glutamic acid has been researched along with Disease Exacerbation in 160 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (3.75) | 18.2507 |
| 2000's | 65 (40.63) | 29.6817 |
| 2010's | 72 (45.00) | 24.3611 |
| 2020's | 17 (10.63) | 2.80 |
| Authors | Studies |
|---|---|
| Alonso, C; Anstee, QM; Arretxe, E; Brosnan, J; Dufour, JF; Gaggini, M; Gastaldelli, A; Hyötyläinen, T; Masoodi, M; Mato, JM; Millet, O; Orešič, M; Ortiz, P | 1 |
| Albrecht, J; Aldana, BI; Belfiori-Carrasco, LF; Czarnecka, AM; Obara-Michlewska, M; Pawlik, MJ; Popek, MP | 1 |
| López-Gil, X; Muñoz-Moreno, E; Simões, RV; Soria, G; Tudela, R | 1 |
| El-Daly, SM; El-Toukhy, SE; Kamel, MM; Nabih, HK | 1 |
| Arzt, M; Aziz-Bose, R; Barron, T; Chau, I; Du, PP; Geraghty, AC; Gillespie, SM; Hartmann, GG; Hui, A; Ivec, AE; Keough, MB; Kim, YS; Maleki Jahan, S; Mancusi, R; Monje, M; Mulinyawe, S; Ni, L; Ponnuswami, A; Shamardani, K; Silva-Torres, A; Spitzer, A; Su, M; Suvà, ML; Taylor, KR; Tirosh, I; Venkatesh, HS; Woo, PJ; Yalçin, B; Zhang, H | 1 |
| Blicher, JU; Eskildsen, SF; Figlewski, K; Møller, AT; Near, J; Stærmose, TG | 1 |
| Abdel Naseer, M; Fouad, AM; Hassan, A; Rabah, AM; Rashed, LA | 1 |
| Erisnor, G; Khan, A; Lee, KC; Pei, Z; Wang, HY | 1 |
| Dai, Y; Duan, DD; Qin, LX; Wei, JP; Wen, W; Wen, YQ; Xu, SJ | 1 |
| Castaño, GO; Flichman, D; Garaycoechea, M; Pirola, CJ; Sookoian, S | 1 |
| Aro, P; Bercow, M; Khrisat, T; Li, N; Liu, Z; Matsumoto, J; Peskind, E; Quinn, JF; Sheng, L; Shi, M; Soltys, D; Stewart, T; Thorland, E; Tian, C; Xie, Z; Yang, D; Zabetian, CP; Zhang, J | 1 |
| Kalita, J; Kumar, S; Kumar, V; Misra, UK | 1 |
| Fei, Z; Jing, Z; Lijuan, Y; Shuwen, H; Xi, Y; Yuefen, P | 1 |
| Andres-Mach, M; Chudzik, A; Kochalska, K; Kozioł, P; Oakden, W; Orzylowska, A; Pankowska, A; Pietura, R; Rola, R; Stanisz, GJ; Słowik, T; Łazorczyk, A | 1 |
| Luo, W; Peng, H; Wang, Y | 1 |
| Balbi, M; Bertola, N; Bonanno, G; Bonifacino, T; Ferrando, S; Frumento, G; Kumar, M; Milanese, M; Nguyen, TPN; Profumo, A; Provenzano, F; Ravera, S; Torazza, C; Viale, M; Zerbo, AR | 1 |
| Hörnschemeyer, J; Kirschstein, T; Lange, F | 1 |
| Katagi, M; Kojima, H; Nakae, Y; Ohashi, N; Okano, J; Suzuki, Y; Terashima, T | 1 |
| Foran, E; Ghosh, B; Lepore, AC; Pasinelli, P; Rosenblum, LT; Shamamandri-Markandaiah, S; Trotti, D | 1 |
| Binder, DK; Hubbard, JA | 1 |
| Bonanno, G; Bonifacino, T; Bossi, S; Cattaneo, L; Conti, F; Gallia, E; Melone, M; Milanese, M; Musante, I; Provenzano, F; Puliti, A; Usai, C | 1 |
| Haroon, E; Miller, AH | 1 |
| Abate, ML; Bugianesi, E; Buzzigoli, E; Carli, F; Cassader, M; Ciociaro, D; Della Latta, V; Gaggini, M; Gambino, R; Gastaldelli, A; Marietti, M; Rosso, C | 1 |
| Aarão, MC; Antonio, BB; Barros, V; Bittencourt, S; de Almeida, AG; Ferrazoli, E; Janisset, NRLL; Longo, BM; Macedo, CE; Mello, LE; Miranda, MF; Mundim, M; Porcionatto, M; Rodrigues, AM; Romariz, S; Valente, MF | 1 |
| Akagi, A; Iwasaki, Y; Kitamoto, T; Mimuro, M; Yamada, M; Yoshida, M | 1 |
| Geerts, H; Roberts, P; Spiros, A | 1 |
| Bushara, KO; Deelchand, DK; Eberly, LE; Emir, UE; Gomez, CM; Hutter, D; Joers, JM; Lyu, T; Öz, G | 1 |
| Chaurasia, S; Danda, D; Goel, R; Guleria, A; Jain, A; Kumar, D; Kumar, S; Kumar, U; Mishra, SK; Misra, DP; Misra, R; Zanwar, A | 1 |
| Grendar, M; Hnilicova, P; Kantorova, E; Kurca, E; Polacek, H; Zelenak, K | 1 |
| Gonzales, SS; Kraguljac, NV; Lahti, AC; Morgan, CJ; Sivaraman, S; White, DM | 1 |
| Akashi, K; Baba, E; Hirata, Y; Kamenori, S; Mitsuishi, Y; Nagano, O; Okazaki, S; Sampetrean, O; Saya, H; Shintani, S; Suina, K; Takahashi, F; Takahashi, K; Tsuchihashi, K; Yamasaki, J | 1 |
| Cheong, I; Deelchand, DK; Eberly, LE; Guliani, G; Manousakis, G; Marjańska, M; Öz, G; Walk, D | 1 |
| Faure, P; Guedin, D; Lassus, B; Mannoury la Cour, C; Millan, MJ; Naudé, J; Peyrin, JM; Von Boxberg, Y | 1 |
| Hernández-Espinosa, DR; Massieu, L; Montiel, T; Morán, J | 1 |
| Aoki, C; Dubinsky, JM; Hussey, KC; Petr, GT; Rosenberg, PA; Schultheis, LA; Sun, Y | 1 |
| Algers, J; Brown, M; Buchthal, S; Campbell, T; Cohen, RA; Daar, E; Gongvatana, A; Harezlak, J; Heaton, R; McMahon, D; Mi, D; Navia, B; Robertson, K; Schifitto, G; Singer, E; So, YT; Taylor, M; Yiannoutsos, C; Zhong, J | 1 |
| Abe, O; Aoki, Y; Gonoi, W; Inoue, H; Iwashiro, N; Kasai, K; Katsura, M; Koike, S; Natsubori, T; Sasaki, H; Takano, Y; Takao, H; Yahata, N; Yamasue, H | 1 |
| Kluijtmans, LA; Metaxas, A; Timmer, NM; van Berckel, BN; van der Stelt, I; Verbeek, MM | 1 |
| Balenko, MD; Nashed, MG; Singh, G | 1 |
| Biegon, A; Gaisler-Salomon, I; Kravitz, E | 1 |
| Bonanno, G; Bonifacino, T; Carminati, E; Conti, F; Giribaldi, F; Melone, M; Milanese, M; Musante, I; Puliti, A; Rossi, PI; Vergani, L; Voci, A | 1 |
| Hughes, RD; Kronsten, VT; Scott, TR; Shawcross, DL | 1 |
| Affolter, A; Clanachan, AS; Hersberger, M; Lemieux, H; Lou, PH; Lucchinetti, E; Warren, BE; Zaugg, M; Zhang, L | 1 |
| Centonze, D; Conrad, A; Fresegna, D; Gentile, A; Haji, N; Lutz, B; Maccarrone, M; Mandolesi, G; Musella, A; Sepman, H | 1 |
| Dreier, JP; Drenckhahn, C; Hecht, N; Pinczolits, A; Sandow, N; Scheel, M; Vajkoczy, P; Woitzik, J | 1 |
| Jia, R; Liu, B; Liu, Q; Wang, T; Yu, H | 1 |
| Deng, X; Fang, X; Li, J; Li, S; Lu, Y; Xu, R; Zhang, J; Zhou, Y | 1 |
| Acker, T; Haverkamp, T; Kimmich, C; Krämer, HH; Röcken, C; Schänzer, A; Weidner, I | 1 |
| Chen, JY; Chen, XY; Gao, F; Gao, FJ; Luo, Y; Nickerson, JM; Sun, XH; Sun, Z; Wang, Y; Wu, JH; Zhang, SH; Zhang, SJ | 1 |
| Gao, L; Pan, T; Qian, W; Shen, G; Tu, Z; Wen, H; Wu, G; Xie, S; Yang, J; Zhou, Y | 1 |
| Elgammal, FS; Elkabes, S; Korgaonkar, AA; Li, Y; Santhakumar, V; Swietek, B; Wang, J | 1 |
| Ali, MS; Heck, DE; Shakarjian, MP; Stanton, PK; Velíšek, L; Velíšková, J | 1 |
| Hala, TJ; Lepore, AC; Li, K; Poulsen, DJ; Seetharam, S; Wright, MC | 1 |
| Bedogni, F; Cobolli Gigli, C; Kilstrup-Nielsen, C; Landsberger, N; Matteoli, M; Pagani, M; Pozzi, D; Rossetti, G; Rossi, RL; Scaramuzza, L | 1 |
| Freedman, MS; Kolind, SH; Li, DK; MacMillan, EL; Oger, J; Tam, R; Traboulsee, AL; Vavasour, IM; Zhao, Y | 1 |
| Compte, A; Mayberg, HS; Ramirez-Mahaluf, JP; Roxin, A | 1 |
| Accart, N; Arigoni, M; Aurisicchio, L; Barrera, G; Bolli, E; Calogero, RA; Cavallo, F; Conti, L; Lanzardo, S; Macagno, M; Pizzimenti, S; Rooke, R; Ruiu, R | 1 |
| Cabiscol, E; Fernández-Nogales, M; Ferrer, I; Lucas, JJ; Rodríguez-Colman, MJ; Sorolla, MA; Vall-Llaura, N; Vived, C | 1 |
| Benedict, JJ; DeConti, R; Gibney, GT; Gonzalez, RJ; Kudchadkar, RR; McCardle, T; Messina, JL; Sloot, S; Smalley, KS; Sondak, VK; Turner, LM; Weber, JS; Zager, JS | 1 |
