Compounds > glutamic acid

glutamic acid and Depressive Disorder

glutamic acid has been researched along with Depressive Disorder in 103 studies

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.91)18.7374
1990's2 (1.94)18.2507
2000's34 (33.01)29.6817
2010's60 (58.25)24.3611
2020's4 (3.88)2.80

Authors

AuthorsStudies
Bokhan, NA; Davydova, TV; Galkin, SA; Nevidimova, TI; Savochkina, DN; Vetrile, LA; Zakharova, IA1
Lang, UE; Liwinski, T1
Cubała, WJ; Włodarczyk, A1
Dwivedi, Y; Wang, Q1
Andres-Mach, M; Chudzik, A; Kochalska, K; Kozioł, P; Oakden, W; Orzylowska, A; Pankowska, A; Pietura, R; Rola, R; Stanisz, GJ; Słowik, T; Łazorczyk, A1
Deng, JH; Gao, XJ; Han, Y; Li, SX; Liu, LJ; Lu, L; Meng, SQ; Shi, J; Sun, CY; Wen, Q; Xu, DF; Xu, LZ; Xue, YX; Yuan, K; Yuan, M; Zhang, RX; Zhao, M; Zhu, WL1
Cho, IH; Choi, M; Han, JK; Jeong Kim, S; Kim, BH; Kim, SJ; Kwon, SH; Kwon, YJ; Shin, JC; Ye, SK; Yi, EH1
Haiyan, Z; Hui, Z; Jiahui, C; Lei, W; Qiuxia, Z; Xiaoquan, Y; Xinlong, M; Yali, W; Yilong, Y1
Bermudez, I; Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Li, Y; Sanchez, C1
Bermudez, I; Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Li, Y; Pehrson, A; Sanchez, C1
Cavero, I; Charpeaud, T; Garay, R; Kim, YK; Skolnick, P; Zarate, CA1
Aboul-Fotouh, S; Asaad, T; Ghanem, MH; Habib, M; Kassim, SK1
Dick, TE; Jacono, FJ; Litvin, DG; Smith, CB1
Cao, YJ; Cheng, Y; Wang, Q; Zhang, Y; Zheng, XX1
Broderick, G; Craddock, TJA; Fletcher, MA; Klimas, NG; Morris, M; Nierenberg, B; Rice, MA; Tory Toole, J; Zysman, J1
Artigas, F; Castañé, A; Gasull-Camós, J; Martínez-Torres, S; Ozaita, A; Tarrés-Gatius, M1
Chen, GD; Chou, D; Ho, YC; Hsieh, MC; Lai, CY; Lee, AS; Lin, TB; Peng, HY; Wang, HH; Wen, YC; Yang, PS1
Chen, JL; Du, GH; Gao, Y; He, XY; Qin, XM; Tian, JS; Xiang, H1
Cubała, WJ; Gałuszko-Węgielnik, M; Górska, N; Słupski, J; Wiglusz, MS1
Baek, JH; Cho, GJ; Choi, WS; Chung, HJ; Go, BS; Jung, DH; Kang, SS; Kim, HJ; Lee, DH; Lee, DK; Roh, GS; Son, H; Sontakke, SB1
Chen, C; Chen, J; Kang, Y; Li, G; Li, H; Lin, W; Liu, Y; Wang, F; Wu, J; Xu, H; Xu, J; Xu, Z1
Konen, C; Niederst, E1
Duman, RS; Krystal, JH; Sanacora, G1
Kalinina, TS; Kiselev, AV; Stovbun, SV; Vostrikova, EV1
Pilc, A; Skolnick, P; Wierońska, JM1
Bagga, P; Chakravarty, S; Khandelwal, N; Kumar, A; Maitra, S; Noronha, JM; Patel, AB; Veeraiah, P1
Flight, MH1
Tanaka, K1
Abdullah, O; Bogdanov, VB; Bogdanova, OV; Kanekar, S; Prescot, AP; Renshaw, PF1
Dantzer, R; Walker, AK1
Du, M; Hu, ZB; Huang, F; Li, J; Muhtar, W; Shi, HL; Wang, TT; Wu, H; Wu, XJ; Yang, L; Zhang, BB1
Davies, H; Fang, M; Hu, Z; Li, W; Ling, S; Yang, Y1
Borchardt, V; Dou, W; Genz, A; He, H; Heinze, HJ; Krause, AL; Li, M; Li, W; Lord, A; Metzger, CD; Safron, A; van Tol, MJ; Walter, M1
Bumgardner, AL; Fadel, JR; Gabriel, C; Grillo, CA; Hang, A; Macht, VA; Mocaër, E; Piroli, GG; Reagan, LP; Risher, M1
Holst, B; Młyniec, K; Nowak, G; Singewald, N1
Franceschelli, A; Herchick, S; Pitychoutis, PM; Sens, J; Thelen, C1
Liu, C; Liu, G; Zhang, XN1
Arnone, D; Cavanagh, J; Condon, B; Jauhar, S; Mumuni, AN1
Adell, A; Berrocoso, E; Campa, L; Castañé, A; Galofré, M; Grifoll-Escoda, M; Jiménez-Sánchez, L; López-Gil, X; Pérez-Caballero, L1
Baker, G; Benson, C; Dursun, S; Jesudasan, SJ; Kerr, B; Mifflin, K1
Adell, A; Campa, L; Díaz, Á; Jiménez-Sánchez, L; Linge, R; Pazos, A; Pilar-Cuéllar, F; Vidal, R1
