glutamic acid and Hypoxia-Ischemia, Brain

glutamic acid has been researched along with Hypoxia-Ischemia, Brain in 111 studies

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (1.80)18.2507
2000's80 (72.07)29.6817
2010's27 (24.32)24.3611
2020's2 (1.80)2.80

Authors

AuthorsStudies
Datta, I; Jain, NK; Sowmithra, S1
Hwang, K; Jang, JH; Jung, K; Kim, IS; Kim, M; Ko, Y; Park, KI; Shin, JE1
Aida, N; Morisaki, N; Nishi, Y; Shibasaki, J; Tomiyasu, M; Toyoshima, K1
Jiao, S; Li, Y; Liu, B; Yang, Y; Zhang, J; Zhang, X; Zhao, Y1
Chung, SH; Deng, W; Guo, F; Jiang, P; Pleasure, DE1
Jain, MR; Levison, SW; Li, H; Simonishvili, S; Wood, TL1
Barres, BA; Sloan, SA1
Beppu, K; Fukazawa, Y; Matsui, K; Sasaki, T; Shigemoto, R; Tanaka, KF; Yamanaka, A1
Alzweiri, M; Bardaweel, SK; Ishaqat, AA1
Campos, F; Castillo, J; Couce, ML; da Silva-Candal, A; Fraga, JM; Iglesias-Deus, A; Pérez-Mato, M; Rujido, S; Sobrino, T1
Johnston, MV1
Huang, L; Huang, Y; Jiang, H; Li, F; Li, H; Li, L; Li, X; Xiao, J; Yang, L; Yang, T1
Jiang, Y; Liu, X; Ma, M; Wang, L; Wen, Z; Wu, L; Xiao, L; Xie, Y; Xu, L; Yang, L; Ye, R; Zhu, W1
Burd, I; Johnston, MV; Kannan, G; Welling, J1
Le Roux, PD; Monnerie, H1
Chen, J; Guan, QH; Han, D; Hou, XY; Jiang, HX; Li, C; Liu, XM; Pei, DS; Wang, XT; Wen, XR; Zhang, GY1
Andresen, JH; Saugstad, OD1
Bruno, AN; Chagastelles, P; Frozza, RL; Gerhardt, D; Grudzinski, PB; Hoppe, JB; Horn, AP; Lenz, G; Nardi, NB; Salbego, C1
Baudry, M; Bi, X; Cheung, S; Galeano, J; Liao, G; Nguyen, N; Zhou, M1
Chang, L; Qi, J; Wang, C; Yin, P; Zhong, W; Zhu, W1
Bohn, L; de Almeida, LM; Degerone, D; Gonçalves, CA; Gottfried, C; Leite, MC; Nardin, P; Netto, CA; Pimentel, A; Rodrigues, L; Scornavaca, F; Souza, DO; Swarowsky, A; Vicente, E1
Iriyama, T; Kamei, Y; Kozuma, S; Taketani, Y1
Aragão, Mde F; Law, M; Naidich, T; Netto, JP; Valença, MM1
Drew, KL; Green, TK; Kirschner, DL; Wilson, AL1
Lin, N; Liu, C; Qiu, Y; Wu, B1
Domin, H; Jantas, D; Kajta, M; Kutner, A; Lasoń, W; Makarewicz, D; Ziemińska, E; Łazarewicz, JW1
Björkman, ST; Colditz, PB; Miller, SM; Pow, DV; Sullivan, SM1
Buriticá, E; Escobar, MI; García-Cairasco, N; Guzmán, F; Pimienta, HJ; Villamil, L1
Bette, S; Engele, J; Lehmann, C1
Dos-Anjos, S; Fernández-López, A; Martínez-Villayandre, B; Montori, S; Pérez-García, CC1
Castillo, A; Fernández-Ruiz, J; Martinez-Orgado, J; Romero, J; Tolón, MR1
Chen, H; Jiang, Y; Li, C; Li, H; Yan, Z; Yang, J; Zhang, Z1
Dabrowski, M; Gozdz, A; Kaminska, B; Szydlowska, K; Zawadzka, M1
Mao, M; Qu, Y; Zeng, W1
Chae, SJ; Choi, S; Choi, SK; Kang, SW; Lee, GJ; Park, E; Park, HK1
Chen, YR; Duan, SM; Jiang, ZL; Shi, JS; Zhou, C1
Kofke, WA; Larach, DB; Le Roux, P1
Jensen, FE; Kinney, HC; Rosenberg, PA; Volpe, JJ1
Holopainen, IE; Laurén, HB1
Crawford, DC; Hogins, J; Jiang, X; Mennerick, S1
Chiu, TH; Huang, YT; Lai, CJ; Lai, PC; Wang, PJ; Wu, CC1
Fu, XH; Guo, QY; Wang, HW; Wang, XM; Wang, XY; Wu, XY; Zhang, WQ1
Nuñez, J1
Borisova, T; Kasatkina, L; Krisanova, N; Sivko, R1
Degos, V; Gressens, P; Heijnen, CJ; Kavelaars, A; Nijboer, CH; Willemen, HL1
Brambrink, AM; Guerguerian, AM; Huganir, RL; Martin, LJ; Traystman, RJ1
Hori, O; Kitao, Y; Matsushita, K; Matsuyama, T; Miyazaki, M; Ogawa, S; Ozawa, K1
Biancari, F; Hirvonen, J; Juvonen, T; Kiviluoma, K; Mennander, A; Pokela, M; Rimpiläinen, J; Romsi, P; Rönkä, E; Vainionpää, V1
Banczerowski-Pelyhe, I; Gulyás-Kovács, A; Takács, J; Tarnawa, I; Világi, I1
Kvrivishvili, G1
Goto, W; Hara, H; Kawazu, K; Miyawaki, N; Morikawa, N; Ota, T; Otori, Y; Tano, Y1
Frizzo, ME; Lara, DR; Prokopiuk, Ade S; Salbego, CG; Souza, DO; Vargas, CR; Wajner, M1
Liang, WL; Wu, XR; Xiong, H1
Ferriero, DM; Hamrick, SE1
Avshalumov, MV; MacGregor, DG; Rice, ME1