| Aleman, A; Bais, L; de Vos, A; Dlabac-De Lange, J; Knegtering, H; Liemburg, E; Opmeer, E; Pijnenborg, G; Sibeijn-Kuiper, A; van der Velde, J; Wunderink, L | 1 |
| Custodio, V; Eguiluz-Meléndez, A; González, E; Martínez-Lazcano, JC; Paz, C; Rosiles-Abonce, A; Rubio-Osornio, C; Rubio-Osornio, M; Trejo-Solís, C | 1 |
| Ahn, G; Bing, SJ; Cho, IH; Cho, J; Ha, D; Herath, KH; Jee, Y; Jo, SA; Kim, A; Kim, J; Yu, HS | 1 |
| Morton, AJ; Sawiak, SJ; Wood, NI | 1 |
| Deenen, R; Faber, C; Herrmann, AM; Klotz, L; Köhrer, K; Limmer, A; Loser, K; Luger, TA; Meuth, SG; Mykicki, N; Schwab, N; Sparwasser, T; Wachsmuth, L; Wiendl, H | 1 |
| Byrne, MD; Crescenzi, R; D'Aquilla, K; DeBrosse, C; Detre, JA; Hariharan, H; Iba, M; Krishnamoorthy, G; Lee, VM; Morales, KH; Nanga, RP; Nath, H; Reddy, R | 1 |
| Chen, XM; Deng, DP; Li, SC; Liu, YX; Pan, XH; Sun, HL; Wang, QY; Zhang, JR; Zhang, YR; Zhu, W | 1 |
| Bende, Z; Majláth, Z; Pukoli, D; Rajda, C; Vécsei, L | 1 |
| Carroll, CL; Schramm, CM; Stoltz, P; Zucker, AR | 1 |
| Graf, R; Hecht, N; Lassel, E; Schneider, UC; Schroeck, H; Vajkoczy, P; Woitzik, J | 1 |
| Bazner, S; González, RG; Halpern, EF; Kim, WK; Lee, V; Lentz, MR; Rosenberg, ES; Venna, N; Williams, K | 1 |
| Bonni, A; Hakala, P; Joensuu, T; Kopra, O; Lehesjoki, AE; Lehtinen, MK; Manninen, O; Schipper, H; Su, H; Tegelberg, S; Zukor, H | 1 |
| Ahn, YH; Choi, HJ; Kang, HJ; Kim, H; Lee, H; Paik, YK; Shin, JS; Yoo, JS; Youn, JH | 1 |
| Buriticá, E; Escobar, MI; García-Cairasco, N; Guzmán, F; Pimienta, HJ; Villamil, L | 1 |
| Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM | 1 |
| Kashihara, K; Kawada, S; Takahashi, Y | 1 |
| Ballerini, P; Biagioni, F; Buccella, S; Caciagli, F; Ciccarelli, R; Citraro, R; D'Alimonte, I; D'Auro, M; De Sarro, G; Di Iorio, P; Giuliani, P; Jiang, S; Nargi, E; Russo, E | 1 |
| Barve, RA; Malfait, AM; Melton, MA; Minnerly, JC; Shevlin, KM; Stejskal, JA; Stock, JL; Storer, CE; Tortorella, MD; Turk, JR; Weiss, DJ; Zack, MD | 1 |
| Iizuka, S; Ikarashi, Y; Imamura, S; Kanno, H; Kase, Y; Kawakami, Z; Sekiguchi, K; Takeda, S; Yamaguchi, T; Yuzurihara, M | 1 |
| Li, J; Mo, K; Scherer, SS; Yum, SW; Zhang, J | 1 |
| Moser, A; Thümen, A | 1 |
| de Diego-Adeliño, J; Gómez-Ansón, B; Morgan-Ferrando, R; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Ruscalleda, J; Vives, Y | 1 |
| Davies, NP; Davison, JE; Gissen, P; Hendriksz, CJ; Peet, AC; Sun, Y | 1 |
| Baig, I; Guttmann, RP; Levine, H; Mohmmad Abdul, H; Norris, CM | 1 |
| Gonzales, MM; Goudarzi, K; Haley, AP; Miles, SC; Tanaka, H; Tarumi, T | 1 |
| Barnham, KJ; Drew, SC; Masters, CL | 1 |
| de la Fuente-Sandoval, C; Favila, R; Graff-Guerrero, A; León-Ortiz, P; Mamo, D; Ramírez-Bermúdez, J; Stephano, S | 1 |
| Anderson, J; Jones, BW; Kondo, M; Lin, Y; Marc, RE; Rapp, K; Shaw, MV; Terasaki, H; Watt, CB; Yang, JH | 1 |
| Coral, S; Fratta, E; Maio, M; Parisi, G; Sigalotti, L | 1 |
| Oyinbo, CA | 1 |
| Lahti, AC; Reid, MA | 1 |
| Amato, MC; Bommarito, A; Carina, V; Carissimi, E; Criscimanna, A; Di Blasi, F; Galluzzo, A; Giordano, C; Latteri, MA; Modica, G; Pitrone, M; Pizzolanti, G; Richiusa, P; Rodolico, V; Spinelli, G; Zerilli, M; Zito, G | 1 |
| Barber, S; Ferraiuolo, L; Greenald, D; Heath, PR; Higginbottom, A; Kirby, J; Shaw, PJ | 1 |
| Carmichael, ST | 1 |
| Barcikowska, M; Ćwikła, JB; Gabryelewicz, T; Walecki, J | 1 |
| Hattori, K; Hori, H; Ishikawa, M; Kunugi, H; Nakata, Y; Ota, M; Sasayama, D; Sato, N; Teraishi, T | 1 |
| Del Bene, A; Inzitari, D; Lamassa, M; Palumbo, V; Piccardi, B; Saia, V | 1 |
| Dong, H; Dong, T; Dong, W; Han, Y; Song, G; Sun, H; Wang, P; Wang, X; Xie, N; Yuan, X; Yuan, Y; Zhang, A; Zhang, H; Zhang, M | 1 |
| Hernández, C; Simó, R | 1 |
| Cisneros, IE; Ghorpade, A | 1 |
| Alkan, A; Dogan, DG; Dogan, M; Kahraman, AS; Ozcan, O; Yakinci, C | 1 |
| Beaumont, V; Bradaia, A; Buisson, B; Glaser, JR; Heikkinen, T; Hendricks, SJ; Howland, D; Kontkanen, O; Lehtimäki, K; Munoz-Sanjuan, I; Park, LC; Puoliväli, J; Touller, C; Vartiainen, N; Wadel, K; Yrjänheikki, JM | 1 |
| Costa, S; Ferreira, P; Lopes, C; Medeiros, RM; Morais, A; Oliveira, J; Pinto, D; Vasconcelos, A | 1 |
| Ariano, MA; Calvert, CR; Cepeda, C; Christian, LJ; Hernández-Echeagaray, E; Hurst, RS; Jocoy, E; Levine, MS; Nguyen, OK | 1 |
| Beal McIlvain, H; Dunlop, J; Howland, DS; She, Y | 1 |
| Brinker, T; Kondziella, D; Lüdemann, W; Qu, H; Sletvold, O; Sonnewald, U | 1 |
| Freeman, P; Krentz, L; Meshul, CK; Moore, C; Robinson, S; Touchon, JC | 1 |
| Benndorf, G; Haux, D; Herzog, H; Kuechler, I; Sakowitz, O; Sarrafzadeh, A; Unterberg, A | 1 |
| Maidment, NT; Rocha, L | 1 |
| Mitani, A; Tanaka, K | 1 |
| Albrecht, J; Hilgier, W; Saran, T; Turski, WA; Urbańska, EM | 1 |
| Cortes De Oliveira, JA; Galvis-Alonso, OY; Garcia-Cairasco, N | 1 |
| Farlow, MR | 1 |
| Beales, M; Dervan, AG; McBean, GJ; Meredith, GE; Meshul, CK; Moore, C; Snyder, AK; Totterdell, S | 1 |
| Jacobsen, H; Künnecke, B; Loetscher, H; Metzger, F; Ozmen, L; Richards, JG; Steiner, G; von Kienlin, M | 1 |
| Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K | 1 |
| Chard, DT; Ingle, GT; McLean, MA; Miller, DH; Ramió-Torrentà, L; Sastre-Garriga, J; Thompson, AJ | 1 |
| Greer, JM; Pender, MP | 1 |
| Albasanz, JL; Dalfó, E; Ferrer, I; Martín, M | 1 |
| Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA | 1 |
| Souder, E | 1 |
| Blanco, M; Castellanos, M; Castillo, J; Dávalos, A; Hurtado, O; Lizasoain, I; Mallolas, J; Moro, MA; Serena, J; Sobrino, T; Vivancos, J | 1 |
| Castellanos, M; Castillo, J; Sobrino, T | 1 |
| Castellanos, M; Rodríguez-Yáñez, M; Serena, J | 1 |
| Keramat Ali, SM; Morshed, NM; Nahar, JS; Shams, M; Sobhan, MA | 1 |
| Back, SA | 1 |
| Bullock, R; Choi, S; Doppenberg, E; Khaldi, A; Reinert, M; Zauner, A | 1 |
| Abbe, P; Bahadoran, P; Bailet, O; Ballotti, R; Baron, V; Bertolotto, C; Gaggioli, C; Ortonne, JP; Robert, G; Spadafora, A; Tartare-Deckert, S | 1 |
| Kitzman, P | 1 |
| Cui, X; Feng, G; Fu, S; Gao, L; Gao, W; He, L; Li, Z; Liu, P; Qin, W; Zhang, L | 1 |
| Kanazawa, I; Kobayashi, S; Murayama, S; Sakurai, M; Takuma, H | 1 |
| Ausserer, H; Bratti, A; Lochner, P; Marth, R; Nardone, R; Tezzon, F | 1 |
| Hirokawa, M; Ito, Y; Miyauchi, A; Takano, T; Yoshida, H | 1 |
| Anthony, DC; Blamire, AM; Broom, KA; Griffin, JL; Lowe, JP; Perry, VH; Scott, H; Sibson, NR; Styles, P | 1 |
| Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J | 1 |
| Bell, KF; Bennett, DA; Cuello, AC | 1 |
| Izumi, Y; Kaji, R | 1 |
| Andreadou, E; Kapaki, E; Katsaros, N; Kokotis, P; Libitaki, G; Paraskevas, GP; Sfagos, C; Vassilopoulos, D; Zis, V | 1 |
