glutamic acid has been researched along with Cognitive Decline in 82 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 41 (50.00) | 24.3611 |
| 2020's | 41 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farhoudi, M; Hosseini, L; Mahmoudi, J; Sadigh-Eteghad, S; Seyedaghamiri, F | 1 |
| Giordani, B; Hampstead, BM; Kairys, A; Lengu, K; Peltier, SJ; Ryan, S; Tyszkowski, T | 1 |
| Dai, H; Han, S; Li, Y; Rui, Q; Shen, Y; Wang, X; Wu, P; Wu, X; Xue, Q; Yang, Y | 1 |
| Chu, JM; Wong, GT; Zhang, Y | 1 |
| Bauminger, H; Gaisler-Salomon, I | 1 |
| Dacorro, L; Fingerhut, H; Gozdas, E; Gu, M; Hinkley, L; Hosseini, SMH; Hurd, R; Sacchet, MD | 1 |
| Cho, KM; Jo, JK; Kim, EJ; Kim, HW; Kim, JH; Kwon, SJ; Lee, G; Nguyen, CD; Park, SE; Seo, SH; Son, HS | 1 |
| Ambasta, RK; Chakraborty, P; Dewanjee, S; Dey, A; Gopalakrishnan, AV; Jha, NK; Jha, SK; Kumar, D; Ojha, S; Prakash, A; Swati, K | 1 |
| Dai, Z; Edden, RAE; Gao, F; Hui, SCN; Li, F; Li, M; Li, N; Li, X; Ma, W; Ren, F; Wu, L; Zong, W | 1 |
| Doppler, CEJ; Farrher, E; Fink, GR; Kalbe, E; Ophey, A; Pagel, N; Seger, A; Shah, NJ; Sommerauer, M | 1 |
| Chamberlain, SR; Jalal, B; Sahakian, BJ | 1 |
| Jiao, J; Lu, J; Wang, L; Wang, P; Yang, Y; Zhao, Y; Zheng, H | 1 |
| Chen, J; Gao, Y; Liu, N; Ma, L; Niu, J; Peng, X; Tang, S; Wu, J; Yu, J; Zheng, P | 1 |
| Grochecki, P; Kochalska, K; Kotlinska, JH; Marszalek-Grabska, M; Matosiuk, D; Michalak, A; Ner-Kluza, J; Pankowska, A; Suder, P | 1 |
| Czechowska, E; Pańczyszyn-Trzewik, P; Sowa-Kućma, M; Stachowicz, K | 1 |
| Kurian, GA; Ravindran, S | 1 |
| Lane, HY; Lin, CH; Yang, HT | 1 |
| Li, JN; Li, L; Liu, XL | 1 |
| Atiya, S; Bartha, R; Borrie, MJ; Brymer, C; Fogarty, J; Montero-Odasso, M; Pasternak, SH; Wong, D | 1 |
| Bi, N; Chen, XT; Fan, A; Niu, K; Tao, H; Wang, HL; Wang, T | 1 |
| Kraguljac, NV; Lahti, AC; Reddy-Thootkur, M | 1 |
| Chen, JM; Jiang, JJ; Liang, BY; Liao, YJ; Long, JY; Sapkota, K; Wei, JB; Zhou, Y; Zhou, YJ | 1 |
| Gurler, D; Kraguljac, NV; Lahti, AC; Martin, C; Tennant, B; Ver Hoef, L; White, DM | 1 |
| Kosari-Nasab, M; Salari, AA; Shokouhi, G | 1 |
| Jiang, T; Ke, Z; Ning, W; Shang, Y; Xiang, S; Yang, Z; Zhang, T; Zhang, Y | 1 |
| Bojesen, KB; Broberg, BV; Edden, RAE; Fagerlund, B; Glenthøj, BY; Glenthøj, LB; Hjorthøj, C; Krakauer, K; Kristensen, TD; Nordentoft, M; Rostrup, E; Wenneberg, C | 1 |
| Bartke, A; Britz, J; Broderick, SO; Delfino, K; Esperant-Hilaire, N; Findley, CA; Hascup, ER; Hascup, KN; Tischkau, S | 1 |
| Gulyaeva, NV | 1 |
| Ge, RL; Ji, W; Liu, J; Luo, J; Wan, Y; Zhang, Y | 1 |
| Chang, CH; Chen, SJ; Huang, CS; Lane, HY; Lin, CH; Lin, WC; Liu, CY; Yang, HT | 1 |
| Chen, L; Dai, Y; He, X; Huang, J; Jia, W; Jin, T; Li, J; Liang, S; Lin, H; Liu, W; Tao, J; Wu, J; Yang, M | 1 |
| Abuelezz, SA; Hendawy, N | 1 |
| Guo, Q; Guo, Y; Ji, E; Yang, S; Zhao, Y; Zheng, Y | 1 |
| Balcioglu, YH; Sen, M; Yesilkaya, UH | 1 |
| Burns, MP; Caccavano, AP; Cookson, MR; Harvey, AC; Kaganovich, A; Korthas, HT; Main, BS; Partridge, JG; Sloley, SS; Vicini, S; Winston, CN; Wu, JY; Zapple, DN | 1 |
| Chang, CY; Hsieh, YC; Kuo, MC; Lai, WS; Luo, DZ; Pei, JC | 1 |
| Bhardwaj, A; Bhardwaj, R; Dhawan, DK; Kaur, T; Sharma, S; Sharma, SK | 1 |
| Bansod, P; Swathi, KP; Tripathi, AS | 1 |
| Chen, H; Dai, Y; Fu, Y; Li, P; Li, X; Wang, F; Wen, W; Xu, S | 1 |