Lutz, PL; Milton, SL; Prentice, HM1
Ceña, V; González-García, C; Sáez-Valero, J1
Dikranian, K; Olney, JW; Tenkova, T; Young, C1
Egashira, N; Fujii, H; Fujiwara, M; Irie, K; Ishibashi, D; Iwasaki, K; Kaneko, T; Kosuna, K; Mishima, K; Pu, F; Uchida, T1
Blue, ME; Buitrago, MM; Hanley, DF; Luft, AR; Thakor, NV1
Hagberg, H; Vannucci, SJ1
Hewett, SJ; Vidwans, AS1
Bösel, J; Dirnagl, U; Djoufack, PC; Endres, M; Fink, KB; Gandor, F; Harms, C; Harms, U; Hörtnagl, H; Megow, D; Synowitz, M1
Abulrob, A; Brunette, E; Faid, K; Mealing, G; Stanimirovic, D; Tauskela, JS1
Bonet, B; Casanova, I; Fernández-López, D; Leza, JC; Lizasoain, I; Lorenzo, P; Martínez-Orgado, J; Moro, MA1
Arteni, NS; Lavinsky, D; Moretto, MB; Netto, CA; Rocha, JB; Souza, DO; Wofchuk, S1
Bates, TE; Calver, AA; Colombo, S; Rosin, C; Skaper, SD1
Ibara, S; Kato, E; Kobayashi, K; Kusumoto, M; Maruyama, H; Maruyama, Y1
Emin Buyukokuroglu, M; Gepdiremen, A; Halici, Z; Ors, R; Tastekin, A1
Chace, DH; Kohli, R; Wainwright, MS; Whitington, PF1
Bainy, AC; Brongholi, K; Dafre, AL; Souza, DG; Tasca, CI1
Chen, Z; Ge, QF; Hu, X; Huang, XJ; Luo, JH; Ma, ZQ; Song, Y; Wei, EQ; Zhang, L; Zhang, WP1
Azimi-Zonooz, A; Connor, JA; Shuttleworth, CW1
Kuroiwa, T; Makita, K; Tanaka, K; Yamashita, A1
Fischer, I; Himes, BT; Park, KI; Snyder, EY; Stieg, PE; Tessler, A1
Allcock, N; Back, SA; Craig, A; Fern, R; Kayton, RJ; Luo, NL; Meshul, CK1
Homola, A; Kuhlen, R; Slais, K; Syková, E; Zoremba, N1
Back, SA1
Blondeau, N; Guo, Z; Jiang, X; Lipsky, RH; Marini, AM; Mattson, MP; Novelli, A; Pan, H; Wu, X1
Goldberg, MP; Underhill, SM1
Billiards, SS; Folkerth, RD; Haynes, RL; Kinney, HC; Pierson, CR1
Bambrick, L; Hilton, GD; McCarthy, MM; Nunez, JL; Thompson, SM1
de Brum-Fernandes, AJ; Doré, S; Maruyama, T; Narumiya, S; Saleem, S; Zhuang, H1
Brorson, JR; Li, D; Shao, Z; Vanden Hoek, TL1
Altieri, S; Brywe, KG; Gangoli, N; Hagberg, H; Levison, SW; Loladze, V; Mallard, C; Wood, TL1
Wu, EX; Yang, J1
Battú, CE; Boff, B; Godinho, G; Gottfried, C; Pires, TD; Salbego, C; Souza, DO; Thomazi, AP; Wofchuk, ST1
Amaniti, E; Kouvelas, D; Lallas, A; Papazisis, G; Pourzitaki, C; Sardeli, C1
Groenendaal, F; Heijnen, CJ; Kavelaars, A; Nijboer, CH; van Bel, F; Vroon, A1
Aral, YZ; Atalay, Y; Biberoglu, G; Gücüyener, K; Hasanoğlu, A; Türkyilmaz, C1
Deulofeu, R; Figueras-Aloy, J; Jiménez, R; Roldán, A1
Asai, S; Ishikawa, K; Kohno, T; Nagata, T; Takahashi, Y; Zhao, H1
Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L1
Asai, S; Ishii, Y; Ishikawa, K; Kohno, T; Kunimatsu, T; Nagata, T; Takahashi, Y; Zhao, H1
Berlanga, J; Fando, JL; Manso-Tomico, J; Martín, ME; Muñoz, F; Salinas, M1
Li, WE; Nagy, JI1
Follett, PL; Jensen, FE; Rosenberg, PA; Volpe, JJ1
Jaako, K; Kaasik, A; Kalda, A; Zharkovsky, A1
Dawson, DA; Palmer, AM; Wadsworth, G1
Brucklacher, RM; Vannucci, RC; Vannucci, SJ1
de Vries, LS; Groenendaal, F; Roelants-Van Rijn, AM; Toet, MC; van Der Grond, J1
Anttila, V; Heinonen, H; Hirvonen, J; Jäntti, V; Juvonen, T; Kiviluoma, K; Ohtonen, P; Pokela, M; Rimpiläinen, J; Vainionpää, V1
Gratzl, O; Langemann, H; Mendelowitsch, A; Ritz, MF; Ros, J1
Gozal, D; Gozal, E; Payne, RS; Schurr, A; Tseng, MT1
Andersson, K; Chen, Y; Dell'Anna, E; Engidawork, E; Goiny, M; Gross, J; Herrera-Marschitz, M; Kohlhauser, C; Loidl, F; Lubec, B; Lubec, G; Stoeckler, S1
Ishida, A; Johnston, MV; Lange, MS; Trescher, WH1
Fukamachi, S; Furuta, A; Ikeda, T; Ikenoue, T; Iwaki, T; Kaneoka, T; Rothstein, JD1
Ikeda, K; Nara, Y; Tagami, M; Tsumagari, S; Yamagata, K; Yamori, Y1
Attwell, D; Hamann, M; Marie, H; Rossi, DJ1
Matsumoto, M; Nakamura, K; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M1
Armstead, WM1