| Bar-Shir, A; Basso, AS; Costa-Pinto, FA; Engel, Y; Frenkel, D; Gozin, M; Monsonego, A; Petrovic-Stojkovic, S; Puckett, L; Quintana, FJ; Weiner, HL | 1 |
| Alferova, VP; Barkhatova, VP; Niiazbekova, AS; Panteleeva, EA; Rebrova, OIu; Zavalishin, IA | 1 |
| Basurto-Islas, G; Binder, LI; García-Sierra, F; Guillozet-Bongaarts, AL; Luna-Muñoz, J; Mena, R | 1 |
| Cheung, M; Madhunapantula, SV; Robertson, GP; Sharma, A | 1 |
| Castillo, J; Dávalos, A; Noya, M; Serena, J | 1 |
| Akatsu, T; Kawamoto, S; Kerlin, P; Kobayashi, K; Lynch, SV; Matsunami, H; Nakagawa, S; Saheki, T; Steadman, C; Strong, RW | 1 |
| Bardgett, ME; Csernansky, JG | 1 |
| García, O; Massieu, L | 1 |
| Kempski, OS; Kossmann, T; Lenzlinger, PM; Morganti-Kosmann, MC; Stocker, R; Stover, JF | 1 |
| Fujisawa, H; Ishikawa, T; Ito, H; Maekawa, T; Suehiro, E | 1 |
| Armengou, A; Cacabelos, P; Castillo, J; Dávalos, A; Fernandez-Real, JM; Marrugat, J; Rama, R | 1 |
| Bowen, KK; Dempsey, RJ; Dogan, A; Kim, BT; Rao, VL; Rothstein, JD; Todd, KG | 1 |
| Castellanos, M; Castillo, J; Dávalos, A; Leira, R; Pumar, JM; Serena, J | 1 |
| Castillo, J; Chamorro, A; Dávalos, A; Vila, N | 1 |
| Christensen, H | 1 |
| Alavijeh, M; Böhme, GA; Boireau, A; Bordier, F; Brealey, C; Briet, D; Canton, T; Debono, MW; Jahn, G; Jimonet, P; Laville, M; Le Guern, S; Mignani, S; Pratt, J; Roberts, S; Roux, M; Stutzmann, JM; Stygall, J; Vuilhorgne, M | 1 |
| Bastone, A; Bendotti, C; Calvaresi, N; Carvelli, L; Mennini, T; Rattray, M; Rizzi, M; Suchak, SK; Tortarolo, M | 1 |
| Bensimon, G; Dib, M; Lacomblez, L; Le Forestier, N; Marouan, A; Meininger, V; Pradat, PF; Salachas, F; Spreux-Varoquaux, O | 1 |
| Castellanos, M; Castillo, J; Chamorro, A; Dávalos, A; García, MM; Leira, R; Serena, J | 1 |
| Dambinova, SA; Khounteev, GA; Skoromets, AA | 1 |
| Bolay, H; Can, A; Dalkara, T; Gürsoy-Ozdemir, Y; Onur, R; Sara, Y | 1 |
| Graf, R; Heiss, WD; Toyota, S; Valentino, M; Yoshimine, T | 1 |
| Arii, T; Imoto, K; Matsushita, K; Mori, Y; Oda, S; Rhyu, IJ; Wakamori, M | 1 |
19 review(s) available for glutamic acid and Disease Exacerbation
| Article | Year |
|---|---|
Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests.
Topics: Amino Acids; Bile Acids and Salts; Biomarkers; Disease Progression; Glutamic Acid; Glutathione; Humans; Insulin Resistance; Lipid Metabolism; Lipidomics; Metabolomics; Non-alcoholic Fatty Liver Disease; Prognosis | 2021 |
Pathway analysis of glutamate-mediated, calcium-related signaling in glioma progression.
Topics: Animals; Brain Neoplasms; Calcium; Disease Progression; Glioblastoma; Glutamic Acid; Humans; Neurons; Nitric Oxide; Signal Transduction | 2020 |
Multifaceted role of branched-chain amino acid metabolism in cancer.
Topics: Amino Acids, Branched-Chain; Animals; Carcinogenesis; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Ketoglutaric Acids; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Reactive Oxygen Species; Tumor Microenvironment | 2020 |
Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Brain; Brain Neoplasms; Brain Waves; Disease Progression; Epilepsy; Excitatory Amino Acid Antagonists; Glioblastoma; Glutamic Acid; Humans; Receptors, Ionotropic Glutamate; Receptors, Metabotropic Glutamate; Signal Transduction | 2021 |
Cancer-induced oxidative stress and pain.
Topics: Antineoplastic Agents; Antioxidants; Disease Progression; Female; Glutamic Acid; Humans; Male; Neoplasms; Nociceptive Pain; Oxidative Stress; Pain Management; Quality of Life | 2014 |
Pathophysiology of cerebral oedema in acute liver failure.
Topics: Ammonia; Animals; Astrocytes; Blood-Brain Barrier; Brain; Brain Edema; Capillary Permeability; Disease Progression; Energy Metabolism; Glutamic Acid; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Prognosis; Risk Factors | 2013 |
Excitotoxins, Mitochondrial and Redox Disturbances in Multiple Sclerosis.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Disease Models, Animal; Disease Progression; Glutamic Acid; Humans; Mitochondria; Multiple Sclerosis; Neurotoxins; Oxidation-Reduction; Oxidative Stress; Receptors, Glutamate | 2017 |
Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade.
Topics: Apoptosis; Calcium; Disease Progression; Glutamic Acid; Humans; Immune System Diseases; Lipid Peroxidation; Nerve Degeneration; Nervous System Diseases; Neuroprotective Agents; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2011 |
Brain excitability in stroke: the yin and yang of stroke progression.
Topics: Brain; Cerebral Infarction; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Learning; Memory; Recovery of Function; Signal Transduction; Stroke | 2012 |
Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments.
Topics: Anticoagulants; Blood Pressure; Brain Edema; Cerebral Infarction; Disease Progression; Encephalitis; gamma-Aminobutyric Acid; Glutamic Acid; Hemodynamics; Humans; Magnesium Sulfate; Neuroprotective Agents; Platelet Aggregation Inhibitors; Prognosis; Stroke, Lacunar; Thrombolytic Therapy | 2012 |
Neuroprotection in diabetic retinopathy.
Topics: Antibodies, Monoclonal, Humanized; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Eye Proteins; Female; Glutamic Acid; Humans; Male; Microcirculation; Nerve Growth Factors; Neuroprotective Agents; Oxidative Stress; Renin-Angiotensin System; Retinal Neurons; Serpins; Vascular Endothelial Growth Factor A | 2012 |
HIV-1, methamphetamine and astrocyte glutamate regulation: combined excitotoxic implications for neuro-AIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Amino Acid Transport System X-AG; Astrocytes; Blood-Brain Barrier; Central Nervous System Stimulants; Disease Progression; Excitatory Amino Acid Transporter 2; Female; Gene Expression Regulation; Glutamic Acid; Humans; Male; Methamphetamine; Neurotransmitter Agents; Substance Abuse, Intravenous | 2012 |
NMDA receptor antagonists. A new therapeutic approach for Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Disease Progression; Donepezil; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Indans; Memantine; Piperidines; Receptors, N-Methyl-D-Aspartate | 2004 |
Neuropathology in Alzheimer's disease: target of pharmacotherapy.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholinesterase Inhibitors; Disease Progression; Estrogens; Glutamic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; N-Methylaspartate; Neurofibrillary Tangles; Neuropharmacology; Neurotransmitter Agents | 2005 |
Evolving paradigms for neuroprotection: molecular identification of ischemic penumbra.