Bao, AM; Wu, JL; Wu, SH; Yu, SY1
Fu, Z; Gao, Y; Guo, F; Huang, C; Li, Y; Ma, Y; Shen, F; Zhang, B1
Chen, J; Cheng, K; Liao, L; Rao, C; Shi, H; Tang, J; Wang, Z; Wu, Y; Xie, P; Yang, Y; Zhao, M; Zhou, C; Zhou, J; Zhu, D1
Goel, RK; Singh, T1
Bonnet, U1
Ameis, SH; Croarkin, PE; Daskalakis, ZJ; Frye, MA; Husain, MM; Lewis, CP; Port, JD; Vande Voort, JL1
Abdelkader, NF; Abdelsalam, RM; Saad, MA1
Bhagwagar, Z; Hannestad, J; McNally, L1
Florkowski, A; Gałecka, E; Gałecki, P; Mrowicka, M; Pietras, T1
Sümegi, A1
Carroll, FI1
Cowen, PJ; Jezzard, P; Norbury, R; Selvaraj, S; Taylor, MJ1
Kanner, AM1
Kikuchi, T; Takeda, A; Tamano, H; Watanabe, M1
Alcaro, A; Hayes, DJ; Northoff, G; Panksepp, J; Witczak, J1
Müller, N1
Epel, ES; Mellon, SH; Reus, VI; Wolkowitz, OM1
Kunugi, H; Numakawa, T1
Inagaki, M; Iwai, T; Murasawa, H; Nakatani, A; Saitoh, A; Takahashi, K; Yamada, M; Yamaguchi, K; Yoshida, M1
Cowen, PJ; Mannie, ZN; Near, J; Norbury, R; Taylor, MJ1
Aso, E; Del Rio, J; Elizalde, N; Garcia-García, AL; Ramírez, MJ; Segura, V; Tordera, RM; Venzala, E1
Deuschle, M; Gass, P; Paslakis, G1
Farooqui, AA; Frisardi, V; Panza, F1
Crisafulli, C; Drago, A; Serretti, A; Sidoti, A1
Binder, EB; Czamara, D; Czisch, M; Heck, A; Hennings, J; Holsboer, F; Kloiber, S; Kohli, MA; Lucae, S; Menke, A; Müller-Myhsok, B; Sämann, P1
Bajbouj, M; Colla, M; Grimm, S; Heuser, I; Kronenberg, G; Luborzewski, A; Merkl, A; Schubert, F1
Dong, J; Liu, C; Liu, D; Liu, XB; Luo, J; Min, S; Wei, K1
Graeber, MB; Hickie, IB; Naismith, SL; Norrie, LM; Paradise, MB1
Cho, GJ; Choi, WS; Kang, SS; Kim, G; Kim, HJ; Kim, S; Lee, DH; Lee, Y; Roh, GS; Son, H1
Magistretti, P; Pralong, E; Stoop, R1
Arolt, V; Erfurth, A; Fiebich, M; Heindel, W; Hohmann, U; Michael, N; Ohrmann, P; Pfleiderer, B; Wolgast, M1
Dawson, LA; Li, P1
Becker, H; Blin, O; Micallef, J; Tardieu, S1
Holden, C1
SIUCHNINSKA, H1
Banerjee, SP; Bhandari, R; Ivey, J; Mirza, Y; Moore, GJ; Rose, M; Rosenberg, DR; Russell, A; Tang, J1
Appel, M; Epperson, CN; Gueorguieva, R; Krystal, JH; Mason, GF; Rothman, DL; Sanacora, G; Wu, YT1
Bermack, JE; Debonnel, G1
Kendell, SF; Krystal, JH; Sanacora, G1
Ashby, CR; Kawahara, R; Maeda, K; Mitani, H; Shirayama, Y; Yamada, T1
Mineur, YS; Picciotto, MR; Sanacora, G1
Collier, EF; Duman, RS; Girgenti, MJ; Newton, SS1
Owen, JC; Whitton, PS1
Duman, RS; Newton, SS; Ploski, JE1
Glodzik-Sobanska, L; Kozub, J; McHugh, P; Rich, KE; Slowik, A; Sobiecka, B; Szczudlik, A; Urbanik, A1
Palucha, A1
Ashworth, F; Bhagwagar, Z; Cowen, PJ; Evans, J; Jezzard, P; Matthews, PM; Sule, A; Wylezinska, M1
Rothstein, JD; Sattler, R1
Johnson, BG; Marek, GJ; Schoepp, DD; Witkin, JM1
Markou, A; Paterson, NE1
Fadel, J; Grillo, CA; Pasumarthi, RK; Piroli, GG; Reagan, LP; Reznikov, LR1
Huang, Z; Mao, QQ1
Mineur, YS; Picciotto, MR; Vieyra-Reyes, P1
Howells, FM; Russell, VA1
Li, XJ; Li, YB; Li, YH; Wang, R; Wu, HL; Xu, Y1
Claus, D; Kim, JS; Kornhuber, HH; Schmid-Burgk, W1
Kornhuber, J; Weller, M1
Bains, S; Jeetle, J; Michael-Titus, AT; Whelpton, R1
Auer, DP; Czisch, M; Murck, H; Steiger, A; Struttmann, T; Wetter, T1
Bowen, DM; Francis, PT; Lowe, SL; Pangalos, MN; Procter, AW; Steele, JE1
Bartlett, JR; Bowen, DM; Bridges, PK; Bruton, CJ; Francis, PT; Lowe, SL; Najlerahim, A; Poynton, A; Procter, AW1

