glutamic acid has been researched along with Glioma in 185 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (3.24) | 18.7374 |
| 1990's | 37 (20.00) | 18.2507 |
| 2000's | 50 (27.03) | 29.6817 |
| 2010's | 69 (37.30) | 24.3611 |
| 2020's | 23 (12.43) | 2.80 |
| Authors | Studies |
|---|---|
| Alberto-Silva, C; Carrettiero, DC; Costa, RT; Ribeiro, CAJ; Santos, MB | 1 |
| Ates, G; Beckers, P; Belo do Nascimento, I; Desmet, N; Hermans, E; Joris, V; Massie, A; Verfaillie, M | 1 |
| Chinnaiyan, P; Cho, K; Dunphy, MP; Frankfater, C; Gass, H; Graham, MS; Grkovski, M; Ippolito, JE; Jones, JK; Krebs, S; Luo, J; Mauguen, A; Nunez, E; Patti, GJ; Rubin, JB; Schaefer, J; Spitz, DR; Sponagel, J; Tinkum, KL; Tung, O; Zhang, S | 1 |
| Feyissa, AM; Quiñones-Hinojosa, A; Rosenfeld, SS | 1 |
| Demirdizen, E; Deo, M; Jimenez-Cowell, K; Kilic, O; Kim, H; Park, JW; Turcan, Ş | 1 |
| Conejos-Sánchez, I; Masiá, E; Melnyk, T; Vicent, MJ; Zagorodko, O | 1 |
| Dahlmanns, JK; Dahlmanns, M; Savaskan, N; Steiner, HH; Yakubov, E | 1 |
| Ashkan, K; Kumaria, A | 1 |
| Arzt, M; Aziz-Bose, R; Barron, T; Chau, I; Du, PP; Geraghty, AC; Gillespie, SM; Hartmann, GG; Hui, A; Ivec, AE; Keough, MB; Kim, YS; Maleki Jahan, S; Mancusi, R; Monje, M; Mulinyawe, S; Ni, L; Ponnuswami, A; Shamardani, K; Silva-Torres, A; Spitzer, A; Su, M; Suvà, ML; Taylor, KR; Tirosh, I; Venkatesh, HS; Woo, PJ; Yalçin, B; Zhang, H | 1 |
| Galland, F; Gonçalves, CA; Leite, MC; Seady, M; Smaili, SS; Taday, J | 1 |
| Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Mayer, J; Porath, K; Resch, T | 1 |
| Campbell, SC; Chaunsali, L; Mills, WA; Muñoz-Ballester, C; Robel, S; Sontheimer, H; Yang, JH | 1 |
| Bowles, C; Chase, LA; Engelsman, SB; Flores, G; King, AG; Robinson, AE; Rothstein, J; Schiller, N; Smith, SL; VerHeulen Kleyn, M | 1 |
| Weller, M; Wirsching, HG | 1 |
| Bagga, P; Detre, JA; Haris, M; Reddy, R; Rich, LJ; Schnall, MD; Wilson, NE | 1 |
| Gillespie, DL; Huang, LE; Jensen, RL; Tiburcio, PDB | 1 |
| Colak, M; Yalçın, GD | 1 |
| Asklund, T; Bergenheim, AT; Bergström, P; Björn, E; Johansson, M; Tabatabaei, P | 1 |
| Batsios, G; Gillespie, AM; Lakhani, A; Molloy, AR; Najac, C; Pieper, RO; Radoul, M; Ronen, SM; Subramani, E; Viswanath, P | 1 |
| Gonçalves, LG; Martins, F; Pojo, M; Serpa, J | 1 |
| Antonelli, M; Aronica, E; Barba, C; Bertero, L; Buccoliero, AM; Caporalini, C; Conti, V; Diomedi-Camassei, F; Donofrio, V; Genitori, L; Gessi, M; Giangaspero, F; Gianno, F; Giordano, F; Guerrini, R; Migliastro, I; Moscardi, S; Mussa, F; Rossi, S; Santi, M; Sardi, I; Scagnet, M | 1 |
| Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S | 1 |
| Liu, W; Liu, Y; Sun, X; Yang, S; Yao, X; Yu, H; Zhao, C; Zhou, F | 1 |
| Catalano, M; Civiero, L; D'Agnano, I; Familiari, G; Familiari, P; Iovino, L; Limatola, C; Monaco, L; Raspa, M; Relucenti, M; Scavizzi, F; Serpe, C | 1 |
| Khurshed, M; Leenders, WP; Lenting, K; Molenaar, RJ; van Noorden, CJF | 1 |
| Buchfelder, M; Chen, D; Eyupoglu, IY; Fan, Z; Rauh, M; Savaskan, N | 1 |
| Chen, YM; Gao, YT; Guo, D; Li, T; Li, YL; Wang, GL; Wang, HY; Wang, XY; Yang, CY; Yang, Z; Zhu, M | 1 |
| Daniels, RL; Hill, NR; Indart, MC; Strong, AD | 1 |
| Cudalbu, C; Gruetter, R; Hamou, MF; Hegi, ME; Lai, M; Lanz, B; Poitry-Yamate, C; Vassallo, I | 1 |
| Catacuzzeno, L; Catalano, M; D'Alessandro, G; Di Angelantonio, S; Di Castro, MA; Grassi, F; Grimaldi, A; Lauro, C; Limatola, C; Pagani, F; Sforna, L; Singh, V; Wulff, H | 1 |
| Fan, ZL; Jin, BH; Lin, MT; Shen, BX; Sohawon, Y; Tong, MQ; Xu, HL; Yao, Q; Zhao, YZ; Zhu, QY; ZhuGe, DL | 1 |
| Botman, D; de Bitter, T; Heerschap, A; Hendriks, W; Huynen, MA; Khurshed, M; Kusters, B; Leenders, WPJ; Lenting, K; Molenaar, RJ; Peeters, TH; Span, PN; Ter Laan, M; van den Heuvel, CNAM; van Ewijk, A; van Lith, SAM; van Noorden, CJF; Verrijp, K | 1 |
| Dalley, CB; Wolfe, BB; Wroblewska, B; Wroblewski, JT | 1 |
| Hayakawa, Y; Ibusuki, Y; Kimata, S; Kuriyama, T | 1 |
| Cerdán, S; García-Martín, ML; Lopez-Larrubia, P; Mucci, A; Righi, V; Schenetti, L; Tugnoli, V | 1 |
| Asara, JM; Bernstein, BE; Briggs, KJ; Cahill, DP; Carrasco, RD; Chakraborty, AA; DiNatale, GJ; Haigis, MC; Islam, M; Kaelin, WG; Khanal, J; Ligon, KL; Looper, RE; Mayers, JR; McBrayer, SK; Metallo, CM; Olenchock, BA; Parker, SJ; Robbins, AK; Sarosiek, KA; Sewastianik, T; Shareef, SJ; Shi, DD; Spinelli, JB; Tateishi, K; Vander Heiden, MG; Yennawar, NH | 1 |
| Akashi, K; Baba, E; Hirata, Y; Kamenori, S; Mitsuishi, Y; Nagano, O; Okazaki, S; Sampetrean, O; Saya, H; Shintani, S; Suina, K; Takahashi, F; Takahashi, K; Tsuchihashi, K; Yamasaki, J | 1 |
| Dankó, T; Horváth, G; Hujber, Z; Jeney, A; Krencz, I; Leenders, WPJ; Mészáros, K; Petővári, G; Rajnai, H; Sebestyén, A; Szoboszlai, N; Tretter, L | 1 |
| Bruzzone, MG; Cantini, G; Cominelli, M; Corbetta, C; Di Ianni, N; Finocchiaro, G; Patanè, M; Pellegatta, S; Pisati, F; Poliani, PL; Pollo, B; Zucca, I | 1 |
| Arumugam, PU; DeCoster, MA; Kansakar, U; Madadi, M; Murray, TA; Nguyen, NH; Scoggin, JL; Siddiqui, S; Tan, C | 1 |
| Davis, KA; Desmond, P; Drummond, K; Glarin, R; Hariharan, H; Kwan, P; Moffat, BA; Morokoff, A; Nanga, RPR; Neal, A; O'Brien, TJ; Reddy, R; Shinohara, RT; Stein, JM | 1 |
| Batchelor, TT; Borger, DR; Chi, AS; Dias-Santagata, D; Ellisen, LW; Iafrate, AJ; Louis, DN; Yang, D | 1 |
| Bachoo, R; Choi, C; Deberardinis, R; Dimitrov, I; Ganji, S; Hulsey, K; Kovacs, Z; Madan, A; Maher, E; Malloy, C; Mendelsohn, D; Mickey, B; Pichumani, K; Zhang, S | 1 |
| De Leo, JA; Jacobs, VL | 1 |
| Bobermin, LD; Dall'Igna, OP; Quincozes-Santos, A; Souza, DO | 1 |
| Blecic, S; De Witte, O; Lefranc, F; Rynkowski, M | 1 |
| Robert, SM; Sontheimer, H | 1 |
| Bjorksten, A; Desmond, PM; Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BA; Morokoff, AP; O'Brien, TJ | 1 |
| Anghileri, E; Bertolino, N; Bruzzone, MG; Burns, B; Finocchiaro, G; Ghielmetti, F; Marchionni, C; Minati, L | 1 |
| Cavalheiro, MM; de Oliveira, DL; de Souza, DO; Filippi-Chiela, EC; Lenz, G; Pereira, MS; Thomé, CC; Zenki, K | 1 |
| Drummond, KJ; Kaye, AH; Liubinas, SV; Moffat, BM; Morokoff, AP; O'Brien, TJ | 1 |
| Bjerkvig, R; Leenders, WP; Molenaar, R; Navis, AC; Niclou, SP; Tops, B; van Lith, SA; van Noorden, CJ; Verrijp, K; Wesseling, P | 1 |
| Cai, L; Chaumeil, MM; Eriksson, P; Larson, PE; Lupo, JM; Nelson, SJ; Phillips, JJ; Pieper, RO; Robinson, AE; Ronen, SM; Vigneron, DB; Woods, SM | 1 |