Topics: Animals; Brain; Brain Ischemia; Calcium; Disease Progression; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Genes, Immediate-Early; Glutamic Acid; Heat-Shock Proteins; Humans; Neuroprotective Agents; Nuclear Receptor Subfamily 4, Group A, Member 1; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Stroke; Transcription Factors | 2006 |
Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms.
Topics: Adenosine; Cytokines; Disease Progression; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Leukomalacia, Periventricular; Magnetic Resonance Imaging; Obstetric Labor Complications; Oligodendroglia; Pregnancy; Pregnancy Complications | 2006 |
[Clinical trials of ultra-high-dose methylcobalamin in ALS].
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Progression; Double-Blind Method; Glutamic Acid; Humans; Pulse Therapy, Drug; Randomized Controlled Trials as Topic; Rats; Time Factors; Vitamin B 12 | 2007 |
Limbic-cortical neuronal damage and the pathophysiology of schizophrenia.
Topics: Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Drug Resistance; Frontal Lobe; Glutamic Acid; Hippocampus; Humans; Limbic System; Models, Neurological; Neural Pathways; Schizophrenia; Severity of Illness Index | 1998 |
The role of excitotoxicity and metabolic failure in the pathogenesis of neurological disorders.
Topics: Acute Disease; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Disease Progression; Glutamic Acid; Metabolic Diseases; Nervous System Diseases; Neurotoxins | 1998 |
4 trial(s) available for glutamic acid and Disease Exacerbation
| Article | Year |
|---|---|
Acute focal neurological deficits in aneurysmal subarachnoid hemorrhage: relation of clinical course, CT findings, and metabolite abnormalities monitored with bedside microdialysis.
Topics: Acute Disease; Biomarkers; Brain; Cerebral Angiography; Demography; Disease Progression; Female; Glucose; Glutamic Acid; Glycerol; Humans; Lactose; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Nervous System Diseases; Paresis; Predictive Value of Tests; Prospective Studies; Subarachnoid Hemorrhage; Tomography, X-Ray Computed; Vasospasm, Intracranial | 2003 |
Metabolite changes in normal-appearing gray and white matter are linked with disability in early primary progressive multiple sclerosis.
Topics: Adult; Age of Onset; Aged; Aspartic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Choline; Disability Evaluation; Disease Progression; Female; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Nerve Fibers, Myelinated; Neurons; Neuropil; Phosphocreatine; Predictive Value of Tests; Reference Values; Statistics as Topic | 2005 |
Body iron stores and early neurologic deterioration in acute cerebral infarction.
Topics: Acute Disease; Aged; Brain; Brain Ischemia; Cerebral Infarction; Disease Progression; Double-Blind Method; Female; Ferritins; Glutamic Acid; Humans; Iron; Logistic Models; Male; Odds Ratio; Predictive Value of Tests; Sensitivity and Specificity; Tomography, X-Ray Computed | 2000 |
Neurological deterioration in acute lacunar infarctions: the role of excitatory and inhibitory neurotransmitters.
Topics: Acute Disease; Aged; Brain Infarction; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurotransmitter Agents; Predictive Value of Tests; Prognosis; Sensitivity and Specificity; Severity of Illness Index; Tomography, X-Ray Computed | 2001 |
137 other study(ies) available for glutamic acid and Disease Exacerbation
| Article | Year |
|---|---|
Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose.
Topics: Animals; Brain; Disease Progression; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Lithium; Male; Methionine Sulfoximine; Pilocarpine; Rats; Rats, Sprague-Dawley; Secretory Pathway; Seizures | 2021 |
Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Choline; Creatine; Disease Models, Animal; Disease Progression; Glutamic Acid; Inositol; Rats; Taurine | 2022 |
The diagnostic significance of circulating miRNAs and metabolite profiling in early prediction of breast cancer in Egyptian women.
Topics: Biomarkers, Tumor; Breast Neoplasms; Circulating MicroRNA; Disease Progression; Egypt; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; MicroRNAs; Tandem Mass Spectrometry | 2023 |
Glioma synapses recruit mechanisms of adaptive plasticity.
Topics: Adaptation, Physiological; Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Proliferation; Child; Disease Progression; Glioma; Glutamic Acid; Humans; Neuronal Plasticity; Neurons; Optogenetics; Receptor, trkB; Receptors, AMPA; Signal Transduction; Synapses; Tumor Microenvironment | 2023 |
Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T.
Topics: Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Atrophy; Choline; Creatine; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gray Matter; Hand Strength; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Occipital Lobe; Pilot Projects; Severity of Illness Index; Single-Blind Method | 2019 |
Glutamate and Nitric Oxide as biomarkers for disease activity in patients with multiple sclerosis.
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Disease Progression; Female; Glutamic Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nitric Oxide; Recurrence; Young Adult | 2020 |
Drinking water temperature affects cognitive function and progression of Alzheimer's disease in a mouse model.
Topics: Alzheimer Disease; Animals; Brain; Cognition; Cold Temperature; Disease Progression; Drinking Water; gamma-Aminobutyric Acid; Glutamic Acid; Insulin; Male; Mice, Inbred C57BL; Mice, Transgenic; Morris Water Maze Test; Neurotransmitter Agents; Open Field Test; Signal Transduction | 2021 |
Liver mitochondrial DNA damage and genetic variability of Cytochrome b - a key component of the respirasome - drive the severity of fatty liver disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aldehydes; Amino Acids, Branched-Chain; Cytochromes b; Disease Progression; DNA Damage; DNA, Mitochondrial; Glutamic Acid; Glutarates; Humans; Lipid Peroxidation; Liver; Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Phosphorylation; Oxidative Stress; Severity of Illness Index; Transcriptome | 2021 |
Erythrocytic α-synuclein contained in microvesicles regulates astrocytic glutamate homeostasis: a new perspective on Parkinson's disease pathogenesis.
Topics: alpha-Synuclein; Animals; Astrocytes; Cell-Derived Microparticles; Disease Progression; Erythrocytes; Glutamic Acid; Homeostasis; Humans; Mice; Parkinson Disease | 2020 |
Movement Disorder in Wilson Disease: Correlation with MRI and Biomarkers of Cell Injury.
Topics: Adolescent; Adult; Age of Onset; Biomarkers; Child; Cytokines; Disease Progression; Dyskinesias; Female; Glutamic Acid; Glutathione; Hepatolenticular Degeneration; Humans; Magnetic Resonance Imaging; Male; Malondialdehyde; Movement Disorders; Neuroimaging; Oxidative Stress; Severity of Illness Index; Thiobarbituric Acid Reactive Substances; Young Adult | 2021 |
Molecular characteristics associated with ferroptosis in hepatocellular carcinoma progression.
Topics: Activating Transcription Factor 3; Alanine; Carcinoma, Hepatocellular; Disease Progression; Ferroptosis; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Glutamic Acid; Heat-Shock Proteins; Humans; Liver Neoplasms; MAP Kinase Signaling System; Molecular Chaperones; NAD; Survival Rate | 2021 |
Dietary supplementation with Lactobacillus rhamnosus JB-1 restores brain neurochemical balance and mitigates the progression of mood disorder in a rat model of chronic unpredictable mild stress.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Choline; Depressive Disorder; Dietary Supplements; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Lacticaseibacillus rhamnosus; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Stress, Psychological | 2020 |
Blocking glutamate mGlu
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Female; Glutamic Acid; Male; Mice; Mice, Transgenic; Receptor, Metabotropic Glutamate 5; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1 | 2021 |
GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Bone Marrow Cells; Bone Marrow Transplantation; Cell Survival; Cytokines; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Gene Transfer Techniques; Genetic Therapy; Gliosis; Glutamic Acid; Lentivirus; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Motor Activity; Motor Neurons; Muscular Atrophy; Nerve Degeneration; RNA, Messenger; Spinal Cord; Superoxide Dismutase-1; Survival Analysis | 2021 |
Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Caspase 3; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Glutamic Acid; Intranuclear Inclusion Bodies; Mice; Motor Neurons; Mutation; Superoxide Dismutase | 2017 |
Targeting glutamate transporter-1 in neurological diseases.
Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Disease Progression; Epilepsy; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamic Acid; Homeostasis; Humans; Mice; Models, Biological; Nervous System Diseases; Neurodegenerative Diseases | 2017 |
In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cell Death; Cell Survival; Disease Models, Animal; Disease Progression; Female; Glutamic Acid; Humans; Male; Mice, Transgenic; Microglia; Motor Neurons; Motor Skills; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Sex Factors; Spinal Cord; Superoxide Dismutase-1 | 2017 |
Inflammation Effects on Glutamate as a Pathway to Neuroprogression in Mood Disorders.
Topics: Animals; Brain; Disease Progression; Glutamic Acid; Humans; Inflammation; Mood Disorders; Neurotransmitter Agents; Oxidative Stress | 2017 |
Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.