| Chen, X; Ding, Y; Gao, M; He, N; Lin, H; Shen, W; Xu, X; Zhu, B | 1 |
| Buchanan, RA; Consoli, DC; Dixit, S; Harrison, FE; May, JM; Nobis, WP; Tienda, AA; Wilcox, JM | 1 |
| Argyrousi, EK; Gulisano, W; Palmeri, A; Prickaerts, J; Puzzo, D; Van Goethem, NP | 1 |
| Deelchand, DK; Jack, CR; Kantarci, K; Kantarci, OH; Knopman, DS; Lesnick, TG; Lowe, VJ; Machulda, MM; Öz, G; Petersen, RC; Tosakulwong, N; Zeydan, B | 1 |
| Chaijaroonkhanarak, W; Pannangrong, W; Sripanidkulchai, B; Sripanidkulchai, K; Thorajak, P; Welbat, JU | 1 |
| Guo, Y; Jiang, H; Li, W; Liu, H; Nie, Z; Pu, X; Sun, Y; Wang, C; Xiong, X; Zhang, K; Zhang, X; Zhao, X | 1 |
| Snyder, GL; Vanover, KE | 1 |
| Matsumoto, K; Oka, JI; Sanai, E; Sasaki-Hamada, S; Suzuki, A | 1 |
| Denney, TS; Gawne, TJ; Lahti, AC; Reid, MA; Salibi, N; White, DM | 1 |
| Peleg-Raibstein, D; Wolfrum, C | 1 |
| Geerts, H; Roberts, P; Spiros, A | 1 |
| Arnsten, AFT; Datta, D | 1 |
| Ekladious, ST; El Sayed, NS | 1 |
| Mao, SS; Peng, Y; Qin, XF; Xu, D; Yao, ZW; Zhang, RJ; Zhou, XQ | 1 |
| Aslan, S; Chen, JR; Choi, C; Khan, DA; Kroll, JL; Patel, SV; Pinkham, AE; Ritz, T; Sherwood Brown, E; Steele, AM | 1 |
| Bagnato, F; Box, BA; Conrad, BN; Dula, AN; Landman, BA; Lyttle, BD; McKeithan, LJ; Newhouse, P; O'Grady, KP; Pawate, S; Smith, SA; Thompson, LM | 1 |
| Ahn, JH; Chen, BH; Hwang, IK; Kang, IJ; Kim, DW; Kim, YM; Lee, CH; Lee, JC; Lee, TK; Lee, YL; Park, JH; Won, MH; Yan, BC | 1 |
| Bowdler, P; Conway, ME; Coulthard, E; Harris, M; Hudd, F; Kauppinen, R; Knight, M; McCann, B; Shiel, A; Tsivos, D; Wearn, A; White, P | 1 |
| Ramanathan, M; Sankar, V; Venkatesh, G | 1 |
| Choo, BKM; Johan Arief, MFB; Kumari, Y; Kundap, UP; Othman, I; Shaikh, MF; Wong, CP; Yap, JL | 1 |
| Jiang, Q; Luo, B; Pang, Q | 1 |
| Arun, TM; Kesavadas, C; Menon, RN; Nandini, M; Thomas, B; Vijayakumari, AA | 1 |
| Chi, T; Ji, X; Li, Y; Liu, D; Liu, H; Liu, P; Qi, X; Xu, J; Zou, L | 1 |
| Guo, X; Han, D; He, J; Li, Y; Li, Z; Liu, H; Liu, T; Manyande, A; Tian, X; Wang, J; Xiang, H; Xu, F; Yang, N | 1 |
| Greig, NH; Li, Y; Pick, CG; Rachmany, L; Rubovitch, V; Tweedie, D; Wang, JY; Yu, QS | 1 |
| Chen, SD; Deng, YL; Huang, FJ; Jia, W; Liu, JJ; Ma, JF; Ren, RJ; Tang, HD; Wang, G; Wang, Y; Xu, W; Xu, XH; Zhang, YN; Zhao, AH; Zhou, Y | 1 |
| Buck, A; Edden, RA; Gietl, A; Henning, A; Hock, C; Kälin, AM; Kollias, S; Leh, SE; Luechinger, R; Michels, L; O'Gorman, R; Riese, F; Warnock, G; Zölch, N | 1 |
| Capo-Velez, CM; Lasalde-Dominicci, JA; Melendez, RI; Roman, C | 1 |
| El Sayed, NS; Sayed, AS | 1 |
| Choe, BY; Jahng, GH; Kim, HG; Lee, DW; Lee, KM; Oh, J; Paik, JW; Park, S; Rhee, HY; Ryu, CW; Shin, W | 1 |
| Abd El-Hamid, DH; Abdel-Rahman, MS; Abdel-Zaher, AO; Hamdy, MM | 1 |
| Chen, NH; Chu, SF; Jiang, YN; Li, CJ; Li, G; Luo, LM; Luo, P; Wang, ZZ; Xue, W; Zhang, DM; Zhou, H | 1 |
| Barak, S; Becker, KG; Becker, RE; Fukui, K; Greig, NH; Hoffer, BJ; Holloway, HW; Lehrmann, E; Li, Y; Luo, Y; Perez, E; Pick, CG; Rubovitch, V; Tamargo, IA; Tweedie, D; Van Praag, H; Wood, WH; Yu, QS; Zhang, Y | 1 |
| Fang, J; Liang, B | 1 |
| Shen, Y; Xu, Q; Yang, W; Zhu, C | 1 |
| Confort-Gouny, S; Cozzone, PJ; Girard, N; Koob, M; Le Fur, Y; Ratiney, H; Viola, A; Viout, P | 1 |