Reviews

33 review(s) available for glutamic acid and Depressive Disorder

ArticleYear
Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review.
    Nutrients, 2023, Sep-04, Volume: 15, Issue:17

    Topics: Depressive Disorder; Folic Acid; Glutamic Acid; Humans; Suicidal Ideation; Suicide

2023
Advances in novel molecular targets for antidepressants.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 01-10, Volume: 104

    Topics: Antidepressive Agents; Brain; Depressive Disorder; Drug Discovery; gamma-Aminobutyric Acid; Glutamic Acid; Humans

2021
Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments.
    Neuron, 2019, 04-03, Volume: 102, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Cerebral Cortex; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Interneurons; Ketamine; Neurons; Sex Factors; Synaptic Transmission

2019
Glutamate-based antidepressants: preclinical psychopharmacology.
    Biological psychiatry, 2013, Jun-15, Volume: 73, Issue:12

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Psychopharmacology

2013
[Role of glutamate transporters in the pathophysiology of major mental illnesses].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2013, Volume: 142, Issue:6

    Topics: Amino Acid Transport System X-AG; Animals; Autistic Disorder; Depressive Disorder; Disease Models, Animal; Drug Discovery; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Mice; Molecular Targeted Therapy; Mutation; Obsessive-Compulsive Disorder; Schizophrenia

2013
Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?
    Journal of neural transmission (Vienna, Austria : 1996), 2014, Volume: 121, Issue:8

    Topics: Animals; Blood-Brain Barrier; Depressive Disorder; Glutamic Acid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Neuroimmunomodulation; Quinolinic Acid

2014
Systematic hypothesis for post-stroke depression caused inflammation and neurotransmission and resultant on possible treatments.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Depressive Disorder; Encephalitis; Glutamic Acid; Humans; Inflammation Mediators; Nerve Growth Factors; Neural Stem Cells; Stroke; Synaptic Transmission

2014
GPR39 Zn(2+)-sensing receptor: a new target in antidepressant development?
    Journal of affective disorders, 2015, Mar-15, Volume: 174

    Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Glutamic Acid; Humans; Learning; Memory; Molecular Targeted Therapy; Mood Disorders; Neuroprotective Agents; Receptors, G-Protein-Coupled; Signal Transduction; Up-Regulation; Weight Gain; Weight Loss; Zinc

2015
Indirect evidence of selective glial involvement in glutamate-based mechanisms of mood regulation in depression: meta-analysis of absolute prefrontal neuro-metabolic concentrations.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:8

    Topics: Affect; Depressive Disorder; Glutamic Acid; Humans; Prefrontal Cortex

2015
Biogenic Amines and the Amino Acids GABA and Glutamate: Relationships with Pain and Depression.
    Modern trends in pharmacopsychiatry, 2015, Volume: 30

    Topics: Biogenic Amines; Chronic Pain; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Humans

2015
How much alcohol is in ketamine's antidepressant action?
    Life sciences, 2017, Jan-01, Volume: 168

    Topics: Anesthetics, Dissociative; Animals; Antidepressive Agents; Brain; Depressive Disorder; Dopamine; Ethanol; Glutamic Acid; Humans; Ketamine

2017
Inflammation, glutamate, and glia in depression: a literature review.
    CNS spectrums, 2008, Volume: 13, Issue:6

    Topics: Animals; Astrocytes; Brain; Depressive Disorder; Disease Models, Animal; Glutamic Acid; Humans; Inflammation Mediators; Kynurenine; Microglia; Neuroglia; Neuronal Plasticity; Rats; Receptors, Glutamate; Serotonin

2008
[Calcium ions, glutaminate acid, hypothalamic-pituitary-adrenal axis, calcium dependent ATP-ase as causes of oxidative damage in depression patients (part II)].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 24, Issue:139

    Topics: Apoptosis; Calcium; Calcium-Transporting ATPases; Depressive Disorder; Glutamic Acid; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Mitochondria; Necrosis; Neurons; Oxidative Phosphorylation; Reactive Oxygen Species; Tricarboxylic Acids

2008
[Mood stabilizers--past, present and future].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:1

    Topics: Affect; Antimanic Agents; Bipolar Disorder; Calcium; Carbamazepine; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Lithium Compounds; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mood Disorders; Triazines; Valproic Acid

2008
Antagonists at metabotropic glutamate receptor subtype 5: structure activity relationships and therapeutic potential for addiction.
    Annals of the New York Academy of Sciences, 2008, Volume: 1141

    Topics: Alcoholism; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; CHO Cells; Cricetinae; Cricetulus; Depressive Disorder; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mice; Mice, Knockout; Protein Conformation; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Smoking; Structure-Activity Relationship; Substance-Related Disorders

2008
Depression and epilepsy: do glucocorticoids and glutamate explain their relationship?
    Current neurology and neuroscience reports, 2009, Volume: 9, Issue:4

    Topics: Animals; Comorbidity; Depressive Disorder; Epilepsy; Glucocorticoids; Glutamic Acid; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Quality of Life; Risk Factors; Suicide

2009
Is subcortical-cortical midline activity in depression mediated by glutamate and GABA? A cross-species translational approach.
    Neuroscience and biobehavioral reviews, 2010, Volume: 34, Issue:4

    Topics: Animals; Brain; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Species Specificity

2010
COX-2 inhibitors as antidepressants and antipsychotics: clinical evidence.
    Current opinion in investigational drugs (London, England : 2000), 2010, Volume: 11, Issue:1

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Cyclooxygenase 2 Inhibitors; Cytokines; Depressive Disorder; Glutamic Acid; Humans; Inflammation; Kynurenine; Prostaglandins; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate

2010
Depression gets old fast: do stress and depression accelerate cell aging?
    Depression and anxiety, 2010, Volume: 27, Issue:4

    Topics: Arousal; Cellular Senescence; Chronic Disease; Comorbidity; Depressive Disorder; Glutamic Acid; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Inflammation Mediators; Mind-Body Relations, Metaphysical; Pituitary-Adrenal System; Stress, Psychological; Telomerase; Telomere

2010
[Possible interaction between glucocorticoid and BDNF function].
    Seikagaku. The Journal of Japanese Biochemical Society, 2010, Volume: 82, Issue:5

    Topics: Brain-Derived Neurotrophic Factor; Cerebral Cortex; Depressive Disorder; Glucocorticoids; Glutamic Acid; Humans; Neurotransmitter Agents; Receptor, trkB; Receptors, Glucocorticoid; Signal Transduction; Synaptic Transmission

2010
[The role of the glutamatergic system in pathophysiology and pharmacotherapy for depression: preclinical and clinical data].
    Fortschritte der Neurologie-Psychiatrie, 2011, Volume: 79, Issue:4