| Kang, DZ; Lin, RY; Wang, W; Yao, PS; Ye, B; Ye, ZC | 1 |
| Chen, R; Daemen, A; Deng, Y; Forrest, WF; Friedman, LS; Hatzivassiliou, G; Hedehus, M; Kharbanda, S; Kwong, M; Nishimura, MC; Peale, F; Phillips, HS | 1 |
| Chen, J; Gao, H; He, Q; Jiang, X; Qian, J; Ruan, S; Shen, S; Yang, W; Zhu, J | 1 |
| McGovern, RA; McKhann, GM; Nelp, TB | 1 |
| Bachoo, RM; Baek, HM; DeBerardinis, RJ; Kovacs, Z; Maher, EA; Malloy, CR; Mashimo, T; Mickey, B; Pichumani, K; Ratnakar, J | 1 |
| Cardona-Gómez, GP; Palacio-Castañeda, V; Posada-Duque, RA | 1 |
| Hansen, H; Hashizume, Y; Loiacono, KA; Rojas, C; Sahni, V; Sattler, R; Slusher, BS; Tendyke, K; Thomas, AG | 1 |
| Dembitskaya, Y; Kazantsev, V; Medyanik, I; Mishchenko, M; Tyurikova, O; Vedunova, M; Yashin, K | 1 |
| Di, X; Fu, Q; He, Z; Kan, Q; Li, L; Liu, H; Lu, T; Sun, J; Wang, Y; Zhang, S | 1 |
| Huberfeld, G; Vecht, CJ | 1 |
| Abe, S; Akashi, K; Akiyama, T; Baba, E; Furnari, FB; Ishikawa, M; Iwasaki, Y; Masuko, T; Morikawa, T; Nagane, M; Nagano, O; Ohmura, M; Okazaki, S; Onishi, N; Sampetrean, O; Saya, H; Seishima, R; Shimizu, M; Suematsu, M; Takao, A; Tsuchihashi, K; Wakimoto, H; Yoshikawa, M | 1 |
| Hosoda, K; Irino, Y; Itoh, T; Kohmura, E; Kyotani, K; Mizukawa, K; Mukasa, A; Nagashima, H; Sakata, J; Sasaki, R; Sasayama, T; Sato, N; Takeuchi, Y; Tanaka, K; Yamamoto, Y | 1 |
| Gottschalk, M; Grand, S; Lamalle, L; Le Bas, JF; Segebarth, C; Troprès, I | 1 |
| Bjorksten, AR; Kwan, P; Morokoff, A; Neal, A; O'Brien, TJ; Yuen, T | 1 |
| MacKenzie, G; Maguire, J; Moss, SJ; O'Toole, KK | 1 |
| Bergenheim, AT; Bergström, P; Brännström, T; Siesjö, P; Tabatabaei, P; Visse, E | 1 |
| Albrecht, J; Szeliga, M | 1 |
| Ding, MP; Ding, Y; Guo, Y; Shen, CH; Tang, YL; Wang, S; Zhang, YX; Zheng, Y; Zhu, JM | 1 |
| Bergenheim, AT; Bergström, P; Henriksson, R; Tabatabaei, P | 1 |
| Simpkins, JW; Yi, KD | 1 |
| Bergenheim, AT; Lindvall, P; Roslin, M | 1 |
| Fan, GG; Guo, QY; Sun, HZ; Wang, GL | 1 |
| Albrecht, J; Alonso, FJ; Hilgier, W; Lobo, C; Márquez, J; Matyja, E; Obara-Michlewska, M; Szeliga, M; Łazarczyk, M | 1 |
| de Souza, DF; Gelain, DP; Gonçalves, CA; Gottfried, C; Latini, A; Moreira, JC; Nardin, P; Quincozes-Santos, A | 1 |
| Carpenter, KL; Hutchinson, PJ; Marcus, HJ; Price, SJ | 1 |
| Biber, K; Boddeke, HW; Brouwer, N; de Jong, EK; Eisel, UL; Granic, I; Liem, RS; Stanulovic, V; Vinet, J | 1 |
| Eyüpoglu, IY; Hahnen, E; Hauke, J; Savaskan, NE; Seufert, S; Tränkle, C | 1 |
| Bennett, BD; Dang, CV; Ferraris, DV; Gao, P; Joshi, AD; Rabinowitz, JD; Riggins, GJ; Rojas, CJ; Seltzer, MJ; Slusher, BS; Thomas, AG; Tsukamoto, T | 1 |
| Liu, SC; Wang, YY; Yang, Z; Zhang, T | 1 |
| Lu, CL; Sun, XJ; Wang, CH; Wang, XQ | 1 |
| Bannai, S; Beck, H; Conrad, M; De Bundel, D; Fernando, R; Kim, SW; Kobayashi, S; Massie, A; Michotte, Y; Plesnila, N; Sato, H; Schallier, A; Smolders, I; Vermoesen, K | 1 |
| de Groot, J; Sontheimer, H | 1 |
| Hisaoka, K; Kajiatani, N; Shibasaki, C; Takebayashi, M; Tsuchioka, M; Yano, R | 1 |
| Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Anderson, RA; Panickar, KS | 1 |
| Banerjee, A; Das, S; Joardar, A; Naskar, J; Roy, S | 1 |
| Choi, JK; Das, SK; Dash, R; Emdad, L; Fisher, PB; Howlett, EL; Jeon, HY; Kang, DC; Kegelman, TP; Kim, K; Kim, SH; Lee, SG; Sarkar, D; Su, ZZ; Yoo, BK | 1 |
| Buckingham, SC; Campbell, SL; Haas, BR; Montana, V; Ogunrinu, T; Robel, S; Sontheimer, H | 1 |
| Kuroiwa, M; Matsuyama, D; Mochida, J; Okada, Y; Sakabe, K; Suyama, K; Watanabe, M | 1 |
| Simon, M; von Lehe, M | 1 |
| Cheng, Y; Du, P; Feng, H; Hu, S; Li, F; Li, J; Li, M; Yi, L | 1 |
| Galeffi, F; Turner, DA | 1 |
| Berkutzki, T; Cooper, I; Mohar, B; Ruban, A; Teichberg, VI | 1 |
| Buckingham, SC; Campbell, SL; Sontheimer, H | 1 |
| Roelcke, U; Rüegg, S | 1 |
| Bjorksten, A; D'Abaco, G; Drummond, KJ; Finch, S; Kaye, AH; Morokoff, AP; O'Brien, TJ; Paradiso, L; Powell, KL; Reid, CA; Rosenthal, MA; Wong, D; Yuen, TI | 1 |
| Albrecht, J; Dolińska, M; Dybel, A; Kocki, T; Turski, WA; Urbańska, EM | 1 |
| Rothstein, JD | 1 |
| Butchbach, ME; Guo, H; Lai, L; Lin, CL | 1 |
| Chen, XL; Fukuda, Y; Hashii, M; Higashida, H; Hoshi, N; Hossain, KZ; Mochida, S; Nakanishi, S; Noda, M; Shigemoto, R; Shin, Y; Yokoyama, S; Zhang, JS | 1 |
| Sontheimer, H | 3 |
| Huang, Y; Zuo, Z | 1 |
| Gao, Y; Lei, LS; Wu, SG | 1 |
| Buydens, LM; Heerschap, A; Melssen, WJ; Postma, GJ; Simonetti, AW; van der Graaf, M | 1 |
| Franco, R; Ordaz, B; Pasantes-Morales, H; Vaca, L | 1 |
| Ding, JH; He, HR; Hu, G; Yao, HH | 1 |
| Sutherland, ML; Zhou, J | 1 |
| Higuchi, Y; Yoshimoto, T | 1 |
| Brennan, L; Hewage, C; Malthouse, JP; McBean, GJ | 1 |
| McKnight, TR | 1 |
| Erol, K; Kabadere, S; Korkmaz, S; Oztopçu, P; Uyar, R | 1 |
| Bedioui, F; Blöchl, A; Castillo, J; Csöregi, E; Isik, S; Oni, J; Pereira-Rodrigues, N; Schuhmann, W | 1 |
| da Rocha, AB; Diel, CL; Farias, CB; Grivicich, I; Kowaleski, G; Mondadori, E; Regner, A; Schunemann, DP; Schwartsmann, G | 1 |
| Hermans, E; Maloteaux, JM; Najimi, M | 1 |
| González, MI; Krizman-Genda, E; Robinson, MB; Zelenaia, O | 1 |
| Banik, NL; Ray, SK; Sribnick, EA | 1 |
| Ishiuchi, S; Ozawa, S; Tsuzuki, K; Yoshida, Y | 1 |
| Ichida, S; Imanishi, T; Kawaguchi, A; Matsushima, K; Wada, T; Yoshida, S | 1 |
| de Almeida, LM; dos Santos, AQ; Funchal, C; Gonçalves, CA; Gottfried, C; Jacques-Silva, MC; Nardin, P; Wofchuk, ST | 1 |
| Allritz, C; Engele, J; Rein, T; Zschocke, J | 1 |
| Igarashi, H; Kimura, T; Kwee, IL; Nakada, T; Ohkubo, M | 1 |
| Birgner, C; Elfverson, M; Frändberg, PA; Johansson, T; Le Grevès, P; Nyberg, F | 1 |
| Alatorre-Carranza, Mdel P; Delgado-Rizo, V; Duenas-Jimenez, JM; Duenas-Jimenez, SH; Guerrero-Cázares, H; Guerrero-Hernández, A; Mendoza-Magana, ML; Morales-Villagran, A; Ramirez-Herrera, MA; Segovia, J | 1 |
| Kitano, H; Shinohara, H; Wang, F; Zakir Hossain, SM | 1 |
| Fuda, H; Hanyu, O; Kohjitani, A; Strott, CA | 1 |
| Cheng, FC; Cheng, H; Chou, SC; Fu, YS; Fu, YY; Hsu, SY; Kao, LS; Lin, YY; Shih, YH; Tsai, TH; Wang, JY | 1 |
| Kitano, H; Shinohara, H; Zakir Hossain, SM | 1 |
| Hermans, E; Vanhoutte, N | 1 |
| Browning, ET; Nicklas, WJ | 1 |
| Hatakenaka, S; Higashida, H; Higuchi, Y; Kato, S; Negishi, K | 1 |
| Martin, DL; Waniewski, RA | 1 |
| Bansinath, M; Garg, UC; Turndorf, H | 1 |
| Shinagawa, S | 1 |
| Mikuni, M; Saitoh, K; Shinno, H; Takahashi, K; Tomita, U; Yamawaki, S | 2 |
