glutamic acid and Fibromyalgia

glutamic acid has been researched along with Fibromyalgia in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (27.27)29.6817
2010's18 (54.55)24.3611
2020's6 (18.18)2.80

Authors

AuthorsStudies
Cheon, GJ; Choi, SH; Jung, YH; Kang, DH; Kim, H; Lee, D; Lee, JY; Moon, JY; Seo, S1
Azparren-Angulo, M; Bordanaba-Florit, G; Cabrera, D; Falcon-Perez, JM; Garcia-Vallicrosa, C; Margolles, A; Royo, F; Ruas-Madiedo, P; Ruiz, L; Tames, H1
Bhatti, R; Garg, S; Kaur, A; Singh, AP; Singh, L1
Baeken, C; De Paepe, B; Meeus, M; Smet, J; Van Oosterwijck, J1
Andronesi, OC; Berry, MP; Edwards, RR; Ellingsen, DM; Grahl, A; Isaro, L; Lazaridou, A; Lee, J; Loggia, ML; Napadow, V; Paschali, M; Ratai, EM; Torrado-Carvajal, A; Wasan, AD; Weerasekera, A1
Ellerbrock, I; Fanton, S; Jensen, KB; Kadetoff, D; Kosek, E; Sandström, A; Schalling, M; Sitnikov, R; Tour, J1
Chu, MK; Kim, J; Lee, HS; Nam, JH1
Clauw, DJ; Harris, RE; Harte, SE; Ichesco, E; Kaplan, CM; Kochlefl, L; Larkin, TE; Mashour, GA; Mawla, I; Schrepf, A; Vatansever, D1
Clauw, DJ; Foerster, B; Hampson, J; Harris, RE; Huggins, JP; Kim, J; Napadow, V; Pauer, L; Petrou, M; Schmidt-Wilcke, T; Sundgren, PC1
Campos, MM; Klein, CP; Leite, CE; Maciel, IS; Souza, AH; Sperotto, ND1
Andrés, E; Fayed, N; Garcia-Campayo, J; Herrera-Mercadal, P; López del Hoyo, Y; Magallon, R; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla-Guedea, M; Viguera, L1
Delgado Rodrigues, RN; Goulart, LI; Prieto Peres, MF1
Bender, MA; Bikson, M; Clauw, DJ; DaSilva, AF; DeBoer, M; Foerster, BR; Harris, RE; Nascimento, TD; Rice, IC; Truong, DQ; Zubieta, JK1
Holton, K1
Christidis, N; Ernberg, M; Gerdle, B; Ghafouri, B; Kosek, E; Larsson, B; Mannerkorpi, K1
Baines, S; Osmotherly, PG; Pyke, TL1
DeSantana, JM; Sluka, KA1
Clauw, DJ; Craig, AD; Harris, RE; Kirshenbaum, E; Napadow, V; Sen, A; Sundgren, PC1
Bargalló, N; Collado, A; Gómez, E; Rami, L; Salamero, M; Valdés, M; Vázquez, M1
Gerdle, B; Larsson, B; Rosendal, L; Salvador Puigvert, L; Söderberg, K1
Andres, E; Andrés-Bergareche, H; Beltrán, J; Fayed, N; Garcia-Campayo, J; Luciano, JV; Magallón, R1
Harris, RE1
Bacci, A; Feraco, P; Leonardi, M; Malavolta, N; Passamonti, L; Pedrabissi, F; Zampogna, G1
Andres, E; Fayed, N; Garcia-Campayo, J; Moreno, S; Roca, M; Rojas, G; Serrano-Blanco, A1
Alexander, R; Kanes, S; Lee, CM; McCarthy, DJ; Pathak, S; Sanacora, G; Smith, MA1
Andrés, E; Arcega, R; Garcia-Campayo, J; López-del-Hoyo, Y; Magallon, R; Masluk, B; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla, M; Roca, M1
Geenen, R; Jacobs, JW; Janssens, EL; van Staveren, W1
Alonso, EO; Faulhaber, MH; Peres, MF; Santos, BF; Senne Soares, CA; Zukerman, E1
Cairns, BE; Svensson, P1
Alfredson, H; Bronemo, L; Crenshaw, AG; Djupsjöbacka, M; Fahlström, M; Flodgren, GM; Hellström, FB1
Acciarresi, M; Calabresi, P; Coppola, F; Floridi, A; Mancini, ML; Nardi, K; Pini, LA; Rossi, C; Sarchielli, P1
Calabresi, P; Di Filippo, M; Nardi, K; Sarchielli, P1
Clauw, DJ; Gracely, RH; Harris, RE; Hsu, M; Kim, SH; McLean, SA; Pang, Y; Petrou, M; Sundgren, PC1