    Topics: Animals; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ketamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Riluzole; Stress, Psychological

2011
Late-life depression and Alzheimer's disease: the glutamatergic system inside of this mirror relationship.
    Brain research reviews, 2011, Jun-24, Volume: 67, Issue:1-2

    Topics: Aged; Aging; Alzheimer Disease; Animals; Comorbidity; Depressive Disorder; Glutamic Acid; Humans

2011
The molecular interaction between the glutamatergic, noradrenergic, dopaminergic and serotoninergic systems informs a detailed genetic perspective on depressive phenotypes.
    Progress in neurobiology, 2011, Sep-01, Volume: 94, Issue:4

    Topics: Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Depressive Disorder; Dopamine; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Mitogen-Activated Protein Kinases; Neural Pathways; Nitric Oxide; Norepinephrine; Phenotype; Protein Kinase C; Receptors, Dopamine; Serotonin; Signal Transduction

2011
The role of glia in late-life depression.
    International psychogeriatrics, 2012, Volume: 24, Issue:12

    Topics: Age of Onset; Aged; Autopsy; Brain; Cytokines; Depressive Disorder; Electrical Synapses; Gliosis; Glutamic Acid; Humans; Inflammation; Nerve Net; Neuroglia; Neuroimaging

2012
Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders.
    Progress in neurobiology, 2002, Volume: 67, Issue:3

    Topics: Bipolar Disorder; Brain; Depressive Disorder; Dopamine; Glutamic Acid; Humans; Limbic System; Neurotransmitter Agents; Norepinephrine; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia; Serotonin

2002
[Treatment of non-dopamine-dependent signs in parkinsonian syndromes: evaluation and results].
    Revue neurologique, 2003, Volume: 159, Issue:5 Pt 2

    Topics: Anti-Dyskinesia Agents; Botulinum Toxins; Cholinesterase Inhibitors; Clozapine; Dementia; Depressive Disorder; Dopamine; Glutamic Acid; Humans; Movement Disorders; Parkinsonian Disorders; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Treatment Outcome

2003
The role of sigma receptors in depression.
    Journal of pharmacological sciences, 2005, Volume: 97, Issue:3

    Topics: Animals; Antidepressive Agents; Calcium; Depressive Disorder; Glutamic Acid; Humans; Raphe Nuclei; Receptors, sigma; Serotonin

2005
GABA and glutamate systems as therapeutic targets in depression and mood disorders.
    Expert opinion on therapeutic targets, 2005, Volume: 9, Issue:1

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Drug Delivery Systems; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mood Disorders

2005
Are compounds acting at metabotropic glutamate receptors the answer to treating depression?
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:12

    Topics: Allosteric Regulation; Animals; Antidepressive Agents; Depression; Depressive Disorder; Drug Design; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ligands; Mice; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate

2006
Metabotropic glutamate receptors in the control of mood disorders.
    CNS & neurological disorders drug targets, 2007, Volume: 6, Issue:2

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Depressive Disorder; Glutamic Acid; Humans; Mood Disorders; Receptors, Metabotropic Glutamate; Synaptic Transmission

2007
Animal models and treatments for addiction and depression co-morbidity.
    Neurotoxicity research, 2007, Volume: 11, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Depressive Disorder; Dopamine Agents; Glutamic Acid; Humans; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Substance-Related Disorders

2007
[Research progress on therapeutic mechanism of depression treated by traditional chinese medicine].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:10

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Depressive Disorder; Drugs, Chinese Herbal; Glutamic Acid; Humans; Nerve Growth Factors; Phytotherapy

2007
Clinical correlations of the neurobiological changes of aging.
    Annales de medecine interne, 1990, Volume: 141 Suppl 1

    Topics: Aged; Aging; Alzheimer Disease; Amino Acids; Cerebral Cortex; Depressive Disorder; Energy Metabolism; Glutamates; Glutamic Acid; Humans; Neurons

1990

Trials

1 trial(s) available for glutamic acid and Depressive Disorder

ArticleYear
[A randomized, double-blind, placebo-controlled study of the efficacy and safety of ampasse in the treatment of chronic cerebral ischemia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2019, Volume: 119, Issue:4

    Topics: Aged; Brain Ischemia; Chronic Disease; Depressive Disorder; Double-Blind Method; Glutamic Acid; Humans; Hypertension; Middle Aged; Treatment Outcome

2019

Other Studies

69 other study(ies) available for glutamic acid and Depressive Disorder

ArticleYear
Correlation of Antibodies to Neurotransmitters in the Sera of Women with Alcohol Dependence and Depressive Disorders.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:6

    Topics: Alcoholism; Autoantibodies; Case-Control Studies; Depressive Disorder; Dopamine; Dysthymic Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Middle Aged; Norepinephrine; Serotonin

2021
Mechanisms of action of the ketogenic diet in depression.
    Neuroscience and biobehavioral reviews, 2019, Volume: 107

    Topics: Depression; Depressive Disorder; Diet, Ketogenic; Glutamic Acid; Humans; Mood Disorders

2019
Dietary supplementation with Lactobacillus rhamnosus JB-1 restores brain neurochemical balance and mitigates the progression of mood disorder in a rat model of chronic unpredictable mild stress.
    Nutrition research (New York, N.Y.), 2020, Volume: 82

    Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Choline; Depressive Disorder; Dietary Supplements; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Lacticaseibacillus rhamnosus; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Stress, Psychological

2020
Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects.
    Molecular psychiatry, 2018, Volume: 23, Issue:3

    Topics: Animals; Antidepressive Agents; Chronic Disease; Death-Associated Protein Kinases; Depression; Depressive Disorder; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stress, Psychological

2018
Dysfunction of Microglial STAT3 Alleviates Depressive Behavior via Neuron-Microglia Interactions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:10