| Cox, AJ; Lee, RK; Nitsch, RM; Wurtman, RJ | 1 |
| Canioni, P; Merle, M; Portais, JC; Schuster, R | 1 |
| Chen, DZ; Chen, SH; Katsura, M; Kuriyama, K; Ohkuma, S | 1 |
| Amano, S; Hazama, F; Ishiko, T; Ohashi, M | 1 |
| Els, T; Gyngell, ML; Hoehn-Berlage, M; Hossmann, KA | 1 |
| Amano, S; Handa, J; Hazama, F; Ohashi, M | 1 |
| Coyle, AJ; Dowd, LA; Pritchett, DB; Robinson, MB; Rothstein, JD | 1 |
| Kato, S; Mawatari, K; Sugitani, K; Takadera, T; Yasui, Y | 1 |
| Canioni, P; Merle, M; Portais, JC; Voisin, P | 1 |
| Haghighat, N; McCandless, DW | 1 |
| Albasanz, JL; Martín, M; Ros, M | 1 |
| Baethmann, A; Chang, RC; Peters, J; Plesnila, N; Staub, F | 1 |
| Han, D; Kobayashi, MS; Packer, L; Roy, S; Sen, CK; Tritschler, HJ | 1 |
| Higuchi, Y; Matsukawa, S | 1 |
| Kondakova, LI; Medvedev, AE; Moskvitina, TA; Navasardyantz, DG; Podobed, OV; Tsvetkova, TA; Yakusheva, IV | 1 |
| Debinski, W; Gibo, DM; Kealiher, A; Obiri, NI; Puri, RK | 1 |
| Albasanz, JL; Fernández, M; Martín, M; Ros, M | 1 |
| Hartmann, J; Kettenmann, H; Labrakakis, C; Patt, S | 1 |
| Kort, JJ | 1 |
| DelaBarre, L; Garwood, M; Gruetter, R; High, WB; Merkle, H; Mescher, M; Terpstra, M | 1 |
| Hirano, M; Koshimoto, H; Suga, T; Takayanagi, M; Watanabe, A | 1 |
| Bouzier, AK; Canioni, P; Merle, M; Quesson, B; Valeins, H | 1 |
| Sontheimer, H; Ye, ZC | 1 |
| Choe, BK; Kim, SK; Kwon, GY; Shin, SW | 1 |
| Rothstein, JD; Sontheimer, H; Ye, ZC | 1 |
| Behrens, PF; Draeger, J; Hennig, J; Langemann, H; Strohschein, R | 1 |
| Hashimoto, M; Hsu, L; Mallory, M; Masliah, E; Rockenstein, E | 1 |
| Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A | 1 |
| Higuchi, Y | 1 |
| Brem, H; Rothstein, JD | 1 |
| Arcuino, G; Gao, Q; Lin, JH; Nedergaard, M; Takano, T; Yang, J | 1 |
| Fernandez, M; Luis Albasanz, J; Martín, M | 1 |
| Harrison, PJ; Meller, R; Sharp, T | 1 |
| Bangalore, L; Bormann, BJ; Cao, H; Stern, DF | 1 |
| Kato, S; Kuo, CH; Mawatari, K; Negishi, K | 1 |
| Barańska, J; Czarny, M; Kaczmarek, L; Sabała, P; Ucieklak, A | 1 |
| Cheng, Y; Sun, AY; Sun, GY | 1 |
| Baethmann, A; Kempski, O; Schneider, GH; Staub, F; Weigt, H | 1 |
| Baethmann, A; Kempski, O; Schneider, GH | 1 |
| Allard, M; Biran, M; Caille, JM; Canioni, P; Kien, P; Labouesse, J; Merle, M; Pianet, I; Portais, JC; Raffard, G | 1 |
| Gotoh, F; Shinohara, T; Tomita, M | 1 |
| Bannai, S; Cho, Y | 1 |
| Bartel, R; Bigner, DD; Campbell, GL; Freidman, HS | 1 |
| Hertz, L; Lacoste, L; Lapointe, J | 1 |
| Biegel, JA; Bigner, DD; Bigner, SH; Eng, LF; Friedman, HS; Gebhardt, R; Mark, J; Wikstrand, CJ | 1 |
17 review(s) available for glutamic acid and Glioma
| Article | Year |
|---|---|
Altered glutamatergic and inflammatory pathways promote glioblastoma growth, invasion, and seizures: An overview.
Topics: Brain Neoplasms; Glioblastoma; Glioma; Glutamic Acid; Humans; Seizures; Tumor Microenvironment | 2022 |
Glial Glutamate Transporter-Mediated Plasticity: System x
Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amino Acid Transport System y+; Amyotrophic Lateral Sclerosis; Antioxidants; Cystine; Glioma; Glutamic Acid; Humans; Microglia; Multiple Sclerosis; Parkinson Disease | 2023 |
Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas.
Topics: Central Nervous System; Glioma; Glutamic Acid; Glutamine; Glutathione; Humans; Neurotransmitter Agents; Oxidation-Reduction; Oxidative Stress | 2020 |
[Glutamate and malignant gliomas, from epilepsia to biological aggressiveness: therapeutic implications].
Topics: Benzodiazepines; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Humans; Memantine; Neoplasm Invasiveness; Neuroglia; Neurons; Receptors, AMPA; Receptors, Glutamate; Seizures; Sulfasalazine | 2013 |
Glutamate transporters in the biology of malignant gliomas.
Topics: Amino Acid Transport System X-AG; Brain Neoplasms; Glioma; Glutamic Acid; Glutathione; Humans; Receptors, Glutamate | 2014 |
Tumour associated epilepsy and glutamate excitotoxicity in patients with gliomas.
Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Quality of Life; Synaptic Transmission | 2014 |
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemotaxis; Enzyme Inhibitors; Glioma; Glutamic Acid; Glutamine; Humans; Isocitrate Dehydrogenase | 2014 |
Perspectives in Intraoperative Diagnostics of Human Gliomas.
Topics: Brain Neoplasms; Cell Movement; Computational Biology; Glioma; Glutamic Acid; Humans; Image-Guided Biopsy; Intraoperative Period; Magnetic Resonance Imaging; Optical Imaging; Surgery, Computer-Assisted; Ultrasonography | 2015 |
Seizures and gliomas--towards a single therapeutic approach.
Topics: Animals; Anticonvulsants; Brain Neoplasms; GABAergic Neurons; Glioma; Glutamic Acid; Humans; Seizures; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
[Progress in the study of the chemical synapse in glioma-associated epileptogenesis].
Topics: Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans; Neurotransmitter Agents; Neurotransmitter Transport Proteins; Synapses | 2008 |
Glutamate and the biology of gliomas.
Topics: Animals; Benzodiazepines; Brain; Brain Neoplasms; Glioma; Glutamic Acid; Humans; Models, Biological; Receptors, AMPA; Signal Transduction | 2011 |
Exploiting metabolic differences in glioma therapy.
Topics: Brain Neoplasms; Glioma; Glutamic Acid; Glutamine; Humans; Hypoxia-Inducible Factor 1; NAD; NADP; Signal Transduction | 2012 |
Malignant gliomas: perverting glutamate and ion homeostasis for selective advantage.
Topics: Animals; Astrocytes; Cell Movement; Chloride Channels; Genes, Tumor Suppressor; Glioma; Glutamic Acid; Homeostasis; Humans; Ion Channels; Membrane Transport Proteins; Nervous System; Neurons; Neurotransmitter Agents; Oligodendroglia; Receptors, Glutamate; Stem Cells | 2003 |
Ion channels and amino acid transporters support the growth and invasion of primary brain tumors.
Topics: Amino Acid Transport Systems; Animals; Brain Neoplasms; Cell Division; Glioma; Glutamic Acid; Humans; Ion Channels; Neoplasm Invasiveness | 2004 |
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Phosphocreatine | 2004 |
A role for glutamate in growth and invasion of primary brain tumors.
Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents; Brain Neoplasms; Cystine; Glioma; Glutamic Acid; Humans; Neoplasm Invasiveness | 2008 |
Swelling of C6 glioma cells and astrocytes from glutamate, high K+ concentrations or acidosis.