Reviews

5 review(s) available for glutamic acid and Fibromyalgia

ArticleYear
Restless legs syndrome and pain disorders: what's in common?
    Current pain and headache reports, 2014, Volume: 18, Issue:11

    Topics: Calcium Channel Blockers; Diagnosis, Differential; Dopamine Agonists; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypnotics and Sedatives; Iron; Melatonin; Migraine Disorders; Pain; Polyneuropathies; Restless Legs Syndrome; Serotonin; Sleep Deprivation; Vitamin D

2014
Measuring Glutamate Levels in the Brains of Fibromyalgia Patients and a Potential Role for Glutamate in the Pathophysiology of Fibromyalgia Symptoms: A Systematic Review.
    The Clinical journal of pain, 2017, Volume: 33, Issue:10

    Topics: Brain; Fibromyalgia; Glutamic Acid; Humans; Proton Magnetic Resonance Spectroscopy

2017
Central mechanisms in the maintenance of chronic widespread noninflammatory muscle pain.
    Current pain and headache reports, 2008, Volume: 12, Issue:5

    Topics: Amides; Anesthetics, Local; Aspartic Acid; Chronic Disease; Cyclic AMP; Fatigue; Fibromyalgia; Glutamic Acid; Humans; Myofascial Pain Syndromes; Nerve Block; Nociceptors; Ropivacaine; Signal Transduction; Synaptic Transmission

2008
Hypothesis - dietary glutamate will not affect pain in fibromyalgia.
    The Journal of rheumatology, 2004, Volume: 31, Issue:4

    Topics: Diet; Fibromyalgia; Glutamic Acid; Humans; Pain

2004
Sensitization, glutamate, and the link between migraine and fibromyalgia.
    Current pain and headache reports, 2007, Volume: 11, Issue:5

    Topics: Central Nervous System; Fibromyalgia; Glutamic Acid; Humans; Migraine Disorders; Peripheral Nervous System

2007

Trials

7 trial(s) available for glutamic acid and Fibromyalgia

ArticleYear
Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients.
    Anesthesiology, 2013, Volume: 119, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics; Brain Chemistry; Chronic Pain; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Middle Aged; Neural Pathways; Pain Measurement; Pregabalin; Young Adult

2013
Changes in metabolites after treatment with memantine in fibromyalgia. A double-blind randomized controlled trial with magnetic resonance spectroscopy with a 6-month follow-up.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:11

    Topics: Adult; Aspartic Acid; Brain; Creatine; Dopamine Agents; Double-Blind Method; Female; Fibromyalgia; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memantine; Mental Status Schedule; Middle Aged; Surveys and Questionnaires; Treatment Outcome

2014
Excitatory and inhibitory brain metabolites as targets of motor cortex transcranial direct current stimulation therapy and predictors of its efficacy in fibromyalgia.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:2

    Topics: Adult; Aspartic Acid; Brain; Female; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Longitudinal Studies; Middle Aged; Motor Cortex; Pain Measurement; Proton Magnetic Resonance Spectroscopy; Transcranial Direct Current Stimulation; Treatment Outcome

2015
Increased Interstitial Concentrations of Glutamate and Pyruvate in Vastus Lateralis of Women with Fibromyalgia Syndrome Are Normalized after an Exercise Intervention - A Case-Control Study.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Case-Control Studies; Exercise Therapy; Extracellular Fluid; Female; Fibromyalgia; Glutamic Acid; Humans; Middle Aged; Pyruvic Acid; Quadriceps Muscle

2016
Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study.
    AJNR. American journal of neuroradiology, 2011, Volume: 32, Issue:9

    Topics: Adult; Aspartic Acid; Choline; Chronic Pain; Creatinine; Dipeptides; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Thalamus