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Coculture Techniques; Depressive Disorder; Disease Models, Animal; Glutamic Acid; Macrophage Colony-Stimulating Factor; Male; Mice, Transgenic; Microglia; Neurons; STAT3 Transcription Factor; Synaptic Transmission; Synaptosomes; Tissue Culture Techniques

2017
JIEYUANSHEN DECOCTION EXERTS ANTIDEPRESSANT EFFECTS ON DEPRESSIVE RAT MODEL VIA REGULATING HPA AXIS AND THE LEVEL OF AMINO ACIDS NEUROTRANSMITTER.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017, Volume: 14, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Disease Models, Animal; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypothalamo-Hypophyseal System; Magnoliopsida; Male; Neurotransmitter Agents; Phytotherapy; Pituitary-Adrenal System; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Stress, Psychological

2017
Contrasting effects of vortioxetine and paroxetine on pineal gland biochemistry in a tryptophan-depletion model of depression in female rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 10-03, Volume: 79, Issue:Pt B

    Topics: Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Depressive Disorder; Disease Models, Animal; Female; Glutamic Acid; Melatonin; Norepinephrine; Paroxetine; Pineal Gland; Piperazines; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA-Binding Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Tryptophan; Vortioxetine

2017
Effects of vortioxetine on biomarkers associated with glutamatergic activity in an SSRI insensitive model of depression in female rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 03-02, Volume: 82

    Topics: Administration, Oral; Animals; Biomarkers; Depressive Disorder; Disease Models, Animal; Female; Glutamic Acid; Paroxetine; Random Allocation; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vortioxetine

2018
The development of glutamate-based antidepressants is taking longer than expected.
    Drug discovery today, 2018, Volume: 23, Issue:10

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Drug Development; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Time Factors

2018
Behavioral effects of toll-like receptor-4 antagonist 'eritoran' in an experimental model of depression: role of prefrontal and hippocampal neurogenesis and γ-aminobutyric acid/glutamate balance.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disaccharides; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypothalamo-Hypophyseal System; Male; Neurogenesis; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological; Sugar Phosphates; Toll-Like Receptor 4

2018
Lung-injury depresses glutamatergic synaptic transmission in the nucleus tractus solitarii via discrete age-dependent mechanisms in neonatal rats.
    Brain, behavior, and immunity, 2018, Volume: 70

    Topics: Age Factors; Animals; Animals, Newborn; Bleomycin; Depression; Depressive Disorder; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Lung Injury; Male; Medulla Oblongata; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Synapses; Synaptic Transmission

2018
Involvement of SNARE complex in the hippocampus and prefrontal cortex of offspring with depression induced by prenatal stress.
    Journal of affective disorders, 2018, 08-01, Volume: 235

    Topics: Animals; Depressive Disorder; Female; Glutamic Acid; Hippocampus; Male; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; SNARE Proteins; Stress, Psychological; Synaptic Transmission; Synaptosomal-Associated Protein 25; Syntaxin 1; Temporal Lobe; Vesicle-Associated Membrane Protein 2

2018
Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1781

    Topics: Brain; Depressive Disorder; Glutamic Acid; Homeostasis; Humans; Models, Neurological; Neural Pathways; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission

2018
Serotonergic mechanisms involved in antidepressant-like responses evoked by GLT-1 blockade in rat infralimbic cortex.
    Neuropharmacology, 2018, 09-01, Volume: 139

    Topics: Animals; Antidepressive Agents; Cerebral Cortex; Citalopram; Depressive Disorder; Dorsal Raphe Nucleus; GABAergic Neurons; Glucose Transporter Type 1; Glutamic Acid; Kainic Acid; Male; Motor Activity; Piperazines; Proto-Oncogene Proteins c-fos; Pyridines; Random Allocation; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonergic Neurons; Serotonin; Serotonin Agents; Synaptic Transmission

2018
(2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
    Neuropharmacology, 2018, 09-01, Volume: 139

    Topics: Animals; Antidepressive Agents; Cell Membrane; Cytosol; Depressive Disorder; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Helplessness, Learned; Ketamine; Male; Miniature Postsynaptic Potentials; Neurons; Periaqueductal Gray; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Synapses; Tissue Culture Techniques

2018
[Comparative study of the corticosterone and glutamate induced PC12 cells depression model by 1H NMR metabolomics].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2017, Volume: 52, Issue:2

    Topics: Animals; Antioxidants; Corticosterone; Depression; Depressive Disorder; Fatty Acids; Glutamic Acid; Glycolysis; Metabolomics; PC12 Cells; Proton Magnetic Resonance Spectroscopy; Rats

2017
Role of copper in depression. Relationship with ketamine treatment.
    Medical hypotheses, 2018, Volume: 119

    Topics: Anesthetics; Animals; Antidepressive Agents; Copper; Depressive Disorder; Glutamic Acid; Hippocampus; Humans; Ions; Ketamine; Mice; Nerve Tissue Proteins; Neurons; Prion Proteins; Rats; Receptors, N-Methyl-D-Aspartate

2018
Glutamine has antidepressive effects through increments of glutamate and glutamine levels and glutamatergic activity in the medial prefrontal cortex.
    Neuropharmacology, 2018, Volume: 143

    Topics: Animals; Astrocytes; Depressive Disorder; Dietary Supplements; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Membrane Potentials; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Optogenetics; Prefrontal Cortex; Restraint, Physical; Stress, Psychological; Synaptic Transmission; Tissue Culture Techniques

2018
CSF glutamate level decreases in heavy smokers and negatively correlates with BDI scores.
    Psychiatry research, 2018, Volume: 270

    Topics: Adolescent; Adult; China; Correlation of Data; Depressive Disorder; Glutamic Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychometrics; Reference Values; Smoking; Young Adult

2018
Special Issue on Disease: New Advances in Psychiatry.
    Neuron, 2019, 04-03, Volume: 102, Issue:1

    Topics: Animals; Brain; Cerebellum; Depression, Postpartum; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Mental Disorders; Neural Pathways; Neuropsychiatry; Obsessive-Compulsive Disorder; Pregnancy; Pregnancy Complications; Primates; Psychiatry; Stress Disorders, Post-Traumatic; Substance-Related Disorders