Topics: Acidosis, Lactic; Animals; Astrocytes; Brain Neoplasms; Cell Hypoxia; Cell Size; Glioma; Glutamates; Glutamic Acid; Iodoacetates; Iodoacetic Acid; Ouabain; Potassium; Rats; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured | 1992 |
168 other study(ies) available for glutamic acid and Glioma
| Article | Year |
|---|---|
Methylmalonic Acid Impairs Cell Respiration and Glutamate Uptake in C6 Rat Glioma Cells: Implications for Methylmalonic Acidemia.
Topics: Adenosine Triphosphate; Animals; Cell Respiration; Glioma; Glutamic Acid; Methylmalonic Acid; Rats | 2023 |
AMPK Modulates the Metabolic Adaptation of C6 Glioma Cells in Glucose-Deprived Conditions without Affecting Glutamate Transport.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Glioma; Glucose; Glutamic Acid; Humans | 2022 |
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment.
Topics: Animals; Brain Neoplasms; Citric Acid Cycle; Female; Glioma; Glutamic Acid; Glutamine; Humans; Male; Mice; Pyruvate Carboxylase; Sex Characteristics | 2022 |
CIC reduces xCT/SLC7A11 expression and glutamate release in glioma.
Topics: Amino Acid Transport System y+; Glioma; Glutamic Acid; Humans; Neurons; Oligodendroglioma; Repressor Proteins | 2023 |
Rational design of poly-L-glutamic acid-palbociclib conjugates for pediatric glioma treatment.
Topics: Brain Neoplasms; Child; Diffuse Intrinsic Pontine Glioma; Glioma; Glutamic Acid; Humans | 2023 |
Novel therapeutic strategies in glioma targeting glutamatergic neurotransmission.
Topics: Anticonvulsants; Brain Neoplasms; Glioblastoma; Glioma; Glutamic Acid; Humans; Synaptic Transmission | 2023 |
Glioma synapses recruit mechanisms of adaptive plasticity.
Topics: Adaptation, Physiological; Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Proliferation; Child; Disease Progression; Glioma; Glutamic Acid; Humans; Neuronal Plasticity; Neurons; Optogenetics; Receptor, trkB; Receptors, AMPA; Signal Transduction; Synapses; Tumor Microenvironment | 2023 |
Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells.
Topics: Animals; Astrocytes; Brain Neoplasms; Cell Communication; Cell Line; Cell Proliferation; Glial Fibrillary Acidic Protein; Glioma; Glucose; Glutamic Acid; Glutathione; Immunohistochemistry; Male; Primary Cell Culture; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit | 2019 |
Perampanel attenuates epileptiform phenotype in C6 glioma.
Topics: Animals; Cell Line, Tumor; Glioma; Glucose; Glutamic Acid; Male; Nitriles; Phenotype; Pyridones; Rats; Seizures; Survival Analysis; Xenograft Model Antitumor Assays | 2020 |
Potassium and glutamate transport is impaired in scar-forming tumor-associated astrocytes.
Topics: Animals; Astrocytes; Biological Transport; Brain Neoplasms; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Mice; Neuroglia; Neurons; Potassium | 2020 |
Hydrogen peroxide triggers an increase in cell surface expression of system x
Topics: Amino Acid Transport System y+; Cell Membrane; Cystine; Glioma; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Oxidative Stress | 2020 |
Does Neuronal Activity Promote Glioma Progression?
Topics: Epilepsy; Glioma; Glutamic Acid; Humans; Neurons; Signal Transduction | 2020 |
Topics: Animals; Brain; Brain Mapping; Cell Line, Tumor; Diagnostic Imaging; gamma-Aminobutyric Acid; Glioblastoma; Glioma; Glucose; Glutamic Acid; Glutamine; Glycolysis; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Staining and Labeling | 2020 |
Extracellular glutamate and IDH1
Topics: Animals; Benzeneacetamides; Brain Neoplasms; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Humans; Imidazoles; Isocitrate Dehydrogenase; Male; Mice; Oxidation-Reduction; Tumor Cells, Cultured | 2020 |
SIRT4 prevents excitotoxicity via modulating glutamate metabolism in glioma cells.
Topics: Cell Line, Tumor; Cell Survival; Excitatory Amino Acid Agonists; Glioma; Glutamic Acid; Humans; Kainic Acid; Mitochondrial Proteins; Sirtuins | 2020 |
Intratumoral retrograde microdialysis treatment of high-grade glioma with cisplatin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain; Brain Neoplasms; Cisplatin; Female; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Male; Microdialysis; Middle Aged; Neoplasm Recurrence, Local; Quality of Life; Treatment Outcome | 2020 |
MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Diamines; Glioma; Glutamic Acid; Glutarates; Glycine; Humans; Isocitrate Dehydrogenase; Mutation; Proton Magnetic Resonance Spectroscopy; Pyridines | 2020 |
Angiocentric glioma-associated seizures: The possible role of EATT2, pyruvate carboxylase and glutamine synthetase.
Topics: Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Pyruvate Carboxylase; Seizures | 2021 |
Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytes; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Multivariate Analysis; Mutation; Oligodendroglia; Seizures; Survival Analysis; Young Adult | 2021 |
γ-Glutamyl transpeptidase-activatable near-infrared nanoassembly for tumor fluorescence imaging-guided photothermal therapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Female; Fluorescence; Fluorescent Dyes; gamma-Glutamyltransferase; Glioma; Glutamic Acid; Humans; Hyperthermia, Induced; Lasers; Mice; Mice, Nude; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Photothermal Therapy; Spectroscopy, Near-Infrared; Tumor Microenvironment | 2021 |
Microglia-Derived Small Extracellular Vesicles Reduce Glioma Growth by Modifying Tumor Cell Metabolism and Enhancing Glutamate Clearance through miR-124.
Topics: Animals; Antagomirs; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Excitatory Amino Acid Transporter 2; Extracellular Vesicles; Glioma; Glutamic Acid; Interferon-gamma; Kaplan-Meier Estimate; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; MicroRNAs; Nitric Oxide; Up-Regulation | 2021 |
In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma.
Topics: Citric Acid Cycle; Computational Biology; Databases, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Glucose Transporter Type 3; Glutamic Acid; Glycolysis; Humans; Isocitrate Dehydrogenase; Lactic Acid; Metabolic Networks and Pathways; Mutation; Oxygen; Phenotype; Transcriptome | 2017 |
ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.
Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Iron; Neovascularization, Pathologic; Neurons | 2017 |
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca
Topics: Anesthetics, Intravenous; Animals; Antineoplastic Agents; Calcium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Glioma; Glutamic Acid; Glutathione; Propofol; Rats; Receptors, AMPA | 2017 |
GL261 glioma tumor cells respond to ATP with an intracellular calcium rise and glutamate release.
Topics: Adenosine Triphosphate; Calcium; Calcium Signaling; Cell Line, Tumor; Glioma; Glutamic Acid; Humans; Neoplasm Proteins; Receptors, Purinergic P2X7; Tumor Microenvironment | 2018 |
In vivo characterization of brain metabolism by
Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Brain; Brain Neoplasms; Cell Line, Tumor; Fluorodeoxyglucose F18; gamma-Aminobutyric Acid; Glioma; Glucose; Glutamic Acid; Humans; Male; Mice; Neoplasm Transplantation; Oxidation-Reduction; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy; Repressor Proteins | 2018 |
Kv1.3 activity perturbs the homeostatic properties of astrocytes in glioma.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Cell Movement; Cells, Cultured; Glioma; Glutamic Acid; Homeostasis; Kv1.3 Potassium Channel; Male; Mice; Mice, Inbred C57BL; Neurons; Potassium; Potassium Channel Blockers | 2018 |
Ratiometric delivery of two therapeutic candidates with inherently dissimilar physicochemical property through pH-sensitive core-shell nanoparticles targeting the heterogeneous tumor cells of glioma.
Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Curcumin; Doxorubicin; Drug Carriers; Drug Delivery Systems; Glioma; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Male; Micelles; Nanoparticles; Neoplastic Stem Cells; Polylysine; Polymers; Rats; Rats, Sprague-Dawley | 2018 |
Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Humans; Isocitrate Dehydrogenase; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Invasiveness; Stress, Physiological; Succinate-Semialdehyde Dehydrogenase; Transcriptome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
The Role of Metabotropic Glutamate Receptor 1 Dependent Signaling in Glioma Viability.
Topics: beta-Arrestins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Glioma; Glutamic Acid; Humans; Melanoma; Proto-Oncogene Mas; Quinolines; Receptors, Metabotropic Glutamate; RNA, Messenger; Signal Transduction | 2018 |
Pyroxazone, a new neuroprotective compound from Streptomyces sp. RAN54.
Topics: Animals; Cell Line, Tumor; Glioma; Glutamic Acid; Mice; Molecular Structure; Neuroblastoma; Neuroprotective Agents; Phthalazines; Rats; Retina; Streptomyces | 2018 |
Spatially Resolved Bioenergetic and Genetic Reprogramming Through the Brain of Rats Bearing Implanted C6 Gliomas As Detected by Multinuclear High-Resolution Magic Angle Spinning and Genomic Analysis.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Biopsy; Brain Neoplasms; Carbon Isotopes; Caudate Nucleus; Cellular Reprogramming; Female; Gene Expression Profiling; Gene Expression Regulation; Glioma; Glucose; Glutamic Acid; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Magnetic Resonance Imaging; Neoplasm Transplantation; Oxidative Phosphorylation; Rats; Rats, Wistar; Transcription Factors; Transplantation, Heterologous | 2018 |
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.