| Backes, WH; Edden, RAE; Hofman, PAM; Jansen, JFA; Puts, NAJ; Schram, MT; Stehouwer, CDA; van Boxtel, MPJ; van Bussel, FCG; Wildberger, JE | 1 |
| Downey, LA; McPhee, GM; Noble, A; Stough, C | 1 |
| Karri, V; Kumar, V; Schuhmacher, M | 1 |
| Ambrosius, W; Gazdulska, J; Gołda-Gocka, I; Kozubski, W; Michalak, S; Ramlau, R; Rybacka-Mossakowska, J | 1 |
| Aguilar, K; Fayed, N; Modrego, PJ; Rojas-Salinas, G | 1 |
| Barcikowska, M; Ćwikła, JB; Gabryelewicz, T; Walecki, J | 1 |
| Ait-Ali, D; De Deyn, PP; den Boer, JA; Eiden, LE; Eisel, UL; Engelborghs, S; Luiten, PG; Naudé, PJ; Nyakas, C; van der Heide, R | 1 |
13 review(s) available for glutamic acid and Cognitive Decline
| Article | Year |
|---|---|
Possible Engagement of Nicotinic Acetylcholine Receptors in Pathophysiology of Brain Ischemia-Induced Cognitive Impairment.
Topics: Brain; Brain Ischemia; Cognitive Dysfunction; Glutamic Acid; Humans; Receptors, Nicotinic | 2022 |
Cerebral Glutamate Regulation and Receptor Changes in Perioperative Neuroinflammation and Cognitive Dysfunction.
Topics: Cognitive Dysfunction; Glutamic Acid; Humans; Neuroglia; Neuroinflammatory Diseases; Receptors, N-Methyl-D-Aspartate | 2022 |
Beyond NMDA Receptors: Homeostasis at the Glutamate Tripartite Synapse and Its Contributions to Cognitive Dysfunction in Schizophrenia.
Topics: Cognitive Dysfunction; Glutamic Acid; Homeostasis; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synapses | 2022 |
Glutamatergic neurotransmission: A potential pharmacotherapeutic target for the treatment of cognitive disorders.
Topics: Cognitive Dysfunction; Glutamic Acid; Humans; Prospective Studies; Receptors, Glutamate; Synaptic Transmission | 2023 |
Obsessive-compulsive disorder: Etiology, neuropathology, and cognitive dysfunction.
Topics: Cognitive Dysfunction; Glutamic Acid; Humans; Mental Processes; Obsessive-Compulsive Disorder | 2023 |
Neuropharmacological insight into preventive intervention in posttraumatic epilepsy based on regulating glutamate homeostasis.
Topics: Brain Injuries, Traumatic; Cognitive Dysfunction; Epilepsy, Post-Traumatic; Glutamic Acid; Homeostasis; Humans | 2023 |
The Importance of α-Klotho in Depression and Cognitive Impairment and Its Connection to Glutamate Neurotransmission-An Up-to-Date Review.
Topics: Cognitive Dysfunction; Depression; Depressive Disorder, Major; Glucuronidase; Glutamic Acid; Humans; Synaptic Transmission | 2023 |
The role of glutamate and GABA in cognitive dysfunction in schizophrenia and mood disorders - A systematic review of magnetic resonance spectroscopy studies.
Topics: Brain; Cognitive Dysfunction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Mood Disorders; Schizophrenia | 2022 |
Not Just a Bystander: The Emerging Role of Astrocytes and Research Tools in Studying Cognitive Dysfunctions in Schizophrenia.
Topics: Animals; Astrocytes; Brain; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Neuroglia; Neurons; Schizophrenia | 2021 |
Physiological and pathological processes of synaptic plasticity and memory in drug discovery: Do not forget the dose-response curve.
Topics: Acetylcholine; Animals; Cognitive Dysfunction; Dose-Response Relationship, Drug; Drug Discovery; Drug Therapy, Combination; Glutamic Acid; Humans; Memory; Neuronal Plasticity; Nitric Oxide | 2017 |
PDE Inhibitors for the Treatment of Schizophrenia.