2011
Evaluation of the efficacy of memantine in the treatment of fibromyalgia: study protocol for a doubled-blind randomized controlled trial with six-month follow-up.
    Trials, 2013, Jan-03, Volume: 14

    Topics: Brain; Clinical Protocols; Cognition; Double-Blind Method; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Fibromyalgia; Glutamic Acid; Health Status; Humans; Magnetic Resonance Spectroscopy; Memantine; Pain; Pain Measurement; Pain Perception; Pain Threshold; Quality of Life; Research Design; Spain; Time Factors; Treatment Outcome

2013
Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgia.
    Arthritis and rheumatism, 2008, Volume: 58, Issue:3

    Topics: Acupuncture Therapy; Adult; Biomarkers; Cerebral Cortex; Female; Fibromyalgia; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Pain; Pain Management; Severity of Illness Index; Single-Blind Method

2008

Other Studies

21 other study(ies) available for glutamic acid and Fibromyalgia

ArticleYear
Central metabolites and peripheral parameters associated neuroinflammation in fibromyalgia patients: A preliminary study.
    Medicine, 2023, Mar-31, Volume: 102, Issue:13

    Topics: Creatine; Creatinine; Fibromyalgia; Glutamic Acid; Humans; Neuroinflammatory Diseases; Receptors, Antigen, T-Cell; Tomography, X-Ray Computed

2023
Orally Administered Bifidobacterium adolescentis Diminishes Serum Glutamate Concentration in Mice.
    Microbiology spectrum, 2023, 08-17, Volume: 11, Issue:4

    Topics: Animals; Bifidobacterium; Bifidobacterium adolescentis; Feces; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Mice; Probiotics

2023
Protective Effect of Esculetin, Natural Coumarin in Mice Model of Fibromyalgia: Targeting Pro-Inflammatory Cytokines and MAO-A.
    Neurochemical research, 2020, Volume: 45, Issue:10

    Topics: Analgesics; Animals; Female; Fibromyalgia; Glutamic Acid; Glutathione; Interleukin-1beta; Lipid Peroxidation; Mice; Monoamine Oxidase; Morris Water Maze Test; Neurotransmitter Agents; Open Field Test; Reserpine; Serotonin; Tumor Necrosis Factor-alpha; Umbelliferones

2020
A capital role for the brain's insula in the diverse fibromyalgia-associated symptoms.
    Medical hypotheses, 2020, Volume: 143

    Topics: Cerebral Cortex; Fibromyalgia; Glutamic Acid; Humans; Pain; Sleep Wake Disorders

2020
3D magnetic resonance spectroscopic imaging reveals links between brain metabolites and multidimensional pain features in fibromyalgia.
    European journal of pain (London, England), 2021, Volume: 25, Issue:9

    Topics: Brain; Chronic Pain; Female; Fibromyalgia; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2021
The translocator protein gene is associated with endogenous pain modulation and the balance between glutamate and γ-aminobutyric acid in fibromyalgia and healthy subjects: a multimodal neuroimaging study.
    Pain, 2022, 02-01, Volume: 163, Issue:2

    Topics: Brain; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Healthy Volunteers; Humans; Neuroimaging; Pain; Positron-Emission Tomography; Receptors, GABA

2022
Salivary glutamate is elevated in individuals with chronic migraine.
    Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:8

    Topics: Adult; Biomarkers; Blood-Brain Barrier; Chi-Square Distribution; Chronic Pain; Female; Fibromyalgia; Glutamic Acid; Humans; Middle Aged; Migraine Disorders; Outpatients; ROC Curve; Saliva; Sensitivity and Specificity; Statistics, Nonparametric; Trigeminal Nerve

2018
Functional and neurochemical disruptions of brain hub topology in chronic pain.
    Pain, 2019, Volume: 160, Issue:4

    Topics: Adult; Brain; Brain Mapping; Case-Control Studies; Chronic Pain; Cohort Studies; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Hyperalgesia; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neurotransmitter Agents; Oxygen; Pain Measurement; Proton Magnetic Resonance Spectroscopy; Visual Analog Scale

2019
Effects of D-series resolvins on behavioral and neurochemical changes in a fibromyalgia-like model in mice.
    Neuropharmacology, 2014, Volume: 86