Topics: Cell Line, Tumor; Glioma; Glutamic Acid; Glutarates; Homeostasis; Humans; Isocitrate Dehydrogenase; Minor Histocompatibility Antigens; Mutation; Oxidation-Reduction; Pregnancy Proteins; Transaminases | 2018 |
Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling.
Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Dizocilpine Maleate; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Glioma; Glutamic Acid; Humans; Mice; Neoplasm Transplantation; Phosphorylation; Protein Domains; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sulfasalazine | 2018 |
GABA, glutamine, glutamate oxidation and succinic semialdehyde dehydrogenase expression in human gliomas.
Topics: Cell Proliferation; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Humans; Succinate-Semialdehyde Dehydrogenase | 2018 |
Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma.
Topics: Amino Acid Transport System X-AG; Animals; Apoptosis; Aspartic Acid; Astrocytes; Benzopyrans; Cell Line, Tumor; Cell Membrane; Excitatory Amino Acid Transporter 1; Female; Glioblastoma; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred C57BL; Protein Transport; Sodium-Potassium-Exchanging ATPase | 2019 |
An enzyme-based electrochemical biosensor probe with sensitivity to detect astrocytic versus glioma uptake of glutamate in real time in vitro.
Topics: Astrocytes; Biosensing Techniques; Electrochemical Techniques; Glioma; Glutamic Acid; Humans | 2019 |
Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging.
Topics: Adult; Brain Neoplasms; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2019 |
BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults.
Topics: Adult; Astrocytoma; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Immunohistochemistry; Male; Neoplasm Grading; Point Mutation; Proto-Oncogene Proteins B-raf; Valine | 2013 |
A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
Topics: Adult; Aspartic Acid; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Middle Aged; Mutation; Phantoms, Imaging; Protons; Young Adult | 2013 |
Increased glutamate uptake in astrocytes via propentofylline results in increased tumor cell apoptosis using the CNS-1 glioma model.
Topics: Animals; Animals, Newborn; Annexin A5; Apoptosis; Astrocytes; Cell Line, Tumor; Cell Proliferation; Cerebral Cortex; Coculture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Neuroprotective Agents; Rats; Rats, Inbred Lew; RNA, Small Interfering; Xanthines | 2013 |
Riluzole increases glutamate uptake by cultured C6 astroglial cells.
Topics: Analysis of Variance; Animals; Astrocytes; Cell Line, Tumor; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 3; Glioma; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Rats; Reactive Oxygen Species; Riluzole; S100 Calcium Binding Protein beta Subunit; Time Factors | 2013 |
Glutamate quantification in patients with supratentorial gliomas using chemical shift imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Demography; Female; Glioma; Glutamic Acid; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Phantoms, Imaging; Supratentorial Neoplasms; Young Adult | 2014 |
Accuracy of 2-hydroxyglutarate quantification by short-echo proton-MRS at 3 T: a phantom study.
Topics: Aspartic Acid; Brain; Glioma; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Mutation; Phantoms, Imaging; Proton Magnetic Resonance Spectroscopy | 2014 |
Cellular senescence induced by prolonged subculture adversely affects glutamate uptake in C6 lineage.
Topics: Animals; Aspartic Acid; Cellular Senescence; Glioma; Glutamic Acid; Rats, Wistar; Tritium; Tumor Cells, Cultured | 2014 |
Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma.
Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Male; Mutation; Radiopharmaceuticals; Rats; Rats, Nude; Transaminases | 2014 |
Glutamate/glutamine metabolism coupling between astrocytes and glioma cells: neuroprotection and inhibition of glioma growth.
Topics: Animals; Astrocytes; Cell Communication; Cell Proliferation; Cell Survival; Cells, Cultured; Glioma; Glutamic Acid; Glutamine; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness | 2014 |
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma.
Topics: Amino Acid Substitution; Animals; Brain Neoplasms; Cell Line, Tumor; Female; Gene Knockdown Techniques; Genes, p53; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Mutant Proteins; Neoplastic Stem Cells; Receptors, Glutamate | 2014 |
Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration.
Topics: Animals; Brain Neoplasms; Chemistry Techniques, Synthetic; Diagnostic Imaging; Endosomes; Fluorescent Dyes; Glioma; Glucose; Glutamic Acid; Male; Mice, Inbred BALB C; Particle Size; Peptides; Quantum Dots; Tissue Distribution; Tumor Cells, Cultured | 2014 |
Why glioma patients seize: adding more pathological GABA to the glutamate hypothesis.
Topics: Animals; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Humans; Seizures | 2014 |
Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.
Topics: Carbon Isotopes; Glioma; Glutamic Acid; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Mutation | 2015 |
CDK5 knockdown in astrocytes provide neuroprotection as a trophic source via Rac1.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Cyclin-Dependent Kinase 5; Embryo, Mammalian; Excitatory Amino Acid Agonists; Glioma; Glutamic Acid; Mutation; Nerve Tissue Proteins; Neurons; Neuroprotection; Protein Kinase Inhibitors; Purines; rac1 GTP-Binding Protein; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Roscovitine; Time Factors | 2015 |
High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
Topics: Amino Acid Transport System y+; Benzoates; Brain Neoplasms; Cell Line, Tumor; Cystine; Databases, Chemical; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Glycine; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Models, Biological; RNA, Messenger; Sulfasalazine; Time Factors | 2015 |
Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Glioma; Glutamic Acid; Large Neutral Amino Acid-Transporter 1; Liposomes; Male; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Taxoids; Vitamin E | 2016 |
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
Topics: Amino Acid Transport System y+; Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Membrane; Cell Movement; Cell Proliferation; Cystine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Reactive Oxygen Species; Sulfasalazine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Brain Neoplasms; Glioma; Glutamate Dehydrogenase; Glutamic Acid; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Mutation; Sensitivity and Specificity; Transaminases; Young Adult | 2016 |
Refined modelling of the short-T2 signal component and ensuing detection of glutamate and glutamine in short-TE, localised, (1) H MR spectra of human glioma measured at 3 T.
Topics: Adult; Algorithms; Biomarkers, Tumor; Brain Neoplasms; Computer Simulation; Female; Glioma; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Models, Biological; Models, Chemical; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2016 |
Peritumoural glutamate correlates with post-operative seizures in supratentorial gliomas.
Topics: Adult; Aged; Anticonvulsants; Chemoradiotherapy, Adjuvant; Cohort Studies; Excitatory Amino Acid Transporter 2; Female; Glioma; Glutamic Acid; Humans; Male; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Seizures; Supratentorial Neoplasms; Survival Analysis | 2016 |
Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
Topics: Animals; Brain; Brain Neoplasms; Bumetanide; Cell Line, Tumor; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; K Cl- Cotransporters; Male; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Phosphorylation; Rats; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Symporters; Tissue Culture Techniques | 2016 |
Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study.
Topics: Aged; Aged, 80 and over; Brain Neoplasms; Cytokines; Female; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Inflammation; Male; Microdialysis; Middle Aged; Radiotherapy; Statistics, Nonparametric | 2017 |
Glutamine Metabolism in Gliomas.
Topics: Brain Neoplasms; Cell Proliferation; Glioma; Glutamic Acid; Glutaminase; Glutamine; Humans; Neoplasm Invasiveness | 2016 |
BRAF V600E mutation in epilepsy-associated glioneuronal tumors: Prevalence and correlation with clinical features in a Chinese population.
Topics: Adolescent; Adult; Brain; Brain Neoplasms; Child; Child, Preschool; China; Cohort Studies; Electroencephalography; Epilepsy; Female; Glioma; Glutamic Acid; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins B-raf; Statistics as Topic; Statistics, Nonparametric; Valine; Young Adult | 2017 |
Glucose metabolites, glutamate and glycerol in malignant glioma tumours during radiotherapy.
Topics: Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Microdialysis; Radiosurgery | 2008 |
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection.
Topics: Animals; Brain Neoplasms; Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cell Survival; Cyclosporine; Dicarboxylic Acids; Drug Interactions; Enzyme Inhibitors; Estrogens; Glioma; Glutamic Acid; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Okadaic Acid; Oxidative Stress; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Stroke | 2008 |
Cerebral metabolism during air transport of patients after surgery for malignant glioma.
Topics: Air Ambulances; Brain; Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Microdialysis; Pyruvic Acid; Transportation of Patients | 2008 |
Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; DNA, Complementary; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Glutaminase; Glutamine; Humans; Isoenzymes; Microarray Analysis; Mitochondria; Polymerase Chain Reaction; RNA, Messenger; Transfection | 2009 |
The janus face of resveratrol in astroglial cells.
Topics: Actins; Analysis of Variance; Animals; Antioxidants; Astrocytes; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Hydrogen Peroxide; Nerve Growth Factors; NF-kappa B; Oxidants; Phorbol Esters; Propidium; Rats; Reactive Oxygen Species; Resveratrol; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stilbenes | 2009 |
In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Cytokines; Dexamethasone; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Intercellular Signaling Peptides and Proteins; Lactic Acid; Male; Matrix Metalloproteinase 9; Microdialysis; Middle Aged; Pyruvic Acid; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2010 |
Expression of CXCL10 in cultured cortical neurons.
Topics: Amyloid beta-Peptides; Animals; CD11b Antigen; Cells, Cultured; Cerebral Cortex; Chemokine CXCL10; Coculture Techniques; Embryo, Mammalian; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glioma; Glutamic Acid; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lipopolysaccharides; Mice; Microscopy, Immunoelectron; Neuroblastoma; Neuroglia; Neurons; Neuropeptide Y; Peptide Fragments; RNA, Messenger; Sodium Azide; Sodium Chloride; Synaptic Vesicles; Time Factors; Transfection; Vesicle-Associated Membrane Protein 2 | 2010 |
Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
Topics: Animals; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cystine; Down-Regulation; Glioma; Glutamic Acid; Humans; Mice; Rats; Receptors, AMPA; Signal Transduction; Transfection | 2011 |
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.
