glutamic acid has been researched along with Cognition Disorders in 155 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (5.16) | 18.2507 |
| 2000's | 42 (27.10) | 29.6817 |
| 2010's | 99 (63.87) | 24.3611 |
| 2020's | 6 (3.87) | 2.80 |
| Authors | Studies |
|---|---|
| Birling, MC; Brault, V; Flores-Gutiérrez, J; Garbis, SD; Hérault, Y; Iacono, G; Lalanne, V; Lindner, L; Manousopoulou, A; Meziane, H; Nguyen, TL; Pavlovic, G; Selloum, M; Sorg, T; Yu, E | 1 |
| Bajaj, P; Kalotra, S; Kaur, G; Sharma, A; Singh, H | 1 |
| Bie, B; Foss, JF; Naguib, M; Wu, J | 1 |
| Chang, CY; Hsieh, YC; Kuo, MC; Lai, WS; Luo, DZ; Pei, JC | 1 |
| Liu, DS; Song, YN; Wang, HY; Wang, SP; Wang, Y; Zhang, JB; Zhu, CH | 1 |
| Kalita, J; Kumar, V; Misra, UK; Parashar, V | 1 |
| Alonso, JF; Baena, A; Duque, JE; Hernández, AM; Lopera, F; Mañanas, MA; Ochoa, JF; Tobón, CA | 1 |
| Gong, QY; Gu, GJ; Guo, Y; Liu, JH; Wang, MY; Xu, JR; Zhang, B; Zhang, Q; Zhang, W | 1 |
| Caetano, I; Correia, JS; Guerra-Gomes, S; Martins, M; Oliveira, JF; Pinto, L; Reis, JS; Sardinha, VM; Sousa, N; Tavares, G; Teixeira-Castro, A | 1 |
| Brunovský, M; Horáček, J; Polák, J; Vlček, P | 1 |
| Wei, J; Yan, Z; Yuen, EY | 1 |
| Aarts, E; Buitelaar, JK; Hartman, CA; Hoekstra, PJ; Lythgoe, DJ; Naaijen, J; Zwiers, MP | 1 |
| Jia, L; Liu, B; Ma, J; Qi, X; Shan, Y; Wang, H; Wu, W; Zhou, H | 1 |
| Hu, Y; Liu, M; Liu, MY; Liu, P; Yan, JJ; Yu, BY; Zhang, GQ; Zhou, XJ | 1 |
| Diwan, PV; Kakalij, RM; Prasad, VV; Singh, HJ; Syeda, TU | 1 |
| Figuera-Losada, M; Potter, MC; Rojas, C; Slusher, BS | 1 |
| Abraham, WC; Hulme, SR; Jones, OD | 1 |
| Ahluwalia, V; Bajaj, JS; Bouneva, I; Fuchs, M; Gilles, H; Heuman, DM; Kraft, KA; Luketic, V; Puri, P; Sanyal, AJ; Sterling, RK; Stravitz, RT; Thacker, L; Wade, JB | 1 |
| Bolo, NR; Francis, AN; Keshavan, MS; Mathew, IT; Sanghavi, K; Stanley, JA; Tandon, N | 1 |
| Pehrson, AL; Sanchez, C | 1 |
| Carvalho, FB; DA Rosa, MM; DA Silva, AS; DA Silva, CB; DA Souza, AC; Gai, BM; Lopes, ST; Mazzanti, CM; Monteiro, SG; Nogueira, CW; Paim, FC; Pereira, PR; Rubin, MA; Wolkmer, P | 1 |
| Adlard, PA; Bray, L; Bush, AI; Cherny, RA; Doble, P; Finkelstein, DI; Gunawan, L; Hare, D; Lear, J; Sedjahtera, A | 1 |
| Snyder, GL; Vanover, KE | 1 |
| Jiang, R; Si, D; Wang, H; Yang, P; Zhang, Y; Zhou, H | 1 |
| Fan, Y; Gao, Y; Liu, X; Sun, D; Wu, G; Yan, Y; Zeng, J; Zhang, J | 1 |
| Dong, Y; Feng, D; Gao, G; Huang, J; Ma, Y; Qin, H; Wang, W; Wu, L; Wu, S; Zhang, Z | 1 |
| Beer, R; Benke, T; Bodner, T; Delazer, M; Fischer, M; Hackl, W; Helbok, R; Humpel, C; Lackner, P; Pfausler, B; Schiefecker, A; Schmutzhard, E; Sohm, F; Stover, JF; Thomé, C | 1 |
| Craven, AR; Falkenberg, LE; Hugdahl, K; Johnsen, E; Kroken, RA; L Berg, EM; Specht, K; Westerhausen, R | 1 |
| Dierssen, M; Molas, S | 1 |
| Gargiulo, PÁ; Landa De Gargiulo, AI | 1 |
| Andrés, E; Fayed, N; Garcia-Campayo, J; Modrego, PJ; Viguera, L | 1 |
| Cheng, Y; Duan, Y; Fan, R; He, Y; Sun, G; Sun, X; Wang, Z; Zhang, H | 1 |
| Gao, X; He, R; Hui, Y; Jin, J; Li, J; Li, L; Li, S; Li, Y; Luo, S; Ma, N; Peng, Y; Tang, L; Wang, D; Zhang, S; Zhou, Y | 1 |
| Daskalakis, ZJ; Graff-Guerrero, A; Price, R; Rajji, TK; Salavati, B; Sun, Y | 1 |
| Hascup, ER; Hascup, KN | 1 |
| Barati, M; Homberg, JR; Khojasteh, F; Mehrpouya, S; Mirzamohammadi, S; Nahavandi, A; Raufi, S; Soleimani, M | 1 |
| Agusti, A; Balzano, T; Belghiti, M; Cabrera-Pastor, A; Dadsetan, S; Felipo, V; Garcia-Garcia, R; Gomez-Gimenez, B; Hernandez-Rabaza, V; Llansola, M; Malaguarnera, M; Montoliu, C; Taoro, L | 1 |
| Baqi, Y; Batalha, VL; Blum, D; Buée, L; Burnouf, S; Coelho, JE; D'Hooge, R; Faivre, E; Ferry, B; Flaten, V; Hamdane, M; Humez, S; Laurent, C; Ledent, C; Lopes, LV; Malik, E; Mariciniak, E; Müller, CE; Parrot, S; Sergeant, N; Van der Jeugd, A | 1 |
| Dal-Cim, TA; de Oliveira, KA; dos Santos, AA; dos Santos, VV; Farina, M; Martins, WC; Mendes-de-Aguiar, CB; Prediger, RD; Tasca, CI; Vandresen-Filho, S; Viola, GG | 1 |
| Agostinho, P; Augusto, E; Boison, D; Chen, JF; Cunha, RA; Matos, M; Shen, HY; Wang, Y; Wang, YT; Wei, CJ | 1 |
| Chiu, SL; Huganir, RL; Sharma, K; Volk, L | 1 |
| Correll, CU; Zink, M | 1 |
| Brennan, BP; Hudson, JI; Janes, AC; Jensen, JE; Kanayama, G; Kaufman, MJ; Kerrigan, AR; Pope, HG | 1 |
| Aoyama, Y; Hattori, T; Hiramatsu, M; Kim, HC; Mamiya, T; Mouri, A; Nabeshima, T; Nagai, T; Sakakibara, N; Shimato, A; Soh, Y; Toriumi, K; Ueda, E; Yamada, K | 1 |
| Gerhardt, GA; Hickman, JE; Hunsberger, HC; Libell, EM; Reed, MN; Rudy, CC; Speer, RR; Weitzner, DS | 1 |
| Furukawa-Hibi, Y; Hattori, H; Hibi, H; Mita, T; Takeuchi, H; Ueda, M; Yamada, K; Yamamoto, A | 1 |
| Hood, RL; Meshul, CK; Mitchell, SH; Pflibsen, L; Sconce, MD; Stang, KA; Wilson, VB | 1 |
| Arima, H; Fujisawa, H; Fukumoto, K; Hayashi, Y; Iwama, S; Izumida, H; Kiyota, A; Komatsu, Y; Mizoguchi, H; Murata, Y; Nakashima, K; Ochiai, H; Oiso, Y; Sugimura, Y; Takagi, H; Takagishi, Y; Takeuchi, H; Takeuchi, S | 1 |
| Agius, M; Conci, E | 1 |
| Danese, S; Gupta, RK; Haris, M; Marincola, FM; Rangan, M; Rutella, S; Saraswat, VA; Thomas, MA; Wang, E; Yadav, SK | 1 |
| Molnár, E; Whitcomb, DJ | 1 |
| Mayanagi, T; Sobue, K; Yasuda, H | 1 |
| Datusalia, AK; Sharma, SS | 1 |
| Huang, L; Huang, Y; Jiang, H; Li, F; Li, H; Li, L; Li, X; Xiao, J; Yang, L; Yang, T | 1 |
| Blokhuis, C; Caan, MWA; Cohen, S; Kootstra, NA; Kuhle, J; Kuijpers, TW; Majoie, CBLM; Pajkrt, D; Reiss, P; Scherpbier, HJ; Ter Stege, JA; Teunissen, CE; Van Dalen, YW | 1 |
| Batassini, C; Dutra, MF; Galland, F; Gonçalves, CA; Guerra, MC; Hansen, F; Leite, MC; Pandolfo, P; Torres, FV | 1 |
| Takeda, A; Tamano, H | 1 |
| Adlard, PA; Bush, AI; Ide, K; Takeda, A; Tamano, H | 1 |
| Guo, J; Ming, D; Wang, F; Wang, L; Wang, Z; Yang, C; Yang, J; Yang, Z; Yao, Y | 1 |
| Bu, L; Chen, L; Chen, S; Dang, H; Li, Y; Liu, X; Lu, C; Pan, R; Qu, L; Shi, Z; Sun, L; Sun, X | 1 |
| Bates, R; Jiao, HF; Li, BM; Li, L; Liu, F; Mei, L; Patel, M; Stranahan, AM; Sun, XD; Wang, SQ; Xiong, L; Xiong, MT; Xiong, WC; Zhang, HS; Zhang, L | 1 |
| An, L; Sun, W | 1 |
| Akinyemi, A; Michel, G; Sanchez-Gonzalez, MA; Sterkel, S | 1 |