Reviews

14 review(s) available for glutamic acid and Hypoxia-Ischemia, Brain

ArticleYear
D-Serine in neurobiology: CNS neurotransmission and neuromodulation.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:2

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Central Nervous System; Epilepsy; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Mental Disorders; Neurodegenerative Diseases; Neuronal Plasticity; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission

2014
Excitotoxicity as a Common Mechanism for Fetal Neuronal Injury with Hypoxia and Intrauterine Inflammation.
    Advances in pharmacology (San Diego, Calif.), 2016, Volume: 76

    Topics: Animals; Brain Injuries; Female; Glutamic Acid; Humans; Hypoxia; Hypoxia-Ischemia, Brain; Inflammation; Pregnancy

2016
[The effects of hypoxic-ischemia on glutamate transporters].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2010, Volume: 27, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Synapses; Synaptic Transmission

2010
The developing oligodendrocyte: key cellular target in brain injury in the premature infant.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2011, Volume: 29, Issue:4

    Topics: Animals; Brain Injuries; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunity, Innate; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Leukomalacia, Periventricular; Microglia; Oligodendroglia; Reactive Oxygen Species

2011
Glutamate signaling in the pathophysiology and therapy of prenatal insults.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 100, Issue:4

    Topics: Asphyxia; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Receptors, Glutamate; Signal Transduction; Survival Rate

2012
Sex and steroid hormones in early brain injury.
    Reviews in endocrine & metabolic disorders, 2012, Volume: 13, Issue:3

    Topics: Animals; Brain; Brain Injuries; Estradiol; Female; Glutamic Acid; Gonadal Steroid Hormones; Hippocampus; Humans; Hypoxia-Ischemia, Brain; Male; Models, Animal; Neuroprotective Agents; Receptors, GABA-A; Sex Characteristics; Testosterone

2012
Glycine and neuroprotective effect of hypothermia in hypoxic-ischemic brain damage.
    Neuroreport, 2002, Nov-15, Volume: 13, Issue:16

    Topics: Animals; Glutamic Acid; Glycine; Humans; Hypothermia; Hypoxia-Ischemia, Brain

2002
[Pathophysiological alterations in cultured astrocytes exposed to hypoxia/reoxygenation].
    Sheng li ke xue jin zhan [Progress in physiology], 2000, Volume: 31, Issue:3

    Topics: Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Nitric Oxide; Receptors, N-Methyl-D-Aspartate

2000
The injury response in the term newborn brain: can we neuroprotect?
    Current opinion in neurology, 2003, Volume: 16, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Fetal Diseases; Glutamic Acid; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, Newborn, Diseases; Inflammation; Neuroprotective Agents; Oxidative Stress; Receptors, N-Methyl-D-Aspartate

2003
Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia.
    Current molecular medicine, 2004, Volume: 4, Issue:2

    Topics: Animals; Animals, Newborn; Apoptosis; Brain; Cell Death; Central Nervous System; Glutamic Acid; Hypoxia; Hypoxia-Ischemia, Brain; Immunohistochemistry; Ischemia; Microscopy, Electron; Nerve Degeneration; Neurons; Rats; Silver Staining; Synapses; Time Factors

2004
Hypoxia-ischemia in the immature brain.
    The Journal of experimental biology, 2004, Volume: 207, Issue:Pt 18

    Topics: Apoptosis; Brain; Child; Energy Metabolism; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Monosaccharide Transport Proteins; Neurotoxins; Oxidative Stress

2004
Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms.
    Mental retardation and developmental disabilities research reviews, 2006, Volume: 12, Issue:2

    Topics: Adenosine; Cytokines; Disease Progression; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Leukomalacia, Periventricular; Magnetic Resonance Imaging; Obstetric Labor Complications; Oligodendroglia; Pregnancy; Pregnancy Complications

2006
Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli.
    Amino acids, 2007, Volume: 32, Issue:3

    Topics: Adaptation, Physiological; Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium Signaling; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Learning; Memory; N-Methylaspartate; Neurons; NF-kappa B; Receptors, N-Methyl-D-Aspartate; Seizures

2007
Is the late preterm infant more vulnerable to gray matter injury than the term infant?
    Clinics in perinatology, 2006, Volume: 33, Issue:4

    Topics: Apoptosis; Brain; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Necrosis; Neurons

2006

Trials

2 trial(s) available for glutamic acid and Hypoxia-Ischemia, Brain

ArticleYear
Proton magnetic resonance spectroscopy in neonates with hypoxic-ischemic injury and its prognostic value.
    Translational research : the journal of laboratory and clinical medicine, 2008, Volume: 152, Issue:5

    Topics: Asphyxia Neonatorum; Basal Ganglia; Choline; Creatine; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Logistic Models; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Predictive Value of Tests; Prognosis; Protons; Severity of Illness Index; Thalamus

2008
Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy.
    Acta paediatrica (Oslo, Norway : 1992), 1999, Volume: 88, Issue:10

    Topics: Analysis of Variance; Aspartic Acid; Asphyxia Neonatorum; Chi-Square Distribution; Chromatography, High Pressure Liquid; Electroencephalography; Female; Glutamic Acid; Glycine; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Neurotransmitter Agents; Prognosis; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Spinal Puncture; Taurine

1999

Other Studies

95 other study(ies) available for glutamic acid and Hypoxia-Ischemia, Brain

ArticleYear
Evaluating In Vitro Neonatal Hypoxic-Ischemic Injury Using Neural Progenitors Derived from Human Embryonic Stem Cells.
    Stem cells and development, 2020, Volume: 29, Issue:14

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Biomarkers; Calcium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Glucose; Glutamic Acid; Glutathione; Human Embryonic Stem Cells; Humans; Hypoxia-Ischemia, Brain; Multidrug Resistance-Associated Proteins; Neural Stem Cells; Oxidative Stress; Oxygen; Potassium Chloride; Reactive Oxygen Species

2020
TNF-α Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury.
    Cells, 2020, 05-11, Volume: 9, Issue:5

    Topics: Animals; Baculoviral IAP Repeat-Containing 3 Protein; Behavior, Animal; Brain Injuries; Caspase 3; Cell Line; Cell Polarity; Cell Survival; Chemokine CX3CL1; Culture Media, Conditioned; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Mice, Inbred ICR; Microglia; Nerve Growth Factors; Neural Stem Cells; Neurons; Neuroprotection; Phenotype; Stress, Physiological; Tumor Necrosis Factor-alpha; Up-Regulation

2020
Changes in Brain Metabolite Concentrations after Neonatal Hypoxic-ischemic Encephalopathy.
    Radiology, 2018, Volume: 288, Issue:3

    Topics: Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Gray Matter; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Patient Outcome Assessment; Predictive Value of Tests; Retrospective Studies

2018
Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II.
    Free radical biology & medicine, 2019, 02-01, Volume: 131

    Topics: Animals; Apoptosis Inducing Factor; Astragalus propinquus; Female; Gene Expression Regulation; Glutamic Acid; Hexokinase; Humans; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Neuroprotective Agents; Oxygen Consumption; Parthanatos; Primary Cell Culture; Protein Binding; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Saponins; Triterpenes

2019
Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum.
    Cell death & disease, 2013, Mar-14, Volume: 4

    Topics: Animals; Animals, Newborn; Antigens; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Line; Cell Lineage; Cerebellum; Gene Expression Regulation, Developmental; Glutamic Acid; Hypoxia-Ischemia, Brain; Integrases; Mice; Mice, Transgenic; Myelin Proteolipid Protein; Nerve Tissue Proteins; Neural Stem Cells; Neurogenesis; Oligodendrocyte Transcription Factor 2; Oligodendroglia; Proteoglycans; Signal Transduction

