, Issue:7

    Topics: Aminoquinolines; Animals; Benzamides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluorescein; Fluorescence; Fluorescent Dyes; Functional Laterality; Glutamic Acid; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Knockout; NADPH Dehydrogenase; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nociceptin; Opioid Peptides; Peptide Fragments; Reaction Time; Spinal Cord; Spinal Cord Injuries; Time Factors

2003
Inhibitory effect of intrathecal glycine on the micturition reflex in normal and spinal cord injury rats.
    Experimental neurology, 2003, Volume: 183, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Female; Glutamic Acid; Glycine; Glycine Agents; Injections, Spinal; Lumbosacral Region; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Reflex; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Strychnine; Urinary Bladder; Urination

2003
Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing.
    Journal of neuroscience research, 2003, Oct-15, Volume: 74, Issue:2

    Topics: Animals; Astrocytes; Blood Vessels; Blood-Brain Barrier; Excitatory Amino Acid Transporter 2; Gliosis; Glutamic Acid; Luciferases; Macrophages; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Spinal Cord; Spinal Cord Injuries; Wound Healing

2003
Spinal axonal injury transiently elevates the level of metabotropic glutamate receptor 5, but not 1, in cord-projection central neurons.
    Journal of neurotrauma, 2004, Volume: 21, Issue:4

    Topics: Animals; Axons; Disease Models, Animal; Efferent Pathways; Female; Glutamic Acid; Immunohistochemistry; Neurotoxins; Rats; Rats, Wistar; Reaction Time; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Red Nucleus; Retrograde Degeneration; Spinal Cord Injuries; Synaptic Transmission; Up-Regulation

2004
Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord.
    Experimental neurology, 2004, Volume: 187, Issue:2

    Topics: Animals; Cell Count; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries; Time Factors

2004
Descending modulation of thoracic visceroreceptive transmission by C1-C2 spinal neurons.
    Autonomic neuroscience : basic & clinical, 2004, Jul-30, Volume: 114, Issue:1-2

    Topics: Action Potentials; Afferent Pathways; Animals; Bradykinin; Cervical Vertebrae; Drug Interactions; Esophagus; Glutamic Acid; Male; Neural Inhibition; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2004
Dietary glycine inhibits bladder activity in normal rats and rats with spinal cord injury.
    The Journal of urology, 2005, Volume: 173, Issue:1

    Topics: Animals; Blood-Brain Barrier; Body Weight; Female; Glutamic Acid; Glycine; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Reflex; Spinal Cord; Spinal Cord Injuries; Urinary Bladder; Urine

2005
The effect of glutamate receptor blockers on glutamate release following spinal cord injury. Lack of evidence for an ongoing feedback cascade of damage --> glutamate release --> damage --> glutamate release --> etc.
    Brain research, 2005, Mar-15, Volume: 1038, Issue:1

    Topics: Animals; Excitatory Amino Acid Antagonists; Feedback, Physiological; Glutamic Acid; Male; Neurons; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Single-Blind Method; Sodium Channel Blockers; Spinal Cord; Spinal Cord Injuries

2005
Administration of glutamate into the spinal cord at extracellular concentrations reached post-injury causes functional impairments.
    Neuroscience letters, 2005, Aug-26, Volume: 384, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Extracellular Fluid; Gait Disorders, Neurologic; Glutamic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2005
Disruption of left-right reciprocal coupling in the spinal cord of larval lamprey abolishes brain-initiated locomotor activity.
    Journal of neurophysiology, 2005, Volume: 94, Issue:3

    Topics: Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Brain; Electromyography; Escape Reaction; Evoked Potentials, Motor; Functional Laterality; Glutamic Acid; In Vitro Techniques; Interneurons; Larva; Motor Activity; Muscles; Neural Inhibition; Periodicity; Petromyzon; Physical Stimulation; Psychomotor Performance; Pyramidal Tracts; Spinal Cord; Spinal Cord Injuries

2005
Experimental spinal cord injury induced an increase of extracellular ascorbic acid concentration in anesthetized rats: a microdialysis study.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 362, Issue:1-2

    Topics: Anesthesia; Animals; Ascorbic Acid; Extracellular Space; Glutamic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2005
Spinal cord injury treatment by induction of a shift from cholinergic to glutamatergic innervation of muscle fibers.
    Muscle & nerve, 2007, Volume: 35, Issue:1