| Abdel-Rahman, E; Ahuja, M; Amin, R; Buabeid, M; Dhanasekaran, M; Majrashi, M; Parameshwaran, K; Pondugula, S; Ramesh, S; Suppiramaniam, V; Thiruchelvan, K | 1 |
| Cens, T; Charnet, P; Leyris, JP | 1 |
| Bell, KF; Cuello, AC | 1 |
| Bohn, L; de Almeida, LM; Degerone, D; Gonçalves, CA; Gottfried, C; Leite, MC; Nardin, P; Netto, CA; Pimentel, A; Rodrigues, L; Scornavaca, F; Souza, DO; Swarowsky, A; Vicente, E | 1 |
| Javitt, DC | 1 |
| Doezema, D; Elgie, R; Gasparovic, C; Ling, J; Mannell, M; Mayer, AR; Phillips, J; Yeo, R | 1 |
| Howe, WM; Parikh, V; Sarter, M | 1 |
| Freund, HJ; Klosterkoetter, J; Kuhn, J; Lenartz, D; Mai, JK; Schnell, T; Sturm, V | 1 |
| Aarsland, D; Alves, G; Ballard, C; Bostrom, F; Kossakowski, K; Leroi, I; Londos, E; Minthon, L; Pozo-Rodriguez, F; Walker, Z | 1 |
| Tan, HY | 1 |
| Borisova, TA; Krisanova, NV; Trikash, IO | 1 |
| Bolo, N; Jacobson, AM; Kim, JE; Lyoo, IK; Musen, G; Renshaw, PF; Ryan, CM; Simonson, DC; Weinger, K; Yoon, SJ | 1 |
| Chattarji, S; Diamond, DM; Fuchs, E; Jay, TM; McEwen, BS; Reagan, LP; Svenningsson, P | 1 |
| Gołembiowska, K; Nikiforuk, A; Popik, P | 1 |
| Boulanger, Y; Ellemberg, D; Henry, LC; Lassonde, M; Tremblay, S | 1 |
| Abdul, HM; Baig, I; Beckett, TL; Furman, JL; Kraner, SD; LeVine, H; Mathis, DM; Murphy, MP; Norris, CM; Patel, ES; Sama, MA; Weidner, AM | 1 |
| Cohen, AS; Cole, JT; Elkind, JA; Kundu, S; Mitala, CM; Nissim, I; Verma, A | 1 |
| O'Tuathaigh, CM; Waddington, JL | 1 |
| Ali, F; Cavanna, AE; McCorry, D; Rickards, HE | 1 |
| de Freitas-Silva, DM; Franco, GC; Pereira, SR; Resende, Lde S; Ribeiro, AM | 1 |
| Howland, RH | 1 |
| Kiess, W; Klammt, J; Kratzsch, J; Kruis, T; Müller, E; Pfäffle, R; Schlicke, M; Schmidt, G; van de Leur, HS; Wallborn, T; Wüller, S | 1 |
| Gallinat, J; Joppke, M; Klär, AA; Schubert, F; Westhoff, TH; Wirth, C; Zidek, W | 1 |
| Barker, PB; Mohamed, MA; Moxley, RT; Pomper, MG; Sacktor, NC; Selnes, OA; Skolasky, RL | 1 |
| Baig, I; Guttmann, RP; Levine, H; Mohmmad Abdul, H; Norris, CM | 1 |
| Apfeldorf, W; Bustillo, JR; Caprihan, A; Chen, H; Gasparovic, C; Lauriello, J; Mullins, P; Posse, S; Qualls, C | 1 |
| Buchthal, S; Chang, L; Ernst, T; Jiang, CS; Nakama, H | 1 |
| Calcagno, E; Carli, M; Invernizzi, RW; Mainini, E; Mainolfi, P | 1 |
| Gonzales, MM; Goudarzi, K; Haley, AP; Miles, SC; Tanaka, H; Tarumi, T | 1 |
| Bergerot, D; Caudal, D; Godsil, BP; Jay, TM; Mailliet, F | 1 |
| Laroche, S; Miranda, R; Nudel, U; Vaillend, C | 1 |
| Falkai, P; Gruber, O; Schmitt, A; Yeganeh-Doost, P | 1 |
| Ali, N; Cole, PD; Gulinello, M; Vijayanathan, V | 1 |
| Batassini, C; Bernardi, C; Biasibetti, R; Costa, AP; Gonçalves, CA; Leal, RB; Lopes, MW; Tortorelli, LS; Tramontina, AC; Wartchow, KM | 1 |
| Chen, X; Fang, F; Huang, T; Luddy, JS; Lue, LF; Yan, SS | 1 |
| Alexander, KS; Bruno, JP; Schwarcz, R; Wu, HQ | 1 |
| Della Sala, S; Lopera, F; MacPherson, SE; Moreno, S; Parra, MA | 1 |
| Graybeal, C; Holmes, A; Kiselycznyk, C | 1 |
| Bustamante, ML; Gaspar, PA; Martinez, A; Rojo, LE | 1 |
| Bhadania, M; Joshi, H; Kulkarni, VH; Patel, P | 1 |
| Brunt, TM; McMaster, MT; Niesink, RJ; van Amsterdam, JG | 1 |
| Gonzalez-Burgos, G; Lewis, DA | 1 |
| Aldinger, KA; Ashwood, P; Bauman, ML; Blaha, CD; Blatt, GJ; Chauhan, A; Chauhan, V; Dager, SR; Dickson, PE; Estes, AM; Fatemi, SH; Goldowitz, D; Heck, DH; Kemper, TL; King, BH; Martin, LA; Millen, KJ; Mittleman, G; Mosconi, MW; Persico, AM; Sweeney, JA; Webb, SJ; Welsh, JP | 1 |
| Bruno, JP; Elmer, GI; Pocivavsek, A; Schwarcz, R; Wu, HQ | 1 |
| Femenía, T; Gómez-Galán, M; Lindskog, M; Magara, S | 1 |
| Barker, PB; Bassett, SS; Brandt, J; Carass, A; Edden, RA; Liu, X; Margolis, RL; Oishi, K; Redgrave, GW; Ross, CA; Shanahan, M; Unschuld, PG; van Zijl, PC; Wang, X | 1 |
| Adachi, Y; Aleksic, B; Banno, M; Hashimoto, R; Iidaka, T; Ikeda, M; Inada, T; Iwata, N; Kawano, N; Kikuchi, T; Kohmura, K; Koide, T; Kushima, I; Nakamura, Y; Ohi, K; Okada, T; Ozaki, N; Suzuki, M; Takeda, M; Ujike, H; Yamashita, S; Yasuda, Y | 1 |
| Bechi, M; Benedetti, F; Bosia, M; Bramanti, P; Cavallaro, R; Cocchi, F; Lorenzi, C; Pirovano, A; Smeraldi, E; Spangaro, M; Zanoletti, A | 1 |
| Eagan, DE; Gonzales, MM; Haley, AP; Tanaka, H; Tarumi, T; Vaghasia, M | 1 |
| Ahluwalia, V; Bajaj, JS; Bouneva, I; Fuchs, M; Gilles, H; Heuman, DM; Kraft, KA; Luketic, V; Monteith, P; Noble, NA; Puri, P; Sanyal, AJ; Sterling, RK; Stravitz, RT; Wade, JB; White, MB | 1 |
| Bermúdez-Rattoni, F; Castro-Cruz, M; Guzmán-Ramos, K; LaFerla, FM; Martínez-Coria, H; McGaugh, JL; Moreno-Castilla, P | 1 |
| Agustí, A; Cabrera-Pastor, A; Cauli, O; Felipo, V; Giménez-Garzó, C; González-Usano, A; Hernández-Rabaza, V; Llansola, M; Montoliu, C | 1 |
| Afinowi, NO; Bussey, TJ; Coba, MP; Elsegood, KA; Fricker, DG; Grant, SG; Indersmitten, T; Komiyama, NH; Kopanitsa, MV; Nithianantharajah, J; O'Dell, TJ; Saksida, LM; Skene, NG; Stanford, LE; Tuck, EJ | 1 |
| Bai, Z; Li, M; Liu, F; Liu, X; Song, G; Xu, J; Zhang, Q | 1 |
| Choi, SH; Jeong, SJ; Kim, HS; Koo, JW; Park, CH; Seo, JH; Suh, YH | 1 |
| Enyu, L; Hongmin, B; Xiang, Z; Zhou, F | 1 |
| Baxter, MG; Nicolle, MM | 1 |
| Chen, SJ; Chen, WF; Huang, LT; Lai, MC; Lin, SZ; Tao, PL; Wang, CL; Yang, CH; Yang, SN | 1 |
| Bartrés-Faz, D; Clemente, IC; González-Pérez, E; Junqué, C; Matarín, M; Moral, P; Moya, A; Solé-Padullés, C; Via, M | 1 |
| Castner, SA; Goldman-Rakic, PS; Williams, GV | 1 |
| Gorman, J; Simon, A | 1 |
| Jahanshahi, M; Limousin-Dowsey, P; Silberstein, P; Tisch, S | 1 |
| Jann, MW | 1 |
| Boulay, LJ; Chouinard, S; Stip, E | 1 |
| Antonucci, F; Bozzi, Y; Caleo, M; Costantin, L; Funicello, M; Gobbi, M; Maffei, L; Mennini, T; Montecucco, C; Richichi, C; Rossetto, O; Vezzani, A; Viegi, A | 1 |
| Hertel, P; Jardemark, KE; Langlois, X; Marcus, MM; Svensson, TH; Wadenberg, ML | 1 |
| Baumgartner, WA | 1 |
| Cerhan, J; Stewart, CA | 1 |
| Gallagher, M; Kirkwood, A; Lee, HK; Min, SS | 1 |
| Arciniegas, DB; Silver, JM | 1 |
| Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pedersen, A; Pfleiderer, B; Rothermundt, M; Siegmund, A; Spitzberg, K; Suslow, T | 1 |
| Lewis, DA; Moghaddam, B | 1 |
| Ayuyao, N; Cook, EH; Grieve, A; Guter, S; Leventhal, BL; Owley, T; Salt, J; Walton, L | 1 |