2013
Identification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia-ischemia.
    ASN neuro, 2013, Dec-23, Volume: 5, Issue:5

    Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Cerebellum; Culture Media, Conditioned; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Insulin-Like Growth Factor I; Mitochondria; Neurotoxicity Syndromes; Oligodendroglia; Protein Transport; Rats; Rats, Wistar; Stem Cells; Time Factors

2013
The detrimental role of glial acidification during ischemia.
    Neuron, 2014, Jan-22, Volume: 81, Issue:2

    Topics: Acidosis; Animals; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroglia; Optogenetics

2014
Optogenetic countering of glial acidosis suppresses glial glutamate release and ischemic brain damage.
    Neuron, 2014, Jan-22, Volume: 81, Issue:2

    Topics: Acidosis; Animals; Animals, Newborn; Archaeal Proteins; Cerebellum; Channelrhodopsins; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia; Hypoxia-Ischemia, Brain; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Neuroglia; Optogenetics; Sodium Channel Blockers; Vesicular Acetylcholine Transport Proteins

2014
Potential protective role of endogenous glutamate-oxaloacetate transaminase against glutamate excitotoxicity in fetal hypoxic-ischaemic asphyxia.
    Developmental medicine and child neurology, 2016, Volume: 58, Issue:1

    Topics: Aspartate Aminotransferases; Asphyxia Neonatorum; Cross-Sectional Studies; Female; Fetal Blood; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Neuroprotection; Neurotoxins

2016
Evidence for a mechanism to lower glutamate levels in fetal hypoxia-ischemia caused by asphyxia.
    Developmental medicine and child neurology, 2016, Volume: 58, Issue:1

    Topics: Aspartate Aminotransferases; Asphyxia Neonatorum; Female; Fetal Blood; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Male

2016
TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Decline.
    Neuroscience bulletin, 2016, Volume: 32, Issue:1

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Cognition Disorders; Disease Models, Animal; Female; Glutamic Acid; Hypoxia-Ischemia, Brain; Immunoblotting; Male; Maze Learning; Myelin Sheath; Neurogenesis; Neuroprotective Agents; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley

2016
Caveolin-1 is a checkpoint regulator in hypoxia-induced astrocyte apoptosis via Ras/Raf/ERK pathway.
    American journal of physiology. Cell physiology, 2016, 06-01, Volume: 310, Issue:11

    Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Brain; Caveolin 1; Cell Hypoxia; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Phosphorylation; Primary Cell Culture; Protein Kinase Inhibitors; raf Kinases; ras Proteins; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Transfection

2016
Glutamate alteration of glutamic acid decarboxylase (GAD) in GABAergic neurons: the role of cysteine proteases.
    Experimental neurology, 2008, Volume: 213, Issue:1

    Topics: Animals; Brain Damage, Chronic; Calcium Signaling; Calpain; Cathepsins; Cells, Cultured; Cerebral Cortex; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hypoxia-Ischemia, Brain; Mice; Mice, Inbred BALB C; Neurons; Neurotoxins; Receptors, N-Methyl-D-Aspartate

2008
GluR6-containing KA receptor mediates the activation of p38 MAP kinase in rat hippocampal CA1 region during brain ischemia injury.
    Hippocampus, 2009, Volume: 19, Issue:1

    Topics: Animals; Brain Infarction; Cell Survival; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; GluK2 Kainate Receptor; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase 3; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinase Kinase 11; Oligodeoxyribonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Reperfusion Injury; Synaptic Transmission

2009
Effects of nicotine infusion on striatal glutamate and cortical non-protein-bound iron in hypoxic newborn piglets.
    Neonatology, 2008, Volume: 94, Issue:4

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Iron; Neuroprotective Agents; Nicotine; Random Allocation; Swine

2008
Conditioned medium from mesenchymal stem cells induces cell death in organotypic cultures of rat hippocampus and aggravates lesion in a model of oxygen and glucose deprivation.
    Neuroscience research, 2009, Volume: 63, Issue:1

    Topics: Animals; Cell Death; Cells, Cultured; Culture Media, Conditioned; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nerve Degeneration; Organ Culture Techniques; Propidium; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2009
Reduced early hypoxic/ischemic brain damage is associated with increased GLT-1 levels in mice expressing mutant (P301L) human tau.
    Brain research, 2009, Jan-09, Volume: 1247

    Topics: Amino Acid Sequence; Animals; Apoptosis; Brain Infarction; Calpain; Caspase 3; Cytoprotection; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Organ Culture Techniques; tau Proteins; Up-Regulation

2009
Astroglial and cognitive effects of chronic cerebral hypoperfusion in the rat.
    Brain research, 2009, Jan-28, Volume: 1251

    Topics: Animals; Astrocytes; Biomarkers; Carotid Stenosis; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Male; Maze Learning; Memory Disorders; Nerve Growth Factors; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Synaptic Transmission

2009
Bax-inhibiting peptide protects glutamate-induced cerebellar granule cell death by blocking Bax translocation.
    Neuroscience letters, 2009, Feb-13, Volume: 451, Issue:1

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspases; Cerebellum; Cytochromes c; Cytoprotection; Dose-Response Relationship, Drug; Glutamic Acid; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Indicators and Reagents; Male; Neurons; Neuroprotective Agents; Oligopeptides; Peptides; Protein Transport; Rats; Rats, Sprague-Dawley; Tetrazolium Salts

2009
Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome.
    Arquivos de neuro-psiquiatria, 2009, Volume: 67, Issue:1

    Topics: Child; Child, Preschool; Female; Glutamic Acid; Glutamine; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Near Drowning; Prognosis; Protons

2009
Simultaneous efflux of endogenous D-ser and L-glu from single acute hippocampus slices during oxygen glucose deprivation.
    Journal of neuroscience research, 2009, Volume: 87, Issue:12

    Topics: Acute Disease; Animals; Diffusion Chambers, Culture; Glucose; Glutamic Acid; Glutamine; Hippocampus; Hypoxia-Ischemia, Brain; Isomerism; Male; Neurons; Organ Culture Techniques; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Serine

2009
Neuroprotective effect of memantine combined with topiramate in hypoxic-ischemic brain injury.
    Brain research, 2009, Jul-28, Volume: 1282

    Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Brain Infarction; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Fructose; Glutamic Acid; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Male; Memantine; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Topiramate; Treatment Outcome

2009
Neuroprotection by co-treatment and post-treating with calcitriol following the ischemic and excitotoxic insult in vivo and in vitro.
    Neurochemistry international, 2009, Volume: 55, Issue:5