Topics: Blotting, Western; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Glioma; Glutamic Acid; Glutaminase; Glutarates; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Mutation; RNA Interference; Sulfides; Thiadiazoles; Time Factors | 2010 |
Impaired hippocampal synaptic plasticity in C6 glioma-bearing rats.
Topics: Animals; Body Weight; Brain Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glioma; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2011 |
[Effect of dynorphin A1-13 on C6 glioma cells swelling induced by glutamate].
Topics: Animals; Dynorphins; Glioma; Glutamic Acid; Rats; Tumor Cells, Cultured | 2001 |
Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
Topics: Aging; Amino Acid Transport System y+; Animals; Corpus Striatum; Cystine; Dopamine; Glioma; Glutamic Acid; Glutathione; Mice; Mice, Knockout; Neurodegenerative Diseases; Neurons; Oxidopamine; Substantia Nigra; Tumor Cells, Cultured | 2011 |
Riluzole-induced glial cell line-derived neurotrophic factor production is regulated through fibroblast growth factor receptor signaling in rat C6 glioma cells.
Topics: Animals; Cell Line, Tumor; CREB-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Neoplastic; Glial Cell Line-Derived Neurotrophic Factor; Glioma; Glutamic Acid; Rats; Receptors, Fibroblast Growth Factor; Riluzole; RNA, Messenger; Signal Transduction | 2011 |
Regulation of glutamate transporter GLT-1 by MAGI-1.
Topics: Animals; Astrocytes; Biotinylation; Cell Line, Tumor; Cells, Cultured; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Fluorescent Antibody Technique; Gene Expression Regulation; Glioma; Glutamic Acid; Glutathione Transferase; Guanylate Kinases; Hippocampus; Immunoprecipitation; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Membrane Proteins; Plasmids; Rats; Recombinant Fusion Proteins; RNA, Small Interfering; Transfection | 2011 |
Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells.
Topics: Animals; Calcium; Cell Line, Tumor; Dose-Response Relationship, Drug; Edema; Flavonoids; Glioma; Glucose; Glutamic Acid; Hypoxia; Intracellular Fluid; Membrane Potential, Mitochondrial; Neuroglia; Neuroprotective Agents; Quercetin; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Time Factors | 2011 |
Self-assembling dipeptide-based nontoxic vesicles as carriers for drugs and other biologically important molecules.
Topics: Antineoplastic Agents; Biocompatible Materials; Calcium; Cell Survival; Dipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Eosine I Bluish; Fluoresceins; Fluorescent Dyes; Glioma; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Molecular Structure; Solubility; Stereoisomerism; Structure-Activity Relationship; Water | 2011 |
Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity.
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; CREB-Binding Protein; Excitatory Amino Acid Transporter 2; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Membrane Proteins; Nerve Degeneration; Oncogenes; Promoter Regions, Genetic; Rats; RNA-Binding Proteins; YY1 Transcription Factor | 2011 |
Glutamate release by primary brain tumors induces epileptic activity.
Topics: Amino Acid Transport System y+; Analysis of Variance; Animals; Brain Neoplasms; Cell Transplantation; Electroencephalography; Electrophysiology; Epilepsy; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Sulfasalazine | 2011 |
Overexpression of GRP78 protects glial cells from endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum Stress; Genes, Synthetic; Glioma; Glutamic Acid; Heat-Shock Proteins; Nerve Tissue Proteins; Neurotoxins; Rats; Recombinant Fusion Proteins; Tunicamycin | 2011 |
Glioma-related seizures: glutamate is the key.
Topics: Animals; Brain Neoplasms; Epilepsy; Glioma; Glutamic Acid; Humans | 2011 |
Photodynamic therapy leads to death of C6 glioma cells partly through AMPAR.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Death; Cell Line, Tumor; Glioma; Glutamic Acid; Humans; Photochemotherapy; Receptors, AMPA | 2012 |
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Glioma; Glutamic Acid; Humans; Male; Mice; Mice, Nude; Oxaloacetic Acid; Rats; Rats, Sprague-Dawley; Temozolomide; Tumor Burden | 2012 |
Human glioma cells induce hyperexcitability in cortical networks.
Topics: Action Potentials; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Electrophysiology; Female; Glioma; Glutamic Acid; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Nerve Net; Seizures; Sulfasalazine; Tumor Cells, Cultured | 2012 |
Brain tumor-associated seizures: glutamate, transporters, and an old drug.
Topics: Female; Glioma; Glutamic Acid; Humans; Male; Seizures; Supratentorial Neoplasms; Vesicular Glutamate Transport Proteins | 2012 |
Glutamate is associated with a higher risk of seizures in patients with gliomas.
Topics: Adult; Amino Acid Transport System y+; Astrocytoma; Blotting, Western; Cohort Studies; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Female; Glioblastoma; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Retrospective Studies; Risk Factors; Seizures; Supratentorial Neoplasms; Vesicular Glutamate Transport Proteins | 2012 |
Regulation of kynurenic acid synthesis in C6 glioma cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Buffers; Calcium; Glioma; Glutamic Acid; Guanosine Diphosphate; Kynurenic Acid; Kynurenine; Leucine; Magnesium; Potassium; Rats; Receptors, Metabotropic Glutamate; Sodium; Thionucleotides; Tumor Cells, Cultured; Veratridine | 2002 |
Paving new pathways.
Topics: Antineoplastic Agents; Brain Neoplasms; Connexin 43; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Receptors, AMPA; Receptors, Glutamate | 2002 |
Human glioma cells and undifferentiated primary astrocytes that express aberrant EAAT2 mRNA inhibit normal EAAT2 protein expression and prevent cell death.
Topics: 5' Untranslated Regions; Alternative Splicing; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Apoptosis; Astrocytes; Clone Cells; Excitatory Amino Acid Transporter 2; Exons; Gene Expression Regulation; Glioma; Glutamic Acid; Humans; Neurotransmitter Uptake Inhibitors; RNA, Messenger; Synaptic Transmission; Tumor Cells, Cultured | 2002 |
Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; Animals; Cell Membrane; Cells, Cultured; Cholera Toxin; Enzyme Activation; Glioma; Glutamic Acid; Guanosine Triphosphate; Mice; Mice, Knockout; Neuroblastoma; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Retina; Signal Transduction; Superior Cervical Ganglion | 2003 |
Isoflurane enhances the expression and activity of glutamate transporter type 3 in C6 glioma cells.
Topics: Actins; Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Isoflurane; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; RNA, Messenger; Symporters; Time Factors | 2003 |
[Effects of chronic valproic acid sodium treatment and withdrawal on glutamate and glutamine release of C6 glioma cells].
Topics: Anticonvulsants; Glioma; Glutamic Acid; Glutamine; Humans; Time Factors; Tumor Cells, Cultured; Valproic Acid | 2003 |
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Discriminant Analysis; Fatty Acids; Glioma; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Patient Selection; Principal Component Analysis; Probability; Sensitivity and Specificity; Statistical Distributions | 2003 |
Volume changes and whole cell membrane currents activated during gradual osmolarity decrease in C6 glioma cells: contribution of two types of K+ channels.
Topics: Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Membrane; Cell Size; Chloride Channels; Glioma; Glutamic Acid; Membrane Potentials; Osmolar Concentration; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Taurine; Water-Electrolyte Balance | 2004 |
Inhibitory effects of 1-methyl-4-phenylpyridinium on glutamate uptake into cultured C6 glioma cells.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Transport System X-AG; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Glioma; Glutamic Acid; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2004 |
Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity.
Topics: Actin Cytoskeleton; Actins; Animals; Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Line, Tumor; Cell Surface Extensions; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Green Fluorescent Proteins; Mice; Protein Transport; Recombinant Fusion Proteins; Sucrose; Tetradecanoylphorbol Acetate | 2004 |
Promoting effects of polyunsaturated fatty acids on chromosomal giant DNA fragmentation associated with cell death induced by glutathione depletion.
Topics: Animals; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Chromosomes; DNA; DNA Fragmentation; Fatty Acids, Unsaturated; Glioma; Glutamic Acid; Glutathione; Lipid Peroxidation; Rats; Time Factors | 2004 |
Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.
Topics: Alanine; Alanine Transaminase; Brain Neoplasms; Cell Line, Tumor; Dicarboxylic Acids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Glutamyltransferase; Glioma; Gliotoxin; Glutamic Acid; Glutathione; Glycine; Humans; Immunosuppressive Agents; Indicators and Reagents; Lactic Acid; Magnetic Resonance Spectroscopy; Pyrrolidines | 2004 |
MgSO4 and lazaroid (U-83836E) partially protects glioma cells against glutamate toxicity in vitro.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Dose-Response Relationship, Drug; Drug Interactions; Glioma; Glutamic Acid; Humans; Inhibitory Concentration 50; Magnesium Sulfate; Mice; Neuroglia; Piperazines; Tetrazolium Salts; Thiazoles | 2004 |
Simultaneous detection of the release of glutamate and nitric oxide from adherently growing cells using an array of glutamate and nitric oxide selective electrodes.
Topics: Animals; Biosensing Techniques; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cells, Immobilized; Coated Materials, Biocompatible; Equipment Design; Equipment Failure Analysis; Glioma; Glutamic Acid; Microelectrodes; Nitric Oxide; Rats; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Effects of toxic doses of glutamate on Cu-Zn and Mn/superoxide dismutases activities in human glioma cell lines.