2019
Dysfunctional glutamatergic and γ-aminobutyric acidergic activities in prefrontal cortex of mice in social defeat model of depression.
    Biological psychiatry, 2014, Aug-01, Volume: 76, Issue:3

    Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Depression; Depressive Disorder; Disease Models, Animal; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurons; Prefrontal Cortex; Social Behavior; Stress, Psychological

2014
Trial watch: phase II boost for glutamate-targeted antidepressants.
    Nature reviews. Drug discovery, 2013, Volume: 12, Issue:12

    Topics: Antidepressive Agents; Clinical Trials, Phase II as Topic; Depressive Disorder; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ketamine

2013
Neurochemical alterations in frontal cortex of the rat after one week of hypobaric hypoxia.
    Behavioural brain research, 2014, Apr-15, Volume: 263

    Topics: Alanine; Altitude; Animals; Corpus Striatum; Creatine; Depressive Disorder; Female; Frontal Lobe; Glutamic Acid; Glycine; Hippocampus; Hypoxia; Inositol; Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Swimming; Time Factors

2014
Simultaneous quantification of seven hippocampal neurotransmitters in depression mice by LC-MS/MS.
    Journal of neuroscience methods, 2014, May-30, Volume: 229

    Topics: Animals; Chromatography, Liquid; Depressive Disorder; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Methylprednisolone; Mice, Inbred C57BL; Neurotransmitter Agents; Norepinephrine; Regression Analysis; Sensitivity and Specificity; Serotonin; Tandem Mass Spectrometry

2014
Dissociation of glutamate and cortical thickness is restricted to regions subserving trait but not state markers in major depressive disorder.
    Journal of affective disorders, 2014, Volume: 169

    Topics: Adult; Biomarkers; Case-Control Studies; Depressive Disorder; Depressive Disorder, Major; Dissociative Disorders; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Neurotransmitter Agents; Organ Size; Young Adult

2014
Repeated restraint stress-induced atrophy of glutamatergic pyramidal neurons and decreases in glutamatergic efflux in the rat amygdala are prevented by the antidepressant agomelatine.
    Neuroscience, 2015, Jan-22, Volume: 284

    Topics: Acetamides; Animals; Antidepressive Agents; Atrophy; Basolateral Nuclear Complex; Corticosterone; Dendrites; Depressive Disorder; Disease Models, Animal; Glutamic Acid; Male; Neuronal Plasticity; Pyramidal Cells; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological

2015
Sex differences in the rapid and the sustained antidepressant-like effects of ketamine in stress-naïve and "depressed" mice exposed to chronic mild stress.
    Neuroscience, 2015, Apr-02, Volume: 290

    Topics: Animals; Antidepressive Agents; Aspartic Acid; Chronic Disease; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Glutamic Acid; Hippocampus; Ketamine; Male; Mice, Inbred C57BL; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Serotonin; Sex Characteristics; Stress, Psychological; Swimming; Time Factors

2015
Comparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats.
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Animals; Depressive Disorder; Dizocilpine Maleate; Electroconvulsive Therapy; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Learning Disabilities; Male; Maze Learning; Memory Disorders; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2015
Activation of AMPA Receptors Mediates the Antidepressant Action of Deep Brain Stimulation of the Infralimbic Prefrontal Cortex.
    Cerebral cortex (New York, N.Y. : 1991), 2016, Volume: 26, Issue:6

    Topics: Animals; Deep Brain Stimulation; Depressive Disorder; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats, Wistar; Receptors, AMPA; Serotonin

2016
Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors.
    Neuropharmacology, 2016, Volume: 103

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Cannabidiol; Depressive Disorder; Disease Models, Animal; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Olfactory Bulb; Prefrontal Cortex; Receptor, Serotonin, 5-HT1A; Serotonin; Synaptic Transmission

2016
A sensitive and practical RP-HPLC-FLD for determination of the low neuroactive amino acid levels in body fluids and its application in depression.
    Neuroscience letters, 2016, Mar-11, Volume: 616

    Topics: Aged; Aged, 80 and over; Amino Acids; Bipolar Disorder; Body Fluids; Case-Control Studies; Chromatography, High Pressure Liquid; Depression; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Mood Disorders

2016
The rapid antidepressant and anxiolytic-like effects of YY-21 involve enhancement of excitatory synaptic transmission via activation of mTOR signaling in the mPFC.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depressive Disorder; Disease Models, Animal; Glutamic Acid; Male; Mice, Inbred C57BL; Prefrontal Cortex; Random Allocation; Rats, Sprague-Dawley; Saponins; Stress, Psychological; Synaptic Transmission; Time Factors; Tissue Culture Techniques; TOR Serine-Threonine Kinases

2016
Hypothalamic Proteomic Analysis Reveals Dysregulation of Glutamate Balance and Energy Metabolism in a Mouse Model of Chronic Mild Stress-Induced Depression.
    Neurochemical research, 2016, Volume: 41, Issue:9

    Topics: Animals; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Mice, Inbred C57BL; Pituitary-Adrenal System; Proteomics; Stress, Physiological

2016
Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression.
    Epilepsy & behavior : E&B, 2016, Volume: 61

    Topics: Animals; Anticonvulsants; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Epilepsy; Glutamic Acid; Hindlimb Suspension; Kindling, Neurologic; Male; Mice; Neurochemistry; Norepinephrine; Pentylenetetrazole; Seizures; Serotonin; Treatment Outcome; Valproic Acid

2016
An Exploratory Study of Spectroscopic Glutamatergic Correlates of Cortical Excitability in Depressed Adolescents.
    Frontiers in neural circuits, 2016, Volume: 10