| Chappell, AS; Gonzales, C; Mohs, RC; Sperling, R; Williams, J; Witte, MM | 1 |
| Büchert, M; Ebert, D; Hennig, J; Olbrich, HM; Rüsch, N; Tebartz van Elst, L; Thiel, T; Valerius, G | 1 |
| Bell, KF; Bennett, DA; Cuello, AC | 1 |
| Mayer, D; Pfefferbaum, A; Sullivan, EV; Zahr, NM | 1 |
| Hanstock, CC; Purdon, SE; Seres, P; Tibbo, P; Valiakalayil, A | 1 |
| Erol, DD; Ibis, HA | 1 |
| Francis, PT | 1 |
| de Leon, MJ; De Santi, S; Glodzik, L; Gonen, O; King, KG; Liu, S | 1 |
| Hyvönen, M; Lahtinen, H; Miettinen, R; Riekkinen, PJ; Sirviö, J; Ylinen, A | 1 |
| Tollefson, GD | 1 |
| Das, I; de Belleroche, J; Garey, LJ; Hirsch, SR | 1 |
| Kosten, TR | 1 |
| Lynch, MA | 1 |
| Raber, J | 1 |
| Breier, A | 1 |
| Greene, RW; Grunze, H; Hirayasu, Y; McCarley, RW; Nestor, PG; Niznikiewicz, MA; O'Donnell, BF; Salisbury, DF; Shenton, ME | 1 |
| Gerlach, M; Heim, C; Kurz, T; Lan, J; Riederer, P; Sieklucka, M; Sontag, KH; Zhang, J | 1 |
| Nakamura, K | 1 |
45 review(s) available for glutamic acid and Cognition Disorders
| Article | Year |
|---|---|
Not Just a Bystander: The Emerging Role of Astrocytes and Research Tools in Studying Cognitive Dysfunctions in Schizophrenia.
Topics: Animals; Astrocytes; Brain; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Glutamic Acid; Humans; Neuroglia; Neurons; Schizophrenia | 2021 |
Molecular and Epigenetic Mechanisms for the Complex Effects of Stress on Synaptic Physiology and Cognitive Functions.
Topics: Animals; Cognition Disorders; Epigenesis, Genetic; Glutamic Acid; Humans; Stress, Psychological; Synapses; Synaptic Transmission | 2017 |
Targeting the glutamatergic system for the treatment of HIV-associated neurocognitive disorders.
Topics: AIDS Dementia Complex; Animals; Cognition Disorders; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Glutamic Acid; HIV Infections; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Treatment Outcome | 2013 |
Emerging roles of metaplasticity in behaviour and disease.
Topics: Animals; Behavior; Behavior, Animal; Cognition Disorders; Conditioning, Classical; Gene Expression Regulation; Glutamic Acid; Humans; Learning; Memantine; Memory; Mice; Models, Neurological; Models, Psychological; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuronal Plasticity; Nootropic Agents; Rats; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stroke; Time Factors; Transcranial Magnetic Stimulation; Up-Regulation | 2013 |
Serotonergic modulation of glutamate neurotransmission as a strategy for treating depression and cognitive dysfunction.
Topics: Animals; Cognition Disorders; Depression; Glutamic Acid; Humans; Serotonin; Serotonin Agents; Synaptic Transmission | 2014 |
Intracellular signaling and approaches to the treatment of schizophrenia and associated cognitive impairment.
Topics: Animals; Antipsychotic Agents; Brain; Cognition Disorders; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Glutamic Acid; Humans; Molecular Targeted Therapy; Nootropic Agents; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Schizophrenia; Schizophrenic Psychology; Signal Transduction | 2014 |
The role of nicotinic receptors in shaping and functioning of the glutamatergic system: a window into cognitive pathology.
Topics: Cognition Disorders; Glutamic Acid; Humans; Molecular Targeted Therapy; Neuronal Plasticity; Neurons; Protein Subunits; Receptors, Nicotinic; Synaptic Transmission | 2014 |
Glutamate and modeling of schizophrenia symptoms: review of our findings: 1990-2014.
Topics: Animals; Antipsychotic Agents; Cognition Disorders; Dopamine Antagonists; Glutamic Acid; Humans; Nucleus Accumbens; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2014 |
Imaging-based neurochemistry in schizophrenia: a systematic review and implications for dysfunctional long-term potentiation.
Topics: Brain; Cognition Disorders; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Long-Term Potentiation; Magnetic Resonance Spectroscopy; Positron-Emission Tomography; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon | 2015 |
Interplay between glutamatergic and GABAergic neurotransmission alterations in cognitive and motor impairment in minimal hepatic encephalopathy.
Topics: Animals; Cognition Disorders; gamma-Aminobutyric Acid; Glutamic Acid; Hepatic Encephalopathy; Humans; Motor Skills Disorders; Synaptic Transmission | 2015 |
Glutamate synapses in human cognitive disorders.
Topics: Animals; Autism Spectrum Disorder; Cognition Disorders; Genetic Predisposition to Disease; Glutamic Acid; Humans; Intellectual Disability; Models, Neurological; Schizophrenia; Synapses | 2015 |
Glutamatergic agents for schizophrenia: current evidence and perspectives.
Topics: Animals; Antipsychotic Agents; Cognition Disorders; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Patient Selection; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2015 |
How does Schizophrenia occur and can delusions be protective to the person? A bird's eye view attempting to Integrate the Neurobiology and Psychology of Schizophrenia.
Topics: Brain; Cognition Disorders; Delusions; Dopamine; Glutamic Acid; Humans; Nerve Net; Neurodevelopmental Disorders; Psychological Theory; Schizophrenic Psychology | 2015 |
Insight into cognitive decline from Zn
Topics: Animals; Brain; Calcium; Cognition; Cognition Disorders; Glucocorticoids; Glutamic Acid; Hippocampus; Humans; Long-Term Potentiation; Neurons; Signal Transduction; Synapses; Zinc | 2016 |
When doors of perception close: bottom-up models of disrupted cognition in schizophrenia.
Topics: Brain; Cognition Disorders; Evoked Potentials, Visual; Glutamic Acid; Humans; Magnetic Resonance Imaging; Memory, Short-Term; Perceptual Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Verbal Behavior | 2009 |
nAChR agonist-induced cognition enhancement: integration of cognitive and neuronal mechanisms.
Topics: Acetylcholine; Animals; Attention; Cognition; Cognition Disorders; Glutamic Acid; Humans; Nerve Net; Neurons; Nicotinic Agonists; Prefrontal Cortex; Receptors, Glutamate; Receptors, Nicotinic; Thalamus | 2009 |
Cognitive dysfunction in schizophrenia: a perspective from the clinic to genetic brain mechanisms.