Topics: Antipsychotic Agents; Cognitive Dysfunction; Dopamine; Dopamine D2 Receptor Antagonists; Glutamic Acid; Humans; Phosphodiesterase Inhibitors; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology | 2017 |
Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia.
Topics: Acetylcholine; Animals; Calcium Signaling; Cognitive Dysfunction; Cyclic AMP; GABAergic Neurons; Gene-Environment Interaction; Genetic Predisposition to Disease; Glutamic Acid; Haplorhini; Humans; Interneurons; Memory, Short-Term; Neural Pathways; Prefrontal Cortex; Pyramidal Cells; Schizophrenia; Schizophrenic Psychology; Stress, Psychological | 2018 |
Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain.
Topics: Animals; Arsenic; Binding, Competitive; Cadmium; Calcium; Cognitive Dysfunction; Complex Mixtures; Environmental Pollutants; Glutamic Acid; Heavy Metal Poisoning, Nervous System; Hippocampus; Humans; Lead; Metals, Heavy; Methylmercury Compounds; Models, Biological; Protein Binding; Receptors, N-Methyl-D-Aspartate; Risk Factors; Sodium-Potassium-Exchanging ATPase | 2016 |
1 trial(s) available for glutamic acid and Cognitive Decline
| Article | Year |
|---|---|
Effects of High Definition-Transcranial Direct Current Stimulation on Local GABA and Glutamate Levels Among Older Adults with and without Mild Cognitive Impairment: An Exploratory Study.
Topics: Aged; Cognitive Dysfunction; Double-Blind Method; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Transcranial Direct Current Stimulation | 2021 |
68 other study(ies) available for glutamic acid and Cognitive Decline
| Article | Year |
|---|---|
Reduced GABA levels in the medial prefrontal cortex are associated with cognitive impairment in patients with NMOSD.
Topics: Cognitive Dysfunction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuromyelitis Optica; Prefrontal Cortex | 2022 |
Topics: Aged; Alzheimer Disease; Aspartic Acid; Cognition; Cognitive Dysfunction; Creatine; Glutamic Acid; Humans; Inositol; Proton Magnetic Resonance Spectroscopy | 2022 |
Effects of Donepezil Treatment on Brain Metabolites, Gut Microbiota, and Gut Metabolites in an Amyloid Beta-Induced Cognitive Impairment Mouse Pilot Model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognitive Dysfunction; Disease Models, Animal; Donepezil; Gastrointestinal Microbiome; Glutamic Acid; Glycerol; Hypoxanthines; Inosine; Mice; Oxalates; Phenylalanine; Pyrrolidonecarboxylic Acid; Xylose | 2022 |
Neurochemical and functional reorganization of the cognitive-ear link underlies cognitive impairment in presbycusis.
Topics: Cognition; Cognitive Dysfunction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Presbycusis | 2023 |
Visuo-spatial processing is linked to cortical glutamate dynamics in Parkinson's disease - a 7-T functional magnetic resonance spectroscopy study.
Topics: Cognitive Dysfunction; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Parkinson Disease; Spatial Processing | 2023 |
Mechanism of cognitive impairment induced by d-galactose and l-glutamate through gut-brain interaction in tree shrews.
Topics: Animals; Brain; Cognitive Dysfunction; Galactose; Glutamic Acid; Interleukin-18; Maze Learning; NF-kappa B; Occludin; Toll-Like Receptor 2; Tupaiidae | 2023 |
Neonatal Maternal Separation Induces Sexual Dimorphism in Brain Development: The Influence on Amino Acid Levels and Cognitive Disorders.
Topics: Amino Acids; Animals; Brain; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Hippocampus; Male; Maternal Deprivation; Memory Disorders; Rats; Receptor, Metabotropic Glutamate 5; Sex Characteristics | 2023 |
Addressing the alterations in cerebral ischemia-reperfusion injury on the brain mitochondrial activity: A possible link to cognitive decline.
Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Cognitive Dysfunction; Electron Transport; Glutamic Acid; Male; Mitochondria; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Wistar; Reperfusion Injury | 2019 |
D-glutamate, D-serine, and D-alanine differ in their roles in cognitive decline in patients with Alzheimer's disease or mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Behavioral Symptoms; Chromatography, Liquid; Cognition; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Diet; Female; Glutamic Acid; Hospitals, University; Humans; Male; Middle Aged; Neuropsychological Tests; Serine; Taiwan | 2019 |
Prefrontal GABA and glutamate levels correlate with impulsivity and cognitive function of prescription opioid addicts: A
Topics: Adult; Antitussive Agents; Codeine; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Impulsive Behavior; Male; Middle Aged; Opioid-Related Disorders; Prefrontal Cortex; Prescription Drugs; Proton Magnetic Resonance Spectroscopy | 2020 |
Reduced Hippocampal Glutamate and Posterior Cingulate N-Acetyl Aspartate in Mild Cognitive Impairment and Alzheimer's Disease Is Associated with Episodic Memory Performance and White Matter Integrity in the Cingulum: A Pilot Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognitive Dysfunction; Diffusion Tensor Imaging; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Limbic System; Magnetic Resonance Spectroscopy; Male; Memory, Episodic; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Pilot Projects; White Matter | 2020 |
Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats.