    Topics: Acetylcholine; Animals; Efferent Pathways; Glutamic Acid; Humans; Muscle, Skeletal; Nerve Regeneration; Neuromuscular Junction; Peripheral Nerves; Phenotype; Spinal Cord Injuries; Tissue Transplantation

2007
VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat.
    Experimental neurology, 2007, Volume: 204, Issue:1

    Topics: Animals; Behavior, Animal; Disease Progression; Female; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Immunohistochemistry; Microscopy, Confocal; Motor Neurons; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Sacrococcygeal Region; Spinal Cord Injuries; Tail; Vesicular Glutamate Transport Protein 1

2007
Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats.
    Neurochemical research, 2007, Volume: 32, Issue:1

    Topics: Animals; Aspartic Acid; Citrulline; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Rats; Rats, Wistar; Spinal Cord Injuries; Taurine

2007
The tripartite synapse: roles for gliotransmission in health and disease.
    Trends in molecular medicine, 2007, Volume: 13, Issue:2

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium Signaling; Epilepsy; Glutamic Acid; Humans; Models, Neurological; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Spinal Cord Injuries; Synapses; Synaptic Transmission

2007
Spinal glutamatergic NMDA-dependent pelvic nerve-to-external urethra sphincter reflex potentiation caused by a mechanical stimulation in anesthetized rats.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:6

    Topics: Action Potentials; Anesthesia; Animals; Dilatation; Electromyography; Female; GABA Agonists; GABA Antagonists; Glutamic Acid; Injections, Spinal; Muscle, Skeletal; Pelvis; Peripheral Nerves; Physical Stimulation; Pressure; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord Injuries; Urethra

2007
Serum albumin improves recovery from spinal cord injury.
    Journal of neuroscience research, 2007, May-15, Volume: 85, Issue:7

    Topics: Animals; Cells, Cultured; Glutamic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Recovery of Function; Serum Albumin; Spinal Cord Injuries

2007
Glutamine concentration and immune response of spinal cord-injured rats.
    The journal of spinal cord medicine, 2007, Volume: 30, Issue:2

    Topics: Animals; Bacterial Infections; Biomarkers; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Lymphocyte Activation; Macrophages; Male; Metabolism; Muscle, Skeletal; Muscular Atrophy; Paralysis; Peptide Hydrolases; Predictive Value of Tests; Rats; Rats, Wistar; Sepsis; Spinal Cord Injuries; T-Lymphocytes

2007
Role of endothelins as mediators of injury-induced alterations of glial glutamate turnover.
    Journal of neuroscience research, 2008, Feb-15, Volume: 86, Issue:3

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Brain; Brain Injuries; Bucladesine; Cells, Cultured; Cerebral Cortex; Endothelins; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glutamate-Ammonia Ligase; Glutamic Acid; In Vitro Techniques; Neuroglia; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2008
The neuroprotective potential of phase II enzyme inducer on motor neuron survival in traumatic spinal cord injury in vitro.
    Cellular and molecular neurobiology, 2008, Volume: 28, Issue:5

    Topics: Animals; Animals, Newborn; Cell Survival; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Glutamic Acid; Heme Oxygenase (Decyclizing); Hydroquinones; Mitochondria; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; NF-E2-Related Factor 2; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Sulfhydryl Compounds; Thiones

2008
The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis.
    Journal of neurochemistry, 2008, Volume: 105, Issue:4

    Topics: Acute Disease; Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport, Active; Cell Survival; Cytokines; Encephalitis, Viral; Glutamic Acid; Inflammation Mediators; Interleukin-1beta; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Neurons; Spinal Cord Injuries

2008
Metabolic changes in the thalamus after spinal cord injury followed by proton MR spectroscopy.
    Magnetic resonance in medicine, 2008, Volume: 59, Issue:3

    Topics: Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Glutamic Acid; Hindlimb; Hot Temperature; Inositol; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Wistar; Spinal Cord Injuries; Thalamus

2008
Pregabalin as a neuroprotector after spinal cord injury in rats.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2008, Volume: 17, Issue:6