Topics: Adult; Age Factors; Amino Acids; Biomarkers; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Tyrosine | 2018 |
Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy.
Topics: Action Potentials; Animals; Autonomic Nervous System; Biperiden; Chronic Disease; Cytokines; Disease Models, Animal; Disease Progression; Epilepsy; Exploratory Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Rats, Wistar | 2017 |
Pathological progression of genetic Creutzfeldt-Jakob disease with a PrP V180I mutation.
Topics: Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; Gliosis; Glutamic Acid; Humans; Isoleucine; Methionine; Middle Aged; Mutation; Prion Proteins; Vacuoles; Valine | 2018 |
Impact of amyloid-beta changes on cognitive outcomes in Alzheimer's disease: analysis of clinical trials using a quantitative systems pharmacology model.
Topics: Algorithms; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Clinical Trials as Topic; Cognition; Cognitive Dysfunction; Computer Simulation; Disease Progression; Glutamic Acid; Humans; Models, Neurological; Muscarinic Antagonists; Peptide Fragments; Scopolamine; Synaptic Transmission; Treatment Outcome | 2018 |
Neurochemical abnormalities in premanifest and early spinocerebellar ataxias.
Topics: Activities of Daily Living; Adult; Aged; Aspartic Acid; Ataxins; Brain; Brain Diseases, Metabolic; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Spinocerebellar Ataxias; Young Adult | 2018 |
NMR-Based Serum Metabolomics of Patients with Takayasu Arteritis: Relationship with Disease Activity.
Topics: Adult; Area Under Curve; Biomarkers; Blood Sedimentation; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Male; Metabolomics; Neoplasm Proteins; Principal Component Analysis; Severity of Illness Index; Takayasu Arteritis | 2018 |
Increased glutamate and deep brain atrophy can predict the severity of multiple sclerosis.
Topics: Adult; Aspartic Acid; Atrophy; Disease Progression; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Predictive Value of Tests; Severity of Illness Index; Thalamus; Young Adult | 2019 |
Neurometabolic abnormalities in the associative striatum in antipsychotic-naïve first episode psychosis patients.
Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Corpus Striatum; Disease Progression; Dopamine; Female; Glutamic Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult | 2018 |
Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling.
Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Dizocilpine Maleate; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Glioma; Glutamic Acid; Humans; Mice; Neoplasm Transplantation; Phosphorylation; Protein Domains; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sulfasalazine | 2018 |
Neurochemical correlates of functional decline in amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Longitudinal Studies; Male; Middle Aged; Motor Cortex; Motor Neurons; Pons; Prognosis; Proton Magnetic Resonance Spectroscopy; Upper Extremity | 2019 |
Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips.
Topics: Animals; Calcium; Calcium Signaling; Cerebral Cortex; Corpus Striatum; Disease Progression; Dopamine; Glutamic Acid; In Vitro Techniques; Mice; Microfluidics; Molecular Imaging; Neural Pathways; Neurons; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2018 |
Role of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage.
Topics: Animals; Corpus Striatum; Disease Progression; Glutamic Acid; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2 | 2019 |
Decreased expression of GLT-1 in the R6/2 model of Huntington's disease does not worsen disease progression.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Glutamic Acid; Huntington Disease; Mice; Mice, Transgenic; Presynaptic Terminals | 2013 |
Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Choline; Cognition; Disease Progression; Female; Glutamic Acid; HIV; Humans; Inositol; Male; Middle Aged; Neuropsychological Tests | 2013 |
Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Chronic Disease; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prodromal Symptoms; Psychotic Disorders; Risk; Schizophrenia; Young Adult | 2014 |
Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoradiography; Cerebellum; Cerebral Cortex; Disease Models, Animal; Disease Progression; Glutamic Acid; Glycine; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, N-Methyl-D-Aspartate; Vesicular Glutamate Transport Protein 1 | 2014 |
Hippocampal glutamate NMDA receptor loss tracks progression in Alzheimer's disease: quantitative autoradiography in postmortem human brain.
Topics: Alzheimer Disease; Autoradiography; Disease Progression; Female; Glutamic Acid; Hippocampus; Humans; Male; Receptors, N-Methyl-D-Aspartate | 2013 |
Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Catalase; Disease Progression; Excitatory Amino Acid Transporter 2; Glutamic Acid; Metallothionein; Mice; Mice, Transgenic; Microglia; Mitochondria; Motor Activity; Motor Neurons; Point Mutation; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; RNA, Messenger; Severity of Illness Index; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Survival Analysis | 2014 |
Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.
Topics: Aconitate Hydratase; Animals; Carnitine; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disease Progression; Energy Metabolism; Fatty Acids; Fructose; Glutamic Acid; Glycolysis; Insulin Resistance; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Phosphorylation; Prediabetic State; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2014 |
Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis.
Topics: Animals; Corpus Striatum; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Presynaptic Terminals; Receptor, Cannabinoid, CB1; Synaptic Transmission; Time Factors | 2014 |
Excitotoxicity and metabolic changes in association with infarct progression.
Topics: Adult; Aged; Aged, 80 and over; Brain; Cerebral Infarction; Disease Progression; Female; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Neurotoxins; Pyruvic Acid; Stroke | 2014 |
Interaction between interleukin-1 beta and angiotensin II receptor 1 in hypothalamic paraventricular nucleus contributes to progression of heart failure.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Heart Failure; Interleukin-1beta; Losartan; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2014 |
The possible mechanism of Parkinson's disease progressive damage and the preventive effect of GM1 in the rat model induced by 6-hydroxydopamine.
Topics: Animals; bcl-2-Associated X Protein; Brain; Calcium; Calmodulin; Disease Progression; G(M1) Ganglioside; Glutamic Acid; Infusions, Parenteral; Male; Malondialdehyde; Mitochondria; Neuroprotective Agents; Nitric Oxide Synthase Type I; Oxidopamine; Parkinsonian Disorders; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Trace Elements | 2014 |
A woman with a rare p.Glu74Gly transthyretin mutation presenting exclusively with a rapidly progressive neuropathy: a case report.
Topics: Adult; Amyloid Neuropathies, Familial; Benzoxazoles; Disease Progression; Fatal Outcome; Female; Genetic Linkage; Glutamic Acid; Glycine; Humans; Liver Transplantation; Mutation, Missense; Pedigree; Prealbumin | 2014 |
Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucoma.
Topics: Animals; Apoptosis; Axons; Cell Survival; Disease Models, Animal; Disease Progression; DNA Damage; DNA Repair; DNA, Mitochondrial; Glaucoma; Glutamic Acid; Intraocular Pressure; Male; Mitochondria; Mutation; Optic Nerve; Rats, Wistar; Retinal Ganglion Cells; Time Factors | 2015 |
Elevated expression of glutaminase confers glucose utilization via glutaminolysis in prostate cancer.
Topics: Adenosine Triphosphate; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Disease Progression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucose; Glutamic Acid; Glutaminase; Glutamine; Glycolysis; Humans; Immunohistochemistry; Male; Neoplasm Invasiveness; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; RNA Interference | 2015 |
Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury.
Topics: Animals; Brain Concussion; Dentate Gyrus; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neurons; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials; Time Factors; Tissue Culture Techniques; Toll-Like Receptor 4 | 2015 |
Combined diazepam and MK-801 therapy provides synergistic protection from tetramethylenedisulfotetramine-induced tonic-clonic seizures and lethality in mice.
Topics: Animals; Anticonvulsants; Brain Waves; Bridged-Ring Compounds; Central Nervous System; Diazepam; Disease Progression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroencephalography; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Time Factors; Video Recording | 2015 |
GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cervical Cord; Dependovirus; Diaphragm; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Female; Genetic Vectors; Glutamic Acid; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Superoxide Dismutase | 2015 |
Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.
Topics: Animals; Calcium; Cell Movement; Cells, Cultured; Cerebral Cortex; Disease Progression; Electric Stimulation; Fluorescent Antibody Technique; Glutamic Acid; Methyl-CpG-Binding Protein 2; Mice, Knockout; Neurons; Rett Syndrome; Time Factors; Transcription, Genetic; Voltage-Sensitive Dye Imaging | 2016 |
Progressive multiple sclerosis exhibits decreasing glutamate and glutamine over two years.
Topics: Adult; Aged; Biomarkers; Disease Progression; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Time Factors | 2016 |
A Computational Model of Major Depression: the Role of Glutamate Dysfunction on Cingulo-Frontal Network Dynamics.
Topics: Action Potentials; Brain Waves; Cognition; Computer Simulation; Deep Brain Stimulation; Depressive Disorder, Major; Disease Progression; Emotions; Frontal Lobe; Glutamic Acid; Gyrus Cinguli; Humans; Memory, Short-Term; Models, Neurological; Neural Pathways; Neurons; Selective Serotonin Reuptake Inhibitors; Serotonin | 2017 |
Immunotargeting of Antigen xCT Attenuates Stem-like Cell Behavior and Metastatic Progression in Breast Cancer.
Topics: Amino Acid Transport Systems; Animals; Antigens, Neoplasm; Breast Neoplasms; Cancer Vaccines; Cell Line, Tumor; Cystine; Disease Progression; Female; Glutamic Acid; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplastic Stem Cells; NIH 3T3 Cells; Up-Regulation; Vaccines, DNA; Xenograft Model Antitumor Assays | 2016 |
Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice.