Topics: Cognition Disorders; Dopamine; Glutamic Acid; Humans; Magnetic Resonance Imaging; Neurosciences; Schizophrenia | 2009 |
The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Biogenic Monoamines; Brain; Cognition Disorders; Depression; Disease Models, Animal; Glutamic Acid; Humans; Neuronal Plasticity; Stress, Psychological; Thiazepines | 2010 |
Mutant mouse models: phenotypic relationships to domains of psychopathology and pathobiology in schizophrenia.
Topics: Animals; Brain; Cognition Disorders; Disease Models, Animal; DNA Mutational Analysis; Dopamine; Genetic Association Studies; Genetic Linkage; Glutamic Acid; Humans; Mice; Mice, Mutant Strains; Phenotype; Schizophrenia; Schizophrenic Psychology | 2010 |
Behavioral and cognitive effects of anti-epileptic drugs.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Neurotransmitter Agents; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Triazines; Vigabatrin | 2010 |
The role of the cerebellum in schizophrenia: from cognition to molecular pathways.
Topics: Animals; Antipsychotic Agents; Cerebellum; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2011 |
Stress-induced deficits in cognition and emotionality: a role of glutamate.
Topics: Animals; Cognition Disorders; Glutamic Acid; Humans; Mood Disorders; Stress, Psychological | 2012 |
From glutamatergic dysfunction to cognitive impairment: boundaries in the therapeutic of the schizophrenia.
Topics: Cognition Disorders; Glutamic Acid; Humans; Receptors, Glutamate; Schizophrenia | 2012 |
Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose.
Topics: Alcoholism; Anesthetics; Anesthetics, Dissociative; Animals; Central Nervous System Depressants; Cognition Disorders; Coma; Drug Overdose; Ethanol; Glutamic Acid; Humans; Illicit Drugs; Ketamine; Neurotoxicity Syndromes; Oxidative Stress; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders; Succinate-Semialdehyde Dehydrogenase | 2012 |
NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia.
Topics: Animals; Awareness; Cerebral Cortex; Cholecystokinin; Cognition Disorders; Cortical Synchronization; Electroencephalography; Glutamic Acid; Humans; Interneurons; Nerve Net; Neural Inhibition; Neuronal Plasticity; Neurons; Parvalbumins; Pyramidal Cells; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction; Synaptic Transmission | 2012 |
Consensus paper: pathological role of the cerebellum in autism.
Topics: Animals; Autistic Disorder; Cell Adhesion Molecules, Neuronal; Cerebellar Diseases; Cerebellum; Cognition Disorders; Disease Models, Animal; Extracellular Matrix Proteins; gamma-Aminobutyric Acid; Gene-Environment Interaction; Glutamic Acid; Humans; Magnetic Resonance Imaging; Mitochondria; Movement Disorders; Nerve Tissue Proteins; Neurotransmitter Agents; Oxidative Stress; Reelin Protein; Serine Endopeptidases | 2012 |
Dysfunctional hippocampal activity affects emotion and cognition in mood disorders.
Topics: Animals; Antidepressive Agents; Behavioral Symptoms; Cognition Disorders; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Mood Disorders; Prefrontal Cortex; Synapses | 2012 |
Chronic hyperammonemia, glutamatergic neurotransmission and neurological alterations.
Topics: Animals; Chronic Disease; Cognition Disorders; Glutamic Acid; Humans; Hyperammonemia; Nervous System Diseases; Synaptic Transmission | 2013 |
Animal models of working memory: insights for targeting cognitive dysfunction in schizophrenia.
Topics: Amphetamine; Animals; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Memory, Short-Term; Models, Animal; Phencyclidine; Prefrontal Cortex; Schizophrenia | 2004 |
Psychopharmacological possibilities in the acute disaster setting.
Topics: Acute Disease; Amygdala; Cognition Disorders; Corticotropin-Releasing Hormone; Disasters; Glutamic Acid; Hippocampus; Humans; Memory Disorders; Neurotransmitter Agents; Norepinephrine; Prefrontal Cortex; Psychopharmacology; Receptors, N-Methyl-D-Aspartate; Stress Disorders, Post-Traumatic | 2004 |
The basal ganglia: anatomy, physiology, and pharmacology.
Topics: Acetylcholine; Basal Ganglia; Cognition Disorders; Corpus Striatum; Frontal Lobe; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Humans; Nerve Net; Positron-Emission Tomography; Rest; Schizophrenia; Serotonin; Substantia Nigra; Thalamus | 2004 |
Implications for atypical antipsychotics in the treatment of schizophrenia: neurocognition effects and a neuroprotective hypothesis.
Topics: Alzheimer Disease; Animals; Antipsychotic Agents; Apoptosis; Catechol O-Methyltransferase; Cognition; Cognition Disorders; Drug Therapy, Combination; Glutamic Acid; Hippocampus; Humans; Neuroprotective Agents; Prefrontal Cortex; Psychotic Disorders; Schizophrenia | 2004 |
On the trail of a cognitive enhancer for the treatment of schizophrenia.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Cognition; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Nootropic Agents; Norepinephrine; Psychopharmacology; Schizophrenia | 2005 |
Hepatic encephalopathy: a dynamic or static condition.
Topics: Cognition Disorders; Glutamic Acid; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Liver Transplantation; Reactive Oxygen Species; Synaptic Transmission | 2005 |
Pharmacotherapy of posttraumatic cognitive impairments.
Topics: Adrenergic Agents; Biogenic Amines; Brain Injuries; Central Nervous System Stimulants; Cholinesterase Inhibitors; Cognition Disorders; Dopamine Agents; Glutamic Acid; Humans; Neurotransmitter Agents | 2006 |
Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations.
Topics: Animals; Cognition Disorders; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Neural Inhibition; Prefrontal Cortex; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission | 2006 |
Glutamatergic approaches to the treatment of cognitive and behavioural symptoms of Alzheimer's disease.
Topics: Alzheimer Disease; Behavioral Symptoms; Cognition Disorders; Glutamic Acid; Humans; Memantine; Neuroprotective Agents; Serotonin Antagonists | 2008 |
Cognitive function in schizophrenic patients.
Topics: Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Clozapine; Cognition Disorders; Dopamine; Glutamic Acid; Humans; Limbic System; Olanzapine; Pirenzepine; Schizophrenia; Schizophrenic Psychology; Serotonin | 1996 |
A pivotal role for glutamate in the pathogenesis of schizophrenia, and its cognitive dysfunction.
Topics: Animals; Cognition Disorders; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology | 1997 |
Pharmacotherapy of cerebral ischemia in cocaine dependence.
Topics: Aspirin; Brain; Brain Ischemia; Cerebrovascular Circulation; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Intracranial Embolism and Thrombosis; Male; Nerve Degeneration; Neuropsychological Tests; Platelet Aggregation Inhibitors; Radionuclide Imaging; Substance Withdrawal Syndrome | 1998 |
Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1 beta?
Topics: Aging; Animals; Antioxidants; Arachidonic Acid; Cognition Disorders; Fatty Acids, Unsaturated; Glutamic Acid; Hippocampus; Humans; Interleukin-1; Lipid Peroxidation; Long-Term Potentiation; Membrane Fluidity; Membrane Lipids; Memory Disorders; Models, Neurological; Phospholipases; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats | 1998 |
Detrimental effects of chronic hypothalamic-pituitary-adrenal axis activation. From obesity to memory deficits.
Topics: Acquired Immunodeficiency Syndrome; Adrenocorticotropic Hormone; Amygdala; Animals; Arginine Vasopressin; Aspartic Acid; Chronic Disease; Cognition Disorders; Corticotropin-Releasing Hormone; Feedback; Glucocorticoids; Glutamic Acid; Hippocampus; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Memory Disorders; Mice; Models, Biological; Obesity; Pituitary-Adrenal System; Rats; Stress, Physiological; Synaptic Transmission | 1998 |
Cognitive deficit in schizophrenia and its neurochemical basis.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; N-Methylaspartate; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology | 1999 |
Cognitive dysfunction in schizophrenia: unifying basic research and clinical aspects.
Topics: Brain; Cognition Disorders; Dopamine; Electroencephalography; Evoked Potentials; Glutamic Acid; Humans; Magnetic Resonance Imaging; Nerve Net; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 1999 |
Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries.
Topics: Acetylcholine; Animals; Biogenic Monoamines; Brain; Brain Diseases; Cognition Disorders; Glutamic Acid; Mental Disorders; Nootropic Agents; Pyrrolidinones; Signal Transduction | 2002 |
5 trial(s) available for glutamic acid and Cognition Disorders
| Article | Year |
|---|---|
Rehabilitation training improves cognitive disorder after cerebrovascular accident by improving BDNF Bcl-2 and Bax expressions in regulating the JMK pathway.
Topics: Aged; Animals; Brain; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Cognition Disorders; Female; Glutamic Acid; Humans; Male; MAP Kinase Signaling System; Maze Learning; Mental Status and Dementia Tests; Middle Aged; Norepinephrine; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Serotonin; Stroke; Stroke Rehabilitation | 2021 |
Cognitive functions in a patient with Parkinson-dementia syndrome undergoing deep brain stimulation.