Topics: Affect; alpha-Linolenic Acid; Animals; Behavior, Animal; Cognition; Cognitive Dysfunction; Depression; Diet; Endocannabinoids; Fatty Acids, Unsaturated; Glutamic Acid; Hippocampus; Linoleic Acid; Male; Oleic Acid; Paeonia; Patch-Clamp Techniques; Plant Oils; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sleep Deprivation; Synaptic Transmission | 2020 |
Pananx notoginseng saponins attenuate CCL2-induced cognitive deficits in rats via anti-inflammation and anti-apoptosis effects that involve suppressing over-activation of NMDA receptors.
Topics: AIDS Dementia Complex; Animals; Anti-Inflammatory Agents; Apoptosis; Chemokine CCL2; Cognitive Dysfunction; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; Panax notoginseng; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Saponins; Superoxide Dismutase | 2020 |
Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic Treatment.
Topics: Adult; Antipsychotic Agents; Cognitive Dysfunction; Default Mode Network; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory; Memory, Episodic; Mental Recall; Proton Magnetic Resonance Spectroscopy; Recognition, Psychology; Risperidone; Schizophrenia; Treatment Outcome; Young Adult | 2021 |
Silymarin sex-dependently improves cognitive functions and alters TNF-α, BDNF, and glutamate in the hippocampus of mice with mild traumatic brain injury.
Topics: Animals; Animals, Outbred Strains; Brain Concussion; Brain Injuries; Brain-Derived Neurotrophic Factor; Cognition; Cognitive Dysfunction; Disease Models, Animal; Female; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Mice; Neuroprotective Agents; Oxidative Stress; Sex Factors; Silymarin; Tumor Necrosis Factor-alpha | 2020 |
Knockdown of Follistatin-like 1 disrupts synaptic transmission in hippocampus and leads to cognitive impairments.
Topics: Animals; Cognitive Dysfunction; Follistatin-Related Proteins; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Hippocampus; Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Patch-Clamp Techniques; Synaptic Transmission | 2020 |
Baseline measures of cerebral glutamate and GABA levels in individuals at ultrahigh risk for psychosis: Implications for clinical outcome after 12 months.
Topics: Adolescent; Adult; Brain Chemistry; Cognition; Cognitive Dysfunction; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Neuropsychological Tests; Prognosis; Psychopathology; Psychotic Disorders; Thalamus; Time Factors; Treatment Outcome; Young Adult | 2020 |
Riluzole attenuates glutamatergic tone and cognitive decline in AβPP/PS1 mice.
Topics: Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Glutamic Acid; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Presenilin-1; Riluzole | 2021 |
Hippocampal hyperglutamatergic signaling matters: Early targeting glutamate neurotransmission as a preventive strategy in Alzheimer's disease: An Editorial Highlight for "Riluzole attenuates glutamatergic tone and cognitive decline in AβPP/PS1 mice" on pa
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Glutamic Acid; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Riluzole; Synaptic Transmission | 2021 |
Memantine ameliorates cognitive impairment induced by exposure to chronic hypoxia environment at high altitude by inhibiting excitotoxicity.
Topics: Altitude; Altitude Sickness; Alzheimer Disease; Animals; Cell Death; Cognition; Cognitive Dysfunction; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hypoxia; Male; Memantine; Memory; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2021 |
Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer's disease: Machine learning approaches.
Topics: Aged; Aged, 80 and over; Algorithms; Alzheimer Disease; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Cognitive Dysfunction; Diagnosis, Differential; Female; Glutamic Acid; Humans; Machine Learning; Male; Middle Aged; Psychiatric Status Rating Scales; Sensitivity and Specificity; Severity of Illness Index | 2021 |
Longitudinal tracing of neurochemical metabolic disorders in working memory neural circuit and optogenetics modulation in rats with vascular cognitive impairment.
Topics: Animals; Brain; Brain Ischemia; Choline; Cognitive Dysfunction; Glutamic Acid; Magnetic Resonance Spectroscopy; Memory, Short-Term; Metabolic Diseases; Neural Pathways; Optogenetics; Rats; White Matter | 2021 |
HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis.
Topics: Amyloidosis; Animals; Antibodies, Monoclonal, Humanized; Cholesterol; Cognitive Dysfunction; Diet, High-Fat; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; HMGB1 Protein; Male; Memantine; PCSK9 Inhibitors; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Toll-Like Receptor 4 | 2021 |
Shashen-Maidong Decoction improved chronic intermittent hypoxia-induced cognitive impairment through regulating glutamatergic signaling pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disks Large Homolog 4 Protein; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Hippocampus; Hypoxia; Male; Maze Learning; Memory, Short-Term; Mice, Inbred C57BL; Neuroprotective Agents; ras GTPase-Activating Proteins; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spatial Memory | 2021 |
COVID-19-related cognitive dysfunction may be associated with transient disruption in the DLPFC glutamatergic pathway.
Topics: Adult; Aspartic Acid; Cognitive Dysfunction; COVID-19; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Signal Transduction | 2021 |
High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice.