Topics: Adult; Aged; Animals; Cerebral Cortex; Corpus Striatum; Cystathionine; Disease Models, Animal; Disease Progression; Female; Glutamic Acid; Humans; Huntington Disease; Male; Mice; Mice, Transgenic; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Young Adult | 2016 |
BRAF inhibition for advanced locoregional BRAF V600E mutant melanoma: a potential neoadjuvant strategy.
Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Follow-Up Studies; Glutamic Acid; Humans; Imidazoles; Indoles; Male; Melanoma; Middle Aged; Molecular Targeted Therapy; Mutation, Missense; Neoadjuvant Therapy; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Retrospective Studies; Skin Neoplasms; Sulfonamides; Treatment Outcome; Valine; Vemurafenib | 2016 |
Prefrontal NAA and Glx Levels in Different Stages of Psychotic Disorders: a 3T 1H-MRS Study.
Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Male; Middle Aged; Neurotransmitter Agents; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Regression Analysis; Risk; Severity of Illness Index; Time Factors | 2016 |
Decreased Expression of Sox-1 in Cerebellum of Rat with Generalized Seizures Induced by Kindling Model.
Topics: Amygdala; Animals; Blotting, Western; Cerebellum; Chromatography, High Pressure Liquid; Disease Models, Animal; Disease Progression; Electric Stimulation; Epilepsy, Generalized; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Kindling, Neurologic; Neuroglia; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; Seizures; SOXB1 Transcription Factors | 2016 |
Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
Topics: Amino Acids; Animals; Astrocytes; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Protease Inhibitors; Rats, Inbred Lew; Receptors, Metabotropic Glutamate; Spinal Cord; Th1 Cells; Xanthenes | 2016 |
Similar Progression of Morphological and Metabolic Phenotype in R6/2 Mice with Different CAG Repeats Revealed by In Vivo Magnetic Resonance Imaging and Spectroscopy.
Topics: Animals; Aspartic Acid; Brain; Disease Models, Animal; Disease Progression; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Trinucleotide Repeats | 2016 |
Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.
Topics: Action Potentials; alpha-MSH; Animals; Blood-Brain Barrier; Bone Marrow Cells; Cell Proliferation; Central Nervous System; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Gene Expression Profiling; Glutamic Acid; Hippocampus; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Protein Binding; Receptor, Melanocortin, Type 1; T-Lymphocytes, Regulatory | 2016 |
Longitudinal imaging reveals subhippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Disease Progression; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; Longitudinal Studies; Mice, Transgenic; Nerve Tissue Proteins; Neuroglia; Organ Size; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptophysin; tau Proteins; Tauopathies; Vesicular Glutamate Transport Protein 1 | 2017 |
Altered glutamate metabolism contributes to antiepileptogenic effects in the progression from focal seizure to generalized seizure by low-frequency stimulation in the ventral hippocampus.
Topics: Animals; Cerebral Cortex; Dentate Gyrus; Disease Progression; Electric Stimulation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Hippocampus; Kindling, Neurologic; Male; Rats; Rats, Sprague-Dawley; Seizures | 2017 |
Beta2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations.
Topics: Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; Child; Child, Preschool; Disease Progression; Female; Genotype; Glutamic Acid; Glutamine; Glycine; Humans; Length of Stay; Male; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-2; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2009 |
Ischemia independent lesion evolution during focal stroke in rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Disease Progression; Glutamic Acid; Heart Rate; Hemodynamics; Infarction, Anterior Cerebral Artery; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection.
Topics: Adult; AIDS Dementia Complex; Aspartic Acid; Biomarkers; Brain; CD4-CD8 Ratio; Disease Progression; Early Diagnosis; Frontal Lobe; Glutamic Acid; HIV Seropositivity; Humans; Immunophenotyping; Magnetic Resonance Spectroscopy; Middle Aged; Neurons; T-Lymphocytes | 2009 |
Cystatin B deficiency sensitizes neurons to oxidative stress in progressive myoclonus epilepsy, EPM1.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cathepsin B; Cell Death; Cells, Cultured; Cerebellum; Cystathionine gamma-Lyase; Disease Models, Animal; Disease Progression; Galactosides; Gene Expression Regulation, Enzymologic; Glutamic Acid; Green Fluorescent Proteins; Hydrogen Peroxide; Mice; Mice, Knockout; Neurons; Oxidants; Oxidation-Reduction; Oxidative Stress; Rats; RNA, Small Interfering; Transfection; Unverricht-Lundborg Syndrome | 2009 |
Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers.
Topics: Adenocarcinoma; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Nucleus; Colonic Neoplasms; Cytoplasm; Disease Progression; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glutamic Acid; HMGB1 Protein; Humans; Intestinal Mucosa; Mutation; Neoplasm Invasiveness; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Serine; Signal Transduction; Transfection | 2009 |
Changes in calcium-binding protein expression in human cortical contusion tissue.
Topics: Adolescent; Adult; Aged; Antigens, Nuclear; Biomarkers; Brain Injuries; Calbindin 2; Calbindins; Calcium-Binding Proteins; Cerebral Cortex; Disease Progression; Female; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Immunohistochemistry; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Tissue Proteins; Neurons; Parvalbumins; S100 Calcium Binding Protein G; Young Adult | 2009 |
In vivo glutamate decline associated with kainic acid-induced status epilepticus.
Topics: Analysis of Variance; Animals; Aspartic Acid; Disease Progression; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; Kainic Acid; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Organ Size; Rats; Rats, Wistar; Seizures; Status Epilepticus; Time Factors | 2009 |
Autoantibodies to glutamate receptor GluRepsilon2 in a patient with limbic encephalitis associated with relapsing polychondritis.
Topics: Amygdala; Anti-Inflammatory Agents; Anticonvulsants; Atrophy; Autoantibodies; Biomarkers; Brain; Cartilage; Disease Progression; Glutamic Acid; Hippocampus; Humans; Limbic Encephalitis; Limbic System; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Nerve Degeneration; Phenytoin; Polychondritis, Relapsing; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission; Temporal Lobe; Treatment Outcome | 2009 |
Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease.
Topics: Adenosine; Age Factors; Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Disease Progression; Electroencephalography; Epilepsy, Absence; Glutamic Acid; Immunohistochemistry; Male; MAP Kinase Signaling System; Microinjections; Phenethylamines; Pyrimidines; Rats; Receptor, Adenosine A2A; Somatosensory Cortex; Thalamus; Triazoles | 2009 |
Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8).
Topics: ADAM Proteins; Animals; Antigens, CD; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Catalysis; Cells, Cultured; Collagen Type II; Cytokines; Disease Progression; Gene Expression Profiling; Glutamic Acid; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Organ Size; Point Mutation; Severity of Illness Index | 2009 |
Effects of yokukansan, a traditional Japanese medicine, on memory disturbance and behavioral and psychological symptoms of dementia in thiamine-deficient rats.
Topics: Aggression; Animals; Anxiety; Astrocytes; Behavior, Animal; Brain; Dementia; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fungi; Glutamic Acid; Magnoliopsida; Male; Medicine, East Asian Traditional; Medicine, Kampo; Memory Disorders; Neurons; Phytotherapy; Rats; Rats, Wistar; Social Behavior; Thiamine Deficiency | 2009 |
A novel recessive Nefl mutation causes a severe, early-onset axonal neuropathy.
Topics: Adolescent; Age of Onset; Animals; Axons; Child; Child, Preschool; Disease Models, Animal; Disease Progression; DNA Mutational Analysis; Family Health; Female; Follow-Up Studies; Genetic Predisposition to Disease; Glutamic Acid; Humans; Infant; Male; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mutagenesis, Site-Directed; Mutation; Neural Conduction; Neurofilament Proteins; Peripheral Nervous System Diseases; Severity of Illness Index; Sural Nerve; Young Adult | 2009 |
An uncommon paraneoplastic Ri-positive opsoclonus-myoclonus-like syndrome and stiff-person syndrome with elevated glutamate/GABA ratio in the cerebrospinal fluid after breast cancer.
Topics: Antigens, Neoplasm; Autoantibodies; Breast Neoplasms; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Middle Aged; Nerve Tissue Proteins; Neuro-Oncological Ventral Antigen; Opsoclonus-Myoclonus Syndrome; RNA-Binding Proteins; Stiff-Person Syndrome | 2010 |
Ventromedial prefrontal spectroscopic abnormalities over the course of depression: a comparison among first episode, remitted recurrent and chronic patients.
Topics: Adult; Age of Onset; Aspartic Acid; Choline; Chronic Disease; Depressive Disorder, Major; Disease Progression; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Prefrontal Cortex | 2011 |
Quantitative in vivo brain magnetic resonance spectroscopic monitoring of neurological involvement in mucopolysaccharidosis type II (Hunter Syndrome).
Topics: Adolescent; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Case-Control Studies; Child; Child, Preschool; Choline; Disease Progression; Enzyme Replacement Therapy; Glutamic Acid; Humans; Iduronate Sulfatase; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mucopolysaccharidosis II; Predictive Value of Tests; Treatment Outcome | 2010 |
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.
Topics: Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Calpain; Case-Control Studies; Cell Culture Techniques; Cell Fractionation; Cognition Disorders; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Female; Glutamic Acid; Hippocampus; Humans; Male; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Retrospective Studies; Signal Transduction | 2011 |
Elevated cerebral glutamate and myo-inositol levels in cognitively normal middle-aged adults with metabolic syndrome.