Topics: Acetylcholine; Aged; Arousal; Attention; Basal Nucleus of Meynert; Cholinergic Fibers; Cognition; Cognition Disorders; Deep Brain Stimulation; Double-Blind Method; Electrodes, Implanted; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lewy Body Disease; Male; Neuropsychological Tests; Parkinsonian Disorders; Prospective Studies; Recovery of Function; Social Behavior; Subthalamic Nucleus; Treatment Outcome | 2009 |
Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial.
Topics: Aged; Aged, 80 and over; Brain; Cognition; Cognition Disorders; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Lewy Body Disease; Male; Memantine; Neuropsychological Tests; Outcome Assessment, Health Care; Parkinson Disease; Patient Selection; Placebo Effect; Placebos; Psychomotor Performance; Reaction Time; Treatment Outcome | 2009 |
AMPA potentiator treatment of cognitive deficits in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biphenyl Compounds; Brain; Cognition Disorders; Double-Blind Method; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Placebos; Receptors, AMPA; Sulfonamides; Synaptic Transmission; Treatment Outcome | 2007 |
Glutamate/aspartate supplementation during cardiopulmonary bypass: effect on postoperative neurocognitive function.
Topics: Aged; Aspartic Acid; Cardiopulmonary Bypass; Cognition; Cognition Disorders; Dietary Supplements; Female; Glutamic Acid; Health Status Indicators; Humans; Incidence; Male; Middle Aged; Postoperative Complications; Postpartum Period; Psychological Tests; Psychometrics; Risk Factors | 2008 |
105 other study(ies) available for glutamic acid and Cognition Disorders
| Article | Year |
|---|---|
Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.
Topics: Animals; Autistic Disorder; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cognition Disorders; Disease Models, Animal; Down Syndrome; Gene Dosage; Gene Expression Regulation; Glutamic Acid; Humans; Intellectual Disability; Mice; Mice, Transgenic; Neurons; Proteomics; Speech Disorders; Synaptic Transmission; Transcription, Genetic | 2021 |
Butanol Extract of Tinospora cordifolia Ameliorates Cognitive Deficits Associated with Glutamate-Induced Excitotoxicity: A Mechanistic Study Using Hippocampal Neurons.
Topics: Animals; Butanols; Cells, Cultured; Cerebellum; Cognition Disorders; Cytokines; Elevated Plus Maze Test; Exploratory Behavior; Female; Gliosis; Glutamic Acid; Hippocampus; Neurons; Neuroprotective Agents; Neurotoxins; Phytotherapy; Plant Extracts; Random Allocation; Rats, Wistar; Receptors, Glutamate; RNA, Messenger; Rotarod Performance Test; Signal Transduction; Single-Blind Method; Solvents; Tinospora | 2020 |
Amyloid Fibril-Induced Astrocytic Glutamate Transporter Disruption Contributes to Complement C1q-Mediated Microglial Pruning of Glutamatergic Synapses.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspartic Acid; Astrocytes; CA1 Region, Hippocampal; Ceftriaxone; Cognition Disorders; Complement C1q; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Microglia; Morris Water Maze Test; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phagocytosis; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Up-Regulation | 2020 |
Neuropsychiatric Manifestations of Wilson Disease: Correlation with MRI and Glutamate Excitotoxicity.
Topics: Adolescent; Adult; Behavioral Symptoms; Brain Mapping; Cognition Disorders; Copper; Feeding and Eating Disorders; Female; Glutamic Acid; Hallucinations; Hepatolenticular Degeneration; Humans; Liver; Magnetic Resonance Imaging; Male; Mood Disorders; Movement Disorders; Neuroimaging; Neurotransmitter Agents; Quetiapine Fumarate; Severity of Illness Index; Young Adult | 2021 |
Precuneus Failures in Subjects of the PSEN1 E280A Family at Risk of Developing Alzheimer's Disease Detected Using Quantitative Electroencephalography.
Topics: Adult; Alanine; Alzheimer Disease; Brain Mapping; Brain Waves; Cognition Disorders; Electroencephalography; Female; Glutamic Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Parietal Lobe; Polymorphism, Single Nucleotide; Presenilin-1; Principal Component Analysis; Psychiatric Status Rating Scales; Young Adult | 2017 |
NSCs promote hippocampal neurogenesis, metabolic changes and synaptogenesis in APP/PS1 transgenic mice.
Topics: Alzheimer Disease; Animals; Aspartic Acid; Cognition Disorders; Creatine; Disease Models, Animal; Glutamic Acid; Hippocampus; Male; Mice, Inbred C57BL; Mice, Transgenic; Neural Stem Cells; Neurogenesis; Synapses | 2017 |
Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function.
Topics: Animals; Astrocytes; Cognition; Cognition Disorders; Doxycycline; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Maze Learning; Mice; Mice, Transgenic; Models, Neurological; Neurons; Prefrontal Cortex; Recognition, Psychology; S100 Calcium Binding Protein beta Subunit; Serine; Signal Transduction; SNARE Proteins; Spatial Behavior; Theta Rhythm | 2017 |
Role of Glutamatergic System in Obsessive-Compulsive Disorder with Possible Therapeutic Implications.
Topics: Brain; Cognition Disorders; Excitatory Amino Acid Agents; Female; Glutamic Acid; Humans; Male; Neuropsychological Tests; Obsessive-Compulsive Disorder; Receptors, Glutamate | 2018 |
Anterior cingulate cortex glutamate and its association with striatal functioning during cognitive control.
Topics: Adolescent; Adult; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Cognition Disorders; Corpus Striatum; Correlation of Data; Female; Glutamic Acid; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Oxygen; Protons; Young Adult | 2018 |
Combination of chick embryo and nutrient mixture prevent D-galactose-induced cognitive deficits, immune impairment and oxidative stress in aging rat model.
Topics: Aging; Animals; Antioxidants; B-Lymphocytes; Body Weight; Brain; Chick Embryo; Cognition Disorders; Disease Models, Animal; Galactose; Glutamic Acid; Intercellular Signaling Peptides and Proteins; Interleukin-2; Interleukin-4; Lipopolysaccharides; Liver; Male; Maze Learning; Memory; NF-kappa B; Nutrients; Ovum; Oxidative Stress; Rats, Sprague-Dawley; Spleen; Stem Cell Factor; Toll-Like Receptor 4 | 2019 |
Effect of kai xin san on learning and memory in a rat model of paradoxical sleep deprivation.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Hippocampus; Learning; Learning Disabilities; Male; Memory; Memory Disorders; Phytotherapy; Rats; Rats, Sprague-Dawley; Sleep Deprivation; Sleep, REM | 2013 |
Erythropoietin protects polychlorinated biphenyl (Aroclor 1254) induced neurotoxicity in mice.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Chlorodiphenyl (54% Chlorine); Cholesterol; Cognition Disorders; Dose-Response Relationship, Drug; Erythropoietin; Glutamic Acid; Male; Maze Learning; Memory; Mice; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Triglycerides | 2013 |
Differential impact of hyponatremia and hepatic encephalopathy on health-related quality of life and brain metabolite abnormalities in cirrhosis.
Topics: Brain; Cognition; Cognition Disorders; Diuretics; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Hyponatremia; Inositol; Liver Cirrhosis; Magnetic Resonance Spectroscopy; Male; Middle Aged; Quality of Life; Sickness Impact Profile | 2013 |
Brain metabolite alterations in young adults at familial high risk for schizophrenia using proton magnetic resonance spectroscopy.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Brain; Cognition Disorders; Family Health; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Young Adult | 2013 |
Trypanosoma evansi infection impairs memory, increases anxiety behaviour and alters neurochemical parameters in rats.
Topics: Acetylcholinesterase; Animals; Anxiety; Ataxia; Behavior, Animal; Calcium-Transporting ATPases; Cognition Disorders; Dogs; Glutamic Acid; Host-Parasite Interactions; Humans; Male; Maze Learning; Nervous System; Parasitemia; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tritium; Trypanosoma; Trypanosomiasis | 2013 |
A novel approach to rapidly prevent age-related cognitive decline.
Topics: Aging; Animals; Behavior, Animal; Biomarkers; Cell Count; Clioquinol; Cognition Disorders; Dendritic Spines; Female; Glutamic Acid; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Neurogenesis; Neuronal Plasticity; Protein Phosphatase 2; Receptors, Glutamate; Synapses; Vesicular Glutamate Transport Protein 1; Zinc | 2014 |
Improved cognitive outcome after progesterone administration is associated with protecting hippocampal neurons from secondary damage studied in vitro and in vivo.
Topics: Animals; Brain Injuries; Cognition Disorders; Disease Models, Animal; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Male; Maze Learning; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Organ Culture Techniques; Progesterone; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors | 2014 |
Abnormal levels of brain metabolites may mediate cognitive impairment in stroke-free patients with cerebrovascular risk factors.
Topics: Aged; Biomarkers; Cerebrovascular Disorders; Cognition; Cognition Disorders; Cross-Sectional Studies; Executive Function; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Memory, Short-Term; Mental Recall; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Risk Factors | 2014 |
Ceftriaxone alleviates early brain injury after subarachnoid hemorrhage by increasing excitatory amino acid transporter 2 expression via the PI3K/Akt/NF-κB signaling pathway.