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Apoptosis; gamma-Aminobutyric Acid; Glutamic Acid; Inflammation; Male; Methylprednisolone; Microglia; Minocycline; Models, Animal; Pregabalin; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

2008
Time-dependent effects of dexamethasone on glutamate binding, ornithine decarboxylase activity and polyamine levels in the transected spinal cord.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:1

    Topics: Animals; Dexamethasone; Glucocorticoids; Glutamic Acid; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Time Factors

1995
A functional in vitro model for studying the cellular and molecular basis of spinal cord injury.
    Spine, 1993, Volume: 18, Issue:9

    Topics: Animals; Animals, Newborn; Brain Stem; Cell Death; Glutamates; Glutamic Acid; Hindlimb; Locomotion; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries

1993
Ultrastructural quantitative analysis of glutamatergic and GABAergic synaptic terminals in the phrenic nucleus after spinal cord injury.
    The Journal of comparative neurology, 1996, Aug-26, Volume: 372, Issue:3

    Topics: Animals; Female; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Microscopy, Electron; Motor Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

1996
The role of excitatory amino acids in hypothermic injury to mammalian spinal cord neurons.
    Journal of neurotrauma, 1996, Volume: 13, Issue:12

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cell Death; Cells, Cultured; Cold Temperature; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Mice; Neurons; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord; Spinal Cord Injuries

1996
4-hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake.
    Journal of neurochemistry, 1997, Volume: 68, Issue:6

    Topics: Aldehydes; Amino Acid Transport System X-AG; Animals; Antibody Specificity; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Western; Cell Death; Cross-Linking Reagents; Female; Free Radicals; Glutamic Acid; Immunohistochemistry; Lipid Peroxidation; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Spinal Cord Injuries; Wounds and Injuries

1997
Glutamate- and GABA-immunoreactive synapses on sympathetic preganglionic neurons caudal to a spinal cord transection in rats.
    Neuroscience, 1997, Volume: 80, Issue:4

    Topics: Adrenal Medulla; Animals; Axonal Transport; Dendrites; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Glutamic Acid; Male; Microscopy, Immunoelectron; Neurons; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Synapses

1997
The hydroxyl radical scavenger Nicaraven inhibits glutamate release after spinal injury in rats.
    Neuroreport, 1998, May-11, Volume: 9, Issue:7

    Topics: Animals; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Hypothermia, Induced; Male; Niacinamide; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord; Spinal Cord Injuries; Time Factors

1998
Considerations in the determination by microdialysis of resting extracellular amino acid concentrations and release upon spinal cord injury.
    Neuroscience, 1998, Volume: 86, Issue:3

    Topics: Amino Acids; Animals; Blood-Brain Barrier; Evans Blue; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Fibers; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

1998
Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-15, Volume: 19, Issue:14

    Topics: Action Potentials; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Axons; Carrier Proteins; Cell Hypoxia; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Male; Myelin Sheath; Patch-Clamp Techniques; Pressure; Rats; Rats, Long-Evans; Receptors, AMPA; Sodium; Spinal Cord; Spinal Cord Injuries; Stress, Mechanical; Symporters

1999
Neurotoxicity of glutamate at the concentration released upon spinal cord injury.
    Neuroscience, 1999, Volume: 93, Issue:4

    Topics: Animals; Aspartic Acid; Contusions; Glutamic Acid; Male; Microdialysis; Nerve Degeneration; Neurotoxins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries

1999
Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord.
    Experimental neurology, 1999, Volume: 159, Issue:2

    Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Citrulline; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine; Time Factors

1999
Chronic and acute compressive spinal cord lesions in dogs due to intervertebral disc herniation are associated with elevation in lumbar cerebrospinal fluid glutamate concentration.
    Journal of neurotrauma, 1999, Volume: 16, Issue:12

    Topics: Acute Disease; Animals; Chronic Disease; Dogs; Glutamic Acid; Intervertebral Disc Displacement; Lumbar Vertebrae; Lumbosacral Region; Osmolar Concentration; Reference Values; Spinal Cord Injuries; Thoracic Vertebrae

1999
Adenosine release upon spinal cord injury.
    Brain research, 2000, Jan-31, Volume: 854, Issue:1-2

    Topics: Adenosine; Animals; Glutamic Acid; Microdialysis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Theophylline