Topics: Adult; Brain Chemistry; Cognition Disorders; Disease Progression; Female; Glutamic Acid; Humans; Inositol; Intelligence Tests; Language; Magnetic Resonance Spectroscopy; Male; Memory; Metabolic Syndrome; Middle Aged; Neuropsychological Tests; Periaqueductal Gray; Psychomotor Performance; Space Perception; Visual Perception; Wechsler Scales | 2010 |
Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Copper; Disease Progression; Electron Spin Resonance Spectroscopy; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Ligands; Mice; Mutation; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Stereoisomerism | 2010 |
Higher levels of glutamate in the associative-striatum of subjects with prodromal symptoms of schizophrenia and patients with first-episode psychosis.
Topics: Adolescent; Adult; Age of Onset; Caudate Nucleus; Disease Progression; Female; Glutamic Acid; Humans; Male; Psychotic Disorders; Risk Factors; Schizophrenia; Up-Regulation; Young Adult | 2011 |
Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration.
Topics: Adult; Animals; Animals, Genetically Modified; Disease Models, Animal; Disease Progression; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Opsins; Rabbits; Retina; Retinal Degeneration; Retinitis Pigmentosa; Taurine | 2011 |
Stability of BRAF V600E mutation in metastatic melanoma: new insights for therapeutic success?
Topics: Amino Acid Substitution; Disease Progression; Glutamic Acid; Humans; Melanoma; Mutation, Missense; Neoplasm Metastasis; Prognosis; Proto-Oncogene Proteins B-raf; Selection, Genetic; Skin Neoplasms; Treatment Outcome; Valine | 2011 |
Is there evidence for neurotoxicity in the prodromal and early stages of schizophrenia?
Topics: Caudate Nucleus; Disease Progression; Glutamic Acid; Humans; Neurotoxins; Schizophrenia | 2011 |
BRAFV600E mutation, TIMP-1 upregulation, and NF-κB activation: closing the loop on the papillary thyroid cancer trilogy.
Topics: Adult; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Neoplasm Invasiveness; NF-kappa B; Proto-Oncogene Proteins B-raf; Signal Transduction; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Up-Regulation; Valine | 2011 |
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cell Communication; Cell Death; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Disease Progression; Glutamic Acid; Humans; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Motor Neurons; Nerve Growth Factor; Receptor, Nerve Growth Factor; Signal Transduction; Superoxide Dismutase | 2011 |
N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Temporal Lobe | 2011 |
Glutamatergic changes in the cerebral white matter associated with schizophrenic exacerbation.
Topics: Adult; Brain; Brain Chemistry; Case-Control Studies; Disease Progression; Excitatory Amino Acids; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroimaging; Parietal Lobe; Schizophrenia | 2012 |
Urine metabolomics analysis for biomarker discovery and detection of jaundice syndrome in patients with liver disease.
Topics: Adult; Alanine; Aspartic Acid; Biomarkers; Chromatography, High Pressure Liquid; Disease Progression; Female; Glutamic Acid; Humans; Jaundice; Ketone Bodies; Liver Diseases; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Multivariate Analysis; Prognosis; Reproducibility of Results; Sensitivity and Specificity | 2012 |
A 9-year follow-up of a girl with pyridoxine (vitamin B6)-dependent seizures: magnetic resonance spectroscopy findings.
Topics: Adolescent; Anticonvulsants; Aspartic Acid; Biomarkers; Brain; Child; Creatinine; Disease Progression; Epilepsy; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Predictive Value of Tests; Pyridoxine; Treatment Outcome; Vitamin B Complex | 2012 |
Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Cell Count; Disease Models, Animal; Disease Progression; Endpoint Determination; Female; Gene Knock-In Techniques; Glutamic Acid; Huntington Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Neostriatum; Nerve Tissue Proteins; Neurons; Neurophysiology; Organ Size; Repetitive Sequences, Nucleic Acid; Swimming; Synaptic Transmission | 2012 |
Outcome in prostate cancer: association with endothelial nitric oxide synthase Glu-Asp298 polymorphism at exon 7.
Topics: Aged; Aspartic Acid; Bone Neoplasms; Disease Progression; Exons; Genotype; Glutamic Acid; Humans; Logistic Models; Male; Middle Aged; Neoplasm Metastasis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Prognosis; Prostatic Neoplasms; Treatment Outcome | 2002 |
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Disease Progression; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Huntington Disease; In Vitro Techniques; Mice; Neural Pathways; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Potassium Channel Blockers; Riluzole; Tetrodotoxin | 2003 |
Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Disease Models, Animal; Disease Progression; Drug Resistance; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Immunoblotting; Neuroprotective Agents; Organ Specificity; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Riluzole; Spinal Cord; Superoxide Dismutase; Symporters; Synaptosomes; Transgenes | 2003 |
Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus.
Topics: Acetates; Animals; Astrocytes; Biomarkers; Brain Stem; Carbon Isotopes; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Hydrocephalus; Kaolin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Taurine; Telencephalon | 2003 |
Acute and subchronic MPTP administration differentially affects striatal glutamate synaptic function.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acute Disease; Animals; Chronic Disease; Corpus Striatum; Disease Models, Animal; Disease Progression; Drug Administration Schedule; Glutamic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microdialysis; Microscopy, Immunoelectron; Parkinson Disease, Secondary; Presynaptic Terminals; Protein Subunits; Receptors, Glutamate; Synapses; Tyrosine 3-Monooxygenase | 2003 |
Opioid peptide release in the rat hippocampus after kainic acid-induced status epilepticus.
Topics: Animals; Disease Models, Animal; Disease Progression; Down-Regulation; Dynorphins; Enkephalins; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Opioid Peptides; Rats; Rats, Wistar; Reaction Time; Status Epilepticus | 2003 |
Functional changes of glial glutamate transporter GLT-1 during ischemia: an in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Extracellular Space; Glutamic Acid; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microdialysis; Time Factors | 2003 |
Kynurenic acid synthesis in cerebral cortical slices of rats with progressing symptoms of thioacetamide-induced hepatic encephalopathy.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Disease Progression; Glutamic Acid; Hepatic Encephalopathy; Kynurenic Acid; Organ Culture Techniques; Rats; Rats, Wistar; Thioacetamide; Transaminases | 2004 |
Limbic epileptogenicity, cell loss and axonal reorganization induced by audiogenic and amygdala kindling in wistar audiogenic rats (WAR strain).
Topics: Acoustic Stimulation; Amygdala; Animals; Cell Count; Disease Models, Animal; Disease Progression; Epilepsy, Reflex; Epilepsy, Tonic-Clonic; Female; Genetic Predisposition to Disease; Glutamic Acid; Hippocampus; Kindling, Neurologic; Limbic System; Mossy Fibers, Hippocampal; Nerve Degeneration; Neuronal Plasticity; Presynaptic Terminals; Rats; Rats, Mutant Strains; Rats, Wistar | 2004 |
Astroglial plasticity and glutamate function in a chronic mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Biological Transport; Cell Count; Cell Size; Chronic Disease; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neostriatum; Parkinsonian Disorders; Probenecid; Sodium; Synapses | 2004 |
Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Disease Models, Animal; Disease Progression; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Magnetic Resonance Imaging; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Presenilin-2; Spectrum Analysis | 2005 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Coma; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Occipital Lobe; Parietal Lobe; Predictive Value of Tests; Recovery of Function; Up-Regulation | 2004 |
The presence of glutamic acid at positions 71 or 74 in pocket 4 of the HLA-DRbeta1 chain is associated with the clinical course of multiple sclerosis.
Topics: Alleles; Binding Sites; Disease Progression; Genotype; Glutamic Acid; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Multiple Sclerosis, Chronic Progressive | 2005 |
Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Binding, Competitive; Disease Progression; Down-Regulation; Enzyme Activation; Female; Frontal Lobe; Glutamic Acid; Guanosine Triphosphate; Humans; Isoenzymes; Lewy Body Disease; Male; Middle Aged; Neurons; Phospholipase C beta; Radioligand Assay; Receptors, Metabotropic Glutamate; Signal Transduction; Type C Phospholipases | 2005 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke.
Topics: Aged; Aged, 80 and over; Animals; Astrocytes; Biological Transport; Brain Chemistry; Cells, Cultured; Disease Progression; Excitatory Amino Acid Transporter 2; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Middle Aged; Point Mutation; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Rats; RNA-Binding Proteins; Stroke; Transcription Factor AP-2; Transfection | 2006 |
Deterioration in acute ischemic stroke as the target for neuroprotection.
Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Blood Pressure; Body Temperature; Brain; Brain Ischemia; Cerebrovascular Circulation; Clinical Trials as Topic; Collateral Circulation; Cytokines; Disease Progression; Encephalitis; Glutamic Acid; Humans; Neuroprotective Agents; Stroke | 2006 |
Excitatory aminoacid neurotransmitters in schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Bangladesh; Case-Control Studies; Disease Progression; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia | 2005 |
High extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure.
Topics: Adolescent; Adult; Astrocytes; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Craniocerebral Trauma; Disease Progression; Extracellular Fluid; Glutamic Acid; Humans; Hyperkalemia; Intracranial Hypertension; Lactic Acid; Microdialysis; Potassium; Predictive Value of Tests; Regression Analysis; Up-Regulation; Water-Electrolyte Imbalance | 2000 |
Tumor-derived fibronectin is involved in melanoma cell invasion and regulated by V600E B-Raf signaling pathway.