Topics: Animals; Apoptosis; Astrocytes; Brain Injuries; Caspase 3; Ceftriaxone; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Male; Neoplasm Proteins; Neurons; Neuroprotective Agents; NF-kappa B; Nucleocytoplasmic Transport Proteins; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Subarachnoid Hemorrhage | 2014 |
Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome.
Topics: Aged; Biomarkers; Brain; Cognition Disorders; Female; Follow-Up Studies; Glutamic Acid; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Oxygen; Pyruvic Acid; Subarachnoid Hemorrhage; tau Proteins | 2015 |
Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia.
Topics: Adult; Cognition; Cognition Disorders; Executive Function; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Nerve Net; Neurons; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2014 |
Higher glutamate+glutamine and reduction of N-acetylaspartate in posterior cingulate according to age range in patients with cognitive impairment and/or pain.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cognition Disorders; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pain; Prospective Studies | 2014 |
Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, MAPK pathway activation and decreased CREB phosphorylation in mice hippocampus: reversal by procyanidins extracted from t
Topics: Animals; Biflavonoids; Catechin; Cognition Disorders; CREB-Binding Protein; Glutamic Acid; Hippocampus; Humans; Lotus; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Phosphorylation; Plant Extracts; Proanthocyanidins | 2014 |
Overexpression of heme oxygenase 1 causes cognitive decline and affects pathways for tauopathy in mice.
Topics: Animals; Brain; Cognition Disorders; Cyclin-Dependent Kinase 5; Gene Expression Regulation; Glutamic Acid; Heme Oxygenase-1; Humans; Iron; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Protoporphyrins; Reaction Time; Reactive Oxygen Species; RNA, Messenger; Spatial Learning; Tauopathies | 2015 |
Altered neurotransmission prior to cognitive decline in AβPP/PS1 mice, a model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition Disorders; Disease Models, Animal; Glutamic Acid; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Potassium Chloride; Presenilin-1; Synaptic Transmission | 2015 |
Cognitive impairment induced by permanent bilateral common carotid occlusion exacerbates depression-related behavioral, biochemical, immunological and neuronal markers.
Topics: Analysis of Variance; Animals; Carotid Artery Diseases; Chromatography, High Pressure Liquid; Cognition Disorders; Cues; Depression; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Glycine; Hindlimb Suspension; Hippocampus; Interleukin-6; Male; Maze Learning; Neurons; Rats; Rats, Sprague-Dawley; Stress, Psychological; Swimming; Time Factors | 2015 |
A2A adenosine receptor deletion is protective in a mouse model of Tauopathy.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Animals; Cognition Disorders; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Long-Term Synaptic Depression; Mice, Transgenic; Phosphorylation; Receptor, Adenosine A2A; RNA, Messenger; tau Proteins; Tauopathies; Tissue Culture Techniques; Xanthines | 2016 |
Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Atorvastatin; Cognition Disorders; Glutamic Acid; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intraventricular; Male; Mice; Oxidative Stress; Peptide Fragments; Prefrontal Cortex; Recognition, Psychology; Spatial Learning; Spatial Memory | 2015 |
Deletion of adenosine A2A receptors from astrocytes disrupts glutamate homeostasis leading to psychomotor and cognitive impairment: relevance to schizophrenia.
Topics: Animals; Astrocytes; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Homeostasis; Kainic Acid; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Psychomotor Disorders; Pyrimidines; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Time Factors; Triazoles | 2015 |
Brain and cognition abnormalities in long-term anabolic-androgenic steroid users.
Topics: Adult; Amygdala; Anabolic Agents; Androgens; Brain; Case-Control Studies; Cognition Disorders; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Hypertrophy; Inositol; Magnetic Resonance Imaging; Male; Neural Pathways; Neuroimaging; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy | 2015 |
Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.
Topics: Animals; Cell Cycle; Cell Movement; Cognition Disorders; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neurons; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation | 2016 |
Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression.
Topics: Alzheimer Disease; Animals; Brain Chemistry; Cognition Disorders; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Maze Learning; Mice; Mice, Transgenic; Neuroprotective Agents; Riluzole; Synapses; tau Proteins; Tauopathies; Vesicular Glutamate Transport Protein 1 | 2015 |
Conditioned medium from the stem cells of human dental pulp improves cognitive function in a mouse model of Alzheimer's disease.
Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cognition Disorders; Culture Media, Conditioned; Cytokines; Dental Pulp; Disease Models, Animal; Embryo, Mammalian; Glutamic Acid; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Neurons; Peptide Fragments; Recognition, Psychology; Stem Cells | 2015 |
Executive function deficits and glutamatergic protein alterations in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Brain; Cognition Disorders; Disease Models, Animal; Executive Function; Gait Disorders, Neurologic; Gene Expression Regulation; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neuropsychological Tests; Tyrosine 3-Monooxygenase; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2015 |
Chronic Hyponatremia Causes Neurologic and Psychologic Impairments.
Topics: Animals; Astrocytes; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cells, Cultured; Chronic Disease; Cognition Disorders; Disease Models, Animal; Fear; Gait Disorders, Neurologic; Glutamic Acid; Hyponatremia; Inappropriate ADH Syndrome; Male; Memory Disorders; Microdialysis; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Sodium; Synapses | 2016 |
Reduced cortical thickness in patients with acute-on-chronic liver failure due to non-alcoholic etiology.
Topics: Acute-On-Chronic Liver Failure; Adult; Aspartic Acid; Brain; Case-Control Studies; Cognition; Cognition Disorders; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Inositol; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Software; Treatment Outcome | 2015 |
Is riluzole a new drug for Alzheimer's disease?
Topics: Animals; Cognition Disorders; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neuroprotective Agents; Riluzole; tau Proteins; Tauopathies | 2015 |
PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity.
Topics: Animals; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; In Vitro Techniques; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Prefrontal Cortex; rap GTP-Binding Proteins; Recognition, Psychology; Synapses; Tumor Suppressor Proteins | 2015 |
NF-κB Inhibition Resolves Cognitive Deficits in Experimental Type 2 Diabetes Mellitus through CREB and Glutamate/GABA Neurotransmitters Pathway.
Topics: Animals; Avoidance Learning; Blood Glucose; Brain; Cognition Disorders; CREB-Binding Protein; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Insulin; Male; Maze Learning; NF-kappa B; Nitriles; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Signal Transduction; Sulfones | 2016 |
TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Decline.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Cognition Disorders; Disease Models, Animal; Female; Glutamic Acid; Hypoxia-Ischemia, Brain; Immunoblotting; Male; Maze Learning; Myelin Sheath; Neurogenesis; Neuroprotective Agents; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley | 2016 |
Neurometabolite Alterations Associated With Cognitive Performance in Perinatally HIV-Infected Children.
Topics: Adolescent; AIDS Dementia Complex; Aspartic Acid; Brain; CD4 Lymphocyte Count; Child; Choline; Cognition Disorders; Cohort Studies; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Inositol; Magnetic Resonance Spectroscopy; Male; Neurofilament Proteins; Neuropsychological Tests; Reference Values; tau Proteins | 2016 |
Methylglyoxal can mediate behavioral and neurochemical alterations in rat brain.
Topics: Analysis of Variance; Animals; Anxiety; Brain; Cognition Disorders; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; In Vitro Techniques; Infusions, Intraventricular; Locomotion; Male; Maze Learning; Pyruvaldehyde; rab GTP-Binding Proteins; Rats; Rats, Wistar; Recognition, Psychology; S100 Calcium Binding Protein beta Subunit; Time Factors | 2016 |
Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia.
Topics: Aggression; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anxiety; Behavior, Animal; Cognition; Cognition Disorders; Corticosterone; Disease Models, Animal; Glutamic Acid; Hippocampus; Housing, Animal; In Vitro Techniques; Male; Maze Learning; Mice; Motor Activity; Peptide Fragments; Recognition, Psychology; Social Isolation; Synaptic Transmission; Time Factors | 2016 |
Gastrin-releasing peptide facilitates glutamatergic transmission in the hippocampus and effectively prevents vascular dementia induced cognitive and synaptic plasticity deficits.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Cognition Disorders; Dementia, Vascular; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Gastrin-Releasing Peptide; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Maze Learning; Nerve Net; Neurokinin B; Rats; Rats, Wistar; Synaptic Transmission; Time Factors | 2017 |
Kai Xin San aqueous extract improves Aβ
Topics: Acetylcholine; Amyloid beta-Peptides; Animals; Behavior, Animal; Cognition; Cognition Disorders; Drugs, Chinese Herbal; Glutamic Acid; Hippocampus; Learning; Male; Neuroprotective Agents; Peptide Fragments; Phytotherapy; Rats, Wistar; Reward | 2017 |
Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus.
Topics: Animals; Animals, Newborn; Cognition Disorders; Dentate Gyrus; Disease Models, Animal; Electroporation; Excitatory Postsynaptic Potentials; Fear; Genes, Reporter; Glutamic Acid; HEK293 Cells; Humans; Male; Maze Learning; Mice; Mice, Knockout; Neurons; Post-Synaptic Density; Receptors, AMPA; RNA Interference; RNA, Small Interfering; Schizophrenia; Sensory Gating; Synaptic Transmission; Vesicular Transport Proteins | 2017 |
Prenatal melamine exposure impairs spatial cognition and hippocampal synaptic plasticity by presynaptic and postsynaptic inhibition of glutamatergic transmission in adolescent offspring.