    Topics: Animals; Calcitriol; Caspase 3; Enzyme Activation; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Neocortex; Neuroglia; Neurons; Neuroprotective Agents; Rats

2009
Structural remodeling of gray matter astrocytes in the neonatal pig brain after hypoxia/ischemia.
    Glia, 2010, Jan-15, Volume: 58, Issue:2

    Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cell Size; D-Aspartic Acid; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Hypoxia-Ischemia, Brain; Immunohistochemistry; Isoquinolines; Male; Nerve Fibers, Unmyelinated; Swine; Time Factors

2010
Changes in calcium-binding protein expression in human cortical contusion tissue.
    Journal of neurotrauma, 2009, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Antigens, Nuclear; Biomarkers; Brain Injuries; Calbindin 2; Calbindins; Calcium-Binding Proteins; Cerebral Cortex; Disease Progression; Female; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunohistochemistry; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Tissue Proteins; Neurons; Parvalbumins; S100 Calcium Binding Protein G; Young Adult

2009
High extracellular glutamate modulates expression of glutamate transporters and glutamine synthetase in cultured astrocytes.
    Brain research, 2009, Nov-10, Volume: 1297

    Topics: Animals; Animals, Newborn; Astrocytes; Brain; Brain Chemistry; Cell Death; Cells, Cultured; Down-Regulation; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glutamate-Ammonia Ligase; Glutamic Acid; Hypoxia-Ischemia, Brain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate

2009
Early modifications in N-methyl-D-aspartate receptor subunit mRNA levels in an oxygen and glucose deprivation model using rat hippocampal brain slices.
    Neuroscience, 2009, Dec-15, Volume: 164, Issue:3

    Topics: Animals; Down-Regulation; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Models, Neurological; Organ Culture Techniques; Protein Subunits; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Synaptic Transmission; Time Factors; Up-Regulation

2009
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors.
    Neurobiology of disease, 2010, Volume: 37, Issue:2

    Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Animals, Newborn; Apoptosis; Brain; Cannabidiol; Caspase Inhibitors; Caspases; Cytoprotection; Disease Models, Animal; Down-Regulation; Glutamic Acid; Hypoxia-Ischemia, Brain; Inflammation Mediators; Interleukin-6; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Organ Culture Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Purinergic P1

2010
Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats.
    Neurochemistry international, 2010, Volume: 56, Issue:3

    Topics: Animals; Antioxidants; Brain; Brain Infarction; Disease Models, Animal; Ethanolamines; Excitatory Postsynaptic Potentials; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypothalamus; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Inhibitory Postsynaptic Potentials; Male; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Treatment Outcome

2010
Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506.
    Journal of neurochemistry, 2010, Volume: 113, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Apoptosis; Astrocytes; Butadienes; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Hypoxia-Ischemia, Brain; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Nitriles; Rats; Rats, Wistar; Tacrolimus

2010
Correlation between extracellular glutamate release and neuronal cell death in an eleven vessel occlusion model in rat.
    Brain research, 2010, Jun-25, Volume: 1342

    Topics: Animals; Apoptosis; Brain; Cerebrovascular Circulation; Disease Models, Animal; Extracellular Fluid; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley

2010
[Glutamate-related mechanism of ginsenosides against anoxic-ischemic brain damage].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2001, Volume: 17, Issue:2

    Topics: Animals; Astrocytes; Cells, Cultured; Ginsenosides; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2001
Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature.
    Neurocritical care, 2011, Volume: 15, Issue:3

    Topics: Aerobiosis; Anaerobiosis; Blood Glucose; Brain; Brain Injuries; Critical Care; Energy Metabolism; Extracellular Fluid; Glutamic Acid; Glycerol; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Microdialysis; Monitoring, Physiologic; Oxidation-Reduction; Oxygen; Pyruvic Acid; Regional Blood Flow

2011
Presynaptic silencing is an endogenous neuroprotectant during excitotoxic insults.
    Neurobiology of disease, 2011, Volume: 43, Issue:2

    Topics: Animals; Animals, Newborn; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Male; Neural Inhibition; Neurotoxins; Presynaptic Terminals; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Synaptic Transmission

2011
Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats.
    Journal of biomedical science, 2011, Sep-21, Volume: 18

    Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Western; Ceftriaxone; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Neuropsychological Tests; Rats

2011
Expression of N-methyl-d-aspartate receptor 1 and its phosphorylated state in basal ganglia of a neonatal piglet hypoxic-ischemic brain injury model: a controlled study of (1)H MRS.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:5

    Topics: Animals; Animals, Newborn; Basal Ganglia; Glutamic Acid; Glutamine; Hypoxia-Ischemia, Brain; Magnetic Resonance Spectroscopy; Neurons; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Swine

2012
Neuroprotection by lowering cholesterol: a decrease in membrane cholesterol content reduces transporter-mediated glutamate release from brain nerve terminals.
    Biochimica et biophysica acta, 2012, Volume: 1822, Issue:10

    Topics: Amino Acid Transport System X-AG; Animals; beta-Cyclodextrins; Brain; Brain Injuries; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Cholesterol; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Membrane Potentials; Nerve Endings; Neuroprotective Agents; Protons; Rats; Rats, Wistar; Sodium; Stroke; Synaptic Vesicles; Synaptosomes

2012
Astrocyte GRK2 as a novel regulator of glutamate transport and brain damage.
    Neurobiology of disease, 2013, Volume: 54

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cytoskeletal Proteins; Disease Models, Animal; Female; Fluorescent Antibody Technique; G-Protein-Coupled Receptor Kinase 2; Glutamic Acid; Hypoxia-Ischemia, Brain; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Small Interfering

2013
Altered expression and phosphorylation of N-methyl-D-aspartate receptors in piglet striatum after hypoxia-ischemia.
    Brain research. Molecular brain research, 2002, Jul-15, Volume: 104, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Antibody Specificity; Asphyxia Neonatorum; Corpus Striatum; Disease Models, Animal; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunoblotting; Infant, Newborn; Male; Nerve Degeneration; Neurons; Neurotoxins; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Transmission; Up-Regulation

2002
Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:8

    Topics: Adenoviridae; Animals; Arsenates; Brefeldin A; Calcium; Cathepsin B; Cell Death; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Genetic Vectors; Gerbillinae; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Hypoxia-Ischemia, Brain; In Situ Hybridization; Male; Neurons; Protein Synthesis Inhibitors; Proteins; Staurosporine; Thapsigargin

2002
Potential neuroprotective benefits of erythropoietin during experimental hypothermic circulatory arrest.
    The Journal of thoracic and cardiovascular surgery, 2002, Volume: 124, Issue:4