2000
Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord.
    Brain research, 2000, May-26, Volume: 865, Issue:2

    Topics: Animals; Glutamic Acid; Kainic Acid; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2000
Riluzole improves measures of oxidative stress following traumatic spinal cord injury.
    Brain research, 2000, Jul-07, Volume: 870, Issue:1-2

    Topics: Animals; Female; Glutamic Acid; Mitochondria; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Long-Evans; Rhodamines; Riluzole; Spinal Cord Injuries; Synaptosomes; Thiobarbituric Acid Reactive Substances

2000
Ultrastructural evidence for a preferential elimination of glutamate-immunoreactive synaptic terminals from spinal motoneurons after intramedullary axotomy.
    The Journal of comparative neurology, 2000, Sep-11, Volume: 425, Issue:1

    Topics: Animals; Axotomy; Cats; Dendrites; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Microscopy, Electron; Microtomy; Motor Neurons; Nerve Regeneration; Neuronal Plasticity; Neurotoxins; Presynaptic Terminals; Spinal Cord; Spinal Cord Injuries

2000
Riluzole and methylprednisolone combined treatment improves functional recovery in traumatic spinal cord injury.
    Journal of neurotrauma, 2000, Volume: 17, Issue:9

    Topics: Animals; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Gait Disorders, Neurologic; Glucocorticoids; Glutamic Acid; Locomotion; Methylprednisolone; Myelin Sheath; Rats; Rats, Long-Evans; Recovery of Function; Riluzole; Spinal Cord; Spinal Cord Injuries

2000
Stroke.
    Neurobiology of disease, 2000, Volume: 7, Issue:5

    Topics: Animals; Apoptosis; Cycloheximide; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Intracranial Embolism; Necrosis; Neuroprotective Agents; Plasminogen Activators; Spinal Cord Injuries; Stroke; Tissue Plasminogen Activator

2000
AIDA reduces glutamate release and attenuates mechanical allodynia after spinal cord injury.
    Neuroreport, 2000, Sep-28, Volume: 11, Issue:14

    Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperalgesia; Indans; Male; Mechanoreceptors; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord Injuries

2000
Neuronal survival after CNS insult is determined by a genetically encoded autoimmune response.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jul-01, Volume: 21, Issue:13

    Topics: Animals; Autoimmunity; Cell Count; Cell Survival; Central Nervous System; Disease Models, Animal; Drug Administration Routes; Encephalomyelitis, Autoimmune, Experimental; Female; Genetic Predisposition to Disease; Glutamic Acid; Immunity, Cellular; Injections; Male; Mice; Mice, Inbred Strains; Mice, Nude; Nerve Crush; Neurons; Optic Nerve Injuries; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Retinal Ganglion Cells; Species Specificity; Spinal Cord Injuries; T-Lymphocytes; Wounds, Nonpenetrating

2001
Tumor necrosis factor-alpha induces cFOS and strongly potentiates glutamate-mediated cell death in the rat spinal cord.
    Neurobiology of disease, 2001, Volume: 8, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Death; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Microglia; Neurons; Neurotoxins; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2001
The addition of epinephrine to tetracaine injected intrathecally sustains an increase in glutamate concentrations in the cerebrospinal fluid and worsens neuronal injury.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:4

    Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Epinephrine; Glutamic Acid; Hemodynamics; Injections, Spinal; Microdialysis; Neurons; Rabbits; Spinal Cord Injuries; Tetracaine; Vasoconstrictor Agents

2001
Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat.
    Journal of neurochemistry, 2001, Volume: 79, Issue:4

    Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Cord Injuries

2001
Rapid changes in expression of glutamate transporters after spinal cord injury.
    Brain research, 2002, Feb-08, Volume: 927, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Blotting, Western; Carrier Proteins; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Homeostasis; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Symporters

2002
Neurogenic bladder model for spinal cord injury: spinal cord microdialysis and chronic urodynamics.
    Brain research. Brain research protocols, 2002, Volume: 9, Issue:1

    Topics: Animals; Catheters, Indwelling; Disease Models, Animal; Female; Glutamic Acid; Glycine; Microdialysis; Neurochemistry; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Urinary Bladder; Urinary Bladder, Neurogenic

2002
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
    Journal of neurochemistry, 1989, Volume: 52, Issue:5

    Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine

1989