Topics: Animals; Behavior, Animal; Cognition; Cognition Disorders; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Neuronal Plasticity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Spatial Learning; Synaptic Transmission; Triazines | 2017 |
Preserving brain function in a comatose patient with septic hyperpyrexia (41.6 °C): a case report.
Topics: Adult; Amantadine; Anticonvulsants; Brain; Brain Injuries; Cognition Disorders; Coma; Dopamine Agents; Drug Therapy, Combination; Glutamic Acid; Humans; Levetiracetam; Male; Malignant Hyperthermia; Piracetam; Tomography, X-Ray Computed | 2017 |
Immunological alteration & toxic molecular inductions leading to cognitive impairment & neurotoxicity in transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cognition Disorders; Cytokines; Disease Models, Animal; Flow Cytometry; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Inflammation; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Oxidative Stress | 2017 |
Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel.
Topics: Alanine; Animals; Arginine; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, R-Type; Cation Transport Proteins; Cognition Disorders; Genotype; Glutamic Acid; Glycine; GTP-Binding Proteins; Ion Channel Gating; Kinetics; Membrane Potentials; Mutation; Phenotype; Rats; Syndrome; Valine; Xenopus | 2008 |
[Paradoxical increase in glutamatergic synaptic terminations in mild cognitive impairment due to Alzheimer's disease].
Topics: Alzheimer Disease; Animals; Cognition Disorders; Female; Frontal Lobe; Glutamic Acid; Humans; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Tissue Proteins; Neurites; Presynaptic Terminals; Receptors, Glutamate; Receptors, Presynaptic; Synaptic Transmission | 2008 |
Astroglial and cognitive effects of chronic cerebral hypoperfusion in the rat.
Topics: Animals; Astrocytes; Biomarkers; Carotid Stenosis; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Male; Maze Learning; Memory Disorders; Nerve Growth Factors; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Synaptic Transmission | 2009 |
Neurometabolite concentrations in gray and white matter in mild traumatic brain injury: an 1H-magnetic resonance spectroscopy study.
Topics: Adult; Affective Symptoms; Axons; Biomarkers; Body Water; Brain; Brain Injuries; Cognition Disorders; Corpus Callosum; Creatine; Diffuse Axonal Injury; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Phosphocreatine; Young Adult | 2009 |
Synaptopathy under conditions of altered gravity: changes in synaptic vesicle fusion and glutamate release.
Topics: Acridine Orange; Adenosine Triphosphate; Animals; Brain; Calcium Signaling; Cell Compartmentation; Cognition Disorders; Cytoplasm; Disease Models, Animal; Exocytosis; Fluorescent Dyes; Glutamic Acid; Hypergravity; Magnesium; Male; Membrane Fusion; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission; Synaptic Vesicles; Synaptosomes | 2009 |
Altered prefrontal glutamate-glutamine-gamma-aminobutyric acid levels and relation to low cognitive performance and depressive symptoms in type 1 diabetes mellitus.
Topics: Adult; Cognition Disorders; Depression; Diabetes Mellitus, Type 1; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycated Hemoglobin; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex | 2009 |
Mazindol attenuates ketamine-induced cognitive deficit in the attentional set shifting task in rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Cognition Disorders; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Imidazoles; Indoles; Ketamine; Male; Mazindol; Microdialysis; Neuropsychological Tests; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley | 2010 |
Neurometabolic changes in the acute phase after sports concussions correlate with symptom severity.
Topics: Acute Disease; Adult; Aspartic Acid; Athletic Injuries; Brain; Brain Concussion; Cognition Disorders; Down-Regulation; Energy Metabolism; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory Disorders; Motor Cortex; Neuropsychological Tests; Predictive Value of Tests; Self-Assessment; Severity of Illness Index; Young Adult | 2010 |
Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Astrocytes; Brain; Calcineurin; Cells, Cultured; Cognition Disorders; Embryo, Mammalian; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Male; NFATC Transcription Factors; Peptide Fragments; Protein Transport; Rats; Signal Transduction; Transfection | 2009 |
Dietary branched chain amino acids ameliorate injury-induced cognitive impairment.
Topics: Amino Acids, Branched-Chain; Animals; Brain Injuries; Cognition Disorders; Diet; Glutamic Acid; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Synaptic Transmission | 2010 |
Maternal thiamine restriction during lactation induces cognitive impairments and changes in glutamate and GABA concentrations in brain of rat offspring.
Topics: Analysis of Variance; Animals; Animals, Suckling; Brain; Cognition Disorders; Energy Metabolism; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Lactation; Male; Maze Learning; Milk; Nutritive Value; Prefrontal Cortex; Rats; Reaction Time; Thalamus; Thiamine; Thiamine Deficiency; Time Factors | 2010 |
Drug therapies for cognitive impairment and dementia.
Topics: Aged; Caprylates; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Food, Formulated; Ginkgo biloba; Glutamic Acid; Humans; Nootropic Agents; Phytotherapy; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Triglycerides | 2010 |
A heterozygous mutation of the insulin-like growth factor-I receptor causes retention of the nascent protein in the endoplasmic reticulum and results in intrauterine and postnatal growth retardation.
Topics: Amino Acid Substitution; Birth Weight; Body Size; Cognition Disorders; Endoplasmic Reticulum; Exons; Female; Fetal Growth Retardation; Glutamic Acid; Growth Disorders; Heterozygote; Humans; Infant, Newborn; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Intellectual Disability; Microcephaly; Mutation, Missense; Polymerase Chain Reaction; Receptor, IGF Type 1; Valine | 2010 |
The impact of blood pressure on hippocampal glutamate and mnestic function.
Topics: Adult; Aspartic Acid; Blood Pressure; Cognition; Cognition Disorders; Female; Germany; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Hypertension; Linear Models; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Neuropsychological Tests; Young Adult | 2011 |
Brain metabolism and cognitive impairment in HIV infection: a 3-T magnetic resonance spectroscopy study.
Topics: Adult; Antiretroviral Therapy, Highly Active; Brain; Cognition Disorders; Cohort Studies; Female; Glutamic Acid; Glutamine; HIV Infections; HIV Seropositivity; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2010 |
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.
Topics: Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcineurin; Calcineurin Inhibitors; Calcium; Calpain; Case-Control Studies; Cell Culture Techniques; Cell Fractionation; Cognition Disorders; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Female; Glutamic Acid; Hippocampus; Humans; Male; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Retrospective Studies; Signal Transduction | 2011 |
Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla.
Topics: Adult; Age Factors; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuropsychological Tests; Protons; Schizophrenia; Schizophrenic Psychology | 2011 |
Lower brain glutamate is associated with cognitive deficits in HIV patients: a new mechanism for HIV-associated neurocognitive disorder.
Topics: Adult; AIDS Dementia Complex; Brain; Cognition Disorders; Female; Glutamic Acid; HIV Infections; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged | 2010 |
Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Benzodiazepines; Choice Behavior; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Impulsive Behavior; Male; Microdialysis; Neuropsychological Tests; Olanzapine; Piperazines; Prefrontal Cortex; Quinolones; Rats; Reaction Time; Schizophrenia; Serotonin; Time Factors | 2011 |
Elevated cerebral glutamate and myo-inositol levels in cognitively normal middle-aged adults with metabolic syndrome.
Topics: Adult; Brain Chemistry; Cognition Disorders; Disease Progression; Female; Glutamic Acid; Humans; Inositol; Intelligence Tests; Language; Magnetic Resonance Spectroscopy; Male; Memory; Metabolic Syndrome; Middle Aged; Neuropsychological Tests; Periaqueductal Gray; Psychomotor Performance; Space Perception; Visual Perception; Wechsler Scales | 2010 |
Acute stress induces contrasting changes in AMPA receptor subunit phosphorylation within the prefrontal cortex, amygdala and hippocampus.
Topics: Amygdala; Animals; Brain Mapping; Cognition Disorders; Corticosterone; Frontal Lobe; Glutamic Acid; Hippocampus; Immunoassay; Long-Term Potentiation; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Serine | 2010 |
Altered presynaptic ultrastructure in excitatory hippocampal synapses of mice lacking dystrophins Dp427 or Dp71.
Topics: Animals; Cognition Disorders; Disease Models, Animal; Dystrophin; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Neuronal Plasticity; Presynaptic Terminals; Protein Isoforms; Synaptic Vesicles | 2011 |
Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist.
Topics: Animals; Cognition Disorders; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Folic Acid; Glutamic Acid; Homocysteine; Humans; Injections, Spinal; Male; Memory Disorders; Methotrexate; Rats; Rats, Long-Evans; Recognition, Psychology | 2011 |
Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia.