    Topics: Animals; Apoptosis; Brain; Electroencephalography; Erythropoietin; Female; Glutamic Acid; Heart Arrest, Induced; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Survival Rate; Swine

2002
Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats.
    Brain research bulletin, 2002, Oct-15, Volume: 59, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anti-Anxiety Agents; Asphyxia Neonatorum; Behavior, Animal; Benzodiazepines; Cell Death; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Movement Disorders; Neostriatum; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Synaptic Transmission

2002
Protective effects of timolol against the neuronal damage induced by glutamate and ischemia in the rat retina.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Action Potentials; Acute Disease; Animals; Cell Death; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Excitatory Amino Acid Antagonists; Fetus; Glaucoma; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Retinal Degeneration; Retinal Ganglion Cells; Timolol

2002
Guanosine enhances glutamate uptake in brain cortical slices at normal and excitotoxic conditions.
    Cellular and molecular neurobiology, 2002, Volume: 22, Issue:3

    Topics: Animals; Cell Death; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Glutamic Acid; Guanosine; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Synapses; Taurine

2002
Brain edema induced by in vitro ischemia: causal factors and neuroprotection.
    Journal of neurochemistry, 2003, Volume: 85, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antioxidants; Brain Edema; Cell Hypoxia; Cyclic N-Oxides; Cyclosporine; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; In Vitro Techniques; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, Glutamate; Sodium-Calcium Exchanger; Spin Labels; Water

2003
Is turtle longevity linked to enhanced mechanisms for surviving brain anoxia and reoxygenation?
    Experimental gerontology, 2003, Volume: 38, Issue:7

    Topics: Adaptation, Physiological; Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia-Ischemia, Brain; Ion Channels; Longevity; Reactive Oxygen Species; Receptors, Dopamine; Receptors, GABA-A; Turtles

2003
Acetylcholinesterase activation in organotypic rat hippocampal slice cultures deprived of oxygen and glucose.
    Neuroscience letters, 2003, Sep-11, Volume: 348, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Animals, Newborn; Cell Death; Cerebral Infarction; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Nerve Degeneration; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Up-Regulation

2003
Protective effect of buckwheat polyphenols against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia.
    Journal of pharmacological sciences, 2004, Volume: 94, Issue:4

    Topics: Animals; Fagopyrum; Flavonoids; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Male; Maze Learning; Memory; Memory Disorders; Microdialysis; Neurons; Neuroprotective Agents; Nitrates; Nitrites; Phenols; Polyphenols; Rats; Rats, Wistar; Time Factors

2004
Effects of somatosensory electrical stimulation on neuronal injury after global hypoxia-ischemia.
    Experimental brain research, 2004, Volume: 158, Issue:3

    Topics: Afferent Pathways; Animals; Caspase 3; Caspases; Cerebellum; Cerebral Infarction; Disease Models, Animal; Electric Stimulation Therapy; Evoked Potentials, Somatosensory; Extracellular Signal-Regulated MAP Kinases; Functional Laterality; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Male; Median Nerve; Nerve Degeneration; Rats; Rats, Wistar; Somatosensory Cortex

2004
Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2.
    Experimental neurology, 2004, Volume: 190, Issue:1

    Topics: Animals; Aspartic Acid; Cell Death; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Extracellular Space; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Mice; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzoates; Riluzole; Synapses; Tetanus Toxin

2004
Neuroprotective effects of atorvastatin against glutamate-induced excitotoxicity in primary cortical neurones.
    Journal of neurochemistry, 2005, Volume: 92, Issue:6

    Topics: Acyl Coenzyme A; Animals; Apoptosis; Atorvastatin; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Glucose; Glutamic Acid; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoxia-Ischemia, Brain; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; Pyrroles; Rats; Receptors, Glutamate

2005
Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-D-aspartate receptor redistribution.
    Journal of neurochemistry, 2005, Volume: 92, Issue:6

    Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Cholesterol; Cyclodextrins; Cytoprotection; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia-Ischemia, Brain; Intracellular Signaling Peptides and Proteins; Membrane Microdomains; Membrane Proteins; Methylation; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Receptor Aggregation; Receptors, N-Methyl-D-Aspartate; Sulfur Compounds; Synaptic Transmission

2005
Immature rat brain slices exposed to oxygen-glucose deprivation as an in vitro model of neonatal hypoxic-ischemic encephalopathy.
    Journal of neuroscience methods, 2005, Jun-30, Volume: 145, Issue:1-2

    Topics: Animals; Animals, Newborn; Blotting, Western; Brain; Cell Death; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; L-Lactate Dehydrogenase; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Culture Techniques; Oxygen; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2005
Hypoxic-ischemic insult decreases glutamate uptake by hippocampal slices from neonatal rats: prevention by guanosine.
    Experimental neurology, 2005, Volume: 195, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Infarction; Glutamic Acid; Guanosine; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Rats; Rats, Wistar; Time Factors

2005
Dopamine D2 and D3 receptor agonists limit oligodendrocyte injury caused by glutamate oxidative stress and oxygen/glucose deprivation.
    Glia, 2005, Volume: 52, Issue:4

    Topics: Animals; Cell Death; Cells, Cultured; Dopamine Agonists; Dopamine Antagonists; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Oligodendroglia; Oxidative Stress; Oxygen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger

2005
Changes of lactate, glucose, ionized calcium and glutamate concentrations in cephalic vein blood during brain hypothermia using extracorporeal membrane oxygenation (ECMO) in a newborn infant with hypoxic-ischemic encephalopathy.
    Journal of perinatal medicine, 2005, Volume: 33, Issue:4

    Topics: Blood Glucose; Brain; Calcium; Extracorporeal Membrane Oxygenation; Female; Glutamic Acid; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Lactic Acid; Male; Pregnancy

2005
L-carnitine protects against glutamate- and kainic acid-induced neurotoxicity in cerebellar granular cell culture of rats.
    Brain & development, 2005, Volume: 27, Issue:8

    Topics: Animals; Antioxidants; Carnitine; Cell Death; Cells, Cultured; Cerebellum; Glutamic Acid; Hypoxia-Ischemia, Brain; Kainic Acid; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley

2005
Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats.
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Animals; Animals, Newborn; Anions; Brain; Cardiolipins; Carnitine; Carnitine O-Acetyltransferase; Glutamates; Glutamic Acid; Glycine; Hypoxia; Hypoxia-Ischemia, Brain; Immunohistochemistry; Lipid Metabolism; Mass Spectrometry; Microscopy, Fluorescence; Mitochondria; Phospholipids; Rats; Rats, Wistar; Superoxides; Time Factors; Vitamin B Complex