    Topics: Adolescent; Child; Depressive Disorder; Evoked Potentials, Motor; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Motor Cortex; Neural Inhibition; Transcranial Magnetic Stimulation

2016
Neuroprotective effect of nebivolol against cisplatin-associated depressive-like behavior in rats.
    Journal of neurochemistry, 2017, Volume: 141, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Antineoplastic Agents; Behavior, Animal; Brain Chemistry; Brain-Derived Neurotrophic Factor; Cell Survival; Cisplatin; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Male; Motor Activity; Nebivolol; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Wistar; Swimming

2017
Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients.
    Journal of affective disorders, 2009, Volume: 119, Issue:1-3

    Topics: Adolescent; Adult; Depressive Disorder; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult

2009
Susceptibility to stress in young rats after 2-week zinc deprivation.
    Neurochemistry international, 2010, Volume: 56, Issue:3

    Topics: Animals; Brain Chemistry; Corticosterone; Depressive Disorder; Dietary Supplements; Disease Models, Animal; Exocytosis; Fluorescent Dyes; Glutamic Acid; Hippocampus; Male; Mental Disorders; Neurons; Neuropsychological Tests; Potassium Chloride; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Stress, Psychological; Up-Regulation; Zinc

2010
Riluzole rapidly attenuates hyperemotional responses in olfactory bulbectomized rats, an animal model of depression.
    Behavioural brain research, 2011, Jan-01, Volume: 216, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Depressive Disorder; Disease Models, Animal; Emotions; Glutamic Acid; Male; Microdialysis; Olfactory Bulb; Prefrontal Cortex; Rats; Rats, Wistar; Riluzole; Statistics, Nonparametric

2011
Elevated cortical glutamate in young people at increased familial risk of depression.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:2

    Topics: Adolescent; Cerebral Cortex; Depression; Depressive Disorder; Depressive Disorder, Major; Family; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Risk Factors; Young Adult

2011
Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011, Volume: 21, Issue:1

    Topics: Animals; Behavior, Animal; Depression; Depressive Disorder; Disease Models, Animal; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Mood Disorders; Neurotransmitter Agents; Phenotype; Pleasure; RNA; Stress, Psychological; Sucrose; Time Factors; Vesicular Glutamate Transport Protein 1

2011
Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes.
    Psychoneuroendocrinology, 2012, Volume: 37, Issue:4

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Corticotropin-Releasing Hormone; Depression; Depressive Disorder; Dexamethasone; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phenotype; Pituitary-Adrenal Function Tests; Polymorphism, Single Nucleotide; Receptors, Metabotropic Glutamate

2012
Region-specific glutamate changes in patients with unipolar depression.
    Journal of psychiatric research, 2012, Volume: 46, Issue:8

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Brain Mapping; Depressive Disorder; Female; Follow-Up Studies; Glutamic Acid; Gyrus Cinguli; Humans; Imaging, Three-Dimensional; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Protons; Young Adult

2012
Effect of electroconvulsive shock on the glutamate level and the hyperphosphorylation of protein tau in depression rat models whose olfactory bulbs were removed.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2012, Volume: 34, Issue:3

    Topics: Animals; Depressive Disorder; Disease Models, Animal; Electroshock; Glutamic Acid; Hippocampus; Male; Olfactory Bulb; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins

2012
Glutamine deficiency in the prefrontal cortex increases depressive-like behaviours in male mice.
    Journal of psychiatry & neuroscience : JPN, 2013, Volume: 38, Issue:3

    Topics: 2-Aminoadipic Acid; Aminoisobutyric Acids; Analysis of Variance; Animals; Astrocytes; Depressive Disorder; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Male; Methionine; Mice; Mice, Inbred C57BL; Prefrontal Cortex

2013
Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients.
    Psychiatry research, 2003, Apr-01, Volume: 122, Issue:3

    Topics: Depressive Disorder; Electroconvulsive Therapy; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Treatment Outcome

2003
Effects of 5-HT(6) receptor blockade on the neurochemical outcome of antidepressant treatment in the frontal cortex of the rat.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Desipramine; Drug Synergism; Extracellular Space; Fluoxetine; Glutamic Acid; Male; Microdialysis; Neurons; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Thiophenes; Venlafaxine Hydrochloride

2003
Psychiatric drugs. Excited by glutamate.
    Science (New York, N.Y.), 2003, Jun-20, Volume: 300, Issue:5627

    Topics: Animals; Anxiety Disorders; Brain; Brain Diseases; Bridged Bicyclo Compounds; Clinical Trials as Topic; Depressive Disorder; Dopamine; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mental Disorders; Neurons; Pain; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Substance-Related Disorders; Synaptic Transmission

2003
[RESULTS OF THE TREATMENT OF DEPRESSIVE STATES WITH GERIOCAINE (H-3), GLUTAMIC ACID AND PREPARATION PLACENTA DURING THE INVOLUTIONAL STAGE].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1964, Mar-02, Volume: 19

    Topics: Depression; Depressive Disorder; Drug Therapy; Female; Glutamates; Glutamic Acid; Placenta; Pregnancy; Procaine; Tissue Extracts

1964
Reduced anterior cingulate cortex glutamatergic concentrations in childhood major depression.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:3

    Topics: Adolescent; Case-Control Studies; Cerebral Cortex; Depressive Disorder; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male

2004
Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.
    Archives of general psychiatry, 2004, Volume: 61, Issue:7

    Topics: Adult; Aspartic Acid; Choline; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Psychiatric Status Rating Scales; Severity of Illness Index

2004
[Also consider non-cognitive disorders].
    Krankenpflege Journal, 2005, Volume: 43, Issue:7-10

    Topics: Aged; Alzheimer Disease; Brain; Cognition Disorders; Depressive Disorder; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; Mental Disorders; Treatment Outcome

2005
Correlation between plasma levels of glutamate, alanine and serine with severity of depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6