Topics: Animals; Cognition Disorders; Dementia; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Hippocampus; Humans; Male; Microinjections; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Neuroglia; Okadaic Acid; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2012 |
Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Cerebellum; Cognition; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Ginsenosides; Glutamic Acid; Humans; Learning; Memory; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Phosphorylation | 2012 |
Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Cognition; Cognition Disorders; Disease Models, Animal; Galantamine; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Nootropic Agents; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Nicotinic; Schizophrenia | 2012 |
Dual task abilities as a possible preclinical marker of Alzheimer's disease in carriers of the E280A presenilin-1 mutation.
Topics: Adult; Alanine; Alzheimer Disease; Analysis of Variance; Biomarkers; Cognition Disorders; Female; Glutamic Acid; Humans; Male; Mental Recall; Middle Aged; Mutation; Neuropsychological Tests; Presenilin-1; Regression Analysis; ROC Curve; Statistics, Nonparametric | 2012 |
Protective effect of menthol on β-amyloid peptide induced cognitive deficits in mice.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Behavior, Animal; Brain; Cognition Disorders; Disease Models, Animal; Glutamic Acid; Male; Maze Learning; Memory Disorders; Menthol; Mice | 2012 |
Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Cognition Disorders; Electrochemical Techniques; Female; Glutamic Acid; Kynurenic Acid; Kynurenine; Male; Maze Learning; Memory; Microdialysis; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Spatial Behavior | 2012 |
Brain metabolite alterations and cognitive dysfunction in early Huntington's disease.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Cognition Disorders; Female; Glutamic Acid; Humans; Huntington Disease; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Regression Analysis; Trinucleotide Repeat Expansion | 2012 |
Common variants in MAGI2 gene are associated with increased risk for cognitive impairment in schizophrenic patients.
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Case-Control Studies; Cognition Disorders; Genetic Association Studies; Genetic Predisposition to Disease; Glutamic Acid; Guanylate Kinases; Humans; Japan; Neuropsychological Tests; Polymorphism, Single Nucleotide; Schizophrenia | 2012 |
Cognitive dysfunction and glutamate reuptake: effect of EAAT2 polymorphism in schizophrenia.
Topics: Adolescent; Adult; Cognition Disorders; Excitatory Amino Acid Transporter 2; Female; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Male; Memory, Short-Term; Middle Aged; Polymorphism, Genetic; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Young Adult | 2012 |
Indirect effects of elevated body mass index on memory performance through altered cerebral metabolite concentrations.
Topics: Adult; Aspartic Acid; Biomarkers; Body Mass Index; Brain; Choline; Cognition Disorders; Creatine; Female; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Neuropsychological Tests; Obesity; Protons | 2012 |
Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis.
Topics: Adult; Arginine; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Cross-Sectional Studies; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Inositol; Liver Cirrhosis; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prospective Studies | 2013 |
Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Exploratory Behavior; Glutamic Acid; Humans; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Mutation; Nomifensine; Norepinephrine; Photic Stimulation; Presenilin-1; Recognition, Psychology; Statistics, Nonparametric; tau Proteins | 2012 |
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.
Topics: Animals; Association Learning; Cell Nucleus; Cognition Disorders; Dentate Gyrus; Discrimination Learning; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Mice, Inbred C57BL; Mice, Knockout; Miniature Postsynaptic Potentials; Nerve Tissue Proteins; Neurogenesis; Phenotype; Phosphorylation; Post-Synaptic Density; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Signal Detection, Psychological; Space Perception | 2012 |
Reduced posterior cingulate glutamate measured by magnetic resonance spectroscopy in hyperthyroidism.
Topics: Adult; Aspartic Acid; Choline; Cognition Disorders; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Hyperthyroidism; Magnetic Resonance Spectroscopy; Male; Young Adult | 2012 |
Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Cognition; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Fetus; Glutamic Acid; Male; Memory; Memory Disorders; Neuroprotective Agents; Phytotherapy; Plant Extracts; Polygala; Rats; Rats, Sprague-Dawley | 2002 |
Changes of mGluR4 and the effects of its specific agonist L-AP4 in a rodent model of diffuse brain injury.
Topics: Aminobutyrates; Animals; Behavior, Animal; Brain; Brain Injuries; Cell Count; Cognition Disorders; Diffuse Axonal Injury; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Movement Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger; Synaptic Transmission; Treatment Outcome | 2003 |
Glutamate receptor binding in the frontal cortex and dorsal striatum of aged rats with impaired attentional set-shifting.
Topics: Aging; Animals; Attention; Binding, Competitive; Cognition Disorders; Down-Regulation; Excitatory Amino Acid Agonists; Frontal Lobe; Glutamic Acid; Gyrus Cinguli; Maze Learning; Neostriatum; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, Glutamate; Set, Psychology; Space Perception; Tritium | 2003 |
Prenatal administration of morphine decreases CREBSerine-133 phosphorylation and synaptic plasticity range mediated by glutamatergic transmission in the hippocampal CA1 area of cognitive-deficient rat offspring.
Topics: Animals; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Maze Learning; Morphine; Morphine Dependence; Neuronal Plasticity; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2003 |
Poorer cognitive performance in humans with mild cognitive impairment carrying the T variant of the Glu/Asp NOS3 polymorphism.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Chi-Square Distribution; Cognition Disorders; Female; Genetic Variation; Genotype; Glutamic Acid; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic | 2004 |
Antiepileptic effects of botulinum neurotoxin E.
Topics: Animals; Anticonvulsants; Botulinum Toxins; Cell Death; Cognition Disorders; Convulsants; Drug Evaluation, Preclinical; Electric Stimulation; Electroencephalography; Epilepsies, Partial; Epilepsy, Generalized; Glutamic Acid; Hippocampus; Injections, Intralesional; Kainic Acid; Kindling, Neurologic; Maze Learning; Membrane Proteins; Nerve Tissue Proteins; Pyramidal Cells; Random Allocation; Rats; Rats, Long-Evans; Stereotaxic Techniques; Synaptosomal-Associated Protein 25 | 2005 |
Combined alpha2 and D2/3 receptor blockade enhances cortical glutamatergic transmission and reverses cognitive impairment in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cerebral Cortex; Clozapine; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Idazoxan; In Vitro Techniques; Male; Maze Learning; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Synaptic Transmission | 2005 |
Neuroprotection in cardiac surgery.
Topics: Animals; Cardiac Surgical Procedures; Cognition Disorders; Consciousness Disorders; Disease Models, Animal; Dogs; Glutamic Acid; Humans; Neurons; Neuroprotective Agents; Nitric Oxide; Postoperative Complications; Risk Factors | 2005 |
NMDA receptor-independent long-term depression correlates with successful aging in rats.
Topics: Adaptation, Physiological; Aging; Animals; Cognition; Cognition Disorders; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Long-Term Synaptic Depression; Maze Learning; Memory Disorders; Neuronal Plasticity; Organ Culture Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Species Specificity; Synaptic Transmission; Type C Phospholipases | 2005 |
[Also consider non-cognitive disorders].
Topics: Aged; Alzheimer Disease; Brain; Cognition Disorders; Depressive Disorder; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; Mental Disorders; Treatment Outcome | 2005 |
Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Cognition Disorders; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Recall; Middle Aged; Neurons; Phosphocreatine; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Verbal Learning | 2007 |
A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders.
Topics: Child; Child Behavior Disorders; Child Development Disorders, Pervasive; Child, Preschool; Cognition Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Intelligence; Language Development Disorders; Male; Memantine; Memory Disorders; Neuropsychological Tests; Prospective Studies; Treatment Outcome | 2006 |
Neurochemical and structural correlates of executive dysfunction in schizophrenia.
Topics: Adult; Amygdala; Aspartic Acid; Atrophy; Brain; Cognition Disorders; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex; Problem Solving; Schizophrenia, Paranoid | 2008 |
Paradoxical upregulation of glutamatergic presynaptic boutons during mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Cognition Disorders; Cohort Studies; Disease Progression; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Neurons; Neuropsychological Tests; Plaque, Amyloid; Prefrontal Cortex; Presynaptic Terminals; Severity of Illness Index; Up-Regulation | 2007 |
Low striatal glutamate levels underlie cognitive decline in the elderly: evidence from in vivo molecular spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cerebellum; Cognition; Cognition Disorders; Corpus Striatum; Efferent Pathways; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Neuropsychological Tests; Prefrontal Cortex; Young Adult | 2008 |
Elevated 3T proton MRS glutamate levels associated with poor Continuous Performance Test (CPT-0X) scores and genetic risk for schizophrenia.
Topics: Adult; Attention; Cognition Disorders; Creatine; Discrimination, Psychological; Female; Frontal Lobe; Genetic Predisposition to Disease; Glutamic Acid; Humans; Inhibition, Psychological; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Pattern Recognition, Visual; Psychomotor Performance; Reaction Time; Risk; Schizophrenia; Schizophrenic Psychology; Schizotypal Personality Disorder; Siblings | 2008 |
Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study.
Topics: Adult; Aged; Aging; Alzheimer Disease; Cognition Disorders; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memantine | 2008 |
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception | 1993 |
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Escape Reaction; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Learning Disabilities; Male; Maze Learning; Memory Disorders; Microdialysis; Oxidative Stress; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Reperfusion Injury; Spatial Behavior; Swimming; Time Factors | 2000 |