2006
Oxygen-glucose deprivation decreases glutathione levels and glutamate uptake in rat hippocampal slices.
    Brain research, 2006, Apr-14, Volume: 1083, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Antioxidants; Catalase; Cell Survival; Dithiothreitol; Down-Regulation; Glutamic Acid; Glutathione; Glutathione Reductase; Hippocampus; Hypoxia-Ischemia, Brain; Male; Organ Culture Techniques; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Synaptic Membranes; Synaptic Transmission

2006
Activation of 5-lipoxygenase after oxygen-glucose deprivation is partly mediated via NMDA receptor in rat cortical neurons.
    Journal of neurochemistry, 2006, Volume: 97, Issue:4

    Topics: Active Transport, Cell Nucleus; Animals; Animals, Newborn; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Encephalitis; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Leukotrienes; N-Methylaspartate; Neurons; Oxygen; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2006
GABAergic protection of hippocampal pyramidal neurons against glutamate insult: deficit in young animals compared to adults.
    Journal of neurophysiology, 2006, Volume: 96, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channels; Dendrites; Electrophysiology; Female; Gap Junctions; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, Glutamate

2006
Glutamate transporters GLAST and EAAT4 regulate postischemic Purkinje cell death: an in vivo study using a cardiac arrest model in mice lacking GLAST or EAAT4.
    Neuroscience research, 2006, Volume: 55, Issue:3

    Topics: Animals; Brain Infarction; Cell Death; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 4; Glutamic Acid; Heart Arrest; Heart Arrest, Induced; Hypoxia-Ischemia, Brain; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Purkinje Cells

2006
Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury.
    Experimental neurology, 2006, Volume: 199, Issue:1

    Topics: Acetylcholine; Animals; Animals, Newborn; beta-Galactosidase; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Therapy; Glutamic Acid; Hypoxia-Ischemia, Brain; Mice; Neurons; Neurotrophin 3; Phosphopyruvate Hydratase; Stem Cell Transplantation; Stem Cells; Transduction, Genetic

2006
Hypoxia-ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:2

    Topics: Animals; Animals, Newborn; Astrocytes; Axons; Brain Chemistry; Cell Lineage; Choroid; Ependyma; Glutamic Acid; Hypoxia-Ischemia, Brain; Microscopy, Immunoelectron; Oligodendroglia; Rats; Rats, Sprague-Dawley; Terminology as Topic

2007
Changes in diffusion parameters, energy-related metabolites and glutamate in the rat cortex after transient hypoxia/ischemia.
    Neuroscience letters, 2006, Aug-14, Volume: 404, Issue:1-2

    Topics: Animals; Cerebral Cortex; Disease Models, Animal; Energy Metabolism; Extracellular Space; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Kinetics; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Wistar

2006
Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors.
    Neurobiology of disease, 2007, Volume: 25, Issue:2

    Topics: Animals; Axons; Calcium; Calcium Signaling; Calpain; Cell Culture Techniques; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hypoxia; Hypoxia-Ischemia, Brain; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurotoxins; Receptors, Glutamate; Sodium; Sodium Channel Blockers; Sodium Channels; Wallerian Degeneration

2007
Glutamate-mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR-induced release of Ca++ from intracellular stores and is prevented by estradiol.
    The European journal of neuroscience, 2006, Volume: 24, Issue:11

    Topics: Animals; Asphyxia Neonatorum; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Disease Models, Animal; Down-Regulation; Estradiol; Female; Glutamic Acid; Hippocampus; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Intracellular Fluid; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate

2006
PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury.
    The European journal of neuroscience, 2007, Volume: 26, Issue:1

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cells, Cultured; Glutamic Acid; Hydantoins; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin

2007
Reperfusion accelerates acute neuronal death induced by simulated ischemia.
    Experimental neurology, 2007, Volume: 206, Issue:2

    Topics: Acidosis, Respiratory; Animals; Apoptosis; Cell Death; Cell Membrane; Cells, Cultured; Cytoskeleton; Glucose; Glutamic Acid; Hypercapnia; Hypoxia-Ischemia, Brain; Mice; Mice, Inbred C57BL; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Potassium; Reperfusion Injury; Time Factors

2007
Delayed IGF-1 administration rescues oligodendrocyte progenitors from glutamate-induced cell death and hypoxic-ischemic brain damage.
    Developmental neuroscience, 2007, Volume: 29, Issue:4-5

    Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Cells, Cultured; Cytoprotection; Drug Administration Schedule; Glutamic Acid; Hypoxia-Ischemia, Brain; Insulin-Like Growth Factor I; Myelin Basic Protein; Nerve Degeneration; Nerve Fibers, Myelinated; Nerve Growth Factors; Neurotoxins; Oligodendroglia; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stem Cells; Time Factors; Treatment Outcome

2007
Detection of cortical gray matter lesion in the late phase of mild hypoxic-ischemic injury by manganese-enhanced MRI.
    NeuroImage, 2008, Jan-15, Volume: 39, Issue:2

    Topics: Animals; Animals, Newborn; Brain Mapping; Cerebral Cortex; Data Interpretation, Statistical; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Hypoxia-Ischemia, Brain; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Manganese Poisoning; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2008
Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine.
    Brain research, 2008, Jan-10, Volume: 1188

    Topics: Aging; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Biological Transport, Active; Brain Infarction; Cell Survival; Energy Metabolism; Glutamic Acid; Guanosine; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar

2008
Deferoxamine decreases the excitatory amino acid levels and improves the histological outcome in the hippocampus of neonatal rats after hypoxia-ischemia.
    Pharmacological research, 2008, Volume: 57, Issue:1

    Topics: Animals; Animals, Newborn; Aspartic Acid; Deferoxamine; Excitatory Amino Acids; Female; Glutamic Acid; Hippocampus; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Ischemia, Brain; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar

2008
Low endogenous G-protein-coupled receptor kinase 2 sensitizes the immature brain to hypoxia-ischemia-induced gray and white matter damage.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Mar-26, Volume: 28, Issue:13

    Topics: Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Brain Injuries; G-Protein-Coupled Receptor Kinase 2; Gene Expression Regulation, Developmental; Glutamic Acid; Hypoxia-Ischemia, Brain; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Basic Protein; Neuroglia; Neurons; Neutrophil Infiltration; Peroxidase; Regional Blood Flow; Subcellular Fractions; Time Factors