Topics: Cells, Cultured; Disease Progression; Early Growth Response Protein 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibronectins; Glutamic Acid; Humans; Melanocytes; Melanoma; Mutation; Neoplasm Invasiveness; Proto-Oncogene Proteins B-raf; Signal Transduction; Valine | 2007 |
VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat.
Topics: Animals; Behavior, Animal; Disease Progression; Female; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Immunohistochemistry; Microscopy, Confocal; Motor Neurons; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Sacrococcygeal Region; Spinal Cord Injuries; Tail; Vesicular Glutamate Transport Protein 1 | 2007 |
Progressive sutural cataract associated with a BFSP2 mutation in a Chinese family.
Topics: Adolescent; Adult; Asian People; Base Sequence; Cataract; Child; Disease Progression; Exons; Eye Proteins; Female; Gene Deletion; Genetic Linkage; Glutamic Acid; Haplotypes; Humans; Intermediate Filament Proteins; Male; Mutation; Pedigree | 2006 |
A Japanese family with early-onset ataxia with motor and sensory neuropathy.
Topics: Adult; Age of Onset; Cerebellum; Disease Progression; Female; Genes, Recessive; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glutamic Acid; Hereditary Sensory and Motor Neuropathy; Humans; Japan; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Pedigree; Peripheral Nerves; Spinocerebellar Degenerations; Up-Regulation | 2007 |
Abnormal intracortical facilitation in early-stage Huntington's disease.
Topics: Action Potentials; Adult; Disease Progression; Electromyography; Female; Glutamic Acid; Humans; Huntington Disease; Male; Middle Aged; Motor Cortex; Neural Conduction; Transcranial Magnetic Stimulation | 2007 |
BRAF V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Carcinoma; Disease Progression; DNA Mutational Analysis; Female; Gene Frequency; Glutamic Acid; Humans; Male; Middle Aged; Models, Biological; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Neoplasms; Valine | 2007 |
MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes.
Topics: Animals; Aspartic Acid; Astrocytes; Body Water; Brain; Choline; Creatine; Diffusion; Disease Models, Animal; Disease Progression; Gliosis; Glucose; Glutamic Acid; Hyperkinesis; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microglia; Prion Diseases | 2007 |
Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients.
Topics: Adult; Ammonia; Biomarkers; Brain; Brain Mapping; Cerebral Cortex; Choline; Citrulline; Citrullinemia; Coma; Diffusion Magnetic Resonance Imaging; Disease Progression; Early Diagnosis; Fatal Outcome; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Hyperammonemia; Inositol; Magnetic Resonance Spectroscopy; Male; Predictive Value of Tests | 2007 |
Paradoxical upregulation of glutamatergic presynaptic boutons during mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Cognition Disorders; Cohort Studies; Disease Progression; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Neurons; Neuropsychological Tests; Plaque, Amyloid; Prefrontal Cortex; Presynaptic Terminals; Severity of Illness Index; Up-Regulation | 2007 |
Plasma glutamate and glycine levels in patients with amyotrophic lateral sclerosis: the effect of riluzole treatment.
Topics: Aged; Amyotrophic Lateral Sclerosis; Chromatography, High Pressure Liquid; Disease Progression; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neuroprotective Agents; Riluzole; Sex Characteristics | 2008 |
Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Axons; B-Lymphocytes; CD11b Antigen; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Disease Progression; Fullerenes; Glutamic Acid; Memory; Mice; Molecular Structure; Multiple Sclerosis; Oxidative Stress; T-Lymphocytes | 2008 |
[Neurotransmission mechanism of movement disorders in multiple sclerosis].
Topics: Adolescent; Adult; Aspartic Acid; Disease Progression; Female; Glutamic Acid; Humans; Male; Middle Aged; Motor Activity; Movement Disorders; Multiple Sclerosis; Neuromuscular Junction; Severity of Illness Index; Synaptic Transmission | 2007 |
Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease.
Topics: Aged; Alzheimer Disease; Amino Acid Sequence; Apolipoprotein E4; Aspartic Acid; Brain; Disease Progression; Female; Genotype; Glutamic Acid; Humans; Immunohistochemistry; Male; Molecular Weight; Neurofibrillary Tangles; Peptide Hydrolases; Predictive Value of Tests; Protein Structure, Tertiary; Proteomics; Severity of Illness Index; tau Proteins | 2008 |
Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.
Topics: Animals; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chromones; Disease Progression; Glutamic Acid; Humans; MAP Kinase Signaling System; Melanocytes; Melanoma; Mice; Morpholines; Mutant Proteins; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Signal Transduction; Valine | 2008 |
Duration of glutamate release after acute ischemic stroke.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Cerebrovascular Disorders; Disease Progression; Female; Glutamic Acid; Humans; Male; Middle Aged; Time Factors | 1997 |
Orthotopic liver transplantation for adult-onset type II citrullinaemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Ammonia; Arginine; Argininosuccinate Synthase; Brain Edema; Cause of Death; Citrulline; Diet, Protein-Restricted; Disease Progression; Fatal Outcome; Glutamic Acid; Hepatic Encephalopathy; Humans; Immunohistochemistry; Liver; Liver Transplantation; Male; Prognosis; Referral and Consultation | 1997 |
Glutamate and taurine are increased in ventricular cerebrospinal fluid of severely brain-injured patients.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Brain Concussion; Brain Edema; Brain Injuries; Cerebral Ventricles; Disease Progression; Female; Glasgow Coma Scale; Glutamic Acid; Humans; Longitudinal Studies; Male; Middle Aged; Monitoring, Physiologic; Severity of Illness Index; Taurine | 1999 |
Brain temperature modifies glutamate neurotoxicity in vivo.
Topics: Analysis of Variance; Animals; Body Temperature; Brain; Brain Injuries; Carbon Radioisotopes; Disease Models, Animal; Disease Progression; Glutamic Acid; Hyperthermia, Induced; Hypothermia, Induced; Male; Microdialysis; Nerve Degeneration; Neurons; Rats; Rats, Wistar; Sucrose; Time Factors | 1999 |
Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Blood Flow Velocity; Brain; Carrier Proteins; Cerebral Cortex; Cerebrovascular Circulation; Corpus Striatum; Disease Progression; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Neuroglia; Neurons; Oligonucleotides, Antisense; Rats; Rats, Inbred SHR; Survival Rate; Symporters | 2001 |
Glutamate, interleukin-6, and early clinical worsening in patients with acute stroke.
Topics: Acute Disease; Blood Glucose; Cohort Studies; Disease Progression; Glutamic Acid; Humans; Interleukin-6; Predictive Value of Tests; Severity of Illness Index; Stroke | 2001 |
Proinflammatory cytokines and glutamate in acute stroke.
Topics: Acute Disease; Cytokines; Disease Progression; Glutamic Acid; Inflammation; Interleukin-6; Predictive Value of Tests; Stroke | 2001 |
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anticonvulsants; Disease Progression; Electrophysiology; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Imidazoles; In Vitro Techniques; Longevity; Mice; Mice, Transgenic; Muscle, Skeletal; Neurons; Patch-Clamp Techniques; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Superoxide Dismutase | 2001 |
Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Behavior, Animal; Blotting, Western; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Transgenic; RNA, Messenger; Spinal Cord; Superoxide Dismutase | 2001 |
Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients.
Topics: Age Factors; Aged; Amyotrophic Lateral Sclerosis; Cerebrospinal Fluid; Chromatography, High Pressure Liquid; Cohort Studies; Colorimetry; Disease Progression; Female; Glutamic Acid; Humans; Male; Middle Aged; Muscle Weakness; Neurons; Paresis; Rhombencephalon; Sex Factors; Spinal Cord | 2002 |
Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target.
Topics: Aged; Biomarkers; Brain Infarction; Disease Progression; Encephalitis; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Logistic Models; Male; Middle Aged; Odds Ratio; Predictive Value of Tests; Prognosis; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2002 |
Multiple panel of biomarkers for TIA/stroke evaluation.
Topics: Adult; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Autoantibodies; Biomarkers; Diagnosis, Differential; Disease Progression; Female; Glutamic Acid; Glycine; Homocysteine; Humans; Hypertension; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Neuroprotective Agents; Predictive Value of Tests; Receptors, N-Methyl-D-Aspartate; Stroke; Tomography, X-Ray Computed | 2002 |
Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury.
Topics: Animals; Calcium-Binding Proteins; Cerebral Cortex; Disease Progression; Glutamic Acid; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Membrane Glycoproteins; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Phosphorylation; Phosphotyrosine; Rats; Rats, Wistar; Synapsins; Synaptic Transmission; Synaptophysin; Synaptotagmins; Time | 2002 |
Malignant infarction in cats after prolonged middle cerebral artery occlusion: glutamate elevation related to decrease of cerebral perfusion pressure.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Brain Edema; Cats; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Disease Progression; Glutamic Acid; Infarction, Middle Cerebral Artery; Intracranial Pressure; Laser-Doppler Flowmetry; Microdialysis; Predictive Value of Tests; Tomography, Emission-Computed | 2002 |
Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice.
Topics: Aging; Animals; Ataxia; Calcium Channel Blockers; Calcium Channels; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cerebellum; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Homozygote; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Patch-Clamp Techniques; Purkinje Cells; Receptors, Glutamate; Synaptic Transmission | 2002 |