    Topics: Analgesics; Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; Hyperalgesia; Male; Mice; Nociceptive Pain; Pregabalin; Serotonin; Spinal Cord; Touch

2014
The role of diet in the treatment of fibromyalgia.
    Pain management, 2016, Volume: 6, Issue:4

    Topics: Fibromyalgia; Glutamic Acid; Humans

2016
Elevated insular glutamate in fibromyalgia is associated with experimental pain.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:10

    Topics: Adult; Case-Control Studies; Cerebral Cortex; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Pain; Pain Threshold

2009
Increased glutamate/glutamine compounds in the brains of patients with fibromyalgia: a magnetic resonance spectroscopy study.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:6

    Topics: Anxiety; Brain; Brain Mapping; Chi-Square Distribution; Creatine; Depression; Female; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales

2010
Increased interstitial concentrations of pyruvate and lactate in the trapezius muscle of patients with fibromyalgia: a microdialysis study.
    Journal of rehabilitation medicine, 2010, Volume: 42, Issue:7

    Topics: Adult; Cross-Sectional Studies; Extracellular Fluid; Female; Fibromyalgia; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Muscle, Skeletal; Pain Measurement; Pyruvic Acid; Surveys and Questionnaires

2010
Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate.
    Arthritis research & therapy, 2010, Volume: 12, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Cholic Acid; Cross-Sectional Studies; Diffusion Tensor Imaging; Female; Fibromyalgia; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Male; Middle Aged; Motor Cortex; Nuclear Magnetic Resonance, Biomolecular; Pain; Protons; Somatosensory Cortex

2010
Elevated excitatory neurotransmitter levels in the fibromyalgia brain.
    Arthritis research & therapy, 2010, Volume: 12, Issue:5

    Topics: Brain Chemistry; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Neurotransmitter Agents

2010
Brain dysfunction in fibromyalgia and somatization disorder using proton magnetic resonance spectroscopy: a controlled study.
    Acta psychiatrica Scandinavica, 2012, Volume: 126, Issue:2

    Topics: Adult; Brain; Case-Control Studies; Cross-Sectional Studies; Fibromyalgia; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuroimaging; Pain Measurement; Psychiatric Status Rating Scales; Somatoform Disorders

2012
Glutamate-based depression GBD.
    Medical hypotheses, 2012, Volume: 78, Issue:5

    Topics: Affect; Alzheimer Disease; Arthritis, Rheumatoid; Chronic Pain; Cognition; Coronary Artery Disease; Depression; Diabetes Complications; Fibromyalgia; Glutamic Acid; Gyrus Cinguli; Humans; Huntington Disease; Inflammation; Interferons; Models, Neurological; Models, Psychological; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Risk Factors; Stroke; Synaptic Transmission

2012
Cerebrospinal fluid glutamate levels in chronic migraine.
    Cephalalgia : an international journal of headache, 2004, Volume: 24, Issue:9

    Topics: Adult; Chromatography, High Pressure Liquid; Chronic Disease; Female; Fibromyalgia; Glutamic Acid; Humans; Male; Middle Aged; Migraine Disorders

2004
Dietary glutamate and fibromyalgia.
    The Journal of rheumatology, 2005, Volume: 32, Issue:2

    Topics: Animals; Diet; Female; Fibromyalgia; Glutamic Acid; Humans; Male; Nociceptors; Pain; Sex Factors

2005
Glutamate and prostaglandin E2 in the trapezius muscle of female subjects with chronic muscle pain and controls determined by microdialysis.
    European journal of pain (London, England), 2005, Volume: 9, Issue:5

    Topics: Adult; Chronic Disease; Dinoprostone; Extracellular Fluid; Female; Fibromyalgia; Glutamic Acid; Homeostasis; Humans; Microdialysis; Middle Aged; Muscle, Skeletal; Neck Pain; Shoulder Pain; Time Factors

2005
Increased levels of neurotrophins are not specific for chronic migraine: evidence from primary fibromyalgia syndrome.
    The journal of pain, 2007, Volume: 8, Issue:9

    Topics: Adult; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Chronic Disease; Female; Fibromyalgia; Glutamic Acid; Humans; Immunoassay; Male; Migraine Disorders; Nerve Growth Factor; Nerve Growth Factors; Predictive Value of Tests; Synaptic Transmission; Up-Regulation

2007