2008
Excitatory amino acids and taurine levels in cerebrospinal fluid of hypoxic ischemic encephalopathy in newborn.
    Clinical neurology and neurosurgery, 1999, Volume: 101, Issue:3

    Topics: Aspartic Acid; Asphyxia Neonatorum; Case-Control Studies; Excitatory Amino Acids; Female; Follow-Up Studies; Glutamic Acid; Glycine; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Taurine

1999
Quantitative evaluation of extracellular glutamate concentration in postischemic glutamate re-uptake, dependent on brain temperature, in the rat following severe global brain ischemia.
    Brain research, 2000, May-02, Volume: 864, Issue:1

    Topics: Animals; Body Temperature; Brain; Cerebrovascular Circulation; Cytoplasm; Disease Models, Animal; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Neurons; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury

2000
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
    Journal of neuroscience research, 2000, Oct-01, Volume: 62, Issue:1

    Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols

2000
Two distinct components of initial glutamate release synchronized with anoxic depolarization in rat global brain ischemia.
    Neuroreport, 2000, Sep-11, Volume: 11, Issue:13

    Topics: Animals; Dialysis; Disease Models, Animal; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Membrane Potentials; Neurons; Rats; Rats, Inbred WKY

2000
Ischemia-induced phosphorylation of initiation factor 2 in differentiated PC12 cells: role for initiation factor 2 phosphatase.
    Journal of neurochemistry, 2000, Volume: 75, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cell Survival; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Glutamic Acid; Guanosine Triphosphate; Hypoxia-Ischemia, Brain; Neurons; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Proteins; Rats

2000
A brain slice model for in vitro analyses of astrocytic gap junction and connexin43 regulation: actions of ischemia, glutamate and elevated potassium.
    The European journal of neuroscience, 2000, Volume: 12, Issue:12

    Topics: 2-Amino-5-phosphonovalerate; Animals; Astrocytes; Brain; Connexin 43; Gap Junctions; Glutamic Acid; Hypoxia-Ischemia, Brain; In Vitro Techniques; Models, Neurological; Phosphorylation; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2000
NBQX attenuates excitotoxic injury in developing white matter.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Dec-15, Volume: 20, Issue:24

    Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Male; Microinjections; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate

2000
Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture.
    Neuroscience, 2001, Volume: 102, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Count; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; GABA Modulators; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Pentobarbital; Picrotoxin; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Stereoisomerism

2001
A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke.
    Brain research, 2001, Feb-23, Volume: 892, Issue:2

    Topics: Animals; Aspartic Acid; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Mice; Mice, Inbred C57BL; Middle Cerebral Artery; Neuroprotective Agents; Postural Balance; Receptors, N-Methyl-D-Aspartate; Stroke

2001
Intracellular calcium accumulation during the evolution of hypoxic-ischemic brain damage in the immature rat.
    Brain research. Developmental brain research, 2001, Jan-31, Volume: 126, Issue:1

    Topics: Animals; Brain; Calcium Chloride; Calcium Radioisotopes; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroglia; Neurons; Rats

2001
Glutamate in cerebral tissue of asphyxiated neonates during the first week of life demonstrated in vivo using proton magnetic resonance spectroscopy.
    Biology of the neonate, 2001, Volume: 79, Issue:3-4

    Topics: Asphyxia Neonatorum; Basal Ganglia; Brain Chemistry; Gestational Age; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2001
The N-methyl-D-aspartate antagonist memantine has no neuroprotective effect during hypothermic circulatory arrest: a study in the chronic porcine model.
    The Journal of thoracic and cardiovascular surgery, 2001, Volume: 121, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Cardiopulmonary Bypass; Electroencephalography; Female; Glucose; Glutamic Acid; Glycerol; Heart Arrest, Induced; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Lactic Acid; Memantine; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Swine

2001
17beta-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: a new neuroprotective pathway.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Animals; Brain Injuries; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Estradiol; Extracellular Space; Glutamic Acid; Hypoxia-Ischemia, Brain; Lactic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar

2001
Excitotoxic preconditioning elicited by both glutamate and hypoxia and abolished by lactate transport inhibition in rat hippocampal slices.
    Neuroscience letters, 2001, Jul-20, Volume: 307, Issue:3

    Topics: Action Potentials; Animals; Carrier Proteins; Coumaric Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Lactic Acid; Male; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley

2001
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
    Experimental brain research, 2001, Volume: 138, Issue:3

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Kidney; Lactic Acid; Maternal Behavior; Microdialysis; Pyruvic Acid; Quinoxalines; Rats; Receptors, Glutamate; Survival Rate; Treatment Outcome

2001
Prolonged suppression of brain nitric oxide synthase activity by 7-nitroindazole protects against cerebral hypoxic-ischemic injury in neonatal rat.
    Brain & development, 2001, Volume: 23, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Brain; Dose-Response Relationship, Drug; Female; Glutamic Acid; Hypoxia-Ischemia, Brain; Indazoles; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Rats

2001
Altered expressions of glutamate transporter subtypes in rat model of neonatal cerebral hypoxia-ischemia.
    Brain research. Developmental brain research, 2001, Dec-31, Volume: 132, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Apoptosis; Brain; Carrier Proteins; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glial Fibrillary Acidic Protein; Gliosis; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hypoxia-Ischemia, Brain; Immunohistochemistry; Rats; Rats, Wistar; Symporters

2001
Differential regulation of glial cell line-derived neurotrophic factor (GDNF) mRNA expression during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats.
    Glia, 2002, Volume: 37, Issue:1

    Topics: Animals; Astrocytes; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fetus; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Hydrogen Peroxide; Hypoxia-Ischemia, Brain; Nerve Growth Factors; Nerve Tissue Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2002
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
    The European journal of neuroscience, 2002, Volume: 15, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2002
Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats.
    Neuroscience letters, 2002, Mar-08, Volume: 320, Issue:3

    Topics: Amino Acids; Amygdala; Animals; Cerebral Infarction; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hypoxia-Ischemia, Brain; Male; Microdialysis; Nitric Oxide; Nootropic Agents; Prefrontal Cortex; Pyrrolidinones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Synaptic Transmission; Up-Regulation

2002
NOC/oFQ and NMDA contribute to piglet hypoxic ischemic hypotensive cerebrovasodilation impairment.
    Pediatric research, 2002, Volume: 51, Issue:5

    Topics: Animals; Animals, Newborn; Cerebrovascular Circulation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hypotension; Hypoxia-Ischemia, Brain; Intracranial Hypertension; Male; N-Methylaspartate; Narcotic Antagonists; Neuroprotective Agents; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Pia Mater; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Shock, Hemorrhagic; Swine; Vasodilation

2002