Topics: Analysis of Variance; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Glioma; Glutamic Acid; Humans; Inhibitory Concentration 50; Nervous System Neoplasms; Neurotoxins; Superoxide Dismutase | 2005 |
Pertussis toxin-sensitive modulation of glutamate transport by endothelin-1 type A receptors in glioma cells.
Topics: Amino Acid Transport System X-AG; Animals; Cell Line, Tumor; Endothelin-1; Excitatory Amino Acid Transporter 3; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Pertussis Toxin; Rats; Receptor, Endothelin A; Symporters | 2005 |
Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1.
Topics: Animals; Biological Transport; Biotinylation; Blotting, Western; Cell Line, Tumor; Cloning, Molecular; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Gene Expression; Genetic Engineering; Glioma; Glutamic Acid; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Serine; Sodium; Transfection | 2005 |
Estrogen prevents glutamate-induced apoptosis in C6 glioma cells by a receptor-mediated mechanism.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Calcium Channel Blockers; Cell Line, Tumor; Cell Survival; Estrogen Receptor alpha; Estrogens; Glioma; Glutamic Acid; In Situ Nick-End Labeling; Neuroprotective Agents; Rats | 2006 |
Serum-dependence of AMPA receptor-mediated proliferation in glioma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cattle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression; Glioma; Glutamic Acid; Humans; Quinoxalines; Rats; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Serum | 2006 |
Enhancement of serotonin- and bradykinin-evoked calcium ion dynamics in differentiated NG108-15 cells.
Topics: Acetylcholine; Animals; Bradykinin; Calcium; Cations, Divalent; Cell Differentiation; Cell Line, Tumor; Glioma; Glutamic Acid; Hybrid Cells; Intracellular Space; Mice; Neuroblastoma; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin | 2006 |
Resveratrol increases glutamate uptake and glutamine synthetase activity in C6 glioma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Rats; Resveratrol; Stilbenes | 2006 |
DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells.
Topics: Animals; Astrocytes; Brain; Brain Chemistry; Brain Neoplasms; Cells, Cultured; CpG Islands; DNA Methylation; Epigenesis, Genetic; Excitatory Amino Acid Transporter 2; Gene Silencing; Genes, Reporter; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; HeLa Cells; Humans; Neuroglia; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley | 2007 |
Increase in glutamate as a sensitive indicator of extracellular matrix integrity in peritumoral edema: a 3.0-tesla proton magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Brain Edema; Brain Neoplasms; Case-Control Studies; Extracellular Matrix; Female; Glioma; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Meningioma; Middle Aged | 2007 |
Neurosteroids alter glutamate-induced changes in neurite morphology of NG108-15 cells.
Topics: 2-Amino-5-phosphonovalerate; Cell Adhesion; Cell Line, Tumor; Excitatory Amino Acid Agonists; Glioma; Glutamic Acid; Humans; Hybrid Cells; Neurites; Neuroblastoma; Piperidines; Pregnenolone; Receptors, N-Methyl-D-Aspartate; Steroids | 2007 |
Dopamine release modifies intracellular calcium levels in tyrosine hydroxylase-transfected C6 cells.
Topics: Analysis of Variance; Animals; Benzazepines; Calcium; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dopamine; Dopamine Antagonists; Glioma; Glutamic Acid; Intracellular Space; Mice; Potassium Chloride; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Transfection; Tyrosine 3-Monooxygenase | 2007 |
Real-time detection of L-glutamate released from C6 glioma cells using a modified enzyme-luminescence method.
Topics: Animals; Biosensing Techniques; Brain; Cells, Cultured; Glioma; Glutamic Acid; Luminescence; Oxidoreductases; Potassium Chloride; Rats; Sensitivity and Specificity; Serotonin; Serotonin Agents; Stimulation, Chemical; Time Factors | 2007 |
Regulation of SULT2B1a (pregnenolone sulfotransferase) expression in rat C6 glioma cells: relevance of AMPA receptor-mediated NO signaling.
Topics: Animals; Benzothiadiazines; Cell Line, Tumor; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Isoenzymes; Neuroglia; Nitric Oxide; Pregnenolone; Quinoxalines; Rats; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfotransferases | 2008 |
Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: potential therapeutic application for treatment of gliomas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coculture Techniques; Glioma; Glutamic Acid; Microdialysis; Nerve Degeneration; Neurons; Pyrazines; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2008 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine | 2008 |
Glutamate-induced glioma cell proliferation is prevented by functional expression of the glutamate transporter GLT-1.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Excitatory Amino Acid Transporter 2; Glioma; Glutamic Acid; Rats; Transfection | 2008 |
Glutamate uptake and metabolism in C-6 glioma cells: alterations by potassium ion and dibutyryl cAMP.
Topics: Amino Acids; Animals; Biological Transport; Bucladesine; Cell Line; Chromatography, High Pressure Liquid; Glioma; Glutamates; Glutamic Acid; Kinetics; Neoplasms, Experimental; Potassium; Rats; Sodium | 1983 |
Sensitive and insensitive states of cultured glioma cells to glutamate damage.
Topics: 2-Aminoadipic Acid; Animals; Bucladesine; Cell Differentiation; Cell Line; Cells, Cultured; Flow Cytometry; Glioma; Glutamates; Glutamic Acid; Hydrocortisone; Nerve Degeneration; Rats | 1984 |
Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx.
Topics: Animals; Biological Transport; Cells, Cultured; Chlorides; Glioma; Glutamates; Glutamic Acid; Gramicidin; Kinetics; Potassium; Rats; Sodium | 1984 |
Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Cell Division; Cells, Cultured; Cocaine; DNA; Glioma; Glutamates; Glutamic Acid; L-Lactate Dehydrogenase; Leucine; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Sprague-Dawley; RNA; Thymidine; Trypan Blue; Tumor Cells, Cultured; Uridine | 1993 |
Serotonin protects C6 glioma cells from glutamate toxicity.
Topics: Animals; Antiporters; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cystine; Excitatory Amino Acid Antagonists; Glioma; Gliotoxin; Glutamates; Glutamic Acid; Glutathione; Lipid Peroxidation; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotransmitter Agents; Quisqualic Acid; Rats; Serotonin; Tumor Cells, Cultured | 1994 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine Maleate; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Ion Channels; Kainic Acid; Kinetics; Magnesium Chloride; N-Methylaspartate; Neurotoxins; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Signal Transduction; Tumor Cells, Cultured | 1994 |
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents; Cycloleucine; Embryo, Mammalian; Fetus; Glioma; Glutamic Acid; Hippocampus; Humans; Indoles; Kidney; Kinetics; Maleimides; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Processing, Post-Translational; Pyrimidines; Quinacrine; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon [1-13C]glucose incubation.
Topics: Alanine; Aspartic Acid; Carbon Isotopes; Citric Acid Cycle; Glioma; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glycogen; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Mathematics; Models, Biological; Pentose Phosphate Pathway; Perchlorates; Pyruvates; Pyruvic Acid; Tumor Cells, Cultured | 1993 |
The regulatory factors of 5-HT-stimulated Ca mobilization in C6 glioma cells.
Topics: Animals; Calcium; Cell Line; Dexamethasone; Glioma; Glutamates; Glutamic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Tumor Cells, Cultured | 1993 |
Presence of N-methyl-D-aspartate (NMDA) receptors in neuroblastoma x glioma hybrid NG108-15 cells-analysis using [45Ca2+]influx and [3H]MK-801 binding as functional measures.
Topics: Calcium Radioisotopes; Cations, Divalent; Dizocilpine Maleate; Glioma; Glutamates; Glutamic Acid; Glycine; Hybrid Cells; N-Methylaspartate; Neuroblastoma; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Spermine; Tritium | 1994 |
Humoral factors derived from glial cells protect cultured neuroblastoma cells against glutamate toxicity.
Topics: Animals; Culture Media; Glioma; Glutamates; Glutamic Acid; Neuroblastoma; Neuroglia; Neurons; Rats; Rats, Wistar; Tumor Cells, Cultured | 1994 |
Proton MR spectroscopy of experimental brain tumors in vivo.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Choline; Creatinine; Energy Metabolism; Glioma; Glutamic Acid; Inositol; Magnetic Resonance Imaging; Male; Neoplasm Transplantation; Neurilemmoma; Neuroblastoma; Phosphocreatine; Rats; Rats, Inbred F344 | 1994 |
Hypoxic effects on glutamate uptake in cultured glial cells.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Glioma; Glutamates; Glutamic Acid; Neuroglia; Tumor Cells, Cultured | 1993 |
Comparison of Na+-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1).
Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Blotting, Western; Carrier Proteins; Cerebral Cortex; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Excitatory Amino Acid Transporter 4; Excitatory Amino Acids; Female; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kinetics; Male; Oocytes; Rats; Rats, Sprague-Dawley; RNA, Complementary; Sodium; Symporters; Synaptosomes; Tritium; Xenopus laevis | 1996 |
Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.
Topics: Adenosine Triphosphate; Animals; Antiporters; Brain Neoplasms; Cell Death; Cell Nucleus; Cystine; DNA Damage; Free Radical Scavengers; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipid Peroxides; Rats; Reactive Oxygen Species; Tumor Cells, Cultured | 1996 |
Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Division; Culture Media; Glioma; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Rats; Tumor Cells, Cultured | 1996 |
Effect of 6-aminonicotinamide on metabolism of astrocytes and C6-glioma cells.
Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Brain Neoplasms; Cells, Cultured; Enzyme Inhibitors; Glioma; Glucose; Glutamic Acid; Lactic Acid; Nerve Tissue Proteins; Phosphocreatine; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1997 |
Characterization of metabotropic glutamate receptors in rat C6 glioma cells.