    Topics: Adult; Alanine; Amino Acids; Chromatography, High Pressure Liquid; Depressive Disorder; Female; Glutamic Acid; Humans; Male; Psychiatric Status Rating Scales; Serine; Spectrometry, Fluorescence

2006
Antidepressant-like effects of ceftriaxone in male C57BL/6J mice.
    Biological psychiatry, 2007, Jan-15, Volume: 61, Issue:2

    Topics: Animals; Antidepressive Agents; Arousal; Ceftriaxone; Depressive Disorder; Disease Models, Animal; Exploratory Behavior; Fear; Feeding Behavior; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Motivation; Motor Activity; Reaction Time; Stress, Psychological

2007
Electroconvulsive seizure increases adult hippocampal angiogenesis in rats.
    The European journal of neuroscience, 2006, Volume: 24, Issue:3

    Topics: Animals; Biomarkers; Blood Vessels; Calcium-Binding Proteins; Carrier Proteins; Cell Adhesion Molecules; Dentate Gyrus; Depressive Disorder; Electroconvulsive Therapy; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Inhibitor of Differentiation Proteins; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Male; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Up-Regulation

2006
Effects of amantadine and budipine on antidepressant drug-evoked changes in extracellular dopamine in the frontal cortex of freely moving rats.
    Brain research, 2006, Oct-30, Volume: 1117, Issue:1

    Topics: Amantadine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Dopamine; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Fluid; Frontal Lobe; Glutamic Acid; Male; Microdialysis; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Up-Regulation

2006
Electroconvulsive seizure-induced gene expression profile of the hippocampus dentate gyrus granule cell layer.
    Journal of neurochemistry, 2006, Volume: 99, Issue:4

    Topics: Animals; Antigens, Differentiation; Brain-Derived Neurotrophic Factor; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Electroshock; Excitatory Amino Acid Transporter 3; Gene Expression; Gene Expression Profiling; Glutamic Acid; Male; Nerve Tissue Proteins; Neurons; Neuropeptide Y; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyrotropin-Releasing Hormone

2006
Single voxel proton magnetic resonance spectroscopy in post-stroke depression.
    Psychiatry research, 2006, Dec-01, Volume: 148, Issue:2-3

    Topics: Aged; Aspartic Acid; Cerebral Infarction; Choline; Creatine; Depressive Disorder; Dominance, Cerebral; Energy Metabolism; Female; Follow-Up Studies; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Synaptic Transmission; Tomography, X-Ray Computed

2006
Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects.
    Biological psychiatry, 2007, Mar-15, Volume: 61, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Occipital Lobe; Reference Values

2007
Targeting an old mechanism in a new disease-protection of glutamatergic dysfunction in depression.
    Biological psychiatry, 2007, Jan-15, Volume: 61, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Antidepressive Agents; Brain; Ceftriaxone; Depressive Disorder; Glutamic Acid; Humans; Mice; Neuroprotective Agents; Receptors, Glutamate; Treatment Outcome

2007
Acute stress-mediated increases in extracellular glutamate levels in the rat amygdala: differential effects of antidepressant treatment.
    The European journal of neuroscience, 2007, Volume: 25, Issue:10

    Topics: Acute Disease; Amygdala; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Axons; Depressive Disorder; Extracellular Fluid; Fluoxetine; Glutamic Acid; Male; Membrane Potentials; Microdialysis; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Stress, Psychological; Thiazepines; Up-Regulation

2007
Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors.
    Neuroscience letters, 2008, Mar-21, Volume: 434, Issue:1

    Topics: Administration, Oral; Animals; Anxiety Disorders; Behavior, Animal; Brain; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; Down-Regulation; Glutamic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neural Pathways; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Receptors, AMPA; Reward; Synaptic Transmission; Tobacco Use Disorder; Ventral Tegmental Area; Volition

2008
Glutamate-stimulated release of norepinephrine in hippocampal slices of animal models of attention-deficit/hyperactivity disorder (spontaneously hypertensive rat) and depression/anxiety-like behaviours (Wistar-Kyoto rat).
    Brain research, 2008, Mar-20, Volume: 1200

    Topics: Animals; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Depressive Disorder; Disease Models, Animal; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Norepinephrine; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Species Specificity; Synaptic Transmission

2008
Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB.
    Brain research, 2008, May-19, Volume: 1210

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Apoptosis; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Survival; Cells, Cultured; Cerebral Cortex; Curcumin; Depressive Disorder; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Glutamic Acid; Indole Alkaloids; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor, trkB; Up-Regulation

2008
Increased serum glutamate in depressed patients.
    Archiv fur Psychiatrie und Nervenkrankheiten, 1982, Volume: 232, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia

1982
Amantadine and the glutamate hypothesis of schizophrenia. Experiences in the treatment of neuroleptic malignant syndrome.
    Journal of neural transmission. General section, 1993, Volume: 92, Issue:1

    Topics: Adult; Amantadine; Antipsychotic Agents; Depressive Disorder; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Schizophrenia; Schizophrenic Psychology

1993
Imipramine and phenelzine decrease glutamate overflow in the prefrontal cortex--a possible mechanism of neuroprotection in major depression?
    Neuroscience, 2000, Volume: 100, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Aspartic Acid; Chromatography, High Pressure Liquid; Corpus Striatum; Depressive Disorder; Glutamic Acid; Imipramine; Male; Neuroprotective Agents; Phenelzine; Prefrontal Cortex; Rats; Rats, Wistar

2000
Increase in amino acids in the pons after sleep deprivation: a pilot study using proton magnetic resonance spectroscopy.
    Neuropsychobiology, 2002, Volume: 45, Issue:3

    Topics: Adult; Amino Acids; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Pons; Protons; Sleep Deprivation

2002
Brain amino acid concentrations and Ca2+-dependent release in intractable depression assessed antemortem.
    Brain research, 1989, Aug-14, Volume: 494, Issue:2

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Calcium; Depressive Disorder; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Humans; Male; Middle Aged

1989