Topics: Amyloid beta-Peptides; Animals; Behavior Rating Scale; Brain Injuries, Traumatic; Cognition; Cognitive Dysfunction; Electrophysiology; Gene Ontology; Glutamic Acid; Memantine; Mice; Microglia; Multigene Family; Neuronal Plasticity; Neurons; Receptors, N-Methyl-D-Aspartate; Synapses; tau Proteins; Transcriptome | 2021 |
AMPA induced cognitive impairment in rats: Establishing the role of endoplasmic reticulum stress inhibitor, 4-PBA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Butylamines; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Excitatory Amino Acid Agonists; Glutamic Acid; Locomotion; Male; Rats; Rats, Sprague-Dawley | 2021 |
Activation of 5-HT 1b/d receptor restores the cognitive function by reducing glutamate release, deposition of β-amyloid and TLR-4 pathway in the brain of scopolamine-induced dementia in rat.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Brain; Cognition; Cognitive Dysfunction; Dementia; Disease Models, Animal; Glutamic Acid; Glutathione; Glutathione Peroxidase; Maze Learning; Memory Disorders; Oxazolidinones; Oxidative Stress; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Scopolamine; Serotonin; Serotonin 5-HT1 Receptor Agonists; Superoxide Dismutase; Toll-Like Receptor 4; Tryptamines | 2021 |
Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats.
Topics: Animals; Cognitive Dysfunction; Dementia, Multi-Infarct; Disease Models, Animal; Drugs, Chinese Herbal; Glutamic Acid; Male; Memory Disorders; Mitochondria; Neurons; Patched-1 Receptor; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Comprehensive metabolomics profiling reveals common metabolic alterations underlying the four major non-communicable diseases in treated HIV infection.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Atherosclerosis; Cognitive Dysfunction; Female; Glutamic Acid; Glutamine; Glycerophospholipids; HIV Infections; Humans; Liver Cirrhosis; Male; Metabolome; Middle Aged; Plasmalogens; Renal Insufficiency | 2021 |
Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice.
Topics: Amyloid beta-Protein Precursor; Animals; Cognitive Dysfunction; Electroencephalography; Epilepsy; Female; Glutamic Acid; Hippocampus; Homeostasis; Kainic Acid; Long-Term Potentiation; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Plaque, Amyloid; Presenilin-1 | 2021 |
Decreased Glutamate Levels in Patients with Amnestic Mild Cognitive Impairment: An sLASER Proton MR Spectroscopy and PiB-PET Study.
Topics: Aged; Aged, 80 and over; Amnesia; Brain; Cognitive Dysfunction; Female; Glutamic Acid; Humans; Male; Positron-Emission Tomography; Proton Magnetic Resonance Spectroscopy | 2017 |
Effects of Aged Garlic Extract on Cholinergic, Glutamatergic and GABAergic Systems with Regard to Cognitive Impairment in Aβ-Induced Rats.
Topics: Acetylcholine; Amyloid beta-Peptides; Animals; Cholinergic Neurons; Cognitive Dysfunction; gamma-Aminobutyric Acid; Garlic; Gene Expression Regulation; Glutamate Decarboxylase; Glutamic Acid; Hippocampus; Male; Maze Learning; Plant Extracts; Rats; Rats, Wistar; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2017 |
(S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Cerebrovascular Circulation; Cognitive Dysfunction; Dementia, Vascular; Disease Models, Animal; Glutamic Acid; Glutamine; Male; Neurons; Neuroprotective Agents; Nootropic Agents; Pyrrolidines; Rats; Rats, Wistar; Spatial Learning; Spatial Memory; Stereoisomerism; White Matter | 2017 |
Neuroprotection by chotosan, a Kampo formula, against glutamate excitotoxicity involves the inhibition of GluN2B-, but not GluN2A-containing NMDA receptor-mediated responses in primary cultured cortical neurons.
Topics: Animals; Cell Death; Cells, Cultured; Chitosan; Cognitive Dysfunction; Dementia, Vascular; Glutamic Acid; Ischemic Attack, Transient; Medicine, Kampo; Mice; Neurons; Neuroprotective Agents; Phytotherapy; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2017 |
7T Proton Magnetic Resonance Spectroscopy of the Anterior Cingulate Cortex in First-Episode Schizophrenia.
Topics: Adult; Aspartic Acid; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult | 2019 |
Maternal overnutrition leads to cognitive and neurochemical abnormalities in C57BL/6 mice.
Topics: Animals; Aspartic Acid; Avoidance Learning; Brain Chemistry; Cognitive Dysfunction; Diet, High-Fat; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Maternal Nutritional Physiological Phenomena; Memory, Short-Term; Mice, Inbred C57BL; Overnutrition; Prepulse Inhibition; Taurine | 2019 |
Impact of amyloid-beta changes on cognitive outcomes in Alzheimer's disease: analysis of clinical trials using a quantitative systems pharmacology model.
Topics: Algorithms; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Clinical Trials as Topic; Cognition; Cognitive Dysfunction; Computer Simulation; Disease Progression; Glutamic Acid; Humans; Models, Neurological; Muscarinic Antagonists; Peptide Fragments; Scopolamine; Synaptic Transmission; Treatment Outcome | 2018 |
Effect of pioglitazone and simvastatin in lipopolysaccharide-induced amyloidogenesis and cognitive impairment in mice: possible role of glutamatergic pathway and oxidative stress.
Topics: Amyloid beta-Peptides; Animals; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamic Acid; Lipopolysaccharides; Male; Maze Learning; Mice; Neuroprotective Agents; Nitrates; Oxidative Stress; Peptide Fragments; Pioglitazone; Recognition, Psychology; Signal Transduction; Simvastatin | 2019 |
PQQ ameliorates D-galactose induced cognitive impairments by reducing glutamate neurotoxicity via the GSK-3β/Akt signaling pathway in mouse.
Topics: Animals; Cognitive Dysfunction; Cytosol; Galactose; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunologic Factors; Mice; Oncogene Protein v-akt; PQQ Cofactor; Quinones; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2018 |
Hippocampal metabolites in asthma and their implications for cognitive function.
Topics: Adolescent; Adult; Aspartic Acid; Asthma; Cognition; Cognitive Dysfunction; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Young Adult | 2018 |
Glutamate-sensitive imaging and evaluation of cognitive impairment in multiple sclerosis.
Topics: Adult; Cerebral Cortex; Cognitive Dysfunction; Female; Glutamic Acid; Gray Matter; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; White Matter | 2019 |
Melatonin improves vascular cognitive impairment induced by ischemic stroke by remyelination via activation of ERK1/2 signaling and restoration of glutamatergic synapses in the gerbil hippocampus.
Topics: Animals; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cell Death; Cognitive Dysfunction; Gerbillinae; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; MAP Kinase Signaling System; Melatonin; Models, Animal; Myelin Sheath; Neurons; Oligodendroglia; Remyelination; Stroke; Synapses | 2018 |
Novel Blood Biomarkers that Correlate with Cognitive Performance and Hippocampal Volumetry: Potential for Early Diagnosis of Alzheimer's Disease.
Topics: Aged; Alzheimer Disease; Amino Acids; Apolipoproteins E; Biomarkers; Blotting, Western; Case-Control Studies; Cognition; Cognitive Dysfunction; Early Diagnosis; Female; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Mental Status and Dementia Tests; Neuroimaging; Organ Size; Tandem Mass Spectrometry; Transaminases | 2019 |
Molecular mechanism of tuberoinfundibular peptide of 39 on glucocorticoid receptor mediated glutamate/GABA imbalance and cerebral abnormalities against cognitive deficit model.
Topics: Animals; Cognitive Dysfunction; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Neuropeptides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Psychological | 2019 |
Effect of newer anti-epileptic drugs (AEDs) on the cognitive status in pentylenetetrazol induced seizures in a zebrafish model.
Topics: Acetylcholine; Animals; Anticonvulsants; Brain; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Drug Interactions; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Locomotion; Maze Learning; Neuropeptide Y; Pentylenetetrazole; Seizures; Zebrafish | 2019 |
Tooth loss causes spatial cognitive impairment in rats through decreased cerebral blood flow and increased glutamate.
Topics: Animals; Apoptosis; Cerebrovascular Circulation; Cognitive Dysfunction; Glutamic Acid; Hippocampus; Maze Learning; Rats; Tooth Loss | 2019 |
Glutamatergic response to a low load working memory paradigm in the left dorsolateral prefrontal cortex in patients with mild cognitive impairment: a functional magnetic resonance spectroscopy study.
Topics: Aged; Cognitive Dysfunction; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Middle Aged; Oxygen; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy | 2020 |
Protein kinase C is involved in the neuroprotective effect of berberine against intrastriatal injection of quinolinic acid-induced biochemical alteration in mice.
Topics: Animals; Berberine; Cognitive Dysfunction; Disease Models, Animal; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Male; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Protein Kinase C; Quinolinic Acid; Signal Transduction | 2019 |
Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by
Topics: Aging; Anesthesia; Animals; Anxiety; Aspartic Acid; Brain; Cerebral Cortex; Cognitive Dysfunction; Female; Glutamic Acid; Hippocampus; Isoflurane; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Proton Magnetic Resonance Spectroscopy | 2020 |
Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.
Topics: Animals; Benzothiazoles; Brain Injuries; Cell Death; Cell Line; Cell Survival; Cognitive Dysfunction; Dentate Gyrus; Glutamic Acid; Humans; Male; Maze Learning; Mice; Neurons; Oxidative Stress; Primary Cell Culture; Rats; Toluene; Tumor Suppressor Protein p53 | 2013 |
Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arachidonic Acid; Biomarkers; Chromatography, Liquid; Cognitive Dysfunction; Cytidine; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Thymine | 2014 |
Posterior cingulate γ-aminobutyric acid and glutamate/glutamine are reduced in amnestic mild cognitive impairment and are unrelated to amyloid deposition and apolipoprotein E genotype.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Apolipoproteins E; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Genotype; Glutamic Acid; Gyrus Cinguli; Humans; Male; Neurotransmitter Agents | 2015 |
Decreased glial and synaptic glutamate uptake in the striatum of HIV-1 gp120 transgenic mice.
Topics: Animals; Cognitive Dysfunction; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Male; Mice; Mice, Transgenic; Neuroglia; Neurons; Organ Specificity; Synapses; Transgenes | 2016 |
Co-administration of 3-Acetyl-11-Keto-Beta-Boswellic Acid Potentiates the Protective Effect of Celecoxib in Lipopolysaccharide-Induced Cognitive Impairment in Mice: Possible Implication of Anti-inflammatory and Antiglutamatergic Pathways.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Celecoxib; Cognitive Dysfunction; Cyclooxygenase 2 Inhibitors; Drug Combinations; Drug Synergism; Glutamic Acid; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Mice; Triterpenes; Tumor Necrosis Factor-alpha | 2016 |
Glutamine and Glutamate Complex, as Measured by Functional Magnetic Resonance Spectroscopy, Alters During Face-Name Association Task in Patients with Mild Cognitive Impairment and Alzheimer's Disease.
Topics: Adult; Aged; Alzheimer Disease; Brain; Brain Mapping; Cognitive Dysfunction; Cohort Studies; Face; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Names; Neuropsychological Tests; Pattern Recognition, Physiological; ROC Curve | 2016 |
Protective effect of citicoline against aluminum-induced cognitive impairments in rats.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Avoidance Learning; Behavior, Animal; Chlorides; Cognitive Dysfunction; Cytidine Diphosphate Choline; Environmental Pollutants; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Lipid Peroxidation; Male; Maze Learning; Memory, Short-Term; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Nootropic Agents; Oxidative Stress; Rats, Wistar | 2017 |
Polygalasaponin XXXII, a triterpenoid saponin from Polygalae Radix, attenuates scopolamine-induced cognitive impairments in mice.
Topics: Animals; Avoidance Learning; Cerebral Cortex; Cognitive Dysfunction; Dentate Gyrus; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Long-Term Potentiation; Male; Maze Learning; Mice; Neurons; Neuroprotective Agents; Polygala; Primary Cell Culture; Protein-Tyrosine Kinases; Rats; Saponins; Scopolamine; Triterpenes | 2016 |
Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms.
Topics: Animals; Brain Concussion; Cholinergic Agents; Cholinesterase Inhibitors; Cognitive Dysfunction; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Lipid Peroxidation; Maze Learning; Mice; Neurons; Oxidative Stress; Physostigmine | 2016 |
Postnatal Isoflurane Exposure Induces Cognitive Impairment and Abnormal Histone Acetylation of Glutamatergic Systems in the Hippocampus of Adolescent Rats.
Topics: Acetylation; Animals; Butyric Acid; Cognitive Dysfunction; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Histone Deacetylase 2; Histones; Isoflurane; Male; Maze Learning; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2016 |
The pathogenic mechanism of dysbindin-1B toxic aggregation: BLOC-1 and intercellular vesicle trafficking.
Topics: Animals; Brain; Cells, Cultured; Cognitive Dysfunction; Dysbindin; Dystrophin-Associated Proteins; Endocytosis; Glutamic Acid; Humans; Intracellular Space; Maze Learning; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Protein Aggregation, Pathological; RNA, Messenger; Synaptic Vesicles | 2016 |
Creatine, Glutamine plus Glutamate, and Macromolecules Are Decreased in the Central White Matter of Premature Neonates around Term.
Topics: Cognitive Dysfunction; Creatine; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Glutamine; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Occipital Lobe; Proton Magnetic Resonance Spectroscopy; Retrospective Studies; Taurine; Temporal Lobe; Term Birth; Thalamus; White Matter | 2016 |
Increased GABA concentrations in type 2 diabetes mellitus are related to lower cognitive functioning.
Topics: Aged; Blood Glucose; Case-Control Studies; Cognition; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycated Hemoglobin; Gray Matter; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; White Matter | 2016 |
Cognitive training and Bacopa monnieri: Evidence for a combined intervention to alleviate age associated cognitive decline.
Topics: Aged; Animals; Bacopa; Brain; Cognition; Cognitive Dysfunction; Glutamic Acid; Hippocampus; Humans; Medicine, Ayurvedic; Memory; Models, Theoretical; Phytotherapy; Plant Extracts; Rats; Synapses; Up-Regulation | 2016 |
The Markers of Glutamate Metabolism in Peripheral Blood Mononuclear Cells and Neurological Complications in Lung Cancer Patients.
Topics: Aged; Biomarkers; Carcinoma, Non-Small-Cell Lung; Cognitive Dysfunction; Female; Glutamate Decarboxylase; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Humans; Lung Neoplasms; Male; Middle Aged; Monocytes | 2016 |
Brain glutamate levels are decreased in Alzheimer's disease: a magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Severity of Illness Index | 2011 |
N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Temporal Lobe | 2011 |
Lipocalin 2: novel component of proinflammatory signaling in Alzheimer's disease.
Topics: Acute-Phase Proteins; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Base Sequence; Brain; Case-Control Studies; Cells, Cultured; Cognitive Dysfunction; Female; Gene Expression; Glutamic Acid; Humans; Inflammation Mediators; Lipocalin-2; Lipocalins; Male; Mice; Models, Neurological; Neurons; Oligonucleotide Array Sequence Analysis; Oncogene Proteins; Proto-Oncogene Proteins; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2012 |