Topics: Animals; Brain Neoplasms; Cell Membrane; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Guanylyl Imidodiphosphate; Kinetics; Neuroprotective Agents; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Tumor Cells, Cultured | 1997 |
Swelling and damage of glial cells by lactacidosis and glutamate: effect of alpha-trinositol.
Topics: Acidosis, Lactic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Size; Cell Survival; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroglia; Tumor Cells, Cultured | 1997 |
Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Buthionine Sulfoximine; Cell Survival; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Glutathione; Kinetics; Rats; Thioctic Acid; Tumor Cells, Cultured | 1997 |
Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Catalase; Chromosomes; Deferoxamine; DNA Fragmentation; Free Radical Scavengers; Glioma; Glutamic Acid; Glutathione; Hydrogen Peroxide; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Phenanthrolines; Rats; Tumor Cells, Cultured | 1998 |
Modulation of glutamate neurotoxicity in the transformed cell culture by monoamine oxidase inhibitors, clorgyline and deprenyl.
Topics: Animals; Cell Division; Cell Line, Transformed; Cell Survival; Clorgyline; DNA, Neoplasm; Glioma; Glutamic Acid; Kinetics; L-Lactate Dehydrogenase; Monoamine Oxidase Inhibitors; Neurotoxins; Rats; Selegiline; Time Factors; Tumor Cells, Cultured | 1998 |
Novel anti-brain tumor cytotoxins specific for cancer cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Carrier Proteins; Cell Division; Cytotoxins; Exotoxins; Glioma; Glutamic Acid; Humans; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Lysine; Mutation; Plasmids; Pseudomonas aeruginosa; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-13; Recombinant Fusion Proteins; Tumor Cells, Cultured | 1998 |
Cross-talk between beta-adrenergic and metabotropic glutamate receptors in rat C6 glioma cells.
Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Enzyme Activation; Glioma; Glutamic Acid; Isoenzymes; Isoproterenol; Phospholipase C beta; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Receptors, Metabotropic Glutamate; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
Glutamate receptor activation can trigger electrical activity in human glioma cells.
Topics: Calcium; Calcium Channels; Electric Conductivity; Electrophysiology; Glioma; Glutamic Acid; Humans; Intracellular Membranes; Ion Channel Gating; Kainic Acid; Osmolar Concentration; Potassium; Receptors, Glutamate; Tumor Cells, Cultured | 1998 |
Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1.
Topics: Aspartic Acid; Astrocytes; Biological Transport; Gene Products, nef; Glioma; Glutamic Acid; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV-1; Humans; nef Gene Products, Human Immunodeficiency Virus; Peptide Fragments; Tumor Cells, Cultured | 1998 |
Lactate turnover in rat glioma measured by in vivo nuclear magnetic resonance spectroscopy.
Topics: Animals; Brain Neoplasms; Carbon Isotopes; Glioma; Glucose; Glutamic Acid; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Rats | 1998 |
Restricted photorelease of biologically active molecules near the plasma membrane.
Topics: Aniline Compounds; Animals; Calcium; Cell Membrane; Fluorescent Dyes; Glioma; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Mice; Neuroblastoma; Photolysis; Rats; Second Messenger Systems; Tumor Cells, Cultured; Xanthenes | 1998 |
[1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat.
Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain; Brain Neoplasms; Carbon Isotopes; Citric Acid Cycle; Female; Functional Laterality; gamma-Aminobutyric Acid; Glioma; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Chemical; Nerve Tissue Proteins; Rats; Rats, Wistar; Tumor Cells, Cultured | 1999 |
Glioma cells release excitotoxic concentrations of glutamate.
Topics: Animals; Benzoates; Biological Transport; Cell Line; Coculture Techniques; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Glycine; Hippocampus; Humans; Rats; Rats, Sprague-Dawley | 1999 |
Expression of neuropeptide Y by glutamatergic stimulation in rat C6 glioma cells.
Topics: Animals; Dopamine; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Haloperidol; Kainic Acid; Muscimol; Neuropeptide Y; Pentylenetetrazole; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Benzoates; Brain Neoplasms; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glucose Transporter Type 1; Glutamic Acid; Glycine; Humans; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution | 1999 |
Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study.
Topics: Amino Acids; Animals; Ascorbic Acid; Brain Chemistry; Brain Neoplasms; Extracellular Space; Female; Glioma; Glucose; Glutamic Acid; Lactic Acid; Magnetic Resonance Imaging; Microdialysis; Rats; Rats, Inbred F344; Uric Acid | 2000 |
Altered expression of glutamate transporters under hypoxic conditions in vitro.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Carrier Proteins; Cell Death; Cell Hypoxia; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hypothalamic Neoplasms; Indoles; Maleimides; Mice; Mitochondria; Nerve Tissue Proteins; Neuroglia; Neurons; Protein Kinase C; Rats; Receptors, Neurotransmitter; Recombinant Fusion Proteins; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2001 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Imaging; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine; Tumor Cells, Cultured | 2001 |
Polyunsaturated fatty acids promote 8-hydroxy-2-deoxyguanosine formation through lipid peroxidation under the glutamate-induced GSH depletion in rat glioma cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Cell Death; Chelating Agents; Deoxyguanosine; Fatty Acids, Unsaturated; Glioma; Glutamic Acid; Glutathione; Lipid Peroxidation; Rats; Tumor Cells, Cultured | 2001 |
Excitotoxic destruction facilitates brain tumor growth.
Topics: Animals; Brain Neoplasms; Glioma; Glutamic Acid; Humans; N-Methylaspartate | 2001 |
Glutamate release promotes growth of malignant gliomas.
Topics: Amino Acid Transport System X-AG; Animals; Brain Neoplasms; Carrier Proteins; Cell Division; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Luminescent Measurements; Male; Memantine; Neoplasm Transplantation; Neurons; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Symporters; Tumor Cells, Cultured | 2001 |
Internalization of metabotropic glutamate receptor in C6 cells through clathrin-coated vesicles.
Topics: Amino Acid Transport System X-AG; Animals; Arsenicals; Binding Sites; Cell Membrane; Central Nervous System; Clathrin-Coated Vesicles; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Neurons; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Sucrose; Synaptic Transmission; Tumor Cells, Cultured | 2002 |
Studies on the role of calcium in the 5-HT-stimulated release of glutamate from C6 glioma cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Enzyme Inhibitors; Glioma; Glutamic Acid; Rats; Serotonin; Tumor Cells, Cultured | 2002 |
A subdomain in the transmembrane domain is necessary for p185neu* activation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Glioma; Glutamates; Glutamic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuroblastoma; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptor, ErbB-2; Signal Transduction; Valine | 1992 |
A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion.
Topics: Animals; Biological Transport; Cell Line; Cystine; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Glutamates; Glutamic Acid; Glutathione; Kinetics; Neurotoxins; Rats; Sulfur Radioisotopes; Tritium | 1992 |
Inhibition of phosphatidylserine synthesis by glutamate, acetylcholine, thapsigargin and ionophore A23187 in glioma C6 cells.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Calcium Chloride; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Edetic Acid; Fura-2; Glioma; Glutamates; Glutamic Acid; Kinetics; Phosphatidylserines; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1992 |
Kainic acid-induced excitotoxicity in neurons and glial cells.
Topics: Action Potentials; Animals; Arachidonic Acid; Biological Transport; Brain; Calcium; Fatty Acids, Nonesterified; Gerbillinae; Glioma; Glutamates; Glutamic Acid; Kainic Acid; Male; Neuroglia; Neurons; Synaptosomes; Tumor Cells, Cultured | 1992 |
Mechanisms of glial swelling induced by glutamate.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Extracellular Space; Glioma; Glutamates; Glutamic Acid; Nervous System Neoplasms; Neuroglia; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured | 1992 |
Magnetic resonance spectroscopy and metabolism. Applications of proton and 13C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo.
Topics: Animals; Astrocytes; Brain; Brain Edema; Brain Neoplasms; Cell Line; Glioma; Glutamates; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Neuroglia; Neurotransmitter Agents; Tumor Cells, Cultured | 1991 |
Ionic concentration of shifting fluid during glutamate-induced swelling of cultured glioma cells estimated by the cytocrit technique.
Topics: Animals; Brain Neoplasms; Electrolytes; Glioma; Glutamates; Glutamic Acid; Intracellular Fluid; Osmolar Concentration; Rats; Tumor Cells, Cultured | 1990 |
Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glutamates; Glutamic Acid; Glutathione; Kinetics; Sodium; Tumor Cells, Cultured | 1990 |
Effect of glutamate analogues on brain tumor cell lines.
Topics: 2-Aminoadipic Acid; Aminobutyrates; Brain Neoplasms; Cell Division; Cell Line; Glioma; Glutamates; Glutamic Acid; Glutamine; Homocysteine; Medulloblastoma; Neuroglia; Sarcoma | 1985 |
Non-linear kinetics of glutamyl-tRNA synthesis catalyzed by high molecular weight complexes from rat brain neuronal cells but not from glial cells.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Brain; Catalysis; Cell Line; Glioma; Glutamates; Glutamic Acid; Glutamine; Kinetics; Macromolecular Substances; Mice; Molecular Weight; Neuroblastoma; Neuroglia; Rats; RNA, Transfer, Amino Acyl; Substrate Specificity; Valine | 1986 |
Specific chromosomal abnormalities characterize four established cell lines derived from malignant human gliomas.
Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Cell Line; Chromosome Aberrations; Chromosome Disorders; Female; Glial Fibrillary Acidic Protein; Glioma; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Humans; Karyotyping; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